Brain motor and fear circuits regulate leukocytes during acute stress.
Nature. 2022;607(7919):578-584 - PMID: 35636458 - PMCID: PMC9798885 - DOI: 10.1038/s41586-022-04890-z
Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes
Nat Biotechnol. 2022;40(11):1654-1662 - PMID: 35654978 - PMCID: PMC9669087 - DOI: 10.1038/s41587-022-01339-6
Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma.
Enhanced competition at the nano-bio interface enables comprehensive characterization of protein corona dynamics and deep coverage of proteomes.
Adv Mater. 2022;34(44):e2206008 - PMID: 35986672 - DOI: 10.1002/adma.202206008
Multiplexed imaging in oncology
Nat Biomed Eng. 2022;6(5):527-540 - PMID: 35624151 - DOI: 10.1038/s41551-022-00891-5
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis.
Nat Neurosci. 2022;25(5):567-576 - PMID: 35501382 - PMCID: PMC9081225 - DOI: 10.1038/s41593-022-01060-2
Leveraging technology to address current and future world issues.
Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles.
In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy
Adv Sci (Weinh). 2022;9(24):e2200064 - PMID: 35750648 - PMCID: PMC9405492 - DOI: 10.1002/advs.202200064
Integrated Analytical System for Clinical Single-Cell Analysis
Adv Sci (Weinh). 2022;9(20):e2200415 - PMID: 35508767 - PMCID: PMC9284190 - DOI: 10.1002/advs.202200415
Multielectrode Spectroscopy Enables Rapid and Sensitive Molecular Profiling of Extracellular Vesicles.
ACS Cent Sci. 2022;8(1):110-117 - PMID: 35111901 - PMCID: PMC8802188 - DOI: 10.1021/acscentsci.1c01193
Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy.
Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer.
Deciphering albumin-directed drug delivery by imaging.
Adv Drug Deliv Rev. 2022;185:114237 - PMID: 35364124 - PMCID: PMC9117484 - DOI: 10.1016/j.addr.2022.114237
Single extracellular vesicle analysis for early cancer detection
Trends in Molecular Medicine. 2022;28(8):681-692 - PMID: 35624008 - PMCID: PMC9339504 - DOI: 10.1016/j.molmed.2022.05.003
Glioblastoma-derived extracellular vesicle subpopulations following 5-aminolevulinic acid treatment bear diagnostic implications.
J Extracell Vesicles. 2022;11(11):e12278 - PMID: 36404434 - PMCID: PMC9676504 - DOI: 10.1002/jev2.12278
Physisorption of Affinity Ligands Facilitates Extracellular Vesicle Detection with Low Non-Specific Binding to Plasmonic Gold Substrates.
ACS Appl Mater Interfaces. 2022;:ePub - PMID: 35653580 - PMCID: PMC9715849 - DOI: 10.1021/acsami.2c07317
Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities.
Cellular point-of-care diagnostics using an inexpensive layer-stack microfluidic device.
Multiplexed single-cell analysis of FNA allows accurate diagnosis of salivary gland tumors.
Cancer Cytopathol. 2022;130(8):581-594 - PMID: 35666645 - PMCID: PMC9542730 - DOI: 10.1002/cncy.22594
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release.
Bioconjug Chem. 2022;33(8):1474-1484 - PMID: 35833631 - PMCID: PMC9390333 - DOI: 10.1021/acs.bioconjchem.2c00174
Cycling, Fasting, Fishing, and Other Things: The Emerging World of Biocompatible Chemistries
Adv Biol (Weinh). 2022;7(1):e2200178 - PMID: 36047616 - PMCID: PMC10228596 - DOI: 10.1002/adbi.202200178
TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells
Adv Biol (Weinh). 2022;6(8):e2200030 - PMID: 35675910 - PMCID: PMC9398996 - DOI: 10.1002/adbi.202200030
Computational Optics for Point-of-Care Breast Cancer Profiling.
Methods Mol Biol. 2022;2393:153-162 - PMID: 34837178 - PMCID: PMC9283060 - DOI: 10.1007/978-1-0716-1803-5_8
Multiplexed analysis of a single EV (MASEV) reveals unique biomarker composition with diagnostic impact
bioRxiv. 2022;:ePub - DOI: 10.1101/2022.06.17.496607
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