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Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, Shin LM, Fayad ZA, Pitman RK
Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study.
Lancet. 2017;389(10071):834-845 - PMID: 28088338
Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Nature. 2017;547(7663):355-359 - PMID: 28678782
Miller MA, Weissleder R
Imaging of anticancer drug action in single cells
Nat Rev Cancer. 2017;17(7):399–414 - PMID: 28642603
Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M
Cellular uptake of nanoparticles: journey inside the cell.
Chem Soc Rev. 2017;46(14):4218-4244 - PMID: 28585944 - PMCID: PMC5593313
Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL
Cohesin Loss Eliminates All Loop Domains.
Cell. 2017;171(2):305-320.e24 - PMID: 28985562
Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M
Macrophages Facilitate Electrical Conduction in the Heart
Cell. 2017;169:510-522 - PMID: 28431249 - PMCID: PMC5474950
Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK
Origins of lymphatic and distant metastases in human colorectal cancer.
Science. 2017;357(6346):55-60 - PMID: 28684519 - PMCID: PMC5536201
Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, Mount C, Onozato ML, Nahed BV, Wakimoto H, Curry WT, Iafrate AJ, Rivera MN, Frosch MP, Golub TR, Brastianos PK, Getz G, Patel AP, Monje M, Cahill DP, Rozenblatt-Rosen O, Louis DN, Bernstein BE, Regev A, Suvà ML
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.
Science. 2017;355(6332):ePub - PMID: 28360267 - PMCID: PMC5519096
Flavahan WA, Gaskell E, Bernstein BE
Epigenetic plasticity and the hallmarks of cancer.
Science. 2017;357(6348):ePub - PMID: 28729483
King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng Jr RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R
IRF3 and type I interferons fuel a fatal response to myocardial infarction
Nature Med. 2017;:ePub - PMID: 29106401
Pfirschke C, Siwicki M, Liao HW, Pittet MJ
Tumor Microenvironment: No Effector T Cells without Dendritic Cells.
Cancer Cell. 2017;31(5):614-615 - PMID: 28486102
Frenk NE, Spring L, Muzikansky A, Vadvala HV Gurski JM Jr, Henderson LE, Mino-Kenudson M, Ly A, Bardia A, Finkelstein D, Engelman J, Mueller PR, Juric D, Weissleder R
High-Content Biopsies Facilitate Molecular Analyses and Do Not Increase Complication Rates in Patients With Advanced Solid Tumors
JCO Precis Oncol. 2017;1:1-9
Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R
Evolution of macromolecular complexity in drug delivery systems
Nat Rev Chem. 2017;1:0063
Miller MA
Nanoparticles improve economic mileage for CARs.
Sci Transl Med. 2017;9(387):ePub - PMID: 28446684
Yang KS*, Im H*, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R
Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy
Sci Transl Med. 2017;9(391):eaal3226 - PMID: 28539469
Miller MA
Counting on carbon quantum dots to clear infection
Sci Transl Med. 2017;9(399):eaao0969
Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts
Sci Transl Med. 2017;9(392):eaal0225 - PMID: 28566423
Arlauckas SP*, Garris CS*, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ
In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy
Sci Transl Med. 2017;9(389):eaal3604 - PMID: 28490665 - Cover
Miller MA
Driver mutations take the wheel in invasive yet nonmalignant disease.
Sci Transl Med. 2017;9(393):ePub - PMID: 28592567
Miller MA
Nanotransfection brings progress that’s more than skin-deep
Sci Transl Med. 2017;9(405):eaao4216
Castro CM
Good to the last "emulsified" drop.
Sci Transl Med. 2017;9(373):ePub - PMID: 28100835
King KR
Stunning neutrophils changes the forecast: No more showers.
Sci Transl Med. 2017;9(388):ePub - PMID: 28469035
Miller MA
Richer data with personalized GEMs.
Sci Transl Med. 2017;9(381):ePub - PMID: 28298424
King KR
Squeeze-E squeeze-E.
Sci Transl Med. 2017;9(382):ePub - PMID: 28330860
Frodermann V, Nahrendorf M
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2017;38(3):198-200 - PMID: 28158564
Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard B, Neidhart M, Stroes ESG, Catapano AL, Bekkering S
Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.
Eur Heart J. 2017;:ePub - PMID: 29069365
Nahrendorf M, Swirski FK
Cholesterol, CCR2, and monocyte phenotypes in atherosclerosis.
Eur Heart J. 2017;38(20):1594-1596 - PMID: 28329093
Hoyer FF, Nahrendorf M
Neutrophil contributions to ischaemic heart disease.
Eur Heart J. 2017;38(7):465-472 - PMID: 28363210
Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.
J Exp Med. 2017;214(11):3293-3310 - PMID: 28978634 - PMCID: PMC5679174
Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK
Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study.
J Am Coll Cardiol. 2017;69(20):2502-2513 - PMID: 28521888
Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN
Unraveling Vascular Inflammation: From Immunology to Imaging.
J Am Coll Cardiol. 2017;70(11):1403-1412 - PMID: 28882238 - PMCID: PMC5658004
Alaarg A, Pérez-Medina C, Metselaar JM, Nahrendorf M, Fayad ZA, Storm G, Mulder WJM
Applying nanomedicine in maladaptive inflammation and angiogenesis.
Adv Drug Deliv Rev. 2017;119:143-158 - PMID: 28506745 - PMCID: PMC5682240
Miller MA, Weissleder R
Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior
Adv Drug Deliv Rev. 2017;113:61-86 - PMID: 27266447 - PMCID: PMC5136524
Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ
mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.
J Clin Invest. 2017;127(6):2433-2437 - PMID: 28481220 - PMCID: PMC5451245
Seo KJ, Qiang Y, Bilgin I, Kar S, Vinegoni C, Weissleder R, Fang H
Transparent Electrophysiology Microelectrodes and Interconnects from Metal Nanomesh.
ACS Nano. 2017;11(4):4365-4372 - PMID: 28391679
Park J, Lin HY, Assaker JP, Jeong S, Huang CH, Kurdi A, Lee K, Fraser K, Min C, Eskandari S, Routray S, Tannous BA, Abdi R, Riella L, Chandraker A, Castro CM, Weissleder R, Lee H, Azzi JR
Integrated Kidney Exosome Analysis (iKEA) For The Detection Of Kidney Transplant Rejection.
ACS Nano. 2017;:ePub - PMID: 29053921
Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H
Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection.
ACS Nano. 2017;11(10):10062-10069 - PMID: 28792732
Park K, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H
Nano-Magnetic System For Rapid Diagnosis Of Acute Infection.
ACS Nano. 2017;:ePub - PMID: 29121461
Park CO, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JH, Jung Y, Watanabe R, Fuhlbrigge RC, Carbone FR, Gebhardt T, Clark RA, Lin CP, Kupper TS
Staged development of long lived TCRαβ Th17 resident memory T cell population to Candida albicans after skin infection.
J Allergy Clin Immunol. 2017;:ePub - PMID: 29128674
Swirski FK, Nahrendorf M
Inflammation: Old, caffeinated, and healthy.
Nat Rev Cardiol. 2017;14(4):194-196 - PMID: 28250451
Harada T, Ohguchi H, Grondin Y, Kikuchi S, Sagawa M, Tai YT, Mazitschek R, Hideshima T, Anderson KC
HDAC3 regulates DNMT1 expression in multiple myeloma: Therapeutic implications.
Leukemia. 2017;:ePub - PMID: 28490812 - PMCID: PMC5681897
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL
PD-L1 is an activation-independent marker of brown adipocytes.
Nat Commun. 2017;8(1):647 - PMID: 28935898 - PMCID: PMC5608754
Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M
Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease.
Nat Commun. 2017;8:14064 - PMID: 28091604 - PMCID: PMC5241815
Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.
Nat Commun. 2017;8:15142 - PMID: 28485378 - PMCID: PMC5436068
Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R
Nano-palladium is a cellular catalyst for in vivo chemistry
Nat Commun. 2017;8:15906 - PMID: 28699627 - PMCID: PMC5510178
Kitano K, Schwartz DM, Zhou H, Gilpin SE, Wojtkiewicz GR, Ren X, Sommer CA, Capilla AV, Mathisen DJ, Goldstein AM, Mostoslavsky G, Ott HC
Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts.
Nat Commun. 2017;8(1):765 - PMID: 29018244 - PMCID: PMC5635127
Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.
Nat Commun. 2017;8:14293 - PMID: 28176769 - PMCID: PMC5309815
Grossman SR, Zhang X, Wang L, Engreitz J, Melnikov A, Rogov P, Tewhey R, Isakova A, Deplancke B, Bernstein BE, Mikkelsen TS, Lander ES
Systematic dissection of genomic features determining transcription factor binding and enhancer function.
Proc Natl Acad Sci U S A. 2017;114(7):E1291-E1300 - PMID: 28137873 - PMCID: PMC5321001
Chen L, Lee JW, Chou CL, Nair AV, Battistone MA, Păunescu TG, Merkulova M, Breton S, Verlander JW, Wall SM, Brown D, Burg MB, Knepper MA
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq.
Proc Natl Acad Sci U S A. 2017;114(46):E9989-E9998 - PMID: 29089413
Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C
Imaging the emergence and natural progression of spontaneous autoimmune diabetes.
Proc Natl Acad Sci U S A. 2017;114(37):E7776-E7785 - PMID: 28839093 - PMCID: PMC5604023
He Q, Bouley R, Liu Z, Wein MN, Zhu Y, Spatz JM, Wang CY, Divieti Pajevic P, Plagge A, Babitt JL, Bastepe M
Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo.
Proc Natl Acad Sci U S A. 2017;114(45):E9559-E9568 - PMID: 29078380 - PMCID: PMC5692581
Chaudhury A, Noiret L, Higgins JM
White blood cell population dynamics for risk stratification of acute coronary syndrome.
Proc Natl Acad Sci U S A. 2017;114(46):12344-12349 - PMID: 29087321
Shah N, Wang P, Wongvipat J, Karthaus WR, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein BE, Long HW, Freedman ML, Arora VK, Zheng D, Sawyers CL
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer.
eLife. 2017;6:ePub - PMID: 28891793 - PMCID: PMC5593504
Wang CY, Core AB, Canali S, Zumbrennen-Bullough KB, Ozer S, Umans L, Zwijsen A, Babitt JL
Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice.
Blood. 2017;130(1):73-83 - PMID: 28438754 - PMCID: PMC5501149
Nigwekar SU, Weiser JM, Kalim S, Xu D, Wibecan JL, Dougherty SM, Mercier-Lafond L, Corapi KM, Eneanya ND, Holbrook EH, Brown D, Thadhani RI, Păunescu TG
Characterization and Correction of Olfactory Deficits in Kidney Disease.
J Am Soc Nephrol. 2017;28(11):3395-3403 - PMID: 28775001 - PMCID: PMC5661283
Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R
Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging.
Theranostics. 2017;7(5):1257-1265 - PMID: 28435463 - PMCID: PMC5399591
Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R
Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.
Nat Protoc. 2017;12(7):1472-1497 - PMID: 28686582
Bourgeois S, Bounoure L, Mouro-Chanteloup I, Colin Y, Brown D, Wagner CA
The ammonia transporter RhCG modulates urinary acidification by interacting with the vacuolar proton-ATPases in renal intercalated cells.
Kidney Int. 2017;:ePub - PMID: 29054531
Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman E, Garcia AR, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle B, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov MG, Sequist LV, Bernstein BE, Ebi H, Engelman JA, Faber AC
Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM.
Clin Cancer Res. 2017;:ePub - PMID: 29051323
Meyer IS, Jungmann A, Dieterich C, Zhang M, Lasitschka F, Werkmeister S, Haas J, Müller OJ, Boutros M, Nahrendorf M, Katus HA, Hardt SE, Leuschner F
The cardiac microenvironment uses non-canonical WNT signaling to activate monocytes after myocardial infarction.
EMBO Mol Med. 2017;9(9):1279-1293 - PMID: 28774883 - PMCID: PMC5582413
Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE
Preclinical investigation of gene-mediated cytotoxic immunotherapy and checkpoint blockade in glioblastoma.
Neuro Oncol. 2017;:ePub - PMID: 29016938
Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS
A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.
Cell Rep. 2017;21(3):784-797 - PMID: 29045844 - PMCID: PMC5687286
Godlewski J, Ferrer-Luna R, Rooj AK, Mineo M, Ricklefs F, Takeda YS, Nowicki MO, Salińska E, Nakano I, Lee H, Weissleder R, Beroukhim R, Chiocca EA, Bronisz A
MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer.
Stem Cell Reports. 2017;8(6):1497-1505 - PMID: 28528698 - PMCID: PMC5470095
Wilk K, Yeh SA, Mortensen LJ, Ghaffarigarakani S, Lombardo CM, Bassir SH, Aldawood ZA, Lin CP, Intini G
Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration.
Stem Cell Reports. 2017;8(4):933-946 - PMID: 28366454 - PMCID: PMC5390237
Brown D, Sands JM, Reckelhoff JF
APS: The Times They Are A-Changin'.
Physiology (Bethesda). 2017;32(6):400-401 - PMID: 28978629
She A, Kurtser I, Reis SA, Hennig K, Lai J, Lang A, Zhao WN, Mazitschek R, Dickerson BC, Herz J, Haggarty SJ
Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.
Cell Chem Biol. 2017;24(7):892-906.e5 - PMID: 28712747 - PMCID: PMC5695697
Hong S, Park KS, Weissleder R, Castro CM, Lee H
Facile silicification of plastic surface for bioassays.
Chem Commun. 2017;53(13):2134-2137 - PMID: 28134385 - PMCID: PMC5327824
Hideshima T, Mazitschek R, Qi J, Mimura N, Tseng JC, Kung AL, Bradner JE, Anderson KC
HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.
Oncotarget. 2017;8(46):80109-80123 - PMID: 29113288 - PMCID: PMC5655183
Hideshima T, Mazitschek R, Qi J, Mimura N, Tseng JC, Kung AL, Bradner JE, Anderson KC
HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer.
Oncotarget. 2017;:ePub - PMID: 28708596
Pulli B, Wojtkiewicz G, Iwamoto Y, Ali M, Zeller MW, Bure L, Wang C, Choi Y, Masia R, Guimaraes AR, Corey KE, Chen JW
Molecular MR Imaging of Myeloperoxidase Distinguishes Steatosis from Steatohepatitis in Nonalcoholic Fatty Liver Disease.
Radiology. 2017;:160588 - PMID: 28358240 - PMCID: PMC5548451
Fenn AM, Swirski FK
Monocytosis, Hypercholesterolemia, and the Kinase That Binds Them.
Arterioscler Thromb Vasc Biol. 2017;37(2):173-175 - PMID: 28122772
Kim DE, Kim JY, Schellingerhout D, Ryu JH, Lee SK, Jeon S, Lee JS, Kim J, Jang HJ, Park JE, Kim EJ, Kwon IC, Ahn CH, Nahrendorf M, Kim K
Quantitative Imaging of Cerebral Thromboemboli In Vivo: The Effects of Tissue-Type Plasminogen Activator.
Stroke. 2017;48(5):1376-1385 - PMID: 28432262
Tokarz D, Martins JS, Petit ET, Lin CP, Demay MB, Liu ES
Hormonal regulation of osteocyte perilacunar and canalicular remodeling in the Hyp mouse model of XLH.
J Bone Miner Res. 2017;:ePub - PMID: 29083055
Im H, Lee K, Weissleder R, Lee H, Castro CM
Novel nanosensing technologies for exosome detection and profiling.
Lab Chip. 2017;17(17):2892-2898 - PMID: 28745363 - PMCID: PMC5572557
Min C, Park J, Mun JK, Lim Y, Min J, Lim JW, Kang DM, Ahn HK, Shin TH, Cheon J, Lee HS, Weissleder R, Castro CM, Lee H
Integrated microHall magnetometer to measure the magnetic properties of nanoparticles.
Lab Chip. 2017;17(23):4000-4007 - PMID: 29067383 - PMCID: PMC5698130
Li W, Jin WW, Tsuji K, Chen Y, Nomura N, Su L, Yui N, Arthur J, Cotecchia S, Păunescu TG, Brown D, Lu HAJ
Direct interaction of ezrin and AQP2 and its role in AQP2 trafficking.
J Cell Sci. 2017;130(17):2914-2925 - PMID: 28754689
Vandoorne K, Nahrendorf M
Multiparametric Imaging of Organ System Interfaces.
Circ Cardiovasc Imaging. 2017;10(4):ePub - PMID: 28360260 - PMCID: PMC5419074
Stein-Merlob AF, Hara T, McCarthy JR, Mauskapf A, Hamilton JA, Ntziachristos V, Libby P, Jaffer FA
Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging.
Circ Cardiovasc Imaging. 2017;10(5):ePub - PMID: 28487316 - PMCID: PMC5509162
Vunnam S, Mazitschek R, Kariem NM, Reddy A, Rabeh W, Li L, O'Connor MJ, Al-Tel TH
Modular Bi-Directional One-Pot Strategies for the Diastereoselective Synthesis of Structurally Diverse Collections of Constrained β-Carboline-Benzoxazepines.
Chemistry. 2017;23(57):14182-14192 - PMID: 28770556
Global Cardiovascular Magnetic Resonance Registry (GCMR) Investigators, Kwong RY, Petersen SE, Schulz-Menger J, Arai AE, Bingham SE, Chen Y, Choi YL, Cury RC, Ferreira VM, Flamm SD, Steel K, Bandettini WP, Martin ET, Nallamshetty L, Neubauer S, Raman SV, Schelbert EB, Valeti US, Cao JJ, Reichek N, Young AA, Fexon L, Pivovarov M, Ferrari VA, Simonetti OP
The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments.
J Cardiovasc Magn Reson. 2017;19(1):23 - PMID: 28187739 - PMCID: PMC5303267
Turcotte R, Alt C, Runnels JM, Ito K, Wu JW, Zaher W, Mortensen LJ, Silberstein L, Côté DC, Kung AL, Ito K, Lin CP
Image-guided transplantation of single cells in the bone marrow of live animals.
Sci Rep. 2017;7(1):3875 - PMID: 28634334 - PMCID: PMC5478633
Nairz M, Haschka D, Dichtl S, Sonnweber T, Schroll A, Aßhoff M, Mindur JE, Moser PL, Wolf D, Swirski FK, Theurl I, Cerami A, Brines M, Weiss G
Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis.
Sci Rep. 2017;7(1):13012 - PMID: 29026145 - PMCID: PMC5638901
Beam AL, Kartoun U, Pai JK, Chatterjee AK, Fitzgerald TP, Shaw SY, Kohane IS
Predictive Modeling of Physician-Patient Dynamics That Influence Sleep Medication Prescriptions and Clinical Decision-Making.
Sci Rep. 2017;7:42282 - PMID: 28181568 - PMCID: PMC5299453
Iaconelli J, Lalonde J, Watmuff B, Liu B, Mazitschek R, Haggarty SJ, Karmacharya R
Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells.
ACS Chem Biol. 2017;12(8):2139-2148 - PMID: 28628306
Chousterman BG, Swirski FK, Weber GF
Cytokine storm and sepsis disease pathogenesis.
Semin Immunopathol. 2017;39(5):517-528 - PMID: 28555385
Conrad C, Dorzweiler K, Miller MA, Lauffenburger DA, Strik H, Bartsch JW
Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.
Fluids Barriers CNS. 2017;14(1):22 - PMID: 28806983 - PMCID: PMC5556623
Krukowski K, Ma J, Golonzhka O, Laumet GO, Gutti T, van Duzer JH, Mazitschek R, Jarpe MB, Heijnen CJ, Kavelaars A
HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy.
Pain. 2017;158(6):1126-1137 - PMID: 28267067 - PMCID: PMC5435512
Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK
Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study.
J Am Heart Assoc. 2017;6(11):e006241 - PMID: 29092845
Park YI, Kim E, Huang CH, Park KS, Castro CM, Lee H, Weissleder R
Facile Coating Strategy to Functionalize Inorganic Nanoparticles for Biosensing
Bioconjug Chem. 2017;28(1):33-37 - PMID: 27792877 - PMCID: PMC5474933
Nairz M, Theurl I, Swirski FK, Weiss G
"Pumping iron" - how macrophages handle iron at the systemic, microenvironmental, and cellular levels.
Pflugers Arch. 2017;469(3-4):397-418 - PMID: 28251312 - PMCID: PMC5362662
Stiekema LCA, Schnitzler JG, Nahrendorf M, Stroes ESG
The maturation of a 'neural-hematopoietic' inflammatory axis in cardiovascular disease.
Curr Opin Lipidol. 2017;28(6):507-512 - PMID: 28877089
Park YJ, Battistone MA, Kim B, Breton S
Relative contribution of clear cells and principal cells to luminal pH in the mouse epididymis.
Biol Reprod. 2017;96(2):366-375 - PMID: 28203710
Canali S, Wang CY, Zumbrennen-Bullough KB, Bayer A, Babitt JL
Bmp2 controls iron homeostasis in mice independent of Bmp6.
Am J Hematol. 2017;92(11):1204-1213 - PMID: 28815688
Oza AM, Tinker AV, Oaknin A, Shapira-Frommer R, McNeish IA, Swisher EM, Ray-Coquard I, Bell-McGuinn K, Coleman RL, O'Malley DM, Leary A, Chen LM, Provencher D, Ma L, Brenton JD, Konecny GE, Castro CM, Giordano H, Maloney L, Goble S, Lin KK, Sun J, Raponi M, Rolfe L, Kristeleit RS
Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2.
Gynecol Oncol. 2017;147(2):267-275 - PMID: 28882436
Tokarz D, Cisek R, Wein MN, Turcotte R, Haase C, Yeh SA, Bharadwaj S, Raphael AP, Paudel H, Alt C, Liu TM, Kronenberg HM, Lin CP
Intravital imaging of osteocytes in mouse calvaria using third harmonic generation microscopy.
PLoS ONE. 2017;12(10):e0186846 - PMID: 29065178 - PMCID: PMC5655444
Menezes TP, Hill E, de Alencar Moura A, Lobo MDP, Monteiro-Moreira ACO, Breton S, Machado-Neves M
Pattern of protein expression in the epididymis of Oligoryzomys nigripes (Cricetidae, Sigmodontinae).
Cell Tissue Res. 2017;:ePub - PMID: 29119327
Cheung PW, Ueberdiek L, Day J, Bouley R, Brown D
Protein phosphatase 2C (PP2C) is responsible for VP-induced dephosphorylation of AQP2 serine 261.
Am J Physiol Renal Physiol. 2017;:ajprenal.00004.2017 - PMID: 28381458 - PMCID: PMC5582913
Mamuya FA, Xie D, Lei L, Huang M, Tsuji K, Capen DE, Yang B, Weissleder R, Păunescu TG, Lu HJ
Deletion of β-1 integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis.
Am J Physiol Renal Physiol. 2017;:ajprenal.00038.2017 - PMID: 28701310 - PMCID: PMC5668581
Noiret L, Slater A, Higgins JM
Determinants of red blood cell alloantibody detection duration: analysis of multiply alloimmunized patients supports peritransfusion factors.
Transfusion. 2017;57(8):1930-1937 - PMID: 28639314
Li YX, Gautam V, Brüstle A, Cockburn IA, Daria VR, Gillespie C, Gaus K, Alt C, Lee WM
Flexible polygon-mirror based laser scanning microscope platform for multiphoton in-vivo imaging.
J Biophotonics. 2017;10(11):1526-1537 - PMID: 28164461
Conrad C, Miller MA, Bartsch JW, Schlomann U, Lauffenburger DA
Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.
Methods Mol Biol. 2017;1574:243-253 - PMID: 28315256
Im H, Yang K, Lee H, Castro CM
Characterization of Extracellular Vesicles by Surface Plasmon Resonance.
Methods Mol Biol. 2017;1660:133-141 - PMID: 28828653
Pérez-Medina C, Hak S, Reiner T, Fayad ZA, Nahrendorf M, Mulder WJM
Integrating nanomedicine and imaging.
Philos Trans A Math Phys Eng Sci. 2017;375(2107):ePub - PMID: 29038380 - PMCID: PMC5647268
Randino R, Gazzerro P, Mazitschek R, Rodriquez M
Synthesis and biological evaluation of Santacruzamate-A based analogues.
Bioorg Med Chem. 2017;:ePub - PMID: 29100734
Pera V, Tan X, Runnels J, Sardesai N, Lin CP, Niedre M
Diffuse fluorescence fiber probe for in vivo detection of circulating cells.
J Biomed Opt. 2017;22(3):37004 - PMID: 28290598 - PMCID: PMC5348644
Lee S, Courties G, Nahrendorf M, Weissleder R, Vinegoni C
Motion characterization scheme to minimize motion artifacts in intravital microscopy.
J Biomed Opt. 2017;22(3):36005 - PMID: 28253383 - PMCID: PMC5333764
Hartmann C, Patil R, Lin CP, Niedre MJ
Fluorescence detection, enumeration and characterization of single circulating cells <i>in vivo</i> technology, applications and future prospects.
Phys Med Biol. 2017;:ePub - PMID: 29115281
Brown D
The Discovery of Water Channels (Aquaporins).
Ann Nutr Metab. 2017;70 Suppl 1:37-42 - PMID: 28614812
Lu X, Galarneau MM, Higgins JM, Wood DK
A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow.
Microcirculation. 2017;:ePub - PMID: 28129479 - PMCID: PMC5505799
Je KH, Ryu WS, Lee SK, Kim EJ, Kim JY, Jang HJ, Park JE, Nahrendorf M, Schellingerhout D, Kim DE
Green-channel autofluorescence imaging: A novel and sensitive technique to delineate infarcts.
J Neurosci Methods. 2017;279:22-32 - PMID: 28104485
Soeken TA, Zhu H, DeMartelaere S, Davies BW, Kim M, Wang HC, Aden J, Grimm R, Alt C, Kochevar IE, Johnson AJ
Sealing of Corneal Lacerations Using Photoactivated Rose Bengal Dye and Amniotic Membrane.
Cornea. 2017;:ePub - PMID: 29140861
Vieson MD, Gojmerac AM, Khan D, Dai R, van Duzer JH, Mazitschek R, Caudell DL, Liao X, Luo XM, Reilly CM
Treatment with a selective histone deacetylase 6 inhibitor decreases lupus nephritis in NZB/W mice.
Histol Histopathol. 2017;:11885 - PMID: 28245046
Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK
Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography.
Coron Artery Dis. 2017;28(7):557-563 - PMID: 28704243
Dev S, Babitt JL
Overview of iron metabolism in health and disease.
Hemodial Int. 2017;21 Suppl 1:S6-S20 - PMID: 28296010
Shon SM, Jang HJ, Schellingerhout D, Kim JY, Ryu WS, Lee SK, Kim J, Park JY, Oh JH, Kang JW, Je KH, Park JE, Kim K, Kwon IC, Lee J, Nahrendorf M, Park JH, Kim DE
Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice.
Circ J. 2017;81(10):1528-1536 - PMID: 28883215
Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR
Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer.
Sci Adv. 2017;3(6):e1700341 - PMID: 28630930 - PMCID: PMC5473678
Miller MA, Arlauckas S, Weissleder R
Prediction of Anti-cancer Nanotherapy Efficacy by Imaging
Nanotheranostics. 2017;1(3):296-312 - PMID: 29071194 - PMCID: PMC5646731
Christensen HL, Păunescu TG, Matchkov V, Barbuskaite D, Brown D, Damkier HH, Praetorius J
The V-ATPase is expressed in the choroid plexus and mediates cAMP-induced intracellular pH alterations.
Physiol Rep. 2017;5(1):ePub - PMID: 28053225 - PMCID: PMC5256157
Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Golan K, Khatib E, Kumari A, Kollet O, Shakhar G, Butler JM, Rafii S, Adams RH, Scadden DT, Lin CP, Lapidot T
Distinct bone marrow blood vessels differentially regulate haematopoiesis.
Nature. 2016;532(7599):323-328 - PMID: 27074509
Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, Francis JM, Patel AA, Onozato ML, Riggi N, Livak KJ, Gennert D, Satija R, Nahed BV, Curry WT, Martuza RL, Mylvaganam R, Iafrate AJ, Frosch MP, Golub TR, Rivera MN, Getz G, Rozenblatt-Rosen O, Cahill DP, Monje M, Bernstein BE, Louis DN, Regev A, Suvà ML
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.
Nature. 2016;539(7628):309-313 - PMID: 27806376 - PMCID: PMC5465819
Drier Y, Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L, Qi J, Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster JC, Knoechel B, Bernstein BE
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.
Nat Genet. 2016;48(3):265-72 - PMID: 26829750 - PMCID: PMC4767593
Wang X, Lee RS, Alver BH, Haswell JR, Wang S, Mieczkowski J, Drier Y, Gillespie SM, Archer TC, Wu JN, Tzvetkov EP, Troisi EC, Pomeroy SL, Biegel JA, Tolstorukov MY, Bernstein BE, Park PJ, Roberts CW
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation.
Nat Genet. 2016;49(2):289-295 - PMID: 27941797 - PMCID: PMC5285474
Engblom C, Pfirschke C, Pittet MJ
The role of myeloid cells in cancer therapies.
Nat Rev Cancer. 2016;16(7):447-62 - PMID: 27339708
Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Cell. 2016;167(5):1310-1322.e17 - PMID: 27863245
Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, Pittet MJ
SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions
Science. 2016;352(6282):242-246 - PMID: 26989197 - PMCID: PMC4960636
Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, Suda T, Lin CP, Frenette PS, Ito K
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.
Science. 2016;354(6316):1156-1160 - PMID: 27738012 - PMCID: PMC5164878
Shema E, Jones D, Shoresh N, Donohue L, Ram O, Bernstein BE
Single-molecule decoding of combinatorially modified nucleosomes.
Science. 2016;352(6286):717-21 - PMID: 27151869 - PMCID: PMC4904710
Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
Nature Med. 2016;22(8):945-951 - PMID: 27428900 - PMCID: PMC4957133
Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Cell Stem Cell. 2016;20(2):233-246.e7 - PMID: 27989769 - PMCID: PMC5291795
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.
Cell Stem Cell. 2016;19(4):530-543 - PMID: 27524439 - PMCID: PMC5402355
Pfirschke C, Engblom C, Rickelt S, Cortez-Retamozo V, Garris C, Pucci F, Yamasaki T, Poirier-Colame V, Newton A, Redouane Y, Lin YJ, Wojtkiewicz G, Iwamoto Y, Mino-Kenudson M, Huynh TG, Hynes RO, Freeman GJ Kroemer G, Zitvogel L, Weissleder R, Pittet MJ
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
Immunity. 2016;44:1-12 - PMID: 26872698 - PMCID: PMC4758865
Siwicki M, Engblom C, Pittet MJ
Gal3 Links Inflammation and Insulin Resistance.
Cell Metab. 2016;24(5):655-656 - PMID: 27829136
Castro CM
Taking cancer drug screening very personally.
Sci Transl Med. 2016;8(367):367ec190 - PMID: 27903858
Weissleder R, Schwaiger MC, Gambhir SS, Hricak H
Imaging approaches to optimize molecular therapies
Sci Transl Med. 2016;8(355):355ps16 - PMID: 27605550
Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction
Sci Transl Med. 2016;8:342 - PMID: 27280687 - Cover
Malka R, Nathan DM, Higgins JM
Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring
Sci Transl Med. 2016;8:359ra130 - PMID: 27708063
van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.
Mol Cell. 2016;61(1):170-80 - PMID: 26687680 - PMCID: PMC4707994
van der Valk FM, Kuijk C, Verweij SL, Stiekema LC, Kaiser Y, Zeerleder S, Nahrendorf M, Voermans C, Stroes ES
Increased haematopoietic activity in patients with atherosclerosis.
Eur Heart J. 2016;38(6):425-432 - PMID: 27357356
Frodermann V, Nahrendorf M
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2016;:ePub - PMID: 26984866
Hong S, Pirovich D, Kilcoyne A, Huang CH, Lee H, Weissleder R
Supramolecular Metallo-Bioadhesive for Minimally Invasive Use
Adv Mater. 2016;28(39):8675-8680 - PMID: 27515068 - PMCID: PMC5144581
Libby P, Nahrendorf M, Swirski FK
Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum"
J Am Coll Cardiol. 2016;67(9):1091-103 - PMID: 26940931 - PMCID: PMC4779182
Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R
Quantitating drug-target engagement in single cells in vitro and in vivo.
Nat Chem Biol. 2016;13(2):168-173 - PMID: 27918558 - PMCID: PMC5630128
Reis SA, Ghosh B, Hendricks JA, Szantai-Kis DM, Törk L, Ross KN, Lamb J, Read-Button W, Zheng B, Wang H, Salthouse C, Haggarty SJ, Mazitschek R
Light-controlled modulation of gene expression by chemical optoepigenetic probes.
Nat Chem Biol. 2016;12(5):317-323 - PMID: 26974814 - PMCID: PMC4836974
Miller MA, Weissleder R
Imaging the pharmacology of nanomaterials by intravital microscopy: Towards understanding their biological behavior.
Adv Drug Deliv Rev. 2016;113:61-86 - PMID: 27266447 - PMCID: PMC5136524
Xie Q, Wu Q, Kim L, Miller TE, Liau BB, Mack SC, Yang K, Factor DC, Fang X, Huang Z, Zhou W, Alazem K, Wang X, Bernstein BE, Bao S, Rich JN
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.
J Clin Invest. 2016;126(7):2757-72 - PMID: 27322055 - PMCID: PMC4922685
Jeong S, Park J, Pathania D, Castro CM, Weissleder R, Lee H
Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
ACS Nano. 2016;10(2):1802-1809 - PMID: 26808216 - PMCID: PMC4802494
Mattoo H, Mahajan VS, Maehara T, Deshpande V, Della-Torre E, Wallace ZS, Kulikova M, Drijvers JM, Daccache J, Carruthers MN, Castellino F, Stone JR, Stone JH, Pillai S
Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
J Allergy Clin Immunol. 2016;138(3):825-38 - PMID: 26971690 - PMCID: PMC5014627
Sager HB, Hulsmans M, Lavine KJ, Beltrami Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M
Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.
Circ Res. 2016;119(7):853-64 - PMID: 27444755 - PMCID: PMC5378496
Nahrendorf M, Swirski FK
Abandoning M1/M2 for a Network Model of Macrophage Function.
Circ Res. 2016;119(3):414-7 - PMID: 27458196 - PMCID: PMC4965179
McAlpine CS, Swirski FK
Circadian Influence on Metabolism and Inflammation in Atherosclerosis.
Circ Res. 2016;119(1):131-41 - PMID: 27340272 - PMCID: PMC4922503
Swirski FK, Nahrendorf M
Bone Marrow Takes Center Stage in Cardiovascular Disease.
Circ Res. 2016;119(6):701-3 - PMID: 27587406 - PMCID: PMC5012290
Corey KE, Kartoun U, Zheng H, Chung RT, Shaw SY
Using an Electronic Medical Records Database to Identify Non-Traditional Cardiovascular Risk Factors in Nonalcoholic Fatty Liver Disease.
Am J Gastroenterol. 2016;111(5):671-6 - PMID: 26925881 - PMCID: PMC4864030
Chen YC, Backus KM, Merkulova M, Yang C, Brown D, Cravatt BF, Zhang C
Covalent Modulators of the Vacuolar ATPase.
J Am Chem Soc. 2016;139(2):639-642 - PMID: 28010062 - PMCID: PMC5274637
Goyal L, Saha SK, Liu LY, Siravegna G, Leshchiner I, Ahronian LG, Lennerz JK, Vu P, Deshpande V, Kambadakone A, Mussolin B, Reyes S, Henderson L, Sun JE, Van Seventer EE, Gurski JM, Baltschukat S, Schacher-Engstler B, Barys L, Stamm C, Furet P, Ryan DP, Stone JR, Iafrate AJ, Getz G, Graus Porta D, Tiedt R, Bardelli A, Juric D, Corcoran RB, Bardeesy N, Zhu AX
Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma.
Cancer Discov. 2016;7(3):252-263 - PMID: 28034880 - PMCID: PMC5433349
Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
Cancer Discov. 2016;6(4):382-99 - PMID: 26984351 - PMCID: PMC5087317 - Cover
Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, Raulet DH, Weinberg RA
Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells.
Cancer Discov. 2016;6(6):630-49 - PMID: 27072748 - PMCID: PMC4918202
Aryal B, Rotllan N, Araldi E, Ramírez CM, He S, Chousterman BG, Fenn AM, Wanschel A, Madrigal-Matute J, Warrier N, Martín-Ventura JL, Swirski FK, Suárez Y, Fernández-Hernando C
ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Nat Commun. 2016;7:12313 - PMID: 27460411 - PMCID: PMC4974469
Vinegoni C, Leon Swisher C, Fumene Feruglio P, Giedt RJ, Rousso DL, Stapleton S, Weissleder R
Real-time high dynamic range laser scanning microscopy.
Nat Commun. 2016;7:11077 - PMID: 27032979 - PMCID: PMC4821995
Roy J*, Kim B*, Hill E, Visconti P, Krapf D, Vinegoni C, Weissleder R, Brown D, Breton S
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging.
Nat Commun. 2016;7:10666 - PMID: 26868824 - PMCID: PMC4754344
Hosseini P, Abidi SZ, Du E, Papageorgiou DP, Choi Y, Park Y, Higgins JM, Kato GJ, Suresh S, Dao M, Yaqoob Z, So PT
Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease.
Proc Natl Acad Sci U S A. 2016;113(34):9527-32 - PMID: 27512047 - PMCID: PMC5003247
Hideshima T, Qi J, Paranal RM, Tang W, Greenberg E, West N, Colling ME, Estiu G, Mazitschek R, Perry JA, Ohguchi H, Cottini F, Mimura N, Görgün G, Tai YT, Richardson PG, Carrasco RD, Wiest O, Schreiber SL, Anderson KC, Bradner JE
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma.
Proc Natl Acad Sci U S A. 2016;113(46):13162-13167 - PMID: 27799547 - PMCID: PMC5135369
Kirschbaum K, Sonner JK, Zeller MW, Deumelandt K, Bode J, Sharma R, Krüwel T, Fischer M, Hoffmann A, Costa da Silva M, Muckenthaler MU, Wick W, Tews B, Chen JW, Heiland S, Bendszus M, Platten M, Breckwoldt MO
In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis.
Proc Natl Acad Sci U S A. 2016;113(46):13227-13232 - PMID: 27799546 - PMCID: PMC5135308
Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ
Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Proc Natl Acad Sci U S A. 2016;113(44):E6731-E6740 - PMID: 27791119 - PMCID: PMC5098679
Ramasamy S, Saez B, Mukhopadhyay S, Ding D, Ahmed AM, Chen X, Pucci F, Yamin R, Wang J, Pittet MJ, Kelleher CM, Scadden DT, Sweetser DA
Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway.
Proc Natl Acad Sci U S A. 2016;113(7):1871-6 - PMID: 26831087 - PMCID: PMC4763742
Swirski FK, Robbins CS, Nahrendorf M
Development and Function of Arterial and Cardiac Macrophages.
Trends Immunol. 2016;37(1):32-40 - PMID: 26748179 - PMCID: PMC4706986
Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D
Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
Blood. 2016;127(19):2327-36 - PMID: 26755707 - PMCID: PMC4865590
Canali S, Zumbrennen-Bullough KB, Core AB, Wang CY, Nairz M, Bouley R, Swirski FK, Babitt JL
Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Blood. 2016;129(4):405-414 - PMID: 27864295 - PMCID: PMC5270389
Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Jenny Lu HA, Brown D, Bouley R
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
J Am Soc Nephrol. 2016;:ePub - PMID: 26961350
Mumtaz R, Trepiccione F, Hennings JC, Huebner AK, Serbin B, Picard N, Ullah AK, Păunescu TG, Capen DE, Lashhab RM, Mouro-Chanteloup I, Alper SL, Wagner CA, Cordat E, Brown D, Eladari D, Hübner CA
Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an AE1 R607H Knockin Model.
J Am Soc Nephrol. 2016;28(5):1507-1520 - PMID: 27932475 - PMCID: PMC5407715
Trepiccione F, Gerber SD, Grahammer F, López-Cayuqueo KI, Baudrie V, Păunescu TG, Capen DE, Picard N, Alexander RT, Huber TB, Chambrey R, Brown D, Houillier P, Eladari D, Simons M
Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.
J Am Soc Nephrol. 2016;27(11):3320-3330 - PMID: 27044666 - PMCID: PMC5084887
Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Lu HA, Brown D, Bouley R
EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.
J Am Soc Nephrol. 2016;27(10):3105-3116 - PMID: 27694161 - PMCID: PMC5042667
Pathania D*, Im H*, Kilcoyne A, Sohani AR, Fexon L, Pivovarov M, Abramson JS, Randall TC, Chabner BA, Weissleder R, Lee H, Castro CM
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Theranostics. 2016;6(10):1603-10 - PMID: 27446494 - PMCID: PMC4955059
Ricklefs F, Mineo M, Rooj AK, Nakano I, Charest A, Weissleder R, Breakefield XO, Chiocca EA, Godlewski J, Bronisz A
Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity.
Cancer Res. 2016;76(10):2876-2881 - PMID: 27013191 - PMCID: PMC4873326
Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.
Kidney Int. 2016;1(3):135-143 - PMID: 27990496 - PMCID: PMC5155703
Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M
Glucagon-like peptide-1 receptor activation attenuates platelet aggregation and thrombosis.
Diabetes. 2016;65(6):1714-23 - PMID: 26936963
Gainor JF, Shaw AT, Sequist LV, Fu X, Azzoli CG, Piotrowska Z, Huynh TG, Zhao L, Fulton L, Schultz K, Howe E, Farago AF, Sullivan RJ, Stone JR, Digumarthy S, Moran T, Hata AN, Yagi Y, Yeap BY, Engelman JA, Mino-Kenudson M
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer (NSCLC): A Retrospective Analysis.
Clin Cancer Res. 2016;22(18):4585-93 - PMID: 27225694 - PMCID: PMC5026567
Miller MA, Sullivan RJ, Lauffenburger DA
Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.
