Ralph Weissleder's Lab
The Lab has a unique operation. We have always focused on selecting ideas that would have the greatest positive impact for humanity (for some current projects see here). Our primary focus is to:
- Obtain a deeper understanding of human biology in health and disease
- Translate new biological understanding into clinically useful diagnostics
- Identify new therapeutic approaches and drug targets
- Quantitative in vivo measurements
- Systems-wide global measurements
- Dynamic, serial measurements
- An fine-grained understanding of in vivo function
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.
J Exp Med. 2017;:ePub - PMID: 28978634
PD-L1 is an activation-independent marker of brown adipocytes.
Imaging the emergence and natural progression of spontaneous autoimmune diabetes.
2017-10-04: Aaron Aguirre, MD, PhD has received a 2017 Physician/Scientist Development Award for “Morphology and Dynamic Functions of Pericytes in the Heart.” The project will use state-of-the-art microscopy techniques to better understand the role of pericytes—unique cells that line the outer walls of the smallest blood vessels in the heart.
2017-10-04: "Observing The Development Of Type 1 Diabetes" - CSB publication has been highlighted on Snapshot of Science at Mass General
2017-08-10: CSB has been named as one of the NCI Innovative Research in Cancer Nanotechnology (IRCNs). The IRCNs engage in directed, product-focused research that aims to translate cutting-edge science and technology into the next generation of diagnostic and therapeutic tools. These platforms serve as the core technologies for a wide array of specific applications that will ultimately benefit cancer patients.
2017-07-24: Jouha Min, PhD (Weissleder Lab) received the Masoumeh Ghaderi Prize for Best Sound-Bite Presentation (1st Place) at the 5th Annual Workshop on Micro- and Nanotechnologies for Medicine: Emerging Frontiers and Applications.