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Baggett MV, Turbett SE, Schwartzenberg SS, Stone JR
Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure.
New Engl J Med. 2014;370(7):651-60 - PMID: 24521112 - DOI: 10.1056/NEJMcpc1310004
Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, Kinnunen L, Koistinen HA, Ladenvall C, Getz G, Correa A, Banahan BF, Gabriel S, Kathiresan S, Stringham HM, McCarthy MI, Boehnke M, Tuomilehto J, Haiman C, Groop L, Atzmon G, Wilson JG, Neuberg D, Altshuler D, Ebert BL
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.
New Engl J Med. 2014;371(26):2488-2498 - PMID: 25426837 - PMCID: PMC4306669 - DOI: 10.1056/NEJMoa1408617
Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP
Direct measurement of local oxygen concentration in the bone marrow of live animals.
Nature. 2014;508(7495):269-73 - PMID: 24590072 - PMCID: PMC3984353 - DOI: 10.1038/nature13034
Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE
Genetic and epigenetic fine mapping of causal autoimmune disease variants.
Nature. 2014;518(7539):337-43 - PMID: 25363779 - PMCID: PMC4336207 - DOI: 10.1038/nature13835
Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov AM, Epstein C, Rinn JL, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A
Dissecting neural differentiation regulatory networks through epigenetic footprinting.
Nature. 2014;518(7539):355-9 - PMID: 25533951 - PMCID: PMC4336237 - DOI: 10.1038/nature13990
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY
ABCB5 is a limbal stem cell gene required for corneal development and repair.
Nature. 2014;511(7509):353-7 - PMID: 25030174 - PMCID: PMC4246512 - DOI: 10.1038/nature13426
Weissleder R, Nahrendorf M, Pittet MJ
Imaging macrophages with nanoparticles.
Nat Mater. 2014;13(2):125-38 - PMID: 24452356 - DOI: 10.1038/nmat3780 - Cover
Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Nat Genet. 2014;46(4):364-70 - PMID: 24584072 - PMCID: PMC4086945 - DOI: 10.1038/ng.2913
Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H*
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947 - DOI: 10.1038/nbt.2886
Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
Cell. 2014;158(5):1110-22 - PMID: 25171411 - PMCID: PMC4149753 - DOI: 10.1016/j.cell.2014.07.013
Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells.
Cell. 2014;157(3):580-94 - PMID: 24726434 - PMCID: PMC4004670 - DOI: 10.1016/j.cell.2014.02.030
Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AK, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Panigrahy D, Schroeder A, Kotelianski V, Langer R, Anderson DG
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
Nat Nanotechnol. 2014;9(8):648-55 - PMID: 24813696 - PMCID: PMC4207430 - DOI: 10.1038/nnano.2014.84
Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL
Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors.
Science. 2014;344(6184):630-4 - PMID: 24797482 - PMCID: PMC4123747 - DOI: 10.1126/science.1251141
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.
Science. 2014;344(6190):1396-401 - PMID: 24925914 - PMCID: PMC4123637 - DOI: 10.1126/science.1254257
Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M
Chronic variable stress activates hematopoietic stem cells
Nature Med. 2014;20(7):754-758 - PMID: 24952646 - PMCID: PMC4087061 - DOI: 10.1038/nm.3589
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN
EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma.
Cancer Cell. 2014;26(5):668-81 - PMID: 25453903 - PMCID: PMC4492343 - DOI: 10.1016/j.ccell.2014.10.004
Mulder WJ, Jaffer FA, Fayad ZA, Nahrendorf M
Imaging and Nanomedicine in Inflammatory Atherosclerosis.
Sci Transl Med. 2014;6(239):239sr1 - PMID: 24898749 - PMCID: PMC4110972 - DOI: 10.1126/scitranslmed.3005101 - Cover
Kobzik L, Swirski FK
MARCOing Monocytes for Elimination.
Sci Transl Med. 2014;6(219):219fs4 - PMID: 24431109 - PMCID: PMC4374341 - DOI: 10.1126/scitranslmed.3008448
Ullal AV*, Peterson V*, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R
Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates
Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113 - PMCID: PMC4063286 - DOI: 10.1126/scitranslmed.3007361
Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R
Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin
Sci Transl Med. 2014;6 (261):261ra152 - PMID: 25378644 - PMCID: PMC4330962 - DOI: 10.1126/scitranslmed.3009318
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Nat Neurosci. 2014;17(9):1156-1163 - PMID: 25129075 - PMCID: PMC4292795 - DOI: 10.1038/nn.3786
Kroll MW, Lakkireddy DR, Stone JR, Luceri RM
TASER Electronic Control Devices and Cardiac Arrests: Coincidental or Causal?
Circulation. 2014;129(1):93-100 - PMID: 24396012 - DOI: 10.1161/CIRCULATIONAHA.113.004401
Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity.
Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655 - DOI: 10.1161/CIRCULATIONAHA.113.006381
Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA
FDG-PET/CT Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus.
Circulation. 2014;130(13):1044-52 - PMID: 25070665 - PMCID: PMC4174982 - DOI: 10.1161/CIRCULATIONAHA.114.008902
Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M
Silencing of CCR2 in myocarditis.
