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Weissleder R, Lee H
Automated molecular-image cytometry and analysis in modern oncology
Nature Review Materials. 2020;:ePub - DOI: 10.1038/s41578-020-0180-6
Herrmann K, Schwaiger M, Lewis JS, Solomon SB, McNeil BJ, Baumann M, Gambhir SS, Hricak H, Weissleder R
Radiotheranostics: a roadmap for future development
Lancet Oncol. 2020;21(3):e146–56 - PMID: 32135118 - PMCID: PMC7367151 - DOI: 10.1016/S1470-2045(19)30821-6 - Cover
Yang KS, Ciprani D, O'Shea A, Liss A, Yang R, Fletcher-Mercaldo S, Mino-Kenudson M, Castillo CF, Weissleder R
Extracellular Vesicle Analysis Allows for Identification of Invasive IPMN
Gastroenterology. 2020;160(4):1345-1358.e11 - PMID: 33301777 - PMCID: PMC7956058 - DOI: 10.1053/j.gastro.2020.11.046
Weissleder R, Pittet MJ
The expanding landscape of inflammatory cells affecting cancer therapy
Nat Biomed Eng. 2020;4(5):489-498 - PMID: 32203281 - PMCID: PMC7405944 - DOI: 10.1038/s41551-020-0524-y
Cremer S, Schloss MJ, Vinegoni C, Foy BH, Zhang S, Rohde D, Hulsmans M, Fumene Feruglio P, Schmidt S, Wojtkiewicz G, Higgins JM, Weissleder R, Swirski FK, Nahrendorf M
Diminished Reactive Hematopoiesis and Cardiac Inflammation in a Mouse Model of Recurrent Myocardial Infarction.
J Am Coll Cardiol. 2020;75(8):901-915 - PMID: 32130926 - PMCID: PMC7254576 - DOI: 10.1016/j.jacc.2019.12.056
Luthria G, Li R, Wang S, Prytyskach M, Kohler RH, Lauffenburger DA, Mitchison TJ, Weissleder R, Miller MA
In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells
Nat Commun. 2020;11:3521 - PMID: 32665556 - PMCID: PMC7360550 - DOI: 10.1038/s41467-020-17147-y
Wang Y, Cao T, Ko J, Shen Y, Zong W, Sheng K, Cao W, Sun S, Cai L, Zhou YL, Zhang XX, Zong C, Weissleder R, Weitz D
Dissolvable Polyacrylamide Beads for High-Throughput Droplet DNA Barcoding.
Adv Sci. 2020;7(8):1903463 - PMID: 32328429 - PMCID: PMC7175265 - DOI: 10.1002/advs.201903463
Min J*, Chin LK*, Oh J, Landeros C, Vinegoni C, Lee J, Lee SJ, Park JY, Liu AQ, Castro CM, Lee H, Im H, Weissleder R
CytoPAN—Portable cellular analyses for rapid point-of-care cancer diagnosis
Sci Transl Med. 2020;12:eaaz9746 - PMID: 32759277 - PMCID: PMC8217912 - DOI: 10.1126/scitranslmed.aaz9746
Weissleder R, Lee H, Ko J, Pittet MJ
COVID-19 diagnostics in context
Sci Transl Med. 2020;12(546):eabc1931 - PMID: 32493791 - DOI: 10.1126/scitranslmed.abc1931
Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R
Ultra-fast cycling for multiplexed cellular fluorescence imaging.
Angew Chem Int Ed Engl. 2020;59(17):6839-6846 - PMID: 32004403 - DOI: 10.1002/anie.201915153
Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT*, Mikula H*
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes.
J Am Chem Soc. 2020;142(45):19132-19141 - PMID: 33119297 - PMCID: PMC7662912 - DOI: 10.1021/jacs.0c07922
Chin LK*, Son T*, Hong JS, Liu AQ, Skog J, Castro CM, Weissleder R, Lee H*, Im H*
Plasmonic Sensors for Extracellular Vesicle Analysis: From Scientific Development to Translational Research.
ACS Nano. 2020;14(11):14528-14548 - PMID: 33119256 - PMCID: PMC8423498 - DOI: 10.1021/acsnano.0c07581
Li R, Ng TSC, Garlin MA, Weissleder R*, Miller MA*
Understanding the In Vivo Fate of Advanced Materials by Imaging
Adv Funct Mater. 2020;30(37):ePub - PMID: 38545084 - PMCID: PMC10972611 - DOI: 10.1002/adfm.201910369
Wang SJ, Li R, Ng TSC, Luthria G, Oudin MJ, Prytyskach M, Kohler RH, Weissleder R, Lauffenburger DA, Miller MA
Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy.