Clin Cancer Res. 2016;23(3):623-629 - PMID: 27895032 - PMCID: PMC5290119
Dykstra B, Lee J, Mortensen LJ, Yu H, Wu ZL, Lin CP, Rossi DJ, Sackstein R
Glycoengineering of E-selectin ligands by intracellular versus extracellular fucosylation differentially affects osteotropism of human mesenchymal stem cells.
Stem Cells. 2016;34(10):2501-2511 - PMID: 27335219 - PMCID: PMC5064874
Gee MS, Ghazani AA, Haq R, Wargo JA, Sebas M, Sullivan RJ, Lee H, Weissleder R
Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood.
Nanomedicine. 2016;13(3):821-828 - PMID: 27993725 - PMCID: PMC5392428
Pucci F, Rickelt S, Newton AP, Garris C, Nunes E, Evavold C, Pfirschke C, Engblom C, Mino-Kenudson M, Hynes RO, Weissleder R, Pittet MJ
PF4 Promotes Platelet Production and Lung Cancer Growth.
Cell Rep. 2016;17(7):1764-1772 - PMID: 27829148 - PMCID: PMC5108525
Reckelhoff JF, Brown D, Molina PE
APS Takes a Look in the Mirror.
Physiology (Bethesda). 2016;31(6):384-385 - PMID: 27708041
Hall JL, Ryan JJ, Bray BE, Brown C, Lanfear D, Newby LK, Relling MV, Risch NJ, Roden DM, Shaw SY, Tcheng JE, Tenenbaum J, Wang TN, Weintraub WS
Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association.
Circ Cardiovasc Genet. 2016;9(2):193-202 - PMID: 26976545 - PMCID: PMC5646218
Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F
Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
Circ Heart Fail. 2016;9(1):e002724 - PMID: 26721917 - PMCID: PMC4698901
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I
Statin use is Associated With Reduced Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2016;14(7):973-9 - PMID: 26905907 - PMCID: PMC4912917
Meimetis LG, Giedt R, Mikyla H, Carlson J, Kohler R, Pirovich DB, Weissleder R
Fluorescent vinblastine probes for live cell imaging
Chem Commun. 2016;52(64):9953-6 - PMID: 27439765 - PMCID: PMC4970878
Huang P, Almeciga-Pinto I, Jarpe M, van Duzer JH, Mazitschek R, Yang M, Jones SS, Quayle SN
Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.
Oncotarget. 2016;8(2):2694-2707 - PMID: 27926524 - PMCID: PMC5356834
Cotter K, Liberman R, Sun-Wada G, Wada Y, Sgroi D, Naber S, Brown D, Breton S, Forgac M
The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.
Oncotarget. 2016;7(29):46142-46157 - PMID: 27323815 - PMCID: PMC5216787
Albadawi H, Chen JW, Oklu R, Wu Y, Wojtkiewicz G, Pulli B, Milner JD, Cambria RP, Watkins MT
Spinal Cord Inflammation: Molecular Imaging after Thoracic Aortic Ischemia Reperfusion Injury.
Radiology. 2016;:152222 - PMID: 27509542 - PMCID: PMC5207124
Babaev VR, Ding L, Zhang Y, May JM, Lin CP, Fazio S, Linton MF
Macrophage IκB Kinase α Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2016;36(4):598-607 - PMID: 26848161 - PMCID: PMC4808396
Dutta P, Hoyer FF, Sun Y, Iwamoto Y, Tricot B, Weissleder R, Magnani JL, Swirski FK, Nahrendorf M
E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial Infarction.
Arterioscler Thromb Vasc Biol. 2016;36(9):1802-8 - PMID: 27470513 - PMCID: PMC5001901
Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK
Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study.
Arterioscler Thromb Vasc Biol. 2016;36(11):2229-2238 - PMID: 27634834
Calcagno C, Mulder WJ, Nahrendorf M, Fayad ZA
Systems Biology and Noninvasive Imaging of Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2016;36(2):e1-8 - PMID: 26819466 - PMCID: PMC4861402
Im H, Park YI, Pathania D, Castro CM, Weissleder R, Lee H
Digital diffraction detection of protein markers for avian influenza.
Lab Chip. 2016;16(8):1340-5 - PMID: 26980325 - PMCID: PMC4829473
Lindau A, Härdtner C, Hergeth SP, Blanz KD, Dufner B, Hoppe N, Anto-Michel N, Kornemann J, Zou J, Gerhardt LM, Heidt T, Willecke F, Geis S, Stachon P, Wolf D, Libby P, Swirski FK, Robbins CS, McPheat W, Hawley S, Braddock M, Gilsbach R, Hein L, von Zur Mühlen C, Bode C, Zirlik A, Hilgendorf I
Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.
Basic Res Cardiol. 2016;111(2):20 - PMID: 26891724 - PMCID: PMC4759214
Rischpler C, Dirschinger RJ, Nekolla SG, Kossmann H, Nicolosi S, Hanus F, van Marwick S, Kunze KP, Meinicke A, Götze K, Kastrati A, Langwieser N, Ibrahim T, Nahrendorf M, Schwaiger M, Laufwitz KL
Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome
Circ Cardiovasc Imaging. 2016;9:e004316 - PMID: 27056601 - PMCID: PMC4826716
Kilcoyne A, Harisinghani MG, Mahmood U
Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles.
J Nucl Med. 2016;57(Suppl 3):105S-110S - PMID: 27694162
Vunnam S, Reddy A, Mazitschek R, Lukens AK, Wirth DF, Li L, Naumov P, O'Connor MJ, Al-Tel TH
Intramolecular Diaza-Diels-Alder Protocol: A Novel Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.
Chemistry. 2016;23(17):4137-4148 - PMID: 27997727
Oudin MJ, Barbier L, Schäfer C, Kosciuk T, Miller MA, Han S, Jonas O, Lauffenburger DA, Gertler FB
MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.
Mol Cancer Ther. 2016;16(1):143-155 - PMID: 27811011 - PMCID: PMC5359014
Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R
Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response
Sci Rep. 2016;6:32985 - PMID: 27609668 - PMCID: PMC5017129
Wu JW, Turcotte R, Alt C, Runnels JM, Tsao H, Lin CP
Defining Clonal Color in Fluorescent Multi-Clonal Tracking
Sci Rep. 2016;6:24303 - PMID: 27073117 - PMCID: PMC4829845
Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC
A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever.
Sci Rep. 2016;6:32878 - PMID: 27605393 - PMCID: PMC5015101
Song J, Leon Swisher C, Im H, Jeong S, Pathania D, Iwamoto Y, Pivovarov M, Weissleder R, Lee H
Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography.
Sci Rep. 2016;6:24681 - PMID: 27098438 - PMCID: PMC4838824
Yang Z, Concannon J, Ng KS, Seyb K, Mortensen LJ, Ranganath S, Gu F, Levy O, Tong Z, Martyn K, Zhao W, Lin CP, Glicksman MA, Karp JM
Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation.
Sci Rep. 2016;6:30263 - PMID: 27457881 - PMCID: PMC4960598
Ng EX, Miller MA, Jing T, Chen CH
Single cell multiplexed assay for proteolytic activity using droplet microfluidics.
Biosens Bioelectron. 2016;81:408-14 - PMID: 26995287
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN
Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis.
Inflamm Bowel Dis. 2016;22(4):880-885 - PMID: 26933751 - PMCID: PMC4792716
Secemsky EA, Butala NM, Kartoun U, Mahmood S, Wasfy JH, Kennedy KF, Shaw SY, Yeh RW
Use of Chronic Oral Anticoagulation and Associated Outcomes Among Patients Undergoing Percutaneous Coronary Intervention.
J Am Heart Assoc. 2016;5(10):ePub - PMID: 27792650 - PMCID: PMC5121523
Canali S, Core AB, Zumbrennen-Bullough KB, Merkulova M, Wang CY, Schneyer A, Pietrangelo A, Babitt JL
Activin B induces noncanonical SMAD1/5/8 signaling via BMP type I receptors in hepatocytes: evidence for a role in hepcidin induction by inflammation in male mice.
Endocrinology. 2016;:en20151747 - PMID: 26735394 - PMCID: PMC4769363
Canali S, Vecchi C, Garuti C, Montosi G, Babitt JL, Pietrangelo A
The SMAD pathway is required for hepcidin response during endoplasmic reticulum stress.
Endocrinology. 2016;:en20161258 - PMID: 27483343 - PMCID: PMC5045507
Oudin MJ, Miller MA, Klazen JA, Kosciuk T, Lussiez A, Hughes SK, Tadros J, Bear JE, Lauffenburger DA, Gertler FB
MenaINV mediates synergistic crosstalk between signaling pathways driving chemotaxis and haptotaxis.
Mol Biol Cell. 2016;27(20):3085-3094 - PMID: 27559126 - PMCID: PMC5063616
Bozhko D, Osborn EA, Rosenthal A, Verjans JW, Hara T, Kellnberger S, Wissmeyer G, Ovsepian SV, McCarthy JR, Mauskapf A, Stein AF, Jaffer FA, Ntziachristos V
Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo.
Eur Heart J Cardiovasc Imaging. 2016;18(11):1253-1261 - PMID: 28031233
Liu J, Wang W, Liu M, Su L, Zhou H, Xia Y, Ran J, Lin HY, Yang B
Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.
Cell Signal. 2016;28(12):1842-1851 - PMID: 27575743
Vinegoni C, Dubach JM, Feruglio PF, Weissleder R
Two-Photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement
IEEE J Sel Top Quantum Electron. 2016;22 (3):6801607 - PMID: 27440991 - PMCID: PMC4946648
Meng C, Liu W, Huang H, Wang Y, Chen B, Freeman GJ, Schneyer A, Lin HY, Xia Y
Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice.
Biol Reprod. 2016;94(4):78 - PMID: 26911425
Davis RW, Brannen AD, Hossain MJ, Monsma S, Bock PE, Nahrendorf M, Mead D, Lodes M, Liles MR, Panizzi P
Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains.
BMC Genomics. 2016;17(1):179 - PMID: 26940863 - PMCID: PMC4778325
Kim H, Wei Y, Lee JY, Wu Y, Zheng Y, Moskowitz MA, Chen JW
Myeloperoxidase inhibition increases neurogenesis after ischemic stroke.
J Pharmacol Exp Ther. 2016;359(2):262-272 - PMID: 27550713 - PMCID: PMC5074486
Wang CY, Babitt JL
Hepcidin regulation in the anemia of inflammation.
Curr Opin Hematol. 2016;23(3):189-197 - PMID: 26886082 - PMCID: PMC4993159
Li A, Wu Y, Linnoila J, Pulli B, Wang C, Zeller M, Ali M, Lewandrowski GK, Li J, Tricot B, Keliher E, Wojtkiewicz GR, Fulci G, Feng X, Tannous BA, Yao Z, Chen JW
Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models.
Cancer Immunol Immunther. 2016;65(12):1545-1554 - PMID: 27722909 - PMCID: PMC5101144
Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D
CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.
PLoS ONE. 2016;11(6):e0156595 - PMID: 27253518 - PMCID: PMC4890777
Vafai SB, Mevers E, Higgins KW, Fomina Y, Zhang J, Mandinova A, Newman D, Shaw SY, Clardy J, Mootha VK
Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors.
PLoS ONE. 2016;11(9):e0162686 - PMID: 27622560 - PMCID: PMC5021346
Turcotte R, Mattson JM, Wu JW, Zhang Y, Lin CP
Molecular Order of Arterial Collagen Using Circular Polarization Second-Harmonic Generation Imaging.
Biophys J. 2016;110(3):530-3 - PMID: 26806883 - PMCID: PMC4744203
Lu X, Wood DK, Higgins JM
Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension.
Biophys J. 2016;110(12):2751-8 - PMID: 27332133 - PMCID: PMC4919586
David V, Francis C, Babitt JL
Ironing out the crosstalk between FGF23 and inflammation.
Am J Physiol Renal Physiol. 2016;:ajprenal.00359.2016 - PMID: 27582104 - PMCID: PMC5283889
Mamuya FA, Cano-Peñalver JL, Li WU, Rodriguez-Puyol D, Rodríguez-Puyol M, Brown D, de Frutos S, Lu HJ
ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway.
Am J Physiol Renal Physiol. 2016;:ajprenal.00336.2016 - PMID: 27760768 - PMCID: PMC5210194
Jeun M, Park S, Lee H, Lee KH
Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles
Int J Nanomedicine. 2016;2016:11:5497–5503 - PMID: 27799772 - PMCID: PMC5085298
Turcotte R, Wu JW, Lin CP
Intravital multiphoton photoconversion with a cell membrane dye.
J Biophotonics. 2016;10(2):206-210 - PMID: 27433967
Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, Wirth DF, André V, Duarte MT, Guedes RC, J V A Dos Santos D, Rosenthal PJ, Mazitschek R, Prudêncio M, Moreira R
Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
ChemMedChem. 2016;11(19):2194-2204 - PMID: 27538856
Dorsey ER, Yvonne Chan YF, McConnell MV, Shaw SY, Trister AD, Friend SH
The Use of Smartphones for Health Research.
Acad Med. 2016;92(2):157-160 - PMID: 27119325
Castro MM, Kim B, Hill E, Fialho MC, Puga LC, Freitas MB, Breton S, Machado-Neves M
The expression patterns of aquaporin 9, vacuolar H(+)-ATPase, and cytokeratin 5 in the epididymis of the common vampire bat.
Histochem Cell Biol. 2016;147(1):39-48 - PMID: 27549752
Moss ML, Miller MA, Vujanovic N, Yoneyama T, Rasmussen FH
Fluorescent substrates for ADAM15 useful for assaying and high throughput screening.
Anal Biochem. 2016;514:42-47 - PMID: 27637923
Agarwal S, Grajo JR, Fuentes-Orrego JM, Abtahi SM, Harisinghani MG, Saini S, Hahn PF
Distinguishing hemangiomas from metastases on liver MRI performed with gadoxetate disodium: Value of the extended washout sign.
Eur J Radiol. 2016;85(3):635-40 - PMID: 26860678
Kilcoyne A, Kaplan JL, Gee MS
Inflammatory bowel disease imaging: Current practice and future directions.
World J Gastroenterol. 2016;22(3):917-32 - PMID: 26811637 - PMCID: PMC4716045
Li Y, Stone JR
The impact of splenectomy on human coronary artery atherosclerosis and vascular macrophage distribution.
Cardiovasc Pathol. 2016;25(6):453-460 - PMID: 27614166
Stats MA, Stone JR
Varying levels of small microcalcifications and macrophages in ATTR and AL cardiac amyloidosis: implications for utilizing nuclear medicine studies to subtype amyloidosis.
Cardiovasc Pathol. 2016;25(5):413-417 - PMID: 27469499
Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, Bruneval P, Buja LM, Butany J, d'Amati G, Fallon JT, Gallagher PJ, Gittenberger-de Groot AC, Gouveia RH, Kholova I, Kelly KL, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Stone JR, Suvarna SK, Tan CD, Thiene G, Veinot JP, van der Wal AC
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria.
Cardiovasc Pathol. 2016;25(3):247-257 - PMID: 27031798
Ghosh B, Zhao WN, Reis SA, Patnaik D, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ
Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.
Bioorg Med Chem Lett. 2016;26(4):1265-71 - PMID: 26804233 - PMCID: PMC4753070
Chang SY, Lo CS, Zhao XP, Liao MC, Chenier I, Bouley R, Ingelfinger JR, Chan JS, Zhang SL
Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2-HO-1 pathway in renal proximal tubular cells of transgenic mice.
J Renin Angiotensin Aldosterone Syst. 2016;17(3):ePub - PMID: 27638854
Hassanzadeh E, Glazer DI, Dunne RM, Fennessy FM, Harisinghani MG, Tempany CM
Prostate imaging reporting and data system version 2 (PI-RADS v2): a pictorial review.
Abdom Radiol. 2016;42(1):278-289 - PMID: 27522352 - PMCID: PMC5247306
Hedgire SS, Kudrimoti S, Oliveira IS, Nadkarni N, McDermott S, Hahn PF, Mino-Kenudson M, Harisinghani MG
Extranodal lymphomas of abdomen and pelvis: imaging findings and differential diagnosis.
Abdom Radiol. 2016;42(4):1096-1112 - PMID: 27866240
Diaz-Gil D, Fintelmann FJ, Molaei S, Elmi A, Hedgire SS, Harisinghani MG
Prediction of 5-year survival in advanced-stage ovarian cancer patients based on computed tomography peritoneal carcinomatosis index.
Abdom Radiol. 2016;41(11):2196-2202 - PMID: 27338731
Kilcoyne A, Price MC, McDermott S, Harisinghani MG
Imaging on nodal staging of prostate cancer.
Future Oncol. 2016;13(6):551-565 - PMID: 27785926
Pinciroli R, Mietto C, Piriyapatsom A, Chenelle CT, Thomas JG, Pirrone M, Bry L, Wojtkiewicz GR, Nahrendorf MP, Kacmarek RM, Berra L
Endotracheal Tubes Cleaned With a Novel Mechanism for Secretion Removal: A Randomized Controlled Clinical Study.
Respir Care. 2016;61(11):1431-1439 - PMID: 27460104
Zhu H, Alt C, Webb RH, Melki S, Kochevar IE
Corneal Crosslinking With Rose Bengal and Green Light: Efficacy and Safety Evaluation.
Cornea. 2016;35(9):1234-41 - PMID: 27362877
McCormack CA, Lo Gullo R, Kalra MK, Louissaint A, Stone JR
Reliability of body size measurements obtained at autopsy: impact on the pathologic assessment of the heart.
Forensic Sci Med Pathol. 2016;12(2):139-45 - PMID: 27020890
Ryu WS, Schellingerhout D, Jeong SW, Nahrendorf M, Kim DE
Association between Serum Lipid Profiles and Early Neurological Deterioration in Acute Ischemic Stroke.
J Stroke Cerebrovasc Dis. 2016;25(8):2024-30 - PMID: 27256172
Wang Z, Cho YS, Soeda T, Minami Y, Xing L, Jia H, Aguirre A, Vergallo R, Lee H, Fujimoto JG, Yu B, Jang IK
Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study.
Coron Artery Dis. 2016;27(5):350-6 - PMID: 27105047 - PMCID: PMC4912393
Perugino CA, Wallace ZS, Meyersohn N, Oliveira G, Stone JR, Stone JH
Large vessel involvement by IgG4-related disease.
Medicine (Baltimore). 2016;95(28):e3344 - PMID: 27428181 - PMCID: PMC4956774
Sager HB, Nahrendorf M
Inflammation: a trigger for acute coronary syndrome.
Q J Nucl Med Mol Imaging. 2016;60(3):185-193 - PMID: 27273431
Park KS*, Huang CH*, Lee K, Yoo YE, Castro CM, Weissleder R, Lee H
Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system
Sci Adv. 2016;2(5):e1600300 - PMID: 28861468 - PMCID: PMC5565941
Im H, Lee H, Castro CM
Challenges influencing next generation technologies for precision medicine.
Expert Rev Precis Med Drug Dev. 2016;1(2):121-123 - PMID: 28008420 - PMCID: PMC5166706
Swirski FK, Nahrendorf M, Libby P
Mechanisms of Myeloid Cell Modulation of Atherosclerosis.
Microbiol Spectr. 2016;4(4):ePub - PMID: 27726819
Clardy SM, Kohler RH, Vinegoni C, Iwamoto Y, Keliher EJ, Weissleder R
Two-photon imaging of pancreatic beta cells in real time in vivo
Technology. 2016;4(2):130-134
Kim J, Park JE, Nahrendorf M, Kim DE
Direct Thrombus Imaging in Stroke.
J Stroke. 2016;18(3):286-296 - PMID: 27733029 - PMCID: PMC5066439
Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE
Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries.
ACS Comb Sci. 2016;18(6):271-8 - PMID: 27124678 - PMCID: PMC5321554
King K, Grazette LP, Paltoo DN, McDevitt JT, Sia SK, Barrett PM, Apple FS, Gurbel PA, Weissleder R, Leeds H, Iturriaga EJ, Rao A, Adhikari B, Desvigne-Nickens P, Galis ZS, Libby P
Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group.
JACC Basic Transl Sci. 2016;1(1-2):73-86 - PMID: 26977455 - PMCID: PMC4787294
Lee H, Shin TH, Cheon J, Weissleder R
Recent Developments in Magnetic Diagnostic Systems
Chem Rev. 2015;115(19):10690-724 - PMID: 26258867
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE
Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Nature. 2015;529(7584):110-4 - PMID: 26700815 - PMCID: PMC4831574
Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M
Integrative analysis of 111 reference human epigenomes.
Nature. 2015;518(7539):317-30 - PMID: 25693563 - PMCID: PMC4530010
Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.
Nat Biotechnol. 2015;33(11):1165-72 - PMID: 26458175 - PMCID: PMC4636926
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
Cell. 2015;160(6):1246-60 - PMID: 25748654 - PMCID: PMC4380877
Liu J, Lee J, Salazar Hernandez MA, Mazitschek R, Ozcan U
Treatment of obesity with celastrol.
Cell. 2015;161(5):999-1011 - PMID: 26000480 - PMCID: PMC4768733
Garris CS, Pittet MJ
ER Stress in Dendritic Cells Promotes Cancer.
Cell. 2015;161(7):1492-3 - PMID: 26091029
Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK
Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.
Science. 2015;347(6227):1260-1265 - PMID: 25766237 - PMCID: PMC4376966
Nahrendorf M, Swirski FK
Neutrophil-macrophage communication in inflammation and atherosclerosis.
Science. 2015;349(6245):237-8 - PMID: 26185231
Langer R, Weissleder R
Nanotechnology.
JAMA. 2015;313(2):135-136 - PMID: 25585320
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
Nat Immunol. 2015;17(2):159-168 - PMID: 26642357
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Cell Stem Cell. 2015;16 (5):477-487 - PMID: 25957903 - PMCID: PMC4426344
Pfirschke C, Garris C, Pittet MJ
Common TLR5 Mutations Control Cancer Progression.
Cancer Cell. 2015;27(1):1-3 - PMID: 25584886
Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R*, Danuser G*, Mitchison TJ*
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy
Nat Methods. 2015;12(6):577-585 - PMID: 25867850 - PMCID: PMC4579269
Kong L, Tang J, Little JP, Yu Y, Lämmermann T, Lin CP, Germain RN, Cui M
Continuous volumetric imaging via an optical phase-locked ultrasound lens.
Nat Methods. 2015;12(8):759-762 - PMID: 26167641 - PMCID: PMC4551496
Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB*
Single-cell magnetic imaging using a quantum diamond microscope.
Nat Methods. 2015;12(8):736-738 - PMID: 26098019 - PMCID: PMC4521973
Dai N, Zhao L, Wrighting D, Krämer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins.
Cell Metab. 2015;21(4):609-21 - PMID: 25863250 - PMCID: PMC4663978
Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Sci Transl Med. 2015;7(288):288ra77 - PMID: 25995223 - PMCID: PMC4675670
Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamal N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R
Predicting therapeutic nano-medicine efficacy using a companion MR imaging nanoparticle.
Sci Transl Med. 2015;7:314 - PMID: 26582898 - PMCID: PMC5462466
Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M
Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Circulation. 2015;132(20):1880-90 - PMID: 26358260 - PMCID: PMC4651795
Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA
Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus"
Circulation. 2015;131(24):e531-2 - PMID: 26078375
Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA
Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo.
Eur Heart J. 2015;38(6):447-455 - PMID: 26685129
Nahrendorf M, Swirski FK
Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction
Eur Heart J. 2015;37(11):868-72 - PMID: 26351395 - PMCID: PMC4789592
Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M
Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
J Exp Med. 2015;212(4):497-512 - PMID: 25800955 - PMCID: PMC4387283
Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA
Imaging Systemic Inflammatory Networks in Ischemic Heart Disease.
J Am Coll Cardiol. 2015;65(15):1583-1591 - PMID: 25881940 - PMCID: PMC4401833
Lee K, Shao H, Weissleder R, Lee H
Acoustic Purification of Extracellular Microvesicles.
ACS Nano. 2015;9(3):2321-7 - PMID: 25672598 - PMCID: PMC4373978
Nair AV, Keliher EJ, Core AB, Brown D, Weissleder R
Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo.
ACS Nano. 2015;9(4):3641-53 - PMID: 25790730 - PMCID: PMC4414893
Nahrendorf M, Swirski FK
Lifestyle Effects on Hematopoiesis and Atherosclerosis.
Circ Res. 2015;116(5):884-894 - PMID: 25722442 - PMCID: PMC4347940
Courties G, Herisson F, Sager H, Heidt T, Ye Y, Ying W, Sun Y, Severe N, Dutta P, Scharff J, Scadden D, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M
Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells.
Circ Res. 2015;116(3):407-17 - PMID: 25362208 - PMCID: PMC4312511 - Cover
Konishi M, Erdem SS, Weissleder R, Lichtman AH, McCarthy J, Libby P
Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis.
Circ Res. 2015;117(6):502-12 - PMID: 26199323 - PMCID: PMC4553143
Ye YX, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz GR, Iwamoto Y, Tang J, Perez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, Weissleder R, Tawakol A, Dubey S, Belanger AP, Di Carli MF, Swirski FK, Kjær A, Mulder W, Nahrendorf M
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circ Res. 2015;117(10):835-45 - PMID: 26394773 - PMCID: PMC4619168 - Cover
Ryan RJ, Drier Y, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE
Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.
Cancer Discov. 2015;5(10):1058-71 - PMID: 26229090 - PMCID: PMC4592453
Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M
Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.
Nat Commun. 2015;6:8803 - PMID: 26541940 - PMCID: PMC4638135
Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H*, Weissleder R*
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Nat Commun. 2015;6:6999 - PMID: 25959588 - PMCID: PMC4430127
Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.
Nat Commun. 2015;6:8692 - PMID: 26503691 - PMCID: PMC4711745
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW
ADAM8 as a drug target in pancreatic cancer.
Nat Commun. 2015;6:6175 - PMID: 25629724 - PMCID: PMC5014123
Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.
Nat Commun. 2015;6:7029 - PMID: 25967391 - PMCID: PMC4435621
Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL
Noninvasive imaging of immune responses.
Proc Natl Acad Sci U S A. 2015;112(19):6146-51 - PMID: 25902531 - PMCID: PMC4434737
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK
AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Proc Natl Acad Sci U S A. 2015;112(32):E4418-27 - PMID: 26216943 - PMCID: PMC4538667
Di Caprio G, Stokes C, Higgins JM, Schonbrun E
Single-cell measurement of red blood cell oxygen affinity.
Proc Natl Acad Sci U S A. 2015;112(32):9984-9 - PMID: 26216973 - PMCID: PMC4538663
Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C
Population dynamics of islet-infiltrating cells in autoimmune diabetes.
Proc Natl Acad Sci U S A. 2015;112(5):1511-6 - PMID: 25605891 - PMCID: PMC4321317
Weissleder R, Nahrendorf M
Advancing biomedical imaging
Proc Natl Acad Sci U S A. 2015;112(47):14424-8 - PMID: 26598657 - PMCID: PMC4664297
Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C Mathis D, Weissleder R
Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
Proc Natl Acad Sci U S A. 2015;112(7):2139-44 - PMID: 25650428 - PMCID: PMC4343112
Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H*
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone
Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451
Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
eLife. 2015;4:ePub - PMID: 25998054 - PMCID: PMC4441007
Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression.
Blood. 2015;126(16):1930-9 - PMID: 26320100 - PMCID: PMC4608240
Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R
On chip analysis of CNS lymphoma in cerebrospinal fluid.
Theranostics. 2015;5(8):796-804 - PMID: 26000053 - PMCID: PMC4440438
Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA
Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735
Kim JY, Ryu JH, Schellingerhout D, Sun IC, Lee SK, Jeon S, Kim J, Kwon IC, Nahrendorf M, Ahn CH, Kim K, Kim DE
Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.
Theranostics. 2015;5(10):1098-114 - PMID: 26199648 - PMCID: PMC4508499
Tesfay L, Clausen KA, Kim JW, Hedge P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV
Hepcidin regulation in prostate and its disruption in prostate cancer.
Cancer Res. 2015;75(11):2254-63 - PMID: 25858146 - PMCID: PMC4454355
Vinegoni C, Aguirre AD, Lee S, Weissleder R
Imaging the beating heart in the mouse using intravital microscopy techniques.
Nat Protoc. 2015;10(11):1802-1819 - PMID: 26492138 - PMCID: PMC5380003
David V, Martin A, Isakova T, Spaulding C, Qi L, Ramirez V, Zumbrennen-Bullough KB, Sun CC, Lin HY, Babitt JL, Wolf M
Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production.
Kidney Int. 2015;89(1):135-46 - PMID: 26535997 - PMCID: PMC4854810
Koo H, Choi M, Kim E, Hahn SK, Weissleder R, Yun SH
Bioorthogonal Click Chemistry-Based Synthetic Cell Glue.
Small. 2015;11(48):6458-66 - PMID: 26768353 - PMCID: PMC5556392 - Cover
Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H
Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease.
Hum Mol Genet. 2015;24(21):6254-63 - PMID: 26310624 - PMCID: PMC4599680
Pulli B, Ali M, Iwamoto Y, Zeller MW, Schob S, Linnoila JJ, Chen JW
Myeloperoxidase - Hepatocyte - Stellate Cell Crosstalk Promotes Hepatocyte Injury and Fibrosis in Experimental NASH.
Antioxid Redox Signal. 2015;23(16):1255-1269 - PMID: 26058518 - PMCID: PMC4677570
Desai RM, Koshy ST, Hilderbrand SA, Mooney DJ, Joshi NS
Versatile click alginate hydrogels crosslinked via tetrazine-norbornene chemistry.
Biomaterials . 2015;50:30-7 - PMID: 25736493
Levy O, Mortensen LJ, Boquet G, Tong Z, Perrault C, Benhamou B, Zhang J, Stratton T, Han E, Safaee H, Musabeyezu J, Yang Z, Multon MC, Rothblatt J, Deleuze JF, Lin CP, Karp JM
A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells.
Cell Rep. 2015;10(8):1261-1268 - PMID: 25732817 - PMCID: PMC4361231
He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK
Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.
Circ Heart Fail. 2015;8(5):980-7 - PMID: 26232205 - PMCID: PMC4568849
Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJ, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J
Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling.
JACC Cardiovasc Interv. 2015;8(2):355-63 - PMID: 25596792 - PMCID: PMC5645299
Nahrendorf M, Dutta P
Targeting splenic hematopoietic stem cells in cardiovascular disease.
Oncotarget. 2015;6(24):19918-9 - PMID: 26343366 - PMCID: PMC4652955
Tong T, Yang Z, Chen JW, Zhu J, Yao Z
Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma.
Oncotarget. 2015;6(31):32257-32265 - PMID: 26337080 - PMCID: PMC4741675
Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW
Myeloperoxidase Nuclear Imaging for Epileptogenesis.
Radiology. 2015;:141922 - PMID: 26397127 - PMCID: PMC4770943
Libby P, King K
Biomarkers: A Challenging Conundrum in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2015;35(12):2491-5 - PMID: 26543097
Dutta P, Nahrendorf M
Monocytes in Myocardial Infarction.
Arterioscler Thromb Vasc Biol. 2015;35(5):1066-70 - PMID: 25792449 - PMCID: PMC4409536
Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D
Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.
Crit Care Med. 2015;44(5):e241-52 - PMID: 26509319 - PMCID: PMC4833510
Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS,
Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study.
Am J Transplant. 2015;16(1):121-36 - PMID: 26260101 - PMCID: PMC4948061
Siddiquee Z, Smith RN, Stone JR
An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis.
Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884
Nahrendorf M, Swirski FK
PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction.
JACC Cardiovasc Imaging. 2015;8(12):1427-9 - PMID: 26699111
Gonçalves I, den Ruijter H, Nahrendorf M, Pasterkamp G
Detecting the vulnerable plaque in patients.
J Intern Med. 2015;278(5):520-30 - PMID: 26306911
Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH
Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.
Lab Chip. 2015;15(4):1153-9 - PMID: 25553996
Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R
Advances in measuring single-cell pharmacokinetics and pharmacology in vivo.
Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932
Hong S, Carlson J, Lee H, Weissleder R
Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking.
Adv Healthc Mater. 2015;5(4):421-426 - PMID: 26688173 - PMCID: PMC4811597
Park KS, Charles RC, Ryan ET, Weissleder R*, Lee H*
Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease
Chem Eur J. 2015;21(46):16359-63 - PMID: 26420633 - PMCID: PMC4816641
Clardy SM, James F. Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R
Rapid, high efficiency isolation of pancreatic ß-cells
Sci Rep. 2015;5:13681 - PMID: 26330153 - PMCID: PMC4557033
Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA
Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.
Sci Rep. 2015;5:15150 - PMID: 26477568 - PMCID: PMC4609913
Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R
Single cell resolution in vivo imaging of DNA damage following PARP inhibition
Sci Rep. 2015;5:10129 - PMID: 25984718 - PMCID: PMC4434991
Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA
Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging.
Sci Rep. 2015;5:17220 - PMID: 26610702 - PMCID: PMC4661695
Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, Hanna RN, Wu R, Swirski FK, Geissmann F, Hedrick CC
The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus.
Sci Rep. 2015;5:10055 - PMID: 26091486 - PMCID: PMC4473761
Merkulova M, Păunescu TG, Azroyan A, Marshansky V, Breton S, Brown D
Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.
Sci Rep. 2015;5:14827 - PMID: 26442671 - PMCID: PMC4595830
Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M
Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation.
J Immunol. 2015;195(3):1282-92 - PMID: 26085679 - PMCID: PMC4506852
Iaconelli J, Huang JH, Berkovitch SS, Chattopadhyay S, Mazitschek R, Schreiber SL, Haggarty SJ, Karmacharya R
HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells.
ACS Chem Biol. 2015;10(3):883-90 - PMID: 25546293 - PMCID: PMC4372110
Hulsmans M, Sam F, Nahrendorf M
Monocyte and macrophage contributions to cardiac remodeling.
J Mol Cell Cardiol. 2015;93:149-55 - PMID: 26593722 - PMCID: PMC4846552
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ
Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Inflamm Bowel Dis. 2015;21(11):2507-2514 - PMID: 26241000 - PMCID: PMC4615315
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I
Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort.
Inflamm Bowel Dis. 2015;22(1):151-158 - PMID: 26332313 - PMCID: PMC4772891
Guan Y, Meurer M, Raghavan S, Rebane A, Lindquist JR, Santos S, Kats I, Davidson MW, Mazitschek R, Hughes TE, Drobizhev M, Knop M, Shah JV
Live Cell Multi-Photon Fluorescence Correlation Spectroscopy with an Improved Large Stokes Shift Fluorescent Protein.
Mol Biol Cell. 2015;26(11):2054-66 - PMID: 25877871 - PMCID: PMC4472016
Park YI, Im H, Weissleder R, Lee H
Nanostar clustering improves the sensitivity of plasmonic assays.
Bioconjug Chem. 2015;26(8):1470-1474 - PMID: 26102604 - PMCID: PMC5292976
Kim E, Yang K, Kohler R, Dubach JM, Mikula H, Weissleder R
Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression.
Bioconjug Chem. 2015;26(8):1513-1518 - PMID: 26017814 - PMCID: PMC4772718
Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R
Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies.
Bioconjug Chem. 2015;27(1):257-63 - PMID: 26684717 - PMCID: PMC4858350
Pang Y, Tsigkou O, Spencer JA, Lin CP, Neville C, Grottkau B
Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing.
Tissue Eng Part C Methods. 2015;21(10):1025-1031 - PMID: 25962617 - PMCID: PMC4593976
Im H, Shao H, Weissleder R, Castro CM, Lee H
Nano-plasmonic exosome diagnostics.
Expert Rev Mol Diagn. 2015;:1-9 - PMID: 25936957 - PMCID: PMC4675626
Whitley MJ, Weissleder R, Kirsch DG
Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer.
Semin Radiat Oncol. 2015;25(4):313-21 - PMID: 26384279 - PMCID: PMC4575408
Kim B, Breton S
The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis.
Biol Reprod. 2015;94(1):22 - PMID: 26658708 - PMCID: PMC4809559
Patel H, Patel H, Higgins JM
Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease.
Am J Hematol. 2015;90(5):422-8 - PMID: 25691355 - PMCID: PMC4717489
Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T
Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
J Am Med Inform Assoc. 2015;22(5):993-1000 - PMID: 25929596 - PMCID: PMC4986664
Rice WL, Li W, Mamuya F, McKee M, Păunescu TG, Lu HA
Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture.
PLoS ONE. 2015;10(7):e0131719 - PMID: 26147297 - PMCID: PMC4493001
Azroyan A, Cortez-Retamozo V, Bouley R, Liberman R, Ruan YC, Kiselev E, Jacobson KA, Pittet MJ, Brown D, Breton S
Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor.
PLoS ONE. 2015;10(3):e0121419 - PMID: 25799465 - PMCID: PMC4370445
Rotem A, Ram O, Shoresh N, Sperling RA, Schnall-Levin M, Zhang H, Basu A, Bernstein BE, Weitz DA
High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics.
PLoS ONE. 2015;10(5):e0116328 - PMID: 26000628 - PMCID: PMC4441486
Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.
PLoS ONE. 2015;10(8):e0136651 - PMID: 26301417 - PMCID: PMC4547801
Chung HJ, Pellegrini KL, Chung J, Wanigasuriya K, Jayawardene I, Lee K, Lee H, Vaidya VS, Weissleder R
Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury.
PLoS ONE. 2015;10(7):e0133417 - PMID: 26186708 - PMCID: PMC4506142
Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M
Engineered Trehalose Permeable to Mammalian Cells.
PLoS ONE. 2015;10(6):e0130323 - PMID: 26115179 - PMCID: PMC4482662
Kessinger CW, Kim JW, Henke PK, Thompson B, McCarthy JR, Hara T, Sillesen M, Margey RJ, Libby P, Weissleder R, Lin CP, Jaffer FA
Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring.
PLoS ONE. 2015;10(2):e0116621 - PMID: 25680183 - PMCID: PMC4334538
Da Silva N, Barton CR
Macrophages and dendritic cells in the post-testicular environment.
Cell Tissue Res. 2015;363(1):97-104 - PMID: 26337514 - PMCID: PMC4703462 - Cover
Herak-Kramberger CM, Breljak D, Ljubojević M, Matokanovic M, Lovric M, Rogic D, Brzica H, Vrhovac I, Karaica D, Micek V, Ivkovic Dupor J, Brown D, Sabolic I
Sex-dependent expression of water channel AQP1 along the rat nephron.
Am J Physiol Renal Physiol. 2015;:ajprenal.00368.2014 - PMID: 25656365 - PMCID: PMC4398837
Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ
Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells.
Am J Physiol Renal Physiol. 2015;:ajprenal.00152.2015 - PMID: 26290367 - PMCID: PMC4609919
Heng E, Stone JR, Kim JB, Lee H, MacGillivray TE, Sundt TM
Comparative Histology of Aortic Dilatation Associated With Bileaflet Versus Trileaflet Aortic Valves.
Ann Thorac Surg. 2015;100(6):2095-2101 - PMID: 26338050
Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.
Eur J Med Chem. 2015;102:320-333 - PMID: 26295174
Chousterman BG, Swirski FK
Innate Response Activator B cells: origins and functions.
Int Immunol. 2015;27(10):537-41 - PMID: 25957266 - PMCID: PMC4693688
Ullal AV, Weissleder R
Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells.
Methods Mol Biol. 2015;1346:47-54 - PMID: 26542714
Brettman AD, Tan PH, Tran K, Shaw SY
Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles.
Methods Mol Biol. 2015;1263:15-27 - PMID: 25618333 - PMCID: PMC4357233
Davis RW, Eggleston H, Johnson F, Nahrendorf M, Bock PE, Peterson T, Panizzi P
In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model.
Mol Imaging Biol. 2015;17(6):793-801 - PMID: 25921659 - PMCID: PMC4807872
Carlucci G, Carney B, Brand C, Kossatz S, Irwin CP, Carlin SD, Keliher EJ, Weber W, Reiner T
Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma.
Mol Imaging Biol. 2015;17(6):848-55 - PMID: 25895168 - PMCID: PMC4609241
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Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis.
Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361
Joseph P, Ishai A, MacNabb M, Abdelbaky A, Lavender ZR, Ruskin J, Nahrendorf M, Tawakol A
Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation.
Int J Cardiovasc Imaging. 2015;32(1):113-119 - PMID: 26411879 - PMCID: PMC4730873
Corey KE, Kartoun U, Zheng H, Shaw SY
Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.
Dig Dis Sci. 2015;61(3):913-9 - PMID: 26537487 - PMCID: PMC4761309
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Exploring the role of mononuclear phagocytes in the epididymis.
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Regulation of epithelial function, differentiation, and remodeling in the epididymis.
Asian J Androl. 2015;18(1):3-9 - PMID: 26585699 - PMCID: PMC4736353
Li Y, Zhao T, Liu B, Halaweish I, Mazitschek R, Duan X, Alam HB
Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model.
J Trauma Acute Care Surg. 2015;78(2):378-85 - PMID: 25757125 - PMCID: PMC4357277
Kevin Li-Chun H, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW
Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis.
J Neuroimmunol. 2015;287:36-42 - PMID: 26439960 - PMCID: PMC4595933
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Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.
Cardiovasc Pathol. 2015;24(5):267-278 - PMID: 26051917
Huck A, Pozdnyakova O, Brunner A, Higgins JM, Fathi AT, Hasserjian RP
Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia.
Leuk Res. 2015;39(10):1034-40 - PMID: 26220865
Framme C, Walter A, Berger L, Prahs P, Alt C, Theisen-Kunde D, Kowal J, Brinkmann R
Selective Retina Therapy in Acute and Chronic-Recurrent Central Serous Chorioretinopathy.
Ophthalmologica. 2015;234(4):177-188 - PMID: 26368551
Lo Gullo R, Mishra S, Lira DA, Padole A, Otrakji A, Khawaja RD, Pourjabbar S, Singh S, Shepard JO, Digumarthy SR, Kalra MK, Stone JR
Quantification of interstitial fluid on whole body CT: comparison with whole body autopsy.
