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Shao H, Im H, Castro CM, Breakefield X, Weissleder R, Lee H
New Technologies for Analysis of Extracellular Vesicles.
Chem Rev. 2018;:ePub - PMID: 29384376 - DOI: 10.1021/acs.chemrev.7b00534
Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R
Fluorescence anisotropy imaging in drug discovery.
Adv Drug Deliv Rev. 2018;:ePub - PMID: 29410158 - DOI: 10.1016/j.addr.2018.01.019
Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M
Cardiac macrophages promote diastolic dysfunction.
J Exp Med. 2018;215(2):423-440 - PMID: 29339450 - PMCID: PMC5789416 - DOI: 10.1084/jem.20171274 - Cover
Honold L, Nahrendorf M
Resident and Monocyte-Derived Macrophages in Cardiovascular Disease.
Circ Res. 2018;122(1):113-127 - PMID: 29301844 - PMCID: PMC5777215 - DOI: 10.1161/CIRCRESAHA.117.311071
Carlson J, Mikula H, Weissleder R
Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage.
J Am Chem Soc. 2018;:ePub - PMID: 29384666 - DOI: 10.1021/jacs.7b11217
Chen L, Lee JW, Chou CL, Nair AV, Battistone MA, Păunescu TG, Merkulova M, Breton S, Verlander JW, Wall SM, Brown D, Burg MB, Knepper MA
Reply to Edemir: Physiological regulation and single-cell RNA sequencing.
Proc Natl Acad Sci U S A. 2018;115(3):E351-E352 - PMID: 29311339 - PMCID: PMC5777009 - DOI: 10.1073/pnas.1720333115
Nahrendorf M, Vandoorne K
Albumin-Binding MR Probe Detects High-Risk Coronary Plaques in Patients.
JACC Cardiovasc Imaging. 2018;:ePub - PMID: 29361477 - DOI: 10.1016/j.jcmg.2017.11.026
Ryu WS, Bae EK, Park SH, Jeong SW, Schellingerhout D, Nahrendorf M, Kim DE
Increased Left Ventricular Filling Pressure and Arterial Occlusion in Stroke Related to Atrial Fibrillation.
J Stroke Cerebrovasc Dis. 2018;:ePub - PMID: 29310958 - DOI: 10.1016/j.jstrokecerebrovasdis.2017.12.009
Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, Shin LM, Fayad ZA, Pitman RK
Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study.
Lancet. 2017;389(10071):834-845 - PMID: 28088338 - DOI: 10.1016/S0140-6736(16)31714-7
Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Nature. 2017;547(7663):355-359 - PMID: 28678782 - DOI: 10.1038/nature23000
Miller MA, Weissleder R
Imaging of anticancer drug action in single cells
Nat Rev Cancer. 2017;17(7):399–414 - PMID: 28642603 - DOI: 10.1038/nrc.2017.41
Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M
Cellular uptake of nanoparticles: journey inside the cell.
Chem Soc Rev. 2017;46(14):4218-4244 - PMID: 28585944 - PMCID: PMC5593313 - DOI: 10.1039/c6cs00636a
Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG
Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.
Nat Biotechnol. 2017;36(2):179-189 - PMID: 29251726 - PMCID: PMC5800952 - DOI: 10.1038/nbt.4048
Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL
Cohesin Loss Eliminates All Loop Domains.
Cell. 2017;171(2):305-320.e24 - PMID: 28985562 - DOI: 10.1016/j.cell.2017.09.026
Puram SV, Tirosh I, Parikh AS, Patel AP, Yizhak K, Gillespie S, Rodman C, Luo CL, Mroz EA, Emerick KS, Deschler DG, Varvares MA, Mylvaganam R, Rozenblatt-Rosen O, Rocco JW, Faquin WC, Lin DT, Regev A, Bernstein BE
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.
Cell. 2017;171(7):1611-1624.e24 - PMID: 29198524 - DOI: 10.1016/j.cell.2017.10.044
Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M
Macrophages Facilitate Electrical Conduction in the Heart
Cell. 2017;169:510-522 - PMID: 28431249 - PMCID: PMC5474950 - DOI: 10.1016/j.cell.2017.03.050
Flavahan WA, Gaskell E, Bernstein BE
Epigenetic plasticity and the hallmarks of cancer.
Science. 2017;357(6348):ePub - PMID: 28729483 - DOI: 10.1126/science.aal2380
Engblom C*, Pfirschke C*, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils
Science. 2017;358:eaal5081 - PMID: 29191879 - DOI: 10.1126/science.aal5081
Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, Mount C, Onozato ML, Nahed BV, Wakimoto H, Curry WT, Iafrate AJ, Rivera MN, Frosch MP, Golub TR, Brastianos PK, Getz G, Patel AP, Monje M, Cahill DP, Rozenblatt-Rosen O, Louis DN, Bernstein BE, Regev A, Suvà ML
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.
Science. 2017;355(6332):ePub - PMID: 28360267 - PMCID: PMC5519096 - DOI: 10.1126/science.aai8478
Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK
Origins of lymphatic and distant metastases in human colorectal cancer.
Science. 2017;357(6346):55-60 - PMID: 28684519 - PMCID: PMC5536201 - DOI: 10.1126/science.aai8515
King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng Jr RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R
IRF3 and type I interferons fuel a fatal response to myocardial infarction
Nature Med. 2017;23(12):1481-1487 - PMID: 29106401 - DOI: 10.1038/nm.4428
Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkins M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms.
Cancer Cell. 2017;33(1):29-43.e7 - PMID: 29249691 - PMCID: PMC5760343 - DOI: 10.1016/j.ccell.2017.11.009
Pfirschke C, Siwicki M, Liao HW, Pittet MJ
Tumor Microenvironment: No Effector T Cells without Dendritic Cells.
Cancer Cell. 2017;31(5):614-615 - PMID: 28486102 - DOI: 10.1016/j.ccell.2017.04.007
Frenk NE, Spring L, Muzikansky A, Vadvala HV Gurski JM Jr, Henderson LE, Mino-Kenudson M, Ly A, Bardia A, Finkelstein D, Engelman J, Mueller PR, Juric D, Weissleder R
High-Content Biopsies Facilitate Molecular Analyses and Do Not Increase Complication Rates in Patients With Advanced Solid Tumors
JCO Precis Oncol. 2017;1:1-9
Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R
Evolution of macromolecular complexity in drug delivery systems
Nat Rev Chem. 2017;1:0063 - DOI: doi:10.1038/s41570-017-0063
Miller MA
Counting on carbon quantum dots to clear infection
Sci Transl Med. 2017;9(399):eaao0969
Miller MA
Driver mutations take the wheel in invasive yet nonmalignant disease.
Sci Transl Med. 2017;9(393):ePub - PMID: 28592567 - DOI: 10.1126/scitranslmed.aan8194
Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts
Sci Transl Med. 2017;9(392):eaal0225 - PMID: 28566423 - DOI: 10.1126/scitranslmed.aal0225
Miller MA
Nanoparticles improve economic mileage for CARs.
Sci Transl Med. 2017;9(387):ePub - PMID: 28446684 - DOI: 10.1126/scitranslmed.aan2784
Yang KS*, Im H*, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R
Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy
Sci Transl Med. 2017;9(391):eaal3226 - PMID: 28539469 - DOI: 10.1126/scitranslmed.aal3226
Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, Wong CSF, Kloepper J, Das R, Tam A, Tanboon J, Duda DG, Miller CR, Siegel MB, Anders CK, Sanders M, Estrada MV, Schlegel R, Arteaga CL, Brachtel E, Huang A, Fukumura D, Engelman JA, Jain RK
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation.
Sci Transl Med. 2017;9(391):ePub - PMID: 28539475 - DOI: 10.1126/scitranslmed.aal4682
King KR
Squeeze-E squeeze-E.
Sci Transl Med. 2017;9(382):ePub - PMID: 28330860 - DOI: 10.1126/scitranslmed.aan0766
Arlauckas SP*, Garris CS*, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ
In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy
Sci Transl Med. 2017;9(389):eaal3604 - PMID: 28490665 - PMCID: PMC5734617 - DOI: 10.1126/scitranslmed.aal3604 - Cover
Miller MA
Nanotransfection brings progress that’s more than skin-deep
Sci Transl Med. 2017;9(405):eaao4216
King KR
Stunning neutrophils changes the forecast: No more showers.
Sci Transl Med. 2017;9(388):ePub - PMID: 28469035 - DOI: 10.1126/scitranslmed.aan3775
Castro CM
Good to the last "emulsified" drop.
Sci Transl Med. 2017;9(373):ePub - PMID: 28100835 - DOI: 10.1126/scitranslmed.aal4993
Miller MA
Less is more for anticancer therapy combinations
Sci Transl Med. 2017;9 (411):aap8166 - DOI: 10.1126/scitranslmed.aap8166
Miller MA
It’s what’s inside that counts for nanoparticle vaccines
Sci Transl Med. 2017;9(417):eaar2438 - DOI: 10.1126/scitranslmed.aar2438
Miller MA
Richer data with personalized GEMs.
Sci Transl Med. 2017;9(381):ePub - PMID: 28298424 - DOI: 10.1126/scitranslmed.aam9865
Miller MA, Weissleder R
Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior
Adv Drug Deliv Rev. 2017;113:61-86 - PMID: 27266447 - PMCID: PMC5136524 - DOI: 10.1016/j.addr.2016.05.023
Alaarg A, Pérez-Medina C, Metselaar JM, Nahrendorf M, Fayad ZA, Storm G, Mulder WJM
Applying nanomedicine in maladaptive inflammation and angiogenesis.
Adv Drug Deliv Rev. 2017;119:143-158 - PMID: 28506745 - PMCID: PMC5682240 - DOI: 10.1016/j.addr.2017.05.009
Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard B, Neidhart M, Stroes ESG, Catapano AL, Bekkering S
Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.
Eur Heart J. 2017;:ePub - PMID: 29069365 - DOI: 10.1093/eurheartj/ehx581
Frodermann V, Nahrendorf M
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2017;38(3):198-200 - PMID: 28158564 - DOI: 10.1093/eurheartj/ehw085
Hoyer FF, Nahrendorf M
Neutrophil contributions to ischaemic heart disease.
Eur Heart J. 2017;38(7):465-472 - PMID: 28363210 - DOI: 10.1093/eurheartj/ehx017
Nahrendorf M, Swirski FK
Cholesterol, CCR2, and monocyte phenotypes in atherosclerosis.
Eur Heart J. 2017;38(20):1594-1596 - PMID: 28329093 - DOI: 10.1093/eurheartj/ehx098
Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.
J Exp Med. 2017;214(11):3293-3310 - PMID: 28978634 - PMCID: PMC5679174 - DOI: 10.1084/jem.20170689
Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN
Unraveling Vascular Inflammation: From Immunology to Imaging.
J Am Coll Cardiol. 2017;70(11):1403-1412 - PMID: 28882238 - PMCID: PMC5658004 - DOI: 10.1016/j.jacc.2017.07.750
Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK
Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.
J Am Coll Cardiol. 2017;69(20):2502-2513 - PMID: 28521888 - DOI: 10.1016/j.jacc.2017.03.556
Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ
mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.
J Clin Invest. 2017;127(6):2433-2437 - PMID: 28481220 - PMCID: PMC5451245 - DOI: 10.1172/JCI92030
Seo KJ, Qiang Y, Bilgin I, Kar S, Vinegoni C, Weissleder R, Fang H
Transparent Electrophysiology Microelectrodes and Interconnects from Metal Nanomesh.
ACS Nano. 2017;11(4):4365-4372 - PMID: 28391679 - DOI: 10.1021/acsnano.7b01995
Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca A, Breakefield XO, Lee H, Weissleder R
Multiplexed Profiling of Single Extracellular Vesicles.
ACS Nano. 2017;12(1):494-503 - PMID: 29286635 - DOI: 10.1021/acsnano.7b07060
Park J, Lin HY, Assaker JP, Jeong S, Huang CH, Kurdi A, Lee K, Fraser K, Min C, Eskandari S, Routray S, Tannous BA, Abdi R, Riella L, Chandraker A, Castro CM, Weissleder R, Lee H, Azzi JR
Integrated Kidney Exosome Analysis (iKEA) For The Detection Of Kidney Transplant Rejection.
ACS Nano. 2017;11(11):11041-11046 - PMID: 29053921 - DOI: 10.1021/acsnano.7b05083
Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H
Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection.
ACS Nano. 2017;11(10):10062-10069 - PMID: 28792732 - DOI: 10.1021/acsnano.7b04318
Park K, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H
Nano-Magnetic System For Rapid Diagnosis Of Acute Infection.
ACS Nano. 2017;11(11):11425-11432 - PMID: 29121461 - DOI: 10.1021/acsnano.7b06074
Park CO, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JH, Jung Y, Watanabe R, Fuhlbrigge RC, Carbone FR, Gebhardt T, Clark RA, Lin CP, Kupper TS
Staged development of long lived TCRαβ Th17 resident memory T cell population to Candida albicans after skin infection.
J Allergy Clin Immunol. 2017;:ePub - PMID: 29128674 - DOI: 10.1016/j.jaci.2017.09.042
Franck G, Mawson T, Sausen G, Salinas M, Masson GS, Cole A, Beltrami-Moreira M, Chatzizisis Y, Quillard T, Tesmenitsky Y, Shvartz E, Sukhova GK, Swirski FK, Nahrendorf M, Aikawa E, Croce KJ, Libby P
Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion.
Circ Res. 2017;121(1):31-42 - PMID: 28428204 - PMCID: PMC5488735 - DOI: 10.1161/CIRCRESAHA.117.310694
Swirski FK, Nahrendorf M
Inflammation: Old, caffeinated, and healthy.
Nat Rev Cardiol. 2017;14(4):194-196 - PMID: 28250451 - DOI: 10.1038/nrcardio.2017.22
Swirski FK
Inflammation and CVD in 2017: From clonal haematopoiesis to the CANTOS trial.
Nat Rev Cardiol. 2017;15(2):79-80 - PMID: 29263444 - DOI: 10.1038/nrcardio.2017.208
Harada T, Ohguchi H, Grondin Y, Kikuchi S, Sagawa M, Tai YT, Mazitschek R, Hideshima T, Anderson KC
HDAC3 regulates DNMT1 expression in multiple myeloma: Therapeutic implications.
Leukemia. 2017;31(12):2670-2677 - PMID: 28490812 - PMCID: PMC5681897 - DOI: 10.1038/leu.2017.144
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL
PD-L1 is an activation-independent marker of brown adipocytes.
Nat Commun. 2017;8(1):647 - PMID: 28935898 - PMCID: PMC5608754 - DOI: 10.1038/s41467-017-00799-8
Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.
Nat Commun. 2017;8:15142 - PMID: 28485378 - PMCID: PMC5436068 - DOI: 10.1038/ncomms15142
Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.
Nat Commun. 2017;8:14293 - PMID: 28176769 - PMCID: PMC5309815 - DOI: 10.1038/ncomms14293
Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R
Nano-palladium is a cellular catalyst for in vivo chemistry
Nat Commun. 2017;8:15906 - PMID: 28699627 - PMCID: PMC5510178 - DOI: 10.1038/ncomms15906
Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.
Nat Commun. 2017;8:14064 - PMID: 28091604 - PMCID: PMC5241815 - DOI: 10.1038/ncomms14064
Kitano K, Schwartz DM, Zhou H, Gilpin SE, Wojtkiewicz GR, Ren X, Sommer CA, Capilla AV, Mathisen DJ, Goldstein AM, Mostoslavsky G, Ott HC
Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts.
Nat Commun. 2017;8(1):765 - PMID: 29018244 - PMCID: PMC5635127 - DOI: 10.1038/s41467-017-00779-y
Grossman SR, Zhang X, Wang L, Engreitz J, Melnikov A, Rogov P, Tewhey R, Isakova A, Deplancke B, Bernstein BE, Mikkelsen TS, Lander ES
Systematic dissection of genomic features determining transcription factor binding and enhancer function.
Proc Natl Acad Sci U S A. 2017;114(7):E1291-E1300 - PMID: 28137873 - PMCID: PMC5321001 - DOI: 10.1073/pnas.1621150114
Chaudhury A, Noiret L, Higgins JM
White blood cell population dynamics for risk stratification of acute coronary syndrome.
Proc Natl Acad Sci U S A. 2017;114(46):12344-12349 - PMID: 29087321 - PMCID: PMC5699055 - DOI: 10.1073/pnas.1709228114
Chen L, Lee JW, Chou CL, Nair AV, Battistone MA, Păunescu TG, Merkulova M, Breton S, Verlander JW, Wall SM, Brown D, Burg MB, Knepper MA
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq.
Proc Natl Acad Sci U S A. 2017;114(46):E9989-E9998 - PMID: 29089413 - PMCID: PMC5699061 - DOI: 10.1073/pnas.1710964114
He Q, Bouley R, Liu Z, Wein MN, Zhu Y, Spatz JM, Wang CY, Divieti Pajevic P, Plagge A, Babitt JL, Bastepe M
Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo.
Proc Natl Acad Sci U S A. 2017;114(45):E9559-E9568 - PMID: 29078380 - PMCID: PMC5692581 - DOI: 10.1073/pnas.1712670114
Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I
Stress granule-associated protein G3BP2 regulates breast tumor initiation.
Proc Natl Acad Sci U S A. 2017;114(5):1033-1038 - PMID: 28096337 - PMCID: PMC5293063 - DOI: 10.1073/pnas.1525387114
Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C
Imaging the emergence and natural progression of spontaneous autoimmune diabetes.
Proc Natl Acad Sci U S A. 2017;114(37):E7776-E7785 - PMID: 28839093 - PMCID: PMC5604023 - DOI: 10.1073/pnas.1707381114
Shah N, Wang P, Wongvipat J, Karthaus WR, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein BE, Long HW, Freedman ML, Arora VK, Zheng D, Sawyers CL
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer.
eLife. 2017;6:ePub - PMID: 28891793 - PMCID: PMC5593504 - DOI: 10.7554/eLife.27861
Wang CY, Core AB, Canali S, Zumbrennen-Bullough KB, Ozer S, Umans L, Zwijsen A, Babitt JL
Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice.
Blood. 2017;130(1):73-83 - PMID: 28438754 - PMCID: PMC5501149 - DOI: 10.1182/blood-2016-12-759423
Nigwekar SU, Weiser JM, Kalim S, Xu D, Wibecan JL, Dougherty SM, Mercier-Lafond L, Corapi KM, Eneanya ND, Holbrook EH, Brown D, Thadhani RI, Păunescu TG
Characterization and Correction of Olfactory Deficits in Kidney Disease.
J Am Soc Nephrol. 2017;28(11):3395-3403 - PMID: 28775001 - PMCID: PMC5661283 - DOI: 10.1681/ASN.2016121308
Battistone MA, Nair AV, Barton CR, Liberman RN, Peralta MA, Capen DE, Brown D, Breton S
Extracellular Adenosine Stimulates Vacuolar ATPase-Dependent Proton Secretion in Medullary Intercalated Cells.
J Am Soc Nephrol. 2017;29(2):545-556 - PMID: 29222395 - PMCID: PMC5791049 - DOI: 10.1681/ASN.2017060643
Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R
Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging.
Theranostics. 2017;7(5):1257-1265 - PMID: 28435463 - PMCID: PMC5399591 - DOI: 10.7150/thno.18238
Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R
Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.
Nat Protoc. 2017;12(7):1472-1497 - PMID: 28686582 - DOI: 10.1038/nprot.2017.043
Bourgeois S, Bounoure L, Mouro-Chanteloup I, Colin Y, Brown D, Wagner CA
The ammonia transporter RhCG modulates urinary acidification by interacting with the vacuolar proton-ATPases in renal intercalated cells.
Kidney Int. 2017;93(2):390-402 - PMID: 29054531 - DOI: 10.1016/j.kint.2017.07.027
Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman E, Garcia AR, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle B, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov MG, Sequist LV, Bernstein BE, Ebi H, Engelman JA, Faber AC
Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM.
Clin Cancer Res. 2017;24(1):197-208 - PMID: 29051323 - DOI: 10.1158/1078-0432.CCR-17-1577
Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Crain JA, Jacobson A, Michelakos T, Dias-Santos D, Zanconato A, Hong TS, Clark JW, Murphy JE, Ryan DP, Deshpande V, Lillemoe KD, Fernandez-Del Castillo C, Downes M, Evans RM, Michaelson J, Ferrone CR, Boucher Y, Jain RK
Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma.
Clin Cancer Res. 2017;23(19):5959-5969 - PMID: 28600474 - DOI: 10.1158/1078-0432.CCR-17-0256
Meyer IS, Jungmann A, Dieterich C, Zhang M, Lasitschka F, Werkmeister S, Haas J, Müller OJ, Boutros M, Nahrendorf M, Katus HA, Hardt SE, Leuschner F
The cardiac microenvironment uses non-canonical WNT signaling to activate monocytes after myocardial infarction.
EMBO Mol Med. 2017;9(9):1279-1293 - PMID: 28774883 - PMCID: PMC5582413 - DOI: 10.15252/emmm.201707565
Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE
Preclinical investigation of gene-mediated cytotoxic immunotherapy and checkpoint blockade in glioblastoma.
Neuro Oncol. 2017;20(2):225-235 - PMID: 29016938 - PMCID: PMC5777502 - DOI: 10.1093/neuonc/nox139
Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS
A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.
Cell Rep. 2017;21(3):784-797 - PMID: 29045844 - PMCID: PMC5687286 - DOI: 10.1016/j.celrep.2017.09.066
Wilk K, Yeh SA, Mortensen LJ, Ghaffarigarakani S, Lombardo CM, Bassir SH, Aldawood ZA, Lin CP, Intini G
Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration.
Stem Cell Reports. 2017;8(4):933-946 - PMID: 28366454 - PMCID: PMC5390237 - DOI: 10.1016/j.stemcr.2017.03.002
Godlewski J, Ferrer-Luna R, Rooj AK, Mineo M, Ricklefs F, Takeda YS, Nowicki MO, Salińska E, Nakano I, Lee H, Weissleder R, Beroukhim R, Chiocca EA, Bronisz A
MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer.
Stem Cell Reports. 2017;8(6):1497-1505 - PMID: 28528698 - PMCID: PMC5470095 - DOI: 10.1016/j.stemcr.2017.04.024
Brown D, Sands JM, Reckelhoff JF
APS: The Times They Are A-Changin'.
Physiology (Bethesda). 2017;32(6):400-401 - PMID: 28978629 - DOI: 10.1152/physiol.00025.2017
Park J*, Im H*, Hong S, Castro CM, Weissleder R, Hakho Lee H
Analyses of Intravesicular Exosomal Proteins Using a Nano-Plasmonic System
ACS Photonics. 2017;:ePub - DOI: 10.1021/acsphotonics.7b00992
She A, Kurtser I, Reis SA, Hennig K, Lai J, Lang A, Zhao WN, Mazitschek R, Dickerson BC, Herz J, Haggarty SJ
Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.
Cell Chem Biol. 2017;24(7):892-906.e5 - PMID: 28712747 - PMCID: PMC5695697 - DOI: 10.1016/j.chembiol.2017.06.010
Hideshima T, Mazitschek R, Qi J, Mimura N, Tseng JC, Kung AL, Bradner JE, Anderson KC
HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.
Oncotarget. 2017;:ePub - PMID: 28708596
Hideshima T, Mazitschek R, Qi J, Mimura N, Tseng JC, Kung AL, Bradner JE, Anderson KC
HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.
Oncotarget. 2017;8(46):80109-80123 - PMID: 29113288 - PMCID: PMC5655183 - DOI: 10.18632/oncotarget.19019
Hwang I, Oh H, Santo E, Kim DY, Chen JW, Bronson RT, Locasale JW, Na Y, Lee J, Reed S, Toth M, Yu WH, Muller FL, Paik J
FOXO protects against age-progressive axonal degeneration.
Aging Cell. 2017;:ePub - PMID: 29178390 - PMCID: PMC5771393 - DOI: 10.1111/acel.12701
Pulli B, Wojtkiewicz G, Iwamoto Y, Ali M, Zeller MW, Bure L, Wang C, Choi Y, Masia R, Guimaraes AR, Corey KE, Chen JW
Molecular MR Imaging of Myeloperoxidase Distinguishes Steatosis from Steatohepatitis in Nonalcoholic Fatty Liver Disease.
Radiology. 2017;:160588 - PMID: 28358240 - PMCID: PMC5548451 - DOI: 10.1148/radiol.2017160588
Fenn AM, Swirski FK
Monocytosis, Hypercholesterolemia, and the Kinase That Binds Them.
Arterioscler Thromb Vasc Biol. 2017;37(2):173-175 - PMID: 28122772 - DOI: 10.1161/ATVBAHA.116.308768
Hong S, Park KS, Weissleder R, Castro CM, Lee H
Facile silicification of plastic surface for bioassays.
Chem Commun. 2017;53(13):2134-2137 - PMID: 28134385 - PMCID: PMC5327824 - DOI: 10.1039/c6cc09359k
Miller MA, Kim E, Cuccarese MF, Plotkin AL, Prytyskach M, Kohler RH, Pittet MJ, Weissleder R
Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease
Chem Commun. 2017;54(1):42-45 - PMID: 29185561 - PMCID: PMC5736449 - DOI: 10.1039/c7cc07581b
Kim DE, Kim JY, Schellingerhout D, Ryu JH, Lee SK, Jeon S, Lee JS, Kim J, Jang HJ, Park JE, Kim EJ, Kwon IC, Ahn CH, Nahrendorf M, Kim K
Quantitative Imaging of Cerebral Thromboemboli In Vivo: The Effects of Tissue-Type Plasminogen Activator.
Stroke. 2017;48(5):1376-1385 - PMID: 28432262 - DOI: 10.1161/STROKEAHA.117.016511
Tokarz D, Martins JS, Petit ET, Lin CP, Demay MB, Liu ES
Hormonal regulation of osteocyte perilacunar and canalicular remodeling in the Hyp mouse model of XLH.
J Bone Miner Res. 2017;:ePub - PMID: 29083055 - DOI: 10.1002/jbmr.3327
Im H, Lee K, Weissleder R, Lee H, Castro CM
Novel nanosensing technologies for exosome detection and profiling.
Lab Chip. 2017;17(17):2892-2898 - PMID: 28745363 - PMCID: PMC5572557 - DOI: 10.1039/c7lc00247e
Min C, Park J, Mun JK, Lim Y, Min J, Lim JW, Kang DM, Ahn HK, Shin TH, Cheon J, Lee HS, Weissleder R, Castro CM, Lee H
Integrated microHall magnetometer to measure the magnetic properties of nanoparticles.
Lab Chip. 2017;17(23):4000-4007 - PMID: 29067383 - PMCID: PMC5698130 - DOI: 10.1039/c7lc00934h
Verweij SL, Duivenvoorden R, Stiekema LCA, Nurmohamed NS, van der Valk FM, Versloot M, Verberne HJ, Stroes ESG, Nahrendorf M, Bekkering S, Bernelot Moens SJ
CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease.
Cardiovasc Res. 2017;:ePub - PMID: 29186373 - DOI: 10.1093/cvr/cvx224
Li W, Jin WW, Tsuji K, Chen Y, Nomura N, Su L, Yui N, Arthur J, Cotecchia S, Păunescu TG, Brown D, Lu HAJ
Direct interaction of ezrin and AQP2 and its role in AQP2 trafficking.
J Cell Sci. 2017;130(17):2914-2925 - PMID: 28754689 - PMCID: PMC5612225 - DOI: 10.1242/jcs.204842
Stein-Merlob AF, Hara T, McCarthy JR, Mauskapf A, Hamilton JA, Ntziachristos V, Libby P, Jaffer FA
Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging.
Circ Cardiovasc Imaging. 2017;10(5):ePub - PMID: 28487316 - PMCID: PMC5509162 - DOI: 10.1161/CIRCIMAGING.116.005813
Vandoorne K, Nahrendorf M
Multiparametric Imaging of Organ System Interfaces.
Circ Cardiovasc Imaging. 2017;10(4):ePub - PMID: 28360260 - PMCID: PMC5419074 - DOI: 10.1161/CIRCIMAGING.116.005613
Vunnam S, Mazitschek R, Kariem NM, Reddy A, Rabeh W, Li L, O'Connor MJ, Al-Tel TH
Modular Bi-Directional One-Pot Strategies for the Diastereoselective Synthesis of Structurally Diverse Collections of Constrained β-Carboline-Benzoxazepines.
Chemistry. 2017;23(57):14182-14192 - PMID: 28770556 - DOI: 10.1002/chem.201702495
Global Cardiovascular Magnetic Resonance Registry (GCMR) Investigators, Kwong RY, Petersen SE, Schulz-Menger J, Arai AE, Bingham SE, Chen Y, Choi YL, Cury RC, Ferreira VM, Flamm SD, Steel K, Bandettini WP, Martin ET, Nallamshetty L, Neubauer S, Raman SV, Schelbert EB, Valeti US, Cao JJ, Reichek N, Young AA, Fexon L, Pivovarov M, Ferrari VA, Simonetti OP
The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments.
J Cardiovasc Magn Reson. 2017;19(1):23 - PMID: 28187739 - PMCID: PMC5303267 - DOI: 10.1186/s12968-016-0321-7
Nairz M, Haschka D, Dichtl S, Sonnweber T, Schroll A, Aßhoff M, Mindur JE, Moser PL, Wolf D, Swirski FK, Theurl I, Cerami A, Brines M, Weiss G
Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis.
Sci Rep. 2017;7(1):13012 - PMID: 29026145 - PMCID: PMC5638901 - DOI: 10.1038/s41598-017-13046-3
Beam AL, Kartoun U, Pai JK, Chatterjee AK, Fitzgerald TP, Shaw SY, Kohane IS
Predictive Modeling of Physician-Patient Dynamics That Influence Sleep Medication Prescriptions and Clinical Decision-Making.
Sci Rep. 2017;7:42282 - PMID: 28181568 - PMCID: PMC5299453 - DOI: 10.1038/srep42282
Turcotte R, Alt C, Runnels JM, Ito K, Wu JW, Zaher W, Mortensen LJ, Silberstein L, Côté DC, Kung AL, Ito K, Lin CP
Image-guided transplantation of single cells in the bone marrow of live animals.
Sci Rep. 2017;7(1):3875 - PMID: 28634334 - PMCID: PMC5478633 - DOI: 10.1038/s41598-017-02896-6
Iaconelli J, Lalonde J, Watmuff B, Liu B, Mazitschek R, Haggarty SJ, Karmacharya R
Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells.
ACS Chem Biol. 2017;12(8):2139-2148 - PMID: 28628306 - DOI: 10.1021/acschembio.6b01014
Chousterman BG, Swirski FK, Weber GF
Cytokine storm and sepsis disease pathogenesis.
Semin Immunopathol. 2017;39(5):517-528 - PMID: 28555385 - DOI: 10.1007/s00281-017-0639-8
Conrad C, Dorzweiler K, Miller MA, Lauffenburger DA, Strik H, Bartsch JW
Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.
Fluids Barriers CNS. 2017;14(1):22 - PMID: 28806983 - PMCID: PMC5556623 - DOI: 10.1186/s12987-017-0070-5
Krukowski K, Ma J, Golonzhka O, Laumet GO, Gutti T, van Duzer JH, Mazitschek R, Jarpe MB, Heijnen CJ, Kavelaars A
HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy.
Pain. 2017;158(6):1126-1137 - PMID: 28267067 - PMCID: PMC5435512 - DOI: 10.1097/j.pain.0000000000000893
Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK
Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study.
J Am Heart Assoc. 2017;6(11):e006241 - PMID: 29092845 - PMCID: PMC5721742 - DOI: 10.1161/JAHA.117.006241
Park YI, Kim E, Huang CH, Park KS, Castro CM, Lee H, Weissleder R
Facile Coating Strategy to Functionalize Inorganic Nanoparticles for Biosensing
Bioconjug Chem. 2017;28(1):33-37 - PMID: 27792877 - PMCID: PMC5474933 - DOI: 10.1021/acs.bioconjchem.6b00524
Nairz M, Theurl I, Swirski FK, Weiss G
"Pumping iron" - how macrophages handle iron at the systemic, microenvironmental, and cellular levels.
Pflugers Arch. 2017;469(3-4):397-418 - PMID: 28251312 - PMCID: PMC5362662 - DOI: 10.1007/s00424-017-1944-8
Stiekema LCA, Schnitzler JG, Nahrendorf M, Stroes ESG
The maturation of a 'neural-hematopoietic' inflammatory axis in cardiovascular disease.
Curr Opin Lipidol. 2017;28(6):507-512 - PMID: 28877089 - DOI: 10.1097/MOL.0000000000000457
Park YJ, Battistone MA, Kim B, Breton S
Relative contribution of clear cells and principal cells to luminal pH in the mouse epididymis.
Biol Reprod. 2017;96(2):366-375 - PMID: 28203710 - DOI: 10.1095/biolreprod.116.144857
Canali S, Wang CY, Zumbrennen-Bullough KB, Bayer A, Babitt JL
Bmp2 controls iron homeostasis in mice independent of Bmp6.
Am J Hematol. 2017;92(11):1204-1213 - PMID: 28815688 - DOI: 10.1002/ajh.24888
Oza AM, Tinker AV, Oaknin A, Shapira-Frommer R, McNeish IA, Swisher EM, Ray-Coquard I, Bell-McGuinn K, Coleman RL, O'Malley DM, Leary A, Chen LM, Provencher D, Ma L, Brenton JD, Konecny GE, Castro CM, Giordano H, Maloney L, Goble S, Lin KK, Sun J, Raponi M, Rolfe L, Kristeleit RS
Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2.
Gynecol Oncol. 2017;147(2):267-275 - PMID: 28882436 - DOI: 10.1016/j.ygyno.2017.08.022
Tokarz D, Cisek R, Wein MN, Turcotte R, Haase C, Yeh SA, Bharadwaj S, Raphael AP, Paudel H, Alt C, Liu TM, Kronenberg HM, Lin CP
Intravital imaging of osteocytes in mouse calvaria using third harmonic generation microscopy.
PLoS ONE. 2017;12(10):e0186846 - PMID: 29065178 - PMCID: PMC5655444 - DOI: 10.1371/journal.pone.0186846
Arystarkhova E, Bouley R, Liu YB, Sweadner KJ
Impaired AQP2 trafficking in Fxyd1 knockout mice: A role for FXYD1 in regulated vesicular transport.
PLoS ONE. 2017;12(11):e0188006 - PMID: 29155857 - PMCID: PMC5695786 - DOI: 10.1371/journal.pone.0188006
Menezes TP, Hill E, de Alencar Moura A, Lobo MDP, Monteiro-Moreira ACO, Breton S, Machado-Neves M
Pattern of protein expression in the epididymis of Oligoryzomys nigripes (Cricetidae, Sigmodontinae).
Cell Tissue Res. 2017;:ePub - PMID: 29119327 - DOI: 10.1007/s00441-017-2714-9
Mamuya FA, Xie D, Lei L, Huang M, Tsuji K, Capen DE, Yang B, Weissleder R, Păunescu TG, Lu HJ
Deletion of β-1 integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis.
Am J Physiol Renal Physiol. 2017;:ajprenal.00038.2017 - PMID: 28701310 - PMCID: PMC5668581 - DOI: 10.1152/ajprenal.00038.2017
Cheung PW, Ueberdiek L, Day J, Bouley R, Brown D
Protein phosphatase 2C (PP2C) is responsible for VP-induced dephosphorylation of AQP2 serine 261.
Am J Physiol Renal Physiol. 2017;:ajprenal.00004.2017 - PMID: 28381458 - PMCID: PMC5582913 - DOI: 10.1152/ajprenal.00004.2017
Noiret L, Slater A, Higgins JM
Determinants of red blood cell alloantibody detection duration: analysis of multiply alloimmunized patients supports peritransfusion factors.
Transfusion. 2017;57(8):1930-1937 - PMID: 28639314 - DOI: 10.1111/trf.14157
Li YX, Gautam V, Brüstle A, Cockburn IA, Daria VR, Gillespie C, Gaus K, Alt C, Lee WM
Flexible polygon-mirror based laser scanning microscope platform for multiphoton in-vivo imaging.
J Biophotonics. 2017;10(11):1526-1537 - PMID: 28164461 - DOI: 10.1002/jbio.201600289
Im H, Yang K, Lee H, Castro CM
Characterization of Extracellular Vesicles by Surface Plasmon Resonance.
Methods Mol Biol. 2017;1660:133-141 - PMID: 28828653 - DOI: 10.1007/978-1-4939-7253-1_11
Conrad C, Miller MA, Bartsch JW, Schlomann U, Lauffenburger DA
Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.
Methods Mol Biol. 2017;1574:243-253 - PMID: 28315256 - DOI: 10.1007/978-1-4939-6850-3_18
Pérez-Medina C, Hak S, Reiner T, Fayad ZA, Nahrendorf M, Mulder WJM
Integrating nanomedicine and imaging.
Philos Trans A Math Phys Eng Sci. 2017;375(2107):ePub - PMID: 29038380 - PMCID: PMC5647268 - DOI: 10.1098/rsta.2017.0110
Yoneyama T, Gorry M, Miller MA, Gaither-Davis A, Lin Y, Moss ML, Griffith LG, Lauffenburger DA, Stabile LP, Herman JG, Vujanovic NL
Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates.
J Cancer. 2017;8(19):3916-3932 - PMID: 29187866 - PMCID: PMC5705993 - DOI: 10.7150/jca.20779
Randino R, Gazzerro P, Mazitschek R, Rodriquez M
Synthesis and biological evaluation of Santacruzamate-A based analogues.
Bioorg Med Chem. 2017;25(24):6486-6491 - PMID: 29100734 - DOI: 10.1016/j.bmc.2017.10.026
Pera V, Tan X, Runnels J, Sardesai N, Lin CP, Niedre M
Diffuse fluorescence fiber probe for in vivo detection of circulating cells.
J Biomed Opt. 2017;22(3):37004 - PMID: 28290598 - PMCID: PMC5348644 - DOI: 10.1117/1.JBO.22.3.037004
Lee S, Courties G, Nahrendorf M, Weissleder R, Vinegoni C
Motion characterization scheme to minimize motion artifacts in intravital microscopy.
J Biomed Opt. 2017;22(3):36005 - PMID: 28253383 - PMCID: PMC5333764 - DOI: 10.1117/1.JBO.22.3.036005
Hartmann C, Patil R, Lin CP, Niedre M
Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects.
Phys Med Biol. 2017;63(1):01TR01 - PMID: 29240559 - PMCID: PMC5753400 - DOI: 10.1088/1361-6560/aa98f9
Hartmann C, Patil R, Lin CP, Niedre MJ
Fluorescence detection, enumeration and characterization of single circulating cells in vivo technology, applications and future prospects.
Phys Med Biol. 2017;:ePub - PMID: 29115281 - DOI: 10.1088/1361-6560/aa98f9
Brown D
The Discovery of Water Channels (Aquaporins).
Ann Nutr Metab. 2017;70 Suppl 1:37-42 - PMID: 28614812 - DOI: 10.1159/000463061
Lu X, Galarneau MM, Higgins JM, Wood DK
A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow.
Microcirculation. 2017;:ePub - PMID: 28129479 - PMCID: PMC5505799 - DOI: 10.1111/micc.12357
Je KH, Ryu WS, Lee SK, Kim EJ, Kim JY, Jang HJ, Park JE, Nahrendorf M, Schellingerhout D, Kim DE
Green-channel autofluorescence imaging: A novel and sensitive technique to delineate infarcts.
J Neurosci Methods. 2017;279:22-32 - PMID: 28104485 - DOI: 10.1016/j.jneumeth.2017.01.007
Shen S, Ding W, Ahmed S, Hu R, Opalacz A, Roth S, You Z, Wojtkiewicz GR, Lim G, Chen L, Mao J, Chen JW, Zhang Y
Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions.
Pain Med. 2017;:ePub - PMID: 29177411 - DOI: 10.1093/pm/pnx267
Soeken TA, Zhu H, DeMartelaere S, Davies BW, Kim M, Wang HC, Aden J, Grimm R, Alt C, Kochevar IE, Johnson AJ
Sealing of Corneal Lacerations Using Photoactivated Rose Bengal Dye and Amniotic Membrane.
Cornea. 2017;37(2):211-217 - PMID: 29140861 - DOI: 10.1097/ICO.0000000000001389
Vieson MD, Gojmerac AM, Khan D, Dai R, van Duzer JH, Mazitschek R, Caudell DL, Liao X, Luo XM, Reilly CM
Treatment with a selective histone deacetylase 6 inhibitor decreases lupus nephritis in NZB/W mice.
Histol Histopathol. 2017;:11885 - PMID: 28245046 - DOI: 10.14670/HH-11-885
Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK
Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography.
Coron Artery Dis. 2017;28(7):557-563 - PMID: 28704243 - DOI: 10.1097/MCA.0000000000000534
Dev S, Babitt JL
Overview of iron metabolism in health and disease.
Hemodial Int. 2017;21 Suppl 1:S6-S20 - PMID: 28296010 - DOI: 10.1111/hdi.12542
Shon SM, Jang HJ, Schellingerhout D, Kim JY, Ryu WS, Lee SK, Kim J, Park JY, Oh JH, Kang JW, Je KH, Park JE, Kim K, Kwon IC, Lee J, Nahrendorf M, Park JH, Kim DE
Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice.
Circ J. 2017;81(10):1528-1536 - PMID: 28883215 - DOI: 10.1253/circj.CJ-16-1196
Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR
Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer.
Sci Adv. 2017;3(6):e1700341 - PMID: 28630930 - PMCID: PMC5473678 - DOI: 10.1126/sciadv.1700341
Christensen HL, Păunescu TG, Matchkov V, Barbuskaite D, Brown D, Damkier HH, Praetorius J
The V-ATPase is expressed in the choroid plexus and mediates cAMP-induced intracellular pH alterations.
