About

Ralph Weissleder's Lab

Weissleder_research

My laboratory has currently three major areas of interest: 1) Quantitative single cell analysis of cancers during drug treatments in vivo (systems pharmacology); 2) Use of chemical biology and bioorthogonal chemistries to perturb and analyze protein networks to identify new drug targets; 3) Use of next-gen sensing technologies ("chips") for real-time analysis of human biology.

The lab uses a variety of tools and platforms for data acquisition. In general, we aim at obtaining:

Recent Publications (more...)

Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut.
Proc Natl Acad Sci U S A. 2014;:ePub - PMID: 24753589
Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H*
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;:ePub - PMID: 24752081
Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherrer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium.
Circ Res. 2014;:ePub - PMID: 24625784
Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS,Reiner T
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis
ChemistryOpen. 2014;:ePub

Recent News (more...)

2014-04-01: Aaron Aguirre, MD, PhD has been awarded a John S. LaDue Memorial Fellowship at Harvard Medical School. Congratulations, Aaron!
2014-03-07: Aaron Aguirre, MD, PhD has been awarded the Eugene Braunwald Fellowship in Cardiovascular Medicine and Science. Congratulations, Aaron!
2014-02-21: NIH Director's Blog features CSB work on DNA Barcoding (pdf)
2014-01-15: CSB paper published in Science Translational Medicine is featured in the Focus commentary
2013-12-17: Simple, Portable Test Could Make Blood Transfusions Safer - Chemical & Engineering News is featuring CSB work. (pdf)

Weissleder

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