The Mouse Imaging Program (MIP) is a large scale imaging resource supported in part through an NCI U24 grant. The resource provides the larger Harvard/MIT research community with access to state-of-the-art in vivo imaging technologies including high resolution magnetic resonance (MR), computed tomography (CT), positron emission tomography-CT (PET-CT), single photon emission computed tomography-CT (SPECT-CT), fluorescence mediated tomography (FMT) and bioluminescence imaging (BLI). The integrated Program also provides mouse holding facilities for serial imaging, surgery, anesthesia, veterinary care and imaging agents. Image reconstruction, 3D display, fusion, quantitative image analysis and server access are also available. The Program offers periodic training and performs its own research in order to continue to improve existing imaging technologies. Imaging requests from investigators of the Mouse Model of Human Cancers Consortia and recipients of NCI grants are prioritized.
Imaging the Vascular Bone Marrow Niche During Inflammatory Stress.
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.
Efficacy and safety assessment of a TRAF6- targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma.
Dont forget to register for the upcoming Harvard CME course on Molecular Imaging
. The course is being chaired by Drs. Frangioni and Weissleder and features over 30 invited speakers covering all topics of molecular imaging. More information can be found here
2012-04-13: "Magnetic Nanoparticles Predict Diabetes Onset"
- HMS Focus highlights describes developed at CSB a magnetic nanoparticle-based MRI technique for predicting whether and when subjects with a genetic predisposition for diabetes will develop the disease. (pdf