Sci Adv. 2020;6(21):ePub - PMID: 32937338 - PMCID: PMC7244320 - DOI: 10.1126/sciadv.aaz8521
Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R
Ultra-fast cycling for multiplexed cellular fluorescence imaging.
Angew Chem Weinheim Bergstr Ger. 2020;132(17):6906-6913 - PMID: 34366494 - PMCID: PMC8340598 - DOI: 10.1002/ange.201915153
Koch PD, Rodell CB, Kohler RH, Pittet MJ, Weissleder R
Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy.
Cell Chem Biol. 2020;27(1):94-104.e5 - PMID: 31902676 - PMCID: PMC7422681 - DOI: 10.1016/j.chembiol.2019.12.007
Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, Atanasova MI, Chylek LA, Shi T, Yi L, Nicora CD, Claas A, Ng TSC, Kohler RH, Lauffenburger DA, Weissleder R, Miller MA, Qian WJ, Wiley HS, Sorger PK
Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.
Cell Syst. 2020;11(5):478-494.e9 - PMID: 33113355 - PMCID: PMC8009031 - DOI: 10.1016/j.cels.2020.10.002
Calcagno DM, Ng RP, Toomu A, Zhang C, Huang K, Aguirre AD, Weissleder R, Daniels LB, Fu Z, King KR
Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and depend on Tet2, Nrf2, and Irf3
Sci Immunol. 2020;5(51):ePub - PMID: 32978242 - PMCID: PMC7808338 - DOI: 10.1126/sciimmunol.aaz1974
Pfirschke C, Engblom C, Gungabeesoon J, Lin Y, Rickelt S, Zilionis R, Messemaker M, Siwicki M, Gerhard GM, Kohl A, Meylan E, Weissleder R, Klein AM, Pittet MJ
Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils.
Cell Rep. 2020;32(12):108164 - PMID: 32966785 - PMCID: PMC7508173 - DOI: 10.1016/j.celrep.2020.108164
Ng TSC, Gunda V, Li R, Prytyskach M, Iwamoto Y, Kohler RH, Parangi S, Weissleder R, Miller MA
Detecting Immune Response to Therapies Targeting PDL1 and BRAF by Using Ferumoxytol MRI and Macrin in Anaplastic Thyroid Cancer
Radiology. 2020;298(1):123-132 - PMID: 33107799 - PMCID: PMC7771993 - DOI: 10.1148/radiol.2020201791
Weissleder R
The Magical World of Circulating Vesicles.
Adv Biosyst. 2020;4(12):e2000475 - PMID: 33274610 - DOI: 10.1002/adbi.202000475
Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R
Single Extracellular Vesicle Protein Analysis Using Immuno-Droplet Digital Polymerase Chain Reaction Amplification.
Adv Biosyst. 2020;4(12):e1900307 - PMID: 33274611 - PMCID: PMC8491538 - DOI: 10.1002/adbi.201900307
Yang KS, Lin HY, Curley C, Welch MW, Wolpin BM, Lee H, Weissleder R, Im H*, Castro CM*
Bead-Based Extracellular Vesicle Analysis Using Flow Cytometry.
Adv Biosyst. 2020;4(12):e2000203 - PMID: 33103361 - PMCID: PMC7718389 - DOI: 10.1002/adbi.202000203
Min J, Son T, Hong JS, Cheah PS Wegemann A, Murlidharan K, Weissleder R, Lee H, Im H
Plasmon-Enhanced Biosensing for Multiplexed Profiling of Extracellular Vesicles
Adv Biosyst. 2020;2020:2000003 - PMID: 32815321 - PMCID: PMC7718316 - DOI: 10.1002/adbi.202000003 - Cover
Ferguson S, Weissleder R
Modeling EV Kinetics for Use in Early Cancer Detection
Adv Biosyst. 2020;4(12):e1900305 - PMID: 32394646 - PMCID: PMC7658022 - DOI: 10.1002/adbi.201900305
Van Deun J, Jo A, Li H, Lin HY, Weissleder R, Im H, Lee H
Integrated Dual-Mode Chromatography to Enrich Extracellular Vesicles from Plasma.
