Investigator / Platform Research Area Position
Weissleder, Ralph Computational cell analysis Postdoctoral Research Fellow
Weissleder, Ralph Exosome analysis Postdoctoral Research Fellow
Weissleder, Ralph Synthetic chemistry Postdoctoral Research Fellow
Weissleder, Ralph Single cell profiling of the tumor microenvironment Postdoctoral Research Fellow
Weissleder, Ralph Cancer Biology Postdoctoral Research Fellow
Hwang, William Spatial and Systems Oncology Research Technician
Higgins, John Mechanistic Mathematical Modeling of Human Disease Processes with Clinical Data Postdoctoral Research Fellow
Training Faculty Cancer research through innovative systems approaches T32 Postdoctoral fellow
More information:

Position: Postdoctoral Research Fellow

Research Area: Mechanistic Mathematical Modeling of Human Disease Processes with Clinical Data

Full/Part Time: Full Time

Investigator: Higgins, John

Date Posted: 2023-03-13

Description: A post-doctoral research position is available in the laboratory of John Higgins, MD, located in the Massachusetts General Hospital Center for Systems Biology and Department of Pathology and the Harvard Medical School Department of Systems Biology. Interested individuals should provide a CV and a cover letter describing past research experience, future research interests, career goals, and contact information for three references. Contact: John Higgins (john_higgins@hms.harvard.edu, https://sysbio.med.harvard.edu/john-higgins)

Requirements: Qualified applicants will have extensive knowledge of and interest in human pathophysiology and mathematical modeling including dynamical systems, statistical analysis, computational methods, and good software engineering practices. For example, strong candidates would be able to compare and contrast the following: hemostasis and thrombosis, ODE and PDE, lymphocyte and myelocyte, linear regression and conditional expectation. Applicants should have a Ph.D. and/or M.D. degree or be in their final year of their doctoral studies and at least a strong undergraduate background in math, computer science, or engineering.

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Position: Postdoctoral Research Fellow

Research Area: Cancer Biology

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2023-02-06

Description: The Center for Systems Biology (CSB) at Massachusetts General Hospital (MGH) seeks applications for a T32 postdoctoral fellows interested in cancer biology. We seek outstanding individuals with PhD, MD, or MD-PhD degrees who are US residents. Areas of interest include spatial proteomics, single cell analysis, exosomes, immunology, chemistry, imaging, as well as mathematical and engineering approaches directed toward understanding of tissue organization and disease progression.

Requirements: Interested candidates are invited to submit application materials. Each application must include one PDF file with: i) a cover letter indicating research plan including a statement of impact, ii) a curriculum vitae and iii) three references.

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Position: Postdoctoral Research Fellow

Research Area: Single cell profiling of the tumor microenvironment

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2022-10-17

Description: The lab of Ralph Weissleder in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School has a number of openings for Postdoctoral Research Fellows. The ideal candidate should have a background in microscopy, cell culture and immunology with expertise in system implementation and benchwork. The Center (csb.mgh.harvard.edu) has a diverse faculty with backgrounds in engineering, chemistry, biology, physics, and medicine, and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work. Research fellows are encouraged to write their own grants, following the training period, to launch their independent research.

Requirements: A Ph.D., M.D./Ph.D. or M.D. and permanent residency is required. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Synthetic chemistry

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2022-10-17

Description: The Weissleder lab in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School invites applications for Postdoctoral Research Fellow positions. One position is available in chemical synthesis of small molecules and bioconjugation. The Center has a diverse faculty with backgrounds in chemistry, biology, physics, engineering and medicine, and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work.

Requirements: A Ph.D., M.D./Ph.D. or M.D. and permanent residency is required. The ideal candidate has an extensive synthetic background and track record in chemical syntheses and analyses. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114.

Position: Postdoctoral Research Fellow

Research Area: Exosome analysis

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2022-10-17

Description: The lab of Ralph Weissleder (https://csb.mgh.harvard.edu/weissleder) in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School invites applications for Postdoctoral Research Fellow positions. A position is available in single cell and exosome analysis. Ideal candidates should have a strong academic background, US training and prior publications. The Center has a diverse faculty and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work. Research fellows are encouraged to write their own grants, following the training period, to launch their independent research.

Requirements: A Ph.D., or M.D./Ph.D. and permanent residency is required. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan Sullivan.Serena@mgh.harvard.edu.

Position: Postdoctoral Research Fellow

Research Area: Computational cell analysis

Full/Part Time: Full Time

Investigator: Weissleder, Ralph

Date Posted: 2022-10-17

Description: The lab of Ralph Weissleder (https://csb.mgh.harvard.edu/weissleder) in the Center for Systems Biology at the Massachusetts General Hospital, Harvard Medical School invites applications for Postdoctoral Research Fellow positions. One position is available in computational single cell analysis, spatial profiling, temporal profiling and modeling. Ideal candidates should have a strong academic background, US training and prior publications. The Center has a diverse faculty and offers a lively and supportive environment in which to perform interdisciplinary science.