Eur Heart J. 2014;36(23):1478-88 - PMID: 24950695 - PMCID: PMC4465633 - DOI: 10.1093/eurheartj/ehu225
Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ
Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study.
Eur Heart J. 2014;35(42):2972-9 - PMID: 24742886 - PMCID: PMC4223610 - DOI: 10.1093/eurheartj/ehu153
Attanasio C, Nord AS, Zhu Y, Blow MJ, Biddie SC, Mendenhall EM, Dixon J, Wright CA, Hosseini R, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Afzal V, Ren B, Bernstein B, Rubin E, Visel A, Pennacchio L
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.
Genome Res. 2014;24(6):920-9 - PMID: 24752179 - PMCID: PMC4032856 - DOI: 10.1101/gr.168930.113
Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
J Exp Med. 2014;211(6):1243-56 - PMID: 24821911 - PMCID: PMC4042649 - DOI: 10.1084/jem.20131471
Taqueti VR, Nahrendorf M, Di Carli MF
Translational molecular imaging: repurposing an old technique to track cell migration into human atheroma.
J Am Coll Cardiol. 2014;64(10):1030-2 - PMID: 25190239 - DOI: 10.1016/j.jacc.2014.07.004
Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R
Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging.
Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131 - DOI: 10.1002/anie.201403890
Dutta P, Nahrendorf M
Regulation and consequences of monocytosis.
Immunol Rev. 2014;262(1):167-78 - PMID: 25319334 - PMCID: PMC4203415 - DOI: 10.1111/imr.12219
Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire C, Chen JW, Tannous BA, Breakefield XO
Dynamic Biodistribution of Extracellular Vesicles In Vivo Using a Multimodal Imaging Reporter.
ACS Nano. 2014;8(1):483-94 - PMID: 24383518 - PMCID: PMC3934350 - DOI: 10.1021/nn404945r
Heidt T, Courties G, Dutta P, Sager H, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M
Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction.
Circ Res. 2014;115(2):284-95 - PMID: 24786973 - PMCID: PMC4082439 - DOI: 10.1161/CIRCRESAHA.115.303567
Swirski FK, Nahrendorf M
Do vascular smooth muscle cells differentiate to macrophages in atherosclerotic lesions?
Circ Res. 2014;115(7):605-6 - PMID: 25214571 - PMCID: PMC4166538 - DOI: 10.1161/CIRCRESAHA.114.304925
Nahrendorf M, Swirski FK
Regulating repair: regulatory T cells in myocardial infarction.
Circ Res. 2014;115(1):7-9 - PMID: 24951758 - PMCID: PMC4094354 - DOI: 10.1161/CIRCRESAHA.114.304295
Nahrendorf M, Swirski FK
Fluorescent leukocytes enter plaque on the microscope stage.
Circ Res. 2014;114(5):740-1 - PMID: 24577957 - PMCID: PMC3957183 - DOI: 10.1161/CIRCRESAHA.114.303520
Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherrer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium.
Circ Res. 2014;114(10):1611-22 - PMID: 24625784 - PMCID: PMC4017349 - DOI: 10.1161/CIRCRESAHA.114.303204
Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF
A genomic and evolutionary approach reveals non-genetic drug resistance in malaria.
Genome Biol. 2014;15(11):511 - PMID: 25395010 - PMCID: PMC4272547 - DOI: 10.1186/PREACCEPT-1067113631444973
Eda H, Santo L, Cirstea DD, Yee AJ, Scullen TA, Nemani N, Mishima Y, Waterman PR, Arastu-Kapur S, Evans E, Singh J, Kirk CJ, Westlin WF, Raje NS
A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
Leukemia. 2014;28(9):1892-901 - PMID: 24518207 - DOI: 10.1038/leu.2014.69
Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, Yuan J, Ware C, MacLean J, Garrett-Engele PW, Kluk M, Laskey J, Haines BB, Moskaluk C, Zawel L, Fawell S, Gilliland G, Zhang T, Kremer B, Knoechel B, Bernstein BE, Pear WS, Liu XS, Aster JC, Sathyanarayanan S
Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma.
Cancer Discov. 2014;4(10):1154-67 - PMID: 25104330 - PMCID: PMC4184927 - DOI: 10.1158/2159-8290.CD-13-0830
Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B
Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.
Nat Commun. 2014;5:5662 - PMID: 25489927 - PMCID: PMC4261930 - DOI: 10.1038/ncomms6662
Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R
In vivo imaging of specific drug-target binding at subcellular resolution.
Nat Commun. 2014;5:3946 - PMID: 24867710 - PMCID: PMC4362617 - DOI: 10.1038/ncomms4946
Lee SK, Mortensen LJ, Lin CP, Tung CH
An authentic imaging probe to track cell fate from beginning to end.
Nat Commun. 2014;5:5216 - PMID: 25323442 - PMCID: PMC4852472 - DOI: 10.1038/ncomms6216
Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation.
Nat Commun. 2014;5:3065 - PMID: 24445279 - PMCID: PMC4001802 - DOI: 10.1038/ncomms4065
Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut.
