Li W, Jin WW, Tsuji K, Chen Y, Nomura N, Su L, Yui N, Arthur J, Cotecchia S, Păunescu TG, Brown D, Lu HAJ

Direct interaction of ezrin and AQP2 and its role in AQP2 trafficking.
J Cell Sci. 2017;130(17):2914-2925 - PMID: 28754689 - PMCID: PMC5612225 - DOI: 10.1242/jcs.204842

Mamuya FA, Xie D, Lei L, Huang M, Tsuji K, Capen DE, Yang B, Weissleder R, Păunescu TG, Lu HJ

Deletion of β-1 integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis.
Am J Physiol Renal Physiol. 2017;313(4):F1026-F1037 - PMID: 28701310 - PMCID: PMC5668581 - DOI: 10.1152/ajprenal.00038.2017

Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Lu HA, Brown D, Bouley R

EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
J Am Soc Nephrol. 2016;27(10):3105-3116 - PMID: 27694161 - PMCID: PMC5042667 - DOI: 10.1681/ASN.2015080903

Mamuya FA, Cano-Peñalver JL, Li WU, Rodriguez-Puyol D, Rodríguez-Puyol M, Brown D, de Frutos S, Lu HJ

ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway.
Am J Physiol Renal Physiol. 2016;311(6):F1346-F1357 - PMID: 27760768 - PMCID: PMC5210194 - DOI: 10.1152/ajprenal.00336.2016

Rice WL, Li W, Mamuya F, McKee M, Păunescu TG, Lu HA

Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture.
PLoS ONE. 2015;10(7):e0131719 - PMID: 26147297 - PMCID: PMC4493001 - DOI: 10.1371/journal.pone.0131719

Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ

Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells.
Am J Physiol Renal Physiol. 2015;309(8):F673-9 - PMID: 26290367 - PMCID: PMC4609919 - DOI: 10.1152/ajprenal.00152.2015

Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D

High throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration.
Am J Physiol Cell Physiol. 2014;307(7):C597-605 - PMID: 24944200 - PMCID: PMC4187055 - DOI: 10.1152/ajpcell.00154.2014

Brown D, Jenny Lu HA

Aquaporin-2 Inhibitors: Fishing in the Chemical Pool.
J Am Soc Nephrol. 2013;24(5):685-6 - PMID: 23599384 - DOI: 10.1681/ASN.2013030243

Huang J, McKee M, Huang HD, Xiang A, Davidson AJ, Lu HA

A zebrafish model of conditional targeted podocyte ablation and regeneration.
Kidney Int. 2013;83(6):1193-200 - PMID: 23466998 - PMCID: PMC3672345 - DOI: 10.1038/ki.2013.6

Paunescu TG, Lu HA, Russo LM, Pastor-Soler NM, McKee M, McLaughlin MM, Bartlett BE, Breton S, Brown D

Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells.
Am J Physiol Renal Physiol. 2013;305(12):F1783-F1795 - PMID: 24133120 - PMCID: PMC3882446 - DOI: 10.1152/ajprenal.00622.2012

Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA

Aquaporin 2 Promotes Cell Migration and Epithelial Morphogenesis.
J Am Soc Nephrol. 2012;23(9):1506-17 - PMID: 22859853 - PMCID: PMC3431417 - DOI: 10.1681/ASN.2012010079

Rice WL, Zhang Y, Chen Y, Matsuzaki T, Brown D, Lu HA

Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells.
PLoS ONE. 2012;7(2):e32843 - PMID: 22403603 - PMCID: PMC3293519 - DOI: 10.1371/journal.pone.0032843

Yui N, Lu HA, Chen Y, Nomura N, Bouley R, Brown D

Basolateral targeting and microtubule dependent transcytosis of the aquaporin-2 water channel.
Am J Physiol Cell Physiol. 2012;304(1):C38-48 - PMID: 23015545 - PMCID: PMC3543574 - DOI: 10.1152/ajpcell.00109.2012

