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Pai SI, Wasserman I, Ji YD, Gilman M, Hung YP, Faquin WC, Mino-Kenudson M, Muniappan A

Pulmonary manifestations of chronic HPV infection in patients with recurrent respiratory papillomatosis
Lancet Respir Med. 2022;10(10):997-1008 - PMID: 35863360 - PMCID: PMC10634185 - DOI: 10.1016/S2213-2600(22)00008-X

Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy.
Nat Med. 2014;20(11):1301-9 - PMID: 25344738 - DOI: 10.1038/nm.3708

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
Nat Med. 2019;25(8):1264-1269 - PMID: 31263286 - PMCID: PMC6919319 - DOI: 10.1038/s41591-019-0493-4

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA

Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
Nat Med. 2019;25(10):1627 - PMID: 31501535 - DOI: 10.1038/s41591-019-0573-5

Chandrasekhar A, Padrós-Valls R, Pallarès-López R, Palanques-Tost E, Houstis N, Sundt TM, Lee HS, Sodini CG, Aguirre AD

Tissue perfusion pressure enables continuous hemodynamic evaluation and risk prediction in the intensive care unit.
Nat Med. 2023;29(8):1998-2006 - PMID: 37550417 - DOI: 10.1038/s41591-023-02474-6

Harisinghani MG, Barentsz J, Hahn PF, Deserno WM, Tabatabaei S, van de Kaa CH, de la Rosette J, Weissleder R

Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
N Engl J Med. 2003;348:2491-9 - PMID: 12815134 - DOI: 10.1056/NEJMoa022749

Merkel PA, McCarty D, Sharma A, Stone JR

Case records of the Massachusetts General Hospital. Case 31-2008. A 39-year-old man with chest pain, arthralgias, and a mediastinal mass.
N Engl J Med. 2008;359:1603-14 - PMID: 18843125 - DOI: 10.1056/NEJMcpc0805310

Brass SD, Durand ML, Stone JH, Chen JW, Stone JR

Case records of the Massachusetts General Hospital. Case 36-2008. A 59-year-old man with chronic daily headache.
N Engl J Med. 2008;359(21):2267-78 - PMID: 19020329 - DOI: 10.1056/NEJMcpc0805313

Kaufman DS, McDougal WS, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 30-2009. A 77-year-old man with recurrent transitional-cell carcinoma of the ureter.
N Engl J Med. 2009;361(13):1292-9 - PMID: 19776411 - DOI: 10.1056/NEJMcpc0900642

Stone JH, Papaliodis GN, Dunbar MR, Stone JR

Case 4-2010 -- a 53-year-old man with arthralgias, oral ulcers, vision loss, and vocal-cord paralysis.
N Engl J Med. 2010;362(6):537-46 - PMID: 20147720 - DOI: 10.1056/NEJMcpc0910090

Ng AK, Abramson JS, Digumarthy SR, Reingold JS, Stone JR

Case 24-2010.
N Engl J Med. 2010;363(7):664-675 - PMID: 20818858 - DOI: 10.1056/NEJMcpc1004087

Sabatine MS, Jaffer FA, Staats PN, Stone JR

Case records of the Massachusetts General Hospital. Case 28-2010. A 32-year-old woman, 3 weeks post partum, with substernal chest pain.
N Engl J Med. 2010;363(12):1164-73 - PMID: 20843252 - DOI: 10.1056/NEJMcpc1000966

Karchmer AW, MacGillivray TE, Healey TT, Stone JR

Case records of the Massachusetts General Hospital. Case 1-2011. A 35-year-old man with fever, bacteremia, and a mass in the left atrium.
N Engl J Med. 2011;364(2):158-66 - PMID: 21226582 - DOI: 10.1056/NEJMcpc1004362

Kaufman DS, Zietman AL, Dahl DM, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 5-2011. A 65-year-old man with hematuria after treatment for prostate cancer.
N Engl J Med. 2011;364(7):667-75 - PMID: 21323545 - DOI: 10.1056/NEJMcpc1005310

Kaufman DS, Zietman AL, McDougal WS, Dahl DM, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 9-2012. A 67-year-old man with a persistently elevated PSA level.
N Engl J Med. 2012;366(12):1143-50 - PMID: 22435374 - DOI: 10.1056/NEJMcpc1104320

Bazari H, Guimaraes AR, Kushner YB

Case records of the Massachusetts General Hospital. Case 20-2012. A 77-year-old man with leg edema, hematuria, and acute renal failure.
N Engl J Med. 2012;366(26):2503-15 - PMID: 22738101 - DOI: 10.1056/NEJMcpc1111577