Proc Natl Acad Sci U S A. 2014;111(18):6696-701 - PMID: 24753589 - PMCID: PMC4020091 - DOI: 10.1073/pnas.1405634111
Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
Proc Natl Acad Sci U S A. 2014;111(46):E4946-53 - PMID: 25369933 - PMCID: PMC4246292 - DOI: 10.1073/pnas.1407079111
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC
Defining functional DNA elements in the human genome.
Proc Natl Acad Sci U S A. 2014;111(17):6131-6138 - PMID: 24753594 - PMCID: PMC4035993 - DOI: 10.1073/pnas.1318948111
Naxerova K, Brachtel E, Salk JJ, Seese AM, Power K, Abbasi B, Snuderl M, Chiang S, Kasif S, Jain RK
Hypermutable DNA chronicles the evolution of human colon cancer.
Proc Natl Acad Sci U S A. 2014;111(18):E1889-98 - PMID: 24753616 - PMCID: PMC4020055 - DOI: 10.1073/pnas.1400179111
Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D
Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature.
Proc Natl Acad Sci U S A. 2014;111(31):11419-24 - PMID: 25049388 - PMCID: PMC4128122 - DOI: 10.1073/pnas.1410854111
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC
Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease.
Proc Natl Acad Sci U S A. 2014;111(33):E3366 - PMID: 25275169 - PMCID: PMC4143047
Aguirre AD, Vinegoni C, Sebas M, Weissleder R
Intravital imaging of cardiac function at the single-cell level.
Proc Natl Acad Sci U S A. 2014;111(31):11257-62 - PMID: 25053815 - PMCID: PMC4128110 - DOI: 10.1073/pnas.1401316111
Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D
Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
eLife. 2014;3:e04631 - PMID: 25407682 - PMCID: PMC4270084 - DOI: 10.7554/eLife.04631 - Cover
Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Del Toro R, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192 - DOI: 10.1182/blood-2014-08-593426
Babitt JL, Lin HY
BuMPing iron with modified heparins.
Blood. 2014;123(10):1440-1 - PMID: 24627550 - PMCID: PMC3945857 - DOI: 10.1182/blood-2014-01-549519
Yoon YI, Kwon YS, Cho HS, Heo SH, Park KS, Park SG, Lee SH, Hwang SI, Kim YI, Jae HJ, Ahn GJ, Cho YS, Lee H*, Lee HJ*, Yoon TJ*
Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System
Theranostics. 2014;4(11):1133-1144
Chan CT, Qi J, Smith W, Paranal R, Mazitschek R, West N, Reeves R, Chiosis G, Schreiber SL, Bradner JE, Paulmurugan R, Gambhir SS
Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase (HDAC) Inhibitors by Multimodality Molecular Imaging in Living Subjects.
Cancer Res. 2014;74(24):7475-86 - PMID: 25320008 - PMCID: PMC4315624 - DOI: 10.1158/0008-5472.CAN-14-0197
Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L
Harnessing the Intestinal Microbiome for Optimal Therapeutic Immunomodulation.
Cancer Res. 2014;74(16):4217-4221 - PMID: 25074615 - DOI: 10.1158/0008-5472.CAN-14-0987
Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L
Gut microbiome and anticancer immune response: really hot Sh*t!
Cell Death Differ. 2014;22(2):199-214 - PMID: 24832470 - PMCID: PMC4291500 - DOI: 10.1038/cdd.2014.56
Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Desphande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman JA, Bardeesy N
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer.
Clin Cancer Res. 2014;21(2):396-404 - PMID: 25348516 - PMCID: PMC4447091 - DOI: 10.1158/1078-0432.CCR-14-1591
Teo GS, Yang Z, Carman CV, Karp JM, Lin CP
Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association with Platelets and Neutrophils.
Stem Cells. 2014;33(1):265-277 - PMID: 25263183 - PMCID: PMC4270897 - DOI: 10.1002/stem.1848
Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.
Sci Signal. 2014;7(348):ra100 - PMID: 25336613 - PMCID: PMC4300109 - DOI: 10.1126/scisignal.2005262
Ghazani A, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R
Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance.
Nanomedicine. 2014;10 :661-668 - PMID: 24200523 - PMCID: PMC3966960 - DOI: 10.1016/j.nano.2013.10.008
Aranda F, Bloy N, Pesquet J, Petit B, Chaba K, Sauvat A, Kepp O, Khadra N, Enot D, Pfirschke C, Pittet M, Zitvogel L, Kroemer G, Senovilla L
Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer.
Oncogene. 2014;34(23):3053-62 - PMID: 25065595 - DOI: 10.1038/onc.2014.234
Lan YY, Londoño D, Bouley R, Rooney MS, Hacohen N
Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy.
Cell Rep. 2014;9(1):180-92 - PMID: 25284779 - PMCID: PMC4555847 - DOI: 10.1016/j.celrep.2014.08.074
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2014;12(8):1342-1348.e1 - PMID: 24407106 - PMCID: PMC4085150 - DOI: 10.1016/j.cgh.2013.12.030
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2014;13(2):322-329.e1 - PMID: 25041865 - PMCID: PMC4297589 - DOI: 10.1016/j.cgh.2014.07.018
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases.
