Hakho Lee

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Hakho Lee's Lab

Biomedical Engineering Program

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Highly sensitive, fast and cost-effective diagnostic systems can have far-reaching implications in medicine and life sciences. The primary goal of our laboratory is to develop such platforms by bringing together ideas and techniques embodied in physics and engineering. We further seek to apply the developed platforms to rigorously and quantitatively analyze living systems, with the ultimate aim of promoting human well-being. To achieve these goals, we are guided by the following principles:
Many new diagnostic technologies have resulted from these efforts, and we are actively pursing their clinical translations.

Recent Publications (more...)

Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB*
Single-cell magnetic imaging using a quantum diamond microscope.
Nat Methods. 2015;:ePub - PMID: 26098019
Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H*, Weissleder R*
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Nat Commun. 2015;6:6999 - PMID: 25959588 - PMCID: PMC4430127
Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H*
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone
Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451
Park YI, Im H, Weissleder R, Lee H
Nanostar clustering improves the sensitivity of plasmonic assays.
Bioconjug Chem. 2015;:ePub - PMID: 26102604

Recent News (more...)

2015-06-16: CSB developed nano-plasmonic exosome (”nPLEX”) technology won the Most promising translational research award given by CaNCURE Nanomedicine Program during their annual Nanomedicine Day.
2015-06-05: Divya Pathania, PhD received an award at the MGH ORCD 2015 Research Fellows Poster Celebration
2015-04-08: ACS Nano Podcast Episode 92, March 2015 is featuring an interview with Hakho Lee, PhD. It highlights features and research of acoustic purification of extracellular micro vesicles - PMID: 25672598. (mp3)
2014-11-17: Kisoo Park and Jongmin Park were awarded with the prestigious post-doctoral research fellowship from National Research Foundation, Korea. Congratulations!