Investigator / Platform Research Area Position
Im, Hyungsoon Engineering, extracellular vesicles, and neurodegenerative diseases Postdoctoral Research Fellow
Im, Hyungsoon Artificial intelligence, deep learning, computer science Postdoctoral Research Fellow
Naxerova, Kamila Cancer genetics and tumor evolution Postdoctoral Research Fellow
Weissleder, Ralph Molecular profiling of cancer cells and microscopy Postdoctoral Research Fellow
Weissleder, Ralph Synthetic chemistry Postdoctoral Research Fellow
Weissleder, Ralph Biomedical engineering Postdoctoral Research Fellow
Chen, John Neuroinflammation Postdoctoral Research Fellow
Aguirre, Aaron Cardiovascular Imaging and Physiology / Advanced Microscopy Postdoctoral Research Fellow
Naxerova, Kamila Computational Biology Research Technician II
More information:

Position: Postdoctoral Research Fellow

Research Area: Engineering, extracellular vesicles, and neurodegenerative diseases

Full/Part Time: Full Time

Investigator: Im, Hyungsoon

Date Posted: 2020-05-07

Description: Postdoctoral research positions are available in the laboratory of Dr. Hyungsoon Im in the Center for Systems Biology (CSB) at the Massachusetts General Hospital (MGH), Harvard Medical School. Recent work in the lab includes the development nanoplasmonic technologies for molecular detection of extracellular vesicles and next-generation sensing technologies for multiplexed cellular analysis. Thematic areas in the lab currently include 1) developing new sensing technologies for clinical translation, 2) investigating roles of EVs as clinical biomarkers in cancers and neurodegenerative diseases, 3) developing novel diagnostic methods for global health. Please see the references for details: Theranostics, 2019;9:8438 Nature Biomedical Engineering 2018;2:666-674 Science Translational Medicine 2017;9:eaal3226 Nature Biotechnology 2014;32:490-495

Responsibilities: Expertise in one or more of the following areas is desired but not required: engineering, optics (microscopy), molecular sensing, extracellular vesicles, neuroscience, Alzheimer’s diseases, cancers, cell biology, computer science (deep learning) or relevant areas. The ideal candidate will have interest in the development of new molecular diagnostic technologies and their applications in translational medicine.

Requirements: We seek motivated and creative individuals with a Ph.D. or M.D./Ph.D. degree. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Hyungsoon Im (im.hyungsoon@mgh.harvard.edu), Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Artificial intelligence, deep learning, computer science

Full/Part Time: Full Time

Investigator: Im, Hyungsoon

Date Posted: 2020-05-07

Description: A postdoctoral research position is available in the laboratory of Dr. Hyungsoon Im in the Center for Systems Biology (CSB) at the Massachusetts General Hospital (MGH), Harvard Medical School. We are interested in candidates with research background in artificial intelligence, deep learning, computer science, and relevant areas. We have active projects developing and applying AI algorithms for medical and microscopic imaging as well as their clinical translation.

Responsibilities: Expertise in one or more of the following areas is desired but not required: computer science, bioinformatics, engineering or relevant areas. The ideal candidate will have interest in the development of new deep-learning algorithms based on medical data and their applications in translational medicine.

Requirements: We seek motivated and creative individuals with a Ph.D. or M.D./Ph.D. degree. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Hyungsoon Im (im.hyungsoon@mgh.harvard.edu), Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Cancer genetics and tumor evolution