Clin Gastroenterol Hepatol. 2014;12(11):1905-1910 - PMID: 24632349 - PMCID: PMC4162859 - DOI: 10.1016/j.cgh.2014.02.034
Castro CM, Im H, Le C, Lee H, Weissleder R, Birrer MJ
Exploring alternative ovarian cancer biomarkers using innovative nanotechnology strategies.
Cancer Metastasis Rev. 2014;34(1):75-82 - PMID: 25543192 - PMCID: PMC5474936 - DOI: 10.1007/s10555-014-9546-9
Pulli B, Bure L, Wojtkiewicz GR, Iwamoto Y, Ali M, Li D, Schob S, Li-Chun Hsieh K, Jacobs AH, Chen JW
Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model.
Radiology. 2014;:141495 - PMID: 25494298 - PMCID: PMC4455671 - DOI: 10.1148/radiol.14141495
Hilgendorf I, Swirski FK, Robbins CS
Monocyte Fate in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2014;35(2):272-9 - PMID: 25538208 - DOI: 10.1161/ATVBAHA.114.303565
Kim E, Yang KS, Giedt RJ, Weissleder R
Red Si-rhodamine drug conjugates enable imaging in GFP cells.
Chem Commun. 2014;50(34):4504-7 - PMID: 24663433 - PMCID: PMC4028821 - DOI: 10.1039/c4cc00144c
Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A
Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.
JACC Cardiovasc Imaging. 2014;8(2):121-30 - PMID: 25577441 - DOI: 10.1016/j.jcmg.2014.10.009
Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R*, Lee H*
Magnetic sensing technology for molecular analyses.
Lab Chip. 2014;14(14):2385-97 - PMID: 24887807 - PMCID: PMC4098149 - DOI: 10.1039/c4lc00314d
Frantz S, Nahrendorf M
Cardiac macrophages and their role in ischemic heart disease.
Cardiovasc Res. 2014;102(2):240-8 - PMID: 24501331 - PMCID: PMC3989449 - DOI: 10.1093/cvr/cvu025
Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway.
J Cell Sci. 2014;127(Pt 20):4396-408 - PMID: 25107366 - PMCID: PMC4197086 - DOI: 10.1242/jcs.148098 - Cover
Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R*
Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040 - DOI: 10.1002/adhm.201300672
Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P
Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata.
Circ Cardiovasc Imaging. 2014;7(6):920-929 - PMID: 25170063 - PMCID: PMC4237630 - DOI: 10.1161/CIRCIMAGING.114.002113
Nahrendorf M, Swirski FK
Imaging systemic inflammation in patients with acute myocardial infarction.
Circ Cardiovasc Imaging. 2014;7(5):762-4 - PMID: 25227235 - DOI: 10.1161/CIRCIMAGING.114.002410
Roussakis E, Spencer JA, Lin CP, Vinogradov SA
Two-Photon Antenna-Core Oxygen Probe with Enhanced Performance.
Anal Chem. 2014;86(12):5937-45 - PMID: 24848643 - PMCID: PMC4066907 - DOI: 10.1021/ac501028m
Thurber G, Reiner T, Yang K, Kohler R, Weissleder R
Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors.
Mol Cancer Ther. 2014;13(4):986-95 - PMID: 24552776 - PMCID: PMC3981972 - DOI: 10.1158/1535-7163.MCT-13-0801
Lee S, Vinegoni C, Sebas M, Weissleder R
Automated motion artifact removal for intravital microscopy, without a priori information.
Sci Rep. 2014;4:4507 - PMID: 24676021 - PMCID: PMC3968488 - DOI: 10.1038/srep04507
Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R
Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.
Sci Rep. 2014;4:4782 - PMID: 24759210 - PMCID: PMC3998017 - DOI: 10.1038/srep04782
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S
Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity.
ACS Chem Biol. 2014;9(4):1061 - PMID: 22724584 - DOI: 10.1021/cb300235m
Forghani R, Kim HJ, Wojtkiewicz GR, Bure L, Wu Y, Hayase M, Wei Y, Zheng Y, Moskowitz MA, Chen JW
Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke.
J Cereb Blood Flow Metab. 2014;35(3):485-93 - PMID: 25515211 - PMCID: PMC4348390 - DOI: 10.1038/jcbfm.2014.222
Swirski FK, Hilgendorf I, Robbins CS
From proliferation to proliferation: monocyte lineage comes full circle.
Semin Immunopathol. 2014;36(2):137-48 - PMID: 24435095 - PMCID: PMC3991755 - DOI: 10.1007/s00281-013-0409-1
Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes.
Mol Cell Biol. 2014;34(14):2773 - PMID: 24951669 - PMCID: PMC4097671
Malka R, Delgado FF, Manalis SR, Higgins JM
In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells.
PLoS Comput Biol. 2014;10(10):e1003839 - PMID: 25299941 - PMCID: PMC4191880 - DOI: 10.1371/journal.pcbi.1003839
Xu Y, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW
The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis.
J Lipid Res. 2014;56(2):266-76 - PMID: 25528754 - PMCID: PMC4306681 - DOI: 10.1194/jlr.M053017
Jun HJ, Roy J, Smith TB, Wood LB, Lane K, Woolfenden S, Punko D, Bronson RT, Haigis KM, Breton S, Charest A
ROS1 Signaling Regulates Epithelial Differentiation in the Epididymis.