Physiol Rep. 2017;5(1):ePub - PMID: 28053225 - PMCID: PMC5256157 - DOI: 10.14814/phy2.13072
Kim SJ, Zhao B, Im H, Min J, Choi N, Castro CM, Weissleder R, Lee H, Lee K
Deep-learning based hologram classification for molecular diagnostics
bioRxiv. 2017;192559:ePub - DOI: 10.1101/192559
Miller MA, Arlauckas S, Weissleder R
Prediction of Anti-cancer Nanotherapy Efficacy by Imaging
Nanotheranostics. 2017;1(3):296-312 - PMID: 29071194 - PMCID: PMC5646731 - DOI: 10.7150/ntno.20564
Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, Francis JM, Patel AA, Onozato ML, Riggi N, Livak KJ, Gennert D, Satija R, Nahed BV, Curry WT, Martuza RL, Mylvaganam R, Iafrate AJ, Frosch MP, Golub TR, Rivera MN, Getz G, Rozenblatt-Rosen O, Cahill DP, Monje M, Bernstein BE, Louis DN, Regev A, Suvà ML
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.
Nature. 2016;539(7628):309-313 - PMID: 27806376 - PMCID: PMC5465819 - DOI: 10.1038/nature20123
Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Golan K, Khatib E, Kumari A, Kollet O, Shakhar G, Butler JM, Rafii S, Adams RH, Scadden DT, Lin CP, Lapidot T
Distinct bone marrow blood vessels differentially regulate haematopoiesis.
Nature. 2016;532(7599):323-328 - PMID: 27074509 - DOI: 10.1038/nature17624
Wang X, Lee RS, Alver BH, Haswell JR, Wang S, Mieczkowski J, Drier Y, Gillespie SM, Archer TC, Wu JN, Tzvetkov EP, Troisi EC, Pomeroy SL, Biegel JA, Tolstorukov MY, Bernstein BE, Park PJ, Roberts CW
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation.
Nat Genet. 2016;49(2):289-295 - PMID: 27941797 - PMCID: PMC5285474 - DOI: 10.1038/ng.3746
Drier Y, Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L, Qi J, Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster JC, Knoechel B, Bernstein BE
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.
Nat Genet. 2016;48(3):265-72 - PMID: 26829750 - PMCID: PMC4767593 - DOI: 10.1038/ng.3502
Engblom C, Pfirschke C, Pittet MJ
The role of myeloid cells in cancer therapies.
Nat Rev Cancer. 2016;16(7):447-62 - PMID: 27339708 - DOI: 10.1038/nrc.2016.54
Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Cell. 2016;167(5):1310-1322.e17 - PMID: 27863245 - DOI: 10.1016/j.cell.2016.10.045
Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, Pittet MJ
SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions
Science. 2016;352(6282):242-246 - PMID: 26989197 - PMCID: PMC4960636 - DOI: 10.1126/science.aaf1328
Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, Suda T, Lin CP, Frenette PS, Ito K
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.
Science. 2016;354(6316):1156-1160 - PMID: 27738012 - PMCID: PMC5164878 - DOI: 10.1126/science.aaf5530
Shema E, Jones D, Shoresh N, Donohue L, Ram O, Bernstein BE
Single-molecule decoding of combinatorially modified nucleosomes.
Science. 2016;352(6286):717-21 - PMID: 27151869 - PMCID: PMC4904710 - DOI: 10.1126/science.aad7701
Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
Nature Med. 2016;22(8):945-951 - PMID: 27428900 - PMCID: PMC4957133 - DOI: 10.1038/nm.4146
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.
Cell Stem Cell. 2016;19(4):530-543 - PMID: 27524439 - PMCID: PMC5402355 - DOI: 10.1016/j.stem.2016.07.004
Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Cell Stem Cell. 2016;20(2):233-246.e7 - PMID: 27989769 - PMCID: PMC5291795 - DOI: 10.1016/j.stem.2016.11.003
Pfirschke C, Engblom C, Rickelt S, Cortez-Retamozo V, Garris C, Pucci F, Yamasaki T, Poirier-Colame V, Newton A, Redouane Y, Lin YJ, Wojtkiewicz G, Iwamoto Y, Mino-Kenudson M, Huynh TG, Hynes RO, Freeman GJ Kroemer G, Zitvogel L, Weissleder R, Pittet MJ
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
Immunity. 2016;44:1-12 - PMID: 26872698 - PMCID: PMC4758865 - DOI: 10.1016/j.immuni.2015.11.024
Siwicki M, Engblom C, Pittet MJ
Gal3 Links Inflammation and Insulin Resistance.
Cell Metab. 2016;24(5):655-656 - PMID: 27829136 - DOI: 10.1016/j.cmet.2016.10.014
Malka R, Nathan DM, Higgins JM
Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring
Sci Transl Med. 2016;8:359ra130 - PMID: 27708063 - PMCID: PMC5714656 - DOI: 10.1126/scitranslmed.aaf9304
Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction
Sci Transl Med. 2016;8:342 - PMID: 27280687 - Cover
Castro CM
Taking cancer drug screening very personally.
Sci Transl Med. 2016;8(367):367ec190 - PMID: 27903858 - DOI: 10.1126/scitranslmed.aal2799
Weissleder R, Schwaiger MC, Gambhir SS, Hricak H
Imaging approaches to optimize molecular therapies
Sci Transl Med. 2016;8(355):355ps16 - PMID: 27605550 - DOI: 10.1126/scitranslmed.aaf3936
Miller MA, Weissleder R
Imaging the pharmacology of nanomaterials by intravital microscopy: Towards understanding their biological behavior.
Adv Drug Deliv Rev. 2016;113:61-86 - PMID: 27266447 - PMCID: PMC5136524 - DOI: 10.1016/j.addr.2016.05.023
van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.
Mol Cell. 2016;61(1):170-80 - PMID: 26687680 - PMCID: PMC4707994 - DOI: 10.1016/j.molcel.2015.11.003
van der Valk FM, Kuijk C, Verweij SL, Stiekema LC, Kaiser Y, Zeerleder S, Nahrendorf M, Voermans C, Stroes ES
Increased haematopoietic activity in patients with atherosclerosis.
Eur Heart J. 2016;38(6):425-432 - PMID: 27357356 - DOI: 10.1093/eurheartj/ehw246
Frodermann V, Nahrendorf M
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2016;:ePub - PMID: 26984866
Hong S, Pirovich D, Kilcoyne A, Huang CH, Lee H, Weissleder R
Supramolecular Metallo-Bioadhesive for Minimally Invasive Use
Adv Mater. 2016;28(39):8675-8680 - PMID: 27515068 - PMCID: PMC5144581 - DOI: 10.1002/adma.201602606
Libby P, Nahrendorf M, Swirski FK
Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum"
J Am Coll Cardiol. 2016;67(9):1091-103 - PMID: 26940931 - PMCID: PMC4779182 - DOI: 10.1016/j.jacc.2015.12.048
Reis SA, Ghosh B, Hendricks JA, Szantai-Kis DM, Törk L, Ross KN, Lamb J, Read-Button W, Zheng B, Wang H, Salthouse C, Haggarty SJ, Mazitschek R
Light-controlled modulation of gene expression by chemical optoepigenetic probes.
Nat Chem Biol. 2016;12(5):317-323 - PMID: 26974814 - PMCID: PMC4836974 - DOI: 10.1038/nchembio.2042
Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R
Quantitating drug-target engagement in single cells in vitro and in vivo.
Nat Chem Biol. 2016;13(2):168-173 - PMID: 27918558 - PMCID: PMC5630128 - DOI: 10.1038/nchembio.2248
Xie Q, Wu Q, Kim L, Miller TE, Liau BB, Mack SC, Yang K, Factor DC, Fang X, Huang Z, Zhou W, Alazem K, Wang X, Bernstein BE, Bao S, Rich JN
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.
J Clin Invest. 2016;126(7):2757-72 - PMID: 27322055 - PMCID: PMC4922685 - DOI: 10.1172/JCI86114
Jeong S, Park J, Pathania D, Castro CM, Weissleder R, Lee H
Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
ACS Nano. 2016;10(2):1802-1809 - PMID: 26808216 - PMCID: PMC4802494 - DOI: 10.1021/acsnano.5b07584
Mattoo H, Mahajan VS, Maehara T, Deshpande V, Della-Torre E, Wallace ZS, Kulikova M, Drijvers JM, Daccache J, Carruthers MN, Castellino F, Stone JR, Stone JH, Pillai S
Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
J Allergy Clin Immunol. 2016;138(3):825-38 - PMID: 26971690 - PMCID: PMC5014627 - DOI: 10.1016/j.jaci.2015.12.1330
McAlpine CS, Swirski FK
Circadian Influence on Metabolism and Inflammation in Atherosclerosis.
Circ Res. 2016;119(1):131-41 - PMID: 27340272 - PMCID: PMC4922503 - DOI: 10.1161/CIRCRESAHA.116.308034
Swirski FK, Nahrendorf M
Bone Marrow Takes Center Stage in Cardiovascular Disease.
Circ Res. 2016;119(6):701-3 - PMID: 27587406 - PMCID: PMC5012290 - DOI: 10.1161/CIRCRESAHA.116.309584
Sager HB, Hulsmans M, Lavine KJ, Beltrami Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Circ Res. 2016;119(7):853-64 - PMID: 27444755 - PMCID: PMC5378496 - DOI: 10.1161/CIRCRESAHA.116.309001
Nahrendorf M, Swirski FK
Abandoning M1/M2 for a Network Model of Macrophage Function.
Circ Res. 2016;119(3):414-7 - PMID: 27458196 - PMCID: PMC4965179 - DOI: 10.1161/CIRCRESAHA.116.309194
Corey KE, Kartoun U, Zheng H, Chung RT, Shaw SY
Using an Electronic Medical Records Database to Identify Non-Traditional Cardiovascular Risk Factors in Nonalcoholic Fatty Liver Disease.
Am J Gastroenterol. 2016;111(5):671-6 - PMID: 26925881 - PMCID: PMC4864030 - DOI: 10.1038/ajg.2016.44
Chen YC, Backus KM, Merkulova M, Yang C, Brown D, Cravatt BF, Zhang C
Covalent Modulators of the Vacuolar ATPase.
J Am Chem Soc. 2016;139(2):639-642 - PMID: 28010062 - PMCID: PMC5274637 - DOI: 10.1021/jacs.6b12511
Goyal L, Saha SK, Liu LY, Siravegna G, Leshchiner I, Ahronian LG, Lennerz JK, Vu P, Deshpande V, Kambadakone A, Mussolin B, Reyes S, Henderson L, Sun JE, Van Seventer EE, Gurski JM, Baltschukat S, Schacher-Engstler B, Barys L, Stamm C, Furet P, Ryan DP, Stone JR, Iafrate AJ, Getz G, Graus Porta D, Tiedt R, Bardelli A, Juric D, Corcoran RB, Bardeesy N, Zhu AX
Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma.
Cancer Discov. 2016;7(3):252-263 - PMID: 28034880 - PMCID: PMC5433349 - DOI: 10.1158/2159-8290.CD-16-1000
Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, Raulet DH, Weinberg RA
Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells.
Cancer Discov. 2016;6(6):630-49 - PMID: 27072748 - PMCID: PMC4918202 - DOI: 10.1158/2159-8290.CD-15-1157
Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
Cancer Discov. 2016;6(4):382-99 - PMID: 26984351 - PMCID: PMC5087317 - DOI: 10.1158/2159-8290.CD-15-0933 - Cover
Aryal B, Rotllan N, Araldi E, Ramírez CM, He S, Chousterman BG, Fenn AM, Wanschel A, Madrigal-Matute J, Warrier N, Martín-Ventura JL, Swirski FK, Suárez Y, Fernández-Hernando C
ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Nat Commun. 2016;7:12313 - PMID: 27460411 - PMCID: PMC4974469 - DOI: 10.1038/ncomms12313
Vinegoni C, Leon Swisher C, Fumene Feruglio P, Giedt RJ, Rousso DL, Stapleton S, Weissleder R
Real-time high dynamic range laser scanning microscopy.
Nat Commun. 2016;7:11077 - PMID: 27032979 - PMCID: PMC4821995 - DOI: 10.1038/ncomms11077
Roy J*, Kim B*, Hill E, Visconti P, Krapf D, Vinegoni C, Weissleder R, Brown D, Breton S
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging.
Nat Commun. 2016;7:10666 - PMID: 26868824 - PMCID: PMC4754344 - DOI: 10.1038/ncomms10666
Kirschbaum K, Sonner JK, Zeller MW, Deumelandt K, Bode J, Sharma R, Krüwel T, Fischer M, Hoffmann A, Costa da Silva M, Muckenthaler MU, Wick W, Tews B, Chen JW, Heiland S, Bendszus M, Platten M, Breckwoldt MO
In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.
Proc Natl Acad Sci U S A. 2016;113(46):13227-13232 - PMID: 27799546 - PMCID: PMC5135308 - DOI: 10.1073/pnas.1609397113
Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Proc Natl Acad Sci U S A. 2016;113(44):E6731-E6740 - PMID: 27791119 - PMCID: PMC5098679 - DOI: 10.1073/pnas.1609629113
Hideshima T, Qi J, Paranal RM, Tang W, Greenberg E, West N, Colling ME, Estiu G, Mazitschek R, Perry JA, Ohguchi H, Cottini F, Mimura N, Görgün G, Tai YT, Richardson PG, Carrasco RD, Wiest O, Schreiber SL, Anderson KC, Bradner JE
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.
Proc Natl Acad Sci U S A. 2016;113(46):13162-13167 - PMID: 27799547 - PMCID: PMC5135369 - DOI: 10.1073/pnas.1608067113
Ramasamy S, Saez B, Mukhopadhyay S, Ding D, Ahmed AM, Chen X, Pucci F, Yamin R, Wang J, Pittet MJ, Kelleher CM, Scadden DT, Sweetser DA
Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway.
Proc Natl Acad Sci U S A. 2016;113(7):1871-6 - PMID: 26831087 - PMCID: PMC4763742 - DOI: 10.1073/pnas.1511380113
Hosseini P, Abidi SZ, Du E, Papageorgiou DP, Choi Y, Park Y, Higgins JM, Kato GJ, Suresh S, Dao M, Yaqoob Z, So PT
Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease.
Proc Natl Acad Sci U S A. 2016;113(34):9527-32 - PMID: 27512047 - PMCID: PMC5003247 - DOI: 10.1073/pnas.1610435113
Swirski FK, Robbins CS, Nahrendorf M
Development and Function of Arterial and Cardiac Macrophages.
Trends Immunol. 2016;37(1):32-40 - PMID: 26748179 - PMCID: PMC4706986 - DOI: 10.1016/j.it.2015.11.004
Canali S, Zumbrennen-Bullough KB, Core AB, Wang CY, Nairz M, Bouley R, Swirski FK, Babitt JL
Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Blood. 2016;129(4):405-414 - PMID: 27864295 - PMCID: PMC5270389 - DOI: 10.1182/blood-2016-06-721571
Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D
Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
Blood. 2016;127(19):2327-36 - PMID: 26755707 - PMCID: PMC4865590 - DOI: 10.1182/blood-2015-11-681494
Trepiccione F, Gerber SD, Grahammer F, López-Cayuqueo KI, Baudrie V, Păunescu TG, Capen DE, Picard N, Alexander RT, Huber TB, Chambrey R, Brown D, Houillier P, Eladari D, Simons M
Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.
J Am Soc Nephrol. 2016;27(11):3320-3330 - PMID: 27044666 - PMCID: PMC5084887 - DOI: 10.1681/ASN.2015080915
Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Jenny Lu HA, Brown D, Bouley R
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
J Am Soc Nephrol. 2016;:ePub - PMID: 26961350 - DOI: 10.1681/ASN.2015080903
Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Lu HA, Brown D, Bouley R
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
J Am Soc Nephrol. 2016;27(10):3105-3116 - PMID: 27694161 - PMCID: PMC5042667 - DOI: 10.1681/ASN.2015080903
Mumtaz R, Trepiccione F, Hennings JC, Huebner AK, Serbin B, Picard N, Ullah AK, Păunescu TG, Capen DE, Lashhab RM, Mouro-Chanteloup I, Alper SL, Wagner CA, Cordat E, Brown D, Eladari D, Hübner CA
Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an AE1 R607H Knockin Model.
J Am Soc Nephrol. 2016;28(5):1507-1520 - PMID: 27932475 - PMCID: PMC5407715 - DOI: 10.1681/ASN.2016020169
Pathania D*, Im H*, Kilcoyne A, Sohani AR, Fexon L, Pivovarov M, Abramson JS, Randall TC, Chabner BA, Weissleder R, Lee H, Castro CM
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Theranostics. 2016;6(10):1603-10 - PMID: 27446494 - PMCID: PMC4955059 - DOI: 10.7150/thno.15534
Ricklefs F, Mineo M, Rooj AK, Nakano I, Charest A, Weissleder R, Breakefield XO, Chiocca EA, Godlewski J, Bronisz A
Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity.
Cancer Res. 2016;76(10):2876-2881 - PMID: 27013191 - PMCID: PMC4873326 - DOI: 10.1158/0008-5472.CAN-15-3432
Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.
Kidney Int. 2016;1(3):135-143 - PMID: 27990496 - PMCID: PMC5155703 - DOI: 10.1016/j.ekir.2016.06.006
Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M
Glucagon-like peptide-1 receptor activation attenuates platelet aggregation and thrombosis.
Diabetes. 2016;65(6):1714-23 - PMID: 26936963 - DOI: 10.2337/db15-1141
Gainor JF, Shaw AT, Sequist LV, Fu X, Azzoli CG, Piotrowska Z, Huynh TG, Zhao L, Fulton L, Schultz K, Howe E, Farago AF, Sullivan RJ, Stone JR, Digumarthy S, Moran T, Hata AN, Yagi Y, Yeap BY, Engelman JA, Mino-Kenudson M
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer (NSCLC): A Retrospective Analysis.
Clin Cancer Res. 2016;22(18):4585-93 - PMID: 27225694 - PMCID: PMC5026567 - DOI: 10.1158/1078-0432.CCR-15-3101
Miller MA, Sullivan RJ, Lauffenburger DA
Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.
Clin Cancer Res. 2016;23(3):623-629 - PMID: 27895032 - PMCID: PMC5290119 - DOI: 10.1158/1078-0432.CCR-16-0869
Dykstra B, Lee J, Mortensen LJ, Yu H, Wu ZL, Lin CP, Rossi DJ, Sackstein R
Glycoengineering of E-selectin ligands by intracellular versus extracellular fucosylation differentially affects osteotropism of human mesenchymal stem cells.
Stem Cells. 2016;34(10):2501-2511 - PMID: 27335219 - PMCID: PMC5064874 - DOI: 10.1002/stem.2435
Gee MS, Ghazani AA, Haq R, Wargo JA, Sebas M, Sullivan RJ, Lee H, Weissleder R
Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood.
Nanomedicine. 2016;13(3):821-828 - PMID: 27993725 - PMCID: PMC5392428 - DOI: 10.1016/j.nano.2016.12.006
Pucci F, Rickelt S, Newton AP, Garris C, Nunes E, Evavold C, Pfirschke C, Engblom C, Mino-Kenudson M, Hynes RO, Weissleder R, Pittet MJ
PF4 Promotes Platelet Production and Lung Cancer Growth.
Cell Rep. 2016;17(7):1764-1772 - PMID: 27829148 - PMCID: PMC5108525 - DOI: 10.1016/j.celrep.2016.10.031
Reckelhoff JF, Brown D, Molina PE
APS Takes a Look in the Mirror.
Physiology (Bethesda). 2016;31(6):384-385 - PMID: 27708041 - DOI: 10.1152/physiol.00023.2016
Hall JL, Ryan JJ, Bray BE, Brown C, Lanfear D, Newby LK, Relling MV, Risch NJ, Roden DM, Shaw SY, Tcheng JE, Tenenbaum J, Wang TN, Weintraub WS
Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association.
Circ Cardiovasc Genet. 2016;9(2):193-202 - PMID: 26976545 - PMCID: PMC5646218 - DOI: 10.1161/HCG.0000000000000029
Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F
Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
Circ Heart Fail. 2016;9(1):e002724 - PMID: 26721917 - PMCID: PMC4698901 - DOI: 10.1161/CIRCHEARTFAILURE.115.002724
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I
Statin use is Associated With Reduced Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2016;14(7):973-9 - PMID: 26905907 - PMCID: PMC4912917 - DOI: 10.1016/j.cgh.2016.02.017
Huang P, Almeciga-Pinto I, Jarpe M, van Duzer JH, Mazitschek R, Yang M, Jones SS, Quayle SN
Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.
Oncotarget. 2016;8(2):2694-2707 - PMID: 27926524 - PMCID: PMC5356834 - DOI: 10.18632/oncotarget.13738
Cotter K, Liberman R, Sun-Wada G, Wada Y, Sgroi D, Naber S, Brown D, Breton S, Forgac M
The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.
Oncotarget. 2016;7(29):46142-46157 - PMID: 27323815 - PMCID: PMC5216787 - DOI: 10.18632/oncotarget.10063
Albadawi H, Chen JW, Oklu R, Wu Y, Wojtkiewicz G, Pulli B, Milner JD, Cambria RP, Watkins MT
Spinal Cord Inflammation: Molecular Imaging after Thoracic Aortic Ischemia Reperfusion Injury.
Radiology. 2016;:152222 - PMID: 27509542 - PMCID: PMC5207124 - DOI: 10.1148/radiol.2016152222
Babaev VR, Ding L, Zhang Y, May JM, Lin CP, Fazio S, Linton MF
Macrophage IκB Kinase α Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2016;36(4):598-607 - PMID: 26848161 - PMCID: PMC4808396 - DOI: 10.1161/ATVBAHA.115.306931
Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK
Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study.
Arterioscler Thromb Vasc Biol. 2016;36(11):2229-2238 - PMID: 27634834 - DOI: 10.1161/ATVBAHA.116.307891
Dutta P, Hoyer FF, Sun Y, Iwamoto Y, Tricot B, Weissleder R, Magnani JL, Swirski FK, Nahrendorf M
E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial Infarction.
Arterioscler Thromb Vasc Biol. 2016;36(9):1802-8 - PMID: 27470513 - PMCID: PMC5001901 - DOI: 10.1161/ATVBAHA.116.307519
Calcagno C, Mulder WJ, Nahrendorf M, Fayad ZA
Systems Biology and Noninvasive Imaging of Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2016;36(2):e1-8 - PMID: 26819466 - PMCID: PMC4861402 - DOI: 10.1161/ATVBAHA.115.306350
Meimetis LG, Giedt R, Mikyla H, Carlson J, Kohler R, Pirovich DB, Weissleder R
Fluorescent vinblastine probes for live cell imaging
Chem Commun. 2016;52(64):9953-6 - PMID: 27439765 - PMCID: PMC4970878 - DOI: 10.1039/c6cc04129a
Im H, Park YI, Pathania D, Castro CM, Weissleder R, Lee H
Digital diffraction detection of protein markers for avian influenza.
Lab Chip. 2016;16(8):1340-5 - PMID: 26980325 - PMCID: PMC4829473 - DOI: 10.1039/c5lc01558h
Lindau A, Härdtner C, Hergeth SP, Blanz KD, Dufner B, Hoppe N, Anto-Michel N, Kornemann J, Zou J, Gerhardt LM, Heidt T, Willecke F, Geis S, Stachon P, Wolf D, Libby P, Swirski FK, Robbins CS, McPheat W, Hawley S, Braddock M, Gilsbach R, Hein L, von Zur Mühlen C, Bode C, Zirlik A, Hilgendorf I
Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.
Basic Res Cardiol. 2016;111(2):20 - PMID: 26891724 - PMCID: PMC4759214 - DOI: 10.1007/s00395-016-0535-8
Rischpler C, Dirschinger RJ, Nekolla SG, Kossmann H, Nicolosi S, Hanus F, van Marwick S, Kunze KP, Meinicke A, Götze K, Kastrati A, Langwieser N, Ibrahim T, Nahrendorf M, Schwaiger M, Laufwitz KL
Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome
Circ Cardiovasc Imaging. 2016;9:e004316 - PMID: 27056601 - PMCID: PMC4826716 - DOI: 10.1161/CIRCIMAGING.115.004316
Kilcoyne A, Harisinghani MG, Mahmood U
Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles.
J Nucl Med. 2016;57(Suppl 3):105S-110S - PMID: 27694162 - DOI: 10.2967/jnumed.115.170738
Vunnam S, Reddy A, Mazitschek R, Lukens AK, Wirth DF, Li L, Naumov P, O'Connor MJ, Al-Tel TH
Intramolecular Diaza-Diels-Alder Protocol: A Novel Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.
Chemistry. 2016;23(17):4137-4148 - PMID: 27997727 - DOI: 10.1002/chem.201605231
Oudin MJ, Barbier L, Schäfer C, Kosciuk T, Miller MA, Han S, Jonas O, Lauffenburger DA, Gertler FB
MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.
Mol Cancer Ther. 2016;16(1):143-155 - PMID: 27811011 - PMCID: PMC5359014 - DOI: 10.1158/1535-7163.MCT-16-0413
Yang Z, Concannon J, Ng KS, Seyb K, Mortensen LJ, Ranganath S, Gu F, Levy O, Tong Z, Martyn K, Zhao W, Lin CP, Glicksman MA, Karp JM
Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation.
Sci Rep. 2016;6:30263 - PMID: 27457881 - PMCID: PMC4960598 - DOI: 10.1038/srep30263
Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC
A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever.
Sci Rep. 2016;6:32878 - PMID: 27605393 - PMCID: PMC5015101 - DOI: 10.1038/srep32878
Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R
Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response
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Song J, Leon Swisher C, Im H, Jeong S, Pathania D, Iwamoto Y, Pivovarov M, Weissleder R, Lee H
Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography.
Sci Rep. 2016;6:24681 - PMID: 27098438 - PMCID: PMC4838824 - DOI: 10.1038/srep24681
Wu JW, Turcotte R, Alt C, Runnels JM, Tsao H, Lin CP
Defining Clonal Color in Fluorescent Multi-Clonal Tracking
Sci Rep. 2016;6:24303 - PMID: 27073117 - PMCID: PMC4829845 - DOI: 10.1038/srep24303
Ng EX, Miller MA, Jing T, Chen CH
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Biosens Bioelectron. 2016;81:408-14 - PMID: 26995287 - DOI: 10.1016/j.bios.2016.03.002
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN
Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis.
Inflamm Bowel Dis. 2016;22(4):880-885 - PMID: 26933751 - PMCID: PMC4792716 - DOI: 10.1097/MIB.0000000000000754
Secemsky EA, Butala NM, Kartoun U, Mahmood S, Wasfy JH, Kennedy KF, Shaw SY, Yeh RW
Use of Chronic Oral Anticoagulation and Associated Outcomes Among Patients Undergoing Percutaneous Coronary Intervention.
J Am Heart Assoc. 2016;5(10):ePub - PMID: 27792650 - PMCID: PMC5121523 - DOI: 10.1161/JAHA.116.004310
Canali S, Core AB, Zumbrennen-Bullough KB, Merkulova M, Wang CY, Schneyer A, Pietrangelo A, Babitt JL
Activin B induces noncanonical SMAD1/5/8 signaling via BMP type I receptors in hepatocytes: evidence for a role in hepcidin induction by inflammation in male mice.
Endocrinology. 2016;:en20151747 - PMID: 26735394 - PMCID: PMC4769363 - DOI: 10.1210/en.2015-1747
Canali S, Vecchi C, Garuti C, Montosi G, Babitt JL, Pietrangelo A
The SMAD pathway is required for hepcidin response during endoplasmic reticulum stress.
Endocrinology. 2016;:en20161258 - PMID: 27483343 - PMCID: PMC5045507 - DOI: 10.1210/en.2016-1258
Oudin MJ, Miller MA, Klazen JA, Kosciuk T, Lussiez A, Hughes SK, Tadros J, Bear JE, Lauffenburger DA, Gertler FB
MenaINV mediates synergistic crosstalk between signaling pathways driving chemotaxis and haptotaxis.
Mol Biol Cell. 2016;27(20):3085-3094 - PMID: 27559126 - PMCID: PMC5063616 - DOI: 10.1091/mbc.E16-04-0212
Bozhko D, Osborn EA, Rosenthal A, Verjans JW, Hara T, Kellnberger S, Wissmeyer G, Ovsepian SV, McCarthy JR, Mauskapf A, Stein AF, Jaffer FA, Ntziachristos V
Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo.
Eur Heart J Cardiovasc Imaging. 2016;18(11):1253-1261 - PMID: 28031233 - DOI: 10.1093/ehjci/jew222
Liu J, Wang W, Liu M, Su L, Zhou H, Xia Y, Ran J, Lin HY, Yang B
Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.
Cell Signal. 2016;28(12):1842-1851 - PMID: 27575743 - DOI: 10.1016/j.cellsig.2016.08.015
Vinegoni C, Dubach JM, Feruglio PF, Weissleder R
Two-Photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement
IEEE J Sel Top Quantum Electron. 2016;22 (3):6801607 - PMID: 27440991 - PMCID: PMC4946648 - DOI: 10.1109/JSTQE.2015.2501384
Meng C, Liu W, Huang H, Wang Y, Chen B, Freeman GJ, Schneyer A, Lin HY, Xia Y
Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice.
Biol Reprod. 2016;94(4):78 - PMID: 26911425 - DOI: 10.1095/biolreprod.115.135921
Davis RW, Brannen AD, Hossain MJ, Monsma S, Bock PE, Nahrendorf M, Mead D, Lodes M, Liles MR, Panizzi P
Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains.
BMC Genomics. 2016;17(1):179 - PMID: 26940863 - PMCID: PMC4778325 - DOI: 10.1186/s12864-016-2433-8
Kim H, Wei Y, Lee JY, Wu Y, Zheng Y, Moskowitz MA, Chen JW
Myeloperoxidase inhibition increases neurogenesis after ischemic stroke.
J Pharmacol Exp Ther. 2016;359(2):262-272 - PMID: 27550713 - PMCID: PMC5074486 - DOI: 10.1124/jpet.116.235127
Wang CY, Babitt JL
Hepcidin regulation in the anemia of inflammation.
Curr Opin Hematol. 2016;23(3):189-197 - PMID: 26886082 - PMCID: PMC4993159 - DOI: 10.1097/MOH.0000000000000236
Li A, Wu Y, Linnoila J, Pulli B, Wang C, Zeller M, Ali M, Lewandrowski GK, Li J, Tricot B, Keliher E, Wojtkiewicz GR, Fulci G, Feng X, Tannous BA, Yao Z, Chen JW
Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models.
Cancer Immunol Immunther. 2016;65(12):1545-1554 - PMID: 27722909 - PMCID: PMC5101144 - DOI: 10.1007/s00262-016-1911-9
Vafai SB, Mevers E, Higgins KW, Fomina Y, Zhang J, Mandinova A, Newman D, Shaw SY, Clardy J, Mootha VK
Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.
PLoS ONE. 2016;11(9):e0162686 - PMID: 27622560 - PMCID: PMC5021346 - DOI: 10.1371/journal.pone.0162686
Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D
CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.
PLoS ONE. 2016;11(6):e0156595 - PMID: 27253518 - PMCID: PMC4890777 - DOI: 10.1371/journal.pone.0156595
Turcotte R, Mattson JM, Wu JW, Zhang Y, Lin CP
Molecular Order of Arterial Collagen Using Circular Polarization Second-Harmonic Generation Imaging.
Biophys J. 2016;110(3):530-3 - PMID: 26806883 - PMCID: PMC4744203 - DOI: 10.1016/j.bpj.2015.12.030
Lu X, Wood DK, Higgins JM
Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension.
Biophys J. 2016;110(12):2751-8 - PMID: 27332133 - PMCID: PMC4919586 - DOI: 10.1016/j.bpj.2016.04.050
David V, Francis C, Babitt JL
Ironing out the crosstalk between FGF23 and inflammation.
Am J Physiol Renal Physiol. 2016;:ajprenal.00359.2016 - PMID: 27582104 - PMCID: PMC5283889 - DOI: 10.1152/ajprenal.00359.2016
Mamuya FA, Cano-Peñalver JL, Li WU, Rodriguez-Puyol D, Rodríguez-Puyol M, Brown D, de Frutos S, Lu HJ
ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway.
Am J Physiol Renal Physiol. 2016;:ajprenal.00336.2016 - PMID: 27760768 - PMCID: PMC5210194 - DOI: 10.1152/ajprenal.00336.2016
Jeun M, Park S, Lee H, Lee KH
Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles
Int J Nanomedicine. 2016;2016:11:5497–5503 - PMID: 27799772 - PMCID: PMC5085298 - DOI: 10.2147/IJN.S118156
Turcotte R, Wu JW, Lin CP
Intravital multiphoton photoconversion with a cell membrane dye.
J Biophotonics. 2016;10(2):206-210 - PMID: 27433967 - DOI: 10.1002/jbio.201600077
Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, Wirth DF, André V, Duarte MT, Guedes RC, J V A Dos Santos D, Rosenthal PJ, Mazitschek R, Prudêncio M, Moreira R
Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
ChemMedChem. 2016;11(19):2194-2204 - PMID: 27538856 - DOI: 10.1002/cmdc.201600327
Dorsey ER, Yvonne Chan YF, McConnell MV, Shaw SY, Trister AD, Friend SH
The Use of Smartphones for Health Research.
Acad Med. 2016;92(2):157-160 - PMID: 27119325 - DOI: 10.1097/ACM.0000000000001205
Castro MM, Kim B, Hill E, Fialho MC, Puga LC, Freitas MB, Breton S, Machado-Neves M
The expression patterns of aquaporin 9, vacuolar H(+)-ATPase, and cytokeratin 5 in the epididymis of the common vampire bat.
Histochem Cell Biol. 2016;147(1):39-48 - PMID: 27549752 - DOI: 10.1007/s00418-016-1477-9
Moss ML, Miller MA, Vujanovic N, Yoneyama T, Rasmussen FH
Fluorescent substrates for ADAM15 useful for assaying and high throughput screening.
Anal Biochem. 2016;514:42-47 - PMID: 27637923 - DOI: 10.1016/j.ab.2016.09.010
Agarwal S, Grajo JR, Fuentes-Orrego JM, Abtahi SM, Harisinghani MG, Saini S, Hahn PF
Distinguishing hemangiomas from metastases on liver MRI performed with gadoxetate disodium: Value of the extended washout sign.
Eur J Radiol. 2016;85(3):635-40 - PMID: 26860678 - DOI: 10.1016/j.ejrad.2015.12.028
Kilcoyne A, Kaplan JL, Gee MS
Inflammatory bowel disease imaging: Current practice and future directions.
World J Gastroenterol. 2016;22(3):917-32 - PMID: 26811637 - PMCID: PMC4716045 - DOI: 10.3748/wjg.v22.i3.917
Stats MA, Stone JR
Varying levels of small microcalcifications and macrophages in ATTR and AL cardiac amyloidosis: implications for utilizing nuclear medicine studies to subtype amyloidosis.
Cardiovasc Pathol. 2016;25(5):413-417 - PMID: 27469499 - DOI: 10.1016/j.carpath.2016.07.001
Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, Bruneval P, Buja LM, Butany J, d'Amati G, Fallon JT, Gallagher PJ, Gittenberger-de Groot AC, Gouveia RH, Kholova I, Kelly KL, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Stone JR, Suvarna SK, Tan CD, Thiene G, Veinot JP, van der Wal AC
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria.
Cardiovasc Pathol. 2016;25(3):247-257 - PMID: 27031798 - DOI: 10.1016/j.carpath.2016.03.002
Li Y, Stone JR
The impact of splenectomy on human coronary artery atherosclerosis and vascular macrophage distribution.
Cardiovasc Pathol. 2016;25(6):453-460 - PMID: 27614166 - DOI: 10.1016/j.carpath.2016.08.001
Ghosh B, Zhao WN, Reis SA, Patnaik D, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ
Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.
Bioorg Med Chem Lett. 2016;26(4):1265-71 - PMID: 26804233 - PMCID: PMC4753070 - DOI: 10.1016/j.bmcl.2016.01.022
Chang SY, Lo CS, Zhao XP, Liao MC, Chenier I, Bouley R, Ingelfinger JR, Chan JS, Zhang SL
Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2-HO-1 pathway in renal proximal tubular cells of transgenic mice.
J Renin Angiotensin Aldosterone Syst. 2016;17(3):ePub - PMID: 27638854 - DOI: 10.1177/1470320316668737
Hedgire SS, Kudrimoti S, Oliveira IS, Nadkarni N, McDermott S, Hahn PF, Mino-Kenudson M, Harisinghani MG
Extranodal lymphomas of abdomen and pelvis: imaging findings and differential diagnosis.
Abdom Radiol. 2016;42(4):1096-1112 - PMID: 27866240 - DOI: 10.1007/s00261-016-0964-8
Diaz-Gil D, Fintelmann FJ, Molaei S, Elmi A, Hedgire SS, Harisinghani MG
Prediction of 5-year survival in advanced-stage ovarian cancer patients based on computed tomography peritoneal carcinomatosis index.
Abdom Radiol. 2016;41(11):2196-2202 - PMID: 27338731 - DOI: 10.1007/s00261-016-0817-5
Hassanzadeh E, Glazer DI, Dunne RM, Fennessy FM, Harisinghani MG, Tempany CM
Prostate imaging reporting and data system version 2 (PI-RADS v2): a pictorial review.
Abdom Radiol. 2016;42(1):278-289 - PMID: 27522352 - PMCID: PMC5247306 - DOI: 10.1007/s00261-016-0871-z
Kilcoyne A, Price MC, McDermott S, Harisinghani MG
Imaging on nodal staging of prostate cancer.
Future Oncol. 2016;13(6):551-565 - PMID: 27785926 - DOI: 10.2217/fon-2016-0216
Pinciroli R, Mietto C, Piriyapatsom A, Chenelle CT, Thomas JG, Pirrone M, Bry L, Wojtkiewicz GR, Nahrendorf MP, Kacmarek RM, Berra L
Endotracheal Tubes Cleaned With a Novel Mechanism for Secretion Removal: A Randomized Controlled Clinical Study.
Respir Care. 2016;61(11):1431-1439 - PMID: 27460104 - DOI: 10.4187/respcare.04363
Zhu H, Alt C, Webb RH, Melki S, Kochevar IE
Corneal Crosslinking With Rose Bengal and Green Light: Efficacy and Safety Evaluation.
Cornea. 2016;35(9):1234-41 - PMID: 27362877 - DOI: 10.1097/ICO.0000000000000916
McCormack CA, Lo Gullo R, Kalra MK, Louissaint A, Stone JR
Reliability of body size measurements obtained at autopsy: impact on the pathologic assessment of the heart.
Forensic Sci Med Pathol. 2016;12(2):139-45 - PMID: 27020890 - DOI: 10.1007/s12024-016-9773-1
Ryu WS, Schellingerhout D, Jeong SW, Nahrendorf M, Kim DE
Association between Serum Lipid Profiles and Early Neurological Deterioration in Acute Ischemic Stroke.
J Stroke Cerebrovasc Dis. 2016;25(8):2024-30 - PMID: 27256172 - DOI: 10.1016/j.jstrokecerebrovasdis.2016.05.009
Wang Z, Cho YS, Soeda T, Minami Y, Xing L, Jia H, Aguirre A, Vergallo R, Lee H, Fujimoto JG, Yu B, Jang IK
Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study.
Coron Artery Dis. 2016;27(5):350-6 - PMID: 27105047 - PMCID: PMC4912393 - DOI: 10.1097/MCA.0000000000000370
Perugino CA, Wallace ZS, Meyersohn N, Oliveira G, Stone JR, Stone JH
Large vessel involvement by IgG4-related disease.
Medicine (Baltimore). 2016;95(28):e3344 - PMID: 27428181 - PMCID: PMC4956774 - DOI: 10.1097/MD.0000000000003344
Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE
Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries.
ACS Comb Sci. 2016;18(6):271-8 - PMID: 27124678 - PMCID: PMC5321554 - DOI: 10.1021/acscombsci.5b00180
Im H, Lee H, Castro CM
Challenges influencing next generation technologies for precision medicine.
Expert Rev Precis Med Drug Dev. 2016;1(2):121-123 - PMID: 28008420 - PMCID: PMC5166706 - DOI: 10.1080/23808993.2016.1165073
Swirski FK, Nahrendorf M, Libby P
Mechanisms of Myeloid Cell Modulation of Atherosclerosis.
Microbiol Spectr. 2016;4(4):ePub - PMID: 27726819 - DOI: 10.1128/microbiolspec.MCHD-0026-2015
Sager HB, Nahrendorf M
Inflammation: a trigger for acute coronary syndrome.
Q J Nucl Med Mol Imaging. 2016;60(3):185-193 - PMID: 27273431
Park KS*, Huang CH*, Lee K, Yoo YE, Castro CM, Weissleder R, Lee H
Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system
Sci Adv. 2016;2(5):e1600300 - PMID: 28861468 - PMCID: PMC5565941 - DOI: 10.1126/sciadv.1600300
Clardy SM, Kohler RH, Vinegoni C, Iwamoto Y, Keliher EJ, Weissleder R
Two-photon imaging of pancreatic beta cells in real time in vivo
Technology. 2016;4(2):130-134
Kim J, Park JE, Nahrendorf M, Kim DE
Direct Thrombus Imaging in Stroke.
J Stroke. 2016;18(3):286-296 - PMID: 27733029 - PMCID: PMC5066439 - DOI: 10.5853/jos.2016.00906
King K, Grazette LP, Paltoo DN, McDevitt JT, Sia SK, Barrett PM, Apple FS, Gurbel PA, Weissleder R, Leeds H, Iturriaga EJ, Rao A, Adhikari B, Desvigne-Nickens P, Galis ZS, Libby P
Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group.
