The Biomedical Engineering program at CSB brings together four different labs (Lee, Im, Castro and Weissleder) interested in medical applications of next generations technologies. Members of the Program meet weekly to discuss the latest research, plan future experiments, review the literature and interact with other groups. Some of the innovative technologies developed to date are shown below.
Microfluidic chip for exosome analysis
This chip integrates pneumatic valves, membrance filters, and a microcoil. Exosomes are magnetically labeled on chip, and detected by NMR.
Microfiltration device for exosome collection
The device directly filters whole bloods and collects extracellular vesicles. The filter sets are clamped by a pair of ring magnets.
Nanoplasmonic exosome (nPLEX) sensor
The sensor contains nanohole arrays that sustain surface plasmon resonance. It detect exosomes in a label-free manner.
Microfluidic cell sorter
Based on size separation, this device enriches CTCs from unprocessed whole bloods, and allows for on-chip culture and molecular profiling.