Hakho Lee’s Lab
Sensitive, fast and cost-effective diagnostic systems can have far-reaching implications in medicine and life sciences. My laboratory specializes in developing such sensors by bringing together ideas and techniques embodied in physics, engineering, and computation. Our research is guided by core principles – thorough understanding of underlying sensing mechanisms and providing robust engineering solutions. We further apply developed sensors to quantitatively analyze living systems. These efforts are key requisite for finding new biomarkers for early intervention as well as for developing targeted therapies.
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood.
Nanomedicine. 2016;:ePub - PMID: 27993725
Seonki Hong (Poster of Prestige), Chen-Han Huang (Poster of Merit), and Ashley Fenn (Poster of Distinction) received awards at 2016 MGH ORCD Research Fellows Poster Celebration