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Dubach, John, PhD

John_dubach
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Email: dubach.john@mgh.harvard.edu
Lab: Weissleder, Ralph

Publications

Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.
Nat Commun. 2017;8:14293 - PMID: 28176769 - PMCID: PMC5309815
Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R
Quantitating drug-target engagement in single cells in vitro and in vivo.
Nat Chem Biol. 2016;13(2):168-173 - PMID: 27918558
Vinegoni C, Dubach JM, Feruglio PF, Weissleder R
Two-Photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement
IEEE J Sel Top Quantum Electron. 2016;22 (3):6801607 - PMID: 27440991 - PMCID: PMC4946648
Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R
Advances in measuring single-cell pharmacokinetics and pharmacology in vivo.
Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932
Kim E, Yang K, Kohler R, Dubach JM, Mikula H, Weissleder R
Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression.
Bioconjug Chem. 2015;26(8):1513-1518 - PMID: 26017814 - PMCID: PMC4772718
Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R
In vivo imaging of specific drug-target binding at subcellular resolution.
Nat Commun. 2014;5:3946 - PMID: 24867710 - PMCID: PMC4362617
Dubach JM, Vinegoni C, Weissleder R
Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging.
Opt Lett. 2014;39(15):4482-4485 - PMID: 25078208 - PMCID: PMC4341989
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