Hakho Lee's Lab
Biomedical Engineering Program
- Thorough understanding of sensing mechanism. Before developing new detection systems, we put significant efforts in thoroughly studying their underlying physics. This critical task determines the feasibility of a proposed system, and estimates its fundamental limit.
- Engineering solution for robust operation. When implementing the actual systems, we strive to make them highly reliable and easy-to-use. Much emphasis is placed on system reproducibility, packaging, and user-interface.
- Multidisciplinary projects. We value working on multidisciplinary, large-scale projects that tackle challenging problems in biophysics and medicine. Such projects could be a venue for inspiring new technologies as well as expanding the use of emerging technologies. Researchers can also be motivated by new opportunities and interdisciplinary training, rather than being tunneled into a narrow specialty.
Many new diagnostic technologies have resulted from these efforts, and we are actively pursing their clinical translations.
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
Nano-plasmonic exosome diagnostics.
Expert Rev Mol Diagn. 2015;:1-9 - PMID: 25936957
2015-04-08: ACS Nano Podcast Episode 92, March 2015 is featuring an interview with Hakho Lee, PhD. It highlights features and research of acoustic purification of extracellular micro vesicles - PMID: 25672598. (mp3)
2014-11-17: Kisoo Park and Jongmin Park were awarded with the prestigious post-doctoral research fellowship from National Research Foundation, Korea. Congratulations!
2014-10-16: Changwook Min was selected for the CCNE Graduate Student Award. Congratulations!
2014-08-21: CSB, ETRI (Electronic and Telecommunication Research Institute, Korea) and KBRI (Korea Brain Research Institute) have signed an MoU on research collaboration and academic exchange. The agreement is expected to promote international cooperation between these Institutions of complementary expertise, towards developing new sensing technologies.
2014-06-04: Congratulations to Hyungsoon Im, PhD and Miles Miller, PhD who won MGH ORCD 2014 Research Fellows Poster Celebration Awards.