Forensic Sci Med Pathol. 2015;11(4):488-496 - PMID: 26541472
Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY
Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys.
BMC Nephrol. 2015;16(1):119 - PMID: 26227484 - PMCID: PMC4521488
Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK
Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents.
Coron Artery Dis. 2015;27(1):19-28 - PMID: 26554662 - PMCID: PMC4679565
Liang JS, Lee SP, Pulli B, Chen JW, Kao SC, Tsang YM, Hsieh KL
Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study.
Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405
Vinegoni C, Lee S, Aguirre AD, Weissleder R
New techniques for motion-artifact-free in vivo cardiac microscopy.
Front Physiol. 2015;6:147 - PMID: 26029116 - PMCID: PMC4428079
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Acta Neuropathol Commun. 2015;3(1):22 - PMID: 25853389 - PMCID: PMC4382927
Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H
The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.
ACS Cent Sci. 2015;1(3):142-147 - PMID: 26955657 - PMCID: PMC4778250
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Sci Adv. 2015;1(3):ePub - PMID: 26295063 - PMCID: PMC4539616
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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes.
New Engl J Med. 2014;371(26):2488-2498 - PMID: 25426837 - PMCID: PMC4306669
Baggett MV, Turbett SE, Schwartzenberg SS, Stone JR
Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure.
New Engl J Med. 2014;370(7):651-60 - PMID: 24521112
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Direct measurement of local oxygen concentration in the bone marrow of live animals.
Nature. 2014;508(7495):269-73 - PMID: 24590072 - PMCID: PMC3984353
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY
ABCB5 is a limbal stem cell gene required for corneal development and repair.
Nature. 2014;511(7509):353-7 - PMID: 25030174 - PMCID: PMC4246512
Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE
Genetic and epigenetic fine mapping of causal autoimmune disease variants.
Nature. 2014;518(7539):337-43 - PMID: 25363779 - PMCID: PMC4336207
Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov AM, Epstein C, Rinn JL, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A
Dissecting neural differentiation regulatory networks through epigenetic footprinting.
Nature. 2014;518(7539):355-9 - PMID: 25533951 - PMCID: PMC4336237
Weissleder R, Nahrendorf M, Pittet MJ
Imaging macrophages with nanoparticles.
Nat Mater. 2014;13(2):125-38 - PMID: 24452356 - Cover
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Nat Genet. 2014;46(4):364-70 - PMID: 24584072 - PMCID: PMC4086945
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Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947
Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells.
Cell. 2014;157(3):580-94 - PMID: 24726434 - PMCID: PMC4004670
Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.
Cell. 2014;158(5):1110-22 - PMID: 25171411 - PMCID: PMC4149753
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In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight.
Nat Nanotechnol. 2014;9(8):648-55 - PMID: 24813696 - PMCID: PMC4207430
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.
Science. 2014;344(6190):1396-401 - PMID: 24925914 - PMCID: PMC4123637
Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL
Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors.
Science. 2014;344(6184):630-4 - PMID: 24797482 - PMCID: PMC4123747
Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M
Chronic variable stress activates hematopoietic stem cells
Nature Med. 2014;20(7):754-758 - PMID: 24952646 - PMCID: PMC4087061
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN
EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma.
Cancer Cell. 2014;26(5):668-81 - PMID: 25453903 - PMCID: PMC4492343
Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R
Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin
Sci Transl Med. 2014;6 (261):261ra152 - PMID: 25378644 - PMCID: PMC4330962
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Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates
Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113 - PMCID: PMC4063286
Mulder WJ, Jaffer FA, Fayad ZA, Nahrendorf M
Imaging and Nanomedicine in Inflammatory Atherosclerosis.
Sci Transl Med. 2014;6(239):239sr1 - PMID: 24898749 - PMCID: PMC4110972 - Cover
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MARCOing Monocytes for Elimination.
Sci Transl Med. 2014;6(219):219fs4 - PMID: 24431109 - PMCID: PMC4374341
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Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Nat Neurosci. 2014;17(9):1156-1163 - PMID: 25129075 - PMCID: PMC4292795
Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA
FDG-PET/CT Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus.
Circulation. 2014;130(13):1044-52 - PMID: 25070665 - PMCID: PMC4174982
Kroll MW, Lakkireddy DR, Stone JR, Luceri RM
TASER Electronic Control Devices and Cardiac Arrests: Coincidental or Causal?
Circulation. 2014;129(1):93-100 - PMID: 24396012
Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity.
Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655
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Silencing of CCR2 in myocarditis.
Eur Heart J. 2014;36(23):1478-88 - PMID: 24950695 - PMCID: PMC4465633
Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ
Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study.
Eur Heart J. 2014;35(42):2972-9 - PMID: 24742886 - PMCID: PMC4223610
Attanasio C, Nord AS, Zhu Y, Blow MJ, Biddie SC, Mendenhall EM, Dixon J, Wright CA, Hosseini R, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Afzal V, Ren B, Bernstein B, Rubin E, Visel A, Pennacchio L
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.
Genome Res. 2014;24(6):920-9 - PMID: 24752179 - PMCID: PMC4032856
Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis.
J Exp Med. 2014;211(6):1243-56 - PMID: 24821911 - PMCID: PMC4042649
Taqueti VR, Nahrendorf M, Di Carli MF
Translational molecular imaging: repurposing an old technique to track cell migration into human atheroma.
J Am Coll Cardiol. 2014;64(10):1030-2 - PMID: 25190239
Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R
Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging.
Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131
Dutta P, Nahrendorf M
Regulation and consequences of monocytosis.
Immunol Rev. 2014;262(1):167-78 - PMID: 25319334 - PMCID: PMC4203415
Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire C, Chen JW, Tannous BA, Breakefield XO
Dynamic Biodistribution of Extracellular Vesicles In Vivo Using a Multimodal Imaging Reporter.
ACS Nano. 2014;8(1):483-94 - PMID: 24383518 - PMCID: PMC3934350
Heidt T, Courties G, Dutta P, Sager H, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M
Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction.
Circ Res. 2014;115(2):284-95 - PMID: 24786973 - PMCID: PMC4082439
Swirski FK, Nahrendorf M
Do vascular smooth muscle cells differentiate to macrophages in atherosclerotic lesions?
Circ Res. 2014;115(7):605-6 - PMID: 25214571 - PMCID: PMC4166538
Nahrendorf M, Swirski FK
Regulating repair: regulatory T cells in myocardial infarction.
Circ Res. 2014;115(1):7-9 - PMID: 24951758 - PMCID: PMC4094354
Nahrendorf M, Swirski FK
Fluorescent leukocytes enter plaque on the microscope stage.
Circ Res. 2014;114(5):740-1 - PMID: 24577957 - PMCID: PMC3957183
Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherrer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium.
Circ Res. 2014;114(10):1611-22 - PMID: 24625784 - PMCID: PMC4017349
Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF
A genomic and evolutionary approach reveals non-genetic drug resistance in malaria.
Genome Biol. 2014;15(11):511 - PMID: 25395010 - PMCID: PMC4272547
Eda H, Santo L, Cirstea DD, Yee AJ, Scullen TA, Nemani N, Mishima Y, Waterman PR, Arastu-Kapur S, Evans E, Singh J, Kirk CJ, Westlin WF, Raje NS
A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
Leukemia. 2014;28(9):1892-901 - PMID: 24518207
Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, Yuan J, Ware C, MacLean J, Garrett-Engele PW, Kluk M, Laskey J, Haines BB, Moskaluk C, Zawel L, Fawell S, Gilliland G, Zhang T, Kremer B, Knoechel B, Bernstein BE, Pear WS, Liu XS, Aster JC, Sathyanarayanan S
Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma.
Cancer Discov. 2014;4(10):1154-67 - PMID: 25104330 - PMCID: PMC4184927
Lee SK, Mortensen LJ, Lin CP, Tung CH
An authentic imaging probe to track cell fate from beginning to end.
Nat Commun. 2014;5:5216 - PMID: 25323442 - PMCID: PMC4852472
Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation.
Nat Commun. 2014;5:3065 - PMID: 24445279 - PMCID: PMC4001802
Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R
In vivo imaging of specific drug-target binding at subcellular resolution.
Nat Commun. 2014;5:3946 - PMID: 24867710 - PMCID: PMC4362617
Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B
Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.
Nat Commun. 2014;5:5662 - PMID: 25489927 - PMCID: PMC4261930
Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D
Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature.
Proc Natl Acad Sci U S A. 2014;111(31):11419-24 - PMID: 25049388 - PMCID: PMC4128122
Aguirre AD, Vinegoni C, Sebas M, Weissleder R
Intravital imaging of cardiac function at the single-cell level.
Proc Natl Acad Sci U S A. 2014;111(31):11257-62 - PMID: 25053815 - PMCID: PMC4128110
Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut.
Proc Natl Acad Sci U S A. 2014;111(18):6696-701 - PMID: 24753589 - PMCID: PMC4020091
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC
Defining functional DNA elements in the human genome.
Proc Natl Acad Sci U S A. 2014;111(17):6131-6138 - PMID: 24753594 - PMCID: PMC4035993
Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
Proc Natl Acad Sci U S A. 2014;111(46):E4946-53 - PMID: 25369933 - PMCID: PMC4246292
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC
Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease.
Proc Natl Acad Sci U S A. 2014;111(33):E3366 - PMID: 25275169 - PMCID: PMC4143047
Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D
Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
eLife. 2014;3:e04631 - PMID: 25407682 - PMCID: PMC4270084 - Cover
Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Del Toro R, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192
Babitt JL, Lin HY
BuMPing iron with modified heparins.
Blood. 2014;123(10):1440-1 - PMID: 24627550 - PMCID: PMC3945857
Yoon YI, Kwon YS, Cho HS, Heo SH, Park KS, Park SG, Lee SH, Hwang SI, Kim YI, Jae HJ, Ahn GJ, Cho YS, Lee H*, Lee HJ*, Yoon TJ*
Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System
Theranostics. 2014;4(11):1133-1144
Chan CT, Qi J, Smith W, Paranal R, Mazitschek R, West N, Reeves R, Chiosis G, Schreiber SL, Bradner JE, Paulmurugan R, Gambhir SS
Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase (HDAC) Inhibitors by Multimodality Molecular Imaging in Living Subjects.
Cancer Res. 2014;74(24):7475-86 - PMID: 25320008 - PMCID: PMC4315624
Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L
Harnessing the Intestinal Microbiome for Optimal Therapeutic Immunomodulation.
Cancer Res. 2014;74(16):4217-4221 - PMID: 25074615
Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L
Gut microbiome and anticancer immune response: really hot Sh*t!
Cell Death Differ. 2014;22(2):199-214 - PMID: 24832470 - PMCID: PMC4291500
Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Desphande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman JA, Bardeesy N
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer.
Clin Cancer Res. 2014;21(2):396-404 - PMID: 25348516 - PMCID: PMC4447091
Teo GS, Yang Z, Carman CV, Karp JM, Lin CP
Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association with Platelets and Neutrophils.
Stem Cells. 2014;33(1):265-277 - PMID: 25263183 - PMCID: PMC4270897
Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis.
Sci Signal. 2014;7(348):ra100 - PMID: 25336613 - PMCID: PMC4300109
Ghazani A, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R
Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance.
Nanomedicine. 2014;10 :661-668 - PMID: 24200523 - PMCID: PMC3966960
Aranda F, Bloy N, Pesquet J, Petit B, Chaba K, Sauvat A, Kepp O, Khadra N, Enot D, Pfirschke C, Pittet M, Zitvogel L, Kroemer G, Senovilla L
Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer.
Oncogene. 2014;34(23):3053-62 - PMID: 25065595
Lan YY, Londoño D, Bouley R, Rooney MS, Hacohen N
Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy.
Cell Rep. 2014;9(1):180-92 - PMID: 25284779 - PMCID: PMC4555847
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases.
Clin Gastroenterol Hepatol. 2014;12(11):1905-1910 - PMID: 24632349 - PMCID: PMC4162859
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2014;12(8):1342-1348.e1 - PMID: 24407106 - PMCID: PMC4085150
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2014;13(2):322-329.e1 - PMID: 25041865 - PMCID: PMC4297589
Kim E, Yang KS, Giedt RJ, Weissleder R
Red Si-rhodamine drug conjugates enable imaging in GFP cells.
Chem Commun. 2014;50(34):4504-7 - PMID: 24663433 - PMCID: PMC4028821
Castro CM, Im H, Le C, Lee H, Weissleder R, Birrer MJ
Exploring alternative ovarian cancer biomarkers using innovative nanotechnology strategies.
Cancer Metastasis Rev. 2014;34(1):75-82 - PMID: 25543192 - PMCID: PMC5474936
Pulli B, Bure L, Wojtkiewicz GR, Iwamoto Y, Ali M, Li D, Schob S, Li-Chun Hsieh K, Jacobs AH, Chen JW
Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model.
Radiology. 2014;:141495 - PMID: 25494298 - PMCID: PMC4455671
Hilgendorf I, Swirski FK, Robbins CS
Monocyte Fate in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2014;35(2):272-9 - PMID: 25538208
Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A
Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.
JACC Cardiovasc Imaging. 2014;8(2):121-30 - PMID: 25577441
Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R*, Lee H*
Magnetic sensing technology for molecular analyses.
Lab Chip. 2014;14(14):2385-97 - PMID: 24887807 - PMCID: PMC4098149
Frantz S, Nahrendorf M
Cardiac macrophages and their role in ischemic heart disease.
Cardiovasc Res. 2014;102(2):240-8 - PMID: 24501331 - PMCID: PMC3989449
Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway.
J Cell Sci. 2014;127(Pt 20):4396-408 - PMID: 25107366 - PMCID: PMC4197086 - Cover
Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R*
Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040
Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P
Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata.
Circ Cardiovasc Imaging. 2014;7(6):920-929 - PMID: 25170063 - PMCID: PMC4237630
Nahrendorf M, Swirski FK
Imaging systemic inflammation in patients with acute myocardial infarction.
Circ Cardiovasc Imaging. 2014;7(5):762-4 - PMID: 25227235
Roussakis E, Spencer JA, Lin CP, Vinogradov SA
Two-Photon Antenna-Core Oxygen Probe with Enhanced Performance.
Anal Chem. 2014;86(12):5937-45 - PMID: 24848643 - PMCID: PMC4066907
Thurber G, Reiner T, Yang K, Kohler R, Weissleder R
Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors.
Mol Cancer Ther. 2014;13(4):986-95 - PMID: 24552776 - PMCID: PMC3981972
Lee S, Vinegoni C, Sebas M, Weissleder R
Automated motion artifact removal for intravital microscopy, without a priori information.
Sci Rep. 2014;4:4507 - PMID: 24676021 - PMCID: PMC3968488
Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R
Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor.
Sci Rep. 2014;4:4782 - PMID: 24759210 - PMCID: PMC3998017
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S
Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity.
ACS Chem Biol. 2014;9(4):1061 - PMID: 22724584
Forghani R, Kim HJ, Wojtkiewicz GR, Bure L, Wu Y, Hayase M, Wei Y, Zheng Y, Moskowitz MA, Chen JW
Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke.
J Cereb Blood Flow Metab. 2014;35(3):485-93 - PMID: 25515211 - PMCID: PMC4348390
Swirski FK, Hilgendorf I, Robbins CS
From proliferation to proliferation: monocyte lineage comes full circle.
Semin Immunopathol. 2014;36(2):137-48 - PMID: 24435095 - PMCID: PMC3991755
Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes.
Mol Cell Biol. 2014;34(14):2773 - PMID: 24951669 - PMCID: PMC4097671
Malka R, Delgado FF, Manalis SR, Higgins JM
In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells.
PLoS Comput Biol. 2014;10(10):e1003839 - PMID: 25299941 - PMCID: PMC4191880
Xu Y, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW
The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis.
J Lipid Res. 2014;56(2):266-76 - PMID: 25528754 - PMCID: PMC4306681
Jun HJ, Roy J, Smith TB, Wood LB, Lane K, Woolfenden S, Punko D, Bronson RT, Haigis KM, Breton S, Charest A
ROS1 Signaling Regulates Epithelial Differentiation in the Epididymis.
Endocrinology. 2014;:en20141341 - PMID: 24971615 - PMCID: PMC4138574
Zumbrennen-Bullough K, Wu Q, Core AB, Canali S, Chen W, Theurl I, Meynard D, Babitt JL
MicroRNA-130a is upregulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription.
J Biol Chem. 2014;289(34):23796-808 - PMID: 25002578 - PMCID: PMC4156078
Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T
Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.
Hum Genet. 2014;133(11):1369-82 - PMID: 25062868 - PMCID: PMC4185241
Courtis AM, Santos SA, Guan Y, Hendricks JA, Ghosh B, Szantai-Kis DM, Reis SA, Shah JV, Mazitschek R
Monoalkoxy BODIPYs - A Fluorophore Class for Bioimaging.
Bioconjug Chem. 2014;25(6):1043-51 - PMID: 24797834 - PMCID: PMC4215867
Sprachman M, Laughney A, Kohler R, Weissleder R
In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor.
Bioconjug Chem. 2014;25(6):1137-42 - PMID: 24806886 - PMCID: PMC4098115
Giedt RJ, Sprachman M, Yang K, Weissleder R
Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates.
Bioconjug Chem. 2014;25(11):2081-2085 - PMID: 25333750 - PMCID: PMC4240345
Brand C, Abdel-Atti D, Zhang Y, Carlin S, Clardy SM, Keliher EJ, Weber WA, Lewis JS, Reiner T
In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent.
Bioconjug Chem. 2014;25(7):1323-30 - PMID: 24856928 - PMCID: PMC4215873
Marshansky V, Rubinstein JL, Grüber G
Eukaryotic V-ATPase: Novel Structural Findings and Functional Insights.
Biochim Biophys Acta. 2014;1837(6):857-879 - PMID: 24508215
Păunescu TG, Shum WW, Huynh C, Lechner L, Goetze B, Brown D, Breton S
High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa.
Mol Hum Reprod. 2014;20(10):929-37 - PMID: 25015675 - PMCID: PMC4172170
Pittet MJ, Nahrendorf M, Swirski FK
The journey from stem cell to macrophage.
Ann N Y Acad Sci. 2014;1319(1):1-18 - PMID: 24673186 - PMCID: PMC4074243
Michot C, Le Goff C, Mahaut C, Afenjar A, Brooks AS, Campeau PM, Destree A, Di Rocco M, Donnai D, Hennekam R, Heron D, Jacquemont S, Kannu P, Lin AE, Manouvrier-Hanu S, Mansour S, Marlin S, McGowan R, Murphy H, Raas-Rothschild A, Rio M, Simon M, Stolte-Dijkstra I, Stone JR, Sznajer Y, Tolmie J, Touraine R, van den Ende J, Van der Aa N, van Essen T, Verloes A, Munnich A, Cormier-Daire V
Myhre and LAPS syndromes: clinical and molecular review of 32 patients.
Eur J Hum Genet. 2014;22(11):1272-7 - PMID: 24424121 - PMCID: PMC4200423
Vinegoni C, Lee S, Feruglio PF, Weissleder R
Advanced Motion Compensation Methods for Intravital Optical Microscopy.
IEEE J Sel Top Quantum Electron. 2014;20(2):ePub - PMID: 24273405 - PMCID: PMC3832946
Kim B, Roy J, Shum WW, Da Silva N, Breton S
Role of Testicular Luminal Factors on Basal Cell Elongation and Proliferation in the Mouse Epididymis.
Biol Reprod. 2014;92(1):9 - PMID: 25411392 - PMCID: PMC4434934
Shum WW, Smith TB, Cortez-Retamozo V, Grigoryeva LS, Roy JW, Hill E, Pittet MJ, Breton S, Da Silva N
Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis.
Biol Reprod. 2014;90(5):90 - PMID: 24648397 - PMCID: PMC4076373
Golub MS, Hogrefe CE, Malka R, Higgins JM
Developmental Plasticity of red blood cell homeostasis.
Am J Hematol. 2014;89(5):459-66 - PMID: 24415575 - PMCID: PMC4086753
Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG
Hereditary xerocytosis revisited.
Am J Hematol. 2014;89(12):1142-1146 - PMID: 25044010 - PMCID: PMC4237618
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J
Chemical Interrogation of the Malaria Kinome.
Chembiochem. 2014;15(13):1920-30 - PMID: 25111632 - PMCID: PMC4237307 - Cover
Miranda KC, Bond DT, Levin JZ, Adiconis X, Sivachenko A, Russ C, Brown D, Nusbaum C, Russo LM
Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA.
PLoS ONE. 2014;9(5):e96094 - PMID: 24816817 - PMCID: PMC4015934
Elman JS, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B
Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells.
PLoS ONE. 2014;9(2):e89882 - PMID: 24587097 - PMCID: PMC3931832
Hsieh LC, Chen JW, Wang LY, Tsang YM, Shueng PW, Liao LJ, Lo WC, Lin YC, Tseng CF, Kuo YS, Jhuang JY, Tien HJ, Juan HF, Hsieh CH
Predicting the severity and prognosis of trismus after intensity-modulated radiation therapy for oral cancer patients by magnetic resonance imaging.
PLoS ONE. 2014;9(3):e92561 - PMID: 24658376 - PMCID: PMC3962418
Mehan WA, González RG, Buchbinder BR, Chen JW, Copen WA, Gupta R, Hirsch JA, Hunter GJ, Hunter S, Johnson JM, Kelly HR, Larvie M, Lev MH, Pomerantz SR, Rapalino O, Rincon S, Romero JM, Schaefer PW, Shah V
Optimal Brain MRI Protocol for New Neurological Complaint.
PLoS ONE. 2014;9(10):e110803 - PMID: 25343371 - PMCID: PMC4208779
Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D
High throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration.
Am J Physiol Cell Physiol. 2014;307(7):C597-605 - PMID: 24944200 - PMCID: PMC4187055
Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM
Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume.
Cytometry A. 2014;85(4):332-8 - PMID: 24677669 - PMCID: PMC4717472
Chow MJ, Turcotte R, Lin CP, Zhang Y
Arterial Extracellular Matrix: A Mechanobiological Study of the Contributions and Interactions of Elastin and Collagen.
Biophys J. 2014;106(12):2684-2692 - PMID: 24940786 - PMCID: PMC4070071
Hedgire SS, Mino-Kenudson M, Elmi A, Thayer S, Fernandez-Del Castillo C, Harisinghani MG
Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation.
Int J Nanomedicine. 2014;9:1891-1896 - PMID: 24790431 - PMCID: PMC4000182
Kim KM, Cambria RP, Isselbacher EM, Baker JN, LaMuraglia GM, Stone JR, MacGillivray TE
Contemporary Surgical Approaches and Outcomes in Adults With Kommerell Diverticulum.
Ann Thorac Surg. 2014;98(4):1347-1354 - PMID: 25134861
Alt C, Runnels JM, Mortensen LJ, Zaher W, Lin C
In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment.
Invest Ophthalmol Vis Sci. 2014;55(8):5314-5319 - PMID: 25082884
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.
J Crohns Colitis. 2014;8(9):956-63 - PMID: 24559536 - PMCID: PMC4136996
Dubach JM, Vinegoni C, Weissleder R
Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging.
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Smith TB, Cortez-Retamozo V, Grigoryeva LS, Hill E, Pittet MJ, Da Silva N
Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis.
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Turcotte R, Alt C, Mortensen LJ, Lin CP
Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy.
Biomed Opt Express. 2014;5(10):3578-88 - PMID: 25360374 - PMCID: PMC4206326
Mortensen LJ, Alt C, Turcotte R, Masek M, Liu TM, Côté DC, Xu C, Intini G, Lin CP
Femtosecond laser bone ablation with a high repetition rate fiber laser source.
Biomed Opt Express. 2014;6(1):32-42 - PMID: 25657872 - PMCID: PMC4317121
Pulli B, Chen JW
Imaging Neuroinflammation - from Bench to Bedside.
J Clin Cell Immunol. 2014;5:ePub - PMID: 25525560 - PMCID: PMC4266918
Wu JW, Runnels JM, Lin CP
Intravital imaging of hematopoietic stem cells in the mouse skull.
Methods Mol Biol. 2014;1185:247-65 - PMID: 25062634
Keliher EJ, Klubnick JA Reiner T, Mazitschek R, Weissleder R
Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes.
ChemMedChem. 2014;9(7):1368-73 - PMID: 24596307 - PMCID: PMC4145401
Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R
Platinum Compounds for High-Resolution In Vivo Cancer Imaging.
ChemMedChem. 2014;9(6):1131-5 - PMID: 24504646 - PMCID: PMC4037345
Lartey FM, Ahn GO, Ali R, Rosenblum S, Miao Z, Arksey N, Shen B, Colomer MV, Rafat M, Liu H, Alejandre-Alcazar MA, Chen JW, Palmer T, Chin FT, Guzman R, Loo BW, Graves E
The Relationship Between Serial [(18) F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice.
Mol Imaging Biol. 2014;16(6):821-9 - PMID: 24865401 - PMCID: PMC4237703
Panizzi P, Stone JR, Nahrendorf M
Endocarditis and molecular imaging.
J Nucl Cardiol. 2014;21(3):486-95 - PMID: 24797384 - PMCID: PMC4106242
Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA
Computational pathology: an emerging definition.
Arch Pathol Lab Med. 2014;138(9):1133-8 - PMID: 25171694
Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Mode of Childbirth and Long-Term Outcomes in Women with Inflammatory Bowel Diseases.
Dig Dis Sci. 2014;60(2):471-7 - PMID: 25213079 - PMCID: PMC4304947
Wollack JW, Monson BJ, Dozier JK, Dalluge JJ, Poss K, Hilderbrand SA, Distefano MD
Site-Specific Labeling of Proteins and Peptides with Trans-cyclooctene Containing Handles Capable of Tetrazine Ligation.
Chem Biol Drug Des. 2014;84(2):140-7 - PMID: 24899362 - PMCID: PMC4107141
Stone JR
Novel prognostic tissue markers in congestive heart failure.
Cardiovasc Pathol. 2014;24(2):65-70 - PMID: 25453729
Pauk M, Grgurevic L, Brkljacic J, Kufner V, Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt JL, Lin HY, Volarevic S, Vukicevic S
Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice.
Int Orthop. 2014;39(1):161-172 - PMID: 25300398
Zhao Y, Zhou P, Liu B, Bambakidis T, Mazitschek R, Alam HB, Li Y
Protective effect of suberoylanilide hydroxamic acid against lipopolysaccharide-induced liver damage in rodents.
J Surg Res. 2014;194(2):544-550 - PMID: 25479907 - PMCID: PMC4361238
Zhao T, Li Y, Liu B, Halaweish I, Mazitschek R, Alam HB
Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model.
J Surg Res. 2014;190(2):647-54 - PMID: 24613069 - PMCID: PMC4267528
Oklu R, Stone JR, Albadawi H, Watkins MT
Extracellular Traps in Lipid-Rich Lesions of Carotid Atherosclerotic Plaques: Implications for Lipoprotein Retention and Lesion Progression.
J Vasc Interv Radiol. 2014;25(4):631-4 - PMID: 24581730
Iyer VR, Hedgire SS, Hoskote SS, Borczuk D, Harisinghani MG
Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up.
Abdom Imaging. 2014;40(6):1481-6 - PMID: 25516214
Hedgire SS, Eberhardt SC, Borczuk R, McDermott S, Harisinghani MG
Interpretation and reporting multiparametric prostate MRI: a primer for residents and novices.
Abdom Imaging. 2014;39(5):1036-51 - PMID: 24566965
Winkler DA, Burden FR, Yan B, Weissleder R, Tassa C, Shaw S, Epa VC
Modelling and predicting the biological effects of nanomaterials.
SAR QSAR Environ Res. 2014;25(2):161-72 - PMID: 24625316
Higgins JM
Red Blood Cell Population Dynamics.
Clin Lab Med. 2014;35(1):43-57 - PMID: 25676371 - PMCID: Clin Lab Med
Sheth RA, Bittencourt LK, Guimaraes AR
Diffusion-Weighted Imaging of the Male Pelvis.
Magn Reson Imaging Clin N Am. 2014;22(2):145-163 - PMID: 24792675
Harisinghani MG
The male pelvis.
Magn Reson Imaging Clin N Am. 2014;22(2):xi - PMID: 24792681
Bell DL, Stapleton CJ, Terry AR, Stone JR, Ogilvy CS
Clinical presentation and treatment considerations of a ruptured posterior spinal artery pseudoaneurysm.
J Clin Neurosci. 2014;21(7):1273-6 - PMID: 24572933
Park D, Spencer JA, Lin CP, Scadden DT
Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair.
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Hedgire SS, Tabatabaei S, McDermott S, Feldman A, Dahl DM, Harisinghani MG
Diversion ahead: imaging appearance of urinary diversions and reservoirs.
Clin Imaging. 2014;38(4):418-427 - PMID: 24602415
Hedgire SS, Elmi A, Kambadakone AR, Yoon S, Blake M, Harisinghani MG
MDCT imaging of Alloderm biologic mesh spacers in the abdomen and pelvis - preliminary experience.
Clin Imaging. 2014;38(3):279-82 - PMID: 24556330
Swirski FK
Monocyte recruitment and macrophage proliferation in atherosclerosis.
Kardiol Pol. 2014;72(4):311-4 - PMID: 24526549
Wang CY, Meynard D, Lin HY
The role of TMPRSS6/matriptase-2 in iron regulation and anemia.
Front Pharmacol. 2014;5:114 - PMID: 24966834 - PMCID: PMC4053654
Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ
Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2.
Physiol Rep. 2014;2(12):ePub - PMID: 25472608 - PMCID: PMC4332208
Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS, Reiner T
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis.
ChemistryOpen. 2014;3(2):48-53 - PMID: 24808990 - PMCID: PMC4000166
Swirski FK
Inflammation and repair in the ischaemic myocardium.
Hamostaseologie. 2014;35(1):34-6 - PMID: 25375277
Mietto C, Pinciroli R, Piriyapatsom A, Thomas JG, Bry L, Delaney ML, Du Bois A, Truelove J, Ackman JB, Wojtkiewicz GR, Nahrendorf M, Kacmarek RM, Berra L
Tracheal Tube Obstruction in Mechanically Ventilated Patients Assessed by High-resolution Computed Tomography.
Anesthesiology. 2014;121(6):1226-1235 - PMID: 25254903
Alieva M, Ritsma L, Giedt RJ, Weissleder R, van Rheenen J
Imaging windows for long-term intravital imaging: general overview
Intravital. 2014;3:2: e29917
Core AB, Canali S, Babitt JL
Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis.
Front Pharmacol. 2014;5:104 - PMID: 24860505 - PMCID: PMC4026703
Ausiello D, Shaw S
Quantitative human phenotyping: the next frontier in medicine.
Trans Am Clin Climatol Assoc. 2014;125:219-28 - PMID: 25125736 - PMCID: PMC4112685
Baron JM, Dighe AS, Arnaout R, Balis UJ, Black-Schaffer WS, Carter AB, Henricks WH, Higgins JM, Jackson BR, Kim J, Klepeis VE, Le LP, Louis DN, Mandelker D, Mermel CH, Michaelson JS, Nagarajan R, Platt ME, Quinn AM, Rao L, Shirts BH, Gilbertson JR
The 2013 symposium on pathology data integration and clinical decision support and the current state of field.
J Pathol Inform. 2014;5:2 - PMID: 24672737 - PMCID: PMC3952400
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases.
Aliment Pharmacol Ther. 2014;39(10):1136-42 - PMID: 24641590 - PMCID: PMC4187206
Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy.
Nat Med. 2014;20(11):1301-9 - PMID: 25344738
Ali M, Pulli B, Chen JW
Molecular imaging of macrophage enzyme activity in cardiac inflammation.
Curr Cardiovasc Imaging Rep. 2014;7(4):9258 - PMID: 24729833 - PMCID: PMC3979571
Awad MM, Katayama R, McTigue M, Liu W, Deng YL, Brooun A, Friboulet L, Huang D, Falk MD, Timofeevski S, Wilner KD, Lockerman EL, Khan TM, Mahmood S, Gainor JF, Digumarthy SR, Stone JR, Mino-Kenudson M, Christensen JG, Iafrate AJ, Engelman JA, Shaw AT
Acquired Resistance to Crizotinib from a Mutation in CD74-ROS1.
New Engl J Med. 2013;368(25):2395-401 - PMID: 23724914 - PMCID: PMC3878821
Steele DJ, Kasmar AG, Guimaraes AR, Dekker JP
Case records of the Massachusetts General Hospital. Case 3-2013. A 72-year-old woman with abdominal pain and distention after peritoneal dialysis.
New Engl J Med. 2013;368(4):375-85 - PMID: 23343067
Simmons LH, Guimaraes AR, Zukerberg LR
Case 6-2013.
New Engl J Med. 2013;368(8):757-65 - PMID: 23425169
Olumi AF, Kaufman DS, Zietman A, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 25-2013. A 71-year-old man with hematuria and a mass in the bladder.
New Engl J Med. 2013;369(7):660-7 - PMID: 23944304
Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A
Charting a dynamic DNA methylation landscape of the human genome.
Nature. 2013;500(7463):477-81 - PMID: 23925113 - PMCID: PMC3821869
Tata PR, Mou H, Pardo-Saganta A, Zhao R, Prabhu M, Law BM, Vinarsky V, Cho JL, Breton S, Sahay A, Medoff BD, Rajagopal J
Dedifferentiation of committed epithelial cells into stem cells in vivo.
Nature. 2013;503(7475):218-23 - PMID: 24196716 - PMCID: PMC4035230
Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.
Nat Biotechnol. 2013;31(12):1137-42 - PMID: 24108092 - PMCID: PMC3858462
Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.
Nat Biotechnol. 2013;31(10):898-907 - PMID: 24013197 - PMCID: PMC4058317
Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, Bernstein BE
Locus-specific editing of histone modifications at endogenous enhancers.
Nat Biotechnol. 2013;31(12):1133-6 - PMID: 24013198 - PMCID: PMC3858395
Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE
Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues.
Cell. 2013;152(3):642-54 - PMID: 23333102 - PMCID: PMC3563935
Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A
Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells.
Cell. 2013;153(5):1149-1163 - PMID: 23664763 - PMCID: PMC3709577
Chung HJ, Castro CM, Im H, Lee H*, Weissleder R*
A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria
Nat Nanotechnol. 2013;8(5):369-75 - PMID: 23644570 - PMCID: PMC3711657
Swirski FK, Nahrendorf M
Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure.
Science. 2013;339(6116):161-6 - PMID: 23307733 - PMCID: PMC3891792
Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide.
Science. 2013;342(6161):971-6 - PMID: 24264990 - PMCID: PMC4048947
Suvà ML, Riggi N, Bernstein BE
Epigenetic reprogramming in cancer.
Science. 2013;339(6127):1567-70 - PMID: 23539597 - PMCID: PMC3821556
Garris C, Pittet MJ
Therapeutically reeducating macrophages to treat GBM.
Nature Med. 2013;19(10):1207-1208 - PMID: 24100977
Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT
Differential regulation of myeloid leukemias by the bone marrow microenvironment.
Nature Med. 2013;19(11):1513-7 - PMID: 24162813 - PMCID: PMC3827980
Robbins CS, Hilgendorf I, Weber GF, Theurl I, Iwamoto Y, Figueiredo JL, Gorbatov R, Sukhova GK, Gerhardt LM, Smyth D, Zavitz CC, Shikatani EA, Parsons M, Rooijen NV, Lin HY, Husain M, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
Nature Med. 2013;19(9):1166-72 - PMID: 23933982 - PMCID: PMC3769444
Silberstein LE, Lin CP
A new image of the hematopoietic stem cell vascular niche.
Cell Stem Cell. 2013;13(5):514-6 - PMID: 24209758 - PMCID: PMC4148778
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.
Cancer Cell. 2013;24(1):45-58 - PMID: 23770013 - PMCID: PMC3746037
Bronte V, Pittet MJ
The spleen in local and systemic regulation of immunity.
Immunity. 2013;39(5):806-18 - PMID: 24238338 - PMCID: PMC3912742
Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ
Angiotensin II Drives the Production of Tumor-Promoting Macrophages
Immunity. 2013;38(2):296-308 - PMID: 23333075 - PMCID: PMC3582771
Chapman S, Dobrovolskaia M, Farahani K, Goodwin A, Joshi A, Lee H, Meade T, Pomper M, Ptak K, Rao J, Singh R, Sridhar S, Stern S, Wang A, Weaver JB, Woloschak G, Yang L
Nanoparticles for cancer imaging: The good, the bad, and the promise.
Nano Today. 2013;8(5):454-460 - PMID: 25419228 - PMCID: PMC4240321
Kumar V, Patel N, Van Houzen N, Saini N
Brugada-type electrocardiographic changes induced by Fever.
Circulation. 2013;127(21):2145-6 - PMID: 23716383
Majmudar MD, Keliher EJ, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, Dickneite G, Chen JW, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M
Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice.
Circulation. 2013;127(20):2038-2046 - PMID: 23616627 - PMCID: PMC3661714
van der Laan AM, Ter Horst EN, Delewi R, Begieneman MP, Krijnen PA, Hirsch A, Lavaei M, Nahrendorf M, Horrevoets AJ, Niessen HW, Piek JJ
Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir.
Eur Heart J. 2013;35(6):376-85 - PMID: 23966310 - PMCID: PMC3916776
Im H, Bantz KC, Lee SH, Johnson TW, Haynes CL, Oh SH
Self-assembled plasmonic nanoring cavity arrays for SERS and LSPR biosensing.
Adv Mater. 2013;25(19):2678-85 - PMID: 23436239
Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.
J Exp Med. 2013;210(12):2641-59 - PMID: 24218140 - PMCID: PMC3832937
Swirski FK, Nahrendorf M
Macrophage - stem cell crosstalk after myocardial infarction.
J Am Coll Cardiol. 2013;62(20):1902-4 - PMID: 23973700
Courties G, Heidt T, Sebas M, Iwamoto Y, Jeon D, Truelove J, Tricot B, Wojtkiewicz G, Dutta P, Sager HB, Borodovsky A, Novobrantseva T, Klebanov B, Fitzgerald K, Anderson DG, Libby P, Swirski FK, Weissleder R, Nahrendorf M
In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.
J Am Coll Cardiol. 2013;63(15):1556-66 - PMID: 24361318 - PMCID: PMC3992176
Yang* KS, Budin* G, Tassa C, Kister O, Weissleder R
Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells
Angew Chem Int Ed Engl. 2013;52(40):10593-7 - PMID: 23960025 - PMCID: PMC3856564
Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R
BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes.
Angew Chem Int Ed Engl. 2013;52(27):6917-6920 - PMID: 23712730 - PMCID: PMC3875324
Isono K, Endo TA, Ku M, Yamada D, Suzuki R, Sharif J, Ishikura T, Toyoda T, Bernstein BE, Koseki H
SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing.
Dev Cell. 2013;26(6):565-577 - PMID: 24091011
Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ
Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.
Gastroenterology. 2013;145(6):1347-57 - PMID: 23973919 - PMCID: PMC3840157
Rho J, Chung J, Im H, Liong M, Shao H, Castro CM, Weissleder R, Lee H
Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles.
ACS Nano. 2013;7(12):11227-33 - PMID: 24295203 - PMCID: PMC3898036
Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, Charollais A, Ramadori P, Foti M, Meda P, Féraille E, Brown D, Hasler U
Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters.
Autophagy. 2013;9(4):550-67 - PMID: 23380587 - PMCID: PMC3627670
Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH
Endoscopic Time-Lapse Imaging of Immune Cells in Infarcted Mouse Hearts.
Circ Res. 2013;112(6):891-899 - PMID: 23392842 - PMCID: PMC3834270
Swirski FK, Robbins CS
Neutrophils usher monocytes into sites of inflammation.
Circ Res. 2013;112(5):744-5 - PMID: 23449542
Nahrendorf M, Swirski FK
Monocyte and macrophage heterogeneity in the heart.
Circ Res. 2013;112(12):1624-33 - PMID: 23743228 - PMCID: PMC3753681
Majmudar MD, Yoo J, Keliher E, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson D, Swirski FK, Weissleder R, Nahrendorf M
Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques.
Circ Res. 2013;112(5):755-61 - PMID: 23300273 - PMCID: PMC3586287 - Cover
Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ, Richardson PG, Hideshima T, Anderson KC
Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma.
Leukemia. 2013;28(3):680-9 - PMID: 23913134 - PMCID: PMC4165599
Hideshima T, Mazitschek R, Santo L, Mimura N, Gorgun G, Richardson PG, Raje N, Anderson KC
Induction of differential apoptotic pathways in multiple myeloma cells by class selective histone deacetylase inhibitors.
Leukemia. 2013;28(2):457-60 - PMID: 24150220 - PMCID: PMC4405100
Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW
Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.
Nat Commun. 2013;4:2189 - PMID: 23877263 - PMCID: PMC3740589
Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H*, Weissleder R*
Magnetic barcode assay for genetic detection of pathogens
Nat Commun. 2013;4:1752 - PMID: 23612293 - PMCID: PMC3635151
Ageta-Ishihara N, Miyata T, Ohshima C, Watanabe M, Sato Y, Hamamura Y, Higashiyama T, Mazitschek R, Bito H, Kinoshita M
Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.
Nat Commun. 2013;4:2532 - PMID: 24113571 - PMCID: PMC3826633
Chen X, Park HR, Pelton M, Piao X, Lindquist NC, Im H, Kim YJ, Ahn JS, Ahn KJ, Park N, Kim DS, Oh SH
Atomic layer lithography of wafer-scale nanogap arrays for extreme confinement of electromagnetic waves.
Nat Commun. 2013;4:2361 - PMID: 23999053
Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R
Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.
Nat Commun. 2013;4:1504 - PMID: 23422672 - PMCID: PMC3579506
Liu Y, Shoji-Kawata S, Sumpter RM, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.
