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Battistone MA, Mendelsohn AC, Spallanzani RG, Allegretti AS, Liberman RN, Sesma J, Kalim S, Wall SM, Bonventre JV, Lazarowski ER, Brown D, Breton S
Pro-inflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice.
J Clin Invest. 2020;130(7):3734-3749 - PMID: 32287042 - PMCID: PMC7324186 - DOI: 10.1172/JCI134791
Cheung PW, Bouley R, Brown D
Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit.
Annu Rev Pharmacol Toxicol. 2020;60:175-194 - PMID: 31561739 - PMCID: PMC7334826 - DOI: 10.1146/annurev-pharmtox-010919-023654
Xiao X, Dev S, Canali S, Bayer A, Xu Y, Agarwal A, Wang CY, Babitt JL
Endothelial Bmp2 knockout exacerbates hemochromatosis in Hfe knockout mice but not Bmp6 knockout mice.
Hepatology. 2020;72(2):642-655 - PMID: 31778583 - PMCID: PMC7253321 - DOI: 10.1002/hep.31048
Wang CY, Xu Y, Traeger L, Dogan DY, Xiao X, Steinbicker AU, Babitt JL
Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
Blood. 2020;135(6):453-456 - PMID: 31800957 - PMCID: PMC7005366 - DOI: 10.1182/blood.2019002620
Brown CR, Gupta S, Qin J, Racie T, He G, Lentini S, Malone R, Yu M, Matsuda S, Shulga-Morskaya S, Nair AV, Theile CS, Schmidt K, Shahraz A, Goel V, Parmar RG, Zlatev I, Schlegel MK, Nair JK, Jayaraman M, Manoharan M, Brown D, Maier MA, Jadhav V
Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates.
Nucleic Acids Res. 2020;:ePub - PMID: 32808038 - DOI: 10.1093/nar/gkaa670
Bouley R, Yui N, Terlouw A, Cheung PW, Brown D
Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells.
Cells. 2020;9(4):ePub - PMID: 32340337 - PMCID: PMC7226349 - DOI: 10.3390/cells9041057
Castro MM, Kim B, Games PD, Hill E, Neves CA, SerrĂ£o JE, Breton S, Machado-Neves M
Distribution pattern of ZO-1 and claudins in the epididymis of vampire bats.
Tissue Barriers. 2020;:1779526 - PMID: 32552339 - DOI: 10.1080/21688370.2020.1779526
Kim B, Breton S
Androgens are essential for epithelial cell recovery after efferent duct ligation in the initial segment of the mouse epididymis.
Biol Reprod. 2020;102(1):76-83 - PMID: 31403160 - PMCID: PMC7334622 - DOI: 10.1093/biolre/ioz152