Responsibilities: We seek creative thinkers who take risks in defining and addressing important problems, and who use quantitative experimental, computational and/or theoretical approaches in their work. Research fellows are encouraged to write their own grants, following the training period, to launch their independent research.

Requirements: A Ph.D., or M.D./Ph.D. and permanent residency is required. To apply, please send your CV, a summary of your most significant research accomplishments (300 words) and the email addresses of three references to: Serena Sullivan Sullivan.Serena@mgh.harvard.edu.

Position: T32 Postdoctoral fellow

Research Area: Cancer research through innovative systems approaches

Full/Part Time: Full Time

Group: Training Faculty

Date Posted: 2022-10-17

Description: With our current faculty of 34 mentors, enhanced facilities, scope of supported research and past accomplishments, we offer an outstanding research environment for the next generation of clinicians and scientists to be trained in molecular imaging and systems analysis.

Requirements: These positions are restricted to US citizens and/or permanent residents.

Position: Research Technician

Research Area: Spatial and Systems Oncology

Full/Part Time: Full Time

Investigator: Hwang, William

Date Posted: 2022-10-11

Description: The Hwang Lab (Laboratory for Spatial and Systems Oncology) in the Center for Systems Biology, Center for Cancer Research, and Department of Radiation Oncology at Massachusetts General Hospital, Harvard Medical School (https://www.whwanglab.org/) is looking for an exceptional research technician who wants to work as an integral part of a fun, collegial team on solving big problems in spatial and systems oncology and with a principal investigator who prioritizes mentorship. Prior technicians have been co-first authors and co-authors on 3 or more high impact papers each, presented as lead authors at conferences, and gained admission to prestigious MD and PhD programs such as the Harvard-MIT Health Sciences and Technology program. This training experience is ideal for preparing candidates who are interested in pursuing subsequent PhD and/or MD training. The research technician will have an opportunity to work closely with Dr. Hwang and team members to elucidate mechanisms of therapeutic resistance in cancer, develop translatable biomarkers to track tumor remodeling during treatment, and/or investigate the interface of cancer with the nervous system. You will have the opportunity to develop and apply techniques in single-cell and spatial biology, imaging, genetic screens, and neuroscience to patient tumors and cutting-edge model systems of cancer (e.g., organoids, mouse models). The Hwang Lab works broadly on gastrointestinal malignancies with a particular focus on pancreatic cancer. Ideal candidates should have a strong interest in cancer biology and/or neuroscience, prior experience in laboratory biological research, motivated and willing to learn new techniques, thrive in both collaborative and independent situations, and highly organized. A 2-year commitment is preferred and if the candidate is interested, they may have the opportunity to lead or co-lead an independent project during their tenure.

Responsibilities: The research technician will design and execute experimental protocols in support of the diverse research efforts in the laboratory. Specific responsibilities and skills that will be developed through this role include but are not limited to leading edge spatial proteotranscriptomics, multiplexed confocal/immunofluorescence imaging, single-cell and -nucleus RNA-sequencing and multiomics, blood/plasma multiomics, advanced 2D and 3D cell culture techniques, molecular cloning/lentiviral transduction/CRISPR genetic engineering, mouse colony management, survival surgeries and orthotopic pancreatic transplants, dorsal root ganglion dissections and neuronal culture techniques, live cell imaging and neurite tracking, immunohistochemistry, Western blot, qPCR, drug screens, and flow cytometry. Prepares basic solutions and performs base-level procedures as assigned (i.e. – pipetting, cell and tissue culture, etc.) Maintains laboratory notebook Understands and applies basic scientific techniques Conducts analysis of results and may begin interpretation of results Sets up and prepares routine experiments as directed Prepares lab reagents, chemicals, instruments and equipment May perform independent literature searches Assists with organizing materials for publication or presentation A Research Technician II performs the duties of a Research Technician I (above) and may also: Execute protocols of non-routine experiments Assist the PI(s) with determining the most suitable methodology Perform basic design and modification of protocols Calculate, transcribe and analyze data Prepare and present reports Organize and summarize acquired data, using scientific and statistical techniques. Organize and/or draft material for the preparation of research papers, manuscripts and other documents for publication and/or presentation. Participate in the design of experiments or field work.

Requirements: A Bachelor’s degree is required before the anticipated start date, with prior laboratory experience in laboratory cancer biology and/or neuroscience preferred. This position is full time. To formally apply please go to, https://www.massgeneral.org/careers/apply and search for job ID# 3216413. In addition to this you may send your resume, short summary of prior academic/research experiences and career goals, and a list of personal/professional references to Serena Sullivan at sullivan.serena@mgh.harvard.edu and William Hwang, MD, PhD at whwang1@mgh.harvard.edu.

Send your application to (please specify position): Serena Sullivan (Sullivan.Serena@mgh.harvard.edu), CSB, Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114