Sort by:
Reset

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
Nat Med. 2019;25(8):1264-1269 - PMID: 31263286 - PMCID: PMC6919319 - DOI: 10.1038/s41591-019-0493-4

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA

Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
Nat Med. 2019;25(10):1627 - PMID: 31501535 - DOI: 10.1038/s41591-019-0573-5

Hogan C, Little BP, Carlson JCT, Freudenreich O, Ivkovic A, Baron JM

Case 5-2019: A 48-Year-Old Woman with Delusional Thinking and Paresthesia of the Right Hand.
N Engl J Med. 2019;380(7):665-674 - PMID: 30763197 - DOI: 10.1056/NEJMcpc1807495

Carlson JCT, Hogan C, Ivkovic A

Case 5-2019: A Woman with Delusional Thinking and Paresthesia of the Right Hand. Reply.
N Engl J Med. 2019;380(21):2082 - PMID: 31116941 - DOI: 10.1056/NEJMc1903635

He S*, Kahles F*, Rattik S*, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease
Nature. 2019;566(7742):115-119 - PMID: 30700910 - PMCID: PMC6367023 - DOI: 10.1038/s41586-018-0849-9

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK

Sleep modulates haematopoiesis and protects against atherosclerosis
Nature. 2019;566(7744):383-387 - PMID: 30760925 - PMCID: PMC6442744 - DOI: 10.1038/s41586-019-0948-2

Hovestadt V, Smith KS, Bihannic L, Filbin MG, Shaw ML, Baumgartner A, DeWitt JC, Groves A, Mayr L, Weisman HR, Richman AR, Shore ME, Goumnerova L, Rosencrance C, Carter RA, Phoenix TN, Hadley JL, Tong Y, Houston J, Ashmun RA, DeCuypere M, Sharma T, Flasch D, Silkov A, Ligon KL, Pomeroy SL, Rivera MN, Rozenblatt-Rosen O, Rusert JM, Wechsler-Reya RJ, Li XN, Peyrl A, Gojo J, Kirchhofer D, Lötsch D, Czech T, Dorfer C, Haberler C, Geyeregger R, Halfmann A, Gawad C, Easton J, Pfister SM, Regev A, Gajjar A, Orr BA, Slavc I, Robinson GW, Bernstein BE, Suvà ML, Northcott PA

Resolving medulloblastoma cellular architecture by single-cell genomics.
Nature. 2019;572(7767):74-79 - PMID: 31341285 - PMCID: PMC6754173 - DOI: 10.1038/s41586-019-1434-6

Flavahan WA, Drier Y, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD, Bernstein BE

Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST.
Nature. 2019;:ePub - PMID: 31618758 - DOI: 10.1038/s41586-019-1668-3

Vagnozzi RJ, Maillet M, Sargent MA, Khalil H, Johansen AK, Schwanekamp JA, York AJ, Huang V, Nahrendorf M, Sadayappan S, Molkentin JD

An acute immune response underlies the benefit of cardiac stem-cell therapy.
Nature. 2019;577(7790):405-409 - PMID: 31775156 - PMCID: PMC6962570 - DOI: 10.1038/s41586-019-1802-2

van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.
Cell. 2019;176(6):1265-1281.e24 - PMID: 30827681 - PMCID: PMC6515904 - DOI: 10.1016/j.cell.2019.01.031

Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà ML

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.
Cell. 2019;178(4):835-849.e21 - PMID: 31327527 - PMCID: PMC6703186 - DOI: 10.1016/j.cell.2019.06.024

Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.
Cancer Cell. 2019;36(5):528-544.e10 - PMID: 31631026 - DOI: 10.1016/j.ccell.2019.09.005

Zilionis R*, Engblom C*, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ**, Klein AM**

Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species.
Immunity. 2019;50(5):1317-1334.e10 - PMID: 30979687 - PMCID: PMC6620049 - DOI: 10.1016/j.immuni.2019.03.009

Hoyer FF*, Naxerova K*, Schloss MJ, Hulsmans M, Nair AV, Dutta P, Calcagno DM, Herisson F, Anzai A, Sun Y, Wojtkiewicz G, Rohde D, Frodermann V, Vandoorne K, Courties G, Iwamoto Y, Garris CS, Williams DL, Breton S, Brown D, Whalen M, Libby P, Pittet MJ, King KR, Weissleder R, Swirski FK, Nahrendorf M

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge.
Immunity. 2019;51(5):899-914.e7 - PMID: 31732166 - PMCID: PMC6892583 - DOI: 10.1016/j.immuni.2019.10.010

Swirski FK, Nahrendorf M

Reply to 'Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies'.
Nat Rev Immunol. 2019;19(1):65 - PMID: 30552386 - DOI: 10.1038/s41577-018-0099-y

Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Santos Masson G, Tesmenitsky Y, Folco E, Gram H, Nahrendorf M, Swirski FK, Sukhova GK, Libby P

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.
Eur Heart J. 2019;40(30):2482-2491 - PMID: 30698710 - PMCID: PMC6685323 - DOI: 10.1093/eurheartj/ehz008

Rohde D, Nahrendorf M

Clonal and diverse: revisiting cardiac endothelial cells after myocardial infarction.
Eur Heart J. 2019;40(30):2521-2522 - PMID: 31162523 - PMCID: PMC6685322 - DOI: 10.1093/eurheartj/ehz375

