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Xie X, Zhang O, Yeo MJR, Lee C, Tao R, Harry SA, Payne NC, Nam E, Paul L, Li Y, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.
Nature. 2025;639(8053):241-249 - PMID: 39939763 - PMCID: PMC11882451 - DOI: 10.1038/s41586-024-08533-3
Yeo MJR, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Nguyen K, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Carr SA, Udeshi ND, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N
UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
Nature. 2025;639(8053):232-240 - PMID: 39939761 - PMCID: PMC11882444 - DOI: 10.1038/s41586-024-08532-4
Hricak H, Mayerhoefer ME, Herrmann K, Lewis JS, Pomper MG, Hess CP, Riklund K , Scott AM, Weissleder R
Advances and challenges in precision imaging
Lancet Oncol. 2025;26:e34-e45 - PMID: 39756454 - DOI: 10.1016/S1470-2045(24)00395-4
Blohmer M, Cheek DM, Hung WT, Kessler M, Chatzidimitriou F, Wang J, Hung W, Lee IH, Gorelick AN, Wassenaar EC, Yang CY, Yeh YC, Ho HL, Speiser D, Karsten MM, Lanuti M, Pai SI, Kranenburg O, Lennerz JK, Chou TY, Kloor M, Naxerova K
Quantifying cell divisions along evolutionary lineages in cancer.
Nat Genet. 2025;57(3):706-717 - PMID: 39905260 - DOI: 10.1038/s41588-025-02078-5
Grune J, Nahrendorf M
Response by Grune and Nahrendorf to Letter Regarding Article, "Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart".
Circulation. 2025;151(5):e35-e36 - PMID: 39899631 - DOI: 10.1161/CIRCULATIONAHA.124.072688
Kim HS, Simpson GG, Fei F, Garris C, Weissleder R
Fluorinated Ribonucleocarbohydrate Nanoparticles Allow Ultraefficient mRNA Delivery and Protein Expression in Tumor-Associated Myeloid Cells
J Am Chem Soc. 2025;147(14):11766-11776 - PMID: 40135499 - PMCID: PMC11987029 - DOI: 10.1021/jacs.4c14474
Foy BH, Carlson JCT, Aguirre AD, Higgins JM
Platelet-white cell ratio is more strongly associated with mortality than other common risk ratios derived from complete blood counts.
Nat Commun. 2025;16(1):1113 - PMID: 39875373 - PMCID: PMC11775293 - DOI: 10.1038/s41467-025-56251-9
Leming M, Kim K, Bruffaerts R, Im H
Strategies for mitigating data heterogeneities in AI-based neuro-disease detection.
Neuron. 2025;:ePub - PMID: 40037359 - DOI: 10.1016/j.neuron.2025.01.028
Parvanian S, Ge X, Garris CS
Recent developments in myeloid immune modulation in cancer therapy.
Trends Cancer. 2025;11(4):365-375 - PMID: 39794212 - DOI: 10.1016/j.trecan.2024.12.003
Choi Y, Park JH, Jo A, Lim CW, Park JM, Hwang JW, Lee KS, Kim YS, Lee H, Moon J
Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases.
Sci Adv. 2025;11(1):eado6894 - PMID: 39742488 - PMCID: PMC11691634 - DOI: 10.1126/sciadv.ado6894
Qin T, Mattox AK, Campbell JS, Park JC, Shin KY, Li S, Sadow PM, Faquin WC, Micevic G, Daniels AJ, Haddad R, Garris CS, Pittet MJ, Mempel TR, ONeill A, Sartor MA, Pai SI
Epigenetic therapy sensitizes anti-PD-1 refractory head and neck cancers to immunotherapy rechallenge.
J Clin Invest. 2025;135(6):ePub - PMID: 40091844 - PMCID: PMC11910227 - DOI: 10.1172/JCI181671
Wang C*, Jalali Motlagh N*, Wojtkiewicz GR, Yang H, Kim HH, Chen JW
A specific and adaptable approach to track CD206+ macrophages by molecular MRI and fluorescence imaging.
Theranostics. 2025;15(3):1094-1109 - PMID: 39776805 - PMCID: PMC11700851 - DOI: 10.7150/thno.96488
Cho YK, Choi Y, Kim S, Kim H, Chow KF, Shin IS, Park JH, Lee H
Scalable electrochemical system for rapid on-site detection of food allergens.
Biosens Bioelectron. 2025;273:117142 - PMID: 39832405 - PMCID: PMC11788024 - DOI: 10.1016/j.bios.2025.117142
Quintana JM*, Jiang F*, Kang M, Valladolid Onecha V, Könik A, Qin L, Rodriguez VE, Hu H, Borges N, Khurana I, Banla LI, Le Fur M, Caravan P, Schuemann J, Bertolet A, Weissleder R, Miller MA, Ng TSC
Localized In Vivo Prodrug Activation Using Radionuclides.