Proc Natl Acad Sci U S A. 2013;110(51):20364-71 - PMID: 24277826 - PMCID: PMC3870705
Miller MA, Meyer AS, Beste MT, Lasisi Z, Reddy S, Jeng KW, Chen CH, Han J, Isaacson K, Griffith LG, Lauffenburger DA
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling.
Proc Natl Acad Sci U S A. 2013;110(22):E2074-83 - PMID: 23674691 - PMCID: PMC3670354
Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.
Proc Natl Acad Sci U S A. 2013;110(24):9776-81 - PMID: 23720309 - PMCID: PMC3683718
Peterson VM*, Castro CM*, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R
Ascites analysis by a microfluidic chip allows tumor-cell profiling
Proc Natl Acad Sci U S A. 2013;110(51):E4978-86 - PMID: 24297935 - PMCID: PMC3870756
Squadrito ML, Etzrodt M, De Palma M, Pittet MJ
MicroRNA-mediated control of macrophages and its implications for cancer.
Trends Immunol. 2013;34(7):350-9 - PMID: 23498847 - PMCID: PMC3700601
Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM
Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.
Ann Rheum Dis. 2013;73(6):1170-1175 - PMID: 23716066 - PMCID: PMC3815491
Levy O, Zhao W, Mortensen LJ, Leblanc S, Tsang K, Fu M, Phillips JA, Sagar V, Anandakumaran P, Ngai J, Cui CH, Eimon P, Angel M, Lin CP, Yanik MF, Karp JM
mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation.
Blood. 2013;122(14):e23-e32 - PMID: 23980067 - PMCID: PMC3790516
Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ
Circulating CD34+ progenitor cell frequency is associated with clinical and genetic factors.
Blood. 2013;121(8):e50-6 - PMID: 23287867 - PMCID: PMC3578962
Meynard D, Babitt JL, Lin HY
The liver: conductor of systemic iron regulation.
Blood. 2013;123(2):168-76 - PMID: 24200681 - PMCID: PMC3888285
Brown D, Jenny Lu HA
Aquaporin-2 Inhibitors: Fishing in the Chemical Pool.
J Am Soc Nephrol. 2013;24(5):685-6 - PMID: 23599384
Wildgruber M, Swirski FK, Zernecke A
Molecular Imaging of Inflammation in Atherosclerosis.
Theranostics. 2013;3(11):865-884 - PMID: 24312156 - PMCID: PMC3841337
Shan G, Weissleder R, Hilderbrand SA
Upconverting Organic Dye Doped Core-Shell Nano-Composites for Dual-Modality NIR Imaging and Photo-Thermal Therapy.
Theranostics. 2013;3(4):267-74 - PMID: 23606913 - PMCID: PMC3630527
Jochems J, Boulden J, Lee BG, Blendy JA, Jarpe M, Mazitschek R, Van Duzer JH, Berton O
Antidepressant-Like Properties of Novel HDAC6 Selective Inhibitors with Improved Brain Bioavailability.
Neuropsychopharmacology. 2013;39(2):389-400 - PMID: 23954848 - PMCID: PMC3870780
Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari KI, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J
Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1.
Cancer Res. 2013;74(3):738-50 - PMID: 24310399 - PMCID: PMC3928601
Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK
In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.
Nucleic Acids Res. 2013;41(19):e181 - PMID: 23945932 - PMCID: PMC3799455
Huang J, McKee M, Huang HD, Xiang A, Davidson AJ, Lu HA
A zebrafish model of conditional targeted podocyte ablation and regeneration.
Kidney Int. 2013;83(6):1193-200 - PMID: 23466998 - PMCID: PMC3672345
Pucci F, Pittet MJ
Molecular Pathways: Tumor-derived microvesicles and their interactions with immune cells in vivo.
Clin Cancer Res. 2013;19(10):2598-604 - PMID: 23426276 - PMCID: PMC3655093
Liu R, Rallo R, Weissleder R, Tassa C, Shaw S, Cohen Y
Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries.
Small. 2013;9(9-10):1842-52 - PMID: 23423856
Im H, Oh SH
Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges.
Small. 2013;10(4):680-4 - PMID: 24123889
Im H, Oh SH
Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges.
Small. 2013;10(4):680-4 - PMID: 24123889
Meyer AS, Miller MA, Gertler FB, Lauffenburger DA
The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells.
Sci Signal. 2013;6(287):ra66 - PMID: 23921085 - PMCID: PMC3947921
Courties G, Moskowitz MA, Nahrendorf M
The Innate Immune System After Ischemic Injury: Lessons to Be Learned From the Heart and Brain.
JAMA Neurol. 2013;71(2):233-6 - PMID: 24296962 - PMCID: PMC3946050
Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE
An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma.
Cell Rep. 2013;3(5):1567-1579 - PMID: 23707066 - PMCID: PMC3774301
Breton S, Brown D
Regulation of Luminal Acidification by the V-ATPase.
Physiology (Bethesda). 2013;28(5):318-29 - PMID: 23997191 - PMCID: PMC3768094
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP
Association Between Reduced Plasma 25-hydroxy Vitamin D and Increased Risk of Cancer in Patients with Inflammatory Bowel Diseases.
Clin Gastroenterol Hepatol. 2013;12(5):821-7 - PMID: 24161349 - PMCID: PMC3995841
Agasti SS, Laughney AM, Kohler RH, Weissleder R
A photoactivatable drug–caged fluorophore conjugate allows direct quantification of intracellular drug transport
Chem Commun. 2013;49(94):11050-2 - PMID: 24135896 - PMCID: PMC3856557
Kumar V, Donahue DM, Patel N
An unexpected complication during cardiac catheterization: blood clot cast of the tracheobronchial tree: first case during cardiac catheterization.
JACC Cardiovasc Interv. 2013;6(4):e19 - PMID: 23597616
Turan S, Fernandez-Rebollo E, Aydin C, Zoto T, Reyes M, Bounoutas G, Chen M, Weinstein LS, Erben RG, Marshansky V, Bastepe M
Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone-resistance due to heterozygous Gαs disruption.
J Bone Miner Res. 2013;29(3):749-60 - PMID: 23956044 - PMCID: PMC3926912
Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H
Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells.
Lab Chip. 2013;14(1):14-23 - PMID: 23835814 - PMCID: PMC3844052
Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX
Stress-induced hematopoietic failure in the absence of immediate early response gene X-1.
Haematologica. 2013;99(2):282-91 - PMID: 24056813 - PMCID: PMC3912958
Issadore D*, Chung HJ*, Chung J, Budin G, Weissleder R*, Lee H*
μHall Chip for Sensitive Detection of Bacteria
Adv Healthc Mater. 2013;2(9):1224-8 - PMID: 23495188 - PMCID: PMC4340655
Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE
Fluorescence Tomography of Rapamycin-Induced Autophagy and Cardioprotection In Vivo.
Circ Cardiovasc Imaging. 2013;6(3):441-7 - PMID: 23537953 - PMCID: PMC3805276
Ueno T, Dutta P, Keliher E, Leuschner F, Majmudar M, Marinelli B, Iwamoto Y, Figueiredo JL, Christen T, Swirski FK, Libby P, Weissleder R, Nahrendorf M
Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts.
Circ Cardiovasc Imaging. 2013;6(4):568-73 - PMID: 23771986 - PMCID: PMC3734553
Zeglis BM, Sevak KK, Reiner T, Mohindra P, Carlin SD, Zanzonico P, Weissleder R, Lewis JS
A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry.
J Nucl Med. 2013;54(8):1389-96 - PMID: 23708196 - PMCID: PMC4151562
Frantz S, Hofmann U, Fraccarollo D, Schäfer A, Kranepuhl S, Hagedorn I, Nieswandt B, Nahrendorf M, Wagner H, Bayer B, Pachel C, Schön MP, Kneitz S, Bobinger T, Weidemann F, Ertl G, Bauersachs J
Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction.
FASEB J. 2013;27(3):871-81 - PMID: 23159933
Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R
Targeting cathepsin e in pancreatic cancer by a small molecule allows in vivo detection.
Neoplasia. 2013;15(7):684-93 - PMID: 23814481 - PMCID: PMC3689232 - Cover
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ
Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules.
ACS Chem Biol. 2013;8(12):2724-33 - PMID: 24168452 - PMCID: PMC3951132
Libby P, Nahrendorf M, Swirski FK
Monocyte heterogeneity in cardiovascular disease.
Semin Immunopathol. 2013;35(5):553-62 - PMID: 23839097 - PMCID: PMC3755757
McCarthy JR
Book review: the handbook of nanomedicine (2nd edition).
Nanomedicine (Lond). 2013;8(2):173-5 - PMID: 23394153
Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM
Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and miniaturized micro-NMR system.
Nanomedicine (Lond). 2013;9(7):1009-17 - PMID: 23570873 - PMCID: PMC4330975
Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP
Normalization of Plasma 25-Hydroxy Vitamin D Is Associated with Reduced Risk of Surgery in Crohn's Disease.
Inflamm Bowel Dis. 2013;19(9):1921-1927 - PMID: 23751398 - PMCID: PMC3720838
Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA
Fluorescence Endoscopy of Cathepsin Activity Discriminates Dysplasia from Colitis.
Inflamm Bowel Dis. 2013;19(7):1339-1345 - PMID: 23591598 - PMCID: PMC4306589
Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D,
Defining Kidney Biology to Understand Renal Disease.
Clin J Am Soc Nephrol. 2013;9(4):809-11 - PMID: 24370769 - PMCID: PMC3974369
Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD, Hallows KR, Brown D, Bouley R, Vilardaga JP
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.
J Biol Chem. 2013;288(39):27849-60 - PMID: 23935101 - PMCID: PMC3784700
Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Gruber G, Marshansky V
The N-terminus of a-Subunit Isoforms is Involved in Signaling between V-ATPase and Cytohesin-2.
J Biol Chem. 2013;288(8):5896-913 - PMID: 23288846 - PMCID: PMC3581410
Clardy SM, Keliher EJ, Mohan JF, Sebas M, Benoist C, Mathis D, Weissleder R
Fluorescent Exendin-4 Derivatives for Pancreatic β-Cell Analysis.
Bioconjug Chem. 2013;25(1):171-177 - PMID: 24328216 - PMCID: PMC4016126
Yuan Y, Andronesi OC, Bortfeld TR, Richter C, Wolf R, Guimaraes AR, Hong TS, Seco J
Feasibility study of in vivo MRI based dosimetric verification of proton end-of-range for liver cancer patients.
Radiother Oncol. 2013;106(3):378-82 - PMID: 23473960
Paly JJ, Efstathiou JA, Hedgire SS, Chung PW, O'Malley M, Shah A, Bekelman JE, Harisinghani M, Shipley WU, Zietman AL, Beard C
Mapping patterns of nodal metastases in seminoma: Rethinking radiotherapy fields.
Radiother Oncol. 2013;106(1):64-8 - PMID: 23321493 - Cover
Bhatia RS, Kumar V, Picard MH, Weiner RB
Comparison of the 2008 and 2011 appropriate use criteria for stress echocardiography.
J Am Soc Echocardiogr. 2013;26(4):339-43 - PMID: 23313389
Faris JE, Blaszkowsky LS, McDermott S, Guimaraes AR, Szymonifka J, Huynh MA, Ferrone CR, Wargo JA, Allen JN, Dias LE, Kwak EL, Lillemoe KD, Thayer SP, Murphy JE, Zhu AX, Sahani DV, Wo JY, Clark JW, Fernandez-Del Castillo C, Ryan DP, Hong TS
FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience.
Oncologist. 2013;18(5):543-548 - PMID: 23657686 - PMCID: PMC3662845
Lameijer MA, Tang J, Nahrendorf M, Beelen RH, Mulder WJ
Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease.
Expert Rev Mol Diagn. 2013;13(6):567-80 - PMID: 23895127 - PMCID: PMC4110962
Swirski FK, Nahrendorf M
Imaging macrophage development and fate in atherosclerosis and myocardial infarction.
Immunol Cell Biol. 2013;91(4):297-303 - PMID: 23207281 - PMCID: PMC3875224
Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW
Lipid and lipoprotein levels and trends in rheumatoid arthritis compared to the general population.
Arthritis Care Res (Hoboken). 2013;65(12):2046-50 - PMID: 23925980 - PMCID: PMC4060244
Giedt RJ, Koch PD, Weissleder R
Single Cell Analysis of Drug Distribution by Intravital Imaging.
PLoS ONE. 2013;8(4):e60988 - PMID: 23593370 - PMCID: PMC3622689
Prabhakar S, Goto J, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO
Stochastic model of tsc1 lesions in mouse brain.
PLoS ONE. 2013;8(5):e64224 - PMID: 23696872 - PMCID: PMC3655945
Kim E, Yang K, Weissleder R
Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET
PLoS ONE. 2013;8 (11):e81275 - PMID: 24265843 - PMCID: PMC3827223
Meynard D, Sun CC, Wu Q, Chen W, Chen S, Nelson CN, Waters MJ, Babitt JL, Lin HY
Inflammation Regulates TMPRSS6 Expression via STAT5.
PLoS ONE. 2013;8(12):e82127 - PMID: 24376517 - PMCID: PMC3871639
Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL
Modeling disease severity in multiple sclerosis using electronic health records.
PLoS ONE. 2013;8(11):e78927 - PMID: 24244385 - PMCID: PMC3823928
Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, Wojtkiewicz G, Linnoila JJ, Chen JW
Measuring myeloperoxidase activity in biological samples.
PLoS ONE. 2013;8(7):e67976 - PMID: 23861842 - PMCID: PMC3702519
Carlson AL, Fujisaki J, Wu J, Runnels JM, Turcotte R, Spencer JA, Celso CL, Scadden DT, Strom TB, Lin CP
Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.
PLoS ONE. 2013;8(8):e69257 - PMID: 23990881 - PMCID: PMC3753322
Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR
Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells.
PLoS ONE. 2013;8(7):e67590 - PMID: 23844039 - PMCID: PMC3699654
Rice WL, Van Hoek AN, Păunescu TG, Huynh C, Goetze B, Singh B, Scipioni L, Stern LA, Brown D
High resolution helium ion scanning microscopy of the rat kidney.
PLoS ONE. 2013;8(3):e57051 - PMID: 23505418 - PMCID: PMC3591388
Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerté M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR
Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma.
PLoS ONE. 2013;8(3):e60156 - PMID: 23527308 - PMCID: PMC3603933
Mortensen LJ, Levy O, Phillips JP, Stratton T, Triana B, Ruiz JP, Gu F, Karp JM, Lin CP
Quantification of Mesenchymal Stem Cell (MSC) Delivery to a Target Site Using In Vivo Confocal Microscopy.
PLoS ONE. 2013;8(10):e78145 - PMID: 24205131 - PMCID: PMC3812161
Roy JW, Hill E, Ruan YC, Vedovelli L, Paunescu T, Brown D, Breton S
Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis.
Am J Physiol Cell Physiol. 2013;305(4):C436-46 - PMID: 23761626 - PMCID: PMC3891217
Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS
Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors.
Atherosclerosis. 2013;229(1):228-233 - PMID: 23701996 - PMCID: PMC3984590
Paunescu TG, Lu HA, Russo LM, Pastor-Soler NM, McKee M, McLaughlin MM, Bartlett BE, Breton S, Brown D
Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells.
Am J Physiol Renal Physiol. 2013;305(12):F1783-F1795 - PMID: 24133120 - PMCID: PMC3882446
Shum W, Hill E, Brown D, Breton S
Plasticity of basal cells during postnatal development in the rat epididymis.
Reproduction. 2013;146(5):455-469 - PMID: 23960170 - PMCID: PMC4106237
Sun CC, Vaja V, Chen S, Theurl I, Stepanek A, Brown DE, Cappellini MD, Weiss G, Hong CC, Lin HY, Babitt JL
A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats.
Nephrol Dial Transplant. 2013;28(7):1733-1743 - PMID: 23345622 - PMCID: PMC3707526
Zumbrennen-Bullough K, Babitt JL
The iron cycle in CKD: from genetics and experimental models to CKD patients.
Nephrol Dial Transplant. 2013;29(2):263-73 - PMID: 24235084 - PMCID: PMC3910345
Chung J*, Issadore D*, Ullal A*, Lee K, Weissleder R*, Lee H*
Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip
Biomicrofluidics. 2013;7(5):54107 - PMID: 24404070 - PMCID: PMC3790798
Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R
Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging.
Biomed Opt Express. 2013;4(10):2095-106 - PMID: 24156067 - PMCID: PMC3799669
Preston MA, Harisinghani MG, Mucci L, Witiuk K, Breau RH
Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancer.
BJU Int. 2013;111(3):514-7 - PMID: 23320634
McDermott S, Thayer SP, Fernandez-Del Castillo C, Mino-Kenudson M, Weissleder R, Harisinghani MG
Accurate prediction of nodal status in preoperative patients with pancreatic ductal adenocarcinoma using next-gen nanoparticle.
Transl Oncol. 2013;6(6):670-5 - PMID: 24466369 - PMCID: PMC3890701
Gunn AJ, Seethamraju RT, Hedgire S, Elmi A, Daniels GH, Harisinghani MG
Imaging Behavior of the Normal Adrenal on Ferumoxytol-Enhanced MRI: Preliminary Findings.
AJR Am J Roentgenol. 2013;201(1):117-21 - PMID: 23789664
Dhyani M, Anupindi SA, Ayyala R, Hahn PF, Gee MS
Defining an imaging algorithm for noncystic splenic lesions identified in young patients.
AJR Am J Roentgenol. 2013;201(6):W893-9 - PMID: 24261396
Hedgire SS, McDermott S, Borczuk D, Elmi A, Saini S, Harisinghani MG
The Spectrum of IgG4-Related Disease in the Abdomen and Pelvis.
AJR Am J Roentgenol. 2013;201(1):14-22 - PMID: 23789654
Rajesh A, Cloud G, Harisinghani MG
Improving the quality of manuscript reviews: impact of introducing a structured electronic template to submit reviews.
AJR Am J Roentgenol. 2013;200(1):20-3 - PMID: 23255737
Pestana N, Mortensen LJ, Runnels JP, Vickers D, Murthy SK, Lin CP, Niedre M
Improved diffuse fluorescence flow cytometer prototype for high sensitivity detection of rare circulating cells in vivo.
J Biomed Opt. 2013;18(7):77002 - PMID: 23831714 - PMCID: PMC3702234
Lartey FM, Ahn GO, Shen B, Cord KT, Smith T, Chua JY, Rosenblum S, Liu H, James ML, Chernikova S, Lee SW, Pisani LJ, Tirouvanziam R, Chen JW, Palmer TD, Chin FT, Guzman R, Graves EE, Loo BW
PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [(18)F]PBR06.
Mol Imaging Biol. 2013;16(1):109-17 - PMID: 23836504 - PMCID: PMC4141125
Wang H, Albadawi H, Siddiquee Z, Stone JM, Panchenko MP, Watkins MT, Stone JR
Altered vascular activation due to deficiency of the NADPH oxidase component p22(phox.)
Cardiovasc Pathol. 2013;23(1):35-42 - PMID: 24035466
Mitchell DG, Javitt MC, Glanc P, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Horowitz NS, Pandharipande PV, Pannu HK, Podrasky AE, Royal HD, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM
ACR Appropriateness Criteria Staging and Follow-up of Ovarian Cancer.
J Am Coll Radiol. 2013;10(11):822-7 - PMID: 24183551
Quencer KB, Nimkin K, Mino-Kenudson M, Gee MS
Detecting active inflammation and fibrosis in pediatric Crohn's disease: prospective evaluation of MR-E and CT-E.
Abdom Imaging. 2013;38(4):705-13 - PMID: 23361877 - PMCID: PMC4390174
Weber GF, Swirski FK
Immunopathogenesis of abdominal sepsis.
Langenbecks Arch Surg. 2013;399(1):1-9 - PMID: 24121723
van der Laan AM, Nahrendorf M, Piek JJ
Republished: Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response.
Postgrad Med J. 2013;89(1047):52-8 - PMID: 23257717
Oklu R, Deipolyi AR, Wicky S, Ergul E, Deik AA, Chen JW, Hirsch JA, Wojtkiewicz GR, Clish CB
Identification of small compound biomarkers of pituitary adenoma: a bilateral inferior petrosal sinus sampling study.
J Neurointerv Surg. 2013;6(7):541-6 - PMID: 24005126
González RG, Copen WA, Schaefer PW, Lev MH, Pomerantz SR, Rapalino O, Chen JW, Hunter GJ, Romero JM, Buchbinder BR, Larvie M, Hirsch JA, Gupta R
The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach.
J Neurointerv Surg. 2013;5 Suppl 1:i7-i12 - PMID: 23493340 - PMCID: PMC3623036
Podrasky AE, Javitt MC, Glanc P, Dubinsky T, Harisinghani MG, Harris RD, Khati NJ, Mitchell DG, Pandharipande PV, Pannu HK, Shipp TD, Siegel CL, Simpson L, Wall DJ, Wong-You-Cheong JJ, Zelop CM
ACR Appropriateness Criteria® Second and Third Trimester Bleeding.
Ultrasound Q. 2013;29(4):293-301 - PMID: 24263752
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY
Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications.
J Vis Exp. 2013;(79):e50772 - PMID: 24084440 - PMCID: PMC3924759
Mackay DD, Huesmann GR, Wu RI, Stone JR, Pless ML
Giant Cell Arteritis Causing Symmetric Bilateral Posterior Circulation Infarcts.
J Clin Rheumatol. 2013;19(7):393-6 - PMID: 24048110
Hedgire SS, Sainani NI, McDermott S, Hahn PF, Harisinghani MG
Mono-belly and beyond: spectrum of imaging manifestations of EBV infection in the abdomen.
Clin Imaging. 2013;37(4):711-7 - PMID: 23317894
Yoon TJ, Shao H, Weissleder R, Lee H
Oxidation Kinetics and Magnetic Properties of Elemental Iron Nanoparticles
Part. Part. Syst. Charact. 2013;30:667–671 - PMID: 24077230 - PMCID: PMC3783348
Coffey SE, Giedt RJ, Weissleder R
Automated analysis of clonal cancer cells by intravital imaging.
Intravital. 2013;2(3):ePub - PMID: 24349895 - PMCID: PMC3859690
Schietinger A, Arina A, Liu RB, Wells S, Huang J, Engels B, Bindokas V, Bartkowiak T, Lee D, Herrmann A, Piston DW, Pittet MJ, Lin PC, Zal T, Schreiber H
Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer.
OncoImmunology. 2013;2(11):e26677 - PMID: 24482750 - PMCID: PMC3895414
Cortez-Retamozo V, Engblom C, Pittet MJ
Remote control of macrophage production by cancer.
OncoImmunology. 2013;2(5):e24183 - PMID: 23762799 - PMCID: PMC3667905
Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerte' M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR
Soluble Guanylate Cyclase a1-Deficient Mice: a novel murine model for Primary Open Angle Glaucoma.
2013;20(2):65-6 - PMID: 25206015 - PMCID: PMC4117107
Bazari H, Guimaraes AR, Kushner YB
Case records of the Massachusetts General Hospital. Case 20-2012. A 77-year-old man with leg edema, hematuria, and acute renal failure.
New Engl J Med. 2012;366(26):2503-15 - PMID: 22738101
Kaufman DS, Zietman AL, McDougal WS, Dahl DM, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 9-2012. A 67-year-old man with a persistently elevated PSA level.
New Engl J Med. 2012;366(12):1143-50 - PMID: 22435374
Hunt DP, Becker AE, Guimaraes AR, Stemmer-Rachamimov A, Misdraji J
Case records of the Massachusetts General Hospital. Case 21-2012. A 27-year-old man with fatigue, weakness, weight loss, and decreased libido.
New Engl J Med. 2012;367(2):157-69 - PMID: 22784119
Zella GC, Gee MS, Badizadegan K
Case records of the Massachusetts General Hospital. Case 25-2012. A 15-year-old boy with abdominal pain, hematochezia, and anemia.
New Engl J Med. 2012;367(7):659-67 - PMID: 22894579
Stone JH, Patel VI, Oliveira GR, Stone JR
Case 38-2012.
New Engl J Med. 2012;367(24):2335-46 - PMID: 23234517
Dutta P*, Courties G*, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AN, Niessen HWM, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M
Myocardial infarction accelerates atherosclerosis
Nature. 2012;487(7407):325-9 - PMID: 22763456 - PMCID: PMC3401326
Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL
Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.
Nature. 2012;489(7414):155-9 - PMID: 22820254 - PMCID: PMC3991463
ENCODE Project Consortium, Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M
An integrated encyclopedia of DNA elements in the human genome.
Nature. 2012;489(7414):57-74 - PMID: 22955616 - PMCID: PMC3439153
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, Depinho RA
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism.
Cell. 2012;149(3):656-70 - PMID: 22541435 - PMCID: PMC3472002
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, Macdonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R
The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism.
Cell. 2012;151(6):1185-99 - PMID: 23217706 - PMCID: PMC3526953
Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H
DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.
Cell. 2012;149(7):1474-87 - PMID: 22726435
Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.
Nat Nanotechnol. 2012;7(6):389-93 - PMID: 22659608 - PMCID: PMC3898745
Ryan RJ, Bernstein BE
Molecular biology. Genetic events that shape the cancer epigenome.
Science. 2012;336(6088):1513-4 - PMID: 22723401
Rauch PJ*, Chudnovskiy A*, Robbins CS*, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK
Innate Response Activator B Cells Protect Against Microbial Sepsis
Science. 2012;335(6068):597-601 - PMID: 22245738 - PMCID: PMC3279743
Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, Erglis A, Lin FY, Dunning AM, Apruzzese P, Budoff MJ, Cole JH, Jaffer FA, Leon MB, Malpeso J, Mancini GB, Park SJ, Schwartz RS, Shaw LJ, Mauri L
Diagnostic Accuracy of Fractional Flow Reserve From Anatomic CT Angiography.
JAMA. 2012;:1-9 - PMID: 22922562 - PMCID: PMC4281479
Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R*, Lee H*
Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
Nature Med. 2012;18(12):1835-1840 - PMID: 23142818 - PMCID: PMC3518564
Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D
Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging.
Nat Immunol. 2012;13(4):361-8 - PMID: 22366893 - PMCID: PMC3309063 - Cover
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT
Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration.
Cell Stem Cell. 2012;10(3):259-72 - PMID: 22385654 - PMCID: PMC3652251
Abdel-Wahab O, Adli M, Lafave LM, Gao J, Hricik T, Shih AH, Pandey S, Patel JP, Chung YR, Koche R, Perna F, Zhao X, Taylor JE, Park CY, Carroll M, Melnick A, Nimer SD, Jaffe JD, Aifantis I, Bernstein BE, Levine RL
ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression.
Cancer Cell. 2012;22(2):180-93 - PMID: 22897849 - PMCID: PMC3422511
Rheinbay E, Louis DN, Bernstein BE, Suvà ML
A Tell-Tail Sign of Chromatin: Histone Mutations Drive Pediatric Glioblastoma.
Cancer Cell. 2012;21(3):329-331 - PMID: 22439930
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA
Programming human pluripotent stem cells into white and brown adipocytes.
Nat Cell Biol. 2012;14(2):209-19 - PMID: 22246346 - PMCID: PMC3385947
Swirski FK, Nahrendorf M, Libby P
The ins and outs of inflammatory cells in atheromata.
Cell Metab. 2012;15(2):135-6 - PMID: 22326216
Issadore D, Chung J*, Shao H*, Liong M, Ghazani AA, Castro CM, Weissleder R*, Lee H*
Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector
Sci Transl Med. 2012;4 (141):141ra92 - PMID: 22764208 - PMCID: PMC3603277 - Cover
Wood DK, Soriano A, Mahadevan L, Higgins JM, Bhatia SN
A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease.
Sci Transl Med. 2012;4(123):123ra26 - PMID: 22378926 - PMCID: PMC3633235 - Cover
Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, Meldrim J, Ram O, Cheng C, Gnirke A, Fisher S, Friedman N, Wong B, Bernstein BE, Nusbaum C, Hacohen N, Regev A, Amit I
A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals.
Mol Cell. 2012;47(5):810-22 - PMID: 22940246 - PMCID: PMC3873101
Moon H, Park HE, Kang J, Lee H, Cheong C, Lim YT, Ihm SH, Seung KB, Jaffer FA, Narula J, Chang K, Hong KS
Noninvasive Assessment of Myocardial Inflammation by Cardiovascular Magnetic Resonance in a Rat Model of Experimental Autoimmune Myocarditis.
Circulation. 2012;125(21):2603-12 - PMID: 22550157
Degousee N, Simpson J, Fazel S, Scholich K, Angoulvant D, Angioni C, Schmidt H, Korotkova M, Stefanski E, Wang XH, Lindsay TF, Ofek E, Pierre S, Butany J, Jakobsson PJ, Keating A, Li RK, Nahrendorf M, Geisslinger G, Backx PH, Rubin BB
Lack of Microsomal Prostaglandin E2 Synthase-1 in Bone Marrow Derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality after Acute Myocardial Infarction.
Circulation. 2012;125(23):2904-13 - PMID: 22589381
Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
Genome Res. 2012;22(9):1813-31 - PMID: 22955991 - PMCID: PMC3431496
Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis.
J Exp Med. 2012;209(1):123-37 - PMID: 22213805 - PMCID: PMC3260875
Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MPV, Niessen HWM, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, Tawakol A, Di Carli M, Weissleder R, Nahrendorf M
PET/MRI of Inflammation in Myocardial Infarction
J Am Coll Cardiol. 2012;59:153-163 - PMID: 22222080 - PMCID: PMC3257823
Budin G*, Chung HJ*, Lee H, Weissleder R
A Magnetic Gram Stain for Bacterial Detection.
Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380
Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R
Synthesis of [(18) F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging.
Angew Chem Int Ed Engl. 2012;51(19):4603-6 - PMID: 22473535 - PMCID: PMC3343182
Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R
Bioorthogonal Imaging of Aurora Kinase A in Live Cells.
Angew Chem Int Ed Engl. 2012;51(27):6598-603 - PMID: 22644700 - PMCID: PMC3523717
Xu C, Miranda-Nieves D, Ankrum JA, Matthiesen ME, Phillips J, Roes I, Wojtkiewicz GR, Juneja V, Kultima JR, Zhao W, Vemula PK, Lin CP, Nahrendorf M, Karp JM
Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles.
Nano Lett. 2012;12(8):4131-9 - PMID: 22769232 - PMCID: PMC3552518
Epa VC, Burden FR, Tassa C, Weissleder R, Shaw SY, Winkler DA
Modelling biological activities of nanoparticles.
Nano Lett. 2012;12(11):5808-5812 - PMID: 23039907
Keller TL, Zocco D, Sundrud MS, Hendrick M, Edenius M, Yum J, Kim YJ, Lee HK, Cortese JF, Wirth DF, Dignam JD, Rao A, Yeo CY, Mazitschek R, Whitman M
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase
Nat Chem Biol. 2012;8(3):311-7 - PMID: 22327401 - PMCID: PMC3281520
Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V
Evidence for bistable bacteria-neutrophil interaction and its clinical implications.
J Clin Invest. 2012;122(8):3002-11 - PMID: 22820292 - PMCID: PMC3408731
Lau KS, Cortez-Retamozo V, Philips SR, Pittet MJ, Lauffenburger DA, Haigis KM
Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium
PLoS Biol. 2012;10(9):e1001393 - PMID: 23055830 - PMCID: PMC3463506
Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
Gene Dev. 2012;26(24):2802-16 - PMID: 23249739 - PMCID: PMC3533082
Peterson VM, Castro CM, Lee H, Weissleder R
Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing.
ACS Nano. 2012;6(4):3506-13 - PMID: 22424443 - PMCID: PMC3337350
Min C, Shao H, Liong M, Yoon TJ, Weissleder R, Lee H
Mechanism of Magnetic Relaxation Switching Sensing.
ACS Nano. 2012;6(8):6821-8 - PMID: 22762250 - PMCID: PMC3429660
Nahrendorf M, McCarthy JR, Libby P
Over a hump for imaging atherosclerosis: nanobodies visualize vascular cell adhesion molecule-1 in inflamed plaque.
Circ Res. 2012;110(7):902-3 - PMID: 22461358
Courties G, Nahrendorf M
Enlightened stem cells in the heart: more efficient and safer reporter gene imaging.
Circ Res. 2012;111(12):1486-7 - PMID: 23223928
Chen CH, Miller MA, Sarkar A, Beste MT, Isaacson KB, Lauffenburger DA, Griffith LG, Han J
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis.
J Am Chem Soc. 2012;135(5):1645-8 - PMID: 23157326 - PMCID: PMC3566300
Agasti SS, Liong M, Peterson VM, Lee H, Weissleder R
Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cell.
J Am Chem Soc. 2012;134(45):18499-18502 - PMID: 23092113 - PMCID: PMC3498844
Niers JM*, Chen JW*, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA
Single Reporter for Targeted Multimodal in Vivo Imaging.
J Am Chem Soc. 2012;134(11):5149-56 - PMID: 22397453 - PMCID: PMC3310895
Mendenhall EM, Bernstein BE
DNA-protein interactions in high definition.
Genome Biol. 2012;13(1):139 - PMID: 22283870 - PMCID: PMC3334573
Ku M, Jaffe JD, Koche RP, Rheinbay E, Endoh M, Koseki H, Carr SA, Bernstein BE
H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions.
Genome Biol. 2012;13(10):R85 - PMID: 23034477 - PMCID: PMC3491413
Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivovarov M, Sbarbati A, Nahrendorf M, Weissleder R
Real-time in vivo imaging of the beating mouse heart at microscopic resolution
Nat Commun. 2012;3:1054 - PMID: 22968700 - PMCID: PMC3622400
Polasek M, Fuchs BC, Uppal R, Schühle DT, Alford JK, Loving GS, Yamada S, Wei L, Lauwers GY, Guimaraes AR, Tanabe KK, Caravan P
Molecular MR Imaging of Liver Fibrosis: A Feasibility Study using Rat and Mouse Models.
J Hepatol. 2012;57(3):549-55 - PMID: 22634342 - PMCID: PMC3423553
Lee S, Johnson TW, Lindquist NC, Im H, Norris DJ, Oh SH
Linewidth-Optimized Extraordinary Optical Transmission in Water with Template-Stripped Metallic Nanohole Arrays
Adv Funct Mater. 2012;22(21):4439-4446
Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ
Origins of tumor-associated macrophages and neutrophils.
Proc Natl Acad Sci U S A. 2012;109(7):2491-6 - PMID: 22308361 - PMCID: PMC3289379
Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M
Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.
Proc Natl Acad Sci U S A. 2012;109(27):E1868-77 - PMID: 22699504 - PMCID: PMC3390871
Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, Yarmush ML, Parekkadan B
Implantable microenvironments to attract hematopoietic stem/cancer cells.
Proc Natl Acad Sci U S A. 2012;109(48):19638-43 - PMID: 23150542 - PMCID: PMC3511730
Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R
Reactive polymer enables efficient in vivo bioorthogonal chemistry.
Proc Natl Acad Sci U S A. 2012;109(13):4762-7 - PMID: 22411831 - PMCID: PMC3324005
Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, Macdougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
Proc Natl Acad Sci U S A. 2012;109(52):21444-9 - PMID: 23236189 - PMCID: PMC3535589
Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, Roccaro AM, Sacco A, Ngo HT, Lin CP, Kung AL, Carrasco RD, Vanderkerken K, Ghobrial IM
Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features.
Blood. 2012;119(24):5782-94 - PMID: 22394600 - PMCID: PMC3382938
Santo L, Hideshima T, Kung AL, Tseng JC, Tamang D, Yang M, Jarpe M, van Duzer JH, Mazitschek R, Ogier WC, Cirstea D, Rodig S, Eda H, Scullen T, Canavese M, Bradner J, Anderson KC, Jones SS, Raje N
Preclinical activity, pharmacodynamic and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma.
Blood. 2012;119(11):2579-89 - PMID: 22262760 - PMCID: PMC3337713
Babitt JL, Lin HY
Mechanisms of Anemia in CKD.
J Am Soc Nephrol. 2012;23(10):1631-4 - PMID: 22935483 - PMCID: PMC3458456
Brown D, Wagner CA
Molecular Mechanisms of Acid-Base Sensing by the Kidney.
J Am Soc Nephrol. 2012;23(5):774-80 - PMID: 22362904 - PMCID: PMC3338302
Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA
Aquaporin 2 Promotes Cell Migration and Epithelial Morphogenesis.
J Am Soc Nephrol. 2012;23(9):1506-17 - PMID: 22859853 - PMCID: PMC3431417
Soehnlein O, Swirski FK
Hypercholesterolemia links hematopoiesis with atherosclerosis.
Trends Endocrin Met. 2012;24(3):129-136 - PMID: 23228326 - PMCID: PMC4302393
Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H
Magnetic Nanoparticles and microNMR for Diagnostic Applications.
Theranostics. 2012;2(1):55-65 - PMID: 22272219 - PMCID: PMC3263516
Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA,
A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force.
Cancer Res. 2012;72(24):6319-6324 - PMID: 23188507
Earley S, Vinegoni C, Dunham J, Gorbatov R, Fumene Feruglio P, Weissleder R
In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single cell resolution.
Cancer Res. 2012;72(12):2949-56 - PMID: 22505651 - PMCID: PMC3603290
Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H
Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity.
PLoS Genet. 2012;8(7):e1002774 - PMID: 22844243 - PMCID: PMC3405999
Bouley R
Corin: a key protein of an adaptive renal mechanism to respond to salt variation?
Kidney Int. 2012;82(1):7-8 - PMID: 22699378
Agasti SS, Kohler RH, Liong M, Peterson VM, Lee H, Weissleder R
Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking.
Small. 2012;9(2):222-7 - PMID: 22996932 - PMCID: PMC3552149
Hennings JC, Picard N, Huebner AK, Stauber T, Maier H, Brown D, Jentsch TJ, Vargas-Poussou R, Eladari D, Hübner CA
A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule.
EMBO Mol Med. 2012;4(10):1057-71 - PMID: 22933323 - PMCID: PMC3491836
Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG
Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics.
Biomaterials . 2012;33(20):5004-12 - PMID: 22494889 - PMCID: PMC3366278
Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, Aalberse R, Azumi A, Bloch DB, Brugge WR, Carruthers MN, Cheuk W, Cornell L, Castillo CF, Ferry JA, Forcione D, Klöppel G, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Masaki Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani D, Sato Y, Smyrk T, Stone JR, Takahira M, Umehara H, Webster G, Yamamoto M, Yi E, Yoshino T, Zamboni G, Zen Y, Chari S
IgG4-Related disease: recommendations for the nomenclature of this condition and its individual organ system manifestations.
Arthritis Rheum. 2012;64(10):3061-7 - PMID: 22736240
Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W
Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure.
Cell Rep. 2012;2(1):52-61 - PMID: 22840396 - PMCID: PMC3627357
Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, Romero P, Wurdinger T, Xavier RJ, Geissmann F, Meylan E, Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ
Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb
Cell Rep. 2012;1(4):1-8 - PMID: 22545247 - PMCID: PMC3334310
Mak AB, Nixon AM, Kittanakom S, Stewart JM, Chen GI, Curak J, Gingras AC, Mazitschek R, Neel BG, Stagljar I, Moffat J
Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation.
Cell Rep. 2012;2(4):951-63 - PMID: 23084749 - PMCID: PMC3590846
Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Mol Ther Nucleic Acids. 2012;1:e4 - PMID: 23344621 - PMCID: PMC3381593
Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL
Bevacizumab With Angiostatin-armed oHSV Increases Antiangiogenesis and Decreases Bevacizumab-induced Invasion in U87 Glioma.
Mol Ther. 2012;20(1):37-45 - PMID: 21915104 - PMCID: PMC3255598
Sosnovik DE, Nahrendorf M, Caravan P
Science to Practice: How Will Myocardial Inflammation Be Imaged with MR Imaging?
Radiology. 2012;264(2):309-11 - PMID: 22821689
Su HS, Nahrendorf M, Panizzi PR, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW
Vasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase.
Radiology. 2012;262(1):181-90 - PMID: 22084204 - PMCID: PMC3244672
Forghani R, Wojtkiewicz GR, Zhang Y, Seeburg D, Bautz BR, Pulli B, Milewski AR, Atkinson WL, Iwamoto Y, Zhang ER, Etzrodt M, Rodriguez E, Robbins CS, Swirski FK, Weissleder R, Chen JW
Demyelinating Diseases: Myeloperoxidase as an Imaging Biomarker and Therapeutic Target.
Radiology. 2012;263(2):451-60 - PMID: 22438365 - PMCID: PMC3329272
Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA
Inflammation Modulates Murine Venous Thrombosis Resolution In Vivo: Assessment by Multimodal Fluorescence Molecular Imaging.
Arterioscler Thromb Vasc Biol. 2012;32(11):2616-24 - PMID: 22995524 - PMCID: PMC3516622
Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH
Consensus statement on the pathology of IgG4-related disease.
Mod Pathol. 2012;25(9):1181-92 - PMID: 22596100
Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA
Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390
Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M
Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway.
JACC Cardiovasc Imaging. 2012;5(11):1127-38 - PMID: 23153913 - PMCID: PMC3502014
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY
On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics.
Lab Chip. 2012;12(17):3103-10 - PMID: 22760641 - PMCID: PMC3411869
Chen W, Sun CC, Chen S, Meynard D, Babitt JL, Lin HY
A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.
Haematologica. 2012;98(2):296-304 - PMID: 22875629 - PMCID: PMC3561439
Chung J*, Shao H*, Reiner T, Issadore D, Weissleder R, Lee H
Cell Sorting: Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells
Adv Healthc Mater. 2012;1(4):432-6 - PMID: 23184773 - PMCID: PMC3508764 - Cover
Sosnovik DE, Nahrendorf M
Cells and Iron Oxide Nanoparticles on the Move: Magnetic Resonance Imaging of Monocyte Homing and Myocardial Inflammation in Patients With ST-Elevation Myocardial Infarction.
