Hwang Lab

Read Bio

Phone: 617-726-6906

Email: whwang1@mgh.harvard.edu

Follow @DrWilliamHwang

 Visit Hwang Lab homepage - https://whwanglab.mgh.harvard.edu

Recent Publications

• Khan MA, Chang J, Song Y, Shetty AC, Nguyen T, Waters DN, Chowdhury DD, Simms E, Chan A, Tseng HW, Lam C, Patel P, Tran LT, Chen J, Wang JH, Nugent K, Ballew M, Lemtiri-Chlieh G, Carrieri FA, Malek R, Wang H, Thielman NRJ, Li K, Park RJ, Hwang WL, Zheng L, Gabrielson K, Tran PT, Lafargue A

  Twist1 overexpression models an aggressive subtype of pancreatic ductal adenocarcinoma in vivo. Lab Anim (NY). 2026;:ePub - PMID: 42174151 - DOI: 10.1038/s41684-026-01729-2

• Gong D, Guo JA, Su J, Cetinkaya S, Hennessey C, Yu P, Jambhale A, Wang PL, Caldwell NJ, Lam A, Wang J, Shiau C, Kapner KS, Dilly J, Abbassi L, Chugh S, Dasgupta S, Nowak J, Wolpin BM, Zhang ML, Mino-Kenudson M, Jacks T, Aguirre AJ, Hwang WL

  GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma. Cell Rep. 2026;45(5):117314 - PMID: 42048185 - DOI: 10.1016/j.celrep.2026.117314

• Arbesfeld-Qiu JM, Cho JW, Nguyen PTT, Lester NA, Su J, Shiau C, Guo JA, Hoffman H, Caldwell N, Muratani S, Galvan M, Proctor JE, Ely Z, Wang S, Ganci M, Dries R, Hong T, Wo J, Boland G, Fernandez-Del Castillo C, Ferrone CR, Heaphy CM, Zhang ML, Mino-Kenudson M, Hemberg M, Hwang WL

  Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumors. Clin Cancer Res. 2026;32(12):2449-2466 - PMID: 41849229 - PMCID: PMC13118131 - DOI: 10.1158/1078-0432.CCR-25-2565

• Lin EW, Pathak P, O'Shea A, Awasthi B, Phillips IE, Kocher JR, Song Y, Raabe MJ, Xu KH, Patel BK, Lester N, Bae JW, Zhang ML, Nieman LT, Blaszkowsky LS, Walsh EP, Parikh AR, Hansen A, Caufield J, Newbert G, Asombang AW, Casey B, Cohen J, Jacobson BC, Krishnan K, Uppot R, Weissleder R, Horick NK, Hwang WL, Harisinghani MG, Ting DT, Weekes CD

  Therapeutic Targeting of Epithelial Mesenchymal Cellular Plasticity in Pancreatic Cancer. Clin Cancer Res. 2025;32(5):869-882 - PMID: 41364739 - DOI: 10.1158/1078-0432.CCR-25-2052

• Gong D, Liu R, Cui Y, Rhodes M, Bae JW, Beechem JM, Hwang WL

  Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer. Sci Adv. 2025;11(42):eadx0632 - PMID: 41105767 - PMCID: PMC12533583 - DOI: 10.1126/sciadv.adx0632

• More publications ...

News