Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.
Distinct bone marrow blood vessels differentially regulate haematopoiesis.
Nature. 2016;532(7599):323-328 - PMID: 27074509
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation.
The role of myeloid cells in cancer therapies.
Nat Rev Cancer. 2016;16(7):447-62 - PMID: 27339708
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Cell. 2016;167(5):1310-1322.e17 - PMID: 27863245
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.
Single-molecule decoding of combinatorially modified nucleosomes.
SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
Gal3 Links Inflammation and Insulin Resistance.
Cell Metab. 2016;24(5):655-656 - PMID: 27829136
Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring
Sci Transl Med. 2016;8:359ra130 - PMID: 27708063
Taking cancer drug screening very personally.
Sci Transl Med. 2016;8(367):367ec190 - PMID: 27903858
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction
Imaging approaches to optimize molecular therapies
Sci Transl Med. 2016;8(355):355ps16 - PMID: 27605550
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.
Increased haematopoietic activity in patients with atherosclerosis.
Eur Heart J. 2016;38(6):425-432 - PMID: 27357356
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2016;:ePub - PMID: 26984866
Supramolecular Metallo-Bioadhesive for Minimally Invasive Use
Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum"
Light-controlled modulation of gene expression by chemical optoepigenetic probes.
Quantitating drug-target engagement in single cells in vitro and in vivo.
Nat Chem Biol. 2016;13(2):168-173 - PMID: 27918558
Imaging the pharmacology of nanomaterials by intravital microscopy: Towards understanding their biological behavior.
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.
Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
Bone Marrow Takes Center Stage in Cardiovascular Disease.
Abandoning M1/M2 for a Network Model of Macrophage Function.
Circadian Influence on Metabolism and Inflammation in Atherosclerosis.
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Using an Electronic Medical Records Database to Identify Non-Traditional Cardiovascular Risk Factors in Nonalcoholic Fatty Liver Disease.
Covalent Modulators of the Vacuolar ATPase.
Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma.
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells.
Real-time high dynamic range laser scanning microscopy.
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging.
ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease.
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.
In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.
Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway.
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Development and Function of Arterial and Cardiac Macrophages.
Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
J Am Soc Nephrol. 2016;:ePub - PMID: 26961350
Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an AE1 R607H Knockin Model.
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity.
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.
Glucagon-like peptide-1 receptor activation attenuates platelet aggregation and thrombosis.
Diabetes. 2016;65(6):1714-23 - PMID: 26936963
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer (NSCLC): A Retrospective Analysis.
Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.
Glycoengineering of E-selectin ligands by intracellular versus extracellular fucosylation differentially affects osteotropism of human mesenchymal stem cells.
Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood.
PF4 Promotes Platelet Production and Lung Cancer Growth.
APS Takes a Look in the Mirror.
Physiology (Bethesda). 2016;31(6):384-385 - PMID: 27708041
Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association.
Circ Cardiovasc Genet. 2016;9(2):193-202 - PMID: 26976545
Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
Statin use is Associated With Reduced Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases.
Fluorescent vinblastine probes for live cell imaging
The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.
Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.
Spinal Cord Inflammation: Molecular Imaging after Thoracic Aortic Ischemia Reperfusion Injury.
Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study.
Arterioscler Thromb Vasc Biol. 2016;36(11):2229-2238 - PMID: 27634834
E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial Infarction.
Macrophage IκB Kinase α Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.
Systems Biology and Noninvasive Imaging of Atherosclerosis.
Digital diffraction detection of protein markers for avian influenza.
Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.
Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome
Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles.
J Nucl Med. 2016;57(Suppl 3):105S-110S - PMID: 27694162
Intramolecular Diaza-Diels-Alder Protocol: A Novel Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.
Chemistry. 2016;23(17):4137-4148 - PMID: 27997727
MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.
A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever.
Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography.
Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response
Defining Clonal Color in Fluorescent Multi-Clonal Tracking
Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation.
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Biosens Bioelectron. 2016;81:408-14 - PMID: 26995287
Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis.
Use of Chronic Oral Anticoagulation and Associated Outcomes Among Patients Undergoing Percutaneous Coronary Intervention.
The SMAD pathway is required for hepcidin response during endoplasmic reticulum stress.
Activin B induces noncanonical SMAD1/5/8 signaling via BMP type I receptors in hepatocytes: evidence for a role in hepcidin induction by inflammation in male mice.