Circ Cardiovasc Imaging. 2012;5(5):551-4 - PMID: 22991284 - PMCID: PMC3529959
Majmudar MD, Nahrendorf M
Cardiovascular Molecular Imaging: The Road Ahead.
J Nucl Med. 2012;53(5):673-676 - PMID: 22492729 - PMCID: PMC3744821
Mekkaoui C, Huang S, Chen HH, Dai G, Reese TG, Kostis WJ, Thiagalingam A, Maurovich-Horvat P, Ruskin JN, Hoffmann U, Jackowski MP, Sosnovik DE
Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation.
J Cardiovasc Magn Reson. 2012;14(1):70 - PMID: 23061749 - PMCID: PMC3506570
Im H, Sutherland JN, Maynard JA, Oh SH
Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics.
Anal Chem. 2012;84(4):1941-7 - PMID: 22235895 - PMCID: PMC3307221
Wittenberg NJ, Im H, Xu X, Wootla B, Watzlawik J, Warrington AE, Rodriguez M, Oh SH
High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance.
Anal Chem. 2012;84(14):6031-9 - PMID: 22762372 - PMCID: PMC3417152
Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R
Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents
Neoplasia. 2012;14(3):169-177 - PMID: 22496617 - PMCID: PMC3323895 - Cover
Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R
Sensitive and Direct Detection of Circulating Tumor Cells by Multimarker µ-Nuclear Magnetic Resonance.
Neoplasia. 2012;14(5):388-95 - PMID: 22745585 - PMCID: PMC3384426
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S
Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity.
ACS Chem Biol. 2012;7(9):1520-8 - PMID: 22724584
McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, Botnaru I, Lin CP, Reed GL, Weissleder R, Jaffer FA
Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy.
Nanomedicine (Lond). 2012;7(7):1017-28 - PMID: 22348271 - PMCID: PMC3360120
Unizony S, Stone JH, Stone JR
New treatment strategies in large-vessel vasculitis.
Curr Opin Rheumatol. 2012;25(1):3-9 - PMID: 23114585
Nahrendorf M
Macrophages in the infarct: fiery friends or friendly fire?
J Mol Cell Cardiol. 2012;53(5):591-2 - PMID: 22975014
Hilgendorf I, Swirski FK
Folate receptor: a macrophage "achilles' heel"?
J Am Heart Assoc. 2012;1(4):e004036 - PMID: 23130179 - PMCID: PMC3487350
Byun H, Hillman TR, Higgins JM, Diez-Silva M, Peng Z, Dao M, Dasari RR, Suresh S, Park Y
Optical measurement of biomechanical properties of individual erythrocytes from a sickle cell patient.
Acta Biomater. 2012;8(11):4130-8 - PMID: 22820310 - PMCID: PMC3576574
van der Laan AM, Nahrendorf M, Piek JJ
Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response.
Heart. 2012;98(18):1384-90 - PMID: 22904145
Ueno T, Yeung MY, McGrath M, Yang S, Zaman N, Snawder B, Padera RF, Magee CN, Gorbatov R, Hashiguchi M, Azuma M, Freeman GJ, Sayegh MH, Najafian N
Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses.
Eur J Immunol. 2012;42(9):2343-53 - PMID: 22733595 - PMCID: PMC3822046 - Cover
Miller M, Hafner M, Sontag E, Davidsohn N, Subramanian S, Purnick PE, Lauffenburger D, Weiss R
Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity.
PLoS Comput Biol. 2012;8(7):e1002579 - PMID: 22829755 - PMCID: PMC3400602
Lu X, Agasti SS, Vinegoni C, Waterman P, Depinho R, Weissleder R
Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators.
Bioconjug Chem. 2012;23(9):1945-51 - PMID: 22917215 - PMCID: PMC3775343
Brueckner C, Ogikubo J, McCarthy JR, Akhigbe J, Hyland MA, Daddario P, Worlinsky JL, Zeller M, Engle JT, Ziegler CJ, Ranaghan MJ, Sandberg MN, Birge RR
meso-Arylporpholactones and their Reduction Products.
J Org Chem. 2012;77(15):6480-94 - PMID: 22734444 - PMCID: PMC3411881
Cortez-Retamozo V, Etzrodt M, Pittet MJ
Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors.
J Innate Immunity. 2012;4(5-6):411-23 - PMID: 22433183 - PMCID: PMC3498093
Taqueti VR, Jaffer FA
High-resolution molecular imaging via intravital microscopy: illuminating vascular biology in vivo.
Integr Biol (Camb). 2012;5(2):278-90 - PMID: 23135362 - PMCID: PMC3558556
Ruan YC, Shum WW, Belleannée C, Da Silva N, Breton S
ATP secretion in the male reproductive tract: essential role of CFTR.
J Physiol. 2012;590(Pt 17):4209-22 - PMID: 22711960 - PMCID: PMC3473280
Rao SM, Auger JL, Gaillard P, Weissleder R, Wada E, Torres R, Kojima M, Benoist C, Mathis D, Binstadt BA
The neuropeptide neuromedin U promotes autoantibody-mediated arthritis.
Arthritis Res Ther. 2012;14(1):R29 - PMID: 22314006 - PMCID: PMC3392824
Kim JK, Vinarsky V, Wain JC, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH
In vivo imaging of tracheal epithelial cells in mice during airway regeneration.
Am J Respir Cell Mol Biol. 2012;47(6):864-8 - PMID: 22984086 - PMCID: PMC3547097
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ
Crebinostat: A Novel cognitive enhancer that inhibits Histone Deacetylase activity and Modulates Chromatin-mediated Neuroplasticity.
Neuropharmacology. 2012;64(1):81-96 - PMID: 22771460 - PMCID: PMC3447535
Krapf D, Chun Ruan Y, Wertheimer EV, Battistone MA, Pawlak JB, Sanjay A, Pilder SH, Cuasnicu P, Breton S, Visconti PE
cSrc is necessary for epididymal development and is incorporated into sperm during epididymal transit.
Dev Biol. 2012;369(1):43-53 - PMID: 22750823 - PMCID: PMC3424100
Unizony S, Arias-Urdaneta L, Miloslavsky E, Arvikar S, Khosroshahi A, Keroack B, Stone J, Stone J
Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, takayasu arteritis) and polymyalgia rheumatica.
Arthritis Care Res (Hoboken). 2012;64(11):1720-9 - PMID: 22674883
Vinegoni C, Feruglio PF, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R
Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography.
PLoS ONE. 2012;7(4):e34427 - PMID: 22509302 - PMCID: PMC3324534
Wu X, Yung LM, Cheng WH, Yu PB, Babitt JL, Lin HY, Xia Y
Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent.
PLoS ONE. 2012;7(9):e44622 - PMID: 23028567 - PMCID: PMC3441567
Chong NW, Koekemoer AL, Ounzain S, Samani NJ, Shin JT, Shaw SY
STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway.
PLoS ONE. 2012;7(7):e40966 - PMID: 22815879 - PMCID: PMC3399798
Atkinson W*, Forghani R*, Wojtkiewicz GR, Pulli B, Iwamoto Y, Ueno T, Waterman P, Truelove J, Oklu R, Chen JW
Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice
PLoS ONE. 2012;7(3):e33671 - PMID: 22457780 - PMCID: PMC3310075
Rice WL, Zhang Y, Chen Y, Matsuzaki T, Brown D, Lu HA
Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells.
PLoS ONE. 2012;7(2):e32843 - PMID: 22403603 - PMCID: PMC3293519
Miller MA, Feng XJ, Li G, Rabitz HA
Identifying biological network structure, predicting network behavior, and classifying network state with High Dimensional Model Representation (HDMR).
PLoS ONE. 2012;7(6):e37664 - PMID: 22723838 - PMCID: PMC3377689
Wu Q, Sun CC, Lin HY, Babitt JL
Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs).
PLoS ONE. 2012;7(9):e46307 - PMID: 23029472 - PMCID: PMC3459908
Staropoli JF, Haliw L, Biswas S, Garrett L, Hölter SM, Becker L, Skosyrski S, Da Silva-Buttkus P, Calzada-Wack J, Neff F, Rathkolb B, Rozman J, Schrewe A, Adler T, Puk O, Sun M, Favor J, Racz I, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Wolf E, Wurst W, Zimmer A, Lopez E, Harati H, Hill E, Krause DS, Guide J, Dragileva E, Gale E, Wheeler VC, Boustany RM, Brown DE, Breton S, Ruether K, Gailus-Durner V, Fuchs H, de Angelis MH, Cotman SL
Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System.
PLoS ONE. 2012;7(6):e38310 - PMID: 22701626 - PMCID: PMC3368842
Păunescu TG, Rodriguez S, Benz E, McKee M, Tyszkowski R, Albers MW, Brown D
Loss of the V-ATPase B1 Subunit Isoform Expressed in Non-Neuronal Cells of the Mouse Olfactory Epithelium Impairs Olfactory Function.
PLoS ONE. 2012;7(9):e45395 - PMID: 23028982 - PMCID: PMC3447883
Brown D, Bouley R, Paunescu TG, Breton S, Lu HA
New insights into the dynamic regulation of water and acid/base balance by renal epithelial cells.
Am J Physiol Cell Physiol. 2012;302(10):C1421-33 - PMID: 22460710 - PMCID: PMC3362000
Yui N, Lu HA, Chen Y, Nomura N, Bouley R, Brown D
Basolateral targeting and microtubule dependent transcytosis of the aquaporin-2 water channel.
Am J Physiol Cell Physiol. 2012;304(1):C38-48 - PMID: 23015545 - PMCID: PMC3543574
Vedovelli L, Rothermel JT, Finberg KE, Wagner CA, Azroyan A, Hill E, Breton S, Brown D, Paunescu TG
Altered V-ATPase expression in renal intercalated cells isolated from B1-subunit deficient mice by fluorescence activated cell sorting.
Am J Physiol Renal Physiol. 2012;304(5):F522-32 - PMID: 23269648 - PMCID: PMC3602708
Bouley R, Nunes P, Andriopoulos B, McLaughlin MM, Webber MJ, Lin HY, Babitt JL, Gardella TJ, Ausiello DA, Brown D
Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.
Am J Physiol Renal Physiol. 2012;304(5):F553-64 - PMID: 23235478 - PMCID: PMC3602717
Heidt T, Nahrendorf M
Multimodal iron oxide nanoparticles for hybrid biomedical imaging.
NMR Biomed. 2012;26(7):756-65 - PMID: 23065771 - PMCID: PMC3549036
Wang K, Liu TM, Wu J, Horton NG, Lin CP, Xu C
Three-color femtosecond source for simultaneous excitation of three fluorescent proteins in two-photon fluorescence microscopy.
Biomed Opt Express. 2012;3(9):1972-7 - PMID: 23024893 - PMCID: PMC3447541
Waters JD, Sanchez C, Sahin A, Futalan D, Gonda DD, Scheer JK, Akers J, Palanichamy K, Waterman P, Chakravarti A, Weissleder R, Morse B, Marsh N, Furfine E, Chen CC, Carvajal I, Carter BS
CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy.
J Neurooncol. 2012;110(1):37-48 - PMID: 22875706 - PMCID: PMC4291475
Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R
Noise suppressed, multifocus image fusion for enhanced intraoperative navigation.
J Biophotonics. 2012;6(4):363-70 - PMID: 22887724 - PMCID: PMC3779878
Derbyshire ER, Mazitschek R, Clardy J
Characterization of Plasmodium Liver Stage Inhibition by Halofuginone.
ChemMedChem. 2012;7(5):844-9 - PMID: 22438279 - PMCID: PMC3359061 - Cover
Hilgendorf I, Swirski FK
Making a Difference: Monocyte Heterogeneity in Cardiovascular Disease.
Curr Atheroscler Rep. 2012;14(5):450-9 - PMID: 22847772 - PMCID: PMC3436972
Elmi A, Tabatabaei S, Talab SS, Hedgire SS, Cao K, Harisinghani M
Incidental findings at initial imaging workup of patients with prostate cancer: clinical significance and outcomes.
AJR Am J Roentgenol. 2012;199(6):1305-11 - PMID: 23169722
Duigenan S, Gee MS
Imaging of pediatric patients with inflammatory bowel disease.
AJR Am J Roentgenol. 2012;199(4):907-15 - PMID: 22997386
Robbins CS, Swirski FK
Newly discovered innate response activator B cells: crucial responders against microbial sepsis.
Expert Rev Clin Immunol. 2012;8(5):405-7 - PMID: 22882214
Zettergren E, Vickers D, Runnels J, Murthy SK, Lin CP, Niedre M
Instrument for fluorescence sensing of circulating cells with diffuse light in mice in vivo.
J Biomed Opt. 2012;17(3):037001 - PMID: 22502573 - PMCID: PMC3380949
Lee S, Vinegoni C, Feruglio PF, Weissleder R
Improved intravital microscopy via synchronization of respiration and holder stabilization.
J Biomed Opt. 2012;17(9):96018-1 - PMID: 23085919 - PMCID: PMC3449295
Kim Y, Higgins JM, Dasari RR, Suresh S, Park Y
Anisotropic light scattering of individual sickle red blood cells.
J Biomed Opt. 2012;17(4):040501 - PMID: 22559667 - PMCID: PMC3602817
Liu X, Nielsen GP, Rosenberg AE, Waterman PR, Yang W, Choy E, Sassi S, Yang S, Harmon DC, Yang C, Schwab JH, Kobayashi E, Mankin HJ, Xavier R, Weissleder R, Duan Z, Hornicek FJ
Establishment and characterization of a novel chordoma cell line: CH22.
J Orthop Res. 2012;30(10):1666-73 - PMID: 22504929
Saxena A, Kessinger CW, Thompson B, McCarthy JR, Iwamoto Y, Lin CP, Jaffer FA
High-Resolution Optical Mapping of Inflammatory Macrophages Following Endovascular Arterial Injury.
Mol Imaging Biol. 2012;15(3):282-9 - PMID: 23090852 - PMCID: PMC3650124
Lin HY
Transforming Growth Factor-β and the Kidney Revisited: Introduction.
Semin Nephrol. 2012;32(3):225-7 - PMID: 22835452
Sahani DV, Bonaffini PA, Catalano OA, Guimaraes AR, Blake MA
State-of-the-Art PET/CT of the Pancreas: Current Role and Emerging Indications.
Radiographics. 2012;32(4):1133-58 - PMID: 22786999
Zettergren E, Swamy T, Runnels J, Lin CP, Niedre M
Tomographic sensing and localization of fluorescently labeled circulating cells in mice in vivo.
Phys Med Biol. 2012;57(14):4627-41 - PMID: 22750660 - PMCID: PMC3555500
Razansky D, Deliolanis N, Vinegoni C, Ntziachristos V
Deep Tissue Optical and Optoacoustic Molecular Imaging Technologies for Small Animal Research and Drug Discovery.
Curr Pharm Biotechnol. 2012;13(4):504-22 - PMID: 22216767
Gutiérrez OM, Sun CC, Chen W, Babitt JL, Lin HY
Statement of Concern about a Commercial Assay Used to Measure Soluble Hemojuvelin in Humans.
Am J Nephrol. 2012;36(4):332-333 - PMID: 23006450
Siddiquee Z, Zane NA, Smith RN, Stone JR
Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease.
Cardiovasc Pathol. 2012;21(6):470-5 - PMID: 22406174
McDermott S, Hedgire SS, Hahn PF, Mueller PR, Harisinghani MG
Image-Guided Biopsy of Suspicious Lymph Nodes in Patients with Known Primary Malignancies.
J Vasc Interv Radiol. 2012;23(3):371-6 - PMID: 22265244
Erdem SS, Sazonova IY, Hara T, Jaffer FA, McCarthy JR
Detection and treatment of intravascular thrombi with magnetofluorescent nanoparticles.
Method Enzymol. 2012;508:191-209 - PMID: 22449927
Hedgire SS, Pargaonkar VK, Elmi A, Harisinghani AM, Harisinghani MG
Pelvic nodal imaging.
Radiol Clin North Am. 2012;50(6):1111-25 - PMID: 23122041
Hartman RI, Chang CY, Wo JY, Eisenberg JD, Hong TS, Harisinghani MG, Gazelle GS, Pandharipande PV
Optimizing Adjuvant Treatment Decisions for Stage T2 Rectal Cancer Based on Mesorectal Node Size: A Decision Analysis.
Acad Radiol. 2012;20(1):79-89 - PMID: 22947271 - PMCID: PMC3525763
Dip PV, Saw WG, Roessle M, Marshansky V, Grüber G
Solution structure of subunit a, a (104-363), of the Saccharomyces cerevisiae V-ATPase and the importance of its C-terminus in structure formation.
J Bioenerg Biomembr. 2012;44(3):341-50 - PMID: 22562380
Dejesus Allison SO, Javitt MC, Glanc P, Andreotti RF, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Mitchell DG, Pandharipande PV, Pannu HK, Podrasky AE, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM
ACR Appropriateness Criteria® Multiple Gestations.
Ultrasound Q. 2012;28(2):149-155 - PMID: 22634795
Fradley MG, Thakuria JV, Collins AB, Moore SA, Stone JR
Direct Tissue Evaluation via Immunofluorescence: in the Diagnosis of Hereditary Transthyretin Cardiac Amyloidosis.
Tex Heart I J. 2012;39(1):71-5 - PMID: 22412233 - PMCID: PMC3298917
Hedgire SS, Elmi A, Nadkarni ND, Cao K, McDermott S, Harisinghani MG
Preoperative evaluation of perinephric fat invasion in patients with renal cell carcinoma: correlation with pathological findings.
Clin Imaging. 2012;37(1):91-6 - PMID: 23206613
Yui N, Lu HJ, Bouley R, Brown D
AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells.
Biol Open. 2012;1(2):101-8 - PMID: 23213402 - PMCID: PMC3507199
Hedgire SS, Oei TN, McDermott S, Cao K, Patel M Z, Harisinghani MG
Multiparametric magnetic resonance imaging of prostate cancer.
Indian J Radiol Imaging. 2012;22(3):160-9 - PMID: 23599562 - PMCID: PMC3624737
Keliher EJ, Reiner T, Thurber GM, Upadhyay R, Weissleder R
Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells.
ChemistryOpen. 2012;1(4):177-183 - PMID: 23997998 - PMCID: PMC3758109
Vinegoni C, Lee S, Gorbatov R, Weissleder R
Motion compensation using a suctioning stabilizer for intravital microscopy
Intravital. 2012;1:115-121 - PMID: 24086796 - PMCID: PMC3786172
Phillips JA, Mortensen LJ, Ruiz JP, Sridharan R, Kumar S, Torres M, Sharma P, Lin CP, Karp JM, Hauschka PV
Advances in Single-cell Tracking of Mesenchymal Stem Cells (MSCs) During Musculoskeletal Regeneration.
Orthop J Harv Med Sch. 2012;14:22-28 - PMID: 24244929 - PMCID: PMC3824625
Rosenthal A, Jaffer FA, Ntziachristos V
Intravascular multispectral optoacoustic tomography of atherosclerosis: prospects and challenges.
Imaging Med. 2012;4(3):299-310 - PMID: 23144663 - PMCID: PMC3493570
Alt C, Runnels J, Teo G, Lin C
In vivo tracking of hematopoietic cells in the retina of chimeric mice with a scanning laser ophthalmoscope
Intravital. 2012;1:132-140
Stone JR
Diagnostic Biopsies of the Native Heart.
Surg Pathol Clin. 2012;5(2):401-16 - PMID: 26838110
Im H, Wittenberg NJ, Lindquist NC, Oh SH
Atomic layer deposition (ALD): A versatile technique for plasmonics and nanobiotechnology.
J Mater Res. 2012;27(4):663-671 - PMID: 22865951 - PMCID: PMC3410655
Kaufman DS, Zietman AL, Dahl DM, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 5-2011. A 65-year-old man with hematuria after treatment for prostate cancer.
New Engl J Med. 2011;364(7):667-75 - PMID: 21323545
Karchmer AW, MacGillivray TE, Healey TT, Stone JR
Case records of the Massachusetts General Hospital. Case 1-2011. A 35-year-old man with fever, bacteremia, and a mass in the left atrium.
New Engl J Med. 2011;364(2):158-66 - PMID: 21226582
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Celso CL, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP
In vivo imaging of T(reg) cells providing immune privilege to the haematopoietic stem-cell niche.
Nature. 2011;474(7350):216-9 - PMID: 21654805 - PMCID: PMC3725645
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR
Initial genome sequencing and analysis of multiple myeloma.
Nature. 2011;471(7339):467-72 - PMID: 21430775 - PMCID: PMC3560292
Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE
Mapping and analysis of chromatin state dynamics in nine human cell types.
Nature. 2011;473(7345):43-9 - PMID: 21441907 - PMCID: PMC3088773
Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M
Therapeutic siRNA silencing in inflammatory monocytes in mice
Nat Biotechnol. 2011;29(11):1005-10 - PMID: 21983520 - PMCID: PMC3212614
Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE
Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells.
Cell. 2011;147(7):1628-39 - PMID: 22196736 - PMCID: PMC3312319
Pittet MJ, Weissleder R
Intravital imaging.
Cell. 2011;147(5):983-91 - PMID: 22118457 - PMCID: PMC3824153
Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains.
Cell. 2011;144(4):513-25 - PMID: 21335234 - PMCID: PMC3572774
Walhout AJM, Aebersold R, Meyer T, Bork P, Kirschner MW
Systems Biology: What's the Next Challenge?
Cell. 2011;144:6
Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM
Cell-surface sensors for real-time probing of cellular environments.
Nat Nanotechnol. 2011;6(8):524-31 - PMID: 21765401 - PMCID: PMC3163485
Panizzi P*, Nahrendorf M*, Jose-Luiz Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation
Nature Med. 2011;17(9):1142-6 - PMID: 21857652 - PMCID: PMC3169740
Yoo H, Kim JW, Shishkov M, Namati E, Morse T, Shubochkin R, McCarthy JR, Ntziachristos V, Bouma BE, Jaffer FA, Tearney GJ
Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo.
Nature Med. 2011;17(12):1680-4 - PMID: 22057345 - PMCID: PMC3233646
Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A
Reprogramming factor expression initiates widespread targeted chromatin remodeling.
Cell Stem Cell. 2011;8(1):96-105 - PMID: 21211784 - PMCID: PMC3220622
Tassa C, Shaw SY, Weissleder R
Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy.
Accounts Chem Res. 2011;44(10):842-52 - PMID: 21661727 - PMCID: PMC3182289
Devaraj NK, Weissleder R
Biomedical Applications of Tetrazine Cycloadditions.
Accounts Chem Res. 2011;44(9):816-27 - PMID: 21627112 - PMCID: PMC3166440
Atri M, Zhang Z, Marques H, Gorelick J, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Gold M,
Utility of preoperative ferumoxtran-10 enhanced MRI to evaluate retroperitoneal lymph node metastasis in advanced cervical cancer: Results of ACRIN 6671/GOG 0233.
J Clin Oncol. 2011;29(15_suppl):5035 - PMID: 28023716
Gold M, Zhang Z, Marques H, Gorelick J, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Atri M
MRI prior to systematic lymphadenectomy in patients with locally advanced cervical cancer.
J Clin Oncol. 2011;29(15_suppl):5042 - PMID: 28023697
Santo L, Hideshima T, Kung AL, Yang M, Tamang D, Jarpe M, van Duzer JH, Mazitschek R, Cirstea D, Patel K, Tseng J, Rodig S, Pozzi S, Bradner J, Anderson KC, Jones SS, Raje NS
The effect of selective inhibition of HDAC6 with ACY1215 on bortezomib activity in multiple myeloma (MM).
J Clin Oncol. 2011;29(15_suppl):e18569 - PMID: 28023028
Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Sci Transl Med. 2011;3(104):104ra101 - PMID: 21998408 - PMCID: PMC3754876
Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA
Indocyanine Green Enables Near-Infrared Fluorescence Imaging of Lipid-Rich, Inflamed Atherosclerotic Plaques
Sci Transl Med. 2011;3 (84) ra45):84ra45 - PMID: 21613624 - PMCID: PMC3112179
Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R.
Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples
Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - Cover
Shaw SY, Brettman AD
Phenotyping patient-derived cells for translational studies in cardiovascular disease.
Circulation. 2011;124(22):2444-55 - PMID: 22125190 - PMCID: PMC3263367
Robbins CS, Chudnovskiy A, Rauch PJ, Figueiredo JL, Iwamoto Y, Gorbatov R, Etzrodt M, Weber GF, Ueno T, van Rooijen N, Mulligan-Kehoe MJ, Libby P, Nahrendorf M, Pittet MJ, Weissleder R, Swirski FK
Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes that Infiltrate Atherosclerotic Lesions.
Circulation. 2011;125(2):364-74 - PMID: 22144566 - PMCID: PMC3263762
Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R
Report of the national heart, lung, and blood institute working group on the translation of cardiovascular molecular imaging.
Circulation. 2011;123(19):2157-63 - PMID: 21576680 - PMCID: PMC3119488
Yoon TJ*, Lee H*, Shao H, Hilderbrand SA, Weissleder R
Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles.
Adv Mater. 2011;23(41):4793-7 - PMID: 21953810 - PMCID: PMC3224986
Liong M, Tassa C, Shaw SY, Lee H, Weissleder R
Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization.
Adv Mater. 2011;23(36):H254-7 - PMID: 21780311 - PMCID: PMC3584698
Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V
Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury.
J Am Coll Cardiol. 2011;57(25):2516-26 - PMID: 21679853 - PMCID: PMC3123768
Yoon TJ*, Lee H*, Shao H, Weissleder R
Highly magnetic core-shell nanoparticles with a unique magnetization mechanism.
Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859
Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R
Synthesis and In Vivo Imaging of a (18) F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method.
Angew Chem Int Ed Engl. 2011;50(8):1922-5 - PMID: 21328671 - PMCID: PMC3471140
Budin G, Yang KS, Reiner T, Weissleder R
Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification.
Angew Chem Int Ed Engl. 2011;50(40):9378-81 - PMID: 21948435 - PMCID: PMC3187564
Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R
Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers.
Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171
Karver MR, Weissleder R, Hilderbrand SA
Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging.
Angew Chem Int Ed Engl. 2011;51(4):920-2 - PMID: 22162316 - PMCID: PMC3304098
Ghosh K, Kanapathipillai M, Korin N, McCarthy JR, Ingber D
Polymeric Nanomaterials for Islet Targeting and Immunotherapeutic Delivery.
Nano Lett. 2011;12(1):203-8 - PMID: 22196766 - PMCID: PMC3280082
Shah K
Mesenchymal stem cells engineered for cancer therapy.
Adv Drug Deliv Rev. 2011;64(8):739-48 - PMID: 21740940 - PMCID: PMC3395998
Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE
Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
Gastroenterology. 2011;141(5):1907-14 - PMID: 21745449 - PMCID: PMC3634343
Wittenberg NJ, Im H, Johnson TW, Xu X, Warrington AE, Rodriguez M, Oh SH
Facile assembly of micro- and nanoarrays for sensing with natural cell membranes.
ACS Nano. 2011;5(9):7555-64 - PMID: 21842844 - PMCID: PMC3183111
Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R
Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells.
ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118
Haun J, Devaraj NK, Marinelli B, Lee H, Weissleder R
Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry.
ACS Nano. 2011;5(4):3204-13 - PMID: 21351804 - PMCID: PMC3088084
Im H, Lee SH, Wittenberg NJ, Johnson TW, Lindquist NC, Nagpal P, Norris DJ, Oh SH
Template-stripped smooth Ag nanohole arrays with silica shells for surface plasmon resonance biosensing.
ACS Nano. 2011;5(8):6244-53 - PMID: 21770414 - PMCID: PMC3160512
Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R
Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles.
ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727
Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, Babitt JL
Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice.
Hepatology. 2011;54(1):273-84 - PMID: 21488083 - PMCID: PMC3277401
Leuschner F, Nahrendorf M
Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic.
Circ Res. 2011;108(5):593-606 - PMID: 21372291 - PMCID: PMC3397211 - Cover
Brueckner C, Gotz DC, Fox SP, Ryppa C, McCarthy JR, Bruhn T, Akhigbe J, Banerjee S, Daddario P, Daniell HW, Zeller M, Boyle R, Bringmann G
Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins.
J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626
Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator.
J Am Chem Soc. 2011;133(27):10368-71 - PMID: 21671557 - PMCID: PMC3165005
Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A
IKKb regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.
Nat Commun. 2011;2:318 - PMID: 21587235 - PMCID: PMC3113230
Shi P, Scott MA, Ghosh B, Wan D, Wissner-Gross Z, Mazitschek R, Haggarty SJ, Yanik MF
Synapse microarray identification of small molecules that enhance synaptogenesis.
Nat Commun. 2011;2:510 - PMID: 22027590 - PMCID: PMC3544154
Ladapo JA, Jaffer FA, Weinstein MC, Froelicher ES
Projected Cost-effectiveness of Smoking Cessation Interventions in Patients Hospitalized With Myocardial Infarction.
Arch Intern Med. 2011;171(1):39-45 - PMID: 21220659
Grover WH, Bryan AK, Diez-Silva M, Suresh S, Higgins JM, Manalis SR
Measuring single-cell density.
Proc Natl Acad Sci U S A. 2011;108(27):10992-10996 - PMID: 21690360 - PMCID: PMC3131325
Zhao B, Zou J, Wang H, Johannsen E, Peng CW, Quackenbush J, Mar JC, Morton CC, Freedman ML, Blacklow SC, Aster JC, Bernstein BE, Kieff E
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth.
Proc Natl Acad Sci U S A. 2011;108(36):14902-7 - PMID: 21746931 - PMCID: PMC3169132
Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R
Accurate measurement of pancreatic islet {beta}-cell mass using a second-generation fluorescent exendin-4 analog.
Proc Natl Acad Sci U S A. 2011;108(31):12815-20 - PMID: 21768367 - PMCID: PMC3150928
Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells.
Proc Natl Acad Sci U S A. 2011;108(36):14908-13 - PMID: 21737748 - PMCID: PMC3169118
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801
Maiso P, Liu Y, Morgan B, Azab A, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro A, Rommel C, Ghobrial IM
Defining the role of TORC1 and TORC2 in multiple myeloma.
Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208
Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment.
Blood. 2011;119(6):1468-78 - PMID: 22096244 - PMCID: PMC3286211
Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM
Engineered cell homing.
Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725
Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats.
Blood. 2011;118(18):4977-84 - PMID: 21730356 - PMCID: PMC3208302
Meynard D, Vaja V, Sun CC, Corradini E, Chen S, Lopez-Otin C, Grgurevic L, Hong CC, Stirnberg M, Gutschow M, Vukicevic S, Babitt JL, Lin HY
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.
Blood. 2011;118(3):747-56 - PMID: 21622652 - PMCID: PMC3142910
Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ
Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics.
Cancer Res. 2011;71(13):4608-16 - PMID: 21712408 - PMCID: PMC3129392
Ziller MJ, Müller F, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A
Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types.
PLoS Genet. 2011;7(12):e1002389 - PMID: 22174693 - PMCID: PMC3234221
Babitt JL, Lin HY
The molecular pathogenesis of hereditary hemochromatosis.
Semin Liver Dis. 2011;31(3):280-92 - PMID: 21901658
Adli M, Bernstein BE
Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq.
Nat Protoc. 2011;6(10):1656-68 - PMID: 21959244 - PMCID: PMC4493313
Kleijn A*, Chen JW*, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G
Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.
Clin Cancer Res. 2011;17(13):4484-93 - PMID: 21558403 - PMCID: PMC3131449
Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, Macdonald ME, Seong IS
Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Hum Mol Genet. 2011;20(12):2344-55 - PMID: 21447599 - PMCID: PMC3098733
Wang H, Smith RN, Spooner AE, Isselbacher EM, Cambria RP, Macgillivray TE, Stone JH, Stone JR
Giant cell aortitis of the ascending aorta without signs or symptoms of systemic vasculitis is associated with elevated risk of distal aortic events.
Arthritis Rheum. 2011;64(1):317-9 - PMID: 21953530
Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA
The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling.
J Neurosci. 2011;31(50):18391-18400 - PMID: 22171041 - PMCID: PMC3243947
Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ
Genetic and Clinical Correlates of Early Outgrowth Colony Forming Units.
Circ Cardiovasc Genet. 2011;4(3):296-304 - PMID: 21493818 - PMCID: PMC3339257
Nahrendorf M, Sosnovik DE
Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging?
Radiology. 2011;260(2):309-10 - PMID: 21778448
Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R
Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography-Computed Tomography.
Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - Cover
Swirski FK
The spatial and developmental relationships in the macrophage family.
Arterioscler Thromb Vasc Biol. 2011;31(7):1517-22 - PMID: 21677294 - PMCID: PMC3117206
Kim DE, Kim JY, Nahrendorf M, Lee SK, Ryu JH, Kim K, Kwon IC, Schellingerhout D
Direct Thrombus Imaging as a Means to Control the Variability of Mouse Embolic Infarct Models: The Role of Optical Molecular Imaging.
Stroke. 2011;42(12):3566-73 - PMID: 22020025
Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.
Chem Biol. 2011;18(12):1602-10 - PMID: 22195562 - PMCID: PMC3474356
Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P
Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo.
Thromb Haemostasis. 2011;105(5):828-36 - PMID: 21225096 - PMCID: PMC3087830
Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H
Miniature magnetic resonance system for point-of-care diagnostics.
Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660
Nordbeck P, Hiller KH, Fidler F, Warmuth M, Burkard N, Nahrendorf M, Jakob PM, Quick HH, Ertl G, Bauer WR, Ritter O
Feasibility of Contrast Enhanced and Non-Enhanced MRI for Intra- and Postprocedural Lesion Visualization in Interventional Electrophysiology: Animal Studies and Early Delineation of Isthmus Ablation Lesions in Patients with Typical Atrial Flutter.
Circ Cardiovasc Imaging. 2011;4(3):282-94 - PMID: 21415125
Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE
Molecular MRI of Acute Necrosis with a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium.
Circ Cardiovasc Imaging. 2011;4(6):729-737 - PMID: 21836081 - PMCID: PMC3370828
Nahrendorf M
Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity.
Circ Cardiovasc Imaging. 2011;4(4):351-3 - PMID: 21772011 - PMCID: PMC3141180
Niers JM, Chen JW, Weissleder R, Tannous BA
Enhanced in Vivo Imaging of Metabolically Biotinylated Cell Surface Reporters.
Anal Chem. 2011;83(3):994-9 - PMID: 21214190 - PMCID: PMC3059349
Hendricks JA, Keliher EJ, Marinelli B, Reiner T, Weissleder R, Mazitschek R
In Vivo PET-imaging of Histone Deacetylases by 18F-Suberoylanilide Hydroxamic Acid (18F-SAHA).
J Med Chem. 2011;54(15):5576-82 - PMID: 21721525 - PMCID: PMC3150598
Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, Wu MX
FTY720 Blocks Egress of T Cells in Part by Abrogation of Their Adhesion on the Lymph Node Sinus.
J Immunol. 2011;187(5):2244-51 - PMID: 21788441 - PMCID: PMC3167479
Riella LV*, Ueno T*, Batal I, De Serres SA, Bassil R, Elyaman W, Yagita H, Medina-Pestana JO, Chandraker A, Najafian N
Blockade of notch ligand delta1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation.
J Immunol. 2011;187(9):4629-38 - PMID: 21949024 - PMCID: PMC3197868
Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY
Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages.
J Immunol. 2011;186(3):1369-76 - PMID: 21187450 - PMCID: PMC3670585
de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW
HDAC6 and HSP90 Control The Functions Of Foxp3+ T-Regulatory Cells.
Mol Cell Biol. 2011;31(10):2066-78 - PMID: 21444725 - PMCID: PMC3133361
Chen HH, Feng Y, Zhang M, Chao W, Josephson L, Shaw SY, Sosnovik DE
Protective Effect of the Apoptosis-Sensing Nanoparticle AnxCLIO-Cy5.5.
Nanomedicine (Lond). 2011;8(3):291-298 - PMID: 21704591 - PMCID: PMC3319055
Weissleder R, Castro C
Interview: Nanomedicine in oncology: miniaturized means to an enormous end.
Nanomedicine (Lond). 2011;6(9):1495-8 - PMID: 22077461
McCarthy JR, Jaffer FA
The role of nanomedicine in the imaging and therapy of thrombosis.
Nanomedicine (Lond). 2011;6(8):1291-3 - PMID: 22026372 - PMCID: PMC3332076
Wang L, Trebicka E, Fu Y, Ellenbogen S, Hong CC, Babitt JL, Lin HY, Cherayil BJ
The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease.
Inflamm Bowel Dis. 2011;18(1):112-9 - PMID: 21351217 - PMCID: PMC3139830
Pittet MJ, Swirski FK
Monocytes link atherosclerosis and cancer.
Eur J Immunol. 2011;41(9):2519-22 - PMID: 21952809 - PMCID: PMC3817567
Chen S, Webber MJ, Vilardaga JP, Khatri A, Brown D, Ausiello DA, Lin HY, Bouley R
Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand.
Endocrinology. 2011;152(10):3893-904 - PMID: 21828182 - PMCID: PMC3176653
Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Frohlich LF, Bastepe M
Transgenic Overexpression of the Extra-Large Gs{alpha} Variant XL{alpha}s Enhances Gs{alpha}-Mediated Responses in the Mouse Renal Proximal Tubule in Vivo.
Endocrinology. 2011;152(4):1222-33 - PMID: 21303955 - PMCID: PMC3060637
Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW
ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
J Biol Chem. 2011;286(47):40443-51 - PMID: 21956108 - PMCID: PMC3220463
Li Y, Si R, Feng Y, Chen HH, Zou L, Wang E, Zhang M, Warren HS, Sosnovik DE, Chao W
Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4.
J Biol Chem. 2011;286(36):31308-19 - PMID: 21775438 - PMCID: PMC3173057
Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R
Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance.
Bioconjug Chem. 2011;22(12):2390-4 - PMID: 22043803 - PMCID: PMC3263317
Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS
A Modular Strategy for the Construction of Radiometallated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels-Alder Click Chemistry.
Bioconjug Chem. 2011;22(10):2048-59 - PMID: 21877749 - PMCID: PMC3197258
Keliher E, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet M, Weissleder R
89Zr Labeled Dextran Nanoparticles Enable in vivo Macrophage Imaging.
Bioconjug Chem. 2011;22(12):2383-9 - PMID: 22035047 - PMCID: PMC3244512
Karver M, Weissleder R, Hilderbrand SA
Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation.
Bioconjug Chem. 2011;22(11):2263-2270 - PMID: 21950520 - PMCID: PMC3254257
Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jimenez-Diaz MB, Magan N, Gomez V, Ferrer S, Santos Marti
Aminoindoles: a Novel Scaffold with Potent Activity against Plasmodium falciparum.
Antimicrob Agents Chemother. 2011;55(6):2612-22 - PMID: 21422215 - PMCID: PMC3101419
Kirsch DG, Grimm J, Guimaraes AR, Weissleder R
In response to dr. Garbow and colleagues.
Int J Radiat Oncol Biol Phys. 2011;79(3):959 - PMID: 21281902
Sun CC, Vaja V, Babitt JL, Lin HY
Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation.
Am J Hematol. 2011;87(4):392-400 - PMID: 22290531 - PMCID: PMC3653431
Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA
Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex.
Clin Genet. 2011;82(6):558-63 - PMID: 22035404
Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM
Nanoparticle-based monitoring of cell therapy.
Nanotechnology. 2011;22(49):494001 - PMID: 22101191 - PMCID: PMC3334527
Ueno T, Yamada A, Ito T, Yeung MY, Gorbatov R, Shimizu T, Abdi R, Sayegh MH, Auchincloss H, Najafian N
Role of Nuclear Factor of Activated T Cell (NFAT) Transcription Factors in Skin and Vascularized Cardiac Allograft Rejection.
Transplantation. 2011;92(5):e26-e27 - PMID: 21866037
Settles M, Etzrodt M, Kosanke K, Schiemann M, Zimmermann A, Meier R, Braren R, Huber A, Rummeny EJ, Weissleder R, Swirski FK, Wildgruber M
Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles.
PLoS ONE. 2011;6(10):e25197 - PMID: 21984904 - PMCID: PMC3184946
Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG
BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin.
PLoS ONE. 2011;6(1):e14553 - PMID: 21283739 - PMCID: PMC3024971
Ryan RJ, Nitta M, Borger D, Zukerberg LR, Ferry JA, Harris NL, Iafrate AJ, Bernstein BE, Sohani AR, Le LP
EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas.
PLoS ONE. 2011;6(12):e28585 - PMID: 22194861 - PMCID: PMC3237460
Thurber GM, Weissleder R
A Systems Approach for Tumor Pharmacokinetics
PLoS ONE. 2011;6(9):e24696 - PMID: 21935441 - PMCID: PMC3173470
Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP
Cell labeling approaches for fluorescence-based in vivo flow cytometry.
Cytometry A. 2011;79(10):758-65 - PMID: 21905206 - PMCID: PMC3686107
Merkulova M, Hurtado-Lorenzo A, Hosokawa H, Zhuang Z, Brown D, Ausiello DA, Marshansky V
Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.
Am J Physiol Cell Physiol. 2011;300(6):C1442-55 - PMID: 21307348 - PMCID: PMC3118619
Shum WW, Da Silva N, Belleannee C, McKee M, Brown D, Breton S
Regulation of V-ATPase recycling via a RhoA and ROCKII dependent pathway in epididymal clear cells.
Am J Physiol Cell Physiol. 2011;301(1):C31-43 - PMID: 21411727 - PMCID: PMC3129830
Winter C, Kampik NB, Vedovelli L, Rothenberger F, Paunescu TG, Stehberger PA, Brown D, John H, Wagner CA
Aldosterone stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C dependent pathway.
Am J Physiol Cell Physiol. 2011;301(5):C1251-61 - PMID: 21832245 - PMCID: PMC3213922
Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP
An optical platform for cell tracking in adult zebrafish.
Cytometry A. 2011;81(2):176-82 - PMID: 22162445
Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM
Circulating angiogenic cell populations, vascular function, and arterial stiffness.