Adv Biosyst. 2020;4(12):e1900310 - PMID: 32351054 - PMCID: PMC7606548 - DOI: 10.1002/adbi.201900310
Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R
Single Extracellular Vesicle Protein Analysis Using Immuno- Droplet Digital Polymerase Chain Reaction Amplification
Adv Biosyst. 2020;:ePub - DOI: 10.1002/adbi.201900307
Nahrendorf M, Hoyer FF, Meerwaldt AE, van Leent MMT, Senders ML, Calcagno C, Robson PM, Soultanidis G, Pérez-Medina C, Teunissen AJP, Toner YC, Ishikawa K, Fish K, Sakurai K, van Leeuwen EM, Klein ED, Sofias AM, Reiner T, Rohde D, Aguirre AD, Wojtkiewicz G, Schmidt S, Iwamoto Y, Izquierdo-Garcia D, Caravan P, Swirski FK, Weissleder R, Mulder WJM
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs.
Circ Cardiovasc Imaging. 2020;13(10):e010586 - PMID: 33076700 - PMCID: PMC7583675 - DOI: 10.1161/CIRCIMAGING.120.010586
Pai SI, Faquin WC, Sadow PM, Pittet MJ, Weissleder R
New Technology on the Horizon: Fast Analytical Screening Technique FNA (FAST-FNA) Enables Rapid, Multiplex Biomarker Analysis in Head and Neck Cancers
Cancer Cytopathol. 2020;128(11):782-791 - PMID: 32841527 - PMCID: PMC8276888 - DOI: 10.1002/cncy.22305
Marquard AN, Carlson JCT, Weissleder R
Expanding the scope of antibody rebridging with new pyridazinedione-TCO constructs.
Bioconjug Chem. 2020;31(6):1616-1623 - PMID: 32286045 - PMCID: PMC7788567 - DOI: 10.1021/acs.bioconjchem.0c00155
Kilic T, Weissleder R, Lee H
Molecular and immunological diagnostic tests of COVID-19 – current status and challenges
iScience. 2020;23(8):101406 - PMID: 32771976 - PMCID: PMC7381402 - DOI: 10.1016/j.isci.2020.101406
Vinegoni C, Fumene Feruglio P, Courties G, Schmidt S, Hulsmans M, Lee S, Wang R, Sosnovik D, Nahrendorf M, Weissleder R
Fluorescence microscopy tensor imaging representations for large-scale dataset analysis.
Sci Rep. 2020;10(1):5632 - PMID: 32221334 - PMCID: PMC7101442 - DOI: 10.1038/s41598-020-62233-2
Figueiredo JL, Santa-Cruz F, Lima-Filho JL, Hilgendorf I, Aikawa M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK, Robbins CS
A durable murine model of spleen transplantation with arterial and venous anastomoses.
Sci Rep. 2020;10(1):3979 - PMID: 32132617 - PMCID: PMC7055260 - DOI: 10.1038/s41598-020-60983-7
Rodell CB, Baldwin P, Fernandez B, Weissleder R, Sridhar S, Dubach JM
Quantification of Cellular Drug Biodistribution Addresses Challenges in Evaluating in vitro and in vivo Encapsulated Drug Delivery.
Adv Ther (Weinh). 2020;4(3):ePub - PMID: 33997266 - PMCID: PMC8114878 - DOI: 10.1002/adtp.202000125
Fumene Feruglio P, Vinegoni C, Weissleder R
Extended dynamic range imaging for noise mitigation in fluorescence anisotropy imaging.
J Biomed Opt. 2020;25(8):ePub - PMID: 32820624 - PMCID: PMC7439791 - DOI: 10.1117/1.JBO.25.8.086003
Bachar Issa TH, Vinegoni C, Shaw A, Fumene Feruglio P, Weissleder R, Uminsky D
Video-Rate Acquisition Fluorescence Microscopy via Generative Adversarial Networks
EasyChair. 2020;:ePub
Koch PD, Pittet MJ, Weissleder R
The chemical biology of IL-12 production via the non-canonical NFkB pathway
RSC Chemical Biology. 2020;1:166-176 - PMID: 34458756 - PMCID: PMC8341911 - DOI: 10.1039/d0cb00022a
Raisbeck JC, Allen M, Weissleder R, Im H, Lee H
Evolution Strategies Converges to Finite Differences
arXiv. 2020;:ePub
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