Ralph Weissleder's Lab
The Lab has a unique operation. We have always focused on selecting ideas that would have the greatest positive impact for humanity (for some current projects see here). Our primary focus is to:
- Obtain a deeper understanding of human biology in health and disease
- Translate new biological understanding into clinically useful diagnostics
- Identify new therapeutic approaches and drug targets
- Quantitative in vivo measurements
- Systems-wide global measurements
- Dynamic, serial measurements
- An fine-grained understanding of in vivo function
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.
Nat Commun. 2017;8:14293 - PMID: 28176769
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.
Quantitating drug-target engagement in single cells in vitro and in vivo.
Nat Chem Biol. 2016;13(2):168-173 - PMID: 27918558
Facile silicification of plastic surface for bioassays.
Chem Commun. 2017;53(13):2134-2137 - PMID: 28134385
2017-02-10: Ralph Weissleder, MD PhD is one of more than 100 scientists and leaders who signed the letter “Convergence: The future of health”. It was released in Science. (pdf)
2017-02-09: Miles Miller, PhD and Kevin King, MD, PhD have been selected to serve as Associate Scientific Advisors (ASAs) for Science's sister journal, Science Translational Medicine, for 2017-2018.
2016-12-14: Sean Arlauckas, PhD of the Weissleder Lab received the honor of “Top Poster” at the 2nd Annual Symposium of the Harvard Program in Therapeutic Sciences. Congratulations, Sean!
2016-12-13: Ralph Weissleder, MD, PhD has been elected as a member of the National Academy of Inventors. The NAI Fellows Selection Committee has chosen Ralph for induction as he “has demonstrated a highly prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development, and the welfare of society.” Congratulations on this great achievement and recognition as a truly prolific academic inventor!
2016-10-07: Divya Pathania, PhD was selected to receive Translational Research Award for Lymphoma-D3 project at MGH Clinical Research Day. Congratulations, Divya!