JACC Basic Transl Sci. 2016;1(1-2):73-86 - PMID: 26977455 - PMCID: PMC4787294 - DOI: 10.1016/j.jacbts.2016.01.008
Lee H, Shin TH, Cheon J, Weissleder R
Recent Developments in Magnetic Diagnostic Systems
Chem Rev. 2015;115(19):10690-724 - PMID: 26258867 - PMCID: PMC5791529 - DOI: 10.1021/cr500698d
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE
Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Nature. 2015;529(7584):110-4 - PMID: 26700815 - PMCID: PMC4831574 - DOI: 10.1038/nature16490
Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M
Integrative analysis of 111 reference human epigenomes.
Nature. 2015;518(7539):317-30 - PMID: 25693563 - PMCID: PMC4530010 - DOI: 10.1038/nature14248
Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.
Nat Biotechnol. 2015;33(11):1165-72 - PMID: 26458175 - PMCID: PMC4636926 - DOI: 10.1038/nbt.3383
Garris CS, Pittet MJ
ER Stress in Dendritic Cells Promotes Cancer.
Cell. 2015;161(7):1492-3 - PMID: 26091029 - DOI: 10.1016/j.cell.2015.06.006
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
Cell. 2015;160(6):1246-60 - PMID: 25748654 - PMCID: PMC4380877 - DOI: 10.1016/j.cell.2015.02.038
Liu J, Lee J, Salazar Hernandez MA, Mazitschek R, Ozcan U
Treatment of obesity with celastrol.
Cell. 2015;161(5):999-1011 - PMID: 26000480 - PMCID: PMC4768733 - DOI: 10.1016/j.cell.2015.05.011
Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK
Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.
Science. 2015;347(6227):1260-1265 - PMID: 25766237 - PMCID: PMC4376966 - DOI: 10.1126/science.aaa4268
Nahrendorf M, Swirski FK
Neutrophil-macrophage communication in inflammation and atherosclerosis.
Science. 2015;349(6245):237-8 - PMID: 26185231 - DOI: 10.1126/science.aac7801
Langer R, Weissleder R
Nanotechnology.
JAMA. 2015;313(2):135-136 - PMID: 25585320 - DOI: 10.1001/jama.2014.16315
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
Nat Immunol. 2015;17(2):159-168 - PMID: 26642357 - DOI: 10.1038/ni.3343
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Cell Stem Cell. 2015;16 (5):477-487 - PMID: 25957903 - PMCID: PMC4426344 - DOI: 10.1016/j.stem.2015.04.008
Pfirschke C, Garris C, Pittet MJ
Common TLR5 Mutations Control Cancer Progression.
Cancer Cell. 2015;27(1):1-3 - PMID: 25584886 - DOI: 10.1016/j.ccell.2014.12.008
Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB*
Single-cell magnetic imaging using a quantum diamond microscope.
Nat Methods. 2015;12(8):736-738 - PMID: 26098019 - PMCID: PMC4521973 - DOI: 10.1038/nmeth.3449
Kong L, Tang J, Little JP, Yu Y, Lämmermann T, Lin CP, Germain RN, Cui M
Continuous volumetric imaging via an optical phase-locked ultrasound lens.
Nat Methods. 2015;12(8):759-762 - PMID: 26167641 - PMCID: PMC4551496 - DOI: 10.1038/nmeth.3476
Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R*, Danuser G*, Mitchison TJ*
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy
Nat Methods. 2015;12(6):577-585 - PMID: 25867850 - PMCID: PMC4579269 - DOI: 10.1038/nmeth.3363
Dai N, Zhao L, Wrighting D, Krämer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins.
Cell Metab. 2015;21(4):609-21 - PMID: 25863250 - PMCID: PMC4663978 - DOI: 10.1016/j.cmet.2015.03.006
Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamal N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R
Predicting therapeutic nano-medicine efficacy using a companion MR imaging nanoparticle.
Sci Transl Med. 2015;7:314 - PMID: 26582898 - PMCID: PMC5462466 - DOI: 10.1126/scitranslmed.aac6522
Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Sci Transl Med. 2015;7(288):288ra77 - PMID: 25995223 - PMCID: PMC4675670 - DOI: 10.1126/scitranslmed.aaa3575
Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA
Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus"
Circulation. 2015;131(24):e531-2 - PMID: 26078375 - DOI: 10.1161/CIRCULATIONAHA.115.014802
Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M
Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Circulation. 2015;132(20):1880-90 - PMID: 26358260 - PMCID: PMC4651795 - DOI: 10.1161/CIRCULATIONAHA.115.016160
Nahrendorf M, Swirski FK
Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction
Eur Heart J. 2015;37(11):868-72 - PMID: 26351395 - PMCID: PMC4789592 - DOI: 10.1093/eurheartj/ehv453
Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA
Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo.
Eur Heart J. 2015;38(6):447-455 - PMID: 26685129 - DOI: 10.1093/eurheartj/ehv677
Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M
Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
J Exp Med. 2015;212(4):497-512 - PMID: 25800955 - PMCID: PMC4387283 - DOI: 10.1084/jem.20141642
Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA
Imaging Systemic Inflammatory Networks in Ischemic Heart Disease.
J Am Coll Cardiol. 2015;65(15):1583-1591 - PMID: 25881940 - PMCID: PMC4401833 - DOI: 10.1016/j.jacc.2015.02.034
Nair AV, Keliher EJ, Core AB, Brown D, Weissleder R
Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo.
ACS Nano. 2015;9(4):3641-53 - PMID: 25790730 - PMCID: PMC4414893 - DOI: 10.1021/acsnano.5b00428
Lee K, Shao H, Weissleder R, Lee H
Acoustic Purification of Extracellular Microvesicles.
ACS Nano. 2015;9(3):2321-7 - PMID: 25672598 - PMCID: PMC4373978 - DOI: 10.1021/nn506538f
Nahrendorf M, Swirski FK
Lifestyle Effects on Hematopoiesis and Atherosclerosis.
Circ Res. 2015;116(5):884-894 - PMID: 25722442 - PMCID: PMC4347940 - DOI: 10.1161/CIRCRESAHA.116.303550
Courties G, Herisson F, Sager H, Heidt T, Ye Y, Ying W, Sun Y, Severe N, Dutta P, Scharff J, Scadden D, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M
Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells.
Circ Res. 2015;116(3):407-17 - PMID: 25362208 - PMCID: PMC4312511 - DOI: 10.1161/CIRCRESAHA.116.305207 - Cover
Konishi M, Erdem SS, Weissleder R, Lichtman AH, McCarthy J, Libby P
Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis.
Circ Res. 2015;117(6):502-12 - PMID: 26199323 - PMCID: PMC4553143 - DOI: 10.1161/CIRCRESAHA.115.306364
Ye YX, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz GR, Iwamoto Y, Tang J, Perez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, Weissleder R, Tawakol A, Dubey S, Belanger AP, Di Carli MF, Swirski FK, Kjær A, Mulder W, Nahrendorf M
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circ Res. 2015;117(10):835-45 - PMID: 26394773 - PMCID: PMC4619168 - DOI: 10.1161/CIRCRESAHA.115.307024 - Cover
Ryan RJ, Drier Y, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE
Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.
Cancer Discov. 2015;5(10):1058-71 - PMID: 26229090 - PMCID: PMC4592453 - DOI: 10.1158/2159-8290.CD-15-0370
Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H*, Weissleder R*
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Nat Commun. 2015;6:6999 - PMID: 25959588 - PMCID: PMC4430127 - DOI: 10.1038/ncomms7999
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW
ADAM8 as a drug target in pancreatic cancer.
Nat Commun. 2015;6:6175 - PMID: 25629724 - PMCID: PMC5014123 - DOI: 10.1038/ncomms7175
Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.
Nat Commun. 2015;6:7029 - PMID: 25967391 - PMCID: PMC4435621 - DOI: 10.1038/ncomms8029
Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.
Nat Commun. 2015;6:8692 - PMID: 26503691 - PMCID: PMC4711745 - DOI: 10.1038/ncomms9692
Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M
Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.
Nat Commun. 2015;6:8803 - PMID: 26541940 - PMCID: PMC4638135 - DOI: 10.1038/ncomms9803
Di Caprio G, Stokes C, Higgins JM, Schonbrun E
Single-cell measurement of red blood cell oxygen affinity.
Proc Natl Acad Sci U S A. 2015;112(32):9984-9 - PMID: 26216973 - PMCID: PMC4538663 - DOI: 10.1073/pnas.1509252112
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK
AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Proc Natl Acad Sci U S A. 2015;112(32):E4418-27 - PMID: 26216943 - PMCID: PMC4538667 - DOI: 10.1073/pnas.1510604112
Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C
Population dynamics of islet-infiltrating cells in autoimmune diabetes.
Proc Natl Acad Sci U S A. 2015;112(5):1511-6 - PMID: 25605891 - PMCID: PMC4321317 - DOI: 10.1073/pnas.1423769112
Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL
Noninvasive imaging of immune responses.
Proc Natl Acad Sci U S A. 2015;112(19):6146-51 - PMID: 25902531 - PMCID: PMC4434737 - DOI: 10.1073/pnas.1502609112
Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H*
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone
Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451 - DOI: 10.1073/pnas.1501815112
Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C Mathis D, Weissleder R
Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
Proc Natl Acad Sci U S A. 2015;112(7):2139-44 - PMID: 25650428 - PMCID: PMC4343112 - DOI: 10.1073/pnas.1424993112
Weissleder R, Nahrendorf M
Advancing biomedical imaging
Proc Natl Acad Sci U S A. 2015;112(47):14424-8 - PMID: 26598657 - PMCID: PMC4664297 - DOI: 10.1073/pnas.1508524112
Naxerova K, Elledge SJ
Taking the brakes off telomerase.
eLife. 2015;4:ePub - PMID: 26194808 - PMCID: PMC4507575 - DOI: 10.7554/eLife.09519
Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
eLife. 2015;4:ePub - PMID: 25998054 - PMCID: PMC4441007 - DOI: 10.7554/eLife.05920
Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression.
Blood. 2015;126(16):1930-9 - PMID: 26320100 - PMCID: PMC4608240 - DOI: 10.1182/blood-2015-06-649087
Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R
On chip analysis of CNS lymphoma in cerebrospinal fluid.
Theranostics. 2015;5(8):796-804 - PMID: 26000053 - PMCID: PMC4440438 - DOI: 10.7150/thno.11220
Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA
Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735 - DOI: 10.7150/thno.12494
Kim JY, Ryu JH, Schellingerhout D, Sun IC, Lee SK, Jeon S, Kim J, Kwon IC, Nahrendorf M, Ahn CH, Kim K, Kim DE
Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.
Theranostics. 2015;5(10):1098-114 - PMID: 26199648 - PMCID: PMC4508499 - DOI: 10.7150/thno.11679
Tesfay L, Clausen KA, Kim JW, Hedge P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV
Hepcidin regulation in prostate and its disruption in prostate cancer.
Cancer Res. 2015;75(11):2254-63 - PMID: 25858146 - PMCID: PMC4454355 - DOI: 10.1158/0008-5472.CAN-14-2465
Vinegoni C, Aguirre AD, Lee S, Weissleder R
Imaging the beating heart in the mouse using intravital microscopy techniques.
Nat Protoc. 2015;10(11):1802-1819 - PMID: 26492138 - PMCID: PMC5380003 - DOI: 10.1038/nprot.2015.119
David V, Martin A, Isakova T, Spaulding C, Qi L, Ramirez V, Zumbrennen-Bullough KB, Sun CC, Lin HY, Babitt JL, Wolf M
Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production.
Kidney Int. 2015;89(1):135-46 - PMID: 26535997 - PMCID: PMC4854810 - DOI: 10.1038/ki.2015.290
Koo H, Choi M, Kim E, Hahn SK, Weissleder R, Yun SH
Bioorthogonal Click Chemistry-Based Synthetic Cell Glue.
Small. 2015;11(48):6458-66 - PMID: 26768353 - PMCID: PMC5556392 - DOI: 10.1002/smll.201502972 - Cover
Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H
Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease.
Hum Mol Genet. 2015;24(21):6254-63 - PMID: 26310624 - PMCID: PMC4599680 - DOI: 10.1093/hmg/ddv348
Pulli B, Ali M, Iwamoto Y, Zeller MW, Schob S, Linnoila JJ, Chen JW
Myeloperoxidase - Hepatocyte - Stellate Cell Crosstalk Promotes Hepatocyte Injury and Fibrosis in Experimental NASH.
Antioxid Redox Signal. 2015;23(16):1255-1269 - PMID: 26058518 - PMCID: PMC4677570 - DOI: 10.1089/ars.2014.6108
Desai RM, Koshy ST, Hilderbrand SA, Mooney DJ, Joshi NS
Versatile click alginate hydrogels crosslinked via tetrazine-norbornene chemistry.
Biomaterials . 2015;50:30-7 - PMID: 25736493 - DOI: 10.1016/j.biomaterials.2015.01.048
Levy O, Mortensen LJ, Boquet G, Tong Z, Perrault C, Benhamou B, Zhang J, Stratton T, Han E, Safaee H, Musabeyezu J, Yang Z, Multon MC, Rothblatt J, Deleuze JF, Lin CP, Karp JM
A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells.
Cell Rep. 2015;10(8):1261-1268 - PMID: 25732817 - PMCID: PMC4361231 - DOI: 10.1016/j.celrep.2015.01.057
He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK
Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.
Circ Heart Fail. 2015;8(5):980-7 - PMID: 26232205 - PMCID: PMC4568849 - DOI: 10.1161/CIRCHEARTFAILURE.115.002334
Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJ, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J
Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling.
JACC Cardiovasc Interv. 2015;8(2):355-63 - PMID: 25596792 - PMCID: PMC5645299 - DOI: 10.1016/j.jcin.2014.09.016
Tong T, Yang Z, Chen JW, Zhu J, Yao Z
Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma.
Oncotarget. 2015;6(31):32257-32265 - PMID: 26337080 - PMCID: PMC4741675 - DOI: 10.18632/oncotarget.4899
Nahrendorf M, Dutta P
Targeting splenic hematopoietic stem cells in cardiovascular disease.
Oncotarget. 2015;6(24):19918-9 - PMID: 26343366 - PMCID: PMC4652955 - DOI: 10.18632/oncotarget.4918
Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW
Myeloperoxidase Nuclear Imaging for Epileptogenesis.
Radiology. 2015;:141922 - PMID: 26397127 - PMCID: PMC4770943 - DOI: 10.1148/radiol.2015141922
Dutta P, Nahrendorf M
Monocytes in Myocardial Infarction.
Arterioscler Thromb Vasc Biol. 2015;35(5):1066-70 - PMID: 25792449 - PMCID: PMC4409536 - DOI: 10.1161/ATVBAHA.114.304652
Libby P, King K
Biomarkers: A Challenging Conundrum in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2015;35(12):2491-5 - PMID: 26543097 - DOI: 10.1161/ATVBAHA.115.305233
Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D
Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.
Crit Care Med. 2015;44(5):e241-52 - PMID: 26509319 - PMCID: PMC4833510 - DOI: 10.1097/CCM.0000000000001397
Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS,
Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study.
Am J Transplant. 2015;16(1):121-36 - PMID: 26260101 - PMCID: PMC4948061 - DOI: 10.1111/ajt.13422
Siddiquee Z, Smith RN, Stone JR
An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis.
Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884 - DOI: 10.1038/modpathol.2015.105
Nahrendorf M, Swirski FK
PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction.
JACC Cardiovasc Imaging. 2015;8(12):1427-9 - PMID: 26699111 - DOI: 10.1016/j.jcmg.2015.10.004
Gonçalves I, den Ruijter H, Nahrendorf M, Pasterkamp G
Detecting the vulnerable plaque in patients.
J Intern Med. 2015;278(5):520-30 - PMID: 26306911 - DOI: 10.1111/joim.12414
Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH
Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.
Lab Chip. 2015;15(4):1153-9 - PMID: 25553996 - DOI: 10.1039/c4lc01162g
Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R
Advances in measuring single-cell pharmacokinetics and pharmacology in vivo.
Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932 - DOI: 10.1016/j.drudis.2015.05.011
Hong S, Carlson J, Lee H, Weissleder R
Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking.
Adv Healthc Mater. 2015;5(4):421-426 - PMID: 26688173 - PMCID: PMC4811597 - DOI: 10.1002/adhm.201500780
Park KS, Charles RC, Ryan ET, Weissleder R*, Lee H*
Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease
Chem Eur J. 2015;21(46):16359-63 - PMID: 26420633 - PMCID: PMC4816641 - DOI: 10.1002/chem.201502934
Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA
Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging.
Sci Rep. 2015;5:17220 - PMID: 26610702 - PMCID: PMC4661695 - DOI: 10.1038/srep17220
Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA
Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.
Sci Rep. 2015;5:15150 - PMID: 26477568 - PMCID: PMC4609913 - DOI: 10.1038/srep15150
Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R
Single cell resolution in vivo imaging of DNA damage following PARP inhibition
Sci Rep. 2015;5:10129 - PMID: 25984718 - PMCID: PMC4434991 - DOI: 10.1038/srep10129
Clardy SM, James F. Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R
Rapid, high efficiency isolation of pancreatic ß-cells
Sci Rep. 2015;5:13681 - PMID: 26330153 - PMCID: PMC4557033 - DOI: 10.1038/srep13681
Merkulova M, Păunescu TG, Azroyan A, Marshansky V, Breton S, Brown D
Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.
Sci Rep. 2015;5:14827 - PMID: 26442671 - PMCID: PMC4595830 - DOI: 10.1038/srep14827
Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, Hanna RN, Wu R, Swirski FK, Geissmann F, Hedrick CC
The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus.
Sci Rep. 2015;5:10055 - PMID: 26091486 - PMCID: PMC4473761 - DOI: 10.1038/srep10055
Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M
Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation.
J Immunol. 2015;195(3):1282-92 - PMID: 26085679 - PMCID: PMC4506852 - DOI: 10.4049/jimmunol.1401511
Iaconelli J, Huang JH, Berkovitch SS, Chattopadhyay S, Mazitschek R, Schreiber SL, Haggarty SJ, Karmacharya R
HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells.
ACS Chem Biol. 2015;10(3):883-90 - PMID: 25546293 - PMCID: PMC4372110 - DOI: 10.1021/cb500838r
Hulsmans M, Sam F, Nahrendorf M
Monocyte and macrophage contributions to cardiac remodeling.
J Mol Cell Cardiol. 2015;93:149-55 - PMID: 26593722 - PMCID: PMC4846552 - DOI: 10.1016/j.yjmcc.2015.11.015
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I
Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort.
Inflamm Bowel Dis. 2015;22(1):151-158 - PMID: 26332313 - PMCID: PMC4772891 - DOI: 10.1097/MIB.0000000000000580
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ
Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Inflamm Bowel Dis. 2015;21(11):2507-2514 - PMID: 26241000 - PMCID: PMC4615315 - DOI: 10.1097/MIB.0000000000000524
Guan Y, Meurer M, Raghavan S, Rebane A, Lindquist JR, Santos S, Kats I, Davidson MW, Mazitschek R, Hughes TE, Drobizhev M, Knop M, Shah JV
Live Cell Multi-Photon Fluorescence Correlation Spectroscopy with an Improved Large Stokes Shift Fluorescent Protein.
Mol Biol Cell. 2015;26(11):2054-66 - PMID: 25877871 - PMCID: PMC4472016 - DOI: 10.1091/mbc.E14-10-1473
Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R
Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies.
Bioconjug Chem. 2015;27(1):257-63 - PMID: 26684717 - PMCID: PMC4858350 - DOI: 10.1021/acs.bioconjchem.5b00630
Kim E, Yang K, Kohler R, Dubach JM, Mikula H, Weissleder R
Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression.
Bioconjug Chem. 2015;26(8):1513-1518 - PMID: 26017814 - PMCID: PMC4772718 - DOI: 10.1021/acs.bioconjchem.5b00152
Park YI, Im H, Weissleder R, Lee H
Nanostar clustering improves the sensitivity of plasmonic assays.
Bioconjug Chem. 2015;26(8):1470-1474 - PMID: 26102604 - PMCID: PMC5292976 - DOI: 10.1021/acs.bioconjchem.5b00343
Pang Y, Tsigkou O, Spencer JA, Lin CP, Neville C, Grottkau B
Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing.
Tissue Eng Part C Methods. 2015;21(10):1025-1031 - PMID: 25962617 - PMCID: PMC4593976 - DOI: 10.1089/ten.TEC.2015.0091
Im H, Shao H, Weissleder R, Castro CM, Lee H
Nano-plasmonic exosome diagnostics.
Expert Rev Mol Diagn. 2015;:1-9 - PMID: 25936957 - PMCID: PMC4675626 - DOI: 10.1586/14737159.2015.1041378
Whitley MJ, Weissleder R, Kirsch DG
Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer.
Semin Radiat Oncol. 2015;25(4):313-21 - PMID: 26384279 - PMCID: PMC4575408 - DOI: 10.1016/j.semradonc.2015.05.005
Kim B, Breton S
The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis.
Biol Reprod. 2015;94(1):22 - PMID: 26658708 - PMCID: PMC4809559 - DOI: 10.1095/biolreprod.115.134965
Patel H, Patel H, Higgins JM
Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease.
Am J Hematol. 2015;90(5):422-8 - PMID: 25691355 - PMCID: PMC4717489 - DOI: 10.1002/ajh.23982
Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T
Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
J Am Med Inform Assoc. 2015;22(5):993-1000 - PMID: 25929596 - PMCID: PMC4986664 - DOI: 10.1093/jamia/ocv034
Azroyan A, Cortez-Retamozo V, Bouley R, Liberman R, Ruan YC, Kiselev E, Jacobson KA, Pittet MJ, Brown D, Breton S
Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor.
PLoS ONE. 2015;10(3):e0121419 - PMID: 25799465 - PMCID: PMC4370445 - DOI: 10.1371/journal.pone.0121419
Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M
Engineered Trehalose Permeable to Mammalian Cells.
PLoS ONE. 2015;10(6):e0130323 - PMID: 26115179 - PMCID: PMC4482662 - DOI: 10.1371/journal.pone.0130323
Chung HJ, Pellegrini KL, Chung J, Wanigasuriya K, Jayawardene I, Lee K, Lee H, Vaidya VS, Weissleder R
Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury.
PLoS ONE. 2015;10(7):e0133417 - PMID: 26186708 - PMCID: PMC4506142 - DOI: 10.1371/journal.pone.0133417
Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.
PLoS ONE. 2015;10(8):e0136651 - PMID: 26301417 - PMCID: PMC4547801 - DOI: 10.1371/journal.pone.0136651
Rotem A, Ram O, Shoresh N, Sperling RA, Schnall-Levin M, Zhang H, Basu A, Bernstein BE, Weitz DA
High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics.
PLoS ONE. 2015;10(5):e0116328 - PMID: 26000628 - PMCID: PMC4441486 - DOI: 10.1371/journal.pone.0116328
Rice WL, Li W, Mamuya F, McKee M, Păunescu TG, Lu HA
Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture.
PLoS ONE. 2015;10(7):e0131719 - PMID: 26147297 - PMCID: PMC4493001 - DOI: 10.1371/journal.pone.0131719
Kessinger CW, Kim JW, Henke PK, Thompson B, McCarthy JR, Hara T, Sillesen M, Margey RJ, Libby P, Weissleder R, Lin CP, Jaffer FA
Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring.
PLoS ONE. 2015;10(2):e0116621 - PMID: 25680183 - PMCID: PMC4334538 - DOI: 10.1371/journal.pone.0116621
Da Silva N, Barton CR
Macrophages and dendritic cells in the post-testicular environment.
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Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ
Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells.
Am J Physiol Renal Physiol. 2015;:ajprenal.00152.2015 - PMID: 26290367 - PMCID: PMC4609919 - DOI: 10.1152/ajprenal.00152.2015
Herak-Kramberger CM, Breljak D, Ljubojević M, Matokanovic M, Lovric M, Rogic D, Brzica H, Vrhovac I, Karaica D, Micek V, Ivkovic Dupor J, Brown D, Sabolic I
Sex-dependent expression of water channel AQP1 along the rat nephron.
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Heng E, Stone JR, Kim JB, Lee H, MacGillivray TE, Sundt TM
Comparative Histology of Aortic Dilatation Associated With Bileaflet Versus Trileaflet Aortic Valves.
Ann Thorac Surg. 2015;100(6):2095-2101 - PMID: 26338050 - DOI: 10.1016/j.athoracsur.2015.05.105
Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.
Eur J Med Chem. 2015;102:320-333 - PMID: 26295174 - DOI: 10.1016/j.ejmech.2015.07.047
Chousterman BG, Swirski FK
Innate Response Activator B cells: origins and functions.
Int Immunol. 2015;27(10):537-41 - PMID: 25957266 - PMCID: PMC4693688 - DOI: 10.1093/intimm/dxv028
Ullal AV, Weissleder R
Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells.
Methods Mol Biol. 2015;1346:47-54 - PMID: 26542714 - DOI: 10.1007/978-1-4939-2987-0_4
Brettman AD, Tan PH, Tran K, Shaw SY
Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles.
Methods Mol Biol. 2015;1263:15-27 - PMID: 25618333 - PMCID: PMC4357233 - DOI: 10.1007/978-1-4939-2269-7_2
Davis RW, Eggleston H, Johnson F, Nahrendorf M, Bock PE, Peterson T, Panizzi P
In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model.
Mol Imaging Biol. 2015;17(6):793-801 - PMID: 25921659 - PMCID: PMC4807872 - DOI: 10.1007/s11307-015-0856-2
Carlucci G, Carney B, Brand C, Kossatz S, Irwin CP, Carlin SD, Keliher EJ, Weber W, Reiner T
Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma.
Mol Imaging Biol. 2015;17(6):848-55 - PMID: 25895168 - PMCID: PMC4609241 - DOI: 10.1007/s11307-015-0858-0
Kim B, Breton S
Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis.
Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361
Joseph P, Ishai A, MacNabb M, Abdelbaky A, Lavender ZR, Ruskin J, Nahrendorf M, Tawakol A
Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation.
Int J Cardiovasc Imaging. 2015;32(1):113-119 - PMID: 26411879 - PMCID: PMC4730873 - DOI: 10.1007/s10554-015-0766-z
Corey KE, Kartoun U, Zheng H, Shaw SY
Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.
Dig Dis Sci. 2015;61(3):913-9 - PMID: 26537487 - PMCID: PMC4761309 - DOI: 10.1007/s10620-015-3952-x
Da Silva N, Smith TB
Exploring the role of mononuclear phagocytes in the epididymis.
Asian J Androl. 2015;17(4):591-6 - PMID: 25966624 - PMCID: PMC4492049 - DOI: 10.4103/1008-682X.153540
Breton S, Ruan YC, Park YJ, Kim B
Regulation of epithelial function, differentiation, and remodeling in the epididymis.
Asian J Androl. 2015;18(1):3-9 - PMID: 26585699 - PMCID: PMC4736353 - DOI: 10.4103/1008-682X.165946
Li Y, Zhao T, Liu B, Halaweish I, Mazitschek R, Duan X, Alam HB
Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model.
J Trauma Acute Care Surg. 2015;78(2):378-85 - PMID: 25757125 - PMCID: PMC4357277 - DOI: 10.1097/TA.0000000000000510
Kevin Li-Chun H, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW
Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis.
J Neuroimmunol. 2015;287:36-42 - PMID: 26439960 - PMCID: PMC4595933 - DOI: 10.1016/j.jneuroim.2015.08.006
Stone JR, Bruneval P, Angelini A, Bartoloni G, Basso C, Batoroeva L, Buja LM, Butany J, d'Amati G, Fallon JT, Gittenberger-de Groot AC, Gouveia RH, Halushka MK, Kelly KL, Kholova I, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Suvarna SK, Tan CD, Thiene G, van der Wal AC, Veinot JP
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.
Cardiovasc Pathol. 2015;24(5):267-278 - PMID: 26051917 - DOI: 10.1016/j.carpath.2015.05.001
Huck A, Pozdnyakova O, Brunner A, Higgins JM, Fathi AT, Hasserjian RP
Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia.
Leuk Res. 2015;39(10):1034-40 - PMID: 26220865 - PMCID: PMC5764101 - DOI: 10.1016/j.leukres.2015.06.012
Framme C, Walter A, Berger L, Prahs P, Alt C, Theisen-Kunde D, Kowal J, Brinkmann R
Selective Retina Therapy in Acute and Chronic-Recurrent Central Serous Chorioretinopathy.
Ophthalmologica. 2015;234(4):177-188 - PMID: 26368551 - DOI: 10.1159/000439188
Lo Gullo R, Mishra S, Lira DA, Padole A, Otrakji A, Khawaja RD, Pourjabbar S, Singh S, Shepard JO, Digumarthy SR, Kalra MK, Stone JR
Quantification of interstitial fluid on whole body CT: comparison with whole body autopsy.
Forensic Sci Med Pathol. 2015;11(4):488-496 - PMID: 26541472 - DOI: 10.1007/s12024-015-9728-y
Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY
Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys.
BMC Nephrol. 2015;16(1):119 - PMID: 26227484 - PMCID: PMC4521488 - DOI: 10.1186/s12882-015-0120-7
Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK
Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents.
Coron Artery Dis. 2015;27(1):19-28 - PMID: 26554662 - PMCID: PMC4679565 - DOI: 10.1097/MCA.0000000000000319
Liang JS, Lee SP, Pulli B, Chen JW, Kao SC, Tsang YM, Hsieh KL
Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study.
Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405 - DOI: 10.1016/j.pedneo.2015.10.003
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Acta Neuropathol Commun. 2015;3(1):22 - PMID: 25853389 - PMCID: PMC4382927 - DOI: 10.1186/s40478-015-0201-7
Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, Huang P, Fukumura D, Engelman JA, Jain RK
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment.
J Natl Cancer Inst. 2015;108(2):ePub - PMID: 26547932 - PMCID: PMC4862418 - DOI: 10.1093/jnci/djv313
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Sci Adv. 2015;1(3):ePub - PMID: 26295063 - PMCID: PMC4539616 - DOI: 10.1126/sciadv.1400223
Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H
The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.
ACS Cent Sci. 2015;1(3):142-147 - PMID: 26955657 - PMCID: PMC4778250 - DOI: 10.1021/acscentsci.5b00121
Naxerova K, Jain RK
Using tumour phylogenetics to identify the roots of metastasis in humans.
Nat Rev Clin Oncol. 2015;12(5):258-72 - PMID: 25601447 - DOI: 10.1038/nrclinonc.2014.238
Vinegoni C, Lee S, Aguirre AD, Weissleder R
New techniques for motion-artifact-free in vivo cardiac microscopy.
Front Physiol. 2015;6:147 - PMID: 26029116 - PMCID: PMC4428079 - DOI: 10.3389/fphys.2015.00147
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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.
New Engl J Med. 2014;371(26):2488-2498 - PMID: 25426837 - PMCID: PMC4306669 - DOI: 10.1056/NEJMoa1408617
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Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure.
New Engl J Med. 2014;370(7):651-60 - PMID: 24521112 - DOI: 10.1056/NEJMcpc1310004
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ABCB5 is a limbal stem cell gene required for corneal development and repair.
Nature. 2014;511(7509):353-7 - PMID: 25030174 - PMCID: PMC4246512 - DOI: 10.1038/nature13426
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Direct measurement of local oxygen concentration in the bone marrow of live animals.
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Genetic and epigenetic fine mapping of causal autoimmune disease variants.
Nature. 2014;518(7539):337-43 - PMID: 25363779 - PMCID: PMC4336207 - DOI: 10.1038/nature13835
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Dissecting neural differentiation regulatory networks through epigenetic footprinting.
Nature. 2014;518(7539):355-9 - PMID: 25533951 - PMCID: PMC4336237 - DOI: 10.1038/nature13990
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Imaging macrophages with nanoparticles.
Nat Mater. 2014;13(2):125-38 - PMID: 24452356 - DOI: 10.1038/nmat3780 - Cover
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Nat Genet. 2014;46(4):364-70 - PMID: 24584072 - PMCID: PMC4086945 - DOI: 10.1038/ng.2913
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Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947 - DOI: 10.1038/nbt.2886
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Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
Cell. 2014;158(5):1110-22 - PMID: 25171411 - PMCID: PMC4149753 - DOI: 10.1016/j.cell.2014.07.013
Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells.
Cell. 2014;157(3):580-94 - PMID: 24726434 - PMCID: PMC4004670 - DOI: 10.1016/j.cell.2014.02.030
Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AK, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Panigrahy D, Schroeder A, Kotelianski V, Langer R, Anderson DG
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
Nat Nanotechnol. 2014;9(8):648-55 - PMID: 24813696 - PMCID: PMC4207430 - DOI: 10.1038/nnano.2014.84
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.
Science. 2014;344(6190):1396-401 - PMID: 24925914 - PMCID: PMC4123637 - DOI: 10.1126/science.1254257
Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL
Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors.
Science. 2014;344(6184):630-4 - PMID: 24797482 - PMCID: PMC4123747 - DOI: 10.1126/science.1251141
Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M
Chronic variable stress activates hematopoietic stem cells
Nature Med. 2014;20(7):754-758 - PMID: 24952646 - PMCID: PMC4087061 - DOI: 10.1038/nm.3589
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN
EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma.
Cancer Cell. 2014;26(5):668-81 - PMID: 25453903 - PMCID: PMC4492343 - DOI: 10.1016/j.ccell.2014.10.004
Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R
Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin
Sci Transl Med. 2014;6 (261):261ra152 - PMID: 25378644 - PMCID: PMC4330962 - DOI: 10.1126/scitranslmed.3009318
Kobzik L, Swirski FK
MARCOing Monocytes for Elimination.
Sci Transl Med. 2014;6(219):219fs4 - PMID: 24431109 - PMCID: PMC4374341 - DOI: 10.1126/scitranslmed.3008448
Mulder WJ, Jaffer FA, Fayad ZA, Nahrendorf M
Imaging and Nanomedicine in Inflammatory Atherosclerosis.
Sci Transl Med. 2014;6(239):239sr1 - PMID: 24898749 - PMCID: PMC4110972 - DOI: 10.1126/scitranslmed.3005101 - Cover
Ullal AV*, Peterson V*, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R
Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates
Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113 - PMCID: PMC4063286 - DOI: 10.1126/scitranslmed.3007361
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Nat Neurosci. 2014;17(9):1156-1163 - PMID: 25129075 - PMCID: PMC4292795 - DOI: 10.1038/nn.3786
Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity.
Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655 - DOI: 10.1161/CIRCULATIONAHA.113.006381
Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA
FDG-PET/CT Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus.
Circulation. 2014;130(13):1044-52 - PMID: 25070665 - PMCID: PMC4174982 - DOI: 10.1161/CIRCULATIONAHA.114.008902
Kroll MW, Lakkireddy DR, Stone JR, Luceri RM
TASER Electronic Control Devices and Cardiac Arrests: Coincidental or Causal?
Circulation. 2014;129(1):93-100 - PMID: 24396012 - DOI: 10.1161/CIRCULATIONAHA.113.004401
Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ
Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study.
Eur Heart J. 2014;35(42):2972-9 - PMID: 24742886 - PMCID: PMC4223610 - DOI: 10.1093/eurheartj/ehu153
Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M
Silencing of CCR2 in myocarditis.
Eur Heart J. 2014;36(23):1478-88 - PMID: 24950695 - PMCID: PMC4465633 - DOI: 10.1093/eurheartj/ehu225
Attanasio C, Nord AS, Zhu Y, Blow MJ, Biddie SC, Mendenhall EM, Dixon J, Wright CA, Hosseini R, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Afzal V, Ren B, Bernstein B, Rubin E, Visel A, Pennacchio L
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.
Genome Res. 2014;24(6):920-9 - PMID: 24752179 - PMCID: PMC4032856 - DOI: 10.1101/gr.168930.113
Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
J Exp Med. 2014;211(6):1243-56 - PMID: 24821911 - PMCID: PMC4042649 - DOI: 10.1084/jem.20131471
Taqueti VR, Nahrendorf M, Di Carli MF
Translational molecular imaging: repurposing an old technique to track cell migration into human atheroma.
J Am Coll Cardiol. 2014;64(10):1030-2 - PMID: 25190239 - DOI: 10.1016/j.jacc.2014.07.004
Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R
Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging.
Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131 - DOI: 10.1002/anie.201403890
Dutta P, Nahrendorf M
Regulation and consequences of monocytosis.
Immunol Rev. 2014;262(1):167-78 - PMID: 25319334 - PMCID: PMC4203415 - DOI: 10.1111/imr.12219
Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire C, Chen JW, Tannous BA, Breakefield XO
Dynamic Biodistribution of Extracellular Vesicles In Vivo Using a Multimodal Imaging Reporter.
ACS Nano. 2014;8(1):483-94 - PMID: 24383518 - PMCID: PMC3934350 - DOI: 10.1021/nn404945r
Heidt T, Courties G, Dutta P, Sager H, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M
Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction.
Circ Res. 2014;115(2):284-95 - PMID: 24786973 - PMCID: PMC4082439 - DOI: 10.1161/CIRCRESAHA.115.303567
Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherrer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium.
Circ Res. 2014;114(10):1611-22 - PMID: 24625784 - PMCID: PMC4017349 - DOI: 10.1161/CIRCRESAHA.114.303204
Swirski FK, Nahrendorf M
Do vascular smooth muscle cells differentiate to macrophages in atherosclerotic lesions?
Circ Res. 2014;115(7):605-6 - PMID: 25214571 - PMCID: PMC4166538 - DOI: 10.1161/CIRCRESAHA.114.304925
Nahrendorf M, Swirski FK
Fluorescent leukocytes enter plaque on the microscope stage.
Circ Res. 2014;114(5):740-1 - PMID: 24577957 - PMCID: PMC3957183 - DOI: 10.1161/CIRCRESAHA.114.303520
Nahrendorf M, Swirski FK
Regulating repair: regulatory T cells in myocardial infarction.
Circ Res. 2014;115(1):7-9 - PMID: 24951758 - PMCID: PMC4094354 - DOI: 10.1161/CIRCRESAHA.114.304295
Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF
A genomic and evolutionary approach reveals non-genetic drug resistance in malaria.
Genome Biol. 2014;15(11):511 - PMID: 25395010 - PMCID: PMC4272547 - DOI: 10.1186/PREACCEPT-1067113631444973
Eda H, Santo L, Cirstea DD, Yee AJ, Scullen TA, Nemani N, Mishima Y, Waterman PR, Arastu-Kapur S, Evans E, Singh J, Kirk CJ, Westlin WF, Raje NS
A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
Leukemia. 2014;28(9):1892-901 - PMID: 24518207 - DOI: 10.1038/leu.2014.69
Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, Yuan J, Ware C, MacLean J, Garrett-Engele PW, Kluk M, Laskey J, Haines BB, Moskaluk C, Zawel L, Fawell S, Gilliland G, Zhang T, Kremer B, Knoechel B, Bernstein BE, Pear WS, Liu XS, Aster JC, Sathyanarayanan S
Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma.
Cancer Discov. 2014;4(10):1154-67 - PMID: 25104330 - PMCID: PMC4184927 - DOI: 10.1158/2159-8290.CD-13-0830
Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R
In vivo imaging of specific drug-target binding at subcellular resolution.
Nat Commun. 2014;5:3946 - PMID: 24867710 - PMCID: PMC4362617 - DOI: 10.1038/ncomms4946
Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation.
Nat Commun. 2014;5:3065 - PMID: 24445279 - PMCID: PMC4001802 - DOI: 10.1038/ncomms4065
Lee SK, Mortensen LJ, Lin CP, Tung CH
An authentic imaging probe to track cell fate from beginning to end.
Nat Commun. 2014;5:5216 - PMID: 25323442 - PMCID: PMC4852472 - DOI: 10.1038/ncomms6216
Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B
Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.
Nat Commun. 2014;5:5662 - PMID: 25489927 - PMCID: PMC4261930 - DOI: 10.1038/ncomms6662
Aguirre AD, Vinegoni C, Sebas M, Weissleder R
Intravital imaging of cardiac function at the single-cell level.
Proc Natl Acad Sci U S A. 2014;111(31):11257-62 - PMID: 25053815 - PMCID: PMC4128110 - DOI: 10.1073/pnas.1401316111
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC
Defining functional DNA elements in the human genome.
Proc Natl Acad Sci U S A. 2014;111(17):6131-6138 - PMID: 24753594 - PMCID: PMC4035993 - DOI: 10.1073/pnas.1318948111
Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D
Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature.
Proc Natl Acad Sci U S A. 2014;111(31):11419-24 - PMID: 25049388 - PMCID: PMC4128122 - DOI: 10.1073/pnas.1410854111
Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
Proc Natl Acad Sci U S A. 2014;111(46):E4946-53 - PMID: 25369933 - PMCID: PMC4246292 - DOI: 10.1073/pnas.1407079111
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC
Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease.
Proc Natl Acad Sci U S A. 2014;111(33):E3366 - PMID: 25275169 - PMCID: PMC4143047
Naxerova K, Brachtel E, Salk JJ, Seese AM, Power K, Abbasi B, Snuderl M, Chiang S, Kasif S, Jain RK
Hypermutable DNA chronicles the evolution of human colon cancer.
Proc Natl Acad Sci U S A. 2014;111(18):E1889-98 - PMID: 24753616 - PMCID: PMC4020055 - DOI: 10.1073/pnas.1400179111
Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut.
Proc Natl Acad Sci U S A. 2014;111(18):6696-701 - PMID: 24753589 - PMCID: PMC4020091 - DOI: 10.1073/pnas.1405634111
Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D
Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
eLife. 2014;3:e04631 - PMID: 25407682 - PMCID: PMC4270084 - DOI: 10.7554/eLife.04631 - Cover
Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Del Toro R, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192 - DOI: 10.1182/blood-2014-08-593426
Babitt JL, Lin HY
BuMPing iron with modified heparins.