Endocrinology. 2014;:en20141341 - PMID: 24971615 - PMCID: PMC4138574 - DOI: 10.1210/en.2014-1341
Zumbrennen-Bullough K, Wu Q, Core AB, Canali S, Chen W, Theurl I, Meynard D, Babitt JL
MicroRNA-130a is upregulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription.
J Biol Chem. 2014;289(34):23796-808 - PMID: 25002578 - PMCID: PMC4156078 - DOI: 10.1074/jbc.M114.577387
Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T
Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.
Hum Genet. 2014;133(11):1369-82 - PMID: 25062868 - PMCID: PMC4185241 - DOI: 10.1007/s00439-014-1466-9
Sprachman M, Laughney A, Kohler R, Weissleder R
In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor.
Bioconjug Chem. 2014;25(6):1137-42 - PMID: 24806886 - PMCID: PMC4098115 - DOI: 10.1021/bc500154c
Giedt RJ, Sprachman M, Yang K, Weissleder R
Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates.
Bioconjug Chem. 2014;25(11):2081-2085 - PMID: 25333750 - PMCID: PMC4240345 - DOI: 10.1021/bc500433k
Brand C, Abdel-Atti D, Zhang Y, Carlin S, Clardy SM, Keliher EJ, Weber WA, Lewis JS, Reiner T
In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent.
Bioconjug Chem. 2014;25(7):1323-30 - PMID: 24856928 - PMCID: PMC4215873 - DOI: 10.1021/bc500178d
Courtis AM, Santos SA, Guan Y, Hendricks JA, Ghosh B, Szantai-Kis DM, Reis SA, Shah JV, Mazitschek R
Monoalkoxy BODIPYs - A Fluorophore Class for Bioimaging.
Bioconjug Chem. 2014;25(6):1043-51 - PMID: 24797834 - PMCID: PMC4215867 - DOI: 10.1021/bc400575w
Marshansky V, Rubinstein JL, Grüber G
Eukaryotic V-ATPase: Novel Structural Findings and Functional Insights.
Biochim Biophys Acta. 2014;1837(6):857-879 - PMID: 24508215 - DOI: 10.1016/j.bbabio.2014.01.018
Păunescu TG, Shum WW, Huynh C, Lechner L, Goetze B, Brown D, Breton S
High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa.
Mol Hum Reprod. 2014;20(10):929-37 - PMID: 25015675 - PMCID: PMC4172170 - DOI: 10.1093/molehr/gau052
Pittet MJ, Nahrendorf M, Swirski FK
The journey from stem cell to macrophage.
Ann N Y Acad Sci. 2014;1319(1):1-18 - PMID: 24673186 - PMCID: PMC4074243 - DOI: 10.1111/nyas.12393
Michot C, Le Goff C, Mahaut C, Afenjar A, Brooks AS, Campeau PM, Destree A, Di Rocco M, Donnai D, Hennekam R, Heron D, Jacquemont S, Kannu P, Lin AE, Manouvrier-Hanu S, Mansour S, Marlin S, McGowan R, Murphy H, Raas-Rothschild A, Rio M, Simon M, Stolte-Dijkstra I, Stone JR, Sznajer Y, Tolmie J, Touraine R, van den Ende J, Van der Aa N, van Essen T, Verloes A, Munnich A, Cormier-Daire V
Myhre and LAPS syndromes: clinical and molecular review of 32 patients.
Eur J Hum Genet. 2014;22(11):1272-7 - PMID: 24424121 - PMCID: PMC4200423 - DOI: 10.1038/ejhg.2013.288
Vinegoni C, Lee S, Feruglio PF, Weissleder R
Advanced Motion Compensation Methods for Intravital Optical Microscopy.
IEEE J Sel Top Quantum Electron. 2014;20(2):ePub - PMID: 24273405 - PMCID: PMC3832946 - DOI: 10.1109/JSTQE.2013.2279314
Kim B, Roy J, Shum WW, Da Silva N, Breton S
Role of Testicular Luminal Factors on Basal Cell Elongation and Proliferation in the Mouse Epididymis.
Biol Reprod. 2014;92(1):9 - PMID: 25411392 - PMCID: PMC4434934 - DOI: 10.1095/biolreprod.114.123943
Shum WW, Smith TB, Cortez-Retamozo V, Grigoryeva LS, Roy JW, Hill E, Pittet MJ, Breton S, Da Silva N
Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis.
Biol Reprod. 2014;90(5):90 - PMID: 24648397 - PMCID: PMC4076373 - DOI: 10.1095/biolreprod.113.116681
Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG
Hereditary xerocytosis revisited.
Am J Hematol. 2014;89(12):1142-1146 - PMID: 25044010 - PMCID: PMC4237618 - DOI: 10.1002/ajh.23799
Golub MS, Hogrefe CE, Malka R, Higgins JM
Developmental Plasticity of red blood cell homeostasis.
Am J Hematol. 2014;89(5):459-66 - PMID: 24415575 - PMCID: PMC4086753 - DOI: 10.1002/ajh.23666
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J
Chemical Interrogation of the Malaria Kinome.