Full/Part Time: Full Time

Investigator: Naxerova, Kamila

Date Posted: 2020-01-28

Description: Two postdoctoral positions in cancer genetics are available in the Naxerova laboratory at the Center for Systems Biology at Massachusetts General Hospital and Harvard Medical School. The Naxerova lab studies the evolutionary history of cancer, using a blend of high-throughput experimental and computational approaches. We are interested in understanding how processes of mutation and selection in normal (stem) cells set the stage for cancer evolution. Once a tumor develops, how does tissue-specific selection shape the cancer genome? How can we take advantage of genetic intra-tumor heterogeneity to gain insights into the life history of a cancer? A particular interest of the lab is metastasis evolution. Do metastases arise from distinct clones with special, genetically encoded properties or do they represent random samples of the primary tumor? Do all metastases arise independently from the primary tumor, or do they give rise to each other? Does metastatic spread happen early or late in tumor development? Perhaps most importantly, is there a correlation between the evolutionary history of metastases and clinical outcomes? These questions are difficult to study in humans because it is challenging to reconstruct occult events that happened years before diagnosis. We are developing and applying new methods for lineage tracing in human cancer, with the ultimate goal of understanding a tumor’s entire evolution from the founder cell to lethal systemic disease. We have exciting new projects in the works and are looking for two postdoctoral fellows to join the team. Both experimentally and computationally inclined candidates are encouraged to apply. We are implementing experimental methods that generate large amounts of complex data and can thus offer fertile playing grounds to both experimentalists and bioinformaticians. The ideal candidate should be interested in doing some amount of both. To apply, please send a brief (less than 1 page) statement describing your interest in cancer genetics and your CV to Kamila Naxerova (naxerova.kamila@mgh.harvard.edu). Please check out the lab website csb.mgh.harvard.edu/naxerova for more information about publications and current lab members. We are a friendly, motivated team that is looking forward to hearing from you! The Center for Systems Biology (CSB), a multidisciplinary thematic center at Massachusetts General Hospital and Harvard Medical School, houses a vibrant scientific community united by its interest in integrative, quantitative biology and translational medicine. CSB and the larger Harvard community in which it is embedded offer near limitless opportunities for education and interdisciplinary collaboration. MGH offers excellent benefits to all employees and is an equal opportunity employer.

Requirements: There are no specific requirements for the job – we can teach you all the specifics here – but you should really burn for cancer genetics, enjoy grappling with difficult problems, be friendly and collegial, and have a track record in academic science that shows your commitment to this line of work.

Position: Postdoctoral Research Fellow

Research Area: Molecular profiling of cancer cells and microscopy

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2019-12-12

Description: The lab of Ralph Weissleder in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School invite applications for Postdoctoral Research Fellow positions. One or two positions are available in molecular profiling of cancer cells (see Sci Transl Med. 2014;6(219):219ra9). The ideal candidate should have a background in microfluidics, optics (microscopy), protein/DNA diagnostics, and cell biology, with expertise in system implementation and benchwork. The Center (csb.mgh.harvard.edu) has a diverse faculty with backgrounds in engineering, chemistry, biology, physics, and medicine, and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work. Research fellows are encouraged to write their own grants, following the training period, to launch their independent research.

Requirements: A Ph.D., M.D./Ph.D. or M.D. and permanent residency is required. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Synthetic chemistry

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2019-12-12

Description: The Weissleder lab in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School invites applications for Postdoctoral Research Fellow positions. One position is available in chemical synthesis of small molecules and bioconjugation. The Center has a diverse faculty with backgrounds in chemistry, biology, physics, engineering and medicine, and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work.

Requirements: A Ph.D., M.D./Ph.D. or M.D. and permanent residency is required. The ideal candidate has an extensive synthetic background and track record in chemical syntheses and analyses. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Biomedical engineering

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2019-12-12

Description: The lab of Ralph Weissleder (https://csb.mgh.harvard.edu/weissleder) in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School invites applications for Postdoctoral Research Fellow positions. Several positions are available in bioengineering, chemistry, imaging and/or cancer biology. Ideal candidates should have a strong academic background, US training and prior publications. The Center has a diverse faculty and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work. Research fellows are encouraged to write their own grants, following the training period, to launch their independent research.

Requirements: A Ph.D., or M.D./Ph.D. and permanent residency is required. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Neuroinflammation

Full/Part Time: Full Time

Investigator: Chen, John

Date Posted: 2019-12-12

Description: We are looking for an enthusiastic and bright postdoctoral fellow to join a translational imaging laboratory studying neuroinflammation at the Massachusetts General Hospital. Our laboratory works on novel diagnostic and therapeutic agents to track and treat against inflammation in a variety of CNS disorders in preclinical models, and seek to apply the findings in clinical settings. Our work had been published in Science, PNAS, Brain, JCI, and Radiology.