Blood. 2014;123(10):1440-1 - PMID: 24627550 - PMCID: PMC3945857 - DOI: 10.1182/blood-2014-01-549519
Yoon YI, Kwon YS, Cho HS, Heo SH, Park KS, Park SG, Lee SH, Hwang SI, Kim YI, Jae HJ, Ahn GJ, Cho YS, Lee H*, Lee HJ*, Yoon TJ*
Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System
Theranostics. 2014;4(11):1133-1144
Chan CT, Qi J, Smith W, Paranal R, Mazitschek R, West N, Reeves R, Chiosis G, Schreiber SL, Bradner JE, Paulmurugan R, Gambhir SS
Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase (HDAC) Inhibitors by Multimodality Molecular Imaging in Living Subjects.
Cancer Res. 2014;74(24):7475-86 - PMID: 25320008 - PMCID: PMC4315624 - DOI: 10.1158/0008-5472.CAN-14-0197
Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L
Harnessing the Intestinal Microbiome for Optimal Therapeutic Immunomodulation.
Cancer Res. 2014;74(16):4217-4221 - PMID: 25074615 - DOI: 10.1158/0008-5472.CAN-14-0987
Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L
Gut microbiome and anticancer immune response: really hot Sh*t!
Cell Death Differ. 2014;22(2):199-214 - PMID: 24832470 - PMCID: PMC4291500 - DOI: 10.1038/cdd.2014.56
Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Desphande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman JA, Bardeesy N
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer.
Clin Cancer Res. 2014;21(2):396-404 - PMID: 25348516 - PMCID: PMC4447091 - DOI: 10.1158/1078-0432.CCR-14-1591
Teo GS, Yang Z, Carman CV, Karp JM, Lin CP
Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association with Platelets and Neutrophils.
Stem Cells. 2014;33(1):265-277 - PMID: 25263183 - PMCID: PMC4270897 - DOI: 10.1002/stem.1848
Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.
Sci Signal. 2014;7(348):ra100 - PMID: 25336613 - PMCID: PMC4300109 - DOI: 10.1126/scisignal.2005262
Ghazani A, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R
Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance.
Nanomedicine. 2014;10 :661-668 - PMID: 24200523 - PMCID: PMC3966960 - DOI: 10.1016/j.nano.2013.10.008
Aranda F, Bloy N, Pesquet J, Petit B, Chaba K, Sauvat A, Kepp O, Khadra N, Enot D, Pfirschke C, Pittet M, Zitvogel L, Kroemer G, Senovilla L
Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer.
Oncogene. 2014;34(23):3053-62 - PMID: 25065595 - DOI: 10.1038/onc.2014.234
Lan YY, Londoño D, Bouley R, Rooney MS, Hacohen N
Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy.
Cell Rep. 2014;9(1):180-92 - PMID: 25284779 - PMCID: PMC4555847 - DOI: 10.1016/j.celrep.2014.08.074
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases.
Clin Gastroenterol Hepatol. 2014;12(11):1905-1910 - PMID: 24632349 - PMCID: PMC4162859 - DOI: 10.1016/j.cgh.2014.02.034
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2014;12(8):1342-1348.e1 - PMID: 24407106 - PMCID: PMC4085150 - DOI: 10.1016/j.cgh.2013.12.030
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2014;13(2):322-329.e1 - PMID: 25041865 - PMCID: PMC4297589 - DOI: 10.1016/j.cgh.2014.07.018
Castro CM, Im H, Le C, Lee H, Weissleder R, Birrer MJ
Exploring alternative ovarian cancer biomarkers using innovative nanotechnology strategies.
Cancer Metastasis Rev. 2014;34(1):75-82 - PMID: 25543192 - PMCID: PMC5474936 - DOI: 10.1007/s10555-014-9546-9
Pulli B, Bure L, Wojtkiewicz GR, Iwamoto Y, Ali M, Li D, Schob S, Li-Chun Hsieh K, Jacobs AH, Chen JW
Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model.
Radiology. 2014;:141495 - PMID: 25494298 - PMCID: PMC4455671 - DOI: 10.1148/radiol.14141495
Hilgendorf I, Swirski FK, Robbins CS
Monocyte Fate in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2014;35(2):272-9 - PMID: 25538208 - DOI: 10.1161/ATVBAHA.114.303565
Kim E, Yang KS, Giedt RJ, Weissleder R
Red Si-rhodamine drug conjugates enable imaging in GFP cells.
Chem Commun. 2014;50(34):4504-7 - PMID: 24663433 - PMCID: PMC4028821 - DOI: 10.1039/c4cc00144c
Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A
Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.
JACC Cardiovasc Imaging. 2014;8(2):121-30 - PMID: 25577441 - DOI: 10.1016/j.jcmg.2014.10.009
Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R*, Lee H*
Magnetic sensing technology for molecular analyses.
Lab Chip. 2014;14(14):2385-97 - PMID: 24887807 - PMCID: PMC4098149 - DOI: 10.1039/c4lc00314d
Frantz S, Nahrendorf M
Cardiac macrophages and their role in ischemic heart disease.
Cardiovasc Res. 2014;102(2):240-8 - PMID: 24501331 - PMCID: PMC3989449 - DOI: 10.1093/cvr/cvu025
Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway.
J Cell Sci. 2014;127(Pt 20):4396-408 - PMID: 25107366 - PMCID: PMC4197086 - DOI: 10.1242/jcs.148098 - Cover
Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R*
Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040 - DOI: 10.1002/adhm.201300672
Nahrendorf M, Swirski FK
Imaging systemic inflammation in patients with acute myocardial infarction.
Circ Cardiovasc Imaging. 2014;7(5):762-4 - PMID: 25227235 - DOI: 10.1161/CIRCIMAGING.114.002410
Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P
Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata.
Circ Cardiovasc Imaging. 2014;7(6):920-929 - PMID: 25170063 - PMCID: PMC4237630 - DOI: 10.1161/CIRCIMAGING.114.002113
Roussakis E, Spencer JA, Lin CP, Vinogradov SA
Two-Photon Antenna-Core Oxygen Probe with Enhanced Performance.
Anal Chem. 2014;86(12):5937-45 - PMID: 24848643 - PMCID: PMC4066907 - DOI: 10.1021/ac501028m
Thurber G, Reiner T, Yang K, Kohler R, Weissleder R
Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors.
Mol Cancer Ther. 2014;13(4):986-95 - PMID: 24552776 - PMCID: PMC3981972 - DOI: 10.1158/1535-7163.MCT-13-0801
Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R
Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.
Sci Rep. 2014;4:4782 - PMID: 24759210 - PMCID: PMC3998017 - DOI: 10.1038/srep04782
Lee S, Vinegoni C, Sebas M, Weissleder R
Automated motion artifact removal for intravital microscopy, without a priori information.
Sci Rep. 2014;4:4507 - PMID: 24676021 - PMCID: PMC3968488 - DOI: 10.1038/srep04507
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S
Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity.
ACS Chem Biol. 2014;9(4):1061 - PMID: 22724584 - DOI: 10.1021/cb300235m
Forghani R, Kim HJ, Wojtkiewicz GR, Bure L, Wu Y, Hayase M, Wei Y, Zheng Y, Moskowitz MA, Chen JW
Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke.
J Cereb Blood Flow Metab. 2014;35(3):485-93 - PMID: 25515211 - PMCID: PMC4348390 - DOI: 10.1038/jcbfm.2014.222
Swirski FK, Hilgendorf I, Robbins CS
From proliferation to proliferation: monocyte lineage comes full circle.
Semin Immunopathol. 2014;36(2):137-48 - PMID: 24435095 - PMCID: PMC3991755 - DOI: 10.1007/s00281-013-0409-1
Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes.
Mol Cell Biol. 2014;34(14):2773 - PMID: 24951669 - PMCID: PMC4097671
Malka R, Delgado FF, Manalis SR, Higgins JM
In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells.
PLoS Comput Biol. 2014;10(10):e1003839 - PMID: 25299941 - PMCID: PMC4191880 - DOI: 10.1371/journal.pcbi.1003839
Xu Y, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW
The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis.
J Lipid Res. 2014;56(2):266-76 - PMID: 25528754 - PMCID: PMC4306681 - DOI: 10.1194/jlr.M053017
Jun HJ, Roy J, Smith TB, Wood LB, Lane K, Woolfenden S, Punko D, Bronson RT, Haigis KM, Breton S, Charest A
ROS1 Signaling Regulates Epithelial Differentiation in the Epididymis.
Endocrinology. 2014;:en20141341 - PMID: 24971615 - PMCID: PMC4138574 - DOI: 10.1210/en.2014-1341
Zumbrennen-Bullough K, Wu Q, Core AB, Canali S, Chen W, Theurl I, Meynard D, Babitt JL
MicroRNA-130a is upregulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription.
J Biol Chem. 2014;289(34):23796-808 - PMID: 25002578 - PMCID: PMC4156078 - DOI: 10.1074/jbc.M114.577387
Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T
Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.
Hum Genet. 2014;133(11):1369-82 - PMID: 25062868 - PMCID: PMC4185241 - DOI: 10.1007/s00439-014-1466-9
Brand C, Abdel-Atti D, Zhang Y, Carlin S, Clardy SM, Keliher EJ, Weber WA, Lewis JS, Reiner T
In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent.
Bioconjug Chem. 2014;25(7):1323-30 - PMID: 24856928 - PMCID: PMC4215873 - DOI: 10.1021/bc500178d
Sprachman M, Laughney A, Kohler R, Weissleder R
In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor.
Bioconjug Chem. 2014;25(6):1137-42 - PMID: 24806886 - PMCID: PMC4098115 - DOI: 10.1021/bc500154c
Giedt RJ, Sprachman M, Yang K, Weissleder R
Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates.
Bioconjug Chem. 2014;25(11):2081-2085 - PMID: 25333750 - PMCID: PMC4240345 - DOI: 10.1021/bc500433k
Courtis AM, Santos SA, Guan Y, Hendricks JA, Ghosh B, Szantai-Kis DM, Reis SA, Shah JV, Mazitschek R
Monoalkoxy BODIPYs - A Fluorophore Class for Bioimaging.
Bioconjug Chem. 2014;25(6):1043-51 - PMID: 24797834 - PMCID: PMC4215867 - DOI: 10.1021/bc400575w
Marshansky V, Rubinstein JL, Grüber G
Eukaryotic V-ATPase: Novel Structural Findings and Functional Insights.
Biochim Biophys Acta. 2014;1837(6):857-879 - PMID: 24508215 - DOI: 10.1016/j.bbabio.2014.01.018
Păunescu TG, Shum WW, Huynh C, Lechner L, Goetze B, Brown D, Breton S
High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa.
Mol Hum Reprod. 2014;20(10):929-37 - PMID: 25015675 - PMCID: PMC4172170 - DOI: 10.1093/molehr/gau052
Pittet MJ, Nahrendorf M, Swirski FK
The journey from stem cell to macrophage.
Ann N Y Acad Sci. 2014;1319(1):1-18 - PMID: 24673186 - PMCID: PMC4074243 - DOI: 10.1111/nyas.12393
Michot C, Le Goff C, Mahaut C, Afenjar A, Brooks AS, Campeau PM, Destree A, Di Rocco M, Donnai D, Hennekam R, Heron D, Jacquemont S, Kannu P, Lin AE, Manouvrier-Hanu S, Mansour S, Marlin S, McGowan R, Murphy H, Raas-Rothschild A, Rio M, Simon M, Stolte-Dijkstra I, Stone JR, Sznajer Y, Tolmie J, Touraine R, van den Ende J, Van der Aa N, van Essen T, Verloes A, Munnich A, Cormier-Daire V
Myhre and LAPS syndromes: clinical and molecular review of 32 patients.
Eur J Hum Genet. 2014;22(11):1272-7 - PMID: 24424121 - PMCID: PMC4200423 - DOI: 10.1038/ejhg.2013.288
Vinegoni C, Lee S, Feruglio PF, Weissleder R
Advanced Motion Compensation Methods for Intravital Optical Microscopy.
IEEE J Sel Top Quantum Electron. 2014;20(2):ePub - PMID: 24273405 - PMCID: PMC3832946 - DOI: 10.1109/JSTQE.2013.2279314
Shum WW, Smith TB, Cortez-Retamozo V, Grigoryeva LS, Roy JW, Hill E, Pittet MJ, Breton S, Da Silva N
Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis.
Biol Reprod. 2014;90(5):90 - PMID: 24648397 - PMCID: PMC4076373 - DOI: 10.1095/biolreprod.113.116681
Kim B, Roy J, Shum WW, Da Silva N, Breton S
Role of Testicular Luminal Factors on Basal Cell Elongation and Proliferation in the Mouse Epididymis.
Biol Reprod. 2014;92(1):9 - PMID: 25411392 - PMCID: PMC4434934 - DOI: 10.1095/biolreprod.114.123943
Golub MS, Hogrefe CE, Malka R, Higgins JM
Developmental Plasticity of red blood cell homeostasis.
Am J Hematol. 2014;89(5):459-66 - PMID: 24415575 - PMCID: PMC4086753 - DOI: 10.1002/ajh.23666
Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG
Hereditary xerocytosis revisited.
Am J Hematol. 2014;89(12):1142-1146 - PMID: 25044010 - PMCID: PMC4237618 - DOI: 10.1002/ajh.23799
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J
Chemical Interrogation of the Malaria Kinome.
Chembiochem. 2014;15(13):1920-30 - PMID: 25111632 - PMCID: PMC4237307 - DOI: 10.1002/cbic.201400025 - Cover
Miranda KC, Bond DT, Levin JZ, Adiconis X, Sivachenko A, Russ C, Brown D, Nusbaum C, Russo LM
Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA.
PLoS ONE. 2014;9(5):e96094 - PMID: 24816817 - PMCID: PMC4015934 - DOI: 10.1371/journal.pone.0096094
Elman JS, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B
Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells.
PLoS ONE. 2014;9(2):e89882 - PMID: 24587097 - PMCID: PMC3931832 - DOI: 10.1371/journal.pone.0089882
Mehan WA, González RG, Buchbinder BR, Chen JW, Copen WA, Gupta R, Hirsch JA, Hunter GJ, Hunter S, Johnson JM, Kelly HR, Larvie M, Lev MH, Pomerantz SR, Rapalino O, Rincon S, Romero JM, Schaefer PW, Shah V
Optimal Brain MRI Protocol for New Neurological Complaint.
PLoS ONE. 2014;9(10):e110803 - PMID: 25343371 - PMCID: PMC4208779 - DOI: 10.1371/journal.pone.0110803
Hsieh LC, Chen JW, Wang LY, Tsang YM, Shueng PW, Liao LJ, Lo WC, Lin YC, Tseng CF, Kuo YS, Jhuang JY, Tien HJ, Juan HF, Hsieh CH
Predicting the severity and prognosis of trismus after intensity-modulated radiation therapy for oral cancer patients by magnetic resonance imaging.
PLoS ONE. 2014;9(3):e92561 - PMID: 24658376 - PMCID: PMC3962418 - DOI: 10.1371/journal.pone.0092561
Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D
High throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration.
Am J Physiol Cell Physiol. 2014;307(7):C597-605 - PMID: 24944200 - PMCID: PMC4187055 - DOI: 10.1152/ajpcell.00154.2014
Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM
Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume.
Cytometry A. 2014;85(4):332-8 - PMID: 24677669 - PMCID: PMC4717472 - DOI: 10.1002/cyto.a.22450
Chow MJ, Turcotte R, Lin CP, Zhang Y
Arterial Extracellular Matrix: A Mechanobiological Study of the Contributions and Interactions of Elastin and Collagen.
Biophys J. 2014;106(12):2684-2692 - PMID: 24940786 - PMCID: PMC4070071 - DOI: 10.1016/j.bpj.2014.05.014
Hedgire SS, Mino-Kenudson M, Elmi A, Thayer S, Fernandez-Del Castillo C, Harisinghani MG
Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation.
Int J Nanomedicine. 2014;9:1891-1896 - PMID: 24790431 - PMCID: PMC4000182 - DOI: 10.2147/IJN.S59788
Kim KM, Cambria RP, Isselbacher EM, Baker JN, LaMuraglia GM, Stone JR, MacGillivray TE
Contemporary Surgical Approaches and Outcomes in Adults With Kommerell Diverticulum.
Ann Thorac Surg. 2014;98(4):1347-1354 - PMID: 25134861 - DOI: 10.1016/j.athoracsur.2014.05.045
Alt C, Runnels JM, Mortensen LJ, Zaher W, Lin C
In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment.
Invest Ophthalmol Vis Sci. 2014;55(8):5314-5319 - PMID: 25082884 - DOI: 10.1167/iovs.14-14254
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.
J Crohns Colitis. 2014;8(9):956-63 - PMID: 24559536 - PMCID: PMC4136996 - DOI: 10.1016/j.crohns.2014.01.019
Dubach JM, Vinegoni C, Weissleder R
Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging.
Opt Lett. 2014;39(15):4482-4485 - PMID: 25078208 - PMCID: PMC4341989
Smith TB, Cortez-Retamozo V, Grigoryeva LS, Hill E, Pittet MJ, Da Silva N
Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis.
Andrology. 2014;2(5):755-62 - PMID: 25082073 - PMCID: PMC4396827 - DOI: 10.1111/j.2047-2927.2014.00251.x - Cover
Mortensen LJ, Alt C, Turcotte R, Masek M, Liu TM, Côté DC, Xu C, Intini G, Lin CP
Femtosecond laser bone ablation with a high repetition rate fiber laser source.
Biomed Opt Express. 2014;6(1):32-42 - PMID: 25657872 - PMCID: PMC4317121 - DOI: 10.1364/BOE.6.000032
Turcotte R, Alt C, Mortensen LJ, Lin CP
Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy.
Biomed Opt Express. 2014;5(10):3578-88 - PMID: 25360374 - PMCID: PMC4206326 - DOI: 10.1364/BOE.5.003578
Pulli B, Chen JW
Imaging Neuroinflammation - from Bench to Bedside.
J Clin Cell Immunol. 2014;5:ePub - PMID: 25525560 - PMCID: PMC4266918 - DOI: 10.4172/2155-9899.1000226
Wu JW, Runnels JM, Lin CP
Intravital imaging of hematopoietic stem cells in the mouse skull.
Methods Mol Biol. 2014;1185:247-65 - PMID: 25062634 - DOI: 10.1007/978-1-4939-1133-2_17
Keliher EJ, Klubnick JA Reiner T, Mazitschek R, Weissleder R
Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes.
ChemMedChem. 2014;9(7):1368-73 - PMID: 24596307 - PMCID: PMC4145401 - DOI: 10.1002/cmdc.201300506
Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R
Platinum Compounds for High-Resolution In Vivo Cancer Imaging.
ChemMedChem. 2014;9(6):1131-5 - PMID: 24504646 - PMCID: PMC4037345 - DOI: 10.1002/cmdc.201300502
Lartey FM, Ahn GO, Ali R, Rosenblum S, Miao Z, Arksey N, Shen B, Colomer MV, Rafat M, Liu H, Alejandre-Alcazar MA, Chen JW, Palmer T, Chin FT, Guzman R, Loo BW, Graves E
The Relationship Between Serial [(18) F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice.
Mol Imaging Biol. 2014;16(6):821-9 - PMID: 24865401 - PMCID: PMC4237703 - DOI: 10.1007/s11307-014-0745-0
Panizzi P, Stone JR, Nahrendorf M
Endocarditis and molecular imaging.
J Nucl Cardiol. 2014;21(3):486-95 - PMID: 24797384 - PMCID: PMC4106242 - DOI: 10.1007/s12350-014-9902-8
Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA
Computational pathology: an emerging definition.
Arch Pathol Lab Med. 2014;138(9):1133-8 - PMID: 25171694 - DOI: 10.5858/arpa.2014-0034-ED
Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Mode of Childbirth and Long-Term Outcomes in Women with Inflammatory Bowel Diseases.
Dig Dis Sci. 2014;60(2):471-7 - PMID: 25213079 - PMCID: PMC4304947 - DOI: 10.1007/s10620-014-3353-6
Wollack JW, Monson BJ, Dozier JK, Dalluge JJ, Poss K, Hilderbrand SA, Distefano MD
Site-Specific Labeling of Proteins and Peptides with Trans-cyclooctene Containing Handles Capable of Tetrazine Ligation.
Chem Biol Drug Des. 2014;84(2):140-7 - PMID: 24899362 - PMCID: PMC4107141 - DOI: 10.1111/cbdd.12303
Stone JR
Novel prognostic tissue markers in congestive heart failure.
Cardiovasc Pathol. 2014;24(2):65-70 - PMID: 25453729 - DOI: 10.1016/j.carpath.2014.07.010
Pauk M, Grgurevic L, Brkljacic J, Kufner V, Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt JL, Lin HY, Volarevic S, Vukicevic S
Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice.
Int Orthop. 2014;39(1):161-172 - PMID: 25300398 - DOI: 10.1007/s00264-014-2550-4
Zhao T, Li Y, Liu B, Halaweish I, Mazitschek R, Alam HB
Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model.
J Surg Res. 2014;190(2):647-54 - PMID: 24613069 - PMCID: PMC4267528 - DOI: 10.1016/j.jss.2014.01.056
Zhao Y, Zhou P, Liu B, Bambakidis T, Mazitschek R, Alam HB, Li Y
Protective effect of suberoylanilide hydroxamic acid against lipopolysaccharide-induced liver damage in rodents.
J Surg Res. 2014;194(2):544-550 - PMID: 25479907 - PMCID: PMC4361238 - DOI: 10.1016/j.jss.2014.10.056
Oklu R, Stone JR, Albadawi H, Watkins MT
Extracellular Traps in Lipid-Rich Lesions of Carotid Atherosclerotic Plaques: Implications for Lipoprotein Retention and Lesion Progression.
J Vasc Interv Radiol. 2014;25(4):631-4 - PMID: 24581730 - DOI: 10.1016/j.jvir.2013.12.567
Hedgire SS, Eberhardt SC, Borczuk R, McDermott S, Harisinghani MG
Interpretation and reporting multiparametric prostate MRI: a primer for residents and novices.
Abdom Imaging. 2014;39(5):1036-51 - PMID: 24566965 - DOI: 10.1007/s00261-014-0097-x
Iyer VR, Hedgire SS, Hoskote SS, Borczuk D, Harisinghani MG
Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up.
Abdom Imaging. 2014;40(6):1481-6 - PMID: 25516214 - DOI: 10.1007/s00261-014-0328-1
Winkler DA, Burden FR, Yan B, Weissleder R, Tassa C, Shaw S, Epa VC
Modelling and predicting the biological effects of nanomaterials.
SAR QSAR Environ Res. 2014;25(2):161-72 - PMID: 24625316 - DOI: 10.1080/1062936X.2013.874367
Higgins JM
Red Blood Cell Population Dynamics.
Clin Lab Med. 2014;35(1):43-57 - PMID: 25676371 - PMCID: PMC4717490 - DOI: 10.1016/j.cll.2014.10.002
Sheth RA, Bittencourt LK, Guimaraes AR
Diffusion-Weighted Imaging of the Male Pelvis.
Magn Reson Imaging Clin N Am. 2014;22(2):145-163 - PMID: 24792675 - DOI: 10.1016/j.mric.2014.01.003
Harisinghani MG
The male pelvis.
Magn Reson Imaging Clin N Am. 2014;22(2):xi - PMID: 24792681 - DOI: 10.1016/j.mric.2014.02.001
Bell DL, Stapleton CJ, Terry AR, Stone JR, Ogilvy CS
Clinical presentation and treatment considerations of a ruptured posterior spinal artery pseudoaneurysm.
J Clin Neurosci. 2014;21(7):1273-6 - PMID: 24572933 - DOI: 10.1016/j.jocn.2014.01.002
Park D, Spencer JA, Lin CP, Scadden DT
Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair.
J Vis Exp. 2014;(87):ePub - PMID: 24894331 - PMCID: PMC4206246 - DOI: 10.3791/51289
Hedgire SS, Elmi A, Kambadakone AR, Yoon S, Blake M, Harisinghani MG
MDCT imaging of Alloderm biologic mesh spacers in the abdomen and pelvis - preliminary experience.
Clin Imaging. 2014;38(3):279-82 - PMID: 24556330 - DOI: 10.1016/j.clinimag.2013.12.020
Hedgire SS, Tabatabaei S, McDermott S, Feldman A, Dahl DM, Harisinghani MG
Diversion ahead: imaging appearance of urinary diversions and reservoirs.
Clin Imaging. 2014;38(4):418-427 - PMID: 24602415 - DOI: 10.1016/j.clinimag.2014.01.017
Swirski FK
Monocyte recruitment and macrophage proliferation in atherosclerosis.
Kardiol Pol. 2014;72(4):311-4 - PMID: 24526549 - DOI: 10.5603/KP.a2014.0021
Alieva M, Ritsma L, Giedt RJ, Weissleder R, van Rheenen J
Imaging windows for long-term intravital imaging: general overview
Intravital. 2014;3:2: e29917
Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ
Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2.
Physiol Rep. 2014;2(12):ePub - PMID: 25472608 - PMCID: PMC4332208 - DOI: 10.14814/phy2.12226
Swirski FK
Inflammation and repair in the ischaemic myocardium.
Hamostaseologie. 2014;35(1):34-6 - PMID: 25375277 - DOI: 10.5482/HAMO-14-09-0045
Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS, Reiner T
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.
ChemistryOpen. 2014;3(2):48-53 - PMID: 24808990 - PMCID: PMC4000166 - DOI: 10.1002/open.201402000
Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy.
Nat Med. 2014;20(11):1301-9 - PMID: 25344738 - DOI: 10.1038/nm.3708
Ali M, Pulli B, Chen JW
Molecular imaging of macrophage enzyme activity in cardiac inflammation.
Curr Cardiovasc Imaging Rep. 2014;7(4):9258 - PMID: 24729833 - PMCID: PMC3979571 - DOI: 10.1007/s12410-014-9258-0
Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bø TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH, Straume O, Akslen LA, Watnick RS, Folkman J, Naumov GN
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors.
Mol Cancer Res. 2014;12(5):754-64 - PMID: 24574516 - PMCID: PMC4020951 - DOI: 10.1158/1541-7786.MCR-13-0532-T
Mietto C, Pinciroli R, Piriyapatsom A, Thomas JG, Bry L, Delaney ML, Du Bois A, Truelove J, Ackman JB, Wojtkiewicz GR, Nahrendorf M, Kacmarek RM, Berra L
Tracheal Tube Obstruction in Mechanically Ventilated Patients Assessed by High-resolution Computed Tomography.
Anesthesiology. 2014;121(6):1226-1235 - PMID: 25254903 - DOI: 10.1097/ALN.0000000000000455
Ausiello D, Shaw S
Quantitative human phenotyping: the next frontier in medicine.
Trans Am Clin Climatol Assoc. 2014;125:219-28 - PMID: 25125736 - PMCID: PMC4112685
Core AB, Canali S, Babitt JL
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis.
Front Pharmacol. 2014;5:104 - PMID: 24860505 - PMCID: PMC4026703 - DOI: 10.3389/fphar.2014.00104
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases.
Aliment Pharmacol Ther. 2014;39(10):1136-42 - PMID: 24641590 - PMCID: PMC4187206 - DOI: 10.1111/apt.12706
Wang CY, Meynard D, Lin HY
The role of TMPRSS6/matriptase-2 in iron regulation and anemia.
Front Pharmacol. 2014;5:114 - PMID: 24966834 - PMCID: PMC4053654 - DOI: 10.3389/fphar.2014.00114
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The 2013 symposium on pathology data integration and clinical decision support and the current state of field.
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Acquired Resistance to Crizotinib from a Mutation in CD74-ROS1.
New Engl J Med. 2013;368(25):2395-401 - PMID: 23724914 - PMCID: PMC3878821 - DOI: 10.1056/NEJMoa1215530
Steele DJ, Kasmar AG, Guimaraes AR, Dekker JP
Case records of the Massachusetts General Hospital. Case 3-2013. A 72-year-old woman with abdominal pain and distention after peritoneal dialysis.
New Engl J Med. 2013;368(4):375-85 - PMID: 23343067 - DOI: 10.1056/NEJMcpc1208142
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New Engl J Med. 2013;368(8):757-65 - PMID: 23425169 - DOI: 10.1056/NEJMcpc1208149
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Case records of the Massachusetts General Hospital. Case 25-2013. A 71-year-old man with hematuria and a mass in the bladder.
New Engl J Med. 2013;369(7):660-7 - PMID: 23944304 - DOI: 10.1056/NEJMcpc1209278
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Charting a dynamic DNA methylation landscape of the human genome.
Nature. 2013;500(7463):477-81 - PMID: 23925113 - PMCID: PMC3821869 - DOI: 10.1038/nature12433
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Dedifferentiation of committed epithelial cells into stem cells in vivo.
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Locus-specific editing of histone modifications at endogenous enhancers.
Nat Biotechnol. 2013;31(12):1133-6 - PMID: 24013198 - PMCID: PMC3858395 - DOI: 10.1038/nbt.2701
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Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.
Nat Biotechnol. 2013;31(10):898-907 - PMID: 24013197 - PMCID: PMC4058317 - DOI: 10.1038/nbt.2682
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Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.
Nat Biotechnol. 2013;31(12):1137-42 - PMID: 24108092 - PMCID: PMC3858462 - DOI: 10.1038/nbt.2726
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Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.
Cell. 2013;153(5):1149-1163 - PMID: 23664763 - PMCID: PMC3709577 - DOI: 10.1016/j.cell.2013.04.037
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Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues.
Cell. 2013;152(3):642-54 - PMID: 23333102 - PMCID: PMC3563935 - DOI: 10.1016/j.cell.2012.12.033
Chung HJ, Castro CM, Im H, Lee H*, Weissleder R*
A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria
Nat Nanotechnol. 2013;8(5):369-75 - PMID: 23644570 - PMCID: PMC3711657 - DOI: 10.1038/nnano.2013.70
Suvà ML, Riggi N, Bernstein BE
Epigenetic reprogramming in cancer.
Science. 2013;339(6127):1567-70 - PMID: 23539597 - PMCID: PMC3821556 - DOI: 10.1126/science.1230184
Swirski FK, Nahrendorf M
Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure.
Science. 2013;339(6116):161-6 - PMID: 23307733 - PMCID: PMC3891792 - DOI: 10.1126/science.1230719
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The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide.
Science. 2013;342(6161):971-6 - PMID: 24264990 - PMCID: PMC4048947 - DOI: 10.1126/science.1240537
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Therapeutically reeducating macrophages to treat GBM.
Nature Med. 2013;19(10):1207-1208 - PMID: 24100977 - DOI: 10.1038/nm.3355
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Local proliferation dominates lesional macrophage accumulation in atherosclerosis
Nature Med. 2013;19(9):1166-72 - PMID: 23933982 - PMCID: PMC3769444 - DOI: 10.1038/nm.3258
Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT
Differential regulation of myeloid leukemias by the bone marrow microenvironment.
Nature Med. 2013;19(11):1513-7 - PMID: 24162813 - PMCID: PMC3827980 - DOI: 10.1038/nm.3364
Silberstein LE, Lin CP
A new image of the hematopoietic stem cell vascular niche.
Cell Stem Cell. 2013;13(5):514-6 - PMID: 24209758 - PMCID: PMC4148778 - DOI: 10.1016/j.stem.2013.10.012
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In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.
Cancer Cell. 2013;24(1):45-58 - PMID: 23770013 - PMCID: PMC3746037 - DOI: 10.1016/j.ccr.2013.05.004
Bronte V, Pittet MJ
The spleen in local and systemic regulation of immunity.
Immunity. 2013;39(5):806-18 - PMID: 24238338 - PMCID: PMC3912742 - DOI: 10.1016/j.immuni.2013.10.010
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Angiotensin II Drives the Production of Tumor-Promoting Macrophages
Immunity. 2013;38(2):296-308 - PMID: 23333075 - PMCID: PMC3582771 - DOI: 10.1016/j.immuni.2012.10.015
Chapman S, Dobrovolskaia M, Farahani K, Goodwin A, Joshi A, Lee H, Meade T, Pomper M, Ptak K, Rao J, Singh R, Sridhar S, Stern S, Wang A, Weaver JB, Woloschak G, Yang L
Nanoparticles for cancer imaging: The good, the bad, and the promise.
Nano Today. 2013;8(5):454-460 - PMID: 25419228 - PMCID: PMC4240321 - DOI: 10.1016/j.nantod.2013.06.001
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Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice.
Circulation. 2013;127(20):2038-2046 - PMID: 23616627 - PMCID: PMC3661714 - DOI: 10.1161/CIRCULATIONAHA.112.000116
Kumar V, Patel N, Van Houzen N, Saini N
Brugada-type electrocardiographic changes induced by Fever.
Circulation. 2013;127(21):2145-6 - PMID: 23716383 - DOI: 10.1161/CIRCULATIONAHA.112.000901
van der Laan AM, Ter Horst EN, Delewi R, Begieneman MP, Krijnen PA, Hirsch A, Lavaei M, Nahrendorf M, Horrevoets AJ, Niessen HW, Piek JJ
Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir.
Eur Heart J. 2013;35(6):376-85 - PMID: 23966310 - PMCID: PMC3916776 - DOI: 10.1093/eurheartj/eht331
Im H, Bantz KC, Lee SH, Johnson TW, Haynes CL, Oh SH
Self-assembled plasmonic nanoring cavity arrays for SERS and LSPR biosensing.
Adv Mater. 2013;25(19):2678-85 - PMID: 23436239 - DOI: 10.1002/adma.201204283
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Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.
J Exp Med. 2013;210(12):2641-59 - PMID: 24218140 - PMCID: PMC3832937 - DOI: 10.1084/jem.20131141
Swirski FK, Nahrendorf M
Macrophage - stem cell crosstalk after myocardial infarction.
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In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.
J Am Coll Cardiol. 2013;63(15):1556-66 - PMID: 24361318 - PMCID: PMC3992176 - DOI: 10.1016/j.jacc.2013.11.023
Yang* KS, Budin* G, Tassa C, Kister O, Weissleder R
Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells
Angew Chem Int Ed Engl. 2013;52(40):10593-7 - PMID: 23960025 - PMCID: PMC3856564 - DOI: 10.1002/anie.201304096
Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R
BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes.
Angew Chem Int Ed Engl. 2013;52(27):6917-6920 - PMID: 23712730 - PMCID: PMC3875324 - DOI: 10.1002/anie.201301100
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SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing.
Dev Cell. 2013;26(6):565-577 - PMID: 24091011 - DOI: 10.1016/j.devcel.2013.08.016
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Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.
Gastroenterology. 2013;145(6):1347-57 - PMID: 23973919 - PMCID: PMC3840157 - DOI: 10.1053/j.gastro.2013.08.035
Rho J, Chung J, Im H, Liong M, Shao H, Castro CM, Weissleder R, Lee H
Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles.
ACS Nano. 2013;7(12):11227-33 - PMID: 24295203 - PMCID: PMC3898036 - DOI: 10.1021/nn405016y
Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, Charollais A, Ramadori P, Foti M, Meda P, Féraille E, Brown D, Hasler U
Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters.
Autophagy. 2013;9(4):550-67 - PMID: 23380587 - PMCID: PMC3627670 - DOI: 10.4161/auto.23662
Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH
Endoscopic Time-Lapse Imaging of Immune Cells in Infarcted Mouse Hearts.
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Swirski FK, Robbins CS
Neutrophils usher monocytes into sites of inflammation.
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Majmudar MD, Yoo J, Keliher E, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson D, Swirski FK, Weissleder R, Nahrendorf M
Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques.
Circ Res. 2013;112(5):755-61 - PMID: 23300273 - PMCID: PMC3586287 - DOI: 10.1161/CIRCRESAHA.111.300576 - Cover
Nahrendorf M, Swirski FK
Monocyte and macrophage heterogeneity in the heart.
Circ Res. 2013;112(12):1624-33 - PMID: 23743228 - PMCID: PMC3753681 - DOI: 10.1161/CIRCRESAHA.113.300890
Hideshima T, Mazitschek R, Santo L, Mimura N, Gorgun G, Richardson PG, Raje N, Anderson KC
Induction of differential apoptotic pathways in multiple myeloma cells by class selective histone deacetylase inhibitors.
Leukemia. 2013;28(2):457-60 - PMID: 24150220 - PMCID: PMC4405100 - DOI: 10.1038/leu.2013.301
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Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma.
Leukemia. 2013;28(3):680-9 - PMID: 23913134 - PMCID: PMC4165599 - DOI: 10.1038/leu.2013.231
Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW
Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.
Nat Commun. 2013;4:2189 - PMID: 23877263 - PMCID: PMC3740589 - DOI: 10.1038/ncomms3189
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Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.
Nat Commun. 2013;4:2532 - PMID: 24113571 - PMCID: PMC3826633 - DOI: 10.1038/ncomms3532
Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.
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Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H*, Weissleder R*
Magnetic barcode assay for genetic detection of pathogens
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Chen X, Park HR, Pelton M, Piao X, Lindquist NC, Im H, Kim YJ, Ahn JS, Ahn KJ, Park N, Kim DS, Oh SH
Atomic layer lithography of wafer-scale nanogap arrays for extreme confinement of electromagnetic waves.
Nat Commun. 2013;4:2361 - PMID: 23999053 - DOI: 10.1038/ncomms3361
Peterson VM*, Castro CM*, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R
Ascites analysis by a microfluidic chip allows tumor-cell profiling
Proc Natl Acad Sci U S A. 2013;110(51):E4978-86 - PMID: 24297935 - PMCID: PMC3870756 - DOI: 10.1073/pnas.1315370110
Liu Y, Shoji-Kawata S, Sumpter RM, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.
Proc Natl Acad Sci U S A. 2013;110(51):20364-71 - PMID: 24277826 - PMCID: PMC3870705 - DOI: 10.1073/pnas.1319661110
Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.
Proc Natl Acad Sci U S A. 2013;110(24):9776-81 - PMID: 23720309 - PMCID: PMC3683718 - DOI: 10.1073/pnas.1307478110
Miller MA, Meyer AS, Beste MT, Lasisi Z, Reddy S, Jeng KW, Chen CH, Han J, Isaacson K, Griffith LG, Lauffenburger DA
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling.
Proc Natl Acad Sci U S A. 2013;110(22):E2074-83 - PMID: 23674691 - PMCID: PMC3670354 - DOI: 10.1073/pnas.1222387110
Squadrito ML, Etzrodt M, De Palma M, Pittet MJ
MicroRNA-mediated control of macrophages and its implications for cancer.
Trends Immunol. 2013;34(7):350-9 - PMID: 23498847 - PMCID: PMC3700601 - DOI: 10.1016/j.it.2013.02.003
Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM
Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.
Ann Rheum Dis. 2013;73(6):1170-1175 - PMID: 23716066 - PMCID: PMC3815491 - DOI: 10.1136/annrheumdis-2012-203202
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mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation.
Blood. 2013;122(14):e23-e32 - PMID: 23980067 - PMCID: PMC3790516 - DOI: 10.1182/blood-2013-04-495119
Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ
Circulating CD34+ progenitor cell frequency is associated with clinical and genetic factors.
Blood. 2013;121(8):e50-6 - PMID: 23287867 - PMCID: PMC3578962 - DOI: 10.1182/blood-2012-05-424846
Meynard D, Babitt JL, Lin HY
The liver: conductor of systemic iron regulation.
Blood. 2013;123(2):168-76 - PMID: 24200681 - PMCID: PMC3888285 - DOI: 10.1182/blood-2013-06-427757
Brown D, Jenny Lu HA
Aquaporin-2 Inhibitors: Fishing in the Chemical Pool.
J Am Soc Nephrol. 2013;24(5):685-6 - PMID: 23599384 - DOI: 10.1681/ASN.2013030243
Wildgruber M, Swirski FK, Zernecke A
Molecular Imaging of Inflammation in Atherosclerosis.
Theranostics. 2013;3(11):865-884 - PMID: 24312156 - PMCID: PMC3841337 - DOI: 10.7150/thno.5771
Shan G, Weissleder R, Hilderbrand SA
Upconverting Organic Dye Doped Core-Shell Nano-Composites for Dual-Modality NIR Imaging and Photo-Thermal Therapy.
Theranostics. 2013;3(4):267-74 - PMID: 23606913 - PMCID: PMC3630527 - DOI: 10.7150/thno.5226
Jochems J, Boulden J, Lee BG, Blendy JA, Jarpe M, Mazitschek R, Van Duzer JH, Berton O
Antidepressant-Like Properties of Novel HDAC6 Selective Inhibitors with Improved Brain Bioavailability.
Neuropsychopharmacology. 2013;39(2):389-400 - PMID: 23954848 - PMCID: PMC3870780 - DOI: 10.1038/npp.2013.207
Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari KI, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J
Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1.
Cancer Res. 2013;74(3):738-50 - PMID: 24310399 - PMCID: PMC3928601 - DOI: 10.1158/0008-5472.CAN-13-2650
Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK
In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.
Nucleic Acids Res. 2013;41(19):e181 - PMID: 23945932 - PMCID: PMC3799455 - DOI: 10.1093/nar/gkt716
Huang J, McKee M, Huang HD, Xiang A, Davidson AJ, Lu HA
A zebrafish model of conditional targeted podocyte ablation and regeneration.
Kidney Int. 2013;83(6):1193-200 - PMID: 23466998 - PMCID: PMC3672345 - DOI: 10.1038/ki.2013.6
Pucci F, Pittet MJ
Molecular Pathways: Tumor-derived microvesicles and their interactions with immune cells in vivo.