Chembiochem. 2014;15(13):1920-30 - PMID: 25111632 - PMCID: PMC4237307 - DOI: 10.1002/cbic.201400025 - Cover
Elman JS, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B
Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells.
PLoS ONE. 2014;9(2):e89882 - PMID: 24587097 - PMCID: PMC3931832 - DOI: 10.1371/journal.pone.0089882
Hsieh LC, Chen JW, Wang LY, Tsang YM, Shueng PW, Liao LJ, Lo WC, Lin YC, Tseng CF, Kuo YS, Jhuang JY, Tien HJ, Juan HF, Hsieh CH
Predicting the severity and prognosis of trismus after intensity-modulated radiation therapy for oral cancer patients by magnetic resonance imaging.
PLoS ONE. 2014;9(3):e92561 - PMID: 24658376 - PMCID: PMC3962418 - DOI: 10.1371/journal.pone.0092561
Mehan WA, González RG, Buchbinder BR, Chen JW, Copen WA, Gupta R, Hirsch JA, Hunter GJ, Hunter S, Johnson JM, Kelly HR, Larvie M, Lev MH, Pomerantz SR, Rapalino O, Rincon S, Romero JM, Schaefer PW, Shah V
Optimal Brain MRI Protocol for New Neurological Complaint.
PLoS ONE. 2014;9(10):e110803 - PMID: 25343371 - PMCID: PMC4208779 - DOI: 10.1371/journal.pone.0110803
Miranda KC, Bond DT, Levin JZ, Adiconis X, Sivachenko A, Russ C, Brown D, Nusbaum C, Russo LM
Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA.
PLoS ONE. 2014;9(5):e96094 - PMID: 24816817 - PMCID: PMC4015934 - DOI: 10.1371/journal.pone.0096094
Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM
Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume.
Cytometry A. 2014;85(4):332-8 - PMID: 24677669 - PMCID: PMC4717472 - DOI: 10.1002/cyto.a.22450
Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D
High throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration.
Am J Physiol Cell Physiol. 2014;307(7):C597-605 - PMID: 24944200 - PMCID: PMC4187055 - DOI: 10.1152/ajpcell.00154.2014
Chow MJ, Turcotte R, Lin CP, Zhang Y
Arterial Extracellular Matrix: A Mechanobiological Study of the Contributions and Interactions of Elastin and Collagen.
Biophys J. 2014;106(12):2684-2692 - PMID: 24940786 - PMCID: PMC4070071 - DOI: 10.1016/j.bpj.2014.05.014
Hedgire SS, Mino-Kenudson M, Elmi A, Thayer S, Fernandez-Del Castillo C, Harisinghani MG
Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation.
Int J Nanomedicine. 2014;9:1891-1896 - PMID: 24790431 - PMCID: PMC4000182 - DOI: 10.2147/IJN.S59788
Kim KM, Cambria RP, Isselbacher EM, Baker JN, LaMuraglia GM, Stone JR, MacGillivray TE
Contemporary Surgical Approaches and Outcomes in Adults With Kommerell Diverticulum.
Ann Thorac Surg. 2014;98(4):1347-1354 - PMID: 25134861 - DOI: 10.1016/j.athoracsur.2014.05.045
Alt C, Runnels JM, Mortensen LJ, Zaher W, Lin C
In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment.
Invest Ophthalmol Vis Sci. 2014;55(8):5314-5319 - PMID: 25082884 - DOI: 10.1167/iovs.14-14254
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.
J Crohns Colitis. 2014;8(9):956-63 - PMID: 24559536 - PMCID: PMC4136996 - DOI: 10.1016/j.crohns.2014.01.019
Dubach JM, Vinegoni C, Weissleder R
Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging.
Opt Lett. 2014;39(15):4482-4485 - PMID: 25078208 - PMCID: PMC4341989
Smith TB, Cortez-Retamozo V, Grigoryeva LS, Hill E, Pittet MJ, Da Silva N
Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis.
Andrology. 2014;2(5):755-62 - PMID: 25082073 - PMCID: PMC4396827 - DOI: 10.1111/j.2047-2927.2014.00251.x - Cover
Mortensen LJ, Alt C, Turcotte R, Masek M, Liu TM, Côté DC, Xu C, Intini G, Lin CP
Femtosecond laser bone ablation with a high repetition rate fiber laser source.
Biomed Opt Express. 2014;6(1):32-42 - PMID: 25657872 - PMCID: PMC4317121 - DOI: 10.1364/BOE.6.000032
Turcotte R, Alt C, Mortensen LJ, Lin CP
Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy.
Biomed Opt Express. 2014;5(10):3578-88 - PMID: 25360374 - PMCID: PMC4206326 - DOI: 10.1364/BOE.5.003578
Pulli B, Chen JW
Imaging Neuroinflammation - from Bench to Bedside.
J Clin Cell Immunol. 2014;5:ePub - PMID: 25525560 - PMCID: PMC4266918 - DOI: 10.4172/2155-9899.1000226
Wu JW, Runnels JM, Lin CP
Intravital imaging of hematopoietic stem cells in the mouse skull.
