Publications

• Marshansky V, Hosokawa H, Merkulova M, Bakulina A, Dip PV, Thaker YR, Bjargava A, Tonra JR, Ausiello DA, Grüber G

  Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design. Curr Top Membr. 2019;83:77-106 - PMID: 31196611 - DOI: 10.1016/bs.ctm.2019.01.008

• Ausiello D, Shaw S

  Quantitative human phenotyping: the next frontier in medicine. Trans Am Clin Climatol Assoc. 2014;125:219-28 - PMID: 25125736 - PMCID: PMC4112685

• Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Gruber G, Marshansky V

  The N-terminus of a-Subunit Isoforms is Involved in Signaling between V-ATPase and Cytohesin-2. J Biol Chem. 2013;288(8):5896-913 - PMID: 23288846 - PMCID: PMC3581410 - DOI: 10.1074/jbc.M112.409169

• Bouley R, Nunes P, Andriopoulos B, McLaughlin MM, Webber MJ, Lin HY, Babitt JL, Gardella TJ, Ausiello DA, Brown D

  Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin. Am J Physiol Renal Physiol. 2012;304(5):F553-64 - PMID: 23235478 - PMCID: PMC3602717 - DOI: 10.1152/ajprenal.00438.2011

• Chen S, Webber MJ, Vilardaga JP, Khatri A, Brown D, Ausiello DA, Lin HY, Bouley R

  Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand. Endocrinology. 2011;152(10):3893-904 - PMID: 21828182 - PMCID: PMC3176653 - DOI: 10.1210/en.2011-1049

• Merkulova M, Hurtado-Lorenzo A, Hosokawa H, Zhuang Z, Brown D, Ausiello DA, Marshansky V

  Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution. Am J Physiol Cell Physiol. 2011;300(6):C1442-55 - PMID: 21307348 - PMCID: PMC3118619 - DOI: 10.1152/ajpcell.00076.2010

• Brown D, Breton S, Ausiello DA, Marshansky V

  Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology. Traffic. 2009;10(3):275-84 - PMID: 19170982 - PMCID: PMC2896909 - DOI: 10.1111/j.1600-0854.2008.00867.x

• Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA

  Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney Int. 2008;74(12):1557-67 - PMID: 18813286 - PMCID: PMC3730289 - DOI: 10.1038/ki.2008.412

• Yi X, Bouley R, Lin HY, Bechoua S, Sun TX, Del Re E, Shioda T, Raychowdhury MK, Lu HA, Abou-Samra AB, Brown D, Ausiello DA

  Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R. Am J Physiol Renal Physiol. 2007;292(5):F1303-13 - PMID: 17287200 - DOI: 10.1152/ajprenal.00441.2005

• Bouley R, Hawthorn G, Russo L, Lin H, Ausiello D, Brown D

  Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment. Biol Cell. 2006;98(4):215-32 - PMID: 16563128 - DOI: 10.1042/BC20040054

• Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V

  V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006;8(2):124-36 - PMID: 16415858 - DOI: 10.1038/ncb1348

• Bouley R, Lin HY, Raychowdhury MK, Marshansky V, Brown D, Ausiello DA

  Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway. Am J Physiol Cell Physiol. 2005;288(6):C1390-401 - PMID: 15677378 - DOI: 10.1152/ajpcell.00353.2004

• Bouley R, Hawthorn G, Russo L, Lin HY, Ausiello D, Brown D

  Aquaporin 2 (AQP2) and vasopressin receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in "endocytosis-resistant" membrane domains after vasopressin treatment. Abdom Imaging. 2005;:ePub - PMID: 16104839

• El-Annan J, Brown D, Breton S, Bourgoin S, Ausiello DA, Marshansky V

  Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ. Am J Physiol Cell Physiol. 2003;286(4):C768-78 - PMID: 14684384 - DOI: 10.1152/ajpcell.00250.2003

• Marshansky V, Ausiello DA, Brown D

  Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr Opin Nephrol Hypertens. 2002;11(5):527-37 - PMID: 12187318 - DOI: 10.1097/00041552-200209000-00009

• Tekirian TL, Merriam DE, Marshansky V, Miller J, Crowley AC, Chan H, Ausiello D, Brown D, Buxbaum JD, Xia W, Wasco W

  Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments. Brain Res Mol Brain Res. 2001;96(1-2):14-20 - PMID: 11731004 - DOI: 10.1016/s0169-328x(01)00250-9

• Maranda B, Brown D, Bourgoin S, Casanova JE, Vinay P, Ausiello DA, Marshansky V

  Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes. J Biol Chem. 2001;276(21):18540-50 - PMID: 11278939 - DOI: 10.1074/jbc.M011577200

• Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM

  RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport. Mol Biol Cell. 2000;11(9):3155-68 - PMID: 10982407 - PMCID: PMC14982 - DOI: 10.1091/mbc.11.9.3155

• Bouley R, Breton S, Sun T, McLaughlin M, Nsumu NN, Lin HY, Ausiello DA, Brown D

  Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells. J Clin Invest. 2000;106(9):1115-26 - PMID: 11067864 - PMCID: PMC301414 - DOI: 10.1172/JCI9594