Clin Cancer Res. 2013;19(10):2598-604 - PMID: 23426276 - PMCID: PMC3655093 - DOI: 10.1158/1078-0432.CCR-12-0962
Liu R, Rallo R, Weissleder R, Tassa C, Shaw S, Cohen Y
Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries.
Small. 2013;9(9-10):1842-52 - PMID: 23423856 - DOI: 10.1002/smll.201201903
Im H, Oh SH
Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges.
Small. 2013;10(4):680-4 - PMID: 24123889 - DOI: 10.1002/smll.201301475
Im H, Oh SH
Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges.
Small. 2013;10(4):680-4 - PMID: 24123889 - DOI: 10.1002/smll.201301475
Meyer AS, Miller MA, Gertler FB, Lauffenburger DA
The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells.
Sci Signal. 2013;6(287):ra66 - PMID: 23921085 - PMCID: PMC3947921 - DOI: 10.1126/scisignal.2004155
Courties G, Moskowitz MA, Nahrendorf M
The Innate Immune System After Ischemic Injury: Lessons to Be Learned From the Heart and Brain.
JAMA Neurol. 2013;71(2):233-6 - PMID: 24296962 - PMCID: PMC3946050 - DOI: 10.1001/jamaneurol.2013.5026
Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE
An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma.
Cell Rep. 2013;3(5):1567-1579 - PMID: 23707066 - PMCID: PMC3774301 - DOI: 10.1016/j.celrep.2013.04.021
Breton S, Brown D
Regulation of Luminal Acidification by the V-ATPase.
Physiology (Bethesda). 2013;28(5):318-29 - PMID: 23997191 - PMCID: PMC3768094 - DOI: 10.1152/physiol.00007.2013
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Association Between Reduced Plasma 25-hydroxy Vitamin D and Increased Risk of Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2013;12(5):821-7 - PMID: 24161349 - PMCID: PMC3995841 - DOI: 10.1016/j.cgh.2013.10.011
Kumar V, Donahue DM, Patel N
An unexpected complication during cardiac catheterization: blood clot cast of the tracheobronchial tree: first case during cardiac catheterization.
JACC Cardiovasc Interv. 2013;6(4):e19 - PMID: 23597616 - DOI: 10.1016/j.jcin.2012.11.007
Agasti SS, Laughney AM, Kohler RH, Weissleder R
A photoactivatable drug–caged fluorophore conjugate allows direct quantification of intracellular drug transport
Chem Commun. 2013;49(94):11050-2 - PMID: 24135896 - PMCID: PMC3856557 - DOI: 10.1039/c3cc46089d
Turan S, Fernandez-Rebollo E, Aydin C, Zoto T, Reyes M, Bounoutas G, Chen M, Weinstein LS, Erben RG, Marshansky V, Bastepe M
Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone-resistance due to heterozygous Gαs disruption.
J Bone Miner Res. 2013;29(3):749-60 - PMID: 23956044 - PMCID: PMC3926912 - DOI: 10.1002/jbmr.2070
Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H
Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells.
Lab Chip. 2013;14(1):14-23 - PMID: 23835814 - PMCID: PMC3844052 - DOI: 10.1039/c3lc50621e
Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX
Stress-induced hematopoietic failure in the absence of immediate early response gene X-1.
Haematologica. 2013;99(2):282-91 - PMID: 24056813 - PMCID: PMC3912958 - DOI: 10.3324/haematol.2013.092452
Issadore D*, Chung HJ*, Chung J, Budin G, Weissleder R*, Lee H*
μHall Chip for Sensitive Detection of Bacteria
Adv Healthc Mater. 2013;2(9):1224-8 - PMID: 23495188 - PMCID: PMC4340655 - DOI: 10.1002/adhm.201200380
Ueno T, Dutta P, Keliher E, Leuschner F, Majmudar M, Marinelli B, Iwamoto Y, Figueiredo JL, Christen T, Swirski FK, Libby P, Weissleder R, Nahrendorf M
Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts.
Circ Cardiovasc Imaging. 2013;6(4):568-73 - PMID: 23771986 - PMCID: PMC3734553 - DOI: 10.1161/CIRCIMAGING.113.000481
Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE
Fluorescence Tomography of Rapamycin-Induced Autophagy and Cardioprotection In Vivo.
Circ Cardiovasc Imaging. 2013;6(3):441-7 - PMID: 23537953 - PMCID: PMC3805276 - DOI: 10.1161/CIRCIMAGING.112.000074
Zeglis BM, Sevak KK, Reiner T, Mohindra P, Carlin SD, Zanzonico P, Weissleder R, Lewis JS
A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry.
J Nucl Med. 2013;54(8):1389-96 - PMID: 23708196 - PMCID: PMC4151562 - DOI: 10.2967/jnumed.112.115840
Frantz S, Hofmann U, Fraccarollo D, Schäfer A, Kranepuhl S, Hagedorn I, Nieswandt B, Nahrendorf M, Wagner H, Bayer B, Pachel C, Schön MP, Kneitz S, Bobinger T, Weidemann F, Ertl G, Bauersachs J
Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction.
FASEB J. 2013;27(3):871-81 - PMID: 23159933 - DOI: 10.1096/fj.12-214049
Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R
Targeting cathepsin e in pancreatic cancer by a small molecule allows in vivo detection.
Neoplasia. 2013;15(7):684-93 - PMID: 23814481 - PMCID: PMC3689232 - Cover
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ
Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules.
ACS Chem Biol. 2013;8(12):2724-33 - PMID: 24168452 - PMCID: PMC3951132 - DOI: 10.1021/cb400352d
Libby P, Nahrendorf M, Swirski FK
Monocyte heterogeneity in cardiovascular disease.
Semin Immunopathol. 2013;35(5):553-62 - PMID: 23839097 - PMCID: PMC3755757 - DOI: 10.1007/s00281-013-0387-3
Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM
Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and miniaturized micro-NMR system.
Nanomedicine (Lond). 2013;9(7):1009-17 - PMID: 23570873 - PMCID: PMC4330975 - DOI: 10.1016/j.nano.2013.03.011
McCarthy JR
Book review: the handbook of nanomedicine (2nd edition).
Nanomedicine (Lond). 2013;8(2):173-5 - PMID: 23394153
Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP
Normalization of Plasma 25-Hydroxy Vitamin D Is Associated with Reduced Risk of Surgery in Crohn's Disease.
Inflamm Bowel Dis. 2013;19(9):1921-1927 - PMID: 23751398 - PMCID: PMC3720838 - DOI: 10.1097/MIB.0b013e3182902ad9
Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA
Fluorescence Endoscopy of Cathepsin Activity Discriminates Dysplasia from Colitis.
Inflamm Bowel Dis. 2013;19(7):1339-1345 - PMID: 23591598 - PMCID: PMC4306589 - DOI: 10.1097/MIB.0b013e318281f3f8
Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D,
Defining Kidney Biology to Understand Renal Disease.
Clin J Am Soc Nephrol. 2013;9(4):809-11 - PMID: 24370769 - PMCID: PMC3974369 - DOI: 10.2215/CJN.10851013
Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD, Hallows KR, Brown D, Bouley R, Vilardaga JP
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.
J Biol Chem. 2013;288(39):27849-60 - PMID: 23935101 - PMCID: PMC3784700 - DOI: 10.1074/jbc.M112.445098
Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Gruber G, Marshansky V
The N-terminus of a-Subunit Isoforms is Involved in Signaling between V-ATPase and Cytohesin-2.
J Biol Chem. 2013;288(8):5896-913 - PMID: 23288846 - PMCID: PMC3581410 - DOI: 10.1074/jbc.M112.409169
Clardy SM, Keliher EJ, Mohan JF, Sebas M, Benoist C, Mathis D, Weissleder R
Fluorescent Exendin-4 Derivatives for Pancreatic β-Cell Analysis.
Bioconjug Chem. 2013;25(1):171-177 - PMID: 24328216 - PMCID: PMC4016126 - DOI: 10.1021/bc4005014
Paly JJ, Efstathiou JA, Hedgire SS, Chung PW, O'Malley M, Shah A, Bekelman JE, Harisinghani M, Shipley WU, Zietman AL, Beard C
Mapping patterns of nodal metastases in seminoma: Rethinking radiotherapy fields.
Radiother Oncol. 2013;106(1):64-8 - PMID: 23321493 - DOI: 10.1016/j.radonc.2012.12.002 - Cover
Yuan Y, Andronesi OC, Bortfeld TR, Richter C, Wolf R, Guimaraes AR, Hong TS, Seco J
Feasibility study of in vivo MRI based dosimetric verification of proton end-of-range for liver cancer patients.
Radiother Oncol. 2013;106(3):378-82 - PMID: 23473960 - DOI: 10.1016/j.radonc.2013.01.016
Bhatia RS, Kumar V, Picard MH, Weiner RB
Comparison of the 2008 and 2011 appropriate use criteria for stress echocardiography.
J Am Soc Echocardiogr. 2013;26(4):339-43 - PMID: 23313389 - DOI: 10.1016/j.echo.2012.12.001
Faris JE, Blaszkowsky LS, McDermott S, Guimaraes AR, Szymonifka J, Huynh MA, Ferrone CR, Wargo JA, Allen JN, Dias LE, Kwak EL, Lillemoe KD, Thayer SP, Murphy JE, Zhu AX, Sahani DV, Wo JY, Clark JW, Fernandez-Del Castillo C, Ryan DP, Hong TS
FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience.
Oncologist. 2013;18(5):543-548 - PMID: 23657686 - PMCID: PMC3662845 - DOI: 10.1634/theoncologist.2012-0435
Lameijer MA, Tang J, Nahrendorf M, Beelen RH, Mulder WJ
Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease.
Expert Rev Mol Diagn. 2013;13(6):567-80 - PMID: 23895127 - PMCID: PMC4110962 - DOI: 10.1586/14737159.2013.819216
Swirski FK, Nahrendorf M
Imaging macrophage development and fate in atherosclerosis and myocardial infarction.
Immunol Cell Biol. 2013;91(4):297-303 - PMID: 23207281 - PMCID: PMC3875224 - DOI: 10.1038/icb.2012.72
Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW
Lipid and lipoprotein levels and trends in rheumatoid arthritis compared to the general population.
Arthritis Care Res (Hoboken). 2013;65(12):2046-50 - PMID: 23925980 - PMCID: PMC4060244 - DOI: 10.1002/acr.22091
Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, Wojtkiewicz G, Linnoila JJ, Chen JW
Measuring myeloperoxidase activity in biological samples.
PLoS ONE. 2013;8(7):e67976 - PMID: 23861842 - PMCID: PMC3702519 - DOI: 10.1371/journal.pone.0067976
Prabhakar S, Goto J, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO
Stochastic model of tsc1 lesions in mouse brain.
PLoS ONE. 2013;8(5):e64224 - PMID: 23696872 - PMCID: PMC3655945 - DOI: 10.1371/journal.pone.0064224
Rice WL, Van Hoek AN, Păunescu TG, Huynh C, Goetze B, Singh B, Scipioni L, Stern LA, Brown D
High resolution helium ion scanning microscopy of the rat kidney.
PLoS ONE. 2013;8(3):e57051 - PMID: 23505418 - PMCID: PMC3591388 - DOI: 10.1371/journal.pone.0057051
Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerté M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR
Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma.
PLoS ONE. 2013;8(3):e60156 - PMID: 23527308 - PMCID: PMC3603933 - DOI: 10.1371/journal.pone.0060156
Mortensen LJ, Levy O, Phillips JP, Stratton T, Triana B, Ruiz JP, Gu F, Karp JM, Lin CP
Quantification of Mesenchymal Stem Cell (MSC) Delivery to a Target Site Using In Vivo Confocal Microscopy.
PLoS ONE. 2013;8(10):e78145 - PMID: 24205131 - PMCID: PMC3812161 - DOI: 10.1371/journal.pone.0078145
Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR
Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells.
PLoS ONE. 2013;8(7):e67590 - PMID: 23844039 - PMCID: PMC3699654 - DOI: 10.1371/journal.pone.0067590
Giedt RJ, Koch PD, Weissleder R
Single Cell Analysis of Drug Distribution by Intravital Imaging.
PLoS ONE. 2013;8(4):e60988 - PMID: 23593370 - PMCID: PMC3622689 - DOI: 10.1371/journal.pone.0060988
Meynard D, Sun CC, Wu Q, Chen W, Chen S, Nelson CN, Waters MJ, Babitt JL, Lin HY
Inflammation Regulates TMPRSS6 Expression via STAT5.
PLoS ONE. 2013;8(12):e82127 - PMID: 24376517 - PMCID: PMC3871639 - DOI: 10.1371/journal.pone.0082127
Kim E, Yang K, Weissleder R
Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET
PLoS ONE. 2013;8 (11):e81275 - PMID: 24265843 - PMCID: PMC3827223 - DOI: 10.1371/journal.pone.0081275
Carlson AL, Fujisaki J, Wu J, Runnels JM, Turcotte R, Spencer JA, Celso CL, Scadden DT, Strom TB, Lin CP
Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.
PLoS ONE. 2013;8(8):e69257 - PMID: 23990881 - PMCID: PMC3753322 - DOI: 10.1371/journal.pone.0069257
Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL
Modeling disease severity in multiple sclerosis using electronic health records.
PLoS ONE. 2013;8(11):e78927 - PMID: 24244385 - PMCID: PMC3823928 - DOI: 10.1371/journal.pone.0078927
Roy JW, Hill E, Ruan YC, Vedovelli L, Paunescu T, Brown D, Breton S
Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis.
Am J Physiol Cell Physiol. 2013;305(4):C436-46 - PMID: 23761626 - PMCID: PMC3891217 - DOI: 10.1152/ajpcell.00410.2012
Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS
Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors.
Atherosclerosis. 2013;229(1):228-233 - PMID: 23701996 - PMCID: PMC3984590 - DOI: 10.1016/j.atherosclerosis.2013.04.017
Paunescu TG, Lu HA, Russo LM, Pastor-Soler NM, McKee M, McLaughlin MM, Bartlett BE, Breton S, Brown D
Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells.
Am J Physiol Renal Physiol. 2013;305(12):F1783-F1795 - PMID: 24133120 - PMCID: PMC3882446 - DOI: 10.1152/ajprenal.00622.2012
Shum W, Hill E, Brown D, Breton S
Plasticity of basal cells during postnatal development in the rat epididymis.
Reproduction. 2013;146(5):455-469 - PMID: 23960170 - PMCID: PMC4106237 - DOI: 10.1530/REP-12-0510
Sun CC, Vaja V, Chen S, Theurl I, Stepanek A, Brown DE, Cappellini MD, Weiss G, Hong CC, Lin HY, Babitt JL
A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats.
Nephrol Dial Transplant. 2013;28(7):1733-1743 - PMID: 23345622 - PMCID: PMC3707526 - DOI: 10.1093/ndt/gfs584
Zumbrennen-Bullough K, Babitt JL
The iron cycle in CKD: from genetics and experimental models to CKD patients.
Nephrol Dial Transplant. 2013;29(2):263-73 - PMID: 24235084 - PMCID: PMC3910345 - DOI: 10.1093/ndt/gft443
Chung J*, Issadore D*, Ullal A*, Lee K, Weissleder R*, Lee H*
Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip
Biomicrofluidics. 2013;7(5):54107 - PMID: 24404070 - PMCID: PMC3790798 - DOI: 10.1063/1.4821923
Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R
Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging.
Biomed Opt Express. 2013;4(10):2095-106 - PMID: 24156067 - PMCID: PMC3799669 - DOI: 10.1364/BOE.4.002095
Preston MA, Harisinghani MG, Mucci L, Witiuk K, Breau RH
Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancer.
BJU Int. 2013;111(3):514-7 - PMID: 23320634 - DOI: 10.1111/j.1464-410X.2012.11447.x
McDermott S, Thayer SP, Fernandez-Del Castillo C, Mino-Kenudson M, Weissleder R, Harisinghani MG
Accurate prediction of nodal status in preoperative patients with pancreatic ductal adenocarcinoma using next-gen nanoparticle.
Transl Oncol. 2013;6(6):670-5 - PMID: 24466369 - PMCID: PMC3890701
Hedgire SS, McDermott S, Borczuk D, Elmi A, Saini S, Harisinghani MG
The Spectrum of IgG4-Related Disease in the Abdomen and Pelvis.
AJR Am J Roentgenol. 2013;201(1):14-22 - PMID: 23789654 - DOI: 10.2214/AJR.12.9995
Gunn AJ, Seethamraju RT, Hedgire S, Elmi A, Daniels GH, Harisinghani MG
Imaging Behavior of the Normal Adrenal on Ferumoxytol-Enhanced MRI: Preliminary Findings.
AJR Am J Roentgenol. 2013;201(1):117-21 - PMID: 23789664 - DOI: 10.2214/AJR.12.9357
Dhyani M, Anupindi SA, Ayyala R, Hahn PF, Gee MS
Defining an imaging algorithm for noncystic splenic lesions identified in young patients.
AJR Am J Roentgenol. 2013;201(6):W893-9 - PMID: 24261396 - DOI: 10.2214/AJR.12.10105
Rajesh A, Cloud G, Harisinghani MG
Improving the quality of manuscript reviews: impact of introducing a structured electronic template to submit reviews.
AJR Am J Roentgenol. 2013;200(1):20-3 - PMID: 23255737 - DOI: 10.2214/AJR.11.8299
Pestana N, Mortensen LJ, Runnels JP, Vickers D, Murthy SK, Lin CP, Niedre M
Improved diffuse fluorescence flow cytometer prototype for high sensitivity detection of rare circulating cells in vivo.
J Biomed Opt. 2013;18(7):77002 - PMID: 23831714 - PMCID: PMC3702234 - DOI: 10.1117/1.JBO.18.7.077002
Lartey FM, Ahn GO, Shen B, Cord KT, Smith T, Chua JY, Rosenblum S, Liu H, James ML, Chernikova S, Lee SW, Pisani LJ, Tirouvanziam R, Chen JW, Palmer TD, Chin FT, Guzman R, Graves EE, Loo BW
PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [(18)F]PBR06.
Mol Imaging Biol. 2013;16(1):109-17 - PMID: 23836504 - PMCID: PMC4141125 - DOI: 10.1007/s11307-013-0664-5
Wang H, Albadawi H, Siddiquee Z, Stone JM, Panchenko MP, Watkins MT, Stone JR
Altered vascular activation due to deficiency of the NADPH oxidase component p22(phox.)
Cardiovasc Pathol. 2013;23(1):35-42 - PMID: 24035466 - DOI: 10.1016/j.carpath.2013.08.003
Mitchell DG, Javitt MC, Glanc P, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Horowitz NS, Pandharipande PV, Pannu HK, Podrasky AE, Royal HD, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM
ACR Appropriateness Criteria Staging and Follow-up of Ovarian Cancer.
J Am Coll Radiol. 2013;10(11):822-7 - PMID: 24183551 - DOI: 10.1016/j.jacr.2013.07.017
Quencer KB, Nimkin K, Mino-Kenudson M, Gee MS
Detecting active inflammation and fibrosis in pediatric Crohn's disease: prospective evaluation of MR-E and CT-E.
Abdom Imaging. 2013;38(4):705-13 - PMID: 23361877 - PMCID: PMC4390174 - DOI: 10.1007/s00261-013-9981-z
Weber GF, Swirski FK
Immunopathogenesis of abdominal sepsis.
Langenbecks Arch Surg. 2013;399(1):1-9 - PMID: 24121723 - DOI: 10.1007/s00423-013-1129-7
van der Laan AM, Nahrendorf M, Piek JJ
Republished: Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response.
Postgrad Med J. 2013;89(1047):52-8 - PMID: 23257717 - DOI: 10.1136/postgradmedj-2012-301623rep
Oklu R, Deipolyi AR, Wicky S, Ergul E, Deik AA, Chen JW, Hirsch JA, Wojtkiewicz GR, Clish CB
Identification of small compound biomarkers of pituitary adenoma: a bilateral inferior petrosal sinus sampling study.
J Neurointerv Surg. 2013;6(7):541-6 - PMID: 24005126 - DOI: 10.1136/neurintsurg-2013-010821
González RG, Copen WA, Schaefer PW, Lev MH, Pomerantz SR, Rapalino O, Chen JW, Hunter GJ, Romero JM, Buchbinder BR, Larvie M, Hirsch JA, Gupta R
The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach.
J Neurointerv Surg. 2013;5 Suppl 1:i7-i12 - PMID: 23493340 - PMCID: PMC3623036 - DOI: 10.1136/neurintsurg-2013-010715
Podrasky AE, Javitt MC, Glanc P, Dubinsky T, Harisinghani MG, Harris RD, Khati NJ, Mitchell DG, Pandharipande PV, Pannu HK, Shipp TD, Siegel CL, Simpson L, Wall DJ, Wong-You-Cheong JJ, Zelop CM
ACR Appropriateness Criteria® Second and Third Trimester Bleeding.
Ultrasound Q. 2013;29(4):293-301 - PMID: 24263752 - DOI: 10.1097/RUQ.0000000000000044
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY
Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications.
J Vis Exp. 2013;(79):e50772 - PMID: 24084440 - PMCID: PMC3924759 - DOI: 10.3791/50772
Mackay DD, Huesmann GR, Wu RI, Stone JR, Pless ML
Giant Cell Arteritis Causing Symmetric Bilateral Posterior Circulation Infarcts.
J Clin Rheumatol. 2013;19(7):393-6 - PMID: 24048110 - DOI: 10.1097/RHU.0b013e3182a6ffc1
Hedgire SS, Sainani NI, McDermott S, Hahn PF, Harisinghani MG
Mono-belly and beyond: spectrum of imaging manifestations of EBV infection in the abdomen.
Clin Imaging. 2013;37(4):711-7 - PMID: 23317894 - DOI: 10.1016/j.clinimag.2012.10.003
Yoon TJ, Shao H, Weissleder R, Lee H
Oxidation Kinetics and Magnetic Properties of Elemental Iron Nanoparticles
Part. Part. Syst. Charact. 2013;30:667–671 - PMID: 24077230 - PMCID: PMC3783348 - DOI: 10.1002/ppsc.201300013
Schietinger A, Arina A, Liu RB, Wells S, Huang J, Engels B, Bindokas V, Bartkowiak T, Lee D, Herrmann A, Piston DW, Pittet MJ, Lin PC, Zal T, Schreiber H
Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer.
OncoImmunology. 2013;2(11):e26677 - PMID: 24482750 - PMCID: PMC3895414 - DOI: 10.4161/onci.26677
Cortez-Retamozo V, Engblom C, Pittet MJ
Remote control of macrophage production by cancer.
OncoImmunology. 2013;2(5):e24183 - PMID: 23762799 - PMCID: PMC3667905 - DOI: 10.4161/onci.24183
Coffey SE, Giedt RJ, Weissleder R
Automated analysis of clonal cancer cells by intravital imaging.
Intravital. 2013;2(3):ePub - PMID: 24349895 - PMCID: PMC3859690 - DOI: 10.4161/intv.26138
Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerte' M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR
Soluble Guanylate Cyclase a1-Deficient Mice: a novel murine model for Primary Open Angle Glaucoma.
2013;20(2):65-6 - PMID: 25206015 - PMCID: PMC4117107 - DOI: 10.5214/ans.0972.7531.200207
Stone JH, Patel VI, Oliveira GR, Stone JR
Case 38-2012.
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Bazari H, Guimaraes AR, Kushner YB
Case records of the Massachusetts General Hospital. Case 20-2012. A 77-year-old man with leg edema, hematuria, and acute renal failure.
New Engl J Med. 2012;366(26):2503-15 - PMID: 22738101 - DOI: 10.1056/NEJMcpc1111577
Hunt DP, Becker AE, Guimaraes AR, Stemmer-Rachamimov A, Misdraji J
Case records of the Massachusetts General Hospital. Case 21-2012. A 27-year-old man with fatigue, weakness, weight loss, and decreased libido.
New Engl J Med. 2012;367(2):157-69 - PMID: 22784119 - DOI: 10.1056/NEJMcpc1110053
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Case records of the Massachusetts General Hospital. Case 9-2012. A 67-year-old man with a persistently elevated PSA level.
New Engl J Med. 2012;366(12):1143-50 - PMID: 22435374 - DOI: 10.1056/NEJMcpc1104320
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Case records of the Massachusetts General Hospital. Case 25-2012. A 15-year-old boy with abdominal pain, hematochezia, and anemia.
New Engl J Med. 2012;367(7):659-67 - PMID: 22894579 - DOI: 10.1056/NEJMcpc1111578
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Nature. 2012;489(7414):57-74 - PMID: 22955616 - PMCID: PMC3439153 - DOI: 10.1038/nature11247
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Myocardial infarction accelerates atherosclerosis
Nature. 2012;487(7407):325-9 - PMID: 22763456 - PMCID: PMC3401326 - DOI: 10.1038/nature11260
Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL
Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.
Nature. 2012;489(7414):155-9 - PMID: 22820254 - PMCID: PMC3991463 - DOI: 10.1038/nature11303
Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H
DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.
Cell. 2012;149(7):1474-87 - PMID: 22726435 - DOI: 10.1016/j.cell.2012.04.035
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, Macdonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R
The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism.
Cell. 2012;151(6):1185-99 - PMID: 23217706 - PMCID: PMC3526953 - DOI: 10.1016/j.cell.2012.10.047
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, Depinho RA
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism.
Cell. 2012;149(3):656-70 - PMID: 22541435 - PMCID: PMC3472002 - DOI: 10.1016/j.cell.2012.01.058
Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.
Nat Nanotechnol. 2012;7(6):389-93 - PMID: 22659608 - PMCID: PMC3898745 - DOI: 10.1038/nnano.2012.73
Ryan RJ, Bernstein BE
Molecular biology. Genetic events that shape the cancer epigenome.
Science. 2012;336(6088):1513-4 - PMID: 22723401 - DOI: 10.1126/science.1223730
Rauch PJ*, Chudnovskiy A*, Robbins CS*, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK
Innate Response Activator B Cells Protect Against Microbial Sepsis
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Diagnostic Accuracy of Fractional Flow Reserve From Anatomic CT Angiography.
JAMA. 2012;:1-9 - PMID: 22922562 - PMCID: PMC4281479 - DOI: 10.1001/2012.jama.11274
Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R*, Lee H*
Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
Nature Med. 2012;18(12):1835-1840 - PMID: 23142818 - PMCID: PMC3518564 - DOI: 10.1038/nm.2994
Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D
Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging.
Nat Immunol. 2012;13(4):361-8 - PMID: 22366893 - PMCID: PMC3309063 - DOI: 10.1038/ni.2233 - Cover
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT
Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration.
Cell Stem Cell. 2012;10(3):259-72 - PMID: 22385654 - PMCID: PMC3652251 - DOI: 10.1016/j.stem.2012.02.003
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ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression.
Cancer Cell. 2012;22(2):180-93 - PMID: 22897849 - PMCID: PMC3422511 - DOI: 10.1016/j.ccr.2012.06.032
Rheinbay E, Louis DN, Bernstein BE, Suvà ML
A Tell-Tail Sign of Chromatin: Histone Mutations Drive Pediatric Glioblastoma.
Cancer Cell. 2012;21(3):329-331 - PMID: 22439930 - DOI: 10.1016/j.ccr.2012.03.001
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA
Programming human pluripotent stem cells into white and brown adipocytes.
Nat Cell Biol. 2012;14(2):209-19 - PMID: 22246346 - PMCID: PMC3385947 - DOI: 10.1038/ncb2411
Swirski FK, Nahrendorf M, Libby P
The ins and outs of inflammatory cells in atheromata.
Cell Metab. 2012;15(2):135-6 - PMID: 22326216 - DOI: 10.1016/j.cmet.2012.01.012
Issadore D, Chung J*, Shao H*, Liong M, Ghazani AA, Castro CM, Weissleder R*, Lee H*
Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector
Sci Transl Med. 2012;4 (141):141ra92 - PMID: 22764208 - PMCID: PMC3603277 - DOI: 10.1126/scitranslmed.3003747 - Cover
Wood DK, Soriano A, Mahadevan L, Higgins JM, Bhatia SN
A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease.
Sci Transl Med. 2012;4(123):123ra26 - PMID: 22378926 - PMCID: PMC3633235 - DOI: 10.1126/scitranslmed.3002738 - Cover
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A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals.
Mol Cell. 2012;47(5):810-22 - PMID: 22940246 - PMCID: PMC3873101 - DOI: 10.1016/j.molcel.2012.07.030
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Lack of Microsomal Prostaglandin E2 Synthase-1 in Bone Marrow Derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality after Acute Myocardial Infarction.
Circulation. 2012;125(23):2904-13 - PMID: 22589381 - DOI: 10.1161/CIRCULATIONAHA.112.099754
Moon H, Park HE, Kang J, Lee H, Cheong C, Lim YT, Ihm SH, Seung KB, Jaffer FA, Narula J, Chang K, Hong KS
Noninvasive Assessment of Myocardial Inflammation by Cardiovascular Magnetic Resonance in a Rat Model of Experimental Autoimmune Myocarditis.
Circulation. 2012;125(21):2603-12 - PMID: 22550157 - DOI: 10.1161/CIRCULATIONAHA.111.075283
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ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
Genome Res. 2012;22(9):1813-31 - PMID: 22955991 - PMCID: PMC3431496 - DOI: 10.1101/gr.136184.111
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Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis.
J Exp Med. 2012;209(1):123-37 - PMID: 22213805 - PMCID: PMC3260875 - DOI: 10.1084/jem.20111009
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PET/MRI of Inflammation in Myocardial Infarction
J Am Coll Cardiol. 2012;59:153-163 - PMID: 22222080 - PMCID: PMC3257823 - DOI: 10.1016/j.jacc.2011.08.066
Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R
Synthesis of [(18) F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging.
Angew Chem Int Ed Engl. 2012;51(19):4603-6 - PMID: 22473535 - PMCID: PMC3343182 - DOI: 10.1002/anie.201107957
Budin G*, Chung HJ*, Lee H, Weissleder R
A Magnetic Gram Stain for Bacterial Detection.
Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380 - DOI: 10.1002/anie.201202982
Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R
Bioorthogonal Imaging of Aurora Kinase A in Live Cells.
Angew Chem Int Ed Engl. 2012;51(27):6598-603 - PMID: 22644700 - PMCID: PMC3523717 - DOI: 10.1002/anie.201200994
Xu C, Miranda-Nieves D, Ankrum JA, Matthiesen ME, Phillips J, Roes I, Wojtkiewicz GR, Juneja V, Kultima JR, Zhao W, Vemula PK, Lin CP, Nahrendorf M, Karp JM
Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles.
Nano Lett. 2012;12(8):4131-9 - PMID: 22769232 - PMCID: PMC3552518 - DOI: 10.1021/nl301658q
Epa VC, Burden FR, Tassa C, Weissleder R, Shaw SY, Winkler DA
Modelling biological activities of nanoparticles.
Nano Lett. 2012;12(11):5808-5812 - PMID: 23039907 - DOI: 10.1021/nl303144k
Keller TL, Zocco D, Sundrud MS, Hendrick M, Edenius M, Yum J, Kim YJ, Lee HK, Cortese JF, Wirth DF, Dignam JD, Rao A, Yeo CY, Mazitschek R, Whitman M
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase
Nat Chem Biol. 2012;8(3):311-7 - PMID: 22327401 - PMCID: PMC3281520 - DOI: 10.1038/nchembio.790
Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V
Evidence for bistable bacteria-neutrophil interaction and its clinical implications.
J Clin Invest. 2012;122(8):3002-11 - PMID: 22820292 - PMCID: PMC3408731 - DOI: 10.1172/JCI59832
Lau KS, Cortez-Retamozo V, Philips SR, Pittet MJ, Lauffenburger DA, Haigis KM
Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium
PLoS Biol. 2012;10(9):e1001393 - PMID: 23055830 - PMCID: PMC3463506 - DOI: 10.1371/journal.pbio.1001393
Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
Gene Dev. 2012;26(24):2802-16 - PMID: 23249739 - PMCID: PMC3533082 - DOI: 10.1101/gad.207142.112
Min C, Shao H, Liong M, Yoon TJ, Weissleder R, Lee H
Mechanism of Magnetic Relaxation Switching Sensing.
ACS Nano. 2012;6(8):6821-8 - PMID: 22762250 - PMCID: PMC3429660 - DOI: 10.1021/nn301615b
Peterson VM, Castro CM, Lee H, Weissleder R
Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing.
ACS Nano. 2012;6(4):3506-13 - PMID: 22424443 - PMCID: PMC3337350 - DOI: 10.1021/nn300536y
Courties G, Nahrendorf M
Enlightened stem cells in the heart: more efficient and safer reporter gene imaging.
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Over a hump for imaging atherosclerosis: nanobodies visualize vascular cell adhesion molecule-1 in inflamed plaque.
Circ Res. 2012;110(7):902-3 - PMID: 22461358 - DOI: 10.1161/CIRCRESAHA.112.267260
Chen CH, Miller MA, Sarkar A, Beste MT, Isaacson KB, Lauffenburger DA, Griffith LG, Han J
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis.
J Am Chem Soc. 2012;135(5):1645-8 - PMID: 23157326 - PMCID: PMC3566300 - DOI: 10.1021/ja307866z
Agasti SS, Liong M, Peterson VM, Lee H, Weissleder R
Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cell.
J Am Chem Soc. 2012;134(45):18499-18502 - PMID: 23092113 - PMCID: PMC3498844 - DOI: 10.1021/ja307689w
Niers JM*, Chen JW*, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA
Single Reporter for Targeted Multimodal in Vivo Imaging.
J Am Chem Soc. 2012;134(11):5149-56 - PMID: 22397453 - PMCID: PMC3310895 - DOI: 10.1021/ja209868g
Mendenhall EM, Bernstein BE
DNA-protein interactions in high definition.
Genome Biol. 2012;13(1):139 - PMID: 22283870 - PMCID: PMC3334573 - DOI: 10.1186/gb-2012-13-1-139
Ku M, Jaffe JD, Koche RP, Rheinbay E, Endoh M, Koseki H, Carr SA, Bernstein BE
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions.
Genome Biol. 2012;13(10):R85 - PMID: 23034477 - PMCID: PMC3491413 - DOI: 10.1186/gb-2012-13-10-r85
Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivovarov M, Sbarbati A, Nahrendorf M, Weissleder R
Real-time in vivo imaging of the beating mouse heart at microscopic resolution
Nat Commun. 2012;3:1054 - PMID: 22968700 - PMCID: PMC3622400 - DOI: 10.1038/ncomms2060
Polasek M, Fuchs BC, Uppal R, Schühle DT, Alford JK, Loving GS, Yamada S, Wei L, Lauwers GY, Guimaraes AR, Tanabe KK, Caravan P
Molecular MR Imaging of Liver Fibrosis: A Feasibility Study using Rat and Mouse Models.
J Hepatol. 2012;57(3):549-55 - PMID: 22634342 - PMCID: PMC3423553 - DOI: 10.1016/j.jhep.2012.04.035
Lee S, Johnson TW, Lindquist NC, Im H, Norris DJ, Oh SH
Linewidth-Optimized Extraordinary Optical Transmission in Water with Template-Stripped Metallic Nanohole Arrays
Adv Funct Mater. 2012;22(21):4439-4446
Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L
TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.
Proc Natl Acad Sci U S A. 2012;109(41):16618-23 - PMID: 22996328 - PMCID: PMC3478596 - DOI: 10.1073/pnas.1117610109
Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, Yarmush ML, Parekkadan B
Implantable microenvironments to attract hematopoietic stem/cancer cells.
Proc Natl Acad Sci U S A. 2012;109(48):19638-43 - PMID: 23150542 - PMCID: PMC3511730 - DOI: 10.1073/pnas.1208384109
Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ
Origins of tumor-associated macrophages and neutrophils.
Proc Natl Acad Sci U S A. 2012;109(7):2491-6 - PMID: 22308361 - PMCID: PMC3289379 - DOI: 10.1073/pnas.1113744109
Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R
Reactive polymer enables efficient in vivo bioorthogonal chemistry.
Proc Natl Acad Sci U S A. 2012;109(13):4762-7 - PMID: 22411831 - PMCID: PMC3324005 - DOI: 10.1073/pnas.1113466109
Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, Macdougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
Proc Natl Acad Sci U S A. 2012;109(52):21444-9 - PMID: 23236189 - PMCID: PMC3535589 - DOI: 10.1073/pnas.1217972110
Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M
Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.
Proc Natl Acad Sci U S A. 2012;109(27):E1868-77 - PMID: 22699504 - PMCID: PMC3390871 - DOI: 10.1073/pnas.1116889109
Santo L, Hideshima T, Kung AL, Tseng JC, Tamang D, Yang M, Jarpe M, van Duzer JH, Mazitschek R, Ogier WC, Cirstea D, Rodig S, Eda H, Scullen T, Canavese M, Bradner J, Anderson KC, Jones SS, Raje N
Preclinical activity, pharmacodynamic and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma.
Blood. 2012;119(11):2579-89 - PMID: 22262760 - PMCID: PMC3337713 - DOI: 10.1182/blood-2011-10-387365
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Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features.
Blood. 2012;119(24):5782-94 - PMID: 22394600 - PMCID: PMC3382938 - DOI: 10.1182/blood-2011-09-380410
Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA
Aquaporin 2 Promotes Cell Migration and Epithelial Morphogenesis.
J Am Soc Nephrol. 2012;23(9):1506-17 - PMID: 22859853 - PMCID: PMC3431417 - DOI: 10.1681/ASN.2012010079
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Mechanisms of Anemia in CKD.
J Am Soc Nephrol. 2012;23(10):1631-4 - PMID: 22935483 - PMCID: PMC3458456 - DOI: 10.1681/ASN.2011111078
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Molecular Mechanisms of Acid-Base Sensing by the Kidney.
J Am Soc Nephrol. 2012;23(5):774-80 - PMID: 22362904 - PMCID: PMC3338302 - DOI: 10.1681/ASN.2012010029
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Hypercholesterolemia links hematopoiesis with atherosclerosis.
Trends Endocrin Met. 2012;24(3):129-136 - PMID: 23228326 - PMCID: PMC4302393 - DOI: 10.1016/j.tem.2012.10.008
Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H
Magnetic Nanoparticles and microNMR for Diagnostic Applications.
Theranostics. 2012;2(1):55-65 - PMID: 22272219 - PMCID: PMC3263516 - DOI: 10.7150/thno.3465
Earley S, Vinegoni C, Dunham J, Gorbatov R, Fumene Feruglio P, Weissleder R
In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single cell resolution.
Cancer Res. 2012;72(12):2949-56 - PMID: 22505651 - PMCID: PMC3603290 - DOI: 10.1158/0008-5472.CAN-11-4096
Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA,
A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force.
Cancer Res. 2012;72(24):6319-6324 - PMID: 23188507 - DOI: 10.1158/0008-5472.CAN-12-3658
Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H
Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity.
PLoS Genet. 2012;8(7):e1002774 - PMID: 22844243 - PMCID: PMC3405999 - DOI: 10.1371/journal.pgen.1002774
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Corin: a key protein of an adaptive renal mechanism to respond to salt variation?
Kidney Int. 2012;82(1):7-8 - PMID: 22699378 - DOI: 10.1038/ki.2012.123
Agasti SS, Kohler RH, Liong M, Peterson VM, Lee H, Weissleder R
Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking.
Small. 2012;9(2):222-7 - PMID: 22996932 - PMCID: PMC3552149 - DOI: 10.1002/smll.201201007
Hennings JC, Picard N, Huebner AK, Stauber T, Maier H, Brown D, Jentsch TJ, Vargas-Poussou R, Eladari D, Hübner CA
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule.
EMBO Mol Med. 2012;4(10):1057-71 - PMID: 22933323 - PMCID: PMC3491836 - DOI: 10.1002/emmm.201201527
Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG
Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics.
Biomaterials . 2012;33(20):5004-12 - PMID: 22494889 - PMCID: PMC3366278 - DOI: 10.1016/j.biomaterials.2012.03.065
Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, Aalberse R, Azumi A, Bloch DB, Brugge WR, Carruthers MN, Cheuk W, Cornell L, Castillo CF, Ferry JA, Forcione D, Klöppel G, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Masaki Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani D, Sato Y, Smyrk T, Stone JR, Takahira M, Umehara H, Webster G, Yamamoto M, Yi E, Yoshino T, Zamboni G, Zen Y, Chari S
IgG4-Related disease: recommendations for the nomenclature of this condition and its individual organ system manifestations.
Arthritis Rheum. 2012;64(10):3061-7 - PMID: 22736240 - DOI: 10.1002/art.34593
Mak AB, Nixon AM, Kittanakom S, Stewart JM, Chen GI, Curak J, Gingras AC, Mazitschek R, Neel BG, Stagljar I, Moffat J
Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation.
Cell Rep. 2012;2(4):951-63 - PMID: 23084749 - PMCID: PMC3590846 - DOI: 10.1016/j.celrep.2012.09.016
Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W
Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure.
Cell Rep. 2012;2(1):52-61 - PMID: 22840396 - PMCID: PMC3627357 - DOI: 10.1016/j.celrep.2012.06.002
Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, Romero P, Wurdinger T, Xavier RJ, Geissmann F, Meylan E, Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ
Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb
Cell Rep. 2012;1(4):1-8 - PMID: 22545247 - PMCID: PMC3334310 - DOI: 10.1016/j.celrep.2012.02.009
Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Mol Ther Nucleic Acids. 2012;1:e4 - PMID: 23344621 - PMCID: PMC3381593 - DOI: 10.1038/mtna.2011.3
Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL
Bevacizumab With Angiostatin-armed oHSV Increases Antiangiogenesis and Decreases Bevacizumab-induced Invasion in U87 Glioma.