Brown D, Bouley R, Paunescu TG, Breton S, Lu HA

New insights into the dynamic regulation of water and acid/base balance by renal epithelial cells.
Am J Physiol Cell Physiol. 2012;302(10):C1421-33 - PMID: 22460710 - PMCID: PMC3362000 - DOI: 10.1152/ajpcell.00085.2012

Li W, Zhang Y, Bouley R, Chen Y, Matsuzaki T, Nunes P, Hasler U, Brown D, Lu HA

Simvastatin Enhances Aquaporin 2 Surface Expression and Urinary Concentration in Vasopressin Deficient Brattleboro Rats through Modulation of Rho GTPase.
Am J Physiol Renal Physiol. 2011;301(2):F309-18 - PMID: 21511701 - PMCID: PMC3154588 - DOI: 10.1152/ajprenal.00001.2011

Yui N, Lu HJ, Bouley R, Brown D

AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells.
Biol Open. 2011;1(2):101-8 - PMID: 23213402 - PMCID: PMC3507199 - DOI: 10.1242/bio.2011042

Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D

Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration.
J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035 - DOI: 10.1681/ASN.2009121267

Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF

Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression.
Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332 - DOI: 10.1152/ajprenal.90762.2008

Hasler U, Nunes P, Bouley R, Lu HA, Matsuzaki T, Brown D

Acute hypertonicity alters aquaporin-2 trafficking and induces a MAP kinase-dependent accumulation at the plasma membrane of renal epithelial cells.
J Biol Chem. 2008;283(39):26643-61 - PMID: 18664568 - PMCID: PMC2546545 - DOI: 10.1074/jbc.M801071200

Brown D, Hasler U, Nunes P, Bouley R, Lu H

Phosphorylation events and the modulation of aquaporin 2 cell surface expression.
Curr Opin Nephrol Hypertens. 2008;17(5):491-8 - PMID: 18695390 - PMCID: PMC3774073 - DOI: 10.1097/MNH.0b013e3283094eb1

Nunes P, Hasler U, McKee M, Lu HA, Bouley R, Brown D

A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2 (AQP2).
Am J Physiol Cell Physiol. 2008;295(6):C1476-87 - PMID: 18799651 - PMCID: PMC2603565 - DOI: 10.1152/ajpcell.00344.2008

Lu HA, Matsuzaki T, Bouley R, Hasler U, Qin Q, Brown D

The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.
Am J Physiol Renal Physiol. 2008;295(1):F290-4 - PMID: 18434387 - PMCID: PMC2494506 - DOI: 10.1152/ajprenal.00072.2008

Bouley R, Hasler U, Lu HA, Nunes P, Brown D

Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus.
Semin Nephrol. 2008;28:266-78 - PMID: 18519087 - PMCID: PMC2494582 - DOI: 10.1016/j.semnephrol.2008.03.010

Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D

Heat shock protein 70 interacts with aquaporin-2 (AQP2) and regulates its trafficking.
J Biol Chem. 2007;282(39):28721-32 - PMID: 17636261 - DOI: 10.1074/jbc.M611101200

Paunescu TG, Da Silva N, Russo LM, McKee M, Lu HA, Breton S, Brown D

Association Of Soluble Adenylyl Cyclase (sAC) With The V-ATPase In Renal Epithelial Cells.
Am J Physiol Renal Physiol. 2007;294(1):F130-8 - PMID: 17959750 - DOI: 10.1152/ajprenal.00406.2007

Yi X, Bouley R, Lin HY, Bechoua S, Sun TX, Del Re E, Shioda T, Raychowdhury MK, Lu HA, Abou-Samra AB, Brown D, Ausiello DA

Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.
Am J Physiol Renal Physiol. 2007;292(5):F1303-13 - PMID: 17287200 - DOI: 10.1152/ajprenal.00441.2005
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