Jain IH, Zazzeron L, Goldberger O, Marutani E, Wojtkiewicz GR, Ast T, Wang H, Schleifer G, Stepanova A, Brepoels K, Schoonjans L, Carmeliet P, Galkin A, Ichinose F, Zapol WM, Mootha VK

Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation.
Cell Metab. 2019;30(4):824-832.e3 - PMID: 31402314 - PMCID: PMC6903907 - DOI: 10.1016/j.cmet.2019.07.006

Lee H, Castro CM

Thermophoretically enriched detection.
Nat Biomed Eng. 2019;3(3):163-164 - PMID: 30948812 - DOI: 10.1038/s41551-019-0364-9

Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells
Nature Med. 2019;25(11):1761-1771 - PMID: 31700184 - PMCID: PMC6858591 - DOI: 10.1038/s41591-019-0633-x

Hoyer FF, Nahrendorf M

Uremic Toxins Activate Macrophages.
Circulation. 2019;139(1):97-100 - PMID: 30592654 - PMCID: PMC6394415 - DOI: 10.1161/CIRCULATIONAHA.118.037308

RamÍrez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C

Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation.
Circulation. 2019;140(3):225-239 - PMID: 31154825 - PMCID: PMC6778687 - DOI: 10.1161/CIRCULATIONAHA.118.038571

Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K

Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction.
Circulation. 2019;140(6):487-499 - PMID: 31170826 - PMCID: PMC6684855 - DOI: 10.1161/CIRCULATIONAHA.118.038820

Cruz Hernández JC, Bracko O, Kersbergen CJ, Muse V, Haft-Javaherian M, Berg M, Park L, Vinarcsik LK, Ivasyk I, Rivera DA, Kang Y, Cortes-Canteli M, Peyrounette M, Doyeux V, Smith A, Zhou J, Otte G, Beverly JD, Davenport E, Davit Y, Lin CP, Strickland S, Iadecola C, Lorthois S, Nishimura N, Schaffer CB

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.
Nat Neurosci. 2019;22(3):413-420 - PMID: 30742116 - PMCID: PMC6508667 - DOI: 10.1038/s41593-018-0329-4

Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Crist C, Brack AS

Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress.
Cell Stem Cell. 2019;24(6):944-957.e5 - PMID: 31006621 - PMCID: PMC6597014 - DOI: 10.1016/j.stem.2019.03.020

Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT

Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.
Cell Stem Cell. 2019;25(4):570-583.e7 - PMID: 31279774 - PMCID: PMC6778015 - DOI: 10.1016/j.stem.2019.06.003

Liu JF, Herold C, Gray KP, Penson RT, Horowitz N, Konstantinopoulos PA, Castro CM, Hill SJ, Curtis J, Luo W, Matulonis UA, Cannistra SA, Dizon DS

Assessment of Combined Nivolumab and Bevacizumab in Relapsed Ovarian Cancer: A Phase 2 Clinical Trial.
JAMA Oncol. 2019;5(12):1731-1738 - PMID: 31600397 - PMCID: PMC6802049 - DOI: 10.1001/jamaoncol.2019.3343

Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K

Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Nat Cell Biol. 2019;21(11):1449-1461 - PMID: 31659274 - PMCID: PMC6858577 - DOI: 10.1038/s41556-019-0403-5

Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Nat Metab. 2019;1(5):519-531 - PMID: 31276102 - PMCID: PMC6609153 - DOI: 10.1038/s42255-019-0063-6

Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.
J Am Coll Cardiol. 2019;73(23):2990-3002 - PMID: 31196457 - DOI: 10.1016/j.jacc.2019.03.503

Tawakol A, Osborne MT, Wang Y, Hammed B, Tung B, Patrich T, Oberfeld B, Ishai A, Shin LM, Nahrendorf M, Warner ET, Wasfy J, Fayad ZA, Koenen K, Ridker PM, Pitman RK, Armstrong KA

Stress-Associated Neurobiological Pathway Linking Socioeconomic Disparities to Cardiovascular Disease.
J Am Coll Cardiol. 2019;73(25):3243-3255 - PMID: 31248544 - PMCID: PMC6767929 - DOI: 10.1016/j.jacc.2019.04.042

Libby P, Swirski FK, Nahrendorf M

The Myocardium: More Than Myocytes.
J Am Coll Cardiol. 2019;74(25):3136-3138 - PMID: 31856970 - DOI: 10.1016/j.jacc.2019.10.031

Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.
Sci Transl Med. 2019;11(506):ePub - PMID: 31434756 - PMCID: PMC7328283 - DOI: 10.1126/scitranslmed.aaw7736

Naxerova K

A new function for polycomb in immune evasion
Sci Transl Med. 2019;11(514):eaaz3718 - DOI: 10.1126/scitranslmed.aaz3718

Harisinghani MG, O’Shea A, Weissleder R

Advances in clinical MRI technology
Sci Transl Med. 2019;11 (523):eaba2591 - PMID: 31852796 - DOI: 10.1126/scitranslmed.aba2591

Naxerova K

Tumor mutations are not alone in the plasma
Sci Transl Med. 2019;11(522):eaaz9767 - DOI: 10.1126/scitranslmed.aaz9767