J Nucl Med. 2025;66(1):91-97 - PMID: 39753366 - PMCID: PMC11705795 - DOI: 10.2967/jnumed.124.268559
Konstantinopoulos PA, Cai M, Lee EK, Krasner C, Campos SM, Liu JF, Horowitz NS, Shea M, Parsons HA, Wright AA, Bouberhan S, Penson RT, Yeku O, Hayes M, Sawyer H, Polak M, Castro CM, Cheng SC, Weipert CM, Matulonis UA
Serial Circulating Tumor DNA Sequencing to Monitor Response and Define Acquired Resistance to Letrozole/Abemaciclib in Endometrial Cancer.
JCO Precis Oncol. 2025;9:e2400882 - PMID: 40209137 - DOI: 10.1200/PO-24-00882
Jaffe AT, Pallarès-López R, Raines JK, Aguirre AD, Anthony BW
Noninvasive Quantitative Compression Ultrasound Central Venous Pressure: A Clinical Pilot Study.
BME Front. 2025;6:0115 - PMID: 40110344 - PMCID: PMC11922486 - DOI: 10.34133/bmef.0115
Magudia K, Lee RS, Dibble EH, Parris D, Baniel CC, Beltran Ponce S, Laur O, Hamman S, Arleo EK, Johnstone C, Lightfoote J, Rubin E, Deitte L, Jagsi R, Kotsenas AL, Ng TSC
The State of Paid Family and Medical Leave Policies: An ACR, AAWR, SWRO Member Survey.
J Am Coll Radiol. 2025;:ePub - PMID: 40174871 - DOI: 10.1016/j.jacr.2025.03.006
Simerzin A, Ackerman EE, Fujimaki K, Kohler RH, Iwamoto Y, Heltberg MS, Jambhekar A, Weissleder R, Lahav G
Cell Confluency Affects p53 Dynamics in Response to DNA Damage.
Mol Biol Cell. 2025;:mbcE24090394 - PMID: 40202833 - DOI: 10.1091/mbc.E24-09-0394
Losee M, Kavanaugh M, Liu M, Borges N, Haberman V, Ritzer J, Wolanski A, Bhimaniya S, Choudhury AD, Hyun H, Stoltenberg H, Kilbridge KL, Morgans A, Pomerantz M, Robertson M, Sakellis C, Shah H, Taplin ME, Wei XX, Ng T, Ravi P, Jacene H
Outcome of Subsequent Therapies After 177Lu-Vipivotide Tetraxetan for Metastatic Castrate-Resistant Prostate Cancer: A Tertiary Cancer Center Experience.
Prostate. 2025;:ePub - PMID: 40103237 - DOI: 10.1002/pros.24880
Di Ianni E, Jeon J, Hu H, Quintana JM, Lee C, Haidar EA, Mohammadi S, Zargani-Piccardi A, Mahamdeh M, Hernández IC, Ng TSC, Breyne K, Lee H, Breakefield XO, Miller MA
Enhanced mRNA delivery using ultrasound-delivered click reactive anchors.
bioRxiv. 2025;:ePub - PMID: 39975219 - PMCID: PMC11838329 - DOI: 10.1101/2025.01.28.635330
Tozzo V, Petherbridge R, James K, Hsu S, Michalopoulos C, Foy BH, Thaweethai T, Mow C, Maya J, Camero CB, Shook L, Gray KJ, Mauney L, Higgins JM, Powe CE
Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study.
medRxiv. 2025;:ePub - PMID: 39990572 - PMCID: PMC11844592 - DOI: 10.1101/2025.02.13.25322250
Gong D, Liu R, Cui Y, Rhodes M, Bae JW, Beechem JM, Hwang WL
Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer.
bioRxiv. 2025;:ePub - PMID: 40161804 - PMCID: PMC11952565 - DOI: 10.1101/2025.03.12.642933
Szafraniec HM, Bull F, Higgins JM, Stone HA, Krüger T, Pearce P, Wood DK
Suspension physics govern the multiscale dynamics of blood flow in sickle cell disease.
bioRxiv. 2025;:ePub - PMID: 40161781 - PMCID: PMC11952557 - DOI: 10.1101/2025.03.13.642599
Lloyd HC, Li Y, Payne N, Zhao Z, Xu W, Kroupova A, Zollman D, Long T, Kabir F, Chen M, Freeman R, Feng EY, Xi S, Hsu YC, Ciulli A, Mazitschek R, Woo CM
A method for the detection and enrichment of endogenous cereblon substrates.
bioRxiv. 2025;:ePub - PMID: 40196695 - PMCID: PMC11974815 - DOI: 10.1101/2025.03.24.645063
Tozzo V, Zhang LH, Ranganath R, Higgins JM
Transformer-based artificial intelligence on single-cell clinical data for homeostatic mechanism inference and rational biomarker discovery.
medRxiv. 2025;:ePub - PMID: 40196278 - PMCID: PMC11974774 - DOI: 10.1101/2025.03.24.25324556
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