Atherosclerosis. 2011;220(1):145-50 - PMID: 22093724 - PMCID: PMC3277804
Shon SM, Park JH, Nahrendorf M, Schellingerhout D, Kim JY, Kang BT, Jeong SW, Kim EJ, Ryu JH, Kim K, Kwon IC, Lee DK, Lee MM, Kim DE
Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque.
Atherosclerosis. 2011;216(1):67-73 - PMID: 21334624
Li W, Zhang Y, Bouley R, Chen Y, Matsuzaki T, Nunes P, Hasler U, Brown D, Lu HA
Simvastatin Enhances Aquaporin 2 Surface Expression and Urinary Concentration in Vasopressin Deficient Brattleboro Rats through Modulation of Rho GTPase.
Am J Physiol Renal Physiol. 2011;301(2):F309-18 - PMID: 21511701 - PMCID: PMC3154588
Da Silva N, Cortez-Retamozo V, Reinecker HC, Wildgruber M, Hill E, Brown D, Swirski F, Pittet M, Breton S
A dense network of dendritic cells populates the murine epididymis.
Reproduction. 2011;141(5):653-63 - PMID: 21310816 - PMCID: PMC3657760 - Cover
Shao F, Yuan H, Josephson L, Weissleder R, Hilderbrand SA
Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores.
Dyes Pigm. 2011;90(2):119-122 - PMID: 21475610 - PMCID: PMC3070263
Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP
Angiotensin II Stimulates H-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts.
Cell Physiol Biochem. 2011;28(3):513-20 - PMID: 22116365 - PMCID: PMC3709473
Rigosi E, Frasnelli E, Vinegoni C, Antolini R, Anfora G, Vallortigara G, Haase A
Searching for anatomical correlates of olfactory lateralization in the honeybee antennal lobes: A morphological and behavioural study.
Behav Brain Res.. 2011;221(1):290-4 - PMID: 21402106 - PMCID: PMC3089663
Haase A, Rigosi E, Trona F, Anfora G, Vallortigara G, Antolini R, Vinegoni C
In-vivo two-photon imaging of the honey bee antennal lobe.
Biomed Opt Express. 2011;2(1):131-8 - PMID: 21326643 - PMCID: PMC3028488
Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D
In vivo evaluation of demyelination and remyelination in a nerve crush injury model.
Biomed Opt Express. 2011;2(9):2698-2708 - PMID: 22091449 - PMCID: PMC3184878
Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V
In vivo tomographic imaging of red-shifted fluorescent proteins.
Biomed Opt Express. 2011;2(4):887-900 - PMID: 21483611 - PMCID: PMC3072128
Carney BJ, Shah K
Migration and fate of therapeutic stem cells in different brain disease models.
Neuroscience. 2011;197:37-47 - PMID: 21946010 - PMCID: PMC3589128
Haun JB, Yoon TJ, Lee H, Weissleder R
Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance.
Methods Mol Biol. 2011;726:33-49 - PMID: 21424441
Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R
High-Yielding, Two-Step (18) F Labeling Strategy for (18) F-PARP1 Inhibitors.
ChemMedChem. 2011;6(3):424-7 - PMID: 21360818 - PMCID: PMC3136544
Sun N, Yoon TJ, Lee H, Andress W, Weissleder R, Ham D
Palm NMR and 1-Chip NMR
IEEE J Solid-ST Circ. 2011;46(1):342-352
Goergen CJ, Sosnovik DE
From Molecules to Myofibers: Multiscale Imaging of the Myocardium.
J Cardiovasc Transl Res. 2011;4(4):493-503 - PMID: 21643889 - PMCID: PMC3370890
Gee MS, Nimkin K, Hsu M, Israel EJ, Biller JA, Katz AJ, Mino-Kenudson M, Harisinghani MG
Prospective Evaluation of MR Enterography as the Primary Imaging Modality for Pediatric Crohn Disease Assessment.
AJR Am J Roentgenol. 2011;197(1):224-31 - PMID: 21701034 - PMCID: PMC3711021
Cronin CG, Gervais DA, Hahn PF, Arellano R, Guimaraes AR, Mueller PR
Treatment of Deep Intramuscular and Musculoskeletal Abscess: Experience With 99 CT-Guided Percutaneous Catheter Drainage Procedures.
AJR Am J Roentgenol. 2011;196(5):1182-1188 - PMID: 21512090
Hajjarian Z, Xi J, Jaffer FA, Tearney GJ, Nadkarni SK
Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall.
J Biomed Opt. 2011;16(2):026005 - PMID: 21361689 - PMCID: PMC3056316
Runnels JM*, Carlson AL*, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JMJ, Azab AK, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP
Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy
J Biomed Opt. 2011;16(1):011006 - PMID: 21280893 - PMCID: PMC3033873
Imitola J, Cote D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ
Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice.
J Biomed Opt. 2011;16(2):021109 - PMID: 21361672 - PMCID: PMC3061329
Lin JR, Wang H, Collins AB, Stone JR
Tongue necrosis and systemic vascular amyloidosis.
Hum Pathol. 2011;42(5):734-737 - PMID: 21236468
Laha M, Panizzi P, Nahrendorf M, Bock PE
Engineering streptokinase for generation of active site-labeled plasminogen analogs.
Anal Biochem. 2011;415(2):105-15 - PMID: 21570944 - PMCID: PMC3114107
Gee MS, Harisinghani MG
MRI in patients with inflammatory bowel disease.
J Magn Reson Imaging. 2011;33(3):527-534 - PMID: 21512607 - PMCID: PMC3078716
Shum WW, Ruan YC, Da Silva N, Breton S
Establishment of Cell-Cell Crosstalk in the Epididymis: Control of Luminal Acidification.
J Androl. 2011;32(6):576-86 - PMID: 21441423 - PMCID: PMC3753098
Stone JR, Basso C, Baandrup UT, Bruneval P, Butany J, Gallagher PJ, Halushka MK, Miller DV, Padera RF, Radio SJ, Sheppard MN, Suvarna K, Tan CD, Thiene G, van der Wal AC, Veinot JP
Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology.
Cardiovasc Pathol. 2011;21(1):2-16 - PMID: 21353600
Leone O, Veinot JP, Angelini A, Baandrup UT, Basso C, Berry G, Bruneval P, Burke M, Butany J, Calabrese F, d'Amati G, Edwards WD, Fallon JT, Fishbein MC, Gallagher PJ, Halushka MK, McManus B, Pucci A, Rodriguez ER, Saffitz JE, Sheppard MN, Steenbergen C, Stone JR, Tan C, Thiene G, van der Wal AC, Winters GL
2011 Consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology.
Cardiovasc Pathol. 2011;21(4):245-74 - PMID: 22137237
Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM
Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells.
Leuk Lymphoma. 2011;52(8):1544-55 - PMID: 21699378 - PMCID: PMC4113006
Haase A, Rigosi E, Frasnelli E, Trona F, Tessarolo F, Vinegoni C, Anfora G, Vallortigara G, Antolini R
A multimodal approach for tracing lateralisation along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies.
Eur Biophys J. 2011;40(11):1247-1258 - PMID: 21956452 - PMCID: PMC3366498
Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R
Intraoperative Near-infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury: Reply.
World J Surg. 2011;35(3):694-5 - PMID: 20645091
Baron JM, Higgins JM, Dzik WH
A Revised Timeline for the Origin of Plasmodium falciparum as a Human Pathogen.
J Mol Evol. 2011;73(5-6):297-304 - PMID: 22183792
Coutinho AC, Krishnaraj A, Pires CE, Bittencourt LK, Guimaraes AR
Pelvic applications of diffusion magnetic resonance images.
Magn Reson Imaging Clin N Am. 2011;19(1):133-57 - PMID: 21129639
Berry NC, Sosnovik DE
Cardiomyocyte Death: Insights from Molecular and Microstructural Magnetic Resonance Imaging.
Pediatr Cardiol. 2011;32(3):290-6 - PMID: 21298427 - PMCID: PMC3078825
Malka R, Rom-Kedar V
Bacteria-phagocyte dynamics, axiomatic modelling and mass-action kinetics.
Math Biosci Eng. 2011;8(2):475-502 - PMID: 21631141
Lerner B, Malka R
Investigation of the K2 algorithm in learning Bayesian network classifiers
Appl Artificial Intelligence . 2011;25(1):74-96
Chen HH, Josephson L, Sosnovik DE
Imaging of apoptosis in the heart with nanoparticle technology.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683
Zettergren E, Vickers D, Runnels J, Lin CP, Niedre MJ
Validation of a device for fluorescence sensing of rare circulating cells with diffusive light in an optical flow phantom model.
Conf Proc IEEE Eng Med Biol Soc. 2011;2011:486-9 - PMID: 22254354 - PMCID: PMC3555486
Kamberov YG, Kim J, Mazitschek R, Kuo WP, Whitman M
Microarray profiling reveals the Integrated Stress Response is activated by Halofuginone in mammary epithelial cells.
BMC Res Notes. 2011;4(1):381 - PMID: 21974968 - PMCID: PMC3197508
Thomas S, Waterman P, Chen S, Marinelli B, Seaman M, Rodig S, Ross RW, Josephson L, Weissleder R, Kelly KA
Development of Secreted Protein and Acidic and Rich in Cysteine (SPARC) Targeted Nanoparticles for the Prognostic Molecular Imaging of Metastatic Prostate Cancer
J Nanomedic Nanotechnol. 2011;2(4):112 - PMID: 22319675 - PMCID: PMC3273319
Hucker WJ, Jaffer FA
F-FDG PET Imaging of Atherosclerosis-A New Approach to Detect Inflamed, High-Risk Coronary Plaques?
Curr Cardiovasc Imaging Rep. 2011;4(1):1-3 - PMID: 21297872 - PMCID: PMC3032349
Oei T, Hedgire S, Harisinghani M
Advanced cross-sectional imaging techniques for the detection and characterization of renal masses
Imaging Med. 2011;3 (2):207-218
Bantz KC, Meyer AF, Wittenberg NJ, Im H, Kurtuluş O, Lee SH, Lindquist NC, Oh SH, Haynes CL
Recent progress in SERS biosensing.
Phys Chem Chem Phys. 2011;13(24):11551-67 - PMID: 21509385 - PMCID: PMC3156086
Sabatine MS, Jaffer FA, Staats PN, Stone JR
Case records of the Massachusetts General Hospital. Case 28-2010. A 32-year-old woman, 3 weeks post partum, with substernal chest pain.
New Engl J Med. 2010;363(12):1164-73 - PMID: 20843252
Ng AK, Abramson JS, Digumarthy SR, Reingold JS, Stone JR
Case 24-2010.
New Engl J Med. 2010;363(7):664-675 - PMID: 20818858
Stone JH, Papaliodis GN, Dunbar MR, Stone JR
Case 4-2010 -- a 53-year-old man with arthralgias, oral ulcers, vision loss, and vocal-cord paralysis.
New Engl J Med. 2010;362(6):537-46 - PMID: 20147720
Zhou VW, Goren A, Bernstein BE
Charting histone modifications and the functional organization of mammalian genomes.
Nat Rev Genet. 2010;12(1):7-18 - PMID: 21116306
Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ
Epigenetic memory in induced pluripotent stem cells.
Nature. 2010;467(7313):285-90 - PMID: 20644535 - PMCID: PMC3150836
Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, Echipare L, O'Geen H, Lister R, Pelizzola M, Xi Y, Epstein CB, Bernstein BE, Hawkins RD, Ren B, Chung WY, Gu H, Bock C, Gnirke A, Zhang MQ, Haussler D, Ecker JR, Li W, Farnham PJ, Waterland RA, Meissner A, Marra MA, Hirst M, Milosavljevic A, Costello JF
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.
Nat Biotechnol. 2010;28(10):1097-105 - PMID: 20852635 - PMCID: PMC2955169
Bernstein BE, Stamatoyannopoulos JA, Costello JF, Ren B, Milosavljevic A, Meissner A, Kellis M, Marra MA, Beaudet AL, Ecker JR, Farnham PJ, Hirst M, Lander ES, Mikkelsen TS, Thomson JA
The NIH Roadmap Epigenomics Mapping Consortium.
Nat Biotechnol. 2010;28(10):1045-8 - PMID: 20944595 - PMCID: PMC3607281
Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R
The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1alpha.
Cell. 2010;140(2):280-293 - PMID: 20141841 - PMCID: PMC2821045
Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R
Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection
Nat Nanotechnol. 2010;5(9):660-5 - PMID: 20676091 - PMCID: PMC2934903
Fan Z, Spencer JA, Lu Y, Pitsillides CM, Singh G, Kim P, Yun SH, Toxavidis V, Strom TB, Lin CP, Koulmanda M
In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response.
Nature Med. 2010;16(6):718-22 - PMID: 20495571 - PMCID: PMC2894571
Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE
Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network.
Cell Stem Cell. 2010;6(6):591-602 - PMID: 20569696 - PMCID: PMC2897075
Adli M, Zhu J, Bernstein BE
Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors.
Nat Methods. 2010;7(8):615-8 - PMID: 20622861 - PMCID: PMC2924612
Sakhuja R, Suh WM, Jaffer FA, Jang IK
Residual Thrombogenic Substrate After Rupture of a Lipid-Rich Plaque: Possible Mechanism of Acute Stent Thrombosis?
Circulation. 2010;122(22):2349-2350 - PMID: 21147731
Nahrendorf M, Pittet MJ, Swirski FK
Monocytes: protagonists of infarct inflammation and repair after myocardial infarction.
Circulation. 2010;121(22):2437-45 - PMID: 20530020 - PMCID: PMC2892474
Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M
High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis.
Circulation. 2010;122(17):1707-15 - PMID: 20937980 - PMCID: PMC3003265
Cheng S*, Cohen KS*, Shaw SY*, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ
Association of Colony-Forming Units With Coronary Artery and Abdominal Aortic Calcification.
Circulation. 2010;122(12):1176-1182 - PMID: 20823386 - PMCID: PMC3050056
Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E
Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation.
Eur Heart J. 2010;31(16):1975-84 - PMID: 20601388 - PMCID: PMC2921509
Condeelis J, Weissleder R
In Vivo Imaging in Cancer.
Cold Spring Harb Perspect Biol. 2010;2(12):a003848 - PMID: 20861158 - PMCID: PMC2982169 - Cover
Liong M, Shao H, Haun JB, Lee H, Weissleder R
Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications.
Adv Mater. 2010;22(45):5168-72 - PMID: 20859943 - PMCID: PMC2993874
Ozsolak F, Goren A, Gymrek MA, Guttman M, Regev A, Bernstein BE, Milos PM
Digital transcriptome profiling from attomole-level RNA samples.
Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755
Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M
Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.
J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892
Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R
Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells.
Angew Chem Int Ed Engl. 2010;19 (49):2869-2872 - PMID: 20306505 - PMCID: PMC3433403
Im H, Bantz KC, Lindquist NC, Haynes CL, Oh SH
Vertically oriented sub-10-nm plasmonic nanogap arrays.
Nano Lett. 2010;10(6):2231-6 - PMID: 20499849
Bradner JE, West N, Grachan ML, Greenberg EF, Haggarty SJ, Warnow T, Mazitschek R
Chemical phylogenetics of histone deacetylases.
Nat Chem Biol. 2010;6(3):238-243 - PMID: 20139990 - PMCID: PMC2822059 - Cover
McCarthy JR
Multifunctional agents for concurrent imaging and therapy in cardiovascular disease.
Adv Drug Deliv Rev. 2010;62(11):1023-30 - PMID: 20654664 - PMCID: PMC2974776
Parekkadan B, Upadhyay R, Dunham J, Iwamoto Y, Mizoguchi E, Mizoguchi A, Weissleder R, Yarmush ML
Bone Marrow Stromal Cell Transplants Prevent Experimental Enterocolitis and Require Host CD11b+ Splenocytes.
Gastroenterology. 2010;140(3):966-975.e4 - PMID: 20955701 - PMCID: PMC3033974
Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, Chen S, Vukicevic S, Pietrangelo A, Lin HY, Babitt JL
BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice.
Gastroenterology. 2010;139(5):1721-9 - PMID: 20682319 - PMCID: PMC3295242
Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M
Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice.
J Clin Invest. 2010;120(7):2627-34 - PMID: 20577051 - PMCID: PMC2898607
Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R
Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients.
J Clin Invest. 2010;121(1):442-5 - PMID: 21123946 - PMCID: PMC3007157
Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D
Jarid2 and PRC2, partners in regulating gene expression.
Gene Dev. 2010;24(4):368-80 - PMID: 20123894 - PMCID: PMC2816736
Im H, Lindquist NC, Lesuffleur A, Oh SH
Atomic layer deposition of dielectric overlayers for enhancing the optical properties and chemical stability of plasmonic nanoholes.
ACS Nano. 2010;4(2):947-54 - PMID: 20131870
Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A
Quantitative Nanostructure-Activity Relationship Modeling.
ACS Nano. 2010;4(10):5703-12 - PMID: 20857979 - PMCID: PMC2997621
Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M
Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction.
Circ Res. 2010;107(11):1364-73 - PMID: 20930148 - PMCID: PMC2992104
Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG
Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition.
J Am Chem Soc. 2010;132(23):7838-9 - PMID: 20481508 - PMCID: PMC2892974
Rodriguez E, Nilges M, Weissleder R, Chen JW
Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity.
J Am Chem Soc. 2010;132(1):168-77 - PMID: 19968300 - PMCID: PMC2802665
Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, Deangelo DJ, Carr SA, Schreiber SL, Golub TR, Ebert BL
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.
Proc Natl Acad Sci U S A. 2010;107(28):12617-22 - PMID: 20616024 - PMCID: PMC2906581
Tsigkou O, Pomerantseva I, Spencer JA, Redondo PA, Hart AR, O'Doherty E, Lin Y, Friedrich CC, Daheron L, Lin CP, Sundback CA, Vacanti JP, Neville C
Regenerative Medicine Special Feature: Engineered vascularized bone grafts.
Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421
Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R
Hybrid PET-optical imaging using targeted probes
Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, Churchill M, Weller E, Munshi N, Seehra JS, Weissleder R, Anderson KC, Scadden DT, Raje N
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
Proc Natl Acad Sci U S A. 2010;107(11):5124-9 - PMID: 20194748 - PMCID: PMC2841922
Gao X, Eladari D, Leviel F, Tew BY, Miro-Julia
Deletion of hensin/DMBT1 blocks conversion of {beta}- to {alpha}-intercalated cells and induces distal renal tubular acidosis.
Proc Natl Acad Sci U S A. 2010;107(50):21872-7 - PMID: 21098262 - PMCID: PMC3003085
Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL
Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes.
Proc Natl Acad Sci U S A. 2010;108(2):492-7 - PMID: 21183721 - PMCID: PMC3021060
Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Proc Natl Acad Sci U S A. 2010;107(4):1565-70 - PMID: 20080688 - PMCID: PMC2824379
Higgins JM, Mahadevan L
Physiological and pathological population dynamics of circulating human red blood cells.
Proc Natl Acad Sci U S A. 2010;107(47):20587-92 - PMID: 21059904 - PMCID: PMC2996693
Higgins JM, Sloan SR
Response: Other factors may contribute to differences between sickle cell and non-sickle cell patients.
Blood. 2010;115(21):4315-6 - PMID: 20508172
Xia Y, Babitt JL, Bouley R, Zhang Y, Silva ND, Chen S, Zhuang Z, Samad TA, Brenner GJ, Anderson JL, Hong CC, Schneyer AL, Brown D, Lin HY
Dragon Enhances BMP Signaling and Increases Transepithelial Resistance in Kidney Epithelial Cells.
J Am Soc Nephrol. 2010;21(4):666-77 - PMID: 20167703 - PMCID: PMC2844302
Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D
Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration.
J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035
Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D
Molecular Mechanism of Chemoresistance by Astrocyte Elevated Gene-1.
Cancer Res. 2010;70(8):3249-58 - PMID: 20388796 - PMCID: PMC2855753
Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Aleman JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR
The Phosphoinositide 3-Kinase Regulatory Subunit p85{alpha} Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling.
Cancer Res. 2010;70(13):5305-5315 - PMID: 20530665 - PMCID: PMC3204358
Bagci-Onder T, Wakimoto H, Anderegg M, Cameron C, Shah K
A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell delivered TRAIL in experimental glioma models.
Cancer Res. 2010;71(1):154-63 - PMID: 21084267
Mendenhall EM, Koche RP, Truong T, Zhou VW, Issac B, Chi AS, Ku M, Bernstein BE
GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells.
PLoS Genet. 2010;6(12):e1001244 - PMID: 21170310 - PMCID: PMC3000368
Lo Celso C, Lin CP, Scadden DT
In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow.
Nat Protoc. 2010;6(1):1-14 - PMID: 21212779 - PMCID: PMC3382040
Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E
The absence of a clathrin adapter confers unique polarity essential to proximal tubule function.
Kidney Int. 2010;78(4):382-8 - PMID: 20531453 - PMCID: PMC3684398
Miranda KC, Bond DT, McKee M, Skog J, Paunescu TG, Da Silva N, Brown D, Russo LM
Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease.
Kidney Int. 2010;78(2):191-9 - PMID: 20428099 - PMCID: PMC4451567
McCarthy JR, Korngold E, Weissleder R, Jaffer FA
A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis.
Small. 2010;6(18):2041-9 - PMID: 20721949 - PMCID: PMC3018665
Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K
Determining Multiple Aspects of Stem Cell-Based Therapies Using Novel Diagnostic and Therapeutic Multifunctional Molecules.
Stem Cells. 2010;28(4):832-41 - PMID: 20127797 - PMCID: PMC3021283
Martinez-Boubeta C, Balcells L, Cristool R, Sanfeliu C, Rodriguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martinez B
Self-assembled Multifunctional Fe/MgO Nanospheres for Magnetic Resonance Imaging and Hyperthermia.
Nanomedicine. 2010;6(2):362-370 - PMID: 19800988
Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA
Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction.
Biomaterials . 2010;32(4):1102-9 - PMID: 21035182
van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K
Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors.
Oncogene. 2010;29(22):3185-95 - PMID: 20305695 - PMCID: PMC3390229
Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P
Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma.
Mol Ther. 2010;18(6):1130-42 - PMID: 20179672 - PMCID: PMC2889737
Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ
WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud.
Curr Top Dev Biol. 2010;20(22):1993-2002 - PMID: 21055947 - PMCID: PMC2998074
McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R
Targeted nanoagents for the detection of cancers.
Mol Oncol. 2010;4(6):511-28 - PMID: 20851695 - PMCID: PMC2981649
Pandharipande PV, Gervais DA, Hartman RI, Harisinghani MG, Feldman AS, Mueller PR, Gazelle GS
Renal Mass Biopsy to Guide Treatment Decisions for Small Incidental Renal Tumors: A Cost-effectiveness Analysis.
Radiology. 2010;256(3):836-46 - PMID: 20720070 - PMCID: PMC2923731
Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA
Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis. Novel Detection by Dual-Target Fluorescence Molecular Imaging.
Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475
Yamaura K, Boenisch O, Watanabe T, Ueno T, Vanguri V, Yang J, Tanaka K, Guleria I, Borst J, Zhai Y, Kupiec-Weglinski JW, Najafian N
Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells.
Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922
Jurewicz M, Ueno T, Azzi J, Tanaka K, Murayama T, Yang S, Sayegh MH, Niimi M, Abdi R
Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity.
Am J Transplant. 2010;11(2):348-355 - PMID: 21182586
Osborn EA, Jaffer FA
The year in molecular imaging.
JACC Cardiovasc Imaging. 2010;3(11):1181-95 - PMID: 21071007 - PMCID: PMC3057415
Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R
A Concise Silylamine Approach to 2-Amino-3-hydroxy-indoles with Potent in vivo Antimalaria Activity.
Org Lett. 2010;12(18):3998-4001 - PMID: 20718474
Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H
Self-assembled magnetic filter for highly efficient immunomagnetic separation.
Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961
Kramer CM, Sinusas AJ, Sosnovik DE, French BA, Bengel FM
Multimodality Imaging of Myocardial Injury and Remodeling.
J Nucl Med. 2010;51 Suppl 1:107S-121S - PMID: 20395347 - PMCID: PMC3078824
Libby P, DiCarli M, Weissleder R
The Vascular Biology of Atherosclerosis and Imaging Targets.
J Nucl Med. 2010;51 Suppl 1:33S-37S - PMID: 20395349
Robbins CS, Swirski FK
The multiple roles of monocyte subsets in steady state and inflammation.
Cell Mol Life Sci. 2010;67(16):2685-93 - PMID: 20437077
Emdad L, Sarkar D, Lee SG, Su ZZ, Yoo BK, Dash R, Yacoub A, Fuller CE, Shah K, Dent P, Bruce JN, Fisher PB
Astrocyte elevated gene-1: a novel target for human glioma therapy.
Mol Cancer Ther. 2010;9(1):79-88 - PMID: 20053777 - PMCID: PMC3165052
Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N
TIM-3: a novel regulatory molecule of alloimmune activation.
J Immunol. 2010;185(10):5806-19 - PMID: 20956339 - PMCID: PMC3619947
Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes.
Mol Cell Biol. 2010;31(2):351-64 - PMID: 21059868 - PMCID: PMC3019975
Babitt JL, Lin HY
Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD.
Am J Kidney Dis. 2010;55(4):726-41 - PMID: 20189278 - PMCID: PMC2905036
Gultepe E, Reynoso FJ, Jhaveri A, Kulkarni P, Nagesha D, Ferris C, Harisinghani M, Campbell RB, Sridhar S
Monitoring of magnetic targeting to tumor vasculature through MRI and biodistribution.
Nanomedicine (Lond). 2010;5(8):1173-82 - PMID: 21039195
Stone JR
Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease.
Curr Opin Rheumatol. 2010;23(1):88-94 - PMID: 21037477
Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH
Caveolin-1 Ablation Reduces the Adverse Cardiovascular Effects of N-{omega}-Nitro-L-Arginine Methyl Ester and Angiotensin II.
Endocrinology. 2010;151(3):1236-46 - PMID: 20097717 - PMCID: PMC2840694
Wiles KG, Panizzi P, Kroh HK, Bock PE
Skizzle is a novel plasminogen and plasmin binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation.
J Biol Chem. 2010;285(27):21153-64 - PMID: 20435890 - PMCID: PMC2898333
Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R
Near-Infrared Fluorescent Probe for Imaging of Pancreatic B Cells
Bioconjug Chem. 2010;21:1362-1368 - PMID: 20583828 - PMCID: PMC2912453
Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY
Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles
Bioconjug Chem. 2010;21:14-19 - PMID: 20028085 - PMCID: PMC2902264
Merkulova M, Bakulina A, Thaker YR, Gruber G, Marshansky V
Specific motifs of the V-ATPase a2-subunit isoform interact with catalytic and regulatory domains of ARNO.
Biochim Biophys Acta. 2010;1797(8):1398-1409 - PMID: 20153292
Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T
Imaging Primary Lung Cancers in Mice to Study Radiation Biology.
Int J Radiat Oncol Biol Phys. 2010;76(4):973-977 - PMID: 20206017 - PMCID: PMC2847457
Panchenko MP, Siddiquee Z, Dombkowski DM, Alekseyev YO, Lenburg ME, Walker JD, Macgillivray TE, Preffer FI, Stone JR
Protein Kinase CK1{alpha}LS Promotes Vascular Cell Proliferation and Intimal Hyperplasia.
Am J Pathol. 2010;177(3):1562-72 - PMID: 20696773 - PMCID: PMC2928985
Shi S, Hoogaars WM, de Gorter DJ, van Heiningen SH, Lin HY, Hong CC, Kemaladewi DU, Aartsma-Rus A, Ten Dijke P, 't Hoen PA
BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model.
Neurobiol Dis. 2010;41(2):353-60 - PMID: 20940052 - PMCID: PMC3674857
Setoguchi S, Higgins JM, Mogun H, Mootha VK, Avorn J
Propranolol and the risk of hospitalized myopathy: Translating chemical genomics findings into population-level hypotheses.
Am Heart J. 2010;159(3):428-433 - PMID: 20211305
Miller MA, Barkal L, Jeng K, Herrlich A, Moss M, Griffith LG, Lauffenburger DA
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities.
Integr Biol (Camb). 2010;3(4):422-38 - PMID: 21180771 - PMCID: PMC3173501
Reiner T, Earley S, Turetsky A, Weissleder R
Bioorthogonal Small-Molecule Ligands for PARP1 Imaging in Living Cells.
Chembiochem. 2010;11(17):2374-2377 - PMID: 20967817 - PMCID: PMC3034378
Stone JH, Khosroshahi A, Deshpande V, Stone JR
IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases.
Arthritis Care Res. 2010;62(3):316-22 - PMID: 20391477
Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG
Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models.
PLoS ONE. 2010;5(4):e10032 - PMID: 20386609 - PMCID: PMC2850367
Miranda KC, Karet FE, Brown D
An Extended Nomenclature for Mammalian V-ATPase Subunit Genes and Splice Variants.
PLoS ONE. 2010;5(3):e9531 - PMID: 20224822 - PMCID: PMC2835735
Berny MA, Munnix IC, Auger JM, Schols SE, Cosemans JM, Panizzi P, Bock PE, Watson SP, McCarty OJ, Heemskerk JW
Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear.
PLoS ONE. 2010;5(4):e10415 - PMID: 20454680 - PMCID: PMC2861630
Malka R, Shochat E, Rom-Kedar V
Bistability and bacterial infections.
PLoS ONE. 2010;5(5):e10010 - PMID: 20463954 - PMCID: PMC2864736
Da Silva N, Pisitkun T, Belleannee C, Miller LR, Nelson RD, Knepper MA, Brown D, Breton S
Proteomic analysis of V-ATPase-rich cells harvested from the kidney and epididymis by fluorescence activated cell sorting.
Am J Physiol Cell Physiol. 2010;298(6):C1326-42 - PMID: 20181927 - PMCID: PMC2889637
Belleannee C, Da Silva N, Shum WW, Brown D, Breton S
Role of purinergic signaling pathways in V-ATPase recruitment to the apical membrane of acidifying epididymal clear cells.
Am J Physiol Cell Physiol. 2010;298(4):C817-30 - PMID: 20071692 - PMCID: PMC2853219
Zhuang Z, Marshansky V, Breton S, Brown D
Is caveolin involved in normal proximal tubule (PT) function? Presence in model PT systems but absence in situ.
Am J Physiol Renal Physiol. 2010;300(1):F199-206 - PMID: 20980408 - PMCID: PMC3023221
Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D
Cyclic AMP stimulates apical V-ATPase accumulation, microvillar elongation and proton extrusion in kidney collecting duct A-intercalated cells.
Am J Physiol Renal Physiol. 2010;298(3):F643-54 - PMID: 20053793 - PMCID: PMC2838605
Razansky RN, Rosenthal A, Mallas G, Razansky D, Jaffer FA, Ntziachristos V
Near-infrared fluorescence catheter system for two-dimensional intravascular imaging in vivo.
Opt Express. 2010;18(11):11372-81 - PMID: 20588998
Li C, Pastila RK, Pitsillides C, Runnels JM, Puoris'haag M, Cote D, Lin CP
Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence.
Opt Express. 2010;18(2):988-99 - PMID: 20173920 - PMCID: PMC3369551
Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R
Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography.
Opt Lett. 2010;35(7):1088-90 - PMID: 20364226 - PMCID: PMC2900933
Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN, Reis SA, Klein PS, Mazitschek R, Maglathlin RL, Lewis TA, Haggarty SJ
Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
ACS Med Chem Lett. 2010;2(1):39-42 - PMID: 21874153 - PMCID: PMC3161516
Shah K
In Vivo Imaging of the Dynamics of Different Variants of EGFR in Glioblastomas.
Methods Mol Biol. 2010;680:153-164 - PMID: 21153380
Jaffer FA
Intravital Fluorescence Microscopic Molecular Imaging of Atherosclerosis.
Methods Mol Biol. 2010;680:131-140 - PMID: 21153378 - PMCID: PMC3051165
Shah K
Imaging Fate of Stem Cells at a Cellular Resolution in the Brains of Mice.
Methods Mol Biol. 2010;680:91-101 - PMID: 21153375
Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M
Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells.
Exp Hematol. 2010;38(4):333-9 - PMID: 20167247 - PMCID: PMC3965294
Estiu G, West N, Mazitschek R, Greenberg E, Bradner JE, Wiest O
On the inhibition of histone deacetylase 8.
Bioorg Med Chem. 2010;18(11):4103-4110 - PMID: 20472442 - PMCID: PMC3245874
Gee MS, Kim JY, Gervais DA, Hahn PF, Mueller PR
Management of abdominal and pelvic abscesses that persist despite satisfactory percutaneous drainage catheter placement.
AJR Am J Roentgenol. 2010;194(3):815-20 - PMID: 20173165
Cronin CG, Harisinghani MG, Catalano O, Blake MA
Multitechnique imaging findings of prolene plug hernia repair.
AJR Am J Roentgenol. 2010;195(3):701-6 - PMID: 20729449
Sena BF, Stern JP, Pandharipande PV, Klemm B, Bulman J, Pedrosa I, Rofsky NM
Screening patients to assess renal function before administering gadolinium chelates: assessment of the choyke questionnaire.
AJR Am J Roentgenol. 2010;195(2):424-8 - PMID: 20651199
Uppot RN, Harisinghani MG, Gervais DA
Imaging-guided percutaneous renal biopsy: rationale and approach.
AJR Am J Roentgenol. 2010;194(6):1443-9 - PMID: 20489082
Calfon MA, Vinegoni C, Ntziachristos V, Jaffer FA
Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques.
J Biomed Opt. 2010;15(1):011107 - PMID: 20210433 - PMCID: PMC3188610
Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R
MRI with Magnetic Nanoparticles Monitors Downstream Anti-Angiogenic Effects of mTOR Inhibition.
Mol Imaging Biol. 2010;13(2):314-20 - PMID: 20559742
Thurber GM, Weissleder R
Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels.
Mol Imaging Biol. 2010;13(4):623-32 - PMID: 20809210 - PMCID: PMC3000888
Merkulova M, McKee M, Dip PV, Gruber G, Marshansky V
N-terminal domain of the V-ATPase a2-subunit displays integral membrane protein properties.
Protein Sci. 2010;19(10):1850-1862 - PMID: 20669186 - PMCID: PMC2998721
Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R
Block matching 3D random noise filtering for absorption optical projection tomography.
Phys Med Biol. 2010;55(18):5401-5415 - PMID: 20736500 - PMCID: PMC2934766
Thurber GM, Figueiredo JL, Weissleder R
Detection limits of intraoperative near infrared imaging for tumor resection.
J Surg Oncol. 2010;102(7):758-64 - PMID: 20872807 - PMCID: PMC3758114
Hamilton AM, Rogers KA, Belisle AJ, Ronald JA, Rutt BK, Weissleder R, Boughner DR
Early identification of aortic valve sclerosis using iron oxide enhanced MRI.
J Magn Reson Imaging. 2010;31(1):110-6 - PMID: 20027578 - PMCID: PMC5638659
Islam T, Harisinghani MG
Prostate cancer imaging: what the next decade holds.
Expert Rev Med Devices. 2010;7(5):577-9 - PMID: 20822379
Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH
A novel in vivo regulatory role of P-glycoprotein in alloimmunity.
Biochem Bioph Res Co. 2010;394(3):646-52 - PMID: 20230790 - PMCID: PMC3756468
Shao H, Yoon TJ, Liong M, Weissleder R, Lee H
Magnetic nanoparticles for biomedical NMR-based diagnostics
Beilstein J Nanotechnol. 2010;1:142154 - PMID: 21977404 - PMCID: PMC3045933
Bolondi G, Garuti C, Corradini E, Zoller H, Vogel W, Finkenstedt A, Babitt JL, Lin HY, Pietrangelo A
Altered hepatic BMP signaling pathway in human HFE hemochromatosis.
Blood Cells Mol Dis. 2010;45(4):308-12 - PMID: 20863724 - PMCID: PMC3295241
Figueiredo JL, Siegel C, Nahrendorf M, Weissleder R
Intraoperative Near-Infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury.
World J Surg. 2010;34 (2):336-343 - PMID: 20033407 - PMCID: PMC2809822
Iyer VR, Hahn PF, Blaszkowsky LS, Thayer SP, Halpern EF, Harisinghani MG
Added Value of Selected Images Embedded Into Radiology Reports to Referring Clinicians.
J Am Coll Radiol. 2010;7(3):205-210 - PMID: 20193926 - PMCID: PMC3086392
de la Rosette J, Ahmed H, Barentsz J, Johansen TB, Brausi M, Emberton M, Frauscher F, Greene D, Harisinghani M, Haustermans K, Heidenreich A, Kovacs G, Mason M, Montironi R, Mouraviev V, de Reijke T, Taneja S, Thuroff S, Tombal B, Trachtenberg J, Wijkstra H, Polascik T
Focal therapy in prostate cancer-report from a consensus panel.
J Endourol. 2010;24(5):775-80 - PMID: 20477543
Eisner BH, Kurtz MP, Harisinghani MG
Evolving Role of Magnetic Resonance Imaging in Renal Cancer Imaging.
J Endourol. 2010;24(5):707-11 - PMID: 20433369
Lee DK, Nahrendorf M, Schellingerhout D, Kim DE
Will molecular optical imaging have clinically important roles in stroke management, and how?
J Clin Neurol. 2010;6(1):10-8 - PMID: 20386638 - PMCID: PMC2851295
Prakash P, Kalra MK, Stone JR, Shepard JA, Digumarthy SR
Imaging findings of pericardial metastasis on chest computed tomography.
J Comput Assist Tomogr. 2010;34(4):554-8 - PMID: 20657224
Shenoy-Bhangle A, Nimkin K, Gee MS
Pediatric imaging: Current and emerging techniques.
J Postgrad Med. 2010;56(2):98-102 - PMID: 20622388
Sanghvi D, Harisinghani MG
Modalities in modern radiology: A synopsis.
J Postgrad Med. 2010;56(2):85-7 - PMID: 20622386
Karaosmanoglu AD, Gee MS
Sonographic findings of an adrenal leiomyosarcoma.
J Ultrasound Med. 2010;29(9):1369-73 - PMID: 20733196
Libby P, Nahrendorf M, Weissleder R
Molecular imaging of atherosclerosis: a progress report.
Tex Heart I J. 2010;37(3):324-7 - PMID: 20548813 - PMCID: PMC2879214
Saokar A, Islam T, Jantsch M, Saksena MA, Hahn PF, Harisinghani MG
Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging.
Clin Imaging. 2010;34(5):361-6 - PMID: 20813300
Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG
Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT.
Clin Imaging. 2010;34(1):20-28 - PMID: 20122515
Saokar A, Gee MS, Islam T, Mueller PR, Harisinghani MG
Appearance of primary lymphoid malignancies on lymphotropic nanoparticle-enhanced magnetic resonance imaging using ferumoxtran-10.
Clin Imaging. 2010;34(6):448-52 - PMID: 21092874
Im H, Wittenberg NJ, Lesuffleur A, Lindquist NC, Oh SH
Membrane protein biosensing with plasmonic nanopore arrays and pore-spanning lipid membranes.
Chem Sci. 2010;1(6):688-696 - PMID: 21218136 - PMCID: PMC3015192
McCarthy JR
Nanomedicine and Cardiovascular Disease.
Curr Cardiovasc Imaging Rep. 2010;3(1):42-49 - PMID: 20369034 - PMCID: PMC2848940
Huang S, Sosnovik DE
Molecular and Microstructural Imaging of the Myocardium.
Curr Cardiovasc Imaging Rep. 2010;3(1):26-33 - PMID: 20689659 - PMCID: PMC2916196
Chen HH, Josephson L, Sosnovik DE
Imaging of apoptosis in the heart with nanoparticle technology.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683
Haun JB, Yoon TJ, Lee H, Weissleder R
Magnetic nanoparticle biosensors.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;2(3):291-304 - PMID: 20336708
Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V
Bi-stability of phagocyte-bacteria interaction: when do neutrophils win the battle with Staphylococcus Aureus?
44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy. 2010;:ePub
Kaufman DS, McDougal WS, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 30-2009. A 77-year-old man with recurrent transitional-cell carcinoma of the ureter.
New Engl J Med. 2009;361(13):1292-9 - PMID: 19776411
Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, C
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH
HDAC2 negatively regulates memory formation and synaptic plasticity.
Nature. 2009;459(7243):55-60 - PMID: 19424149 - PMCID: PMC3498958
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.
Nature. 2009;458(7235):223-7 - PMID: 19182780 - PMCID: PMC2754849
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature. 2009;459(7243):103-7 - PMID: 19322176 - PMCID: PMC2761017
Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Nat Genet. 2009;41(4):482-7 - PMID: 19252486 - PMCID: PMC2810136
Chi A, Bernstein B
Developmental biology. Pluripotent chromatin state.
Science. 2009;323(5911):220-1 - PMID: 19131621 - PMCID: PMC4126799
Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J
Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
Science. 2009;326(5950):289-93 - PMID: 19815776 - PMCID: PMC2858594
Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A
Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses.
Science. 2009;326(5950):257-63 - PMID: 19729616 - PMCID: PMC2879337
Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A
Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response.
Science. 2009;324(5932):1334-1338 - PMID: 19498172 - PMCID: PMC2803727
Swirski* FK, Nahrendorf* M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
Science. 2009;325 (5940):612-6 - PMID: 19644120 - PMCID: PMC2803111
Razansky D, Distel M, Vinegoni C, Ma R, Perrimon N, Koster RW, Ntziachristos V
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo
Nat Photonics. 2009;3:412 - 417
Khosroshahi A, Stone JR, Pratt DS, Deshpande V, Stone JH
Painless jaundice with serial multi-organ dysfunction.
Lancet Oncol. 2009;373(9673):1494 - PMID: 19394539
Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.
Nat Methods. 2009;7(1):47-9 - PMID: 19946276 - PMCID: PMC2862482
Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB
Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis.
Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995
Ronald JA*, Chen JW*, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK
Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques.