Methods Mol Biol. 2014;1185:247-65 - PMID: 25062634 - DOI: 10.1007/978-1-4939-1133-2_17
Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R
Platinum Compounds for High-Resolution In Vivo Cancer Imaging.
ChemMedChem. 2014;9(6):1131-5 - PMID: 24504646 - PMCID: PMC4037345 - DOI: 10.1002/cmdc.201300502
Keliher EJ, Klubnick JA Reiner T, Mazitschek R, Weissleder R
Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes.
ChemMedChem. 2014;9(7):1368-73 - PMID: 24596307 - PMCID: PMC4145401 - DOI: 10.1002/cmdc.201300506
Lartey FM, Ahn GO, Ali R, Rosenblum S, Miao Z, Arksey N, Shen B, Colomer MV, Rafat M, Liu H, Alejandre-Alcazar MA, Chen JW, Palmer T, Chin FT, Guzman R, Loo BW, Graves E
The Relationship Between Serial [(18) F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice.
Mol Imaging Biol. 2014;16(6):821-9 - PMID: 24865401 - PMCID: PMC4237703 - DOI: 10.1007/s11307-014-0745-0
Panizzi P, Stone JR, Nahrendorf M
Endocarditis and molecular imaging.
J Nucl Cardiol. 2014;21(3):486-95 - PMID: 24797384 - PMCID: PMC4106242 - DOI: 10.1007/s12350-014-9902-8
Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA
Computational pathology: an emerging definition.
Arch Pathol Lab Med. 2014;138(9):1133-8 - PMID: 25171694 - DOI: 10.5858/arpa.2014-0034-ED
Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Mode of Childbirth and Long-Term Outcomes in Women with Inflammatory Bowel Diseases.
Dig Dis Sci. 2014;60(2):471-7 - PMID: 25213079 - PMCID: PMC4304947 - DOI: 10.1007/s10620-014-3353-6
Wollack JW, Monson BJ, Dozier JK, Dalluge JJ, Poss K, Hilderbrand SA, Distefano MD
Site-Specific Labeling of Proteins and Peptides with Trans-cyclooctene Containing Handles Capable of Tetrazine Ligation.
Chem Biol Drug Des. 2014;84(2):140-7 - PMID: 24899362 - PMCID: PMC4107141 - DOI: 10.1111/cbdd.12303
Stone JR
Novel prognostic tissue markers in congestive heart failure.
Cardiovasc Pathol. 2014;24(2):65-70 - PMID: 25453729 - DOI: 10.1016/j.carpath.2014.07.010
Pauk M, Grgurevic L, Brkljacic J, Kufner V, Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt JL, Lin HY, Volarevic S, Vukicevic S
Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice.
Int Orthop. 2014;39(1):161-172 - PMID: 25300398 - DOI: 10.1007/s00264-014-2550-4
Zhao Y, Zhou P, Liu B, Bambakidis T, Mazitschek R, Alam HB, Li Y
Protective effect of suberoylanilide hydroxamic acid against lipopolysaccharide-induced liver damage in rodents.
J Surg Res. 2014;194(2):544-550 - PMID: 25479907 - PMCID: PMC4361238 - DOI: 10.1016/j.jss.2014.10.056
Zhao T, Li Y, Liu B, Halaweish I, Mazitschek R, Alam HB
Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model.
J Surg Res. 2014;190(2):647-54 - PMID: 24613069 - PMCID: PMC4267528 - DOI: 10.1016/j.jss.2014.01.056
Oklu R, Stone JR, Albadawi H, Watkins MT
Extracellular Traps in Lipid-Rich Lesions of Carotid Atherosclerotic Plaques: Implications for Lipoprotein Retention and Lesion Progression.
J Vasc Interv Radiol. 2014;25(4):631-4 - PMID: 24581730 - DOI: 10.1016/j.jvir.2013.12.567
Hedgire SS, Eberhardt SC, Borczuk R, McDermott S, Harisinghani MG
Interpretation and reporting multiparametric prostate MRI: a primer for residents and novices.
Abdom Imaging. 2014;39(5):1036-51 - PMID: 24566965 - DOI: 10.1007/s00261-014-0097-x
Iyer VR, Hedgire SS, Hoskote SS, Borczuk D, Harisinghani MG
Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up.
Abdom Imaging. 2014;40(6):1481-6 - PMID: 25516214 - DOI: 10.1007/s00261-014-0328-1
Winkler DA, Burden FR, Yan B, Weissleder R, Tassa C, Shaw S, Epa VC
Modelling and predicting the biological effects of nanomaterials.
SAR QSAR Environ Res. 2014;25(2):161-72 - PMID: 24625316 - DOI: 10.1080/1062936X.2013.874367
Higgins JM
Red Blood Cell Population Dynamics.
Clin Lab Med. 2014;35(1):43-57 - PMID: 25676371 - PMCID: PMC4717490 - DOI: 10.1016/j.cll.2014.10.002
Sheth RA, Bittencourt LK, Guimaraes AR
Diffusion-Weighted Imaging of the Male Pelvis.