Naxerova K

Interrogating CD8+ T cell reactivity on a genome-wide scale
Sci Transl Med. 2019;11(506):eaaz0302 - DOI: 10.1126/scitranslmed.aaz0302

Naxerova K

From micrographs to microsatellites in one bold step
Sci Transl Med. 2019;11(498):eaax9570 - DOI: 10.1126/scitranslmed.aax9570

Naxerova K

Somatic mutations are improving their bad rap
Sci Transl Med. 2019;11(490):eaax4871 - DOI: 10.1126/scitranslmed.aax4871

Choudhary A, Manna D, Maji B, Gangopadhyay SA, Cox KJ, Zhou Q, Law B, Mazitschek R

A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9.
Angew Chem Int Ed Engl. 2019;58(19):6285-6289 - PMID: 30834641 - PMCID: PMC7067309 - DOI: 10.1002/anie.201900788

Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA

Radiation-Induced Targeted Nanoparticle- Based Gene Delivery for Brain Tumor Therapy
ACS Nano. 2019;13(4):4028-4040 - PMID: 30916923 - PMCID: PMC7104714 - DOI: 10.1021/acsnano.8b08177

Huang CH, Park YI, Lin HY, Pathania D, Park KS, Avila-Wallace M, Castro CM, Weissleder R, Lee H

Compact and Filter-Free Luminescence Biosensor for Mobile In-Vitro Diagnoses.
ACS Nano. 2019;13(10):11698-11706 - PMID: 31461265 - PMCID: PMC7307311 - DOI: 10.1021/acsnano.9b05634

Courties G, Frodermann V, Honold L, Zheng Y, Herisson FE, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden D, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M

Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke.
Circ Res. 2019;124(9):1372-1385 - PMID: 30782088 - PMCID: PMC6483874 - DOI: 10.1161/CIRCRESAHA.118.314518

Hulsmans M, Nahrendorf M

Smad3 Cranks Up the Appetite of Infarct Macrophages.
Circ Res. 2019;125(1):71-73 - PMID: 31219739 - PMCID: PMC6588180 - DOI: 10.1161/CIRCRESAHA.119.315306

Park SG, Xiao X, Min J, Mun CW, Jung HS, Giannini V, Weissleder R, Maier SA, Im H, Kim DH

Self‐Assembly of Nanoparticle‐Spiked Pillar Arrays for Plasmonic Biosensing
Adv Funct Mater. 2019;29(43):1904257 - DOI: 10.1002/adfm.201904257

Yekula A, Minciacchi VR, Morello M, Shao H, Park Y, Zhang X, Muralidharan K, Freeman MR, Weissleder R, Lee H, Carter B, Breakefield XO, Di Vizio D, Balaj L

Large and small extracellular vesicles released by glioma cells in vitro and in vivo.
J Extracell Vesicles. 2019;9(1):1689784 - PMID: 31839905 - PMCID: PMC6896449 - DOI: 10.1080/20013078.2019.1689784

Liu P, Zhao L, Pol J, Levesque S, Petrazzuolo A, Pfirschke C, Engblom C, Rickelt S, Yamazaki T, Iribarren K, Senovilla L, Bezu L, Vacchelli E, Sica V, Melis A, Martin T, Xia L, Yang H, Li Q, Chen J, Durand S, Aprahamian F, Lefevre D, Broutin S, Paci A, Bongers A, Minard-Colin V, Tartour E, Zitvogel L, Apetoh L, Ma Y, Pittet MJ, Kepp O, Kroemer G

Crizotinib-induced immunogenic cell death in non-small cell lung cancer.
Nat Commun. 2019;10(1):1486 - PMID: 30940805 - PMCID: PMC6445096 - DOI: 10.1038/s41467-019-09415-3

Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, Furman RR, Gnirke A, Wu CJ, Melnick AM, Meissner A, Bernstein BE, Abdel-Wahab O, Landau DA

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nat Commun. 2019;10(1):1874 - PMID: 31015400 - PMCID: PMC6478836 - DOI: 10.1038/s41467-019-09645-5

Liu CL, Zhang X, Liu J, Wang Y, Sukhova GK, Wojtkiewicz GR, Liu T, Tang R, Achilefu S, Nahrendorf M, Libby P, Guo J, Zhang JY, Shi GP

Na+ - H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.
Nat Commun. 2019;10(1):3978 - PMID: 31484936 - PMCID: PMC6726618 - DOI: 10.1038/s41467-019-11983-3

Tarjan DR, Flavahan WA, Bernstein BE

Epigenome editing strategies for the functional annotation of CTCF insulators.
Nat Commun. 2019;10(1):4258 - PMID: 31534142 - PMCID: PMC6751197 - DOI: 10.1038/s41467-019-12166-w

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.
J Exp Med. 2019;216(2):369-383 - PMID: 30670465 - PMCID: PMC6363430 - DOI: 10.1084/jem.20180722

Pai SI, Marincola FM

Peripheral Circulating CD45RA-FOXP3hi T Regulatory (TReg) II Cells Provide a Window into the Activity of Intratumoral TReg Cells.
Trends Cancer. 2019;6(1):3-6 - PMID: 31952778 - PMCID: PMC7390988 - DOI: 10.1016/j.trecan.2019.11.003

Duivenvoorden R, Senders ML, van Leent MMT, Pérez-Medina C, Nahrendorf M, Fayad ZA, Mulder WJM

Nanoimmunotherapy to treat ischaemic heart disease.
Nat Rev Cardiol. 2019;16(1):21-32 - PMID: 30209355 - PMCID: PMC10621601 - DOI: 10.1038/s41569-018-0073-1

Kalman JM, Lavandero S, Mahfoud F, Nahrendorf M, Yacoub MH, Zhao D

Looking back and thinking forwards - 15 years of cardiology and cardiovascular research.
Nat Rev Cardiol. 2019;16(11):651-660 - PMID: 31570832 - DOI: 10.1038/s41569-019-0261-7

Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.
Proc Natl Acad Sci U S A. 2019;116(22):10674-10680 - PMID: 31040208 - PMCID: PMC6561160 - DOI: 10.1073/pnas.1819889116

Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ

A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor
Proc Natl Acad Sci U S A. 2019;116(23):11444-11453 - PMID: 31101720 - PMCID: PMC6561274 - DOI: 10.1073/pnas.1702372116

Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo.
Proc Natl Acad Sci U S A. 2019;116(24):11966-11971 - PMID: 31123149 - PMCID: PMC6575581 - DOI: 10.1073/pnas.1818434116

Babitt JL

Ironing out pulmonary arterial hypertension.
Proc Natl Acad Sci U S A. 2019;116(26):12604-12606 - PMID: 31171658 - PMCID: PMC6601273 - DOI: 10.1073/pnas.1908298116

Heyde A, Reiter JG, Naxerova K, Nowak MA

Consecutive seeding and transfer of genetic diversity in metastasis.
Proc Natl Acad Sci U S A. 2019;116(28):14129-14137 - PMID: 31239334 - PMCID: PMC6628640 - DOI: 10.1073/pnas.1819408116

Di Caprio G*, Schonbrun E*, Gonçalves BP, Valdez JM, Wood DK, Higgins JM

High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension.
Proc Natl Acad Sci U S A. 2019;116(50):25236-25242 - PMID: 31767751 - PMCID: PMC6911208 - DOI: 10.1073/pnas.1914056116

Ippen FM, Alvarez-Breckenridge CA, Kuter BM, Fink AL, Bihun IV, Lastrapes M, Penson T, Schmidt SP, Wojtkiewicz GR, Ning J, Subramanian M, Giobbie-Hurder A, Martinez-Lage M, Carter SL, Cahill DP, Wakimoto H, Brastianos PK

The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA-Mutant Breast Cancer Brain Metastases.
Clin Cancer Res. 2019;25(11):3374-3383 - PMID: 30796030 - PMCID: PMC6685218 - DOI: 10.1158/1078-0432.CCR-18-3049

Pai SI, Faivre S, Licitra L, Machiels JP, Vermorken JB, Bruzzi P, Gruenwald V, Giglio RE, Leemans CR, Seiwert TY, Soulieres D

Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040).
J Immunother Cancer. 2019;7(1):96 - PMID: 30944020 - PMCID: PMC6446400 - DOI: 10.1186/s40425-019-0578-0

Bae SH, Jo A, Park JH, Lim CW, Choi Y, Oh J, Park JM, Kong T, Weissleder R, Lee H, Moon J

Bioassay for monitoring the anti-aging effect of cord blood treatment.
Theranostics. 2019;9(1):1-10 - PMID: 30662549 - PMCID: PMC6332798 - DOI: 10.7150/thno.30422

Pathania D, Landeros C, Rohrer L, D’Agostino V, Hong S, Degani I, Avila-Wallace M, Pivovarov M, Randall T, Weissleder R, Lee H, Im H, Castro CM

Point-of-care cervical cancer screening using deep learning-based microholography
Theranostics. 2019;9(26):8438-8447 - PMID: 31879529 - PMCID: PMC6924258 - DOI: 10.7150/thno.37187

Ng TSC, Garlin MA, Weissleder R, Miller MA

Understanding the EPR effect through image-guided systems pharmacology
Theranostics. 2019;:ePub

Rodell CB, Ahmed MS, Garris CS, Pittet MJ, Weissleder R

Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy
Theranostics. 2019;9(26):8426-8436 - PMID: 31879528 - PMCID: PMC6924259 - DOI: 10.7150/thno.35434

Rodell CB, Koch PD, Weissleder R

Screening for new macrophage therapeutics.
Theranostics. 2019;9(25):7714-7729 - PMID: 31695796 - PMCID: PMC6831478 - DOI: 10.7150/thno.34421

Wang C, Pulli B, Jalali Motlagh N, Li A, Wojtkiewicz GR, Schmidt SP, Wu Y, Zeller MWG, Chen JW

A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales.
Theranostics. 2019;9(25):7525-7536 - PMID: 31695784 - PMCID: PMC6831463 - DOI: 10.7150/thno.36264

Cheung PW, Bouley R, Brown D

Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit.
Annu Rev Pharmacol Toxicol. 2019;60:175-194 - PMID: 31561739 - PMCID: PMC7334826 - DOI: 10.1146/annurev-pharmtox-010919-023654

Wang CY, Xiao X, Bayer A, Xu Y, Dev S, Canali S, Nair AV, Masia R, Babitt JL

Ablation of hepatocyte Smad1, Smad5 and Smad8 causes severe tissue iron loading and liver fibrosis in mice.
Hepatology. 2019;70(6):1986-2002 - PMID: 31127639 - PMCID: PMC6874904 - DOI: 10.1002/hep.30780

