Clinical Discovery Program
The purpose of the Clinical Discovery Program is to rapidly translate and test novel diagnostic and therapeutic approaches from bench to bedside. This Program focuses primarily on technologies previously developed at CSB but also applies other new technologies as they are related to human biology. The primary fields of interest are currently in cancer dx, clinical imaging and systems analyses. Investigators in this program are practicing clinician scientists from Massachusetts General Hospital and collaborators from other Harvard Medical School teaching hospitals. The program is primarily funded through grants from NIH.
Recent Publications
Lin EW, Pathak P, O'Shea A, Awasthi B, Phillips IE, Kocher JR, Song Y, Raabe MJ, Xu KH, Patel BK, Lester N, Bae JW, Zhang ML, Nieman LT, Blaszkowsky LS, Walsh EP, Parikh AR, Hansen A, Caufield J, Newbert G, Asombang AW, Casey B, Cohen J, Jacobson BC, Krishnan K, Uppot R, Weissleder R, Horick NK, Hwang WL, Harisinghani MG, Ting DT, Weekes CD
Therapeutic Targeting of Epithelial Mesenchymal Cellular Plasticity in Pancreatic Cancer. Clin Cancer Res. 2025;:ePub - PMID: 41364739 - DOI: 10.1158/1078-0432.CCR-25-2052Timms L, Zhou T, Qiao J, Gharagouzloo C, Mishra V, Lahoud RM, Chen JW, Harisinghani M, Sridhar S
Super High Contrast USPIO-Enhanced Cerebrovascular Angiography Using Ultrashort Time-to-Echo MRI. Int J Biomed Imaging. 2024;2024:9763364 - PMID: 38644981 - PMCID: PMC11032209 - DOI: 10.1155/2024/9763364- More publications ...
News
"Observing The Development Of Type 1 Diabetes" - CSB publication has been highlighted on Snapshot of Science at Mass General
Mukesh G. Harisinghani, MD, has been promoted to Professor of Radiology, Harvard Medical School. Congratulations Mukesh!
Sandeep Hedgire, MD receives the Cum Laude award for his education exhibit at the 98th Scientific Assembly and Annual Meeting of the Radiological Society of North America.
New Boston Museum of Science's Virtual Exhibit features work of Drs. Weissleder and Harisinghani on the design of a clinical trial to determine how iron-oxide nanoparticles could enhance a diagnostic image produced by an MRI machine to the extent that the spread of cancer could be accurately assessed.