Naxerova, Kamila, PhD
Kamila Naxerova received her B.Sc. in Molecular Biotechnology with a specialization in bioinformatics from Heidelberg University in Germany, and her Ph.D. in Human Biology and Translational Medicine from Harvard University in Cambridge, MA. She completed her postdoctoral training with Dr. Stephen J. Elledge at Harvard Medical School. She is interested in using computational and high-throughput experimental approaches to elucidate the evolutionary history of human cancer. Dr. Naxerova is a recipient of the Breakthrough Award from the U.S. Department of Defense.
Consecutive seeding and transfer of genetic diversity in metastasis.
Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.
Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns.
Cardiac macrophages promote diastolic dysfunction.
Electrical Conduction in the Heart
Origins of lymphatic and distant metastases in human colorectal cancer.
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation.
Stress granule-associated protein G3BP2 regulates breast tumor initiation.
Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma.
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Taking the brakes off telomerase.
Using tumour phylogenetics to identify the roots of metastasis in humans.
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment.
Hypermutable DNA chronicles the evolution of human colon cancer.
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors.
TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.
PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.
DNA hypermethylation in lung cancer is targeted at differentiation-associated genes.
Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers.
Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns.