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De Souza DC, Hebert N, Esrick EB, Ciuculescu MF, Archer NM, Armant M, Audureau, Brendel C, Di Caprio G, Galactéros F, Liu D, McCabe A, Morris E, Schonbrun E, Williams D, Wood DK, Williams DA, Bartolucci P, Higgins JM
Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling.
Nat Commun. 2023;14(1):5850 - PMID: 37730674 - PMCID: PMC10511721 - DOI: 10.1038/s41467-023-40923-5
Qiang Y, Sissoko A, Liu ZL, Dong T, Zheng F, Kong F, Higgins JM, Karniadakis GE, Buffet PA, Suresh S, Dao M
Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease.
Proc Natl Acad Sci U S A. 2023;120(6):e2217607120 - PMID: 36730189 - PMCID: PMC9963977 - DOI: 10.1073/pnas.2217607120
Foy B, Stefely J, Bendapudi PK, Hasserjian RP, Al-Samkari H, Louissaint A, Fitzpatrick M, Hutchison B, Mow C, Collins J, Patel H, Patel C, Patel N, Ho S, Kaufman RM, Dzik W', Higgins JM, Makar RS
Computer vision quantitation of erythrocyte shape abnormalities provides diagnostic, prognostic, and mechanistic insight.
Blood Adv. 2023;7(16):4621-4630 - PMID: 37146262 - PMCID: PMC10448422 - DOI: 10.1182/bloodadvances.2022008967
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