Sort by:

Shao H, Im H, Castro CM, Breakefield X, Weissleder R, Lee H

New Technologies for Analysis of Extracellular Vesicles.
Chem Rev. 2018;118(4):1917-1950 - PMID: 29384376 - PMCID: PMC6029891 - DOI: 10.1021/acs.chemrev.7b00534

Garris CS*, Arlauckas SP*, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
Immunity. 2018;49:1-14 - PMID: 30552023 - PMCID: PMC6301092 - DOI: 10.1016/j.immuni.2018.09.024

Im H, Pathania D, McFarland PJ, Sohani AR, Degani I, Allen M, Coble M, Kilcoyne A, Hong S, Rohrer L, Abramson JS, Dryden-Peterson S, Fexon L, Pivovarov M, Chabner B, Lee H, Castro CM, Weissleder R

Design and clinical validation of a point-of-care device for the diagnosis of lymphoma via contrast- enhanced microholography and machine learning
Nat Biomed Eng. 2018;2(9):666-674 - PMID: 30555750 - PMCID: PMC6291220 - DOI: 10.1038/s41551-018-0265-3

Rodell CB, Arlauckas SP, Cuccarese MF, Garris CS, Li R, Ahmed MS, Kohler RH, Pittet MJ, Weissleder R

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.
Nat Biomed Eng. 2018;2:578-588 - PMID: 31015631 - PMCID: PMC6192054 - DOI: 10.1038/s41551-018-0236-8

Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Santos Masson G, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration
Nat Neurosci. 2018;21(9):1209-1217 - PMID: 30150661 - PMCID: PMC6148759 - DOI: 10.1038/s41593-018-0213-2

Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca A, Breakefield XO, Lee H, Weissleder R

Multiplexed Profiling of Single Extracellular Vesicles.
ACS Nano. 2018;12(1):494-503 - PMID: 29286635 - PMCID: PMC5898240 - DOI: 10.1021/acsnano.7b07060

Miller MA, Mikula H, Luthria G, Li R, Kronister S, Prytyskach M, Kohler RH, Mitchison T, Weissleder R

Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation.
ACS Nano. 2018;12(12):12814-12826 - PMID: 30550257 - PMCID: PMC6307086 - DOI: 10.1021/acsnano.8b07954

Kim HY, Li R, Ng TSC, Courties G, Rodell CB, Prytyskach M, Kohler RH, Pittet M, Nahrendorf M, Weissleder R, Miller MA

Quantitative Imaging of Tumor Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin.
ACS Nano. 2018;12(12):12015-12029 - PMID: 30508377 - PMCID: PMC6482841 - DOI: 10.1021/acsnano.8b04338

Min J, Im H, Allen M, McFarland PJ, Degani I, Yu H, Normandin E, Pathania D, Patel J, Castro CM, Weissleder R, Lee H

Computational Optics Enables Breast Cancer Profiling in Point-Of-Care Settings.
ACS Nano. 2018;12(9):9081-9090 - PMID: 30113824 - PMCID: PMC6519708 - DOI: 10.1021/acsnano.8b03029

Min J, Nothing M, Coble B, Zheng H, Park J, Im H, Weber GF, Castro CM, Swirski FK, Weissleder R, Lee H

Integrated Biosensor for Rapid and Point-Of-Care Sepsis Diagnosis.
ACS Nano. 2018;12(4):3378-3384 - PMID: 29533646 - PMCID: PMC6019292 - DOI: 10.1021/acsnano.7b08965

Hulsmans M, Aguirre AD, Bonner M, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M

Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse
Circ Res. 2018;123(11):1208-1219 - PMID: 30571465 - PMCID: PMC6309285 - DOI: 10.1161/CIRCRESAHA.118.313429

Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz GR, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson FE, Jung Y, Désogère P, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress.
Circ Res. 2018;123(4):415-427 - PMID: 29980569 - PMCID: PMC6202141 - DOI: 10.1161/CIRCRESAHA.118.313302

Carlson J, Mikula H, Weissleder R

Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage.
J Am Chem Soc. 2018;140(10):3603-3612 - PMID: 29384666 - PMCID: PMC5857921 - DOI: 10.1021/jacs.7b11217

Giedt RJ, Pathania D, Carlson JCT, McFarland PJ, Del Castillo AF, Juric D, Weissleder R

Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens
Nat Commun. 2018;9(1):4550 - PMID: 30382095 - PMCID: PMC6208406 - DOI: 10.1038/s41467-018-07002-6

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M

Cardiac macrophages promote diastolic dysfunction.
J Exp Med. 2018;215(2):423-440 - PMID: 29339450 - PMCID: PMC5789416 - DOI: 10.1084/jem.20171274

Ricklefs FL, Alayo Q, Krenzlin H, Mahmoud AB, Speranza MC, Nakashima H, Hayes JL, Lee K, Balaj L, Passaro C, Rooj AK, Krasemann S, Carter BS, Chen CC, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield XO, Godlewski J, Westphal M, Lamszus K, Freeman GJ, Bronisz A, Lawler SE, Chiocca EA