Circulation. 2009;120(7):592-9 - PMID: 19652086 - PMCID: PMC2736635
Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R
Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease.
Circulation. 2009;119(13):1785-94 - PMID: 19307473 - PMCID: PMC2717745
Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Handschumacher MD, Sullivan S, Johnson B, Titus JS, Iwamoto Y, Wylie-Sears J, Levine RA, Carpentier A
Active Adaptation of the Tethered Mitral Valve. Insights Into a Compensatory Mechanism for Functional Mitral Regurgitation.
Circulation. 2009;120(4):334-42 - PMID: 19597052 - PMCID: PMC2752046
Christen T*, Nahrendorf M*, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P
Molecular Imaging of Innate Immune Cell Function in Transplant Rejection.
Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889
Matter CM, Stuber M, Nahrendorf M
Imaging of the unstable plaque: how far have we got?
Eur Heart J. 2009;30(21):2566-74 - PMID: 19833636 - PMCID: PMC2771148
Jaffer FA
Assessing niacin as an atherosclerosis therapeutic agent valuable insights provided by high-resolution vascular magnetic resonance imaging.
J Am Coll Cardiol. 2009;54(19):1795-6 - PMID: 19874993
Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R
Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition.
Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075
Lee H*, Yoon TJ*, Weissleder R
Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System.
Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069
Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.
Nat Chem Biol. 2009;5(10):734-42 - PMID: 19701185 - PMCID: PMC3032084
Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B, Lin HY, Pietrangelo A, Babitt JL
Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis.
Gastroenterology. 2009;137(4):1489-97 - PMID: 19591830 - PMCID: PMC2757523
Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ
Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.
J Clin Invest. 2009;119(11):3322-8 - PMID: 19809161 - PMCID: PMC2769199
Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA
Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation.
J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134
Shaw SY
Molecular imaging in cardiovascular disease: targets and opportunities.
Nat Rev Cardiol. 2009;6(9):569-79 - PMID: 19621013
Taboada E, Solanas R, Rodriguez E, Weissleder R, Roig A
Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core (&#947;-Fe2O3)/Shell(SiO2) Nanoparticles as High Relaxivity T2-Contrast Agents for Magnetic Resonance Imaging
Adv Funct Mater. 2009;19 :2319-2324
Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA
Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.
Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449
Lee H*, Yoon TJ*, Figueiredo JL, Swirski FK, Weissleder R
Rapid detection and profiling of cancer cells in fine-needle aspirates.
Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371
Yoo B, Gredler R, Vozhilla N, Su Z, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher P, Sarkar D
Identification of genes conferring resistance to 5-fluorouracil.
Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317
Kroh H, Panizzi P, Bock P
Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin.
Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331
Butcher R, Ragains J, Li W, Ruvkun G, Clardy J, Mak H
Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283
Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy.
Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771
Hilderbrand SA, Weissleder R
Near-infrared fluorescence: application to in vivo molecular imaging.
Curr Opin Chem Bio. 2009;14:1-9 - PMID: 19879798
Azab A, Runnels J, Pitsillides C, Moreau A, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson A, Alt C, Burwick N, Roccaro A, Ngo H, Farag M, Melhem M, Sacco A, Munshi N, Hideshima T, Rollins B, Anderson K, Kung A, Lin CP, Ghobrial I
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Blood. 2009;113:4341-51 - PMID: 19139079 - PMCID: PMC2676090
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM
Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma.
Blood. 2009;114(3):619-29 - PMID: 19443661 - PMCID: PMC2713475
Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM
microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922
Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R
Divergent role of donor dendritic cells in rejection versus tolerance of allografts.
J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678
Corradini E, Babitt JL, Lin HY
The RGM/DRAGON family of BMP co-receptors.
Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994
Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD
Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors.
Cancer Res. 2009;69(8):3472-81 - PMID: 19351838 - PMCID: PMC2785462
McCarthy JR
The future of theranostic nanoagents.
Nanomedicine. 2009;4(7):693-5 - PMID: 19839803
Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS
The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells.
Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971
Stone JH, Khosroshahi A, Hilgenberg A, Spooner A, Isselbacher EM, Stone JR
IgG4-related systemic disease and lymphoplasmacytic aortitis.
Arthritis Rheum. 2009;60(10):3139-3145 - PMID: 19790067
Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U
Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
Arthritis Rheum. 2009;60:2314-2324 - PMID: 19644878 - PMCID: PMC3080016
Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R
MRI of a Novel Murine Working Heart Transplant Model
Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535
Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R
Upconverting luminescent nanomaterials: application to in vivo bioimaging.
Chem Commun. 2009;28:4188-90 - PMID: 19585016 - PMCID: PMC2748243
Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L
A DNA-binding Gd chelate for the detection of cell death by MRI.
Chem Commun. 2009;(29):4444-6 - PMID: 19597620 - PMCID: PMC2754278
Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U
Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation.
Radiology. 2009;251(3):813-21 - PMID: 19474377 - PMCID: PMC2687531
Sosnovik DE
Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques?
Radiology. 2009;251:309-10 - PMID: 19401565
Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R
Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors.
Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251
Swirski FK, Weissleder R, Pittet MJ
Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - Cover
Jaffer FA, Libby P, Weissleder R
Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228
Deguchi JO, Yamazaki H, Aikawa E, Aikawa M
Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages.
Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051
Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V
Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model.
Neuroimage. 2009;44(4):1304-11 - PMID: 19041402
McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Neuroimage. 2009;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831
Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O
Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology
Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476
Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819
Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ
Multimodality Cardiovascular Molecular Imaging, Part II
Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054
Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L
Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia.
Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438
Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ
Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium
Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045
Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A
Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure.
Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621
Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ
Diffusion MR tractography of the heart.
J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805
Sosnovik DE, Caravan P
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents
J Cardiovasc Magn Reson. 2009;2:87-94
Im H, Lesuffleur A, Lindquist NC, Oh SH
Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing.
Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634
Koh I, Hong R, Weissleder R, Josephson L
Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions.
Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647
Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J
Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum.
J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731
Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L
The antiproliferative cytostatic effects of a self-activating viridin prodrug.
Mol Cancer Ther. 2009;8(6):1666-1675 - PMID: 19509266 - PMCID: PMC2740925
Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, Garcia-Anoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO
Mutant Sodium Channel for Tumor Therapy.
Mol Cancer Ther. 2009;17(5):810-9 - PMID: 19259066 - PMCID: PMC2751883
Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B
Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1.
Mol Cancer Ther. 2009;18(2):285-94 - PMID: 19844198 - PMCID: PMC2818668
Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton A, Waterman P, Figueiredo JL, Kohler R, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ
Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle
Neoplasia. 2009;11(5):459-468 - PMID: 19412430 - PMCID: PMC2672160 - Cover
Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM
High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model.
ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594
Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ
Implantable diagnostic device for cancer monitoring.
Biosens Bioelectron. 2009;24(11):3252-7 - PMID: 19442510 - PMCID: PMC2738970
Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L
Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation.
J Comb Chem. 2009;12(1):57-64 - PMID: 19928910 - PMCID: PMC2877490
Higgins JM, Eddington DT, Bhatia SN, Mahadevan L
Statistical dynamics of flowing red blood cells by morphological image processing.
PLoS Comput Biol. 2009;5(2):e1000288 - PMID: 19214200 - PMCID: PMC2631282
Piccirillo G M, Binda E, Fiocco R, Vescovi L, Shah K
Brain cancer stem cells.
J Mol Med. 2009;87(11):1087-95 - PMID: 19784875
Brown D, Breton S, Ausiello DA, Marshansky V
Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology.
Traffic. 2009;10(3):275-84 - PMID: 19170982 - PMCID: PMC2896909
Kawada J, Zou P, Mazitschek R, Bradner JE, Cohen JI
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
J Biol Chem. 2009;284(25):17102-9 - PMID: 19386607 - PMCID: PMC2719348
Tharp A, Laha M, Panizzi P, Thompson M, Fuentes-Prior P, Bock P
Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and Kringle 5 of the substrate.
J Biol Chem. 2009;284(29):19511-21 - PMID: 19473980 - PMCID: PMC2740577
Chen S, Reynolds F, Yu L, Weissleder R, Josephson L
A screening paradigm for the design of improved polymer-coated superparamagnetic iron oxide nanoparticles
J Mater Chem. 2009;19:6387-6392
Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L
A Wortmannin-Cetuximab as a Double Drug.
Bioconjug Chem. 2009;20 :2185-2189 - PMID: 19883074 - PMCID: PMC3386608
Devaraj NK*, Keliher EJ*, Thurber GM, Nahrendorf M, Weissleder R
(18)F Labeled Nanoparticles for in Vivo PET-CT Imaging.
Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737
Garanger E, Weissleder R, Josephson L
A Multifunctional Single-Attachment-Point Reagent for Controlled Protein Biotinylation.
Bioconjug Chem. 2009;20(1):170-173 - PMID: 19072220 - PMCID: PMC2692913
McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA
Multimodal Nanoagents for the Detection of Intravascular Thrombi.
Bioconjug Chem. 2009;20(6):1251-5 - PMID: 19456115 - PMCID: PMC2733224
Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF
A colorimetric high throughput screen for the detection of heme crystallization inhibitors.
Antimicrob Agents Chemother. 2009;53(6):2564-8 - PMID: 19307367 - PMCID: PMC2687197
Bhaumik J, Weissleder R, McCarthy JR
Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers.
J Org Chem. 2009;74(16):5894-901 - PMID: 19610602 - PMCID: PMC2888918
Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG
Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer.
Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG
Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223
Kelly K*, Shaw SY*, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R.
Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.
Integr Biol (Camb). 2009;1(4):311-317 - PMID: 20023731 - PMCID: PMC2748356 - Cover
Sales VL, Mettler BA, Engelmayr GC, Aikawa E, Bischoff J, Martin DP, Exarhopoulos A, Moses M, Schoen FJ, Sacks M, Mayer J
Endothelial Progenitor Cells as a Sole Source for Ex vivo Seeding of Tissue-engineered Heart Valves.
Tissue Eng. 2009;16(1):257-67 - PMID: 19698056 - PMCID: PMC2811057
Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer J, Aikawa E
Intravital Molecular Imaging of Small-Diameter Tissue-Engineered Vascular Grafts: A Feasibility Study.
Tissue Eng. 2009;16(4):597-607 - PMID: 19751103
Pittet MJ
Behavior of immune players in the tumor microenvironment.
Curr Opin Oncol. 2009;21(1):53-9 - PMID: 19125019 - PMCID: PMC2901856
Belleannee C, Da Silva N, Shum WW, Marsolais M, Laprade R, Brown D, Breton S
Segmental Expression of the Bradykinin Type 2 Receptor in Rat Efferent Ducts and Epididymis and Its Role in the Regulation of Aquaporin 9.
Biol Reprod. 2009;80(1):134-43 - PMID: 18829705 - PMCID: PMC2804812 - Cover
Comper WD, Russo LM
The glomerular filter: an imperfect barrier is required for perfect renal function.
Curr Opin Nephrol Hy. 2009;18(4):336-42 - PMID: 19474730
Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, Aikawa M
Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II.
Lab Invest. 2009;89(3):315-26 - PMID: 19153555 - PMCID: PMC2932654 - Cover
Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
Gynecol Oncol. 2009;112(3):616-22 - PMID: 19135233 - PMCID: PMC2664404
Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U
Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.
Bone. 2009;44:190-198 - PMID: 19007918 - PMCID: PMC2656637
Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S
The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis.
PLoS ONE. 2009;4(2):e4471 - PMID: 19214237 - PMCID: PMC2637605
Wildgruber M, Lee H, Chudnovskiy A, Yoon T, Etzrodt M, Pittet M, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski F
Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.
PLoS ONE. 2009;4(5):e5663 - PMID: 19461894 - PMCID: PMC2680949
Thurber GM, Figueiredo JL, Weissleder R
Multicolor Fluorescent Intravital Live Microscopy (FILM) for Surgical Tumor Resection in a Mouse Xenograft Model.
PLoS ONE. 2009;4(11):e8053 - PMID: 19956597 - PMCID: PMC2779447
Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S
Systems-level modeling of cancer-fibroblast interaction.
PLoS ONE. 2009;4(9):e6888 - PMID: 19727395 - PMCID: PMC2731225
Bian Y, Sun M, Silver M, Ho KK, Marchionni MA, Caggiano AO, Stone JR, Amende I, Hampton TG, Morgan JP, Yan X
Neuregulin-1 Attenuated Doxorubicin-Induced Decrease in Cardiac Troponins.
Am J Physiol-Heart C. 2009;297(6):H1974-83 - PMID: 19801490 - PMCID: PMC2793128
Van Hoek AN, Bouley R, Lu YX, Silberstein CM, Brown D, Wax MB, Patil RV
Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.
Am J Physiol Renal Physiol. 2009;296(6):F1396-404 - PMID: 19297454 - PMCID: PMC2692439
Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF
Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression.
Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332
McCarthy JR, Bhaumik J, Merbouh N, Weissleder R
High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins.
Org Biomol Chem. 2009;7(17):3430-6 - PMID: 19675897 - PMCID: PMC2749955
Ueno T, Kaneko K, Katano H, Sato Y, Mazitschek R, Tanaka K, Hattori S, Irie S, Sata T, Ogawa-Goto K
Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER.
Exp Cell Res. 2009;316(3):329-40 - PMID: 19932094
Pastor-Soler NM, Fisher JS, Sharpe R, Hill E, Van Hoek A, Brown D, Breton S
Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones.
Reproduction. 2009;139(3):613-21 - PMID: 19948840 - PMCID: PMC3773695
Tsai CC, Vinegoni C, Weissleder R
Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide.
Opt Express. 2009;17(24):21723-31 - PMID: 19997414 - PMCID: PMC2805120
Vinegoni C, Fexon L, Fumene Feruglio P, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R
High throughput transmission optical projection tomography using low cost graphics processing unit
Opt Express. 2009;17(25):22320-22332 - PMID: 20052155 - PMCID: PMC2805020 - Cover
Mansuripur M, Zakharian AR, Lesuffleur A, Oh SH, Jones RJ, Lindquist NC, Im H, Kobyakov A, Moloney JV
Plasmonic nano-structures for optical data storage.
Opt Express. 2009;17(16):14001-14 - PMID: 19654809
Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U
Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects.
Sens Actuat B-Chem. 2009;138(2):591-597 - PMID: 20161242 - PMCID: PMC2706141
Henry F, Cote D, Randolph M, Rust E, Redmond R, Kochevar I, Lin CP, Winograd J
Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy.
Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671
Kumar A, Chung E, Raymond S, van de Water J, Shah K, Fukumura D, Jain R, Bacskai B, Boas D
Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast.
Opt Lett. 2009;34(13):2066-8 - PMID: 19572001 - PMCID: PMC2872111
Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R
Normalized Born ratio for fluorescence optical projection tomography.
Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918
Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R
Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles
Opt Lett. 2009;34(17):2566-8 - PMID: 19724491 - PMCID: PMC2749971
Vonken EJ, Korosoglou G, Yu J, Schar M, Weissleder R, Stuber M
On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA).
Magn Reson Med. 2009;62(2):314-24 - PMID: 19526511 - PMCID: PMC2742771
Brown D, Paunescu TG, Breton S, Marshansky V
Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking.
J Exp Biol. 2009;212(Pt 11):1762-72 - PMID: 19448085 - PMCID: PMC2683016 - Cover
Shum WW, Da Silva N, Brown D, Breton S
Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk.
J Exp Biol. 2009;212(Pt 11):1753-61 - PMID: 19448084 - PMCID: PMC2683015 - Cover
Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS
Genetically engineered T cells to target EGFRvIII expressing glioblastoma.
J Neuro-Oncol. 2009;94(3):373-82 - PMID: 19387557 - PMCID: PMC2730985
Celso CL, Wu JW, Lin CP
In vivo imaging of hematopoietic stem cells and their microenvironment.
J Biophotonics. 2009;2(11):619-631 - PMID: 19847800
Hilderbrand SA
Labels and probes for live cell imaging: overview and selection guide.
Methods Mol Biol. 2009;591:17-45 - PMID: 19957122
Sun N, Liu Y, Lee H, Weissleder R, Ham D
CMOS RF Biosensor Utilizing Nuclear Magnetic Resonance
IEEE J Solid-ST Circ. 2009;44:1629-1643
Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG
Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model.
AJR Am J Roentgenol. 2009;193(3):W230-7 - PMID: 19696264
Baier ND, Hahn PF, Gervais DA, Samir A, Halpern EF, Mueller PR, Harisinghani MG
Fine-needle aspiration biopsy of thyroid nodules: experience in a cohort of 944 patients.
AJR Am J Roentgenol. 2009;193(4):1175-9 - PMID: 19770344
Deliolanis N, Dunham J, Wurdinger T, Figueiredo J, Bakhos T, Ntziachristos V
In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography.
J Biomed Opt. 2009;14(3):030509 - PMID: 19566290 - PMCID: PMC2881930
Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W
Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations.
Arch Pathol Lab Med. 2009;133(12):1949-53 - PMID: 19961250 - PMCID: PMC3694269
Razansky D, Vinegoni C, Ntziachristos V
Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography.
Phys Med Biol. 2009;54:2769-2777 - PMID: 19369709
Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R
Enhancing navigation in biomedical databases by community voting and database-driven text classification.
BMC Bioinformatics. 2009;10(1):317 - PMID: 19799796 - PMCID: PMC2768718
Boland GW, Guimaraes AS, Mueller PR
The evolving radiology landscape: the importance of effective leadership.
Eur J Radiol. 2009;19(10):2321-5 - PMID: 19471944
Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F
Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections.
Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450
Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L
A stabilized demethoxyviridin derivative inhibits PI3 kinase.
Bioorg Med Chem Lett. 2009;19(15):4223-7 - PMID: 19523825 - PMCID: PMC2877487
Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J
Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.
Bioorg Med Chem Lett. 2009;20(1):228-31 - PMID: 19914064
Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J
Antiplasmodial activity of piperazine sulfonamides.
Bioorg Med Chem Lett. 2009;20(1):218-21 - PMID: 19914069
Ueno T, Ikeda T, Ikeda K, Taniuchi H, Suda S, Yeung MY, Matsuno N
HMGB-1 as a Useful Prognostic Biomarker in Sepsis-Induced Organ Failure in Patients Undergoing PMX-DHP.
J Surg Res. 2009;171(1):183-90 - PMID: 20338589
Horner B, Ferguson K, Randolph M, Spencer J, Carlson A, Hirsh E, Lin CP, Butler P
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845
Gee MS, Harisinghani MG, Tabatabaei S
Molecular imaging in urologic surgery.
Urol Clin N Am. 2009;36(2):125-32 - PMID: 19406314
Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R
Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila.
J Vis Exp. 2009;(30):pii:1510 - PMID: 19696720 - PMCID: PMC2736679
Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R
Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging
J Vis Exp. 2009;28:1389 - PMID: 19578329 - PMCID: PMC2794886
Islam T, Josephson L
Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles.
Cancer Biomark. 2009;5(2):99-107 - PMID: 19414927
Islam T, Wolf G
The pharmacokinetics of the lymphotropic nanoparticle MRI contrast agent ferumoxtran-10.
Cancer Biomark. 2009;5(2):69-73 - PMID: 19414923
Harisinghani MG
Nanoparticle enhanced imaging.
Cancer Biomark. 2009;5(2):59 - PMID: 19414921 - Cover
Islam T, Harisinghani MG
Overview of nanoparticle use in cancer imaging.
Cancer Biomark. 2009;5:61-7 - PMID: 19414922
Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M
Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy.
Clin Imaging. 2009;33(4):301-5 - PMID: 19559353
Miller M, Feng X, Li G, Rabitz H
Nonlinear bionetwork structure inference using the random sampling-high dimensional model representation (RS-HDMR) algorithm.
Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6412-5 - PMID: 19964421
Osborn EA, Jaffer FA
The year in molecular imaging.
J Am Coll Cardiol Img. 2009;2:97-113 - PMID: 19356541 - PMCID: PMC4802868
Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R
18F-4V for PET-CT Imaging of VCAM-1 Expression in Atherosclerosis
J Am Coll Cardiol Img. 2009;2:1213-1222 - PMID: 19833312 - PMCID: PMC2773129 - Cover
Lesuffleur A, Lim KS, Lindquist NC, Im H, Warrington AE, Rodriguez M, Oh SH
Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment.
Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1481-4 - PMID: 19963504
Sosnovik DE
Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach
Curr Cardiovasc Imaging Rep. 2009;2:33-39
Sosnovik DE, Caravan P
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents.
Curr Cardiovasc Imaging Rep. 2009;2(2):87-94 - PMID: 20019886 - PMCID: PMC2794433
Shah K
Imaging neural stem cell fate in mouse model of glioma.
Curr Protoc Stem Cell Biol. 2009;Chapter 5:Unit5A.1 - PMID: 19306259
Sosnovik DE
Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach.
Curr Cardiovasc Imaging Rep. 2009;2(1):33-39 - PMID: 20090858 - PMCID: PMC2808047
Razansky D, Vinegoni C, Ntziachristos V
Unprecedented in vivo views at the mesoscopic scale
Biooptics World. 2009;2 (4):22-25
Brass SD, Durand ML, Stone JH, Chen JW, Stone JR
Case records of the Massachusetts General Hospital. Case 36-2008. A 59-year-old man with chronic daily headache.
New Engl J Med. 2008;359(21):2267-78 - PMID: 19020329
Merkel PA, McCarty D, Sharma A, Stone JR
Case records of the Massachusetts General Hospital. Case 31-2008. A 39-year-old man with chest pain, arthralgias, and a mediastinal mass.
New Engl J Med. 2008;359:1603-14 - PMID: 18843125
Weissleder R, Pittet MJ
Imaging in the era of molecular oncology
Nature. 2008;452:580-589 - PMID: 18385732 - PMCID: PMC2708079
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES
Genome-scale DNA methylation maps of pluripotent and differentiated cells.
Nature. 2008;454(7205):766-70 - PMID: 18600261 - PMCID: PMC2896277
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A
Dissecting direct reprogramming through integrative genomic analysis.
Nature. 2008;454(7200):49-55 - PMID: 18509334 - PMCID: PMC2754827
Celso CL, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Cote D, Rowe DW, Lin CP, Scadden DT.
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature. 2008;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276
Ventura A, Young A, Winslow M, Lintault L, Meissner A, Erkeland S, Newman J, Bronson R, Crowley D, Stone J, Jaenisch R, Sharp P, Jacks T
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.
Cell. 2008;132(5):875-86 - PMID: 18329372 - PMCID: PMC2323338
Shum WW, Da Silva N, McKee M, Smith PJ, Brown D, Breton S
Transepithelial Projections from Basal Cells are Luminal Sensors in Pseudostratified Epithelia
Cell. 2008;135:1108-17 - PMID: 19070580 - PMCID: PMC2646085
Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
Nature Med. 2008;14(2):181-7 - PMID: 18193058
Lee H, Sun E, Ham D, Weissleder R
Chip-NMR biosensor for detection and molecular analysis of cells.
Nature Med. 2008;14(8):869-74 - PMID: 18607350 - PMCID: PMC2729055
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, Garcia-Echeverria C, Weissleder R, Mahmood U, Cantley LC, Wong KK
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Nature Med. 2008;14(12)::1351-1356 - PMID: 19029981 - PMCID: PMC2683415
Harisinghani M
Nanoparticle-enhanced MRI: are we there yet?
Lancet Oncol. 2008;9(9):814-815 - PMID: 18760237
Corsten MF, Shah K
Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare.
Lancet Oncol. 2008;9(4):376-84 - PMID: 18374291
Wurdinger T, Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM
miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells.
Cancer Cell. 2008;14(5):382-393 - PMID: 18977327 - PMCID: PMC2597164
Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA
A secreted luciferase for ex vivo monitoring of in vivo processes.
Nat Methods. 2008;5:171-173 - PMID: 18204457 - PMCID: PMC2699561
Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R
Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma.
PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750
Nahrendorf M*, Sosnovik D*, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R
Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury.
Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051
Kircher M, Grimm J, Swirski FK, Libby P, Gerszten R, Allport J, Weissleder R
Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions.
Circulation. 2008;117:388-395 - PMID: 18172031 - PMCID: PMC2705289
Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R
Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis.
Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441
Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik D, Aikawa E, Libby P, Swirski F, Weissleder R.
Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis
Circulation. 2008;117:379-387 - PMID: 18158358 - PMCID: PMC2663426
Libby P, Nahrendorf M, Pittet MJ, Swirski FK
Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal.
Circulation. 2008;117(25):3168-70 - PMID: 18574058
Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne S, Blankesteijn M, Sosnovik D, Jaffer F, Tung CH, Weissleder R
Transglutaminase activity in acute infarcts predicts healing outcome and let ventricular remodelling : implications for FXIII therapy and antithrombin use in myocardial infarction
Eur Heart J. 2008;29:445-454 - PMID: 18276618
Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schar M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M
Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using positive contrast magnetic resonance imaging.
J Am Coll Cardiol. 2008;52:483-91 - PMID: 18672170 - PMCID: PMC2628468
Koh I, Hong R, Weissleder R, Josephson L
Sensitive NMR Sensors Detect Antibodies to Influenza.
Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198
Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ
Conformational cross-talk between alpha(2A)-adrenergic and mu-opioid receptors controls cell signaling.
Nat Chem Biol. 2008;4:126-131 - PMID: 18193048
McCarthy JR, Weissleder R
Multifunctional magnetic nanoparticles for targeted imaging and therapy.
Adv Drug Deliv Rev. 2008;60:1241-1251 - PMID: 18508157 - PMCID: PMC2583936
Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K
Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.
Gastroenterology. 2008;134(4):1028-37 - PMID: 18395084
Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification.
J Clin Invest. 2008;:ePub - PMID: 19005570 - PMCID: PMC2579884
Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ
Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation
J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705
Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, Popoola J, Wang Y, Yagita H, Akiba H, Ansari MJ, Yang J, Turka LA, Rothstein DM, Padera RF, Najafian N, Sayegh MH
The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.
J Clin Invest. 2008;118(2):742-51 - PMID: 18172549 - PMCID: PMC2157561
Pittet MJ, Mempel TR
Regulation of T-cell migration and effector functions: insights from in vivo imaging studies.
Immunol Rev. 2008;221:107-29 - PMID: 18275478
Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG
Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres.
ACS Nano. 2008;2(2):197-202 - PMID: 19206619
Marshansky V, Futai M
The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function.
Curr Opin Cell Biol. 2008;20(4):415-26 - PMID: 18511251
Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R
Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis.
Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693 - PMCID: PMC4044727
Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V
Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo.
Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726
Okazaki M, Ferrandon S, Vilardaga J, Bouxsein M, Potts J, Gardella T
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.
Proc Natl Acad Sci U S A. 2008;105(43):16525-30 - PMID: 18946036 - PMCID: PMC2571912
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Bronson R, Chen J, Weissleder R, Housman D, Charest A.
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene function in gliomagenesis
Proc Natl Acad Sci U S A. 2008;:ePub
Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R
Perturbational profiling of nanomaterial biologic activity.
Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702
Hahn C, Ross K, Warrington I, Mazitschek R, Kanegai C, Wright R, Kung A, Golub T, Stegmaier K
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.
Proc Natl Acad Sci U S A. 2008;105(28):9751-6 - PMID: 18607002 - PMCID: PMC2474517
Breckwoldt M*, Chen JW*, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz M, Weissleder R
Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase
Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors.
Trends Pharmacol Sci. 2008;29(3):159-65 - PMID: 18262662
Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin.
Blood. 2008;111(10):5195-204 - PMID: 18326817 - PMCID: PMC2384142
Higgins JM, Sloan SR
Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders.
Blood. 2008;112(6):2546-53 - PMID: 18535200
Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D
Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy.
J Am Soc Nephrol. 2008;20(3):489-94 - PMID: 19118149 - PMCID: PMC2653682
Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R
Detection of early prostate cancer using a hepsin-targeted imaging agent.
Cancer Res. 2008;68(7):2286-91 - PMID: 18381435 - PMCID: PMC2709884
Ku M, Koche R, Rheinbay E, Mendenhall E, Endoh M, Mikkelsen T, Presser A, Nusbaum C, Xie X, Chi A, Adli M, Kasif S, Ptaszek L, Cowan C, Lander E, Koseki H, Bernstein B
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.
PLoS Genet. 2008;4(10):e1000242 - PMID: 18974828 - PMCID: PMC2567431
Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D
Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines
PLoS Genet. 2008;4(11):e1000287 - PMID: 19043577 - PMCID: PMC2583954
Miller RL, Lucero OM, Riemondy KA, Baumgartner BK, Brown D, Breton S, Nelson RD
The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney.
Kidney Int. 2008;75(4):435-9 - PMID: 19052537 - PMCID: PMC4301582
Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA
Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling.
Kidney Int. 2008;74(12):1557-67 - PMID: 18813286 - PMCID: PMC3730289
Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C
Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review.
Crit Care. 2008;11(2):R47 - PMID: 17448226 - PMCID: PMC2206475
Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK
Regression of drug-resistant lung cancer by the combination of rosiglitazone and Carboplatin.
Clin Cancer Res. 2008;14(20):6478-86 - PMID: 18927287 - PMCID: PMC2696122
Bazzaro M, Lin Z, Santillan A, Lee MK, Wang MC, Chan KC, Bristow RE, Mazitschek R, Bradner J, Roden RB
Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor.
Clin Cancer Res. 2008;14(22):7340-7 - PMID: 19010849 - PMCID: PMC2744414
Hewett J, Nery F, Niland B, Ge P, Tan P, Hadwiger P, Tannous B, Sah D, Breakefield X
siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells.
Hum Mol Genet. 2008;17:1436-45 - PMID: 18258738 - PMCID: PMC2861568
Mendenhall E, Bernstein B
Chromatin state maps: new technologies, new insights.
Curr Opin Genet Dev. 2008;18(2):109-15 - PMID: 18339538 - PMCID: PMC2486450
Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model.
J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321
Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L
Simplified syntheses of complex multifunctional nanomaterials.
Chem Commun. 2008;39:4792-4 - PMID: 18830495 - PMCID: PMC2692914
Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schar M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M
Off-Resonance Angiography: A New Method to Depict Vessels--Phantom and Rabbit Studies.
Radiology. 2008;249(2)::501-509 - PMID: 18780823 - PMCID: PMC2657865
Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U
Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy.
Radiology. 2008;248(3):925-35 - PMID: 18647846 - PMCID: PMC2798096
Lindquist NC, Lesuffleur A, Im H, Oh SH
Sub-micron resolution surface plasmon resonance imaging enabled by nanohole arrays with surrounding Bragg mirrors for enhanced sensitivity and isolation.
Lab Chip. 2008;9(3):382-7 - PMID: 19156286
Sosnovik DE, Nahrendorf M, Weissleder R
Targeted imaging of myocardial damage.
Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275
Nahrendorf M, Sosnovik DE, Weissleder R
MR-optical imaging of cardiovascular molecular targets.
Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635
Sosnovik DE, Nahrendorf M, Weissleder R
Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.
Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271
Groen A, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison T
A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.
J Cell Sci. 2008;121(Pt 14):2293-300 - PMID: 18559893 - PMCID: PMC2902979
Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ
Multimodality Cardiovascular Molecular Imaging, Part I
Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549
Yoshida S, Shimada M, Ueno T, Kitamura Y, Matsuzaki S, Nishikubo S, Nagae M, Nakanishi K, Murata J, Yoshino M
Successful endoscopic submucosal dissection of duodenal cancer.
Endoscopy. 2008;40 Suppl 2:E132-3 - PMID: 18633861
Yoshida S, Shimada M, Ueno T, Yoshino M
Exuberant mucosal granulation by a self-expanding metal stent leading to complete closure of esophageal perforation.
Endoscopy. 2008;40 Suppl 2:E244-5 - PMID: 18991221
Yoshida S, Shimada M, Ueno T, Kato A, Yoshino M
Latex hand glove: a safe and convenient device for the endoscopic removal of foreign bodies.
Endoscopy. 2008;40 Suppl 2:E195-6 - PMID: 18709613
Estiu G, Greenberg E, Harrison C, Kwiatkowski N, Mazitschek R, Bradner J, Wiest O
Structural origin of selectivity in class II-selective histone deacetylase inhibitors.
J Med Chem. 2008;51:2898-906 - PMID: 18412327
Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L
Slow Self-Activation Enhances The Potency of Viridin Prodrugs.
J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427
Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide.
Mol Cancer Ther. 2008;7(11):3575-85 - PMID: 19001440 - PMCID: PMC2748233
Perez JM, Grimm J, Josephson L, Weissleder R
Integrated nanosensors to determine levels and functional activity of human telomerase.
Neoplasia. 2008;10(10):1066-72 - PMID: 18813356 - PMCID: PMC2546593
Grüber G, Marshansky V
New insights into structure-function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0).
Bioessays. 2008;30(11-12):1096-109 - PMID: 18937357
Gabriely G, Wurdinger T, Kesari S, Esau C, Burchard J, Linsley P, Krichevsky A
MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators.
Mol Cell Biol. 2008;28(17):5369-80 - PMID: 18591254 - PMCID: PMC2519720
Law B, Tung CH
Structural modification of protease inducible preprogrammed nanofiber precursor.
Biomacromolecules. 2008;9:421-5 - PMID: 18177006
King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA
E2F3 plays an essential role in cardiac development and function.
Cell Cycle. 2008;7(23):3775-80 - PMID: 19029823 - PMCID: PMC2723769
Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bunemann M
Kinetics of G-protein-coupled receptor signals in intact cells.
Brit J Pharmacol. 2008;153 Suppl 1:S125-32 - PMID: 18193071 - PMCID: PMC2268076
Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski N, Lewis T, Maglathin R, McLean T, Bochkarev A, Plotnikov A, Vedadi M, Arrowsmith C
Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J Biol Chem. 2008;283(17):11355-63 - PMID: 18285338 - PMCID: PMC2431080
Hasler U, Nunes P, Bouley R, Lu HA, Matsuzaki T, Brown D
Acute hypertonicity alters aquaporin-2 trafficking and induces a MAP kinase-dependent accumulation at the plasma membrane of renal epithelial cells.
J Biol Chem. 2008;283(39):26643-61 - PMID: 18664568 - PMCID: PMC2546545
Hilderbrand SA, Kelly KA, Niedre M, Weissleder R
Near Infrared Fluorescence-Based Bacteriophage Particles for Ratiometric pH Imaging.
Bioconjug Chem. 2008;19(8):1635-9 - PMID: 18666791 - PMCID: PMC2705288
Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L
Fate of a Bioactive Fluorescent Wortmannin Derivative in Cells.
Bioconjug Chem. 2008;19:130-137 - PMID: 17988080
Devaraj N, Weissleder R, Hilderbrand S
Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging.
Bioconjug Chem. 2008;19(12):2297-2299 - PMID: 19053305 - PMCID: PMC2677645
Shao F, Weissleder R, Hilderbrand SA
Monofunctional Carbocyanine Dyes for Bio- and Bioorthogonal Conjugation.
Bioconjug Chem. 2008;19(12): :2487-2491 - PMID: 19053316 - PMCID: PMC2656649
Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE
Noninvasive imaging of apoptosis in cardiovascular disease.
Heart Fail Rev. 2008;13(2)::163-173 - PMID: 18074226 - PMCID: PMC2597223
Taktak S, Weissleder R, Josephson L
Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium.
Langmuir. 2008;24 (14):7596-7598 - PMID: 18558729 - PMCID: PMC2748273
Russo LM, Brown D, Lin HY
The soluble transforming growth factor-beta receptor: Advantages and applications.
Int J Biochem Cell B. 2008;41(3):472-6 - PMID: 18339576
Veilleux I, Spencer JA, Biss DP, C
In vivo cell tracking with video rate multimodality laser scanning microscopy
IEEE J Sel Top Quant. 2008;14:10:18
Lasser T, Soubret A, Ripoll J, Ntziachristos V
Surface Reconstruction for free-space 360 degrees fluorescence molecular tomography and the effects of animal motion.
IEEE T Med Imaging. 2008;27(2):188-94 - PMID: 18334440
Brown D, Hasler U, Nunes P, Bouley R, Lu H
Phosphorylation events and the modulation of aquaporin 2 cell surface expression.
Curr Opin Nephrol Hy. 2008;17(5):491-8 - PMID: 18695390 - PMCID: PMC3774073
Yoshida S, Kurokohchi K, Ueno T, Yoshino M, Shimada M, Masaki T
Hepatic von Meyenburg complex: a trigger of severe portal hypertension.
Liver Int. 2008;29(4):614-5 - PMID: 19018981 - PMCID: PMC2711260
Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L
BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
PLoS ONE. 2008;3(12):e3949 - PMID: 19079609 - PMCID: PMC2597248
Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Plough HL, Barrett TA, Weissleder R, Khazaie K
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth.
PLoS ONE. 2008;3:e2916 - PMID: 18698347 - PMCID: PMC2488397
Paunescu TG, Jones AC, Tyszkowski R, Brown D
V-ATPase expression in the mouse olfactory epithelium.
Am J Physiol Cell Physiol. 2008;295(4):C923-30 - PMID: 18667600 - PMCID: PMC2575830
Pastor-Soler NM, Hallows KR, Smolak C, Gong F, Brown D, Breton S
Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells.
Am J Physiol Cell Physiol. 2008;294:C488-94 - PMID: 18160485 - PMCID: PMC4303256
Nunes P, Hasler U, McKee M, Lu HA, Bouley R, Brown D
A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2 (AQP2).
Am J Physiol Cell Physiol. 2008;295(6):C1476-87 - PMID: 18799651 - PMCID: PMC2603565
Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R
A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence.
J Urolology. 2008;179:1610-1614 - PMID: 18295253
Feldman AS, McDougal WS, Harisinghani MG
The potential of nanoparticle-enhanced imaging.
Urol Oncol. 2008;26(1):65-73 - PMID: 18190834
Lu HA, Matsuzaki T, Bouley R, Hasler U, Qin Q, Brown D
The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.
Am J Physiol Renal Physiol. 2008;295(1):F290-4 - PMID: 18434387 - PMCID: PMC2494506
Salthouse C, Hilderbrand S, Weissleder R, Mahmood U
Design and demonstration of a small-animal up-conversion imager.
Opt Express. 2008;16 (26):21731-7 - PMID: 19104605 - PMCID: PMC2717740
Lesuffleur A, Im H, Lindquist NC, Lim KS, Oh SH
Laser-illuminated nanohole arrays for multiplex plasmonic microarray sensing.
Opt Express. 2008;16(1):219-24 - PMID: 18521151
Haller JL, Hyde D, Deliolanis N, de Kleine R, Niedre M, Ntziachristos V
Visualization of Pulmonary Inflammation Using Non-invasive Fluorescence Molecular Imaging.
J Appl Physiol. 2008;104(3):795-802 - PMID: 18202169
Roedl JB, Harisinghani MG, Colen RR, Fischman AJ, Blake MA, Mathisen DJ, Mueller PR
Assessment of treatment response and recurrence in esophageal carcinoma based on tumor length and standardized uptake value on positron emission tomography-computed tomography.
Ann Thorac Surg. 2008;86:1131-8 - PMID: 18805147
Yip S, Shah K
Stem-cell based therapies for brain tumors.
Curr Opin Mol Ther. 2008;10:334-42 - PMID: 18683097
Razansky D, Vinegoni C, Ntziachristos V
Polarization-sensitive optoacoustic tomography of optically diffuse tissues.
Opt Lett. 2008;33(20):2308-10 - PMID: 18923605
Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus W, Ramakrishnan V, Sarkar D, Shah K, Curiel D, Grant S, Fisher P, Dent P
MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors.
Cancer Biol Ther. 2008;7:917-33 - PMID: 18376144
Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel D, Grant S, Fisher P
Searching for a cure: Gene therapy for glioblastoma.
Cancer Biol Ther. 2008;7(9):1335-40 - PMID: 18708757
Hong R, Cima MJ, Weissleder R, Josephson L
Magnetic microparticle aggregation for viscosity determination by MR.
Magn Reson Med. 2008;59:515-520 - PMID: 18306403 - PMCID: PMC2740908
Schmitt M, Potthast A, Sosnovik DE, Polimeni JR, Wiggins GC, Triantafyllou C, Wald LL
A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla.
Magn Reson Med. 2008;59:1431-1439 - PMID: 18506789 - PMCID: PMC2548273
Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP
Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model.
Pancreas. 2008;37(4):440-4 - PMID: 18953259 - PMCID: PMC3806135
Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U
In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe.
Transl Oncol. 2008;1:84-94 - PMID: 18633456 - PMCID: PMC2510813
Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS
Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis.
AJR Am J Roentgenol. 2008;191:1308-19 - PMID: 18941062
Kim P, Puoris'haag M, Cote D, Lin CP, Yun SH
In vivo confocal and multiphoton microendoscopy.
J Biomed Opt. 2008;13(1):010501 - PMID: 18315346 - PMCID: PMC2752311
Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V
Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications.
J Biomed Opt. 2008;13(4):044008 - PMID: 19021336 - PMCID: PMC2749214
Chang K, Jaffer F
Advances in fluorescence imaging of the cardiovascular system.
J Nucl Cardiol. 2008;15(3):417-28 - PMID: 18513648
Brown D
Aquaporins and vasopressin signaling in kidney health and disease: introduction.
Semin Nephrol. 2008;28:215-6 - PMID: 18519082
Bouley R, Hasler U, Lu HA, Nunes P, Brown D
Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus.
Semin Nephrol. 2008;28:266-78 - PMID: 18519087 - PMCID: PMC2494582
Salthouse CD, Weissleder R, Mahmood U
Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis.
IEEE T Biomed Circuits Syst. 2008;2(3):204-211 - PMID: 19830273 - PMCID: PMC2760943
Korosoglou G, Tang L, Kedziorek D, Cosby K, Gilson WD, Vonken EJ, Schar M, Sosnovik D, Kraitchman DL, Weiss RG, Weissleder R, Stuber M
Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON).
J Magn Reson Imaging. 2008;27(5):1175-1180 - PMID: 18425827 - PMCID: PMC2740932
Osborn EA, Jaffer FA
Advances in molecular imaging of atherosclerotic vascular disease.