Hwang WL, Wolfson RL, Niemierko A, Marcus KJ, DuBois SG, Haas-Kogan D

Clinical Impact of Tumor Mutational Burden in Neuroblastoma.
J Natl Cancer Inst. 2019;111(7):695-699 - PMID: 30307503 - PMCID: PMC6624164 - DOI: 10.1093/jnci/djy157

Hoyer FF, Nahrendorf M

Interferon-ɣ regulates cardiac myeloid cells in myocardial infarction.
Cardiovasc Res. 2019;115(13):1815-1816 - PMID: 31161218 - PMCID: PMC6803813 - DOI: 10.1093/cvr/cvz143

Yassin M, Aqaqe N, Yassin AA, van Galen P, Kugler E, Bernstein BE, Koren-Michowitz M, Canaani J, Nagler A, Lechman ER, Dick JE, Wienholds E, Izraeli S, Milyavsky M

A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity.
Leukemia. 2019;33(8):2061-2077 - PMID: 30705411 - DOI: 10.1038/s41375-019-0386-z

Ho M, Chen T, Liu J, Dowling P, Hideshima T, Zhang L, Morelli E, Camci-Unal G, Wu X, Tai YT, Wen K, Samur M, Schlossman RL, Mazitschek R, Kavanagh EL, Lindsay S, Harada T, McCann A, Anderson KC, O'Gorman P, Bianchi G

Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling.
Leukemia. 2019;34(1):196-209 - PMID: 31142847 - PMCID: PMC6883144 - DOI: 10.1038/s41375-019-0493-x

Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R

Characterization of single microvesicles in plasma from glioblastoma patients.
Neuro Oncol. 2019;21(5):606-615 - PMID: 30561734 - PMCID: PMC6502493 - DOI: 10.1093/neuonc/noy187

Morini E, Gao D, Montgomery CM, Salani M, Mazzasette C, Krussig TA, Swain B, Dietrich P, Narasimhan J, Gabbeta V, Dakka A, Hedrick J, Zhao X, Weetall M, Naryshkin NA, Wojtkiewicz GG, Ko CP, Talkowski ME, Dragatsis I, Slaugenhaupt SA

ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia.
Am J Hum Genet. 2019;104(4):638-650 - PMID: 30905397 - PMCID: PMC6451698 - DOI: 10.1016/j.ajhg.2019.02.009

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Boerger EAS, Mc Causland FR, Eisenga MF, Singh K, Babitt JL, Kellum JA, Palevsky PM, Christov M, Waikar SS

Iron, Hepcidin, and Death in Human AKI.
J Am Soc Nephrol. 2019;30(3):493-504 - PMID: 30737269 - PMCID: PMC6405140 - DOI: 10.1681/ASN.2018100979

Chaudhury A, Miller GD, Eichner D, Higgins JM

Single-cell modeling of routine clinical blood tests reveals transient dynamics of human response to blood loss.
eLife. 2019;8:ePub - PMID: 31845889 - PMCID: PMC6917488 - DOI: 10.7554/eLife.48590

Ferder IC, Fung L, Ohguchi Y, Zhang X, Lassen KG, Capen D, Brown D, Xavier RJ, Wang N

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.
PLoS Genet. 2019;15(5):e1008084 - PMID: 31059511 - PMCID: PMC6502318 - DOI: 10.1371/journal.pgen.1008084

Chen J, Landegger LD, Sun Y, Ren J, Maimon N, Wu L, Ng MR, Chen JW, Zhang N, Zhao Y, Gao X, Fujita T, Roberge S, Huang P, Jain RK, Plotkin SR, Stankovic KM, Xu L

A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.
Nat Protoc. 2019;14(2):541-555 - PMID: 30617350 - PMCID: PMC6571021 - DOI: 10.1038/s41596-018-0105-7

Li A, Wu Y, Pulli B, Wojtkiewicz GR, Iwamoto Y, Wang C, Li JH, Ali M, Feng X, Yao Z, Chen JW

Myeloperoxidase Molecular MRI Reveals Synergistic Combination Therapy in Murine Experimental Autoimmune Neuroinflammation.
Radiology. 2019;293(1):158-165 - PMID: 31478802 - PMCID: PMC6776885 - DOI: 10.1148/radiol.2019182492

Niyazi M, Niemierko A, Paganetti H, Söhn M, Schapira E, Goldberg S, Adams J, Kim V, Oh KS, Hwang WL, Lu HM, Belka C, Busse PM, Loeffler JS, Shih HA

Volumetric and actuarial analysis of brain necrosis in proton therapy using a novel mixture cure model.
Radiother Oncol. 2019;142:154-161 - PMID: 31563411 - DOI: 10.1016/j.radonc.2019.09.008

Zaborowski MP, Lee K, Na YJ, Sammarco A, Zhang X, Iwanicki M, Cheah PS, Lin HY, Zinter M, Chou CY, Fulci G, Tannous BA, Lai CP, Birrer MJ, Weissleder R, Lee H, Breakefield XO

Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles.
Cell Rep. 2019;27(1):255-268.e6 - PMID: 30943406 - PMCID: PMC6528836 - DOI: 10.1016/j.celrep.2019.03.003

Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.
Cell Rep. 2019;27(8):2304-2312.e6 - PMID: 31116977 - DOI: 10.1016/j.celrep.2019.04.090

Gyuris A, Navarrete-Perea J, Jo A, Cristea S, Zhou S, Fraser K, Wei Z, Krichevsky AM, Weissleder R, Lee H, Gygi SP, Charest A

Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Cell Rep. 2019;27(13):3972-3987.e6 - PMID: 31242427 - PMCID: PMC6604862 - DOI: 10.1016/j.celrep.2019.05.089

Mindur JE, Swirski FK

Growth Factors as Immunotherapeutic Targets in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2019;39(7):1275-1287 - PMID: 31092009 - PMCID: PMC6613384 - DOI: 10.1161/ATVBAHA.119.311994

Lan YY, Heather JM, Eisenhaure T, Garris CS, Lieb D, Raychowdhury R, Hacohen N

Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation.
Aging Cell. 2019;18(2):e12901 - PMID: 30706626 - PMCID: PMC6413746 - DOI: 10.1111/acel.12901

Battistone MA, Spallanzani RG, Mendelsohn AC, Capen D, Nair AV, Brown D, Breton S

Novel role of proton-secreting epithelial cells in sperm maturation and mucosal immunity.
J Cell Sci. 2019;133(5):ePub - PMID: 31636115 - PMCID: PMC7003979 - DOI: 10.1242/jcs.233239

Cohen RM, Franco RS, Smith EP, Higgins JM

When the A1c and the blood glucose don't match: how much is determined by race, by genetics, by differences in mean red blood cell age?
J Clin Endocrinol Metab. 2019;104(3):707-710 - PMID: 30445523 - DOI: 10.1210/jc.2018-02409

Valdez JM, Datta YH, Higgins JM, Wood DK

A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood.
APL Bioeng. 2019;3(4):046102 - PMID: 31803859 - PMCID: PMC6881198 - DOI: 10.1063/1.5118212

Parikh AS, Puram SV, Faquin WC, Richmon JD, Emerick KS, Deschler DG, Varvares MA, Tirosh I, Bernstein BE, Lin DT

Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis.
Oral Oncol. 2019;99:104458 - PMID: 31704557 - PMCID: PMC7382966 - DOI: 10.1016/j.oraloncology.2019.104458

Sanford NN, Hwang WL, Pike LRG, Lam AC, Royce TJ, Mahal BA

Trimodality therapy for HPV-positive oropharyngeal cancer: A population-based study: Trimodality therapy for HPV+ OPC.
Oral Oncol. 2019;98:28-34 - PMID: 31536843 - PMCID: PMC7358785 - DOI: 10.1016/j.oraloncology.2019.09.009

Foy BH, Li A, McClung J, Ranganath R, Higgins JM

Data-driven physiologic thresholds for iron deficiency associated with hematologic decline.
Am J Hematol. 2019;95(3):302-309 - PMID: 31849101 - DOI: 10.1002/ajh.25706

Stokes KL, Cortez-Retamozo V, Acosta J, Lauderback B, Robles-Oteiza C, Cicchini M, Pittet MJ, Feldser DM

Natural killer cells limit the clearance of senescent lung adenocarcinoma cells.
Oncogenesis. 2019;8(4):24 - PMID: 30936429 - PMCID: PMC6443683 - DOI: 10.1038/s41389-019-0133-3

Rangarajan N, Gordy CL, Askew L, Bevill SM, Elston TC, Errede B, Hurst JH, Kelley JB, Sheetz JB, Suzuki SK, Valentin NH, Young E, Dohlman HG

Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway.
J Biol Chem. 2019;294(40):14717-14731 - PMID: 31399514 - PMCID: PMC6779436 - DOI: 10.1074/jbc.RA119.010063

Larkin M, Nathan DM, Bebu I, Krause-Steinrauf H, Herman WH, Higgins JM, Tiktin M, Cohen RM, Lund C, Bergenstal RM, Johnson M, Arends V, Research Group G

Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring.
Diabetes Technol Ther. 2019;21(12):682-690 - PMID: 31393176 - PMCID: PMC7207016 - DOI: 10.1089/dia.2019.0202

Battistone MA, Merkulova M, Park YJ, Peralta MA, Gombar F, Brown D, Breton S

Unraveling purinergic regulation in the epididymis: Activation of V-ATPase-dependent acidification by luminal ATP and adenosine.
J Physiol. 2019;597(7):1957-1973 - PMID: 30746715 - PMCID: PMC6441927 - DOI: 10.1113/JP277565

Koch PD, Ahmed MS, Kohler RH, Li R, Weissleder R

Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand.
ACS Chem Biol. 2019;15(1):151-157 - PMID: 31809013 - PMCID: PMC7808335 - DOI: 10.1021/acschembio.9b00724

Fagbami L, Deik AA, Herman JD, Singh K, Santos SA, Bopp S, Lukens AK, Clish CB, Wirth DF, Mazitschek R

The adaptive proline response in P. falciparum is independent of PfeIK1 and eIF2α signaling.
ACS Infect Dis. 2019;5(4):515-520 - PMID: 30773881 - PMCID: PMC6747701 - DOI: 10.1021/acsinfecdis.8b00363