Responsibilities: Qualified candidates should email their CV and 3 references to John Chen, MD, PhD (jwchen@mgh.harvard.edu).

Requirements: Ph.D. The ideal candidate should be within 3 years of a completed Ph.D. (or equivalent degree) in neuroscience, immunology, systems biology, or related fields.

Position: Postdoctoral Research Fellow

Research Area: Cardiovascular Imaging and Physiology / Advanced Microscopy

Full/Part Time: Full Time

Investigator: Aguirre, Aaron

Date Posted: 2019-12-12

Description: Postdoctoral research positions are available in the laboratory of Dr. Aaron Aguirre at the Massachusetts General Hospital (MGH). Our laboratory applies expertise from medicine, engineering, and biology to perform basic and translational investigations of cardiovascular disease. The lab is a part of the Wellman Center for Photomedicine and the Center for Systems Biology at MGH, and we are closely affiliated with the MGH Cardiovascular Research Center. Recent work in the lab includes the development and use of cardiac intravital microscopy to study pathologic mechanisms of heart disease at cellular resolution in animal models. Thematic areas in the lab currently include 1) investigation of the remodeling and regulation of the coronary microcirculation in heart failure, 2) mapping of cardiac arrhythmia at the cellular scale using optical approaches, and 3) novel diagnostics for acute decompensated heart failure and circulatory shock. 

Responsibilities: Expertise in one or more of the following areas is desired but not absolutely required: cardiovascular physiology and imaging, biomedical image / signal processing, advanced optical microscopy (e.g. multiphoton microscopy, optical coherence tomography), ultrasound imaging, or quantitative cardiovascular biology. The ideal candidate will have interest in both the development of new imaging technologies and in the application of these methods to studying heart disease. Work with animal models is required. The candidate should have good written and oral communication skills and enjoy working in a collaborative, multidisciplinary environment.

Requirements: We seek motivated and creative individuals with a Ph.D. or M.D./Ph.D. degree and a passion for studying cardiovascular disease.  

Position: Research Technician II

Research Area: Computational Biology

Full/Part Time: Full Time

Investigator: Naxerova, Kamila

Date Posted: 2019-12-12

Description: A research technician or data analyst position is available in the Nahrendorf and Naxerova laboratories at the Center for Systems Biology at Massachusetts General Hospital and Harvard Medical School. If you are a motivated scientist with a Bachelor’s or Master’s degree in computational biology, bioinformatics, statistics or related relevant fields, and you want to be part of a dynamic, friendly team that produces and analyzes a large amount of complex data (genotyping data, DNA and RNA sequencing data, single cell sequencing data), please consider applying! We have a multitude of interesting projects in cancer genetics and cardiovascular disease research that will provide a rich playing ground for a person who enjoys thinking about data and its (biological) implications. We are looking for somebody who will actively be engaged in the research and take responsibility for their projects. This is not a job in which you will be told what to do step by step. After a thorough training phase, you will work independently and be able to realize your own ideas. You will be embedded into a great research team with lots of support, both from the biological as well as from the bioinformatics side. Recent graduates who are looking to earn a few years of research experience before applying to graduate school are particularly welcome. Please review these websites to learn more about our research: https://csb.mgh.harvard.edu/naxerova https://csb.mgh.harvard.edu/nahrendorf The Center for Systems Biology (CSB), a multidisciplinary thematic center at Massachusetts General Hospital and Harvard Medical School, houses a vibrant scientific community united by its interest in integrative, quantitative biology and translational medicine. MGH offers excellent benefits to all employees and is an equal opportunity employer. To apply, please send your CV to Kamila Naxerova (naxerova.kamila@mgh.harvard.edu).

Requirements: Bachelor’s or Master’s degree in computational biology

Send your application to (please specify position): Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114