Mol Ther. 2012;20(1):37-45 - PMID: 21915104 - PMCID: PMC3255598 - DOI: 10.1038/mt.2011.187
Sosnovik DE, Nahrendorf M, Caravan P
Science to Practice: How Will Myocardial Inflammation Be Imaged with MR Imaging?
Radiology. 2012;264(2):309-11 - PMID: 22821689 - DOI: 10.1148/radiol.12121094
Su HS, Nahrendorf M, Panizzi PR, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW
Vasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase.
Radiology. 2012;262(1):181-90 - PMID: 22084204 - PMCID: PMC3244672 - DOI: 10.1148/radiol.11110040
Forghani R, Wojtkiewicz GR, Zhang Y, Seeburg D, Bautz BR, Pulli B, Milewski AR, Atkinson WL, Iwamoto Y, Zhang ER, Etzrodt M, Rodriguez E, Robbins CS, Swirski FK, Weissleder R, Chen JW
Demyelinating Diseases: Myeloperoxidase as an Imaging Biomarker and Therapeutic Target.
Radiology. 2012;263(2):451-60 - PMID: 22438365 - PMCID: PMC3329272 - DOI: 10.1148/radiol.12111593
Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA
Inflammation Modulates Murine Venous Thrombosis Resolution In Vivo: Assessment by Multimodal Fluorescence Molecular Imaging.
Arterioscler Thromb Vasc Biol. 2012;32(11):2616-24 - PMID: 22995524 - PMCID: PMC3516622 - DOI: 10.1161/ATVBAHA.112.251983
Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH
Consensus statement on the pathology of IgG4-related disease.
Mod Pathol. 2012;25(9):1181-92 - PMID: 22596100 - DOI: 10.1038/modpathol.2012.72
Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA
Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390 - DOI: 10.1016/j.jcmg.2012.01.017
Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M
Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway.
JACC Cardiovasc Imaging. 2012;5(11):1127-38 - PMID: 23153913 - PMCID: PMC3502014 - DOI: 10.1016/j.jcmg.2012.01.025
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY
On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics.
Lab Chip. 2012;12(17):3103-10 - PMID: 22760641 - PMCID: PMC3411869 - DOI: 10.1039/c2lc40337d
Chen W, Sun CC, Chen S, Meynard D, Babitt JL, Lin HY
A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.
Haematologica. 2012;98(2):296-304 - PMID: 22875629 - PMCID: PMC3561439 - DOI: 10.3324/haematol.2012.070136
Chung J*, Shao H*, Reiner T, Issadore D, Weissleder R, Lee H
Cell Sorting: Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells
Adv Healthc Mater. 2012;1(4):432-6 - PMID: 23184773 - PMCID: PMC3508764 - DOI: 10.1002/adhm.201200046 - Cover
Sosnovik DE, Nahrendorf M
Cells and Iron Oxide Nanoparticles on the Move: Magnetic Resonance Imaging of Monocyte Homing and Myocardial Inflammation in Patients With ST-Elevation Myocardial Infarction.
Circ Cardiovasc Imaging. 2012;5(5):551-4 - PMID: 22991284 - PMCID: PMC3529959 - DOI: 10.1161/CIRCIMAGING.112.978932
Majmudar MD, Nahrendorf M
Cardiovascular Molecular Imaging: The Road Ahead.
J Nucl Med. 2012;53(5):673-676 - PMID: 22492729 - PMCID: PMC3744821 - DOI: 10.2967/jnumed.111.099838
Mekkaoui C, Huang S, Chen HH, Dai G, Reese TG, Kostis WJ, Thiagalingam A, Maurovich-Horvat P, Ruskin JN, Hoffmann U, Jackowski MP, Sosnovik DE
Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation.
J Cardiovasc Magn Reson. 2012;14(1):70 - PMID: 23061749 - PMCID: PMC3506570 - DOI: 10.1186/1532-429X-14-70
Wittenberg NJ, Im H, Xu X, Wootla B, Watzlawik J, Warrington AE, Rodriguez M, Oh SH
High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance.
Anal Chem. 2012;84(14):6031-9 - PMID: 22762372 - PMCID: PMC3417152 - DOI: 10.1021/ac300819a
Im H, Sutherland JN, Maynard JA, Oh SH
Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics.
Anal Chem. 2012;84(4):1941-7 - PMID: 22235895 - PMCID: PMC3307221 - DOI: 10.1021/ac300070t
Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R
Sensitive and Direct Detection of Circulating Tumor Cells by Multimarker µ-Nuclear Magnetic Resonance.
Neoplasia. 2012;14(5):388-95 - PMID: 22745585 - PMCID: PMC3384426
Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R
Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents
Neoplasia. 2012;14(3):169-177 - PMID: 22496617 - PMCID: PMC3323895 - Cover
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S
Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity.
ACS Chem Biol. 2012;7(9):1520-8 - PMID: 22724584 - DOI: 10.1021/cb300235m
McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, Botnaru I, Lin CP, Reed GL, Weissleder R, Jaffer FA
Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy.
Nanomedicine (Lond). 2012;7(7):1017-28 - PMID: 22348271 - PMCID: PMC3360120 - DOI: 10.2217/nnm.11.179
Unizony S, Stone JH, Stone JR
New treatment strategies in large-vessel vasculitis.
Curr Opin Rheumatol. 2012;25(1):3-9 - PMID: 23114585 - DOI: 10.1097/BOR.0b013e32835b133a
Nahrendorf M
Macrophages in the infarct: fiery friends or friendly fire?
J Mol Cell Cardiol. 2012;53(5):591-2 - PMID: 22975014 - DOI: 10.1016/j.yjmcc.2012.09.001
Hilgendorf I, Swirski FK
Folate receptor: a macrophage "achilles' heel"?
J Am Heart Assoc. 2012;1(4):e004036 - PMID: 23130179 - PMCID: PMC3487350 - DOI: 10.1161/JAHA.112.004036
Byun H, Hillman TR, Higgins JM, Diez-Silva M, Peng Z, Dao M, Dasari RR, Suresh S, Park Y
Optical measurement of biomechanical properties of individual erythrocytes from a sickle cell patient.
Acta Biomater. 2012;8(11):4130-8 - PMID: 22820310 - PMCID: PMC3576574 - DOI: 10.1016/j.actbio.2012.07.011
van der Laan AM, Nahrendorf M, Piek JJ
Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response.
Heart. 2012;98(18):1384-90 - PMID: 22904145 - DOI: 10.1136/heartjnl-2012-301623
Ueno T, Yeung MY, McGrath M, Yang S, Zaman N, Snawder B, Padera RF, Magee CN, Gorbatov R, Hashiguchi M, Azuma M, Freeman GJ, Sayegh MH, Najafian N
Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses.
Eur J Immunol. 2012;42(9):2343-53 - PMID: 22733595 - PMCID: PMC3822046 - DOI: 10.1002/eji.201242501 - Cover
Miller M, Hafner M, Sontag E, Davidsohn N, Subramanian S, Purnick PE, Lauffenburger D, Weiss R
Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity.
PLoS Comput Biol. 2012;8(7):e1002579 - PMID: 22829755 - PMCID: PMC3400602 - DOI: 10.1371/journal.pcbi.1002579
Lu X, Agasti SS, Vinegoni C, Waterman P, Depinho R, Weissleder R
Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators.
Bioconjug Chem. 2012;23(9):1945-51 - PMID: 22917215 - PMCID: PMC3775343 - DOI: 10.1021/bc300319c
Brueckner C, Ogikubo J, McCarthy JR, Akhigbe J, Hyland MA, Daddario P, Worlinsky JL, Zeller M, Engle JT, Ziegler CJ, Ranaghan MJ, Sandberg MN, Birge RR
meso-Arylporpholactones and their Reduction Products.
J Org Chem. 2012;77(15):6480-94 - PMID: 22734444 - PMCID: PMC3411881 - DOI: 10.1021/jo300963m
Cortez-Retamozo V, Etzrodt M, Pittet MJ
Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors.
J Innate Immunity. 2012;4(5-6):411-23 - PMID: 22433183 - PMCID: PMC3498093 - DOI: 10.1159/000335733
Taqueti VR, Jaffer FA
High-resolution molecular imaging via intravital microscopy: illuminating vascular biology in vivo.
Integr Biol (Camb). 2012;5(2):278-90 - PMID: 23135362 - PMCID: PMC3558556 - DOI: 10.1039/c2ib20194a
Ruan YC, Shum WW, Belleannée C, Da Silva N, Breton S
ATP secretion in the male reproductive tract: essential role of CFTR.
J Physiol. 2012;590(Pt 17):4209-22 - PMID: 22711960 - PMCID: PMC3473280 - DOI: 10.1113/jphysiol.2012.230581
Rao SM, Auger JL, Gaillard P, Weissleder R, Wada E, Torres R, Kojima M, Benoist C, Mathis D, Binstadt BA
The neuropeptide neuromedin U promotes autoantibody-mediated arthritis.
Arthritis Res Ther. 2012;14(1):R29 - PMID: 22314006 - PMCID: PMC3392824 - DOI: 10.1186/ar3732
Kim JK, Vinarsky V, Wain JC, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH
In vivo imaging of tracheal epithelial cells in mice during airway regeneration.
Am J Respir Cell Mol Biol. 2012;47(6):864-8 - PMID: 22984086 - PMCID: PMC3547097 - DOI: 10.1165/rcmb.2012-0164OC
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ
Crebinostat: A Novel cognitive enhancer that inhibits Histone Deacetylase activity and Modulates Chromatin-mediated Neuroplasticity.
Neuropharmacology. 2012;64(1):81-96 - PMID: 22771460 - PMCID: PMC3447535 - DOI: 10.1016/j.neuropharm.2012.06.043
Krapf D, Chun Ruan Y, Wertheimer EV, Battistone MA, Pawlak JB, Sanjay A, Pilder SH, Cuasnicu P, Breton S, Visconti PE
cSrc is necessary for epididymal development and is incorporated into sperm during epididymal transit.
Dev Biol. 2012;369(1):43-53 - PMID: 22750823 - PMCID: PMC3424100 - DOI: 10.1016/j.ydbio.2012.06.017
Unizony S, Arias-Urdaneta L, Miloslavsky E, Arvikar S, Khosroshahi A, Keroack B, Stone J, Stone J
Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, takayasu arteritis) and polymyalgia rheumatica.
Arthritis Care Res (Hoboken). 2012;64(11):1720-9 - PMID: 22674883 - DOI: 10.1002/acr.21750
Wu X, Yung LM, Cheng WH, Yu PB, Babitt JL, Lin HY, Xia Y
Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent.
PLoS ONE. 2012;7(9):e44622 - PMID: 23028567 - PMCID: PMC3441567 - DOI: 10.1371/journal.pone.0044622
Miller MA, Feng XJ, Li G, Rabitz HA
Identifying biological network structure, predicting network behavior, and classifying network state with High Dimensional Model Representation (HDMR).
PLoS ONE. 2012;7(6):e37664 - PMID: 22723838 - PMCID: PMC3377689 - DOI: 10.1371/journal.pone.0037664
Păunescu TG, Rodriguez S, Benz E, McKee M, Tyszkowski R, Albers MW, Brown D
Loss of the V-ATPase B1 Subunit Isoform Expressed in Non-Neuronal Cells of the Mouse Olfactory Epithelium Impairs Olfactory Function.
PLoS ONE. 2012;7(9):e45395 - PMID: 23028982 - PMCID: PMC3447883 - DOI: 10.1371/journal.pone.0045395
Wu Q, Sun CC, Lin HY, Babitt JL
Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs).
PLoS ONE. 2012;7(9):e46307 - PMID: 23029472 - PMCID: PMC3459908 - DOI: 10.1371/journal.pone.0046307
Atkinson W*, Forghani R*, Wojtkiewicz GR, Pulli B, Iwamoto Y, Ueno T, Waterman P, Truelove J, Oklu R, Chen JW
Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice
PLoS ONE. 2012;7(3):e33671 - PMID: 22457780 - PMCID: PMC3310075 - DOI: 10.1371/journal.pone.0033671
Staropoli JF, Haliw L, Biswas S, Garrett L, Hölter SM, Becker L, Skosyrski S, Da Silva-Buttkus P, Calzada-Wack J, Neff F, Rathkolb B, Rozman J, Schrewe A, Adler T, Puk O, Sun M, Favor J, Racz I, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Wolf E, Wurst W, Zimmer A, Lopez E, Harati H, Hill E, Krause DS, Guide J, Dragileva E, Gale E, Wheeler VC, Boustany RM, Brown DE, Breton S, Ruether K, Gailus-Durner V, Fuchs H, de Angelis MH, Cotman SL
Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System.
PLoS ONE. 2012;7(6):e38310 - PMID: 22701626 - PMCID: PMC3368842 - DOI: 10.1371/journal.pone.0038310
Vinegoni C, Feruglio PF, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R
Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography.
PLoS ONE. 2012;7(4):e34427 - PMID: 22509302 - PMCID: PMC3324534 - DOI: 10.1371/journal.pone.0034427
Chong NW, Koekemoer AL, Ounzain S, Samani NJ, Shin JT, Shaw SY
STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway.
PLoS ONE. 2012;7(7):e40966 - PMID: 22815879 - PMCID: PMC3399798 - DOI: 10.1371/journal.pone.0040966
Rice WL, Zhang Y, Chen Y, Matsuzaki T, Brown D, Lu HA
Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells.
PLoS ONE. 2012;7(2):e32843 - PMID: 22403603 - PMCID: PMC3293519 - DOI: 10.1371/journal.pone.0032843
Brown D, Bouley R, Paunescu TG, Breton S, Lu HA
New insights into the dynamic regulation of water and acid/base balance by renal epithelial cells.
Am J Physiol Cell Physiol. 2012;302(10):C1421-33 - PMID: 22460710 - PMCID: PMC3362000 - DOI: 10.1152/ajpcell.00085.2012
Yui N, Lu HA, Chen Y, Nomura N, Bouley R, Brown D
Basolateral targeting and microtubule dependent transcytosis of the aquaporin-2 water channel.
Am J Physiol Cell Physiol. 2012;304(1):C38-48 - PMID: 23015545 - PMCID: PMC3543574 - DOI: 10.1152/ajpcell.00109.2012
Vedovelli L, Rothermel JT, Finberg KE, Wagner CA, Azroyan A, Hill E, Breton S, Brown D, Paunescu TG
Altered V-ATPase expression in renal intercalated cells isolated from B1-subunit deficient mice by fluorescence activated cell sorting.
Am J Physiol Renal Physiol. 2012;304(5):F522-32 - PMID: 23269648 - PMCID: PMC3602708 - DOI: 10.1152/ajprenal.00394.2012
Bouley R, Nunes P, Andriopoulos B, McLaughlin MM, Webber MJ, Lin HY, Babitt JL, Gardella TJ, Ausiello DA, Brown D
Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.
Am J Physiol Renal Physiol. 2012;304(5):F553-64 - PMID: 23235478 - PMCID: PMC3602717 - DOI: 10.1152/ajprenal.00438.2011
Heidt T, Nahrendorf M
Multimodal iron oxide nanoparticles for hybrid biomedical imaging.
NMR Biomed. 2012;26(7):756-65 - PMID: 23065771 - PMCID: PMC3549036 - DOI: 10.1002/nbm.2872
Wang K, Liu TM, Wu J, Horton NG, Lin CP, Xu C
Three-color femtosecond source for simultaneous excitation of three fluorescent proteins in two-photon fluorescence microscopy.
Biomed Opt Express. 2012;3(9):1972-7 - PMID: 23024893 - PMCID: PMC3447541 - DOI: 10.1364/BOE.3.001972
Waters JD, Sanchez C, Sahin A, Futalan D, Gonda DD, Scheer JK, Akers J, Palanichamy K, Waterman P, Chakravarti A, Weissleder R, Morse B, Marsh N, Furfine E, Chen CC, Carvajal I, Carter BS
CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
J Neurooncol. 2012;110(1):37-48 - PMID: 22875706 - PMCID: PMC4291475 - DOI: 10.1007/s11060-012-0948-7
Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R
Noise suppressed, multifocus image fusion for enhanced intraoperative navigation.
J Biophotonics. 2012;6(4):363-70 - PMID: 22887724 - PMCID: PMC3779878 - DOI: 10.1002/jbio.201200086
Derbyshire ER, Mazitschek R, Clardy J
Characterization of Plasmodium Liver Stage Inhibition by Halofuginone.
ChemMedChem. 2012;7(5):844-9 - PMID: 22438279 - PMCID: PMC3359061 - DOI: 10.1002/cmdc.201200045 - Cover
Hilgendorf I, Swirski FK
Making a Difference: Monocyte Heterogeneity in Cardiovascular Disease.
Curr Atheroscler Rep. 2012;14(5):450-9 - PMID: 22847772 - PMCID: PMC3436972 - DOI: 10.1007/s11883-012-0274-8
Duigenan S, Gee MS
Imaging of pediatric patients with inflammatory bowel disease.
AJR Am J Roentgenol. 2012;199(4):907-15 - PMID: 22997386 - DOI: 10.2214/AJR.11.7966
Elmi A, Tabatabaei S, Talab SS, Hedgire SS, Cao K, Harisinghani M
Incidental findings at initial imaging workup of patients with prostate cancer: clinical significance and outcomes.
AJR Am J Roentgenol. 2012;199(6):1305-11 - PMID: 23169722 - DOI: 10.2214/AJR.11.8417
Robbins CS, Swirski FK
Newly discovered innate response activator B cells: crucial responders against microbial sepsis.
Expert Rev Clin Immunol. 2012;8(5):405-7 - PMID: 22882214 - DOI: 10.1586/eci.12.32
Kim Y, Higgins JM, Dasari RR, Suresh S, Park Y
Anisotropic light scattering of individual sickle red blood cells.
J Biomed Opt. 2012;17(4):040501 - PMID: 22559667 - PMCID: PMC3602817 - DOI: 10.1117/1.JBO.17.4.040501
Zettergren E, Vickers D, Runnels J, Murthy SK, Lin CP, Niedre M
Instrument for fluorescence sensing of circulating cells with diffuse light in mice in vivo.
J Biomed Opt. 2012;17(3):037001 - PMID: 22502573 - PMCID: PMC3380949 - DOI: 10.1117/1.JBO.17.3.037001
Lee S, Vinegoni C, Feruglio PF, Weissleder R
Improved intravital microscopy via synchronization of respiration and holder stabilization.
J Biomed Opt. 2012;17(9):96018-1 - PMID: 23085919 - PMCID: PMC3449295 - DOI: 10.1117/1.JBO.17.9.096018
Liu X, Nielsen GP, Rosenberg AE, Waterman PR, Yang W, Choy E, Sassi S, Yang S, Harmon DC, Yang C, Schwab JH, Kobayashi E, Mankin HJ, Xavier R, Weissleder R, Duan Z, Hornicek FJ
Establishment and characterization of a novel chordoma cell line: CH22.
J Orthop Res. 2012;30(10):1666-73 - PMID: 22504929 - DOI: 10.1002/jor.22113
Saxena A, Kessinger CW, Thompson B, McCarthy JR, Iwamoto Y, Lin CP, Jaffer FA
High-Resolution Optical Mapping of Inflammatory Macrophages Following Endovascular Arterial Injury.
Mol Imaging Biol. 2012;15(3):282-9 - PMID: 23090852 - PMCID: PMC3650124 - DOI: 10.1007/s11307-012-0599-2
Lin HY
Transforming Growth Factor-β and the Kidney Revisited: Introduction.
Semin Nephrol. 2012;32(3):225-7 - PMID: 22835452 - DOI: 10.1016/j.semnephrol.2012.04.010
Sahani DV, Bonaffini PA, Catalano OA, Guimaraes AR, Blake MA
State-of-the-Art PET/CT of the Pancreas: Current Role and Emerging Indications.
Radiographics. 2012;32(4):1133-58 - PMID: 22786999 - DOI: 10.1148/rg.324115143
Zettergren E, Swamy T, Runnels J, Lin CP, Niedre M
Tomographic sensing and localization of fluorescently labeled circulating cells in mice in vivo.
Phys Med Biol. 2012;57(14):4627-41 - PMID: 22750660 - PMCID: PMC3555500 - DOI: 10.1088/0031-9155/57/14/4627
Razansky D, Deliolanis N, Vinegoni C, Ntziachristos V
Deep Tissue Optical and Optoacoustic Molecular Imaging Technologies for Small Animal Research and Drug Discovery.
Curr Pharm Biotechnol. 2012;13(4):504-22 - PMID: 22216767
Gutiérrez OM, Sun CC, Chen W, Babitt JL, Lin HY
Statement of Concern about a Commercial Assay Used to Measure Soluble Hemojuvelin in Humans.
Am J Nephrol. 2012;36(4):332-333 - PMID: 23006450 - DOI: 10.1159/000342519
Siddiquee Z, Zane NA, Smith RN, Stone JR
Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease.
Cardiovasc Pathol. 2012;21(6):470-5 - PMID: 22406174 - DOI: 10.1016/j.carpath.2012.02.001
Erdem SS, Sazonova IY, Hara T, Jaffer FA, McCarthy JR
Detection and treatment of intravascular thrombi with magnetofluorescent nanoparticles.
Method Enzymol. 2012;508:191-209 - PMID: 22449927 - DOI: 10.1016/B978-0-12-391860-4.00010-0
McDermott S, Hedgire SS, Hahn PF, Mueller PR, Harisinghani MG
Image-Guided Biopsy of Suspicious Lymph Nodes in Patients with Known Primary Malignancies.
J Vasc Interv Radiol. 2012;23(3):371-6 - PMID: 22265244 - DOI: 10.1016/j.jvir.2011.11.028
Hedgire SS, Pargaonkar VK, Elmi A, Harisinghani AM, Harisinghani MG
Pelvic nodal imaging.
Radiol Clin North Am. 2012;50(6):1111-25 - PMID: 23122041 - DOI: 10.1016/j.rcl.2012.08.002
Hartman RI, Chang CY, Wo JY, Eisenberg JD, Hong TS, Harisinghani MG, Gazelle GS, Pandharipande PV
Optimizing Adjuvant Treatment Decisions for Stage T2 Rectal Cancer Based on Mesorectal Node Size: A Decision Analysis.
Acad Radiol. 2012;20(1):79-89 - PMID: 22947271 - PMCID: PMC3525763 - DOI: 10.1016/j.acra.2012.07.010
Dip PV, Saw WG, Roessle M, Marshansky V, Grüber G
Solution structure of subunit a, a (104-363), of the Saccharomyces cerevisiae V-ATPase and the importance of its C-terminus in structure formation.
J Bioenerg Biomembr. 2012;44(3):341-50 - PMID: 22562380 - DOI: 10.1007/s10863-012-9442-3
Dejesus Allison SO, Javitt MC, Glanc P, Andreotti RF, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Mitchell DG, Pandharipande PV, Pannu HK, Podrasky AE, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM
ACR Appropriateness Criteria® Multiple Gestations.
Ultrasound Q. 2012;28(2):149-155 - PMID: 22634795 - DOI: 10.1097/RUQ.0b013e31824bfc06
Fradley MG, Thakuria JV, Collins AB, Moore SA, Stone JR
Direct Tissue Evaluation via Immunofluorescence: in the Diagnosis of Hereditary Transthyretin Cardiac Amyloidosis.
Tex Heart I J. 2012;39(1):71-5 - PMID: 22412233 - PMCID: PMC3298917
Hedgire SS, Elmi A, Nadkarni ND, Cao K, McDermott S, Harisinghani MG
Preoperative evaluation of perinephric fat invasion in patients with renal cell carcinoma: correlation with pathological findings.
Clin Imaging. 2012;37(1):91-6 - PMID: 23206613 - DOI: 10.1016/j.clinimag.2012.03.005
Im H, Wittenberg NJ, Lindquist NC, Oh SH
Atomic layer deposition (ALD): A versatile technique for plasmonics and nanobiotechnology.
J Mater Res. 2012;27(4):663-671 - PMID: 22865951 - PMCID: PMC3410655 - DOI: 10.1557/jmr.2011.434
Hedgire SS, Oei TN, McDermott S, Cao K, Patel M Z, Harisinghani MG
Multiparametric magnetic resonance imaging of prostate cancer.
Indian J Radiol Imaging. 2012;22(3):160-9 - PMID: 23599562 - PMCID: PMC3624737 - DOI: 10.4103/0971-3026.107176
Vinegoni C, Lee S, Gorbatov R, Weissleder R
Motion compensation using a suctioning stabilizer for intravital microscopy
Intravital. 2012;1:115-121 - PMID: 24086796 - PMCID: PMC3786172 - DOI: 10.4161/intv.23017
Alt C, Runnels J, Teo G, Lin C
In vivo tracking of hematopoietic cells in the retina of chimeric mice with a scanning laser ophthalmoscope
Intravital. 2012;1:132-140
Rosenthal A, Jaffer FA, Ntziachristos V
Intravascular multispectral optoacoustic tomography of atherosclerosis: prospects and challenges.
Imaging Med. 2012;4(3):299-310 - PMID: 23144663 - PMCID: PMC3493570 - DOI: 10.2217/iim.12.20
Phillips JA, Mortensen LJ, Ruiz JP, Sridharan R, Kumar S, Torres M, Sharma P, Lin CP, Karp JM, Hauschka PV
Advances in Single-cell Tracking of Mesenchymal Stem Cells (MSCs) During Musculoskeletal Regeneration.
Orthop J Harv Med Sch. 2012;14:22-28 - PMID: 24244929 - PMCID: PMC3824625
Stone JR
Diagnostic Biopsies of the Native Heart.
Surg Pathol Clin. 2012;5(2):401-16 - PMID: 26838110 - DOI: 10.1016/j.path.2012.04.004
Keliher EJ, Reiner T, Thurber GM, Upadhyay R, Weissleder R
Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells.
ChemistryOpen. 2012;1(4):177-183 - PMID: 23997998 - PMCID: PMC3758109 - DOI: 10.1002/open.201200014
Yui N, Lu HJ, Bouley R, Brown D
AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells.
Biol Open. 2012;1(2):101-8 - PMID: 23213402 - PMCID: PMC3507199 - DOI: 10.1242/bio.2011042
Karchmer AW, MacGillivray TE, Healey TT, Stone JR
Case records of the Massachusetts General Hospital. Case 1-2011. A 35-year-old man with fever, bacteremia, and a mass in the left atrium.
New Engl J Med. 2011;364(2):158-66 - PMID: 21226582 - DOI: 10.1056/NEJMcpc1004362
Kaufman DS, Zietman AL, Dahl DM, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 5-2011. A 65-year-old man with hematuria after treatment for prostate cancer.
New Engl J Med. 2011;364(7):667-75 - PMID: 21323545 - DOI: 10.1056/NEJMcpc1005310
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Celso CL, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP
In vivo imaging of T(reg) cells providing immune privilege to the haematopoietic stem-cell niche.
Nature. 2011;474(7350):216-9 - PMID: 21654805 - PMCID: PMC3725645 - DOI: 10.1038/nature10160
Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE
Mapping and analysis of chromatin state dynamics in nine human cell types.
Nature. 2011;473(7345):43-9 - PMID: 21441907 - PMCID: PMC3088773 - DOI: 10.1038/nature09906
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR
Initial genome sequencing and analysis of multiple myeloma.
Nature. 2011;471(7339):467-72 - PMID: 21430775 - PMCID: PMC3560292 - DOI: 10.1038/nature09837
Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M
Therapeutic siRNA silencing in inflammatory monocytes in mice
Nat Biotechnol. 2011;29(11):1005-10 - PMID: 21983520 - PMCID: PMC3212614 - DOI: 10.1038/nbt.1989
Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE
Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells.
Cell. 2011;147(7):1628-39 - PMID: 22196736 - PMCID: PMC3312319 - DOI: 10.1016/j.cell.2011.09.057
Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains.
Cell. 2011;144(4):513-25 - PMID: 21335234 - PMCID: PMC3572774 - DOI: 10.1016/j.cell.2011.01.020
Walhout AJM, Aebersold R, Meyer T, Bork P, Kirschner MW
Systems Biology: What's the Next Challenge?
Cell. 2011;144:6
Pittet MJ, Weissleder R
Intravital imaging.
Cell. 2011;147(5):983-91 - PMID: 22118457 - PMCID: PMC3824153 - DOI: 10.1016/j.cell.2011.11.004
Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM
Cell-surface sensors for real-time probing of cellular environments.
Nat Nanotechnol. 2011;6(8):524-31 - PMID: 21765401 - PMCID: PMC3163485 - DOI: 10.1038/nnano.2011.101
Yoo H, Kim JW, Shishkov M, Namati E, Morse T, Shubochkin R, McCarthy JR, Ntziachristos V, Bouma BE, Jaffer FA, Tearney GJ
Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo.
Nature Med. 2011;17(12):1680-4 - PMID: 22057345 - PMCID: PMC3233646 - DOI: 10.1038/nm.2555
Panizzi P*, Nahrendorf M*, Jose-Luiz Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation
Nature Med. 2011;17(9):1142-6 - PMID: 21857652 - PMCID: PMC3169740 - DOI: 10.1038/nm.2423
Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A
Reprogramming factor expression initiates widespread targeted chromatin remodeling.
Cell Stem Cell. 2011;8(1):96-105 - PMID: 21211784 - PMCID: PMC3220622 - DOI: 10.1016/j.stem.2010.12.001
Devaraj NK, Weissleder R
Biomedical Applications of Tetrazine Cycloadditions.
Accounts Chem Res. 2011;44(9):816-27 - PMID: 21627112 - PMCID: PMC3166440 - DOI: 10.1021/ar200037t
Tassa C, Shaw SY, Weissleder R
Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy.
Accounts Chem Res. 2011;44(10):842-52 - PMID: 21661727 - PMCID: PMC3182289 - DOI: 10.1021/ar200084x
Santo L, Hideshima T, Kung AL, Yang M, Tamang D, Jarpe M, van Duzer JH, Mazitschek R, Cirstea D, Patel K, Tseng J, Rodig S, Pozzi S, Bradner J, Anderson KC, Jones SS, Raje NS
The effect of selective inhibition of HDAC6 with ACY1215 on bortezomib activity in multiple myeloma (MM).
J Clin Oncol. 2011;29(15_suppl):e18569 - PMID: 28023028
Atri M, Zhang Z, Marques H, Gorelick J, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Gold M,
Utility of preoperative ferumoxtran-10 enhanced MRI to evaluate retroperitoneal lymph node metastasis in advanced cervical cancer: Results of ACRIN 6671/GOG 0233.
J Clin Oncol. 2011;29(15_suppl):5035 - PMID: 28023716
Gold M, Zhang Z, Marques H, Gorelick J, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Atri M
MRI prior to systematic lymphadenectomy in patients with locally advanced cervical cancer.
J Clin Oncol. 2011;29(15_suppl):5042 - PMID: 28023697
Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA
Indocyanine Green Enables Near-Infrared Fluorescence Imaging of Lipid-Rich, Inflamed Atherosclerotic Plaques
Sci Transl Med. 2011;3 (84) ra45):84ra45 - PMID: 21613624 - PMCID: PMC3112179 - DOI: 10.1126/scitranslmed.3001577
Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R.
Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples
Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - DOI: 10.1126/scitranslmed.3002048 - Cover
Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Sci Transl Med. 2011;3(104):104ra101 - PMID: 21998408 - PMCID: PMC3754876 - DOI: 10.1126/scitranslmed.3002191
Shah K
Mesenchymal stem cells engineered for cancer therapy.
Adv Drug Deliv Rev. 2011;64(8):739-48 - PMID: 21740940 - PMCID: PMC3395998 - DOI: 10.1016/j.addr.2011.06.010
Shaw SY, Brettman AD
Phenotyping patient-derived cells for translational studies in cardiovascular disease.
Circulation. 2011;124(22):2444-55 - PMID: 22125190 - PMCID: PMC3263367 - DOI: 10.1161/CIRCULATIONAHA.111.043943
Robbins CS, Chudnovskiy A, Rauch PJ, Figueiredo JL, Iwamoto Y, Gorbatov R, Etzrodt M, Weber GF, Ueno T, van Rooijen N, Mulligan-Kehoe MJ, Libby P, Nahrendorf M, Pittet MJ, Weissleder R, Swirski FK
Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes that Infiltrate Atherosclerotic Lesions.
Circulation. 2011;125(2):364-74 - PMID: 22144566 - PMCID: PMC3263762 - DOI: 10.1161/CIRCULATIONAHA.111.061986
Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R
Report of the national heart, lung, and blood institute working group on the translation of cardiovascular molecular imaging.
Circulation. 2011;123(19):2157-63 - PMID: 21576680 - PMCID: PMC3119488 - DOI: 10.1161/CIRCULATIONAHA.110.000943
Yoon TJ*, Lee H*, Shao H, Hilderbrand SA, Weissleder R
Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles.
Adv Mater. 2011;23(41):4793-7 - PMID: 21953810 - PMCID: PMC3224986 - DOI: 10.1002/adma.201102948
Liong M, Tassa C, Shaw SY, Lee H, Weissleder R
Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization.
Adv Mater. 2011;23(36):H254-7 - PMID: 21780311 - PMCID: PMC3584698 - DOI: 10.1002/adma.201101401
Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V
Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury.
J Am Coll Cardiol. 2011;57(25):2516-26 - PMID: 21679853 - PMCID: PMC3123768 - DOI: 10.1016/j.jacc.2011.02.036
Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R
Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers.
Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171 - DOI: 10.1002/anie.201105670
Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R
Synthesis and In Vivo Imaging of a (18) F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method.
Angew Chem Int Ed Engl. 2011;50(8):1922-5 - PMID: 21328671 - PMCID: PMC3471140 - DOI: 10.1002/anie.201006579
Yoon TJ*, Lee H*, Shao H, Weissleder R
Highly magnetic core-shell nanoparticles with a unique magnetization mechanism.
Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859 - DOI: 10.1002/anie.201100101
Budin G, Yang KS, Reiner T, Weissleder R
Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification.
Angew Chem Int Ed Engl. 2011;50(40):9378-81 - PMID: 21948435 - PMCID: PMC3187564 - DOI: 10.1002/anie.201103273
Karver MR, Weissleder R, Hilderbrand SA
Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging.
Angew Chem Int Ed Engl. 2011;51(4):920-2 - PMID: 22162316 - PMCID: PMC3304098 - DOI: 10.1002/anie.201104389
Ghosh K, Kanapathipillai M, Korin N, McCarthy JR, Ingber D
Polymeric Nanomaterials for Islet Targeting and Immunotherapeutic Delivery.
Nano Lett. 2011;12(1):203-8 - PMID: 22196766 - PMCID: PMC3280082 - DOI: 10.1021/nl203334c
Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE
Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
Gastroenterology. 2011;141(5):1907-14 - PMID: 21745449 - PMCID: PMC3634343 - DOI: 10.1053/j.gastro.2011.06.077
Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R
Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells.
ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118 - DOI: 10.1021/nn203450p
Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R
Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles.
ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727 - DOI: 10.1021/nn2029692
Im H, Lee SH, Wittenberg NJ, Johnson TW, Lindquist NC, Nagpal P, Norris DJ, Oh SH
Template-stripped smooth Ag nanohole arrays with silica shells for surface plasmon resonance biosensing.
ACS Nano. 2011;5(8):6244-53 - PMID: 21770414 - PMCID: PMC3160512 - DOI: 10.1021/nn202013v
Wittenberg NJ, Im H, Johnson TW, Xu X, Warrington AE, Rodriguez M, Oh SH
Facile assembly of micro- and nanoarrays for sensing with natural cell membranes.
ACS Nano. 2011;5(9):7555-64 - PMID: 21842844 - PMCID: PMC3183111 - DOI: 10.1021/nn202554t
Haun J, Devaraj NK, Marinelli B, Lee H, Weissleder R
Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry.
ACS Nano. 2011;5(4):3204-13 - PMID: 21351804 - PMCID: PMC3088084 - DOI: 10.1021/nn200333m
Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, Babitt JL
Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice.
Hepatology. 2011;54(1):273-84 - PMID: 21488083 - PMCID: PMC3277401 - DOI: 10.1002/hep.24359
Leuschner F, Nahrendorf M
Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic.
Circ Res. 2011;108(5):593-606 - PMID: 21372291 - PMCID: PMC3397211 - DOI: 10.1161/CIRCRESAHA.110.232678 - Cover
Brueckner C, Gotz DC, Fox SP, Ryppa C, McCarthy JR, Bruhn T, Akhigbe J, Banerjee S, Daddario P, Daniell HW, Zeller M, Boyle R, Bringmann G
Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins.
J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626 - DOI: 10.1021/ja202451t
Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator.
J Am Chem Soc. 2011;133(27):10368-71 - PMID: 21671557 - PMCID: PMC3165005 - DOI: 10.1021/ja2036628
Shi P, Scott MA, Ghosh B, Wan D, Wissner-Gross Z, Mazitschek R, Haggarty SJ, Yanik MF
Synapse microarray identification of small molecules that enhance synaptogenesis.
Nat Commun. 2011;2:510 - PMID: 22027590 - PMCID: PMC3544154 - DOI: 10.1038/ncomms1518
Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A
IKKb regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.
Nat Commun. 2011;2:318 - PMID: 21587235 - PMCID: PMC3113230 - DOI: 10.1038/ncomms1317
Ladapo JA, Jaffer FA, Weinstein MC, Froelicher ES
Projected Cost-effectiveness of Smoking Cessation Interventions in Patients Hospitalized With Myocardial Infarction.
Arch Intern Med. 2011;171(1):39-45 - PMID: 21220659 - DOI: 10.1001/archinternmed.2010.479
Zhao B, Zou J, Wang H, Johannsen E, Peng CW, Quackenbush J, Mar JC, Morton CC, Freedman ML, Blacklow SC, Aster JC, Bernstein BE, Kieff E
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth.
Proc Natl Acad Sci U S A. 2011;108(36):14902-7 - PMID: 21746931 - PMCID: PMC3169132 - DOI: 10.1073/pnas.1108892108
Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R
Accurate measurement of pancreatic islet {beta}-cell mass using a second-generation fluorescent exendin-4 analog.
Proc Natl Acad Sci U S A. 2011;108(31):12815-20 - PMID: 21768367 - PMCID: PMC3150928 - DOI: 10.1073/pnas.1109859108
Grover WH, Bryan AK, Diez-Silva M, Suresh S, Higgins JM, Manalis SR
Measuring single-cell density.
Proc Natl Acad Sci U S A. 2011;108(27):10992-10996 - PMID: 21690360 - PMCID: PMC3131325 - DOI: 10.1073/pnas.1104651108
Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells.
Proc Natl Acad Sci U S A. 2011;108(36):14908-13 - PMID: 21737748 - PMCID: PMC3169118 - DOI: 10.1073/pnas.1109023108
Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment.
Blood. 2011;119(6):1468-78 - PMID: 22096244 - PMCID: PMC3286211 - DOI: 10.1182/blood-2011-07-368050
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801 - DOI: 10.1182/blood-2011-03-345165
Maiso P, Liu Y, Morgan B, Azab A, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro A, Rommel C, Ghobrial IM
Defining the role of TORC1 and TORC2 in multiple myeloma.
Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208 - DOI: 10.1182/blood-2011-03-342394
Meynard D, Vaja V, Sun CC, Corradini E, Chen S, Lopez-Otin C, Grgurevic L, Hong CC, Stirnberg M, Gutschow M, Vukicevic S, Babitt JL, Lin HY
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.
Blood. 2011;118(3):747-56 - PMID: 21622652 - PMCID: PMC3142910 - DOI: 10.1182/blood-2011-04-348698
Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM
Engineered cell homing.
Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725 - DOI: 10.1182/blood-2010-10-311464
Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats.
Blood. 2011;118(18):4977-84 - PMID: 21730356 - PMCID: PMC3208302 - DOI: 10.1182/blood-2011-03-345066
Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ
Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics.
Cancer Res. 2011;71(13):4608-16 - PMID: 21712408 - PMCID: PMC3129392 - DOI: 10.1158/0008-5472.CAN-11-0412
Ziller MJ, Müller F, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A
Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types.
PLoS Genet. 2011;7(12):e1002389 - PMID: 22174693 - PMCID: PMC3234221 - DOI: 10.1371/journal.pgen.1002389
Babitt JL, Lin HY
The molecular pathogenesis of hereditary hemochromatosis.
Semin Liver Dis. 2011;31(3):280-92 - PMID: 21901658 - DOI: 10.1055/s-0031-1286059
Adli M, Bernstein BE
Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq.
Nat Protoc. 2011;6(10):1656-68 - PMID: 21959244 - PMCID: PMC4493313 - DOI: 10.1038/nprot.2011.402
Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L
PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.
Clin Cancer Res. 2011;17(11):3638-48 - PMID: 21459800 - PMCID: PMC3107920 - DOI: 10.1158/1078-0432.CCR-10-2456
Kleijn A*, Chen JW*, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G
Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.
Clin Cancer Res. 2011;17(13):4484-93 - PMID: 21558403 - PMCID: PMC3131449 - DOI: 10.1158/1078-0432.CCR-11-0575
Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, Macdonald ME, Seong IS
Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Hum Mol Genet. 2011;20(12):2344-55 - PMID: 21447599 - PMCID: PMC3098733 - DOI: 10.1093/hmg/ddr127
Wang H, Smith RN, Spooner AE, Isselbacher EM, Cambria RP, Macgillivray TE, Stone JH, Stone JR
Giant cell aortitis of the ascending aorta without signs or symptoms of systemic vasculitis is associated with elevated risk of distal aortic events.
Arthritis Rheum. 2011;64(1):317-9 - PMID: 21953530 - DOI: 10.1002/art.33343
Helman E, Naxerova K, Kohane IS
DNA hypermethylation in lung cancer is targeted at differentiation-associated genes.
Oncogene. 2011;31(9):1181-8 - PMID: 21804601 - DOI: 10.1038/onc.2011.307
Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA
The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling.