MenaINV mediates synergistic crosstalk between signaling pathways driving chemotaxis and haptotaxis.
Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo.
Eur Heart J Cardiovasc Imaging. 2016;:ePub - PMID: 28031233
Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.
Cell Signal. 2016;28(12):1842-1851 - PMID: 27575743
Two-Photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement
Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice.
Biol Reprod. 2016;94(4):78 - PMID: 26911425
Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains.
Myeloperoxidase inhibition increases neurogenesis after ischemic stroke.
Hepcidin regulation in the anemia of inflammation.
Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models.
Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.
CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.
Molecular Order of Arterial Collagen Using Circular Polarization Second-Harmonic Generation Imaging.
Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension.
ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway.
Ironing out the crosstalk between FGF23 and inflammation.
Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles
Intravital multiphoton photoconversion with a cell membrane dye.
J Biophotonics. 2016;10(2):206-210 - PMID: 27433967
Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
ChemMedChem. 2016;11(19):2194-2204 - PMID: 27538856
The Use of Smartphones for Health Research.
Acad Med. 2016;92(2):157-160 - PMID: 27119325
The expression patterns of aquaporin 9, vacuolar H(+)-ATPase, and cytokeratin 5 in the epididymis of the common vampire bat.
Histochem Cell Biol. 2016;147(1):39-48 - PMID: 27549752
Fluorescent substrates for ADAM15 useful for assaying and high throughput screening.
Anal Biochem. 2016;514:42-47 - PMID: 27637923
Distinguishing hemangiomas from metastases on liver MRI performed with gadoxetate disodium: Value of the extended washout sign.
Eur J Radiol. 2016;85(3):635-40 - PMID: 26860678
Inflammatory bowel disease imaging: Current practice and future directions.
Varying levels of small microcalcifications and macrophages in ATTR and AL cardiac amyloidosis: implications for utilizing nuclear medicine studies to subtype amyloidosis.
Cardiovasc Pathol. 2016;25(5):413-417 - PMID: 27469499
The impact of splenectomy on human coronary artery atherosclerosis and vascular macrophage distribution.
Cardiovasc Pathol. 2016;25(6):453-460 - PMID: 27614166
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria.
Cardiovasc Pathol. 2016;25(3):247-257 - PMID: 27031798
Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.
Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2-HO-1 pathway in renal proximal tubular cells of transgenic mice.
J Renin Angiotensin Aldosterone Syst. 2016;17(3):ePub - PMID: 27638854
Extranodal lymphomas of abdomen and pelvis: imaging findings and differential diagnosis.
Abdom Radiol. 2016;42(4):1096-1112 - PMID: 27866240
Prediction of 5-year survival in advanced-stage ovarian cancer patients based on computed tomography peritoneal carcinomatosis index.
Abdom Radiol. 2016;41(11):2196-2202 - PMID: 27338731
Prostate imaging reporting and data system version 2 (PI-RADS v2): a pictorial review.
Imaging on nodal staging of prostate cancer.
Future Oncol. 2016;13(6):551-565 - PMID: 27785926
Endotracheal Tubes Cleaned With a Novel Mechanism for Secretion Removal: A Randomized Controlled Clinical Study.
Respir Care. 2016;61(11):1431-1439 - PMID: 27460104
Corneal Crosslinking With Rose Bengal and Green Light: Efficacy and Safety Evaluation.
Cornea. 2016;35(9):1234-41 - PMID: 27362877
Reliability of body size measurements obtained at autopsy: impact on the pathologic assessment of the heart.
Forensic Sci Med Pathol. 2016;12(2):139-45 - PMID: 27020890
Association between Serum Lipid Profiles and Early Neurological Deterioration in Acute Ischemic Stroke.
J Stroke Cerebrovasc Dis. 2016;25(8):2024-30 - PMID: 27256172
Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study.
Large vessel involvement by IgG4-related disease.
Direct Thrombus Imaging in Stroke.
Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system
Inflammation: a trigger for acute coronary syndrome.
Q J Nucl Med Mol Imaging. 2016;60(3):185-193 - PMID: 27273431
Challenges influencing next generation technologies for precision medicine.
Mechanisms of Myeloid Cell Modulation of Atherosclerosis.
Microbiol Spectr. 2016;4(4):ePub - PMID: 27726819
Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group.
Two-photon imaging of pancreatic beta cells in real time in vivo