Hunt DP, Becker AE, Guimaraes AR, Stemmer-Rachamimov A, Misdraji J

Case records of the Massachusetts General Hospital. Case 21-2012. A 27-year-old man with fatigue, weakness, weight loss, and decreased libido.
N Engl J Med. 2012;367(2):157-69 - PMID: 22784119 - DOI: 10.1056/NEJMcpc1110053

Zella GC, Gee MS, Badizadegan K

Case records of the Massachusetts General Hospital. Case 25-2012. A 15-year-old boy with abdominal pain, hematochezia, and anemia.
N Engl J Med. 2012;367(7):659-67 - PMID: 22894579 - DOI: 10.1056/NEJMcpc1111578

Stone JH, Patel VI, Oliveira GR, Stone JR

Case 38-2012.
N Engl J Med. 2012;367(24):2335-46 - PMID: 23234517 - DOI: 10.1056/NEJMcpc1209330

Steele DJ, Kasmar AG, Guimaraes AR, Dekker JP

Case records of the Massachusetts General Hospital. Case 3-2013. A 72-year-old woman with abdominal pain and distention after peritoneal dialysis.
N Engl J Med. 2013;368(4):375-85 - PMID: 23343067 - DOI: 10.1056/NEJMcpc1208142

Simmons LH, Guimaraes AR, Zukerberg LR

Case 6-2013.
N Engl J Med. 2013;368(8):757-65 - PMID: 23425169 - DOI: 10.1056/NEJMcpc1208149

Awad MM, Katayama R, McTigue M, Liu W, Deng YL, Brooun A, Friboulet L, Huang D, Falk MD, Timofeevski S, Wilner KD, Lockerman EL, Khan TM, Mahmood S, Gainor JF, Digumarthy SR, Stone JR, Mino-Kenudson M, Christensen JG, Iafrate AJ, Engelman JA, Shaw AT

Acquired Resistance to Crizotinib from a Mutation in CD74-ROS1.
N Engl J Med. 2013;368(25):2395-401 - PMID: 23724914 - PMCID: PMC3878821 - DOI: 10.1056/NEJMoa1215530

Olumi AF, Kaufman DS, Zietman A, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 25-2013. A 71-year-old man with hematuria and a mass in the bladder.
N Engl J Med. 2013;369(7):660-7 - PMID: 23944304 - DOI: 10.1056/NEJMcpc1209278

Baggett MV, Turbett SE, Schwartzenberg SS, Stone JR

Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure.
N Engl J Med. 2014;370(7):651-60 - PMID: 24521112 - DOI: 10.1056/NEJMcpc1310004

Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, Kinnunen L, Koistinen HA, Ladenvall C, Getz G, Correa A, Banahan BF, Gabriel S, Kathiresan S, Stringham HM, McCarthy MI, Boehnke M, Tuomilehto J, Haiman C, Groop L, Atzmon G, Wilson JG, Neuberg D, Altshuler D, Ebert BL

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.
N Engl J Med. 2014;371(26):2488-2498 - PMID: 25426837 - PMCID: PMC4306669 - DOI: 10.1056/NEJMoa1408617

Hogan C, Little BP, Carlson JCT, Freudenreich O, Ivkovic A, Baron JM

Case 5-2019: A 48-Year-Old Woman with Delusional Thinking and Paresthesia of the Right Hand.
N Engl J Med. 2019;380(7):665-674 - PMID: 30763197 - DOI: 10.1056/NEJMcpc1807495

Carlson JCT, Hogan C, Ivkovic A

Case 5-2019: A Woman with Delusional Thinking and Paresthesia of the Right Hand. Reply.
N Engl J Med. 2019;380(21):2082 - PMID: 31116941 - DOI: 10.1056/NEJMc1903635

Finn KM, Sutphin PD, Carlson JCT, Raskin KA, Van Cott EM

Case 17-2021: An 82-Year-Old Woman with Pain, Swelling, and Ecchymosis of the Left Arm.
N Engl J Med. 2021;384(23):2242-2250 - PMID: 34107184 - DOI: 10.1056/NEJMcpc2100281

Carlson JCT, Sertic MM, Chen MY

Case 6-2024: A 21-Year-Old Man with Fatigue and Night Sweats.
N Engl J Med. 2024;390(8):747-756 - PMID: 38381678 - DOI: 10.1056/NEJMcpc2309498