J Neurosci. 2011;31(50):18391-18400 - PMID: 22171041 - PMCID: PMC3243947 - DOI: 10.1523/JNEUROSCI.4550-11.2011
Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ
Genetic and Clinical Correlates of Early Outgrowth Colony Forming Units.
Circ Cardiovasc Genet. 2011;4(3):296-304 - PMID: 21493818 - PMCID: PMC3339257 - DOI: 10.1161/CIRCGENETICS.110.958470
Nahrendorf M, Sosnovik DE
Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging?
Radiology. 2011;260(2):309-10 - PMID: 21778448 - DOI: 10.1148/radiol.11111017
Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R
Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography-Computed Tomography.
Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - DOI: 10.1161/ATVBAHA.110.221499 - Cover
Swirski FK
The spatial and developmental relationships in the macrophage family.
Arterioscler Thromb Vasc Biol. 2011;31(7):1517-22 - PMID: 21677294 - PMCID: PMC3117206 - DOI: 10.1161/ATVBAHA.110.221150
Kim DE, Kim JY, Nahrendorf M, Lee SK, Ryu JH, Kim K, Kwon IC, Schellingerhout D
Direct Thrombus Imaging as a Means to Control the Variability of Mouse Embolic Infarct Models: The Role of Optical Molecular Imaging.
Stroke. 2011;42(12):3566-73 - PMID: 22020025 - DOI: 10.1161/STROKEAHA.111.629428
Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.
Chem Biol. 2011;18(12):1602-10 - PMID: 22195562 - PMCID: PMC3474356 - DOI: 10.1016/j.chembiol.2011.09.016
Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P
Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo.
Thromb Haemostasis. 2011;105(5):828-36 - PMID: 21225096 - PMCID: PMC3087830 - DOI: 10.1160/TH10-09-0589
Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H
Miniature magnetic resonance system for point-of-care diagnostics.
Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660 - DOI: 10.1039/c1lc20177h
Nordbeck P, Hiller KH, Fidler F, Warmuth M, Burkard N, Nahrendorf M, Jakob PM, Quick HH, Ertl G, Bauer WR, Ritter O
Feasibility of Contrast Enhanced and Non-Enhanced MRI for Intra- and Postprocedural Lesion Visualization in Interventional Electrophysiology: Animal Studies and Early Delineation of Isthmus Ablation Lesions in Patients with Typical Atrial Flutter.
Circ Cardiovasc Imaging. 2011;4(3):282-94 - PMID: 21415125 - DOI: 10.1161/CIRCIMAGING.110.957670
Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE
Molecular MRI of Acute Necrosis with a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium.
Circ Cardiovasc Imaging. 2011;4(6):729-737 - PMID: 21836081 - PMCID: PMC3370828 - DOI: 10.1161/CIRCIMAGING.111.966374
Nahrendorf M
Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity.
Circ Cardiovasc Imaging. 2011;4(4):351-3 - PMID: 21772011 - PMCID: PMC3141180 - DOI: 10.1161/CIRCIMAGING.111.966671
Niers JM, Chen JW, Weissleder R, Tannous BA
Enhanced in Vivo Imaging of Metabolically Biotinylated Cell Surface Reporters.
Anal Chem. 2011;83(3):994-9 - PMID: 21214190 - PMCID: PMC3059349 - DOI: 10.1021/ac102758m
Hendricks JA, Keliher EJ, Marinelli B, Reiner T, Weissleder R, Mazitschek R
In Vivo PET-imaging of Histone Deacetylases by 18F-Suberoylanilide Hydroxamic Acid (18F-SAHA).
J Med Chem. 2011;54(15):5576-82 - PMID: 21721525 - PMCID: PMC3150598 - DOI: 10.1021/jm200620f
Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, Wu MX
FTY720 Blocks Egress of T Cells in Part by Abrogation of Their Adhesion on the Lymph Node Sinus.
J Immunol. 2011;187(5):2244-51 - PMID: 21788441 - PMCID: PMC3167479 - DOI: 10.4049/jimmunol.1100670
Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY
Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages.
J Immunol. 2011;186(3):1369-76 - PMID: 21187450 - PMCID: PMC3670585 - DOI: 10.4049/jimmunol.1002047
Riella LV*, Ueno T*, Batal I, De Serres SA, Bassil R, Elyaman W, Yagita H, Medina-Pestana JO, Chandraker A, Najafian N
Blockade of notch ligand delta1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation.
J Immunol. 2011;187(9):4629-38 - PMID: 21949024 - PMCID: PMC3197868 - DOI: 10.4049/jimmunol.1004076
de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW
HDAC6 and HSP90 Control The Functions Of Foxp3+ T-Regulatory Cells.
Mol Cell Biol. 2011;31(10):2066-78 - PMID: 21444725 - PMCID: PMC3133361 - DOI: 10.1128/MCB.05155-11
Chen HH, Feng Y, Zhang M, Chao W, Josephson L, Shaw SY, Sosnovik DE
Protective Effect of the Apoptosis-Sensing Nanoparticle AnxCLIO-Cy5.5.
Nanomedicine (Lond). 2011;8(3):291-298 - PMID: 21704591 - PMCID: PMC3319055 - DOI: 10.1016/j.nano.2011.06.012
McCarthy JR, Jaffer FA
The role of nanomedicine in the imaging and therapy of thrombosis.
Nanomedicine (Lond). 2011;6(8):1291-3 - PMID: 22026372 - PMCID: PMC3332076 - DOI: 10.2217/nnm.11.128
Weissleder R, Castro C
Interview: Nanomedicine in oncology: miniaturized means to an enormous end.
Nanomedicine (Lond). 2011;6(9):1495-8 - PMID: 22077461 - DOI: 10.2217/nnm.11.138
Wang L, Trebicka E, Fu Y, Ellenbogen S, Hong CC, Babitt JL, Lin HY, Cherayil BJ
The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease.
Inflamm Bowel Dis. 2011;18(1):112-9 - PMID: 21351217 - PMCID: PMC3139830 - DOI: 10.1002/ibd.21675
Pittet MJ, Swirski FK
Monocytes link atherosclerosis and cancer.
Eur J Immunol. 2011;41(9):2519-22 - PMID: 21952809 - PMCID: PMC3817567 - DOI: 10.1002/eji.201141727
Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Frohlich LF, Bastepe M
Transgenic Overexpression of the Extra-Large Gs{alpha} Variant XL{alpha}s Enhances Gs{alpha}-Mediated Responses in the Mouse Renal Proximal Tubule in Vivo.
Endocrinology. 2011;152(4):1222-33 - PMID: 21303955 - PMCID: PMC3060637 - DOI: 10.1210/en.2010-1034
Chen S, Webber MJ, Vilardaga JP, Khatri A, Brown D, Ausiello DA, Lin HY, Bouley R
Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand.
Endocrinology. 2011;152(10):3893-904 - PMID: 21828182 - PMCID: PMC3176653 - DOI: 10.1210/en.2011-1049
Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW
ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
J Biol Chem. 2011;286(47):40443-51 - PMID: 21956108 - PMCID: PMC3220463 - DOI: 10.1074/jbc.M111.280495
Li Y, Si R, Feng Y, Chen HH, Zou L, Wang E, Zhang M, Warren HS, Sosnovik DE, Chao W
Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4.
J Biol Chem. 2011;286(36):31308-19 - PMID: 21775438 - PMCID: PMC3173057 - DOI: 10.1074/jbc.M111.246124
Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS
A Modular Strategy for the Construction of Radiometallated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels-Alder Click Chemistry.
Bioconjug Chem. 2011;22(10):2048-59 - PMID: 21877749 - PMCID: PMC3197258 - DOI: 10.1021/bc200288d
Karver M, Weissleder R, Hilderbrand SA
Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation.
Bioconjug Chem. 2011;22(11):2263-2270 - PMID: 21950520 - PMCID: PMC3254257 - DOI: 10.1021/bc200295y
Keliher E, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet M, Weissleder R
89Zr Labeled Dextran Nanoparticles Enable in vivo Macrophage Imaging.
Bioconjug Chem. 2011;22(12):2383-9 - PMID: 22035047 - PMCID: PMC3244512 - DOI: 10.1021/bc200405d
Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R
Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance.
Bioconjug Chem. 2011;22(12):2390-4 - PMID: 22043803 - PMCID: PMC3263317 - DOI: 10.1021/bc200490r
Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jimenez-Diaz MB, Magan N, Gomez V, Ferrer S, Santos Marti
Aminoindoles: a Novel Scaffold with Potent Activity against Plasmodium falciparum.
Antimicrob Agents Chemother. 2011;55(6):2612-22 - PMID: 21422215 - PMCID: PMC3101419 - DOI: 10.1128/AAC.01714-10
Kirsch DG, Grimm J, Guimaraes AR, Weissleder R
In response to dr. Garbow and colleagues.
Int J Radiat Oncol Biol Phys. 2011;79(3):959 - PMID: 21281902
Sun CC, Vaja V, Babitt JL, Lin HY
Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation.
Am J Hematol. 2011;87(4):392-400 - PMID: 22290531 - PMCID: PMC3653431 - DOI: 10.1002/ajh.23110
Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA
Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex.
Clin Genet. 2011;82(6):558-63 - PMID: 22035404 - DOI: 10.1111/j.1399-0004.2011.01805.x
Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM
Nanoparticle-based monitoring of cell therapy.
Nanotechnology. 2011;22(49):494001 - PMID: 22101191 - PMCID: PMC3334527 - DOI: 10.1088/0957-4484/22/49/494001
Ueno T, Yamada A, Ito T, Yeung MY, Gorbatov R, Shimizu T, Abdi R, Sayegh MH, Auchincloss H, Najafian N
Role of Nuclear Factor of Activated T Cell (NFAT) Transcription Factors in Skin and Vascularized Cardiac Allograft Rejection.
Transplantation. 2011;92(5):e26-e27 - PMID: 21866037 - DOI: 10.1097/TP.0b013e318228061c
Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG
BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin.
PLoS ONE. 2011;6(1):e14553 - PMID: 21283739 - PMCID: PMC3024971 - DOI: 10.1371/journal.pone.0014553
Thurber GM, Weissleder R
A Systems Approach for Tumor Pharmacokinetics
PLoS ONE. 2011;6(9):e24696 - PMID: 21935441 - PMCID: PMC3173470 - DOI: 10.1371/journal.pone.0024696
Settles M, Etzrodt M, Kosanke K, Schiemann M, Zimmermann A, Meier R, Braren R, Huber A, Rummeny EJ, Weissleder R, Swirski FK, Wildgruber M
Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles.
PLoS ONE. 2011;6(10):e25197 - PMID: 21984904 - PMCID: PMC3184946 - DOI: 10.1371/journal.pone.0025197
Ryan RJ, Nitta M, Borger D, Zukerberg LR, Ferry JA, Harris NL, Iafrate AJ, Bernstein BE, Sohani AR, Le LP
EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas.
PLoS ONE. 2011;6(12):e28585 - PMID: 22194861 - PMCID: PMC3237460 - DOI: 10.1371/journal.pone.0028585
Shum WW, Da Silva N, Belleannee C, McKee M, Brown D, Breton S
Regulation of V-ATPase recycling via a RhoA and ROCKII dependent pathway in epididymal clear cells.
Am J Physiol Cell Physiol. 2011;301(1):C31-43 - PMID: 21411727 - PMCID: PMC3129830 - DOI: 10.1152/ajpcell.00198.2010
Merkulova M, Hurtado-Lorenzo A, Hosokawa H, Zhuang Z, Brown D, Ausiello DA, Marshansky V
Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.
Am J Physiol Cell Physiol. 2011;300(6):C1442-55 - PMID: 21307348 - PMCID: PMC3118619 - DOI: 10.1152/ajpcell.00076.2010
Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP
An optical platform for cell tracking in adult zebrafish.
Cytometry A. 2011;81(2):176-82 - PMID: 22162445 - DOI: 10.1002/cyto.a.21167
Winter C, Kampik NB, Vedovelli L, Rothenberger F, Paunescu TG, Stehberger PA, Brown D, John H, Wagner CA
Aldosterone stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C dependent pathway.
Am J Physiol Cell Physiol. 2011;301(5):C1251-61 - PMID: 21832245 - PMCID: PMC3213922 - DOI: 10.1152/ajpcell.00076.2011
Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP
Cell labeling approaches for fluorescence-based in vivo flow cytometry.
Cytometry A. 2011;79(10):758-65 - PMID: 21905206 - PMCID: PMC3686107 - DOI: 10.1002/cyto.a.21125
Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM
Circulating angiogenic cell populations, vascular function, and arterial stiffness.
Atherosclerosis. 2011;220(1):145-50 - PMID: 22093724 - PMCID: PMC3277804 - DOI: 10.1016/j.atherosclerosis.2011.10.015
Shon SM, Park JH, Nahrendorf M, Schellingerhout D, Kim JY, Kang BT, Jeong SW, Kim EJ, Ryu JH, Kim K, Kwon IC, Lee DK, Lee MM, Kim DE
Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque.
Atherosclerosis. 2011;216(1):67-73 - PMID: 21334624 - DOI: 10.1016/j.atherosclerosis.2011.01.036
Li W, Zhang Y, Bouley R, Chen Y, Matsuzaki T, Nunes P, Hasler U, Brown D, Lu HA
Simvastatin Enhances Aquaporin 2 Surface Expression and Urinary Concentration in Vasopressin Deficient Brattleboro Rats through Modulation of Rho GTPase.
Am J Physiol Renal Physiol. 2011;301(2):F309-18 - PMID: 21511701 - PMCID: PMC3154588 - DOI: 10.1152/ajprenal.00001.2011
Da Silva N, Cortez-Retamozo V, Reinecker HC, Wildgruber M, Hill E, Brown D, Swirski F, Pittet M, Breton S
A dense network of dendritic cells populates the murine epididymis.
Reproduction. 2011;141(5):653-63 - PMID: 21310816 - PMCID: PMC3657760 - DOI: 10.1530/REP-10-0493 - Cover
Shao F, Yuan H, Josephson L, Weissleder R, Hilderbrand SA
Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores.
Dyes Pigm. 2011;90(2):119-122 - PMID: 21475610 - PMCID: PMC3070263 - DOI: 10.1016/j.dyepig.2010.12.008
Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP
Angiotensin II Stimulates H-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts.
Cell Physiol Biochem. 2011;28(3):513-20 - PMID: 22116365 - PMCID: PMC3709473 - DOI: 10.1159/000335112
Rigosi E, Frasnelli E, Vinegoni C, Antolini R, Anfora G, Vallortigara G, Haase A
Searching for anatomical correlates of olfactory lateralization in the honeybee antennal lobes: A morphological and behavioural study.
Behav Brain Res.. 2011;221(1):290-4 - PMID: 21402106 - PMCID: PMC3089663 - DOI: 10.1016/j.bbr.2011.03.015
Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D
In vivo evaluation of demyelination and remyelination in a nerve crush injury model.
Biomed Opt Express. 2011;2(9):2698-2708 - PMID: 22091449 - PMCID: PMC3184878 - DOI: 10.1364/BOE.2.002698
Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V
In vivo tomographic imaging of red-shifted fluorescent proteins.
Biomed Opt Express. 2011;2(4):887-900 - PMID: 21483611 - PMCID: PMC3072128 - DOI: 10.1364/BOE.2.000887
Haase A, Rigosi E, Trona F, Anfora G, Vallortigara G, Antolini R, Vinegoni C
In-vivo two-photon imaging of the honey bee antennal lobe.
Biomed Opt Express. 2011;2(1):131-8 - PMID: 21326643 - PMCID: PMC3028488 - DOI: 10.1364/BOE.1.000131
Carney BJ, Shah K
Migration and fate of therapeutic stem cells in different brain disease models.
Neuroscience. 2011;197:37-47 - PMID: 21946010 - PMCID: PMC3589128 - DOI: 10.1016/j.neuroscience.2011.08.063
Haun JB, Yoon TJ, Lee H, Weissleder R
Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance.
Methods Mol Biol. 2011;726:33-49 - PMID: 21424441 - DOI: 10.1007/978-1-61779-052-2_3
Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R
High-Yielding, Two-Step (18) F Labeling Strategy for (18) F-PARP1 Inhibitors.
ChemMedChem. 2011;6(3):424-7 - PMID: 21360818 - PMCID: PMC3136544 - DOI: 10.1002/cmdc.201000426
Sun N, Yoon TJ, Lee H, Andress W, Weissleder R, Ham D
Palm NMR and 1-Chip NMR
IEEE J Solid-ST Circ. 2011;46(1):342-352
Goergen CJ, Sosnovik DE
From Molecules to Myofibers: Multiscale Imaging of the Myocardium.
J Cardiovasc Transl Res. 2011;4(4):493-503 - PMID: 21643889 - PMCID: PMC3370890 - DOI: 10.1007/s12265-011-9284-0
Gee MS, Nimkin K, Hsu M, Israel EJ, Biller JA, Katz AJ, Mino-Kenudson M, Harisinghani MG
Prospective Evaluation of MR Enterography as the Primary Imaging Modality for Pediatric Crohn Disease Assessment.
AJR Am J Roentgenol. 2011;197(1):224-31 - PMID: 21701034 - PMCID: PMC3711021 - DOI: 10.2214/AJR.10.5970
Cronin CG, Gervais DA, Hahn PF, Arellano R, Guimaraes AR, Mueller PR
Treatment of Deep Intramuscular and Musculoskeletal Abscess: Experience With 99 CT-Guided Percutaneous Catheter Drainage Procedures.
AJR Am J Roentgenol. 2011;196(5):1182-1188 - PMID: 21512090 - DOI: 10.2214/AJR.09.4082
Runnels JM*, Carlson AL*, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JMJ, Azab AK, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP
Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy
J Biomed Opt. 2011;16(1):011006 - PMID: 21280893 - PMCID: PMC3033873 - DOI: 10.1117/1.3520571
Hajjarian Z, Xi J, Jaffer FA, Tearney GJ, Nadkarni SK
Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall.
J Biomed Opt. 2011;16(2):026005 - PMID: 21361689 - PMCID: PMC3056316 - DOI: 10.1117/1.3533322
Imitola J, Cote D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ
Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice.
J Biomed Opt. 2011;16(2):021109 - PMID: 21361672 - PMCID: PMC3061329 - DOI: 10.1117/1.3533312
Lin JR, Wang H, Collins AB, Stone JR
Tongue necrosis and systemic vascular amyloidosis.
Hum Pathol. 2011;42(5):734-737 - PMID: 21236468 - DOI: 10.1016/j.humpath.2010.08.011
Laha M, Panizzi P, Nahrendorf M, Bock PE
Engineering streptokinase for generation of active site-labeled plasminogen analogs.
Anal Biochem. 2011;415(2):105-15 - PMID: 21570944 - PMCID: PMC3114107 - DOI: 10.1016/j.ab.2011.04.025
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Establishment of Cell-Cell Crosstalk in the Epididymis: Control of Luminal Acidification.
J Androl. 2011;32(6):576-86 - PMID: 21441423 - PMCID: PMC3753098 - DOI: 10.2164/jandrol.111.012971
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Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology.
Cardiovasc Pathol. 2011;21(1):2-16 - PMID: 21353600 - DOI: 10.1016/j.carpath.2011.01.001
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2011 Consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology.
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Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells.
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Haase A, Rigosi E, Frasnelli E, Trona F, Tessarolo F, Vinegoni C, Anfora G, Vallortigara G, Antolini R
A multimodal approach for tracing lateralisation along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies.
Eur Biophys J. 2011;40(11):1247-1258 - PMID: 21956452 - PMCID: PMC3366498 - DOI: 10.1007/s00249-011-0748-6
Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R
Intraoperative Near-infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury: Reply.
World J Surg. 2011;35(3):694-5 - PMID: 20645091 - DOI: 10.1007/s00268-010-0728-5
Baron JM, Higgins JM, Dzik WH
A Revised Timeline for the Origin of Plasmodium falciparum as a Human Pathogen.
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Pelvic applications of diffusion magnetic resonance images.
Magn Reson Imaging Clin N Am. 2011;19(1):133-57 - PMID: 21129639 - DOI: 10.1016/j.mric.2010.10.003
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Cardiomyocyte Death: Insights from Molecular and Microstructural Magnetic Resonance Imaging.
Pediatr Cardiol. 2011;32(3):290-6 - PMID: 21298427 - PMCID: PMC3078825 - DOI: 10.1007/s00246-011-9894-y
Malka R, Rom-Kedar V
Bacteria-phagocyte dynamics, axiomatic modelling and mass-action kinetics.
Math Biosci Eng. 2011;8(2):475-502 - PMID: 21631141
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Investigation of the K2 algorithm in learning Bayesian network classifiers
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Recent progress in SERS biosensing.
Phys Chem Chem Phys. 2011;13(24):11551-67 - PMID: 21509385 - PMCID: PMC3156086 - DOI: 10.1039/c0cp01841d
Thomas S, Waterman P, Chen S, Marinelli B, Seaman M, Rodig S, Ross RW, Josephson L, Weissleder R, Kelly KA
Development of Secreted Protein and Acidic and Rich in Cysteine (SPARC) Targeted Nanoparticles for the Prognostic Molecular Imaging of Metastatic Prostate Cancer
J Nanomedic Nanotechnol. 2011;2(4):112 - PMID: 22319675 - PMCID: PMC3273319 - DOI: 10.4172/2157-7439.1000112
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Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683 - DOI: 10.1002/wnan.115
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Advanced cross-sectional imaging techniques for the detection and characterization of renal masses
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Kamberov YG, Kim J, Mazitschek R, Kuo WP, Whitman M
Microarray profiling reveals the Integrated Stress Response is activated by Halofuginone in mammary epithelial cells.
BMC Res Notes. 2011;4(1):381 - PMID: 21974968 - PMCID: PMC3197508 - DOI: 10.1186/1756-0500-4-381
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Validation of a device for fluorescence sensing of rare circulating cells with diffusive light in an optical flow phantom model.
Conf Proc IEEE Eng Med Biol Soc. 2011;2011:486-9 - PMID: 22254354 - PMCID: PMC3555486 - DOI: 10.1109/IEMBS.2011.6090071
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F-FDG PET Imaging of Atherosclerosis-A New Approach to Detect Inflamed, High-Risk Coronary Plaques?
Curr Cardiovasc Imaging Rep. 2011;4(1):1-3 - PMID: 21297872 - PMCID: PMC3032349 - DOI: 10.1007/s12410-010-9054-4
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Case records of the Massachusetts General Hospital. Case 28-2010. A 32-year-old woman, 3 weeks post partum, with substernal chest pain.
New Engl J Med. 2010;363(12):1164-73 - PMID: 20843252 - DOI: 10.1056/NEJMcpc1000966
Stone JH, Papaliodis GN, Dunbar MR, Stone JR
Case 4-2010 -- a 53-year-old man with arthralgias, oral ulcers, vision loss, and vocal-cord paralysis.
New Engl J Med. 2010;362(6):537-46 - PMID: 20147720 - DOI: 10.1056/NEJMcpc0910090
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Case 24-2010.
New Engl J Med. 2010;363(7):664-675 - PMID: 20818858 - DOI: 10.1056/NEJMcpc1004087
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Charting histone modifications and the functional organization of mammalian genomes.
Nat Rev Genet. 2010;12(1):7-18 - PMID: 21116306 - DOI: 10.1038/nrg2905
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Epigenetic memory in induced pluripotent stem cells.
Nature. 2010;467(7313):285-90 - PMID: 20644535 - PMCID: PMC3150836 - DOI: 10.1038/nature09342
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Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.
Nat Biotechnol. 2010;28(10):1097-105 - PMID: 20852635 - PMCID: PMC2955169 - DOI: 10.1038/nbt.1682
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The NIH Roadmap Epigenomics Mapping Consortium.
Nat Biotechnol. 2010;28(10):1045-8 - PMID: 20944595 - PMCID: PMC3607281 - DOI: 10.1038/nbt1010-1045
Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R
The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1alpha.
Cell. 2010;140(2):280-293 - PMID: 20141841 - PMCID: PMC2821045 - DOI: 10.1016/j.cell.2009.12.041
Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R
Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection
Nat Nanotechnol. 2010;5(9):660-5 - PMID: 20676091 - PMCID: PMC2934903 - DOI: 10.1038/nnano.2010.148
Fan Z, Spencer JA, Lu Y, Pitsillides CM, Singh G, Kim P, Yun SH, Toxavidis V, Strom TB, Lin CP, Koulmanda M
In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response.
Nature Med. 2010;16(6):718-22 - PMID: 20495571 - PMCID: PMC2894571 - DOI: 10.1038/nm.2155
Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE
Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network.
Cell Stem Cell. 2010;6(6):591-602 - PMID: 20569696 - PMCID: PMC2897075 - DOI: 10.1016/j.stem.2010.03.016
Adli M, Zhu J, Bernstein BE
Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors.
Nat Methods. 2010;7(8):615-8 - PMID: 20622861 - PMCID: PMC2924612 - DOI: 10.1038/nmeth.1478
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Multifunctional agents for concurrent imaging and therapy in cardiovascular disease.
Adv Drug Deliv Rev. 2010;62(11):1023-30 - PMID: 20654664 - PMCID: PMC2974776 - DOI: 10.1016/j.addr.2010.07.004
Sakhuja R, Suh WM, Jaffer FA, Jang IK
Residual Thrombogenic Substrate After Rupture of a Lipid-Rich Plaque: Possible Mechanism of Acute Stent Thrombosis?
Circulation. 2010;122(22):2349-2350 - PMID: 21147731 - DOI: 10.1161/CIRCULATIONAHA.110.970079
Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M
High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis.
Circulation. 2010;122(17):1707-15 - PMID: 20937980 - PMCID: PMC3003265 - DOI: 10.1161/CIRCULATIONAHA.109.891804
Nahrendorf M, Pittet MJ, Swirski FK
Monocytes: protagonists of infarct inflammation and repair after myocardial infarction.
Circulation. 2010;121(22):2437-45 - PMID: 20530020 - PMCID: PMC2892474 - DOI: 10.1161/CIRCULATIONAHA.109.916346
Cheng S*, Cohen KS*, Shaw SY*, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ
Association of Colony-Forming Units With Coronary Artery and Abdominal Aortic Calcification.
Circulation. 2010;122(12):1176-1182 - PMID: 20823386 - PMCID: PMC3050056 - DOI: 10.1161/CIRCULATIONAHA.109.931279
Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E
Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation.
Eur Heart J. 2010;31(16):1975-84 - PMID: 20601388 - PMCID: PMC2921509 - DOI: 10.1093/eurheartj/ehq237
Condeelis J, Weissleder R
In Vivo Imaging in Cancer.
Cold Spring Harb Perspect Biol. 2010;2(12):a003848 - PMID: 20861158 - PMCID: PMC2982169 - DOI: 10.1101/cshperspect.a003848 - Cover
Liong M, Shao H, Haun JB, Lee H, Weissleder R
Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications.
Adv Mater. 2010;22(45):5168-72 - PMID: 20859943 - PMCID: PMC2993874 - DOI: 10.1002/adma.201002219
Ozsolak F, Goren A, Gymrek MA, Guttman M, Regev A, Bernstein BE, Milos PM
Digital transcriptome profiling from attomole-level RNA samples.
Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755 - DOI: 10.1101/gr.102129.109
Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M
Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.
J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892 - DOI: 10.1016/j.jacc.2009.08.089
Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R
Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells.
Angew Chem Int Ed Engl. 2010;19 (49):2869-2872 - PMID: 20306505 - PMCID: PMC3433403 - DOI: 10.1002/anie.200906120
Im H, Bantz KC, Lindquist NC, Haynes CL, Oh SH
Vertically oriented sub-10-nm plasmonic nanogap arrays.
Nano Lett. 2010;10(6):2231-6 - PMID: 20499849 - DOI: 10.1021/nl1012085
Bradner JE, West N, Grachan ML, Greenberg EF, Haggarty SJ, Warnow T, Mazitschek R
Chemical phylogenetics of histone deacetylases.
Nat Chem Biol. 2010;6(3):238-243 - PMID: 20139990 - PMCID: PMC2822059 - DOI: 10.1038/nchembio.313 - Cover
Parekkadan B, Upadhyay R, Dunham J, Iwamoto Y, Mizoguchi E, Mizoguchi A, Weissleder R, Yarmush ML
Bone Marrow Stromal Cell Transplants Prevent Experimental Enterocolitis and Require Host CD11b+ Splenocytes.
Gastroenterology. 2010;140(3):966-975.e4 - PMID: 20955701 - PMCID: PMC3033974 - DOI: 10.1053/j.gastro.2010.10.013
Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, Chen S, Vukicevic S, Pietrangelo A, Lin HY, Babitt JL
BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice.
Gastroenterology. 2010;139(5):1721-9 - PMID: 20682319 - PMCID: PMC3295242 - DOI: 10.1053/j.gastro.2010.07.044
Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M
Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice.
J Clin Invest. 2010;120(7):2627-34 - PMID: 20577051 - PMCID: PMC2898607 - DOI: 10.1172/JCI42304
Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R
Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients.
J Clin Invest. 2010;121(1):442-5 - PMID: 21123946 - PMCID: PMC3007157 - DOI: 10.1172/JCI44339
Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D
Jarid2 and PRC2, partners in regulating gene expression.
Gene Dev. 2010;24(4):368-80 - PMID: 20123894 - PMCID: PMC2816736 - DOI: 10.1101/gad.1886410
Im H, Lindquist NC, Lesuffleur A, Oh SH
Atomic layer deposition of dielectric overlayers for enhancing the optical properties and chemical stability of plasmonic nanoholes.
ACS Nano. 2010;4(2):947-54 - PMID: 20131870 - DOI: 10.1021/nn901842r
Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A
Quantitative Nanostructure-Activity Relationship Modeling.
ACS Nano. 2010;4(10):5703-12 - PMID: 20857979 - PMCID: PMC2997621 - DOI: 10.1021/nn1013484
Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M
Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction.
Circ Res. 2010;107(11):1364-73 - PMID: 20930148 - PMCID: PMC2992104 - DOI: 10.1161/CIRCRESAHA.110.227454
Rodriguez E, Nilges M, Weissleder R, Chen JW
Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity.
J Am Chem Soc. 2010;132(1):168-77 - PMID: 19968300 - PMCID: PMC2802665 - DOI: 10.1021/ja905274f
Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG
Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition.
J Am Chem Soc. 2010;132(23):7838-9 - PMID: 20481508 - PMCID: PMC2892974 - DOI: 10.1021/ja101677r
Higgins JM, Mahadevan L
Physiological and pathological population dynamics of circulating human red blood cells.
Proc Natl Acad Sci U S A. 2010;107(47):20587-92 - PMID: 21059904 - PMCID: PMC2996693 - DOI: 10.1073/pnas.1012747107
Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, Deangelo DJ, Carr SA, Schreiber SL, Golub TR, Ebert BL
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.
Proc Natl Acad Sci U S A. 2010;107(28):12617-22 - PMID: 20616024 - PMCID: PMC2906581 - DOI: 10.1073/pnas.1006774107
Gao X, Eladari D, Leviel F, Tew BY, Miro-Julia
Deletion of hensin/DMBT1 blocks conversion of {beta}- to {alpha}-intercalated cells and induces distal renal tubular acidosis.
Proc Natl Acad Sci U S A. 2010;107(50):21872-7 - PMID: 21098262 - PMCID: PMC3003085 - DOI: 10.1073/pnas.1010364107
Tsigkou O, Pomerantseva I, Spencer JA, Redondo PA, Hart AR, O'Doherty E, Lin Y, Friedrich CC, Daheron L, Lin CP, Sundback CA, Vacanti JP, Neville C
Regenerative Medicine Special Feature: Engineered vascularized bone grafts.
Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421 - DOI: 10.1073/pnas.0905445107
Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL
Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes.
Proc Natl Acad Sci U S A. 2010;108(2):492-7 - PMID: 21183721 - PMCID: PMC3021060 - DOI: 10.1073/pnas.1016789108
Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R
Hybrid PET-optical imaging using targeted probes
Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879 - DOI: 10.1073/pnas.0915163107
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, Churchill M, Weller E, Munshi N, Seehra JS, Weissleder R, Anderson KC, Scadden DT, Raje N
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
Proc Natl Acad Sci U S A. 2010;107(11):5124-9 - PMID: 20194748 - PMCID: PMC2841922 - DOI: 10.1073/pnas.0911929107
Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Proc Natl Acad Sci U S A. 2010;107(4):1565-70 - PMID: 20080688 - PMCID: PMC2824379 - DOI: 10.1073/pnas.0908682107
Higgins JM, Sloan SR
Response: Other factors may contribute to differences between sickle cell and non-sickle cell patients.
Blood. 2010;115(21):4315-6 - PMID: 20508172
Xia Y, Babitt JL, Bouley R, Zhang Y, Silva ND, Chen S, Zhuang Z, Samad TA, Brenner GJ, Anderson JL, Hong CC, Schneyer AL, Brown D, Lin HY
Dragon Enhances BMP Signaling and Increases Transepithelial Resistance in Kidney Epithelial Cells.
J Am Soc Nephrol. 2010;21(4):666-77 - PMID: 20167703 - PMCID: PMC2844302 - DOI: 10.1681/ASN.2009050511
Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D
Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration.
J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035 - DOI: 10.1681/ASN.2009121267
Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Aleman JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR
The Phosphoinositide 3-Kinase Regulatory Subunit p85{alpha} Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling.
Cancer Res. 2010;70(13):5305-5315 - PMID: 20530665 - PMCID: PMC3204358 - DOI: 10.1158/0008-5472.CAN-09-3399
Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D
Molecular Mechanism of Chemoresistance by Astrocyte Elevated Gene-1.
Cancer Res. 2010;70(8):3249-58 - PMID: 20388796 - PMCID: PMC2855753 - DOI: 10.1158/0008-5472.CAN-09-4009
Bagci-Onder T, Wakimoto H, Anderegg M, Cameron C, Shah K
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell delivered TRAIL in experimental glioma models.
Cancer Res. 2010;71(1):154-63 - PMID: 21084267 - DOI: 10.1158/0008-5472.CAN-10-1601
Mendenhall EM, Koche RP, Truong T, Zhou VW, Issac B, Chi AS, Ku M, Bernstein BE
GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells.
PLoS Genet. 2010;6(12):e1001244 - PMID: 21170310 - PMCID: PMC3000368 - DOI: 10.1371/journal.pgen.1001244
Lo Celso C, Lin CP, Scadden DT
In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow.
Nat Protoc. 2010;6(1):1-14 - PMID: 21212779 - PMCID: PMC3382040 - DOI: 10.1038/nprot.2010.168
Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E
The absence of a clathrin adapter confers unique polarity essential to proximal tubule function.
Kidney Int. 2010;78(4):382-8 - PMID: 20531453 - PMCID: PMC3684398 - DOI: 10.1038/ki.2010.166
Miranda KC, Bond DT, McKee M, Skog J, Paunescu TG, Da Silva N, Brown D, Russo LM
Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease.
Kidney Int. 2010;78(2):191-9 - PMID: 20428099 - PMCID: PMC4451567 - DOI: 10.1038/ki.2010.106
McCarthy JR, Korngold E, Weissleder R, Jaffer FA
A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis.
Small. 2010;6(18):2041-9 - PMID: 20721949 - PMCID: PMC3018665 - DOI: 10.1002/smll.201000596
Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K
Determining Multiple Aspects of Stem Cell-Based Therapies Using Novel Diagnostic and Therapeutic Multifunctional Molecules.
Stem Cells. 2010;28(4):832-41 - PMID: 20127797 - PMCID: PMC3021283 - DOI: 10.1002/stem.313
Martinez-Boubeta C, Balcells L, Cristool R, Sanfeliu C, Rodriguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martinez B
Self-assembled Multifunctional Fe/MgO Nanospheres for Magnetic Resonance Imaging and Hyperthermia.
Nanomedicine. 2010;6(2):362-370 - PMID: 19800988 - DOI: 10.1016/j.nano.2009.09.003
Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA
Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction.
Biomaterials . 2010;32(4):1102-9 - PMID: 21035182 - DOI: 10.1016/j.biomaterials.2010.10.005
van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K
Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors.
Oncogene. 2010;29(22):3185-95 - PMID: 20305695 - PMCID: PMC3390229 - DOI: 10.1038/onc.2010.75
Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P
Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma.
Mol Ther. 2010;18(6):1130-42 - PMID: 20179672 - PMCID: PMC2889737 - DOI: 10.1038/mt.2010.29
Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ
WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud.
Curr Top Dev Biol. 2010;20(22):1993-2002 - PMID: 21055947 - PMCID: PMC2998074 - DOI: 10.1016/j.cub.2010.09.063
McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R
Targeted nanoagents for the detection of cancers.
Mol Oncol. 2010;4(6):511-28 - PMID: 20851695 - PMCID: PMC2981649 - DOI: 10.1016/j.molonc.2010.08.003
Pandharipande PV, Gervais DA, Hartman RI, Harisinghani MG, Feldman AS, Mueller PR, Gazelle GS
Renal Mass Biopsy to Guide Treatment Decisions for Small Incidental Renal Tumors: A Cost-effectiveness Analysis.
Radiology. 2010;256(3):836-46 - PMID: 20720070 - PMCID: PMC2923731 - DOI: 10.1148/radiol.10092013
Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA
Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis. Novel Detection by Dual-Target Fluorescence Molecular Imaging.
Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475 - DOI: 10.1161/ATVBAHA.110.206342
Yamaura K, Boenisch O, Watanabe T, Ueno T, Vanguri V, Yang J, Tanaka K, Guleria I, Borst J, Zhai Y, Kupiec-Weglinski JW, Najafian N
Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells.
Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922 - DOI: 10.1111/j.1600-6143.2010.03089.x
Jurewicz M, Ueno T, Azzi J, Tanaka K, Murayama T, Yang S, Sayegh MH, Niimi M, Abdi R
Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity.
Am J Transplant. 2010;11(2):348-355 - PMID: 21182586 - DOI: 10.1111/j.1600-6143.2010.03360.x
Osborn EA, Jaffer FA
The year in molecular imaging.
JACC Cardiovasc Imaging. 2010;3(11):1181-95 - PMID: 21071007 - PMCID: PMC3057415 - DOI: 10.1016/j.jcmg.2010.09.009
Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R
A Concise Silylamine Approach to 2-Amino-3-hydroxy-indoles with Potent in vivo Antimalaria Activity.
Org Lett. 2010;12(18):3998-4001 - PMID: 20718474 - DOI: 10.1021/ol101566h
Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H
Self-assembled magnetic filter for highly efficient immunomagnetic separation.
Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961 - DOI: 10.1039/c0lc00149j
Kramer CM, Sinusas AJ, Sosnovik DE, French BA, Bengel FM
Multimodality Imaging of Myocardial Injury and Remodeling.
J Nucl Med. 2010;51 Suppl 1:107S-121S - PMID: 20395347 - PMCID: PMC3078824 - DOI: 10.2967/jnumed.109.068221
Libby P, DiCarli M, Weissleder R
The Vascular Biology of Atherosclerosis and Imaging Targets.
J Nucl Med. 2010;51 Suppl 1:33S-37S - PMID: 20395349 - DOI: 10.2967/jnumed.109.069633
Robbins CS, Swirski FK
The multiple roles of monocyte subsets in steady state and inflammation.
Cell Mol Life Sci. 2010;67(16):2685-93 - PMID: 20437077 - DOI: 10.1007/s00018-010-0375-x
Emdad L, Sarkar D, Lee SG, Su ZZ, Yoo BK, Dash R, Yacoub A, Fuller CE, Shah K, Dent P, Bruce JN, Fisher PB
Astrocyte elevated gene-1: a novel target for human glioma therapy.
Mol Cancer Ther. 2010;9(1):79-88 - PMID: 20053777 - PMCID: PMC3165052 - DOI: 10.1158/1535-7163.MCT-09-0752
Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N
TIM-3: a novel regulatory molecule of alloimmune activation.
J Immunol. 2010;185(10):5806-19 - PMID: 20956339 - PMCID: PMC3619947 - DOI: 10.4049/jimmunol.0903435
Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes.
Mol Cell Biol. 2010;31(2):351-64 - PMID: 21059868 - PMCID: PMC3019975 - DOI: 10.1128/MCB.00259-10
Babitt JL, Lin HY
Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD.
Am J Kidney Dis. 2010;55(4):726-41 - PMID: 20189278 - PMCID: PMC2905036 - DOI: 10.1053/j.ajkd.2009.12.030
Gultepe E, Reynoso FJ, Jhaveri A, Kulkarni P, Nagesha D, Ferris C, Harisinghani M, Campbell RB, Sridhar S
Monitoring of magnetic targeting to tumor vasculature through MRI and biodistribution.
Nanomedicine (Lond). 2010;5(8):1173-82 - PMID: 21039195 - DOI: 10.2217/nnm.10.84
Stone JR
Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease.
Curr Opin Rheumatol. 2010;23(1):88-94 - PMID: 21037477 - DOI: 10.1097/BOR.0b013e3283412f7c
Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH
Caveolin-1 Ablation Reduces the Adverse Cardiovascular Effects of N-{omega}-Nitro-L-Arginine Methyl Ester and Angiotensin II.
Endocrinology. 2010;151(3):1236-46 - PMID: 20097717 - PMCID: PMC2840694 - DOI: 10.1210/en.2009-0514
Wiles KG, Panizzi P, Kroh HK, Bock PE
Skizzle is a novel plasminogen and plasmin binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation.
J Biol Chem. 2010;285(27):21153-64 - PMID: 20435890 - PMCID: PMC2898333 - DOI: 10.1074/jbc.M110.107730
Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY
Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles
Bioconjug Chem. 2010;21:14-19 - PMID: 20028085 - PMCID: PMC2902264 - DOI: 10.1021/bc900438a
Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R
Near-Infrared Fluorescent Probe for Imaging of Pancreatic B Cells
Bioconjug Chem. 2010;21:1362-1368 - PMID: 20583828 - PMCID: PMC2912453 - DOI: 10.1021/bc100184w
Merkulova M, Bakulina A, Thaker YR, Gruber G, Marshansky V
Specific motifs of the V-ATPase a2-subunit isoform interact with catalytic and regulatory domains of ARNO.
