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Baruch EN, Gleber-Netto FO, Nagarajan P, Rao X, Akhter S, Eichwald T, Xie T, Balood M, Adewale A, Naara S, Sathishkumar HN, Islam S, McCarthy W, Mattson BJ, Ferrarotto R, Wong MK, Davies MA, Jindal S, Basu S, Roversi K, Nikpoor AR, Ahmadi M, Ahmadi A, Harwood C, Leigh I, Gong D, Tallón de Lara P, Tao DL, Davidson TM, Ajami NJ, Futreal A, Rai K, Kochat V, Castillo M, Gunaratne P, Goepfert RP, Hernandez SD, Khushalani NI, Wang J, Watowich SS, Calin GA, Migden MR, Yuan M, Liu N, Ye Y, Hwang WL, Vermeer PD, D'Silva NJ, Bunimovich YL, Yaniv D, Burks JK, Gomez J, Dougherty PM, Tsai KY, Allison JP, Sharma P, Wargo JA, Myers JN, Talbot S, Gross ND, Amit M

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy.
Nature. 2025;646(8084):462-473 - PMID: 40836096 - PMCID: PMC12406299 - DOI: 10.1038/s41586-025-09370-8

Jones G, Anderson JL, Nguyen PTT, Gleber-Netto FO, Hwang WL, Puduvalli VK, Monje M, Amit M

Novel approaches to clinical trial design in cancer neuroscience.
Neuron. 2025;113(17):2791-2813 - PMID: 40907474 - PMCID: PMC12435926 - DOI: 10.1016/j.neuron.2025.08.015

Gong D, Liu R, Cui Y, Rhodes M, Bae JW, Beechem JM, Hwang WL

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer.
Sci Adv. 2025;11(42):eadx0632 - PMID: 41105767 - PMCID: PMC12533583 - DOI: 10.1126/sciadv.adx0632

Danaher P, McGuire D, Wu L, Patrick M, Kroeppler D, Zhai H, Olgun DG, Gong D, Cao J, Hwang WL, Schmid J, Beechem JM

InSituCor: exploring spatially correlated genes conditional on the cell type landscape.
Genome Biol. 2025;26(1):105 - PMID: 40275395 - PMCID: PMC12020328 - DOI: 10.1186/s13059-025-03554-1

Guo JA, Gong D, Evans K, Takahashi K, Jambhale AD, Shiau C, Yu P, Wang S, Wu WW, Chugh S, Kapner KS, Dilly J, Zhao D, Chen P, Smith EL, Mancias JD, Vazquez F, Singh H, Hwang WL, Aguirre AJ

Integrative genomic identification of therapeutic targets for pancreatic cancer.
Cell Rep. 2025;44(9):116191 - PMID: 40848256 - DOI: 10.1016/j.celrep.2025.116191

Wang P, Lester N, Perrault E, Su J, Gong D, Shiau C, Cao J, Nguyen P, Bae JW, Olgun D, Hoffman H, Lam A, Huang-Gao J, Rahaman S, Guo J, Barth J, Caldwell N, Divakar P, Reeves J, Bahrami A, He S, Patrick M, Miller E, Ganci M, Cervantes-Jaramillo G, Hong T, Wo J, Roberts H, Weissleder R, Choi H, Fernandez-Del-Castillo C, Cormier K, Ting DT, Jacks T, Zheng L, Hemberg M, Mino-Kenudson M, Hwang WL

The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer.
bioRxiv. 2025;:ePub - PMID: 40909696 - PMCID: PMC12407889 - DOI: 10.1101/2025.08.26.672505

Arbesfeld-Qiu JM, Cho JW, Nguyen PTT, Lester NA, Su J, Guo JA, Hoffman H, Shiau C, Caldwell N, Muratani S, Galvan M, Proctor JE, Ely Z, Wang S, Ganci M, Dries R, Hong T, Wo J, Boland G, Fernandez-Del Castillo C, Ferrone C, Heaphy CM, Zhang ML, Mino-Kenudson M, Hemberg M, Hwang WL

Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumors.
bioRxiv. 2025;:ePub - PMID: 40791359 - PMCID: PMC12338628 - DOI: 10.1101/2025.07.15.664730

Gong D, Liu R, Cui Y, Rhodes M, Bae JW, Beechem JM, Hwang WL

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer.
bioRxiv. 2025;:ePub - PMID: 40161804 - PMCID: PMC11952565 - DOI: 10.1101/2025.03.12.642933
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