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles.
Sci Adv. 2018;4(3):eaar2766 - PMID: 29532035 - PMCID: PMC5842038 - DOI: 10.1126/sciadv.aar2766

Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R

Fluorescence anisotropy imaging in drug discovery.
Adv Drug Deliv Rev. 2018;151-152:262-288 - PMID: 29410158 - PMCID: PMC6072632 - DOI: 10.1016/j.addr.2018.01.019

Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ

Site occupancy calibration of taxane pharmacology in live cells and tissues
Proc Natl Acad Sci U S A. 2018;115(48):E11406-E11414 - PMID: 30429313 - PMCID: PMC6275538 - DOI: 10.1073/pnas.1800047115

Magnuson AM, Kiner E, Ergun A, Park JS, Asinovski N, Ortiz-Lopez A, Kilcoyne A, Paoluzzi-Tomada E, Weissleder R, Mathis D, Benoist C

Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types.
Proc Natl Acad Sci U S A. 2018;115(45):E10672-E10681 - PMID: 30348759 - PMCID: PMC6233093 - DOI: 10.1073/pnas.1810580115

Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M

Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Proc Natl Acad Sci U S A. 2018;115(15):3912-3917 - PMID: 29581255 - PMCID: PMC5899492 - DOI: 10.1073/pnas.1801524115

Arlauckas SP*, Garren SB*, Garris CS, Kohler RH, Oh J, Pittet MJ, Weissleder R

Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages
Theranostics. 2018;8(21):5842-5854 - PMID: 30613266 - PMCID: PMC6299430 - DOI: 10.7150/thno.26888

Huber S, Min C, Staat C, Oh J, Castro CM, Haase A, Weissleder R, Gleich B, Lee H

Multichannel digital heteronuclear magnetic resonance biosensor.
Biosens Bioelectron. 2018;126:240-248 - PMID: 30445298 - PMCID: PMC6483068 - DOI: 10.1016/j.bios.2018.10.052

Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE

Preclinical investigation of gene-mediated cytotoxic immunotherapy and checkpoint blockade in glioblastoma.
Neuro Oncol. 2018;20(2):225-235 - PMID: 29016938 - PMCID: PMC5777502 - DOI: 10.1093/neuonc/nox139

Pittet MJ, Garris CS, Arlauckas SP, Weissleder R

Recording the wild lives of immune cells.
Sci Immunol. 2018;3(27):ePub - PMID: 30194240 - PMCID: PMC6771424 - DOI: 10.1126/sciimmunol.aaq0491

Oh J, Magnuson A, Benoist C, Pittet MJ, Weissleder R

Age-related tumor growth in mice is related to integrin α 4 in CD8+ T cells
JCI Insight. 2018;3(21):ePub - PMID: 30385729 - PMCID: PMC6238736 - DOI: 10.1172/jci.insight.122961

Schoenberg SO, Attenberger UI, Solomon SB, Weissleder R

Developing a Roadmap for Interventional Oncology.
Oncologist. 2018;23(10):1162-1170 - PMID: 29959284 - PMCID: PMC6263130 - DOI: 10.1634/theoncologist.2017-0654

Kim SJ*, Wang C*, Zhao B, Im H, Min J, Choi HJ, Tadros J, Choi NR, Castro CM, Weissleder R, Lee H, Lee K

Deep transfer learning-based hologram classification for molecular diagnostics.
Sci Rep. 2018;8(1):17003 - PMID: 30451953 - PMCID: PMC6242900 - DOI: 10.1038/s41598-018-35274-x

Aganj I, Harisinghani MG, Weissleder R, Fischl B

Unsupervised medical image segmentation based on the local center of mass
Sci Rep. 2018;8:13012 - PMID: 30158534 - PMCID: PMC6115387 - DOI: 10.1038/s41598-018-31333-5

Sahin A, Sanchez C, Bullain S, Waterman P, Weissleder R, Carter BS

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma.
PLoS ONE. 2018;13(7):e0199414 - PMID: 29975720 - PMCID: PMC6033533 - DOI: 10.1371/journal.pone.0199414

Vinegoni C, Feruglio PF, Weissleder R

High dynamic range fluorescence imaging.
IEEE J Sel Top Quantum Electron. 2018;25(1):ePub - PMID: 31598059 - PMCID: PMC6785194 - DOI: 10.1109/JSTQE.2018.2881608

Vinegoni C, Feruglio PF, Weissleder R

High dynamic range fluorescence imaging.
IEEE J Sel Top Quantum Electron. 2018;25(1):ePub - PMID: 31598059 - PMCID: PMC6785194 - DOI: 10.1109/JSTQE.2018.2881608

Lin HY, Yang KS, Curley C, Lee H, Welch MW, Wolpin BM, Weissleder R, Im H, Castro C

Bead Enhancement of EV Analysis
bioRxiv. 2018;:ePub - DOI: 10.1101/269423
32 CSV