Biochim Biophys Acta. 2010;1797(8):1398-1409 - PMID: 20153292 - DOI: 10.1016/j.bbabio.2010.02.009
Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T
Imaging Primary Lung Cancers in Mice to Study Radiation Biology.
Int J Radiat Oncol Biol Phys. 2010;76(4):973-977 - PMID: 20206017 - PMCID: PMC2847457 - DOI: 10.1016/j.ijrobp.2009.11.038
Panchenko MP, Siddiquee Z, Dombkowski DM, Alekseyev YO, Lenburg ME, Walker JD, Macgillivray TE, Preffer FI, Stone JR
Protein Kinase CK1{alpha}LS Promotes Vascular Cell Proliferation and Intimal Hyperplasia.
Am J Pathol. 2010;177(3):1562-72 - PMID: 20696773 - PMCID: PMC2928985 - DOI: 10.2353/ajpath.2010.100327
Shi S, Hoogaars WM, de Gorter DJ, van Heiningen SH, Lin HY, Hong CC, Kemaladewi DU, Aartsma-Rus A, Ten Dijke P, 't Hoen PA
BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model.
Neurobiol Dis. 2010;41(2):353-60 - PMID: 20940052 - PMCID: PMC3674857 - DOI: 10.1016/j.nbd.2010.10.003
Setoguchi S, Higgins JM, Mogun H, Mootha VK, Avorn J
Propranolol and the risk of hospitalized myopathy: Translating chemical genomics findings into population-level hypotheses.
Am Heart J. 2010;159(3):428-433 - PMID: 20211305 - DOI: 10.1016/j.ahj.2009.12.008
Miller MA, Barkal L, Jeng K, Herrlich A, Moss M, Griffith LG, Lauffenburger DA
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities.
Integr Biol (Camb). 2010;3(4):422-38 - PMID: 21180771 - PMCID: PMC3173501 - DOI: 10.1039/c0ib00083c
Reiner T, Earley S, Turetsky A, Weissleder R
Bioorthogonal Small-Molecule Ligands for PARP1 Imaging in Living Cells.
Chembiochem. 2010;11(17):2374-2377 - PMID: 20967817 - PMCID: PMC3034378 - DOI: 10.1002/cbic.201000477
Stone JH, Khosroshahi A, Deshpande V, Stone JR
IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases.
Arthritis Care Res. 2010;62(3):316-22 - PMID: 20391477 - DOI: 10.1002/acr.20095
Malka R, Shochat E, Rom-Kedar V
Bistability and bacterial infections.
PLoS ONE. 2010;5(5):e10010 - PMID: 20463954 - PMCID: PMC2864736 - DOI: 10.1371/journal.pone.0010010
Berny MA, Munnix IC, Auger JM, Schols SE, Cosemans JM, Panizzi P, Bock PE, Watson SP, McCarty OJ, Heemskerk JW
Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear.
PLoS ONE. 2010;5(4):e10415 - PMID: 20454680 - PMCID: PMC2861630 - DOI: 10.1371/journal.pone.0010415
Miranda KC, Karet FE, Brown D
An Extended Nomenclature for Mammalian V-ATPase Subunit Genes and Splice Variants.
PLoS ONE. 2010;5(3):e9531 - PMID: 20224822 - PMCID: PMC2835735 - DOI: 10.1371/journal.pone.0009531
Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG
Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models.
PLoS ONE. 2010;5(4):e10032 - PMID: 20386609 - PMCID: PMC2850367 - DOI: 10.1371/journal.pone.0010032
Da Silva N, Pisitkun T, Belleannee C, Miller LR, Nelson RD, Knepper MA, Brown D, Breton S
Proteomic analysis of V-ATPase-rich cells harvested from the kidney and epididymis by fluorescence activated cell sorting.
Am J Physiol Cell Physiol. 2010;298(6):C1326-42 - PMID: 20181927 - PMCID: PMC2889637 - DOI: 10.1152/ajpcell.00552.2009
Belleannee C, Da Silva N, Shum WW, Brown D, Breton S
Role of purinergic signaling pathways in V-ATPase recruitment to the apical membrane of acidifying epididymal clear cells.
Am J Physiol Cell Physiol. 2010;298(4):C817-30 - PMID: 20071692 - PMCID: PMC2853219 - DOI: 10.1152/ajpcell.00460.2009
Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D
Cyclic AMP stimulates apical V-ATPase accumulation, microvillar elongation and proton extrusion in kidney collecting duct A-intercalated cells.
Am J Physiol Renal Physiol. 2010;298(3):F643-54 - PMID: 20053793 - PMCID: PMC2838605 - DOI: 10.1152/ajprenal.00584.2009
Zhuang Z, Marshansky V, Breton S, Brown D
Is caveolin involved in normal proximal tubule (PT) function? Presence in model PT systems but absence in situ.
Am J Physiol Renal Physiol. 2010;300(1):F199-206 - PMID: 20980408 - PMCID: PMC3023221 - DOI: 10.1152/ajprenal.00513.2010
Razansky RN, Rosenthal A, Mallas G, Razansky D, Jaffer FA, Ntziachristos V
Near-infrared fluorescence catheter system for two-dimensional intravascular imaging in vivo.
Opt Express. 2010;18(11):11372-81 - PMID: 20588998
Li C, Pastila RK, Pitsillides C, Runnels JM, Puoris'haag M, Cote D, Lin CP
Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence.
Opt Express. 2010;18(2):988-99 - PMID: 20173920 - PMCID: PMC3369551
Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R
Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography.
Opt Lett. 2010;35(7):1088-90 - PMID: 20364226 - PMCID: PMC2900933
Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN, Reis SA, Klein PS, Mazitschek R, Maglathlin RL, Lewis TA, Haggarty SJ
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
ACS Med Chem Lett. 2010;2(1):39-42 - PMID: 21874153 - PMCID: PMC3161516 - DOI: 10.1021/ml1001954
Jaffer FA
Intravital Fluorescence Microscopic Molecular Imaging of Atherosclerosis.
Methods Mol Biol. 2010;680:131-140 - PMID: 21153378 - PMCID: PMC3051165 - DOI: 10.1007/978-1-60761-901-7_9
Shah K
Imaging Fate of Stem Cells at a Cellular Resolution in the Brains of Mice.
Methods Mol Biol. 2010;680:91-101 - PMID: 21153375 - DOI: 10.1007/978-1-60761-901-7_6
Shah K
In Vivo Imaging of the Dynamics of Different Variants of EGFR in Glioblastomas.
Methods Mol Biol. 2010;680:153-164 - PMID: 21153380 - DOI: 10.1007/978-1-60761-901-7_11
Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M
Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells.
Exp Hematol. 2010;38(4):333-9 - PMID: 20167247 - PMCID: PMC3965294 - DOI: 10.1016/j.exphem.2010.02.003
Estiu G, West N, Mazitschek R, Greenberg E, Bradner JE, Wiest O
On the inhibition of histone deacetylase 8.
Bioorg Med Chem. 2010;18(11):4103-4110 - PMID: 20472442 - PMCID: PMC3245874 - DOI: 10.1016/j.bmc.2010.03.080
Gee MS, Kim JY, Gervais DA, Hahn PF, Mueller PR
Management of abdominal and pelvic abscesses that persist despite satisfactory percutaneous drainage catheter placement.
AJR Am J Roentgenol. 2010;194(3):815-20 - PMID: 20173165 - DOI: 10.2214/AJR.09.3282
Sena BF, Stern JP, Pandharipande PV, Klemm B, Bulman J, Pedrosa I, Rofsky NM
Screening patients to assess renal function before administering gadolinium chelates: assessment of the choyke questionnaire.
AJR Am J Roentgenol. 2010;195(2):424-8 - PMID: 20651199 - DOI: 10.2214/AJR.09.3803
Cronin CG, Harisinghani MG, Catalano O, Blake MA
Multitechnique imaging findings of prolene plug hernia repair.
AJR Am J Roentgenol. 2010;195(3):701-6 - PMID: 20729449 - DOI: 10.2214/AJR.09.4142
Uppot RN, Harisinghani MG, Gervais DA
Imaging-guided percutaneous renal biopsy: rationale and approach.
AJR Am J Roentgenol. 2010;194(6):1443-9 - PMID: 20489082 - DOI: 10.2214/AJR.10.4427
Calfon MA, Vinegoni C, Ntziachristos V, Jaffer FA
Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques.
J Biomed Opt. 2010;15(1):011107 - PMID: 20210433 - PMCID: PMC3188610 - DOI: 10.1117/1.3280282
Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R
MRI with Magnetic Nanoparticles Monitors Downstream Anti-Angiogenic Effects of mTOR Inhibition.
Mol Imaging Biol. 2010;13(2):314-20 - PMID: 20559742 - DOI: 10.1007/s11307-010-0357-2
Thurber GM, Weissleder R
Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels.
Mol Imaging Biol. 2010;13(4):623-32 - PMID: 20809210 - PMCID: PMC3000888 - DOI: 10.1007/s11307-010-0397-7
Merkulova M, McKee M, Dip PV, Gruber G, Marshansky V
N-terminal domain of the V-ATPase a2-subunit displays integral membrane protein properties.
Protein Sci. 2010;19(10):1850-1862 - PMID: 20669186 - PMCID: PMC2998721 - DOI: 10.1002/pro.470
Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R
Block matching 3D random noise filtering for absorption optical projection tomography.
Phys Med Biol. 2010;55(18):5401-5415 - PMID: 20736500 - PMCID: PMC2934766 - DOI: 10.1088/0031-9155/55/18/009
Thurber GM, Figueiredo JL, Weissleder R
Detection limits of intraoperative near infrared imaging for tumor resection.
J Surg Oncol. 2010;102(7):758-64 - PMID: 20872807 - PMCID: PMC3758114 - DOI: 10.1002/jso.21735
Hamilton AM, Rogers KA, Belisle AJ, Ronald JA, Rutt BK, Weissleder R, Boughner DR
Early identification of aortic valve sclerosis using iron oxide enhanced MRI.
J Magn Reson Imaging. 2010;31(1):110-6 - PMID: 20027578 - PMCID: PMC5638659 - DOI: 10.1002/jmri.22008
Islam T, Harisinghani MG
Prostate cancer imaging: what the next decade holds.
Expert Rev Med Devices. 2010;7(5):577-9 - PMID: 20822379 - DOI: 10.1586/erd.10.43
Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH
A novel in vivo regulatory role of P-glycoprotein in alloimmunity.
Biochem Bioph Res Co. 2010;394(3):646-52 - PMID: 20230790 - PMCID: PMC3756468 - DOI: 10.1016/j.bbrc.2010.03.040
Shao H, Yoon TJ, Liong M, Weissleder R, Lee H
Magnetic nanoparticles for biomedical NMR-based diagnostics
Beilstein J Nanotechnol. 2010;1:142154 - PMID: 21977404 - PMCID: PMC3045933 - DOI: 10.3762/bjnano.1.17
Bolondi G, Garuti C, Corradini E, Zoller H, Vogel W, Finkenstedt A, Babitt JL, Lin HY, Pietrangelo A
Altered hepatic BMP signaling pathway in human HFE hemochromatosis.
Blood Cells Mol Dis. 2010;45(4):308-12 - PMID: 20863724 - PMCID: PMC3295241 - DOI: 10.1016/j.bcmd.2010.08.010
Figueiredo JL, Siegel C, Nahrendorf M, Weissleder R
Intraoperative Near-Infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury.
World J Surg. 2010;34 (2):336-343 - PMID: 20033407 - PMCID: PMC2809822 - DOI: 10.1007/s00268-009-0332-8
Iyer VR, Hahn PF, Blaszkowsky LS, Thayer SP, Halpern EF, Harisinghani MG
Added Value of Selected Images Embedded Into Radiology Reports to Referring Clinicians.
J Am Coll Radiol. 2010;7(3):205-210 - PMID: 20193926 - PMCID: PMC3086392 - DOI: 10.1016/j.jacr.2009.10.014
de la Rosette J, Ahmed H, Barentsz J, Johansen TB, Brausi M, Emberton M, Frauscher F, Greene D, Harisinghani M, Haustermans K, Heidenreich A, Kovacs G, Mason M, Montironi R, Mouraviev V, de Reijke T, Taneja S, Thuroff S, Tombal B, Trachtenberg J, Wijkstra H, Polascik T
Focal therapy in prostate cancer-report from a consensus panel.
J Endourol. 2010;24(5):775-80 - PMID: 20477543 - DOI: 10.1089/end.2009.0596
Eisner BH, Kurtz MP, Harisinghani MG
Evolving Role of Magnetic Resonance Imaging in Renal Cancer Imaging.
J Endourol. 2010;24(5):707-11 - PMID: 20433369 - DOI: 10.1089/end.2009.0507
Lee DK, Nahrendorf M, Schellingerhout D, Kim DE
Will molecular optical imaging have clinically important roles in stroke management, and how?
J Clin Neurol. 2010;6(1):10-8 - PMID: 20386638 - PMCID: PMC2851295 - DOI: 10.3988/jcn.2010.6.1.10
Prakash P, Kalra MK, Stone JR, Shepard JA, Digumarthy SR
Imaging findings of pericardial metastasis on chest computed tomography.
J Comput Assist Tomogr. 2010;34(4):554-8 - PMID: 20657224 - DOI: 10.1097/RCT.0b013e3181d77d7e
Sanghvi D, Harisinghani MG
Modalities in modern radiology: A synopsis.
J Postgrad Med. 2010;56(2):85-7 - PMID: 20622386 - DOI: 10.4103/0022-3859.65282
Shenoy-Bhangle A, Nimkin K, Gee MS
Pediatric imaging: Current and emerging techniques.
J Postgrad Med. 2010;56(2):98-102 - PMID: 20622388 - DOI: 10.4103/0022-3859.65273
Karaosmanoglu AD, Gee MS
Sonographic findings of an adrenal leiomyosarcoma.
J Ultrasound Med. 2010;29(9):1369-73 - PMID: 20733196
Libby P, Nahrendorf M, Weissleder R
Molecular imaging of atherosclerosis: a progress report.
Tex Heart I J. 2010;37(3):324-7 - PMID: 20548813 - PMCID: PMC2879214
Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG
Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT.
Clin Imaging. 2010;34(1):20-28 - PMID: 20122515 - DOI: 10.1016/j.clinimag.2009.03.012
Saokar A, Islam T, Jantsch M, Saksena MA, Hahn PF, Harisinghani MG
Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging.
Clin Imaging. 2010;34(5):361-6 - PMID: 20813300 - DOI: 10.1016/j.clinimag.2009.07.004
Saokar A, Gee MS, Islam T, Mueller PR, Harisinghani MG
Appearance of primary lymphoid malignancies on lymphotropic nanoparticle-enhanced magnetic resonance imaging using ferumoxtran-10.
Clin Imaging. 2010;34(6):448-52 - PMID: 21092874 - DOI: 10.1016/j.clinimag.2009.09.008
Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V
Bi-stability of phagocyte-bacteria interaction: when do neutrophils win the battle with Staphylococcus Aureus?
44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy. 2010;:ePub
Huang S, Sosnovik DE
Molecular and Microstructural Imaging of the Myocardium.
Curr Cardiovasc Imaging Rep. 2010;3(1):26-33 - PMID: 20689659 - PMCID: PMC2916196 - DOI: 10.1007/s12410-010-9007-y
Im H, Wittenberg NJ, Lesuffleur A, Lindquist NC, Oh SH
Membrane protein biosensing with plasmonic nanopore arrays and pore-spanning lipid membranes.
Chem Sci. 2010;1(6):688-696 - PMID: 21218136 - PMCID: PMC3015192 - DOI: 10.1039/C0SC00365D
Haun JB, Yoon TJ, Lee H, Weissleder R
Magnetic nanoparticle biosensors.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;2(3):291-304 - PMID: 20336708 - DOI: 10.1002/wnan.84
McCarthy JR
Nanomedicine and Cardiovascular Disease.
Curr Cardiovasc Imaging Rep. 2010;3(1):42-49 - PMID: 20369034 - PMCID: PMC2848940 - DOI: 10.1007/s12410-009-9002-3
Chen HH, Josephson L, Sosnovik DE
Imaging of apoptosis in the heart with nanoparticle technology.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683 - DOI: 10.1002/wnan.115
Kaufman DS, McDougal WS, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 30-2009. A 77-year-old man with recurrent transitional-cell carcinoma of the ureter.
New Engl J Med. 2009;361(13):1292-9 - PMID: 19776411 - DOI: 10.1056/NEJMcpc0900642
Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, C
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH
HDAC2 negatively regulates memory formation and synaptic plasticity.
Nature. 2009;459(7243):55-60 - PMID: 19424149 - PMCID: PMC3498958 - DOI: 10.1038/nature07925
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.
Nature. 2009;458(7235):223-7 - PMID: 19182780 - PMCID: PMC2754849 - DOI: 10.1038/nature07672
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature. 2009;459(7243):103-7 - PMID: 19322176 - PMCID: PMC2761017 - DOI: 10.1038/nature07859
Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Nat Genet. 2009;41(4):482-7 - PMID: 19252486 - PMCID: PMC2810136 - DOI: 10.1038/ng.335
Chi A, Bernstein B
Developmental biology. Pluripotent chromatin state.
Science. 2009;323(5911):220-1 - PMID: 19131621 - PMCID: PMC4126799 - DOI: 10.1126/science.1166261
Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A
Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response.
Science. 2009;324(5932):1334-1338 - PMID: 19498172 - PMCID: PMC2803727 - DOI: 10.1126/science.1172638
Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J
Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
Science. 2009;326(5950):289-93 - PMID: 19815776 - PMCID: PMC2858594 - DOI: 10.1126/science.1181369
Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A
Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses.
Science. 2009;326(5950):257-63 - PMID: 19729616 - PMCID: PMC2879337 - DOI: 10.1126/science.1179050
Swirski* FK, Nahrendorf* M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
Science. 2009;325 (5940):612-6 - PMID: 19644120 - PMCID: PMC2803111 - DOI: 10.1126/science.1175202
Razansky D, Distel M, Vinegoni C, Ma R, Perrimon N, Koster RW, Ntziachristos V
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo
Nat Photonics. 2009;3:412 - 417
Khosroshahi A, Stone JR, Pratt DS, Deshpande V, Stone JH
Painless jaundice with serial multi-organ dysfunction.
Lancet Oncol. 2009;373(9673):1494 - PMID: 19394539 - DOI: 10.1016/S0140-6736(09)60615-2
Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.
Nat Methods. 2009;7(1):47-9 - PMID: 19946276 - PMCID: PMC2862482 - DOI: 10.1038/nmeth.1404
Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB
Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis.
Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995 - DOI: 10.1016/j.molcel.2009.11.002
Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R
Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease.
Circulation. 2009;119(13):1785-94 - PMID: 19307473 - PMCID: PMC2717745 - DOI: 10.1161/CIRCULATIONAHA.108.827972
Christen T*, Nahrendorf M*, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P
Molecular Imaging of Innate Immune Cell Function in Transplant Rejection.
Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889 - DOI: 10.1161/CIRCULATIONAHA.108.796888
Ronald JA*, Chen JW*, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK
Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques.
Circulation. 2009;120(7):592-9 - PMID: 19652086 - PMCID: PMC2736635 - DOI: 10.1161/CIRCULATIONAHA.108.813998
Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Handschumacher MD, Sullivan S, Johnson B, Titus JS, Iwamoto Y, Wylie-Sears J, Levine RA, Carpentier A
Active Adaptation of the Tethered Mitral Valve. Insights Into a Compensatory Mechanism for Functional Mitral Regurgitation.
Circulation. 2009;120(4):334-42 - PMID: 19597052 - PMCID: PMC2752046 - DOI: 10.1161/CIRCULATIONAHA.108.846782
Matter CM, Stuber M, Nahrendorf M
Imaging of the unstable plaque: how far have we got?
Eur Heart J. 2009;30(21):2566-74 - PMID: 19833636 - PMCID: PMC2771148 - DOI: 10.1093/eurheartj/ehp419
Jaffer FA
Assessing niacin as an atherosclerosis therapeutic agent valuable insights provided by high-resolution vascular magnetic resonance imaging.
J Am Coll Cardiol. 2009;54(19):1795-6 - PMID: 19874993 - DOI: 10.1016/j.jacc.2009.07.026
Lee H*, Yoon TJ*, Weissleder R
Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System.
Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069 - DOI: 10.1002/anie.200901791
Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R
Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition.
Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075 - DOI: 10.1002/anie.200903233
Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.
Nat Chem Biol. 2009;5(10):734-42 - PMID: 19701185 - PMCID: PMC3032084 - DOI: 10.1038/nchembio.206
Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B, Lin HY, Pietrangelo A, Babitt JL
Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis.
Gastroenterology. 2009;137(4):1489-97 - PMID: 19591830 - PMCID: PMC2757523 - DOI: 10.1053/j.gastro.2009.06.057
Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ
Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.
J Clin Invest. 2009;119(11):3322-8 - PMID: 19809161 - PMCID: PMC2769199 - DOI: 10.1172/JCI39939
Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA
Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation.
J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134 - DOI: 10.1021/ja903922u
Shaw SY
Molecular imaging in cardiovascular disease: targets and opportunities.
Nat Rev Cardiol. 2009;6(9):569-79 - PMID: 19621013 - DOI: 10.1038/nrcardio.2009.119
Taboada E, Solanas R, Rodriguez E, Weissleder R, Roig A
Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core (γ-Fe2O3)/Shell(SiO2) Nanoparticles as High Relaxivity T2-Contrast Agents for Magnetic Resonance Imaging
Adv Funct Mater. 2009;19 :2319-2324
Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA
Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.
Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449 - DOI: 10.1073/pnas.0902408106
Butcher R, Ragains J, Li W, Ruvkun G, Clardy J, Mak H
Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283 - DOI: 10.1073/pnas.0810338106
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331 - DOI: 10.1073/pnas.0813314106
Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy.
Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771 - DOI: 10.1073/pnas.0806647106
Lee H*, Yoon TJ*, Figueiredo JL, Swirski FK, Weissleder R
Rapid detection and profiling of cancer cells in fine-needle aspirates.
Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371 - DOI: 10.1073/pnas.0902365106
Kroh H, Panizzi P, Bock P
Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin.
Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071 - DOI: 10.1073/pnas.0811750106
Yoo B, Gredler R, Vozhilla N, Su Z, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher P, Sarkar D
Identification of genes conferring resistance to 5-fluorouracil.
Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317 - DOI: 10.1073/pnas.0901451106
Hilderbrand SA, Weissleder R
Near-infrared fluorescence: application to in vivo molecular imaging.
Curr Opin Chem Bio. 2009;14:1-9 - PMID: 19879798 - DOI: 10.1016/j.cbpa.2009.09.029
Azab A, Runnels J, Pitsillides C, Moreau A, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson A, Alt C, Burwick N, Roccaro A, Ngo H, Farag M, Melhem M, Sacco A, Munshi N, Hideshima T, Rollins B, Anderson K, Kung A, Lin CP, Ghobrial I
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Blood. 2009;113:4341-51 - PMID: 19139079 - PMCID: PMC2676090 - DOI: 10.1182/blood-2008-10-186668
Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM
microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922 - DOI: 10.1182/blood-2009-01-198408
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM
Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma.
Blood. 2009;114(3):619-29 - PMID: 19443661 - PMCID: PMC2713475 - DOI: 10.1182/blood-2009-01-199281
Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R
Divergent role of donor dendritic cells in rejection versus tolerance of allografts.
J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678 - DOI: 10.1681/ASN.2008040377
Corradini E, Babitt JL, Lin HY
The RGM/DRAGON family of BMP co-receptors.
Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994 - DOI: 10.1016/j.cytogfr.2009.10.008
Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD
Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors.
Cancer Res. 2009;69(8):3472-81 - PMID: 19351838 - PMCID: PMC2785462 - DOI: 10.1158/0008-5472.CAN-08-3886
McCarthy JR
The future of theranostic nanoagents.
Nanomedicine. 2009;4(7):693-5 - PMID: 19839803 - DOI: 10.2217/nnm.09.58
Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS
The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells.
Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971 - DOI: 10.1016/j.biomaterials.2009.10.019
Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U
Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
Arthritis Rheum. 2009;60:2314-2324 - PMID: 19644878 - PMCID: PMC3080016 - DOI: 10.1002/art.24704
Stone JH, Khosroshahi A, Hilgenberg A, Spooner A, Isselbacher EM, Stone JR
IgG4-related systemic disease and lymphoplasmacytic aortitis.
Arthritis Rheum. 2009;60(10):3139-3145 - PMID: 19790067 - DOI: 10.1002/art.24798
Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R
MRI of a Novel Murine Working Heart Transplant Model
Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535 - DOI: 10.1161/CIRCHEARTFAILURE.109.852707
Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U
Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation.
Radiology. 2009;251(3):813-21 - PMID: 19474377 - PMCID: PMC2687531 - DOI: 10.1148/radiol.2513081450
Sosnovik DE
Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques?
Radiology. 2009;251:309-10 - PMID: 19401565 - DOI: 10.1148/radiol.2512090268
Deguchi JO, Yamazaki H, Aikawa E, Aikawa M
Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages.
Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051 - DOI: 10.1161/ATVBAHA.109.194043
Swirski FK, Weissleder R, Pittet MJ
Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - DOI: 10.1161/ATVBAHA.108.180521 - Cover
Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R
Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors.
Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086
Jaffer FA, Libby P, Weissleder R
Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228 - DOI: 10.1161/ATVBAHA.108.165530
Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L
A DNA-binding Gd chelate for the detection of cell death by MRI.
Chem Commun. 2009;(29):4444-6 - PMID: 19597620 - PMCID: PMC2754278 - DOI: 10.1039/b907375b
Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R
Upconverting luminescent nanomaterials: application to in vivo bioimaging.
Chem Commun. 2009;28:4188-90 - PMID: 19585016 - PMCID: PMC2748243 - DOI: 10.1039/b905927j
Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V
Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model.
Neuroimage. 2009;44(4):1304-11 - PMID: 19041402 - DOI: 10.1016/j.neuroimage.2008.10.038
McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Neuroimage. 2009;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022
Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O
Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology
Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357
Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819 - DOI: 10.1242/jcs.046813
Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A
Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure.
Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779
Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ
Multimodality Cardiovascular Molecular Imaging, Part II
Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054 - DOI: 10.1161/CIRCIMAGING.108.839092
Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ
Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium
Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045 - DOI: 10.1161/CIRCIMAGING.108.815050
Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L
Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia.
Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678
Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ
Diffusion MR tractography of the heart.
J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805 - DOI: 10.1186/1532-429X-11-47
Sosnovik DE, Caravan P
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents
J Cardiovasc Magn Reson. 2009;2:87-94
Im H, Lesuffleur A, Lindquist NC, Oh SH
Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing.
Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634 - DOI: 10.1021/ac802276x
Koh I, Hong R, Weissleder R, Josephson L
Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions.
Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647 - DOI: 10.1021/ac802717c
Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J
Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum.
J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731 - DOI: 10.1021/jm801654y
Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B
Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1.
Mol Cancer Ther. 2009;18(2):285-94 - PMID: 19844198 - PMCID: PMC2818668 - DOI: 10.1038/mt.2009.232
Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, Garcia-Anoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO
Mutant Sodium Channel for Tumor Therapy.
Mol Cancer Ther. 2009;17(5):810-9 - PMID: 19259066 - PMCID: PMC2751883 - DOI: 10.1038/mt.2009.33
Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L
The antiproliferative cytostatic effects of a self-activating viridin prodrug.
Mol Cancer Ther. 2009;8(6):1666-1675 - PMID: 19509266 - PMCID: PMC2740925 - DOI: 10.1158/1535-7163.MCT-08-1012
Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton A, Waterman P, Figueiredo JL, Kohler R, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ
Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle
Neoplasia. 2009;11(5):459-468 - PMID: 19412430 - PMCID: PMC2672160 - Cover
Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM
High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model.
ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v
Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ
Implantable diagnostic device for cancer monitoring.
Biosens Bioelectron. 2009;24(11):3252-7 - PMID: 19442510 - PMCID: PMC2738970 - DOI: 10.1016/j.bios.2009.04.010
Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L
Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation.
J Comb Chem. 2009;12(1):57-64 - PMID: 19928910 - PMCID: PMC2877490 - DOI: 10.1021/cc900141b
Higgins JM, Eddington DT, Bhatia SN, Mahadevan L
Statistical dynamics of flowing red blood cells by morphological image processing.
PLoS Comput Biol. 2009;5(2):e1000288 - PMID: 19214200 - PMCID: PMC2631282 - DOI: 10.1371/journal.pcbi.1000288
Piccirillo G M, Binda E, Fiocco R, Vescovi L, Shah K
Brain cancer stem cells.
J Mol Med. 2009;87(11):1087-95 - PMID: 19784875 - DOI: 10.1007/s00109-009-0535-3
Brown D, Breton S, Ausiello DA, Marshansky V
Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology.
Traffic. 2009;10(3):275-84 - PMID: 19170982 - PMCID: PMC2896909 - DOI: 10.1111/j.1600-0854.2008.00867.x
Kawada J, Zou P, Mazitschek R, Bradner JE, Cohen JI
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
J Biol Chem. 2009;284(25):17102-9 - PMID: 19386607 - PMCID: PMC2719348 - DOI: 10.1074/jbc.M809090200
Tharp A, Laha M, Panizzi P, Thompson M, Fuentes-Prior P, Bock P
Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and Kringle 5 of the substrate.
J Biol Chem. 2009;284(29):19511-21 - PMID: 19473980 - PMCID: PMC2740577 - DOI: 10.1074/jbc.M109.005512
Chen S, Reynolds F, Yu L, Weissleder R, Josephson L
A screening paradigm for the design of improved polymer-coated superparamagnetic iron oxide nanoparticles
J Mater Chem. 2009;19:6387-6392
McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA
Multimodal Nanoagents for the Detection of Intravascular Thrombi.
Bioconjug Chem. 2009;20(6):1251-5 - PMID: 19456115 - PMCID: PMC2733224 - DOI: 10.1021/bc9001163
Devaraj NK*, Keliher EJ*, Thurber GM, Nahrendorf M, Weissleder R
(18)F Labeled Nanoparticles for in Vivo PET-CT Imaging.
Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737 - DOI: 10.1021/bc8004649
Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L
A Wortmannin-Cetuximab as a Double Drug.
Bioconjug Chem. 2009;20 :2185-2189 - PMID: 19883074 - PMCID: PMC3386608 - DOI: 10.1021/bc900176a
Garanger E, Weissleder R, Josephson L
A Multifunctional Single-Attachment-Point Reagent for Controlled Protein Biotinylation.
Bioconjug Chem. 2009;20(1):170-173 - PMID: 19072220 - PMCID: PMC2692913 - DOI: 10.1021/bc800392t
Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF
A colorimetric high throughput screen for the detection of heme crystallization inhibitors.
Antimicrob Agents Chemother. 2009;53(6):2564-8 - PMID: 19307367 - PMCID: PMC2687197 - DOI: 10.1128/AAC.01466-08
Bhaumik J, Weissleder R, McCarthy JR
Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers.
J Org Chem. 2009;74(16):5894-901 - PMID: 19610602 - PMCID: PMC2888918 - DOI: 10.1021/jo900832y
Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG
Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer.
Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160 - DOI: 10.1016/j.ijrobp.2009.06.002
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG
Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223 - DOI: 10.1016/j.ijrobp.2009.02.052
Kelly K*, Shaw SY*, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R.
Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.
Integr Biol (Camb). 2009;1(4):311-317 - PMID: 20023731 - PMCID: PMC2748356 - DOI: 10.1039/b821775k - Cover
Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer J, Aikawa E
Intravital Molecular Imaging of Small-Diameter Tissue-Engineered Vascular Grafts: A Feasibility Study.
Tissue Eng. 2009;16(4):597-607 - PMID: 19751103 - DOI: 10.1089/ten.TEC.2009.0466
Sales VL, Mettler BA, Engelmayr GC, Aikawa E, Bischoff J, Martin DP, Exarhopoulos A, Moses M, Schoen FJ, Sacks M, Mayer J
Endothelial Progenitor Cells as a Sole Source for Ex vivo Seeding of Tissue-engineered Heart Valves.
Tissue Eng. 2009;16(1):257-67 - PMID: 19698056 - PMCID: PMC2811057 - DOI: 10.1089/ten.TEA.2009.0424
Pittet MJ
Behavior of immune players in the tumor microenvironment.
Curr Opin Oncol. 2009;21(1):53-9 - PMID: 19125019 - PMCID: PMC2901856 - DOI: 10.1097/CCO.0b013e32831bc38a
Belleannee C, Da Silva N, Shum WW, Marsolais M, Laprade R, Brown D, Breton S
Segmental Expression of the Bradykinin Type 2 Receptor in Rat Efferent Ducts and Epididymis and Its Role in the Regulation of Aquaporin 9.
Biol Reprod. 2009;80(1):134-43 - PMID: 18829705 - PMCID: PMC2804812 - DOI: 10.1095/biolreprod.108.070797 - Cover
Comper WD, Russo LM
The glomerular filter: an imperfect barrier is required for perfect renal function.
Curr Opin Nephrol Hy. 2009;18(4):336-42 - PMID: 19474730 - DOI: 10.1097/MNH.0b013e32832cb96a
Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, Aikawa M
Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II.
Lab Invest. 2009;89(3):315-26 - PMID: 19153555 - PMCID: PMC2932654 - DOI: 10.1038/labinvest.2008.167 - Cover
Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
Gynecol Oncol. 2009;112(3):616-22 - PMID: 19135233 - PMCID: PMC2664404 - DOI: 10.1016/j.ygyno.2008.11.018
Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U
Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.
Bone. 2009;44:190-198 - PMID: 19007918 - PMCID: PMC2656637 - DOI: 10.1016/j.bone.2008.10.036
Thurber GM, Figueiredo JL, Weissleder R
Multicolor Fluorescent Intravital Live Microscopy (FILM) for Surgical Tumor Resection in a Mouse Xenograft Model.
PLoS ONE. 2009;4(11):e8053 - PMID: 19956597 - PMCID: PMC2779447 - DOI: 10.1371/journal.pone.0008053
Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S
Systems-level modeling of cancer-fibroblast interaction.
PLoS ONE. 2009;4(9):e6888 - PMID: 19727395 - PMCID: PMC2731225 - DOI: 10.1371/journal.pone.0006888
Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S
The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis.
PLoS ONE. 2009;4(2):e4471 - PMID: 19214237 - PMCID: PMC2637605 - DOI: 10.1371/journal.pone.0004471
Wildgruber M, Lee H, Chudnovskiy A, Yoon T, Etzrodt M, Pittet M, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski F
Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.
PLoS ONE. 2009;4(5):e5663 - PMID: 19461894 - PMCID: PMC2680949 - DOI: 10.1371/journal.pone.0005663
Bian Y, Sun M, Silver M, Ho KK, Marchionni MA, Caggiano AO, Stone JR, Amende I, Hampton TG, Morgan JP, Yan X
Neuregulin-1 Attenuated Doxorubicin-Induced Decrease in Cardiac Troponins.
Am J Physiol-Heart C. 2009;297(6):H1974-83 - PMID: 19801490 - PMCID: PMC2793128 - DOI: 10.1152/ajpheart.01010.2008
Van Hoek AN, Bouley R, Lu YX, Silberstein CM, Brown D, Wax MB, Patil RV
Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.
Am J Physiol Renal Physiol. 2009;296(6):F1396-404 - PMID: 19297454 - PMCID: PMC2692439 - DOI: 10.1152/ajprenal.00018.2009
Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF
Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression.
Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332 - DOI: 10.1152/ajprenal.90762.2008
McCarthy JR, Bhaumik J, Merbouh N, Weissleder R
High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins.
Org Biomol Chem. 2009;7(17):3430-6 - PMID: 19675897 - PMCID: PMC2749955 - DOI: 10.1039/b908713c
Ueno T, Kaneko K, Katano H, Sato Y, Mazitschek R, Tanaka K, Hattori S, Irie S, Sata T, Ogawa-Goto K
Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER.
Exp Cell Res. 2009;316(3):329-40 - PMID: 19932094 - DOI: 10.1016/j.yexcr.2009.11.009
Pastor-Soler NM, Fisher JS, Sharpe R, Hill E, Van Hoek A, Brown D, Breton S
Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones.
Reproduction. 2009;139(3):613-21 - PMID: 19948840 - PMCID: PMC3773695 - DOI: 10.1530/REP-09-0284
Tsai CC, Vinegoni C, Weissleder R
Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide.
Opt Express. 2009;17(24):21723-31 - PMID: 19997414 - PMCID: PMC2805120
Mansuripur M, Zakharian AR, Lesuffleur A, Oh SH, Jones RJ, Lindquist NC, Im H, Kobyakov A, Moloney JV
Plasmonic nano-structures for optical data storage.
Opt Express. 2009;17(16):14001-14 - PMID: 19654809
Vinegoni C, Fexon L, Fumene Feruglio P, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R
High throughput transmission optical projection tomography using low cost graphics processing unit
Opt Express. 2009;17(25):22320-22332 - PMID: 20052155 - PMCID: PMC2805020 - Cover
Henry F, Cote D, Randolph M, Rust E, Redmond R, Kochevar I, Lin CP, Winograd J
Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy.
Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671 - DOI: 10.1097/PRS.0b013e318191c5b8
Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U
Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects.
Sens Actuat B-Chem. 2009;138(2):591-597 - PMID: 20161242 - PMCID: PMC2706141 - DOI: 10.1016/j.snb.2009.02.037
Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R
Normalized Born ratio for fluorescence optical projection tomography.
Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918
Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R
Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles
Opt Lett. 2009;34(17):2566-8 - PMID: 19724491 - PMCID: PMC2749971
Kumar A, Chung E, Raymond S, van de Water J, Shah K, Fukumura D, Jain R, Bacskai B, Boas D
Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast.
Opt Lett. 2009;34(13):2066-8 - PMID: 19572001 - PMCID: PMC2872111
Vonken EJ, Korosoglou G, Yu J, Schar M, Weissleder R, Stuber M
On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA).
Magn Reson Med. 2009;62(2):314-24 - PMID: 19526511 - PMCID: PMC2742771 - DOI: 10.1002/mrm.22027
Shum WW, Da Silva N, Brown D, Breton S
Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk.
J Exp Biol. 2009;212(Pt 11):1753-61 - PMID: 19448084 - PMCID: PMC2683015 - DOI: 10.1242/jeb.027284 - Cover
Brown D, Paunescu TG, Breton S, Marshansky V
Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking.
J Exp Biol. 2009;212(Pt 11):1762-72 - PMID: 19448085 - PMCID: PMC2683016 - DOI: 10.1242/jeb.028803 - Cover
Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS
Genetically engineered T cells to target EGFRvIII expressing glioblastoma.
J Neuro-Oncol. 2009;94(3):373-82 - PMID: 19387557 - PMCID: PMC2730985 - DOI: 10.1007/s11060-009-9889-1
Celso CL, Wu JW, Lin CP
In vivo imaging of hematopoietic stem cells and their microenvironment.
J Biophotonics. 2009;2(11):619-631 - PMID: 19847800 - DOI: 10.1002/jbio.200910072
Hilderbrand SA
Labels and probes for live cell imaging: overview and selection guide.
Methods Mol Biol. 2009;591:17-45 - PMID: 19957122 - DOI: 10.1007/978-1-60761-404-3_2
Sun N, Liu Y, Lee H, Weissleder R, Ham D
CMOS RF Biosensor Utilizing Nuclear Magnetic Resonance
IEEE J Solid-ST Circ. 2009;44:1629-1643
Baier ND, Hahn PF, Gervais DA, Samir A, Halpern EF, Mueller PR, Harisinghani MG
Fine-needle aspiration biopsy of thyroid nodules: experience in a cohort of 944 patients.
AJR Am J Roentgenol. 2009;193(4):1175-9 - PMID: 19770344 - DOI: 10.2214/AJR.08.1840
Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG
Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model.
AJR Am J Roentgenol. 2009;193(3):W230-7 - PMID: 19696264 - DOI: 10.2214/AJR.08.2175
Deliolanis N, Dunham J, Wurdinger T, Figueiredo J, Bakhos T, Ntziachristos V
In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography.
J Biomed Opt. 2009;14(3):030509 - PMID: 19566290 - PMCID: PMC2881930 - DOI: 10.1117/1.3149854
Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W
Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations.
Arch Pathol Lab Med. 2009;133(12):1949-53 - PMID: 19961250 - PMCID: PMC3694269 - DOI: 10.1043/1543-2165-133.12.1949
Razansky D, Vinegoni C, Ntziachristos V
Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography.
Phys Med Biol. 2009;54:2769-2777 - PMID: 19369709 - DOI: 10.1088/0031-9155/54/9/012
Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R
Enhancing navigation in biomedical databases by community voting and database-driven text classification.
BMC Bioinformatics. 2009;10(1):317 - PMID: 19799796 - PMCID: PMC2768718
Boland GW, Guimaraes AS, Mueller PR
The evolving radiology landscape: the importance of effective leadership.
Eur J Radiol. 2009;19(10):2321-5 - PMID: 19471944 - DOI: 10.1007/s00330-009-1427-1
Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F
Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections.
Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450 - DOI: 10.1017/S1431927609090813
Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J
Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.
Bioorg Med Chem Lett. 2009;20(1):228-31 - PMID: 19914064 - DOI: 10.1016/j.bmcl.2009.10.133
Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J
Antiplasmodial activity of piperazine sulfonamides.
Bioorg Med Chem Lett. 2009;20(1):218-21 - PMID: 19914069 - DOI: 10.1016/j.bmcl.2009.10.