Magn Reson Imaging Clin N Am. 2014;22(2):145-163 - PMID: 24792675 - DOI: 10.1016/j.mric.2014.01.003
Harisinghani MG
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Magn Reson Imaging Clin N Am. 2014;22(2):xi - PMID: 24792681 - DOI: 10.1016/j.mric.2014.02.001
Bell DL, Stapleton CJ, Terry AR, Stone JR, Ogilvy CS
Clinical presentation and treatment considerations of a ruptured posterior spinal artery pseudoaneurysm.
J Clin Neurosci. 2014;21(7):1273-6 - PMID: 24572933 - DOI: 10.1016/j.jocn.2014.01.002
Park D, Spencer JA, Lin CP, Scadden DT
Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair.
J Vis Exp. 2014;(87):ePub - PMID: 24894331 - PMCID: PMC4206246 - DOI: 10.3791/51289
Hedgire SS, Elmi A, Kambadakone AR, Yoon S, Blake M, Harisinghani MG
MDCT imaging of Alloderm biologic mesh spacers in the abdomen and pelvis - preliminary experience.
Clin Imaging. 2014;38(3):279-82 - PMID: 24556330 - DOI: 10.1016/j.clinimag.2013.12.020
Hedgire SS, Tabatabaei S, McDermott S, Feldman A, Dahl DM, Harisinghani MG
Diversion ahead: imaging appearance of urinary diversions and reservoirs.
Clin Imaging. 2014;38(4):418-427 - PMID: 24602415 - DOI: 10.1016/j.clinimag.2014.01.017
Swirski FK
Monocyte recruitment and macrophage proliferation in atherosclerosis.
Kardiol Pol. 2014;72(4):311-4 - PMID: 24526549 - DOI: 10.5603/KP.a2014.0021
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases.
Aliment Pharmacol Ther. 2014;39(10):1136-42 - PMID: 24641590 - PMCID: PMC4187206 - DOI: 10.1111/apt.12706
Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ
Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2.
Physiol Rep. 2014;2(12):ePub - PMID: 25472608 - PMCID: PMC4332208 - DOI: 10.14814/phy2.12226
Ausiello D, Shaw S
Quantitative human phenotyping: the next frontier in medicine.
Trans Am Clin Climatol Assoc. 2014;125:219-28 - PMID: 25125736 - PMCID: PMC4112685
Ali M, Pulli B, Chen JW
Molecular imaging of macrophage enzyme activity in cardiac inflammation.
Curr Cardiovasc Imaging Rep. 2014;7(4):9258 - PMID: 24729833 - PMCID: PMC3979571 - DOI: 10.1007/s12410-014-9258-0
Swirski FK
Inflammation and repair in the ischaemic myocardium.
Hamostaseologie. 2014;35(1):34-6 - PMID: 25375277 - DOI: 10.5482/HAMO-14-09-0045
Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy.
Nat Med. 2014;20(11):1301-9 - PMID: 25344738 - DOI: 10.1038/nm.3708
Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS, Reiner T
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.
ChemistryOpen. 2014;3(2):48-53 - PMID: 24808990 - PMCID: PMC4000166 - DOI: 10.1002/open.201402000
Core AB, Canali S, Babitt JL
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis.
Front Pharmacol. 2014;5:104 - PMID: 24860505 - PMCID: PMC4026703 - DOI: 10.3389/fphar.2014.00104
Alieva M, Ritsma L, Giedt RJ, Weissleder R, van Rheenen J
Imaging windows for long-term intravital imaging: general overview
Intravital. 2014;3:2: e29917
Wang CY, Meynard D, Lin HY
The role of TMPRSS6/matriptase-2 in iron regulation and anemia.
Front Pharmacol. 2014;5:114 - PMID: 24966834 - PMCID: PMC4053654 - DOI: 10.3389/fphar.2014.00114
Baron JM, Dighe AS, Arnaout R, Balis UJ, Black-Schaffer WS, Carter AB, Henricks WH, Higgins JM, Jackson BR, Kim J, Klepeis VE, Le LP, Louis DN, Mandelker D, Mermel CH, Michaelson JS, Nagarajan R, Platt ME, Quinn AM, Rao L, Shirts BH, Gilbertson JR
The 2013 symposium on pathology data integration and clinical decision support and the current state of field.
J Pathol Inform. 2014;5:2 - PMID: 24672737 - PMCID: PMC3952400 - DOI: 10.4103/2153-3539.126145
Mietto C, Pinciroli R, Piriyapatsom A, Thomas JG, Bry L, Delaney ML, Du Bois A, Truelove J, Ackman JB, Wojtkiewicz GR, Nahrendorf M, Kacmarek RM, Berra L
Tracheal Tube Obstruction in Mechanically Ventilated Patients Assessed by High-resolution Computed Tomography.
Anesthesiology. 2014;121(6):1226-1235 - PMID: 25254903 - DOI: 10.1097/ALN.0000000000000455
Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bø TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH, Straume O, Akslen LA, Watnick RS, Folkman J, Naumov GN
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors.
Mol Cancer Res. 2014;12(5):754-64 - PMID: 24574516 - PMCID: PMC4020951 - DOI: 10.1158/1541-7786.MCR-13-0532-T
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