Weissleder

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Ralph Weissleder's Lab

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The Lab has a unique operation. We have always focused on selecting ideas that would have the greatest positive impact for humanity (for some current projects see here). Our primary focus is to:

  • Obtain a deeper understanding of human biology in health and disease
  • Translate new biological understanding into clinically useful diagnostics
  • Identify new therapeutic approaches and drug targets
The lab uses a variety of tools and platforms (bioimaging, chemical biology, bioengineering) for data acquisition. In general, we aim at obtaining:
  • Quantitative in vivo measurements
  • Systems-wide global measurements
  • Dynamic, serial measurements
  • An fine-grained understanding of in vivo function
We strongly encourage an unusual interdisciplinary approach, fostering collaboration between scientists and clinicians from diverse backgrounds. This convergence approach has led to many exciting discoveries and innovations at the Weissleder Lab.

Recent Publications (more...)

Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R
Evolution of macromolecular complexity in drug delivery systems
Nat Rev Chem. 2017;1:0063
Miller MA, Weissleder R
Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior
Adv Drug Deliv Rev. 2017;113:61-86
Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H
Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection.
ACS Nano. 2017;:ePub - PMID: 28792732
Im H, Lee K, Weissleder R, Lee H, Castro CM
Novel nanosensing technologies for exosome detection and profiling.
Lab Chip. 2017;17(17):2892-2898 - PMID: 28745363

Recent News (more...)

2017-08-10: CSB has been named as one of the NCI Innovative Research in Cancer Nanotechnology (IRCNs). The IRCNs engage in directed, product-focused research that aims to translate cutting-edge science and technology into the next generation of diagnostic and therapeutic tools. These platforms serve as the core technologies for a wide array of specific applications that will ultimately benefit cancer patients.
2017-06-15: Ralph Weissleder, MD, PhD is in the top 100 of Highly Cited Researchers.
2017-05-19: Sean Arlauckas of the Weissleder lab won the Tayyaba Hasan, PhD ORCD Poster of Prestige Award for top abstract at this year’s MGH Research Fellow Poster Celebration. The prize recognizes outstanding contributions to the MGH research enterprise.