Weissleder R, Lee H

Automated molecular-image cytometry and analysis in modern oncology
Nature Review Materials. 2020;:ePub - DOI: 10.1038/s41578-020-0180-6

Weissleder R

Scaling down imaging: molecular mapping of cancer in mice
Nat Rev Cancer. 2002;2:1-8 - PMID: 11902581 - DOI: 10.1038/nrc701

Engblom C, Pfirschke C, Pittet MJ

The role of myeloid cells in cancer therapies.
Nat Rev Cancer. 2016;16(7):447-62 - PMID: 27339708 - DOI: 10.1038/nrc.2016.54

Miller MA, Weissleder R

Imaging of anticancer drug action in single cells
Nat Rev Cancer. 2017;17(7):399–414 - PMID: 28642603 - PMCID: PMC7552440 - DOI: 10.1038/nrc.2017.41

Naxerova K

Evolutionary paths towards metastasis.
Nat Rev Cancer. 2025;25(7):545-560 - PMID: 40263543 - DOI: 10.1038/s41568-025-00814-x

Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T

Restoration of p53 function leads to tumour regression in vivo.
Nature. 2007;445:661-5 - PMID: 17251932 - DOI: 10.1038/nature05541

Weissleder R, Pittet MJ

Imaging in the era of molecular oncology
Nature. 2008;452:580-589 - PMID: 18385732 - PMCID: PMC2708079 - DOI: 10.1038/nature06917

Celso CL, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Cote D, Rowe DW, Lin CP, Scadden DT.

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434

Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH

HDAC2 negatively regulates memory formation and synaptic plasticity.
Nature. 2009;459(7243):55-60 - PMID: 19424149 - PMCID: PMC3498958 - DOI: 10.1038/nature07925

Mikkelsen T, Ku M, Jaffe D, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim T, Koche R, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander E, Bernstein B

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
Nature. 2007;448(7153):553-60 - PMID: 17603471 - PMCID: PMC2921165 - DOI: 10.1038/nature06008

Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP

In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.
Nature. 2005;435:969-73 - PMID: 15959517 - PMCID: PMC2570168 - DOI: 10.1038/nature03703

Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT

Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature. 2009;459(7243):103-7 - PMID: 19322176 - PMCID: PMC2761017 - DOI: 10.1038/nature07859

Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, C

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434

Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, Rogers J, Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B, Cook L, Davenport R, Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B, Schaffner S, Van Etten WJ, Reich D, Higgins J, Daly MJ, Blumenstiel B, Baldwin J, Stange-Thomann N, Zody MC, Linton L, Lander ES, Altshuler D,

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms.
Nature. 2001;409(6822):928-33 - PMID: 11237013 - DOI: 10.1038/35057149

Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, Schaffner SF, Gabriel SB, Platko JV, Patterson NJ, McDonald GJ, Ackerman HC, Campbell SJ, Altshuler D, Cooper R, Kwiatkowski D, Ward R, Lander ES

Detecting recent positive selection in the human genome from haplotype structure.
Nature. 2002;419(6909):832-7 - PMID: 12397357 - DOI: 10.1038/nature01140

Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ

Epigenetic memory in induced pluripotent stem cells.
Nature. 2010;467(7313):285-90 - PMID: 20644535 - PMCID: PMC3150836 - DOI: 10.1038/nature09342

Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR

Initial genome sequencing and analysis of multiple myeloma.
Nature. 2011;471(7339):467-72 - PMID: 21430775 - PMCID: PMC3560292 - DOI: 10.1038/nature09837

Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE

Mapping and analysis of chromatin state dynamics in nine human cell types.
Nature. 2011;473(7345):43-9 - PMID: 21441907 - PMCID: PMC3088773 - DOI: 10.1038/nature09906

Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Celso CL, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP

In vivo imaging of T(reg) cells providing immune privilege to the haematopoietic stem-cell niche.
Nature. 2011;474(7350):216-9 - PMID: 21654805 - PMCID: PMC3725645 - DOI: 10.1038/nature10160

Dutta P*, Courties G*, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AN, Niessen HWM, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M

Myocardial infarction accelerates atherosclerosis
Nature. 2012;487(7407):325-9 - PMID: 22763456 - PMCID: PMC3401326 - DOI: 10.1038/nature11260

Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL

Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.
Nature. 2012;489(7414):155-9 - PMID: 22820254 - PMCID: PMC3991463 - DOI: 10.1038/nature11303
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