Tan X, Patil R, Bartosik P, Runnels JM, Lin CP, Niedre M

In Vivo Flow Cytometry of Extremely Rare Circulating Cells.
Sci Rep. 2019;9(1):3366 - PMID: 30833671 - PMCID: PMC6399281 - DOI: 10.1038/s41598-019-40143-2

Zaborowski MP, Cheah PS, Zhang X, Bushko I, Lee K, Sammarco A, Zappulli V, Maas SLN, Allen RM, Rumde P, György B, Aufiero M, Schweiger MW, Lai CP, Weissleder R, Lee H, Vickers KC, Tannous BA, Breakefield XO

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles.
Sci Rep. 2019;9(1):17387 - PMID: 31758005 - PMCID: PMC6874653 - DOI: 10.1038/s41598-019-53554-y

Krasner CN, Castro C, Penson RT, Roche M, Matulonis UA, Morgan MA, Drescher C, Armstrong DK, Wolfe JK, Lee H, Supko JG, Seiden M, Birrer MJ, Dizon DS

Final report on serial phase II trials of all-intraperitoneal chemotherapy with or without bevacizumab for women with newly diagnosed, optimally cytoreduced carcinoma of Müllerian origin.
Gynecol Oncol. 2019;153(2):223-229 - PMID: 30765148 - DOI: 10.1016/j.ygyno.2019.02.004

Bassir SH, Garakani S, Wilk K, Aldawood ZA, Hou J, Yeh SA, Sfeir C, Lin CP, Intini G

Prx1 Expressing Cells Are Required for Periodontal Regeneration of the Mouse Incisor.
Front Physiol. 2019;10:591 - PMID: 31231227 - PMCID: PMC6558369 - DOI: 10.3389/fphys.2019.00591

Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre A, Nahrendorf M, Weissleder R

A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart.
Bioconjug Chem. 2019;30(3):733-740 - PMID: 30615425 - PMCID: PMC6483069 - DOI: 10.1021/acs.bioconjchem.8b00882

Babitt JL, Sitara D

Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease.
Curr Opin Nephrol Hypertens. 2019;28(4):304-310 - PMID: 31145704 - PMCID: PMC6693648 - DOI: 10.1097/MNH.0000000000000514

Nair AV, Yanhong W, Paunescu TG, Bouley R, Brown D

Sex-dependent differences in water homeostasis in wild-type and V-ATPase B1-subunit deficient mice.
PLoS ONE. 2019;14(8):e0219940 - PMID: 31386675 - PMCID: PMC6684071 - DOI: 10.1371/journal.pone.0219940

Chin LY, Carroll C, Raigani S, Detelich DM, Tessier SN, Wojtkiewicz GR, Schmidt SP, Weissleder R, Yeh H, Uygun K, Parekkadan B

Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs.
PLoS ONE. 2019;14(12):e0225222 - PMID: 31790444 - PMCID: PMC6886851 - DOI: 10.1371/journal.pone.0225222

Li R, Attari A, Prytyskach M, Garlin MA, Weissleder R, Miller MA

Single‐Cell Intravital Microscopy of Trastuzumab Quantifies Heterogeneous in vivo Kinetics
Cytometry A. 2019;97(5):528-539 - PMID: 31423731 - PMCID: PMC7028488 - DOI: 10.1002/cyto.a.23872

Marshansky V, Hosokawa H, Merkulova M, Bakulina A, Dip PV, Thaker YR, Bjargava A, Tonra JR, Ausiello DA, Grüber G

Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design.
Curr Top Membr. 2019;83:77-106 - PMID: 31196611 - DOI: 10.1016/bs.ctm.2019.01.008

Marquard AN, Carlson JCT, Weissleder R

Glass Chemistry to Analyze Human Cells under Adverse Conditions
ACS Omega. 2019;4:11515−11521 - PMID: 31460257 - PMCID: PMC6682085 - DOI: 10.1021/acsomega.9b01036

Zhao WN, Hylton NK, Wang J, Chindavong PS, Alural B, Kurtser I, Subramanian A, Mazitschek R, Perlis RH, Haggarty SJ

Activation of WNT and CREB signaling pathways in human neuronal cells in response to the Omega-3 fatty acid docosahexaenoic acid (DHA).
Mol Cell Neurosci. 2019;99:103386 - PMID: 31202891 - PMCID: PMC7001743 - DOI: 10.1016/j.mcn.2019.06.006

Ahrens CC, Chiswick EL, Ravindra KC, Miller MA, Ramseier J, Isaacson KB, Lauffenburger DA, Griffith LG

Development and Application of the Metalloprotease Activity Multi-plexed Bead-based Immunoassay (MAMBI).
Biochemistry. 2019;58(38):3938-3942 - PMID: 31474112 - DOI: 10.1021/acs.biochem.9b00584

Patil R, Tan X, Bartosik P, Detappe A, Runnels JM, Ghobrial I, Lin CP, Niedre M

Fluorescence monitoring of rare circulating tumor cell and cluster dissemination in a multiple myeloma xenograft model in vivo.
J Biomed Opt. 2019;24(8):1-11 - PMID: 31456386 - PMCID: PMC6983486 - DOI: 10.1117/1.JBO.24.8.085004

Sullivan R, Légaré C, Lamontagne-Proulx J, Breton S, Soulet D

Revisiting structure/functions of the human epididymis.
Andrology. 2019;7(5):748-757 - PMID: 31033221 - DOI: 10.1111/andr.12633

