Im, Hyungsoon, PhD
Associate ProfessorDr. Im received his PhD in Electrical Engineering from the University of Minnesota, Twin-Cities. He trained as a NIH postdoctoral fellow in Biomedical Engineering and Systems Biology under Dr. Weissleder and Dr. Lee at MGH. He has expertise in nanofabrication, spectroscopy, microfluidics and imaging. His lab focuses on developing the next-generation diagnostic technology.
Selected Publications (from total 101)
Hong J, Conteduca D, Hong JS, Im H
Molecular Analysis of Single Tumor-Derived Extracellular Vesicles with Improved Robustness and Accuracy. Anal Chem. 2026;98(22):16032-16041 - PMID: 42166667 - PMCID: PMC13196386 - DOI: 10.1021/acs.analchem.5c07382Lee MY, Mangal U, Yoon HW, Im H, Choi SH, Kwon JS, Shin SJ
Microfluidic pulp platform with vascular integration to evaluate biofunctional material. Biomaterials . 2026;334:124221 - PMID: 42066433 - DOI: 10.1016/j.biomaterials.2026.124221Lee JB, Conteduca D, Jeong MH, Im H
Spatially Controlled Capture and Site-Resolved Analysis of Single Extracellular Vesicles. Small. 2026;22(31):e14514 - PMID: 41999595 - PMCID: PMC13130134 - DOI: 10.1002/smll.202514514Azizi M, Hong JS, Spitzberg J, Weissleder R, Castro CM, Im H
Hydrogel-based multiplexed high-risk human papillomavirus DNA/RNA detection for cervical cancer screening. Biosens Bioelectron X. 2025;26:ePub - PMID: 42273395 - PMCID: PMC13249390 - DOI: 10.1016/j.biosx.2025.100664Choi M, Jeong MH, Son T, Kwak TJ, Jo JH, Nahm JH, Weissleder R, Jang SI, Im H
Integrated Multi-Channel Automatic Cellular Profiling (iMAP) System for Cholangiocarcinoma Diagnosis. Small. 2025;22(2):e07120 - PMID: 41392743 - PMCID: PMC12747514 - DOI: 10.1002/smll.202507120Min J, Son T, Hong JS, Cheah PS Wegemann A, Murlidharan K, Weissleder R, Lee H, Im H
Plasmon-Enhanced Biosensing for Multiplexed Profiling of Extracellular Vesicles. Adv Biosyst. 2020;2020:2000003 - PMID: 32815321 - PMCID: PMC7718316 - DOI: 10.1002/adbi.202000003 - CoverYang KS*, Im H*, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R
Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy. Sci Transl Med. 2017;9(391):eaal3226 - PMID: 28539469 - PMCID: PMC5846089 - DOI: 10.1126/scitranslmed.aal3226Pathania D*, Im H*, Kilcoyne A, Sohani AR, Fexon L, Pivovarov M, Abramson JS, Randall TC, Chabner BA, Weissleder R, Lee H, Castro CM
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications. Theranostics. 2016;6(10):1603-10 - PMID: 27446494 - PMCID: PMC4955059 - DOI: 10.7150/thno.15534Im H, Park YI, Pathania D, Castro CM, Weissleder R, Lee H
Digital diffraction detection of protein markers for avian influenza. Lab Chip. 2016;16(8):1340-5 - PMID: 26980325 - PMCID: PMC4829473 - DOI: 10.1039/c5lc01558hIm H, Shao H, Weissleder R, Castro CM, Lee H
Nano-plasmonic exosome diagnostics. Expert Rev Mol Diagn. 2015;15(6):725-33 - PMID: 25936957 - PMCID: PMC4675626 - DOI: 10.1586/14737159.2015.1041378Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H*
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone. Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451 - DOI: 10.1073/pnas.1501815112Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H*
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor. Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947 - DOI: 10.1038/nbt.2886
