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Kaiser Y, Garris CS, Marinari E, Kim HS, Oh J, Pedard M, Halabi EA, Choi M, Parvanian S, Kohler R, Migliorini D, Weissleder R

Targeting immunosuppressive myeloid cells via implant-mediated slow release of small molecules to prevent glioblastoma recurrence
Nat Biomed Eng. 2025;:ePub - PMID: 41125869 - DOI: 10.1038/s41551-025-01533-2

Zitti B, Duval F, Wirapati P, Hicham M, Xie Y, Oh J, Hoelzl J, Meiser P, Varrone M, Peterson HM, Cianciaruso C, Bill R, Bayerl F, Bolli E, Goubet AG, Kiss M, McDowell S, Cheng P, Celestini D, Terzic J, Zwahlen T, Alouche N, Zouggari N, Tarussio D, Tissot S, Nunes-Hasler P, Mino-Kenudson M, Lanuti M, Faquin WC, Sadow PM, Tille JC, Intidhar Labidi-Galy S, Garris CS, Hugues S, Petrova TV, Ludewig B, Quezada S, Luther S, Mempel TR, Ciriello G, Pai SI, Michielin O, Böttcher JP, Weissleder R, Pittet MJ

Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity.
Immunity. 2025;:ePub - PMID: 41421339 - DOI: 10.1016/j.immuni.2025.11.020

Kim HS, Simpson GG, Carrothers J, Nguyen YTM, Kohler R, Hong S, Cha S, Kim DH, Garris CS, Weissleder R

A Myeloid Cell-Targeted Immunostimulant Cocktail (MyTai) Enhances Cancer Immunotherapy.
ACS Nano. 2025;19(41):36451-36464 - PMID: 41061756 - DOI: 10.1021/acsnano.5c10081

Parvanian S, Ge X, Garris CS

Recent developments in myeloid immune modulation in cancer therapy.
Trends Cancer. 2025;11(4):365-375 - PMID: 39794212 - DOI: 10.1016/j.trecan.2024.12.003

Qin T, Mattox AK, Campbell JS, Park JC, Shin KY, Li S, Sadow PM, Faquin WC, Micevic G, Daniels AJ, Haddad R, Garris CS, Pittet MJ, Mempel TR, ONeill A, Sartor MA, Pai SI

Epigenetic therapy sensitizes anti-PD-1 refractory head and neck cancers to immunotherapy rechallenge.
J Clin Invest. 2025;135(6):ePub - PMID: 40091844 - PMCID: PMC11910227 - DOI: 10.1172/JCI181671

Garris C, Dunn GP, Weissleder R

Targeting myeloid cell polarization to prevent GBM recurrence.
Mol Ther. 2025;:ePub - PMID: 41421347 - DOI: 10.1016/j.ymthe.2025.12.019

Oh J*, Hoelzl J*, Carlson JCT, Bill R, Peterson HM, Faquin WC, Pittet MJ, Pai SI, Weissleder R

Spatial analysis identifies DC niches as predictors of pembrolizumab therapy in head and neck squamous cell cancer
Cell Rep Med. 2025;6(5):102100 - PMID: 40311615 - PMCID: PMC12147904 - DOI: 10.1016/j.xcrm.2025.102100
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