Breton S, Nair AV, Battistone MA

Epithelial dynamics in the epididymis: role in the maturation, protection, and storage of spermatozoa.
Andrology. 2019;7(5):631-643 - PMID: 31044554 - PMCID: PMC6688936 - DOI: 10.1111/andr.12632

Chulroek T, Kordbacheh H, Wangcharoenrung D, Cattapan K, Heidari P, Harisinghani MG

Comparative accuracy of qualitative and quantitative 18F-FDG PET/CT analysis in detection of lymph node metastasis from anal cancer.
Abdom Radiol (NY). 2019;44(3):828-835 - PMID: 30694369 - DOI: 10.1007/s00261-019-01907-6

Kordbacheh H, Baliyan V, Parakh A, Wojtkiewicz GR, Hedgire S, Harisinghani MG

Pictorial review on abdominal applications of ferumoxytol in MR imaging.
Abdom Radiol (NY). 2019;44(10):3273-3284 - PMID: 31378828 - DOI: 10.1007/s00261-019-02163-4

Liao HW, Garris C, Pfirschke C, Rickelt S, Arlauckas S, Siwicki M, Kohler RH, Weissleder R, Sundvold-Gjerstad V, Sveinbjørnsson B, Rekdal Ø, Pittet MJ

LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects.
Cell Stress. 2019;3(11):348-360 - PMID: 31799501 - PMCID: PMC6859426 - DOI: 10.15698/cst2019.11.204

Hansen S, Wood DK, Higgins JM

5-(Hydroxymethyl)furfural restores low-oxygen rheology of sickle trait blood in vitro.
Br J Haematol. 2019;188(6):985-993 - PMID: 31889311 - PMCID: PMC7150585 - DOI: 10.1111/bjh.16251

Bevill SM, Olivares-Quintero JF, Sciaky N, Golitz BT, Singh D, Beltran AS, Rashid NU, Stuhlmiller TJ, Hale A, Moorman NJ, Santos CM, Angus SP, Zawistowski JS, Johnson GL

GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer.
Mol Cancer Res. 2019;17(7):1503-1518 - PMID: 31000582 - PMCID: PMC6610760 - DOI: 10.1158/1541-7786.MCR-18-1121

Kim J, Lee SK, Schellingerhout D, Nahrendorf M, Kim K, Kim J, Kim DE

Spectroscopic Assessment of Gold Nanoparticle Biodistribution Using Surface Plasmon Resonance Phenomena.
ACS Biomater Sci Eng. 2019;5(12):6389-6394 - PMID: 33417791 - DOI: 10.1021/acsbiomaterials.9b01079

Banik G, Betts CB, Liudahl SM, Sivagnanam S, Kawashima R, Cotechini T, Larson W, Goecks J, Pai SI, Clayburgh DR, Tsujikawa T, Coussens LM

High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers.
Methods Enzymol. 2019;635:1-20 - PMID: 32122539 - PMCID: PMC7390987 - DOI: 10.1016/bs.mie.2019.05.039

Pai SI, Cohen EEW, Lin D, Fountzilas G, Kim ES, Mehlhorn H, Baste N, Clayburgh D, Lipworth L, Resteghini C, Shara N, Fujii T, Zhang J, Stokes M, Wang H, Twumasi-Ankrah P, Wildsmith S, Khaliq A, Melillo G, Shire N

SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.
J Transl Med. 2019;17(1):429 - PMID: 31878938 - PMCID: PMC6933901 - DOI: 10.1186/s12967-019-02182-1

Ishida E, Lee J, Campbell JS, Chakravarty PD, Katori Y, Ogawa T, Johnson L, Mukhopadhyay A, Faquin WC, Lin DT, Wirth LJ, Pierce RH, Pai SI

Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model.
Cancer Immunol Immunother. 2019;68(8):1273-1286 - PMID: 31243491 - PMCID: PMC6684362 - DOI: 10.1007/s00262-019-02357-1

Wolkow N, Jakobiec FA, Afrogheh AH, Eagle RC, Pai SI, Faquin WC

Programmed Cell Death 1 Ligand 1 and Programmed Cell Death 1 Ligand 2 Are Expressed in Conjunctival Invasive Squamous Cell Carcinoma: Therapeutic Implications.
Am J Ophthalmol. 2019;200:226-241 - PMID: 30633894 - PMCID: PMC7456462 - DOI: 10.1016/j.ajo.2018.12.020

Lamba N, Hwang WL, Kim DW, Niemierko A, Marciscano AE, Mehan WA, Benayoun MD, Curry WT, Barker FG, Martuza RL, Dunn IF, Claus E, Bi WL, Aizer AA, Alexander BM, Oh KS, Loeffler JS, Shih HA

Atypical Histopathological Features and the Risk of Treatment Failure in Nonmalignant Meningiomas: A Multi-Institutional Analysis.
World Neurosurg. 2019;133:e804-e812 - PMID: 31605839 - DOI: 10.1016/j.wneu.2019.10.002

Liu KX, Lamba N, Hwang WL, Niemierko A, DuBois SG, Haas-Kogan DA

Risk stratification by somatic mutation burden in Ewing sarcoma.
Cancer. 2019;125(8):1357-1364 - PMID: 30602061 - DOI: 10.1002/cncr.31919
127 CSV HTML