Curr Opin Cardiol. 2008;23:620-8 - PMID: 18830079 - PMCID: PMC3984946
Boland GW, Guimaraes AS, Mueller PR
The radiologist's conundrum: benefits and costs of increasing CT capacity and utilization.
Eur J Radiol. 2008;19(1):9-11; discussion 12 - PMID: 18766347
Boland GW, Guimaraes AS, Mueller PR
Radiology report turnaround: expectations and solutions.
Eur J Radiol. 2008;18(7):1326-8 - PMID: 18327594
Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG
Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer.
Urology. 2008;71(4):708-12 - PMID: 18295316
Panchenko MP, Silva N, Stone JR
Up-regulation of a hydrogen peroxide-responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia.
Cardiovasc Pathol. 2008;18(3):167-72 - PMID: 18508286 - PMCID: PMC2723736
Collins AB, Smith RN, Stone JR
Classification of amyloid deposits in diagnostic cardiac specimens by immunofluorescence.
Cardiovasc Pathol. 2008;18(4):205-16 - PMID: 18619857
Mazitschek R, Patel V, Wirth D, Clardy J
Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.
Bioorg Med Chem Lett. 2008;18(9):2809-12 - PMID: 18430569 - PMCID: PMC2408937
Xia Z, Huang X, Zhou X, Sun Y, Ntziachristos V, Wong S.
Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation
IEEE T Inf Technol B. 2008;12:569-578
Roedl JB, Blake MA, Holalkere NS, Mueller PR, Colen RR, Harisinghani MG
Lymph node staging in esophageal adenocarcinoma with PET-CT based on a visual analysis and based on metabolic parameters.
Abdom Imaging. 2008;34(5):610-7 - PMID: 18830663
Li CS, Harisinghani MG, Lin WC, Braschi M, Hahn PF, Mueller PR
Enhancement Characteristics of Ultrasmall Superparamagnetic Iron Oxide Particle Within the Prostate Gland in Patients With Primary Prostate Cancer.
J Comput Assist Tomogr. 2008;32:523-528 - PMID: 18664836
Rusanescu G, Weissleder R, Aikawa E
Notch signaling in cardiovascular disease and calcification.
Curr Cardiol Review. 2008;4(3):148-56 - PMID: 19936191 - PMCID: PMC2780816
Sosnovik DE
Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential.
Top Magn Reson Imaging. 2008;19:59-68 - PMID: 18690161 - PMCID: PMC2597277
Miyazaki T,
Biology of Cholesterol Lowering in Atherosclerotic Plaques
Immunol Endocrine and Metabolic Agents. 2008;8(2):105-115
Liu CL, Bernstein BE, Schreiber SL
Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase.
CSH Protoc. 2008;2008:pdb.prot5002 - PMID: 21356834
Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY, Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, Lu Y, Tsai LH
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.
2008;60(5):803-17 - PMID: 19081376 - PMCID: PMC2912147
Salthouse C, Weissleder R, Mahmood U
Development of a Time Domain Fluorimeter (TDF) for Fluorescent Lifetime Multiplexing Analysis
2008;3:204-211
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T
Restoration of p53 function leads to tumour regression in vivo.
Nature. 2007;445:661-5 - PMID: 17251932
Mikkelsen T, Ku M, Jaffe D, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim T, Koche R, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander E, Bernstein B
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
Nature. 2007;448(7153):553-60 - PMID: 17603471 - PMCID: PMC2921165
Bernstein B, Meissner A, Lander E
The mammalian epigenome.
Cell. 2007;128(4):669-81 - PMID: 17320505
Im H, Huang XJ, Gu B, Choi YK
A dielectric-modulated field-effect transistor for biosensing.
Nat Nanotechnol. 2007;2(7):430-4 - PMID: 18654328
Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T
A spatially and temporally restricted mouse model of soft tissue sarcoma.
Nature Med. 2007;13(8):992-997 - PMID: 17676052
Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V
In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography.
Nat Methods. 2007;5(1):45-7 - PMID: 18066071
Aikawa E, Nahrendorf M, Figueiredo JL, Swirski F, Shtatland T, Kohler RH, Jaffer F, Aikawa M, Weissleder R.
Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo.
Circulation. 2007;116(24):2841-50 - PMID: 18040026
Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V
Fluorescence Tomography and Magnetic Resonance Imaging of Myocardial Macrophage Infiltration in Infarcted Myocardium In Vivo.
Circulation. 2007;115:1384-1391 - PMID: 17339546
Sosnovik DE, Nahrendorf M, Weissleder R
Molecular magnetic resonance imaging in cardiovascular medicine.
Circulation. 2007;115(15):2076-86 - PMID: 17438163
Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R
Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor.
Circulation. 2007;115(17):2292-8 - PMID: 17420353
Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R
Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease.
Circulation. 2007;115:377-386 - PMID: 17224478
Jaffer FA, Libby P, Weissleder R
Molecular imaging of cardiovascular disease.
Circulation. 2007;116(9):1052-61 - PMID: 17724271
Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg F, Weissleder R, Carson W, Chiocca A, Kaur B.
Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy
J Natl Cancer I. 2007;(99) 23:1768-1781 - PMID: 18042934
Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D.
Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk
J Exp Med. 2007;204:1911-1922 - PMID: 17646407 - PMCID: PMC2118664
Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517
Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, Hoyng SA, Lin HY, Bloch KD, Peterson RT
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism.
Nat Chem Biol. 2007;4(1):33-41 - PMID: 18026094 - PMCID: PMC2727650
Mahmood U, Wallace MB
Molecular imaging in gastrointestinal disease.
Gastroenterology. 2007;132(1):11-4 - PMID: 17241854
Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance.
J Clin Invest. 2007;117(7):1933-1939 - PMID: 17607365 - PMCID: PMC1904317
Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ
Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata
J Clin Invest. 2007;117(1):195-205 - PMID: 17200719 - PMCID: PMC1716211
Pittet M, Mempel T
Regulation of T Cell Migration and Effector Functions-Insights from in Vivo Imaging Studies
Immunol Rev. 2007;:ePub
Nahrendorf M, Sosnovik D, Waterman P, Swirski F, Pande A, Aikawa E, Figueiredo JL, Pittet M, Weissleder R.
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct
Circ Res. 2007;100:1218-1225 - PMID: 17379832
Pittet M, Grimm J, Berger C, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski F, Weissleder R.
In vivo imaging of T cell delivery to tumors after adoptive transfer therapy
Proc Natl Acad Sci U S A. 2007;104:12457-12461 - PMID: 17640914 - PMCID: PMC1941490
Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K
Mast cells are an essential hematopoietic component for polyp development.
Proc Natl Acad Sci U S A. 2007;104:19977-82 - PMID: 18077429 - PMCID: PMC2148408
Higgins JM, Eddington DT, Bhatia SN, Mahadevan L
Sickle cell vasoocclusion and rescue in a microfluidic device.
Proc Natl Acad Sci U S A. 2007;104(51):20496-500 - PMID: 18077341 - PMCID: PMC2154459
Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Cote D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
Blood. 2007;109:2708-17 - PMID: 17119115 - PMCID: PMC1852222
Leleu X, Jia X, Runnels J, Ngo HT, Moreau AS, Farag M, Spencer JA, Pitsillides CM, Hatjiharissi E, Roccaro A, O'Sullivan G, McMillin DW, Moreno D, Kiziltepe T, Carrasco R, Treon SP, Hideshima T, Anderson KC, Lin CP, Ghobrial IM
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Blood. 2007;110:4417-26 - PMID: 17761832 - PMCID: PMC2234792
Izawa A*, Ueno T*, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R
Importance of donor- and recipient-derived selectins in cardiac allograft rejection.
J Am Soc Nephrol. 2007;18(11):2929-36 - PMID: 17928506
Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K
MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell Delivered S-TRAIL in Human Gliomas.
Cancer Res. 2007;67(19):8994-9000 - PMID: 17908999
Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K.
Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo
Cancer Res. 2007;67 (15):7335-7342 - PMID: 17671203
Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA
Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses.
Cancer Res. 2007;67(19):9398-406 - PMID: 17909049 - PMCID: PMC2850558
Gutierrez O, Lin H
Refractory hyponatremia.
Kidney Int. 2007;71(1):79-82 - PMID: 16985516
Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD
Controversies in nephrology: Response to ''renal albumin handling, facts, and artifacts''
Kidney Int. 2007;72(10):1195-7 - PMID: 17851467
Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD
The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states.
Kidney Int. 2007;71(6):504-13 - PMID: 17228368
Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD
Response to ''Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique''
Kidney Int. 2007;72:1411 - PMID: 18004315
Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD
Response to ''On the origin of albuminuria''
Kidney Int. 2007;72:1409-10 - PMID: 18004312
Russo LM, del Re E, Brown D, Lin HY
Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor.
Diabetes. 2007;56(2):380-8 - PMID: 17259382
McCarthy J, Kelly KA, Sun EY, Weissleder R.
Targeted delivery of multifunctional magnetic nanoparticles
Nanomedicine. 2007;2(2):153-167 - PMID: 17716118
Sosnovik DE, Weissleder R
Emerging concepts in molecular MRI.
Curr Opin Biotech. 2007;18(1):4-10 - PMID: 17126545
Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B
Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis.
Arth Rheum/AR C Res. 2007;56(1):117-128 - PMID: 17195214
Hilderbrand S, Weissleder R.
Optimized pH-responsive cyanine fluorochromes for detection of acidic environments
Chem Commun. 2007;(26):2747-9 - PMID: 17594041
Kim YM, Hilderbrand S, Weissleder R, Tung CH
Sugar sensing based on induced pH changes
Chem Commun. 2007;(22):2299-2301 - PMID: 17534523
Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R.
Tomographic fluorescence imaging of tumor vascular volume in mice.
Radiology. 2007;242 (3):751-758 - PMID: 17325064
Upadhyay R, Sheth RA, Weissleder R, Mahmood U
Quantitative Real-time Catheter-based Fluorescence Molecular Imaging in Mice.
Radiology. 2007;245(2):523-31 - PMID: 17940307
Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U
Colonic Adenocarcinomas: Near-Infrared Microcatheter Imaging of Smart Probes for Early Detection.
Radiology. 2007;244(1):232-8 - PMID: 17507718
Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U
Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment.
Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072
Lacy-Hulbert A*, Ueno T*, Ito T, Jurewicz M, Izawa A, Smith RN, Chase CM, Tanaka K, Fiorina P, Russell PS, Auchincloss H, Sayegh MH, Hynes RO, Abdi R
Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection.
Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - Cover
Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L
Covalent Reactions of Wortmannin under Physiological Conditions.
Chem Biol. 2007;14(3):321-8 - PMID: 17379147
Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P
A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages.
Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040
Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA
A Highly Selective Fluorescent Probe for Thiol Bioimaging.
Org Lett. 2007;10 :37-40 - PMID: 18062694
Kozloff KM, Weissleder R, Mahmood U
Non-Invasive Optical Detection of Bone Mineral.
J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196
Lee H, Liu Y, Ham D, Westervelt RM
Integrated cell manipulation system--CMOS/microfluidic hybrid.
Lab Chip. 2007;7(3):331-7 - PMID: 17330164
Tran AD, Marmo TP, Salam AA, Che S, Finkelstein E, Kabarriti R, Xenias HS, Mazitschek R, Hubbert C, Kawaguchi Y, Sheetz MP, Yao TP, Bulinski JC
HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions.
J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687
Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L
Multiparameter Magnetic Relaxation Switch Assays.
Anal Chem. 2007;(79) 23:8863-9 - PMID: 17983206
Tanaka K, Albin MJ, Yuan X, Yamaura K, Habicht A, Murayama T, Grimm M, Waaga AM, Ueno T, Padera RF, Yagita H, Azuma M, Shin T, Blazar BR, Rothstein DM, Sayegh MH, Najafian N
PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.
J Immunol. 2007;179(8):5204-10 - PMID: 17911605 - PMCID: PMC2291549
Izawa A, Yamaura K, Albin MJ, Jurewicz M, Tanaka K, Clarkson MR, Ueno T, Habicht A, Freeman GJ, Yagita H, Abdi R, Pearson T, Greiner DL, Sayegh MH, Najafian N
A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo.
J Immunol. 2007;179(2):786-96 - PMID: 17617568
Romero P, Zippelius A, Kurth I, Pittet M, Touvrey C, Iancu E, Corthesy P, Devevre E, Speiser D, Rufer N
Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes.
J Immunol. 2007;178(7):4112-9 - PMID: 17371966
Harisinghani M, Ross R, Guimaraes A, Weissleder R
Utility of a New Bolus-Injectable Nanoparticle for Clinical Cancer Staging
Neoplasia. 2007;(9)12:1160-1165 - PMID: 18084623 - PMCID: PMC2134912
Kock N, Kasmieh R, Weissleder R, Shah K
Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL.
Neoplasia. 2007;9(5):435-42 - PMID: 17534449 - PMCID: PMC1877976
Pietrement C, Da Silva N, Silberstein C, James M, Marsolais M, Van Hoek A, Brown D, Pastor-Soler N, Ameen N, Laprade R, Ramesh V, Breton S
Role of NHERF1, CFTR and cAMP in the regulation of aquaporin 9
J Biol Chem. 2007;283:2986-96 - PMID: 18055461
Xia Y, Yu P, Sidis Y, Beppu H, Bloch K, Schneyer A, Lin H
Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.
J Biol Chem. 2007;282(25):18129-40 - PMID: 17472960
Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D
Heat shock protein 70 interacts with aquaporin-2 (AQP2) and regulates its trafficking.
J Biol Chem. 2007;282(39):28721-32 - PMID: 17636261
Lai KS, Ho NH, Cheng JD, Tung CH
Selective Fluorescence Probes for Dipeptidyl Peptidase Activity-Fibroblast Activation Protein and Dipeptidyl Peptidase IV.
Bioconjug Chem. 2007;18(4):1246-50 - PMID: 17489551 - PMCID: PMC2562575
Law B, Weissleder R, Tung CH
Protease-Sensitive Fluorescent Nanofibers.
Bioconjug Chem. 2007;(18) 6 ::1701-1704 - PMID: 17915958 - PMCID: PMC2528070
Kim GY, Josephson L, Langer R, Cima MJ
Magnetic Relaxation Switch Detection of Human Chorionic Gonadotrophin.
Bioconjug Chem. 2007;18(6):2024-8 - PMID: 17892270
Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV
8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
Mol Pharmacol. 2007;72(5):1137-45 - PMID: 17675586
Bogdanov AA, Lin CP, Kang HW
Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody.
Pharmacol Res. 2007;24:1186-92 - PMID: 17373582 - PMCID: PMC2795329
Huang XJ, Ryu SW, Im HS, Choi YK
Wet chemical needlelike assemblies of single-walled carbon nanotubes on a silicon surface.
Langmuir. 2007;23(3):991-4 - PMID: 17241002
Lasser T, Ntziachristos V
Optimization of 360 degrees projection fluorescence molecular tomography.
Med Image Anal. 2007;11(4):389-99 - PMID: 17524701
Hyde D, Miller E, Brooks DH, Ntziachristos V
A statistical approach to inverting the Born ratio.
IEEE T Med Imaging. 2007;26 (7):893-905 - PMID: 17649903
Lesuffleur A, Im H, Lindquist NC, Oh S
Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors
Appl Phys Lett. 2007;90:243110
Smith RN, Ueno T, Ito T, Tanaka K, Shea SP, Abdi R
Chemokines and chronic heart allograft rejection.
Transplantation. 2007;84(3):442-4 - PMID: 17700176
Ansari MJ, Fiorina P, Dada S, Guleria I, Ueno T, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH
Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice.
Clin Immunol. 2007;126(2):140-7 - PMID: 17889619
Ho NH, Weissleder R, Tung CH
A Self-Immolative Reporter For beta-Galactosidase Sensing.
Chembiochem. 2007;8:560-566 - PMID: 17300128
Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R
A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses.
PLoS ONE. 2007;2(10):e1075 - PMID: 17957257 - PMCID: PMC2034600
Kelly KA, Carson J, McCarthy JR, Weissleder R
Novel Peptide Sequence ("IQ-tag") with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging.
PLoS ONE. 2007;2:e665 - PMID: 17653285 - PMCID: PMC1919420
Badr C, Hewett J, Breakefield X, Tannous B
A Highly Sensitive Assay for Monitoring the Secretory Pathway and ER Stress
PLoS ONE. 2007;6:e571
Da Silva N, Shum WW, El-Annan J, Paunescu TG, McKee M, Smith PJ, Brown D, Breton S
Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit.
Am J Physiol Cell Physiol. 2007;293(1):C199-210 - PMID: 17392376 - Cover
Hink M, Shah K, Russinova E, de Vries S, Visser A
Fluorescence Fluctuation Analysis of AtSERK and BRI1 Oligomerization.
Biophys J. 2007;94(3):1052-62 - PMID: 17905839 - PMCID: PMC2186235
Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R
High Resolution Imaging of Murine Myocardial Infarction With Delayed Enhancement Cine Micro-CT.
Am J Physiol-Heart C. 2007;292(6):3172-8 - PMID: 17322414 - PMCID: PMC2680216
Paunescu TG, Russo LM, Da Silva N, Kovacikova J, Mohebbi N, Van Hoek AN, McKee M, Wagner CA, Breton S, Brown D
Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice.
Am J Physiol Renal Physiol. 2007;293(6):F1915-26 - PMID: 17898041
Yi X, Bouley R, Lin HY, Bechoua S, Sun TX, Del Re E, Shioda T, Raychowdhury MK, Lu HA, Abou-Samra AB, Brown D, Ausiello DA
Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.
Am J Physiol Renal Physiol. 2007;292(5):F1303-13 - PMID: 17287200
Paunescu TG, Da Silva N, Russo LM, McKee M, Lu HA, Breton S, Brown D
Association Of Soluble Adenylyl Cyclase (sAC) With The V-ATPase In Renal Epithelial Cells.
Am J Physiol Renal Physiol. 2007;294(1):F130-8 - PMID: 17959750
Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE
Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging.
NMR Biomed. 2007;21(5):453-63 - PMID: 17918777 - PMCID: PMC2629945
Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP
Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam.
Invest Ophth Vis Sci. 2007;48:1782-92 - PMID: 17389512
Sheth RA, Upadhyay R, Weissleder R, Mahmood U
Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems.
Mol Imaging. 2007;6(3):147-55 - PMID: 17532881
Montet-Abou K, Montet X, Weissleder R, Josephson L
Cell internalization of magnetic nanoparticles using transfection agents.
Mol Imaging. 2007;(6) 1:1-9 - PMID: 17311760
Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J
Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography.
Mol Imaging. 2007;6(2):96-107 - PMID: 17445504
Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U
Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging.
Mol Imaging. 2007;6(4):269-76 - PMID: 17711782
Alt C, Veilleux I, Lee H, Pitsillides CM, Cote D, Lin CP
Retinal flow cytometer.
Opt Lett. 2007;32:3450-2 - PMID: 18059963 - PMCID: PMC2794483
Razansky D, Vinegoni C, Ntziachristos V
Multispectral photoacoustic imaging of fluorochromes in small animals.
Opt Lett. 2007;32(19):2891-3 - PMID: 17909608
Deliolanis N, Lasser T, Hyde D, Soubret A, Ripoll J, Ntziachristos V
Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections.
Opt Lett. 2007;32(4):382-4 - PMID: 17356660
Biss DP, Sumorok D, Burns SA, Webb RH, Zhou Y, Bifano TG, Cote D, Veilleux I, Zamiri P, Lin CP
In vivo fluorescent imaging of the mouse retina using adaptive optics.
Opt Lett. 2007;32:659-61 - PMID: 17308593 - PMCID: PMC2808135
McCarthy JR, Weissleder R
Model Systems for Fluorescence and Singlet Oxygen Quenching by Metalloporphyrins.
ChemMedChem. 2007;2:360-365 - PMID: 17245681
Razansky D, Ntziachristos V
Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion.
Med Phys. 2007;34(11):4293-301 - PMID: 18072494
Turner GM, Soubret A, Ntziachristos V
Inversion with early photons.
Med Phys. 2007;34(4):1405-11 - PMID: 17500472
Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I
Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells.
J Biomed Opt. 2007;12:020507 - PMID: 17477705 - PMCID: PMC2798734
Lee H, Alt C, Pitsillides C, Lin CP
Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration.
J Biomed Opt. 2007;12:064034 - PMID: 18163850
Marshansky V
The V-ATPase a2-subunit as a putative endosomal pH-sensor.
Biochem Soc T. 2007;35:1092-9 - PMID: 17956287
Shtatland T, Guettler D, Kossodo M, Pivovarov M, Weissleder R
PepBank - a database of peptides based on sequence text mining and public peptide data sources.
BMC Bioinformatics. 2007;8(1):280 - PMID: 17678535 - PMCID: PMC1976427
Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R
Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm.
J Magn Reson Imaging. 2007;26(2):279-87 - PMID: 17654729
Da Silva N, Shum WW, Breton S
Regulation of vacuolar proton pumping ATPase-dependent luminal acidification in the epididymis.
Asian J Androl. 2007;9(4):476-82 - PMID: 17589784
Hilderbrand SA, Weissleder R
One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes.
Tetrahedron Lett. 2007;48(25):4383-4385 - PMID: 19834587 - PMCID: PMC2761723
Mendelson K, Aikawa E, Mettler B, Sales V, Martin D, Mayer J, Schoen F
Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep.
Cardiovasc Pathol. 2007;16:277-82 - PMID: 17868878
Wei CL, Valvano JW, Feldman MD, Nahrendorf M, Peshock R, Pearce JA
Volume catheter parallel conductance varies between end-systole and end-diastole.
IEEE T Biomed Eng. 2007;54(8):1480-9 - PMID: 17694869
Kim Y, Choi Y, Weissleder R, Tung CH
Membrane permeable esterase-activated fluorescent imaging probe.
Bioorg Med Chem Lett. 2007;17(18):5054-7 - PMID: 17664067 - PMCID: PMC1995663
Johnson J, Swirski F, Gajewska B, Wiley R, Fattouh R, Pacitto S, Wong J, Stampfli M, Jordana M
Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes.
Am J Physiol-Lung C. 2007;293:L730-9 - PMID: 17586699
Faris GW, Ntziachristos V, Rector DM, Wang L
Topics in Biomedical Optics:introduction.
Appl Optics. 2007;46(10):1595-6 - PMID: 17356600
Tan W, Vinegoni C, Norman J, Desai T, Boppart S
Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs.
Microsc Res Techniq. 2007;70(4):361-71 - PMID: 17262787
Nahrendorf M, Weissleder R
Advances in cardiovascular medicine through molecular imaging.
Radiologe. 2007;47(1):18-24 - PMID: 17187263
Grimm J, Kircher MF, Weissleder R
Cell tracking : Principles and applications.
Radiologe. 2007;47(1):25-33 - PMID: 17187264
Lu J, Liong M, Sherman S, Xia T, Kovochich M, Nel AE, Zink JI, Tamanoi F
Mesoporous Silica Nanoparticles for Cancer Therapy: Energy-Dependent Cellular Uptake and Delivery of Paclitaxel to Cancer Cells.
Nanobiotechnology. 2007;3(2):89-95 - PMID: 19936038 - PMCID: PMC2779038
Mahmood U, Upadhyay R
Current and Future Imaging Paradigms in Colorectal Cancer
Seminars in Colon and Rectal Surgery. 2007;18(2):132-138 - PMID: 18516215 - PMCID: PMC2084349
Huang X, Im H, Lee D, Kim H, Choi Y
Ferrocene Functionalized Single-Walled Carbon Nanotube Bundles. Hybrid Interdigitated Construction Film for l-Glutamate Detection
J Phys Chem C. 2007;111(3):1200-1206
Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R
An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles.
Nat Mater. 2006;5(2):118-22 - PMID: 16444262
Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.
Nat Genet. 2006;38(5):531-9 - PMID: 16604073
Bernstein B, Mikkelsen T, Xie X, Kamal M, Huebert D, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber S, Lander E
A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
Cell. 2006;125(2):315-26 - PMID: 16630819
Weissleder R.
Molecular Imaging in Cancer
Science. 2006;312:1168-1171 - PMID: 16728630
Dagia N, Gadhoum S, Knoblauch C, Spencer J, Zamiri P, Lin CP, Sackstein R
G-CSF induces E-selectin ligand expression on human myeloid cells.
Nature Med. 2006;12:1185-90 - PMID: 16980970
Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C
Particularities of the vasculature can promote the organ specificity of autoimmune attack.
Nat Immunol. 2006;7(3):284-92 - PMID: 16444258
Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Janne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
Cancer Cell. 2006;9(6):485-95 - PMID: 16730237
Tannous B*, Grimm J*, Perry K, Chen J, Weissleder R, Breakefield X.
Metabolic Biotinylation of Cell Surface Receptors for in vivo Imaging
Nat Methods. 2006;3(5):391-396 - PMID: 16628210
Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V
V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.
Nat Cell Biol. 2006;8(2):124-36 - PMID: 16415858
Mempel T, Pittet M, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Adrian U.
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation
Immunity. 2006;25(1):129-41 - PMID: 16860762
Nahrendorf M, Hu K, Frantz S, Jaffer F, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlohner S, Novikov M, Dickneite G, Reed G, Jakob P, Rosenzweig A, Bauer W, Weissleder R, Ertl G.
Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice with Myocardial Infarction
Circulation. 2006;113(9):1196-1202 - PMID: 16505171 - PMCID: PMC4066325
Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R
Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis.
Circulation. 2006;114:1504-1511 - PMID: 17000904
Aikawa E, Whittaker P, Farber M, Mendelson K, Padera R, Aikawa M, Schoen F
Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering.
Circulation. 2006;113:1344-52 - PMID: 16534030
Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P
Inflammation in Atherosclerosis. Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo.
Circulation. 2006;114:55-62 - PMID: 16801460
Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE
Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells.
Circulation. 2006;113(19):2301-12 - PMID: 16682613
Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC
Identification of the target self-antigens in reperfusion injury.
J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091
Chakraverty R, Cote D, Buchli J, Cotter P, Hsu R, Zhao G, Sachs T, Pitsillides C, Bronson R, Means T, Lin CP, Sykes M
An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues.
J Exp Med. 2006;203:2021-31 - PMID: 16880259 - PMCID: PMC2118376
Jaffer F, Libby P, Weissleder R.
Molecular and Cellular Imaging of Atherosclerosis, Emerging Applications
J Am Coll Cardiol. 2006;47:1328-1338 - PMID: 16580517
Quinti L, Weissleder R, Tung CH
A Fluorescent Nanosensor for Apoptotic Cells
Nano Lett. 2006;6 (3):488-490 - PMID: 16522048
Vilardaga JP
Switching modes for G protein-coupled receptor activation.
Nat Chem Biol. 2006;2(8):395-6 - PMID: 16850011
Paruchuri S, Yang J, Aikawa E, Melero-Martin J, Khan Z, Loukogeorgakis S, Schoen F, Bischoff J
Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-{beta}2.
Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464
Ntziachristos V
Fluorescence Molecular Imaging.
Annu Rev Biomed Eng. 2006;8:1-33 - PMID: 16834550
Fulci G, Breymann L,Gianni D, Kurozomi K, Rhee S, Yu J, Kaur B, Louis D, Weissleder R, Caligiuri M, Chiocca A.
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA
Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678
Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease.
Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459
Mosley AJ, Meekings KN, McCarthy C, Shepherd D, Cerundolo V, Mazitschek R, Tanaka Y, Taylor GP, Bangham CR
Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection.
Blood. 2006;108(12):3801-7 - PMID: 16912225
Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Desch
Pendrin regulation in mouse kidney primarily is chloride-dependent.
J Am Soc Nephrol. 2006;17(8):2153-63 - PMID: 16825334
Choi YD, Weissleder R, Tung CH.
Selective antitumor effect of novel protease-mediated photodynamic agent
Cancer Res. 2006;66 (14):7225-7229 - PMID: 16849570
Pittet M, Swirski F, Reynolds F, Josephson L, Weissleder R.
Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles
Nat Protoc. 2006;1(1):73-79
McCarthy J, Jaffer F, Weissleder R.
A Macrophage Targeted Theranostic Nanoparticle for Biomedical Applications
Small. 2006;2(8-9):983-987 - PMID: 17193154
Sun EY, Weissleder R, Josephson L.
Continuous Analyte Sensing with Magnetic Nanoswitches
Small. 2006;(2) 10:1144-1147 - PMID: 17193579
Khazaie K, von Boehmer H
The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer.
Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370
Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA
Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging.
Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149
Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D
Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by using Real-time Bioluminescent Imaging.
Radiology. 2006;241(3):822-830 - PMID: 17114629
Chen JW, Querol Sans M, Bogdanov Jr A, Weissleder R
Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates
Radiology. 2006;240 (2):473-81 - PMID: 16864673
Mahmood U
Can a clinically used chemoembolization vehicle improve transgene delivery?
Radiology. 2006;240(3):619-20 - PMID: 16926318
Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN
A robust small-molecule microarray platform for screening cell lysates.
Chem Biol. 2006;13(5):493-504 - PMID: 16720270
Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L.
Multivalent effects of RGD peptides obtained by nanoparticle display
J Med Chem. 2006;49(20):6087-6093
Galande A, Hilderbrand S, Weissleder R, Tung CH.
Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core
J Med Chem. 2006;49(15):4715-20 - PMID: 16854078
Yuan H, Luo J, Weissleder R, Cantley L, Josephson L
Wortmannin-C20 Conjugates Generate Wortmannin.
J Med Chem. 2006;49(2):740-747 - PMID: 16420059
Law B, Quinti L, Choi YD, Weissleder R, Tung CH
A Mitochondrial Targeted Fusion Peptide Exhibits Remarkable Cytotoxicity
Mol Cancer Ther. 2006;5 (8):1944-1949 - PMID: 16928814
Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD
Oligomerization of CXCL10 Is Necessary for Endothelial Cell Presentation and In Vivo Activity.
J Immunol. 2006;177:6991-8 - PMID: 17082614
Alvarez D, Swirski F, Yang T, Fattouh R, Croitoru K, Bramson J, Stampfli M, Jordana M
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
J Immunol. 2006;176(4):2568-80 - PMID: 16456019
Pittet M, Gati A, Le Gal F, Bioley G, Guillaume P, de Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Zippelius A
Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex.
J Immunol. 2006;176:2330-6 - PMID: 16455990
Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palu G, Irimia D, Toner M, Weissleder R, Poznansky MC
Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control.
J Immunol. 2006;176(5):2902-14 - PMID: 16493048
Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L.
Nanoparticle Imaging of Integrins on Tumor Cells
Neoplasia. 2006;8(3):214-222 - PMID: 16611415 - PMCID: PMC1578521
Trehin R, Figueiredo JL, Pittet M, Weissleder R, Josephson L, Mahmood U.
Fluorescent Nanoparticle Uptake for Brain Tumor Visualization
Neoplasia. 2006;8(4):302-311 - PMID: 16756722 - PMCID: PMC1600680
Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL
In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice.
Neoplasia. 2006;8(9):772-80 - PMID: 16984734 - PMCID: PMC1584300
Kelly KA, Waterman P, Weissleder R.
In vivo imaging of molecularly targeted phage
Neoplasia. 2006;8 (12):1011-1018
Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK
N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption.
Mol Cell Biol. 2006;26(11):4185-200 - PMID: 16705170 - PMCID: PMC1489079
Law B, Weissleder R, Tung CH
Peptide-based Biomaterials for Protease-Enhanced Drug Delivery
Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747
Shah K, Breakefield XO
HSV Amplicon Vectors for Cancer Therapy.
Curr Gene Ther. 2006;6(3):361-70 - PMID: 16787187
Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U
Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization.
Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355
Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R
Molecular imaging of myocardial infarction.
J Mol Cell Cardiol. 2006;41:921-933 - PMID: 17067633
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.
RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893
Cabrero JR, Serrador JM, Barreiro O, Mittelbrunn M, Naranjo-Suárez S, Martín-Cófreces N, Vicente-Manzanares M, Mazitschek R, Bradner JE, Avila J, Valenzuela-Fernández A, Sánchez-Madrid F
Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity.
Mol Biol Cell. 2006;17(8):3435-45 - PMID: 16738306 - PMCID: PMC1525231
Banerjee P, Weissleder R, Bogdanov A
Linear Polyethyleneimine Grafted to a Hyperbranched Poly(ethylene glycol)-like Core: A Copolymer for Gene Delivery.
Bioconjug Chem. 2006;17(1):125-31 - PMID: 16417260
Sun EY, Josephson L, Kelly KA, Weissleder R
Development of nanoparticle libraries for biosensing.
Bioconjug Chem. 2006;17(1):109-13 - PMID: 16417258
Montet X, Weissleder R, Josephson L.
Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas
Bioconjug Chem. 2006;17(4):905-911 - PMID: 16848396
Galande A, Weissleder R, Tung CH.
Fluorescence Probe with a pH-Sensitive Trigger
Bioconjug Chem. 2006;17 (2):255-257 - PMID: 16536452
Da Silva N, Pietrement C, Brown D, Breton S
Segmental and cellular expression of aquaporins in the male excurrent duct.
Biochim Biophys Acta. 2006;1758(8):1025-33 - PMID: 16935257
Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R
SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.
J Leukocyte biol. 2006;81(3):748-56 - PMID: 17178915
Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO
Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.
Hum Gene Ther. 2006;17(1):20-30 - PMID: 16409122
Montet X, Yuan H, Weissleder R, Josephson L
Enzyme-based visualization of receptor-ligand binding in tissues.
Lab Invest. 2006;86(5):517-25 - PMID: 16568109
Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA
Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer.
Lab Invest. 2006;86(6):599-609 - PMID: 16607378
Huang X, Li Y, Im H, Yarimaga O, Kim J, Jang D, Cho S, Cai W, Choi Y
Morphology-controlled SWCNT/polymeric microsphere arrays by a wet chemical self-assembly technique and their application for sensors
Nanotechnology. 2006;17(12):2988
Vinegoni C, Ralston T, Tan W, Luo W, Marks DL, Boppart SA
Integrated structural and functional imaging combining spectral-domain optical coherence and multiphoton microscopy
Appl Phys Lett. 2006;88:051105
Nahrendorf M, Weissleder R, Ertl G
Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction?
PLoS ONE. 2006;1:e48 - PMID: 17183677 - PMCID: PMC1762326
Huebert D, Kamal M, O'Donovan A, Bernstein B
Genome-wide analysis of histone modifications by ChIP-on-chip.
Methods. 2006;40(4):365-9 - PMID: 17101450
Nahrendorf M, Streif J, Hiller K, Hu K, Nordbeck P, Ritter O, Sosnovik D, Bauer L, Neubauer S, Jakob P, Ertl G, Spindler M, Bauer W
Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics.
Am J Physiol-Heart C. 2006;290(6):H2516-21 - PMID: 16415075
Breton S, Brown D
New insights into the regulation of V-ATPase-dependent proton secretion.
Am J Physiol Renal Physiol. 2006;292(1):F1-10 - PMID: 17032935
Huang XJ, Im HS, Yarimaga O, Kim JH, Lee DH, Kim HS, Choi YK
Direct electrochemistry of uric acid at chemically assembled carboxylated single-walled carbon nanotubes netlike electrode.
J Phys Chem B. 2006;110(43):21850-6 - PMID: 17064150
Lee H, Alt C, Pitsillides CM, Puoris'haag M, Lin CP
In vivo imaging flow cytometer.
Opt Express. 2006;14:7789-800 - PMID: 19529148 - PMCID: PMC2801598
Bouley R, Hawthorn G, Russo L, Lin H, Ausiello D, Brown D
Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment.
Biol Cell. 2006;98(4):215-32 - PMID: 16563128
Kelly KA, Clemons PA, Yu AM, Weissleder R
High throughput identification of phage-derived imaging agents
Mol Imaging. 2006;5(1):24-30 - PMID: 16779967
Runnels J, Zamiri P, Spencer J, Veilleux I, Wei X, Bogdanov AA, Lin CP
Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy.
Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601
Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V
Normalized transillumination of fluorescent proteins in small animals.
Mol Imaging. 2006;5 (2):153-9 - PMID: 16954030
Hiller K, Waller C, Nahrendorf M, Bauer W, Jakob P
Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging.
Mol Imaging. 2006;5(2):115-21 - PMID: 16954025
Jaffer F, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R
Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials
Mol Imaging. 2006;(5) 2 :85-92 - PMID: 16954022
Sun EY, Josephson L, Weissleder R.
Clickable nanoparticles for targeted imaging
Mol Imaging. 2006;(5) 2:122-128 - PMID: 16954026
Jones G, Marks D, Vinegoni C, Boppart S
High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses.
Opt Lett. 2006;31(10):1543-5 - PMID: 16642166
Xu C, Vinegoni C, Ralston T, Luo W, Tan W, Boppart S
Spectroscopic spectral-domain optical coherence microscopy.
Opt Lett. 2006;31:1079-81 - PMID: 16625909
Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery.
J Neurosurg. 2006;105:445-54 - PMID: 16961141
Choi Y, Weissleder R, Tung CH
Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate.
ChemMedChem. 2006;1:698-701 - PMID: 16902920
Montet X, Rajopadhye M, Weissleder R.
An albumin-activated far-red fluorochrome for in vivo imaging
ChemMedChem. 2006;1(1):66-69 - PMID: 16892337
Choi YD, McCarthy J, Weissleder R, Tung CH
Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy
ChemMedChem. 2006;1(4):458-463 - PMID: 16892381
Ho NH, Weissleder R, Tung CH
Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate.
Bioorg Med Chem. 2006;16:2599-2602 - PMID: 16517162
Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R
Ferumoxtran-10-Enhanced MR Lymphangiography: Does Contrast-Enhanced Imaging Alone Suffice for Accurate Lymph Node Characterization?
AJR Am J Roentgenol. 2006;186(1):144-8 - PMID: 16357394
Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R
Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers.
AJR Am J Roentgenol. 2006;187(6):W582-8 - PMID: 17114509
Hsiao JK, Law B, Weissleder R, Tung CH
In-vivo imaging of tumor associated urokinase-type plasminogen activator activity.
J Biomed Opt. 2006;11(3):34013 - PMID: 16822063
Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA
Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy.
J Biomed Opt. 2006;11(2):21009 - PMID: 16674184
Alt C, Framme C, Schnell S, Lee H, Brinkmann R, Lin CP
Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner.
J Biomed Opt. 2006;10(6):064014 - PMID: 16409079
Niedre MJ, Turner GM, Ntziachristos V
Time-resolved imaging of optical coefficients through murine chest cavities.
J Biomed Opt. 2006;11(6):064017 - PMID: 17212540
Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R
In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging.
Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746
Ho NH, Weissleder R, Tung CH
Development of water-soluble far-red fluorogenic dyes for enzyme sensing
Tetrahedron. 2006;62:578-585
Soubret A, Ntziachristos V
Fluorescence molecular tomography in the presence of background fluorescence.
Phys Med Biol. 2006;51:3983-4001 - PMID: 16885619
Saksena MA, Saokar A, Harisinghani MG
Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging.
Eur J Radiol. 2006;58(3):367-74 - PMID: 16472955
Swirski F, D'Sa A, Kianpour S, Inman M, Stampfli M
Prolonged ovalbumin exposure attenuates airway hyperresponsiveness and T cell function in mice.
Int Arch Allergy Imm. 2006;141(2):130-40 - PMID: 16864992
Ross R, Harisinghani M
New clinical imaging modalities in prostate cancer.
Hematol Oncol Clin N. 2006;20(4):811-30 - PMID: 16861116
Ross R, Harisinghani M
Prostate cancer imaging-what the urologic oncologist needs to know.
Radiol Clin North Am. 2006;44(5):711-22 - PMID: 17030222
Saokar A, Braschi M, Harisinghani M
Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging.
Abdom Imaging. 2006;31(6):660-7 - PMID: 16680506
Weissleder R, Imhof H
Molecular imaging -a new emphasis in radiology
Radiologe. 2006;47(1):6-7 - PMID: 17136404
Huang X, Choi Y, Im H, Yarimaga O, Yoon E, Kim H
Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques
Sensors. 2006;6(7):756–782 - PMCID: PMC3894536
Lerner B, Malka R
Learning Bayesian Networks for Cytogenetic Image Classification
ICPR. 2006;2:772-5
Huang X, Im H, Yarimaga O, Kim J, Jang D, Lee D, Kim H, Choi Y
Electrochemical behavior of needle-like and forest-like single-walled carbon nanotube electrodes
J Electroanal Chem. 2006;594(1):27-34
Deliolanis N, Lasser T, Niedre M, Soubret A, Ntziachristos V
In-vivo Lung Cancer Imaging in Mice using 360 degrees Free-space Fluorescence Molecular Tomography.
2006;1:2370-2372 - PMID: 17946109
Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.
Nature. 2005;435:969-73 - PMID: 15959517 - PMCID: PMC2570168
Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
Nat Genet. 2005;37(7):739-44 - PMID: 15924139 - PMCID: PMC1360984
Ntziachristos V, Ripoll J, Wang L, Weissleder R
Looking and Listening to light: the evolution of whole-body photonic imaging
Nat Biotechnol. 2005;23:313-320 - PMID: 15765087
Weissleder R, Kelly K, Sun E, Shtatland T, Josephson L.
Cell-specific targeting of nanoparticles by multivalent attachment of small molecules
Nat Biotechnol. 2005;23:1418-1423 - PMID: 16244656
Bernstein B, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey D, Huebert D, McMahon S, Karlsson E, Kulbokas E, Gingeras T, Schreiber S, Lander E
Genomic maps and comparative analysis of histone modifications in human and mouse.
Cell. 2005;120(2):169-81 - PMID: 15680324
Jaffer F, Weissleder R
Molecular Imaging in the Clinical Arena
JAMA. 2005;293(7):855-62 - PMID: 15713776
Gounari F, Chang R, Cowan J, Guo Z, Dose M, Gounaris E, Khazaie K.
Loss of adenomatous polyposis coli gene function disrupts thymic development
Nat Immunol. 2005;6(8):800-9 - PMID: 16025118 - PMCID: PMC4662936
Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL.
Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction
Circulation. 2005;111:1800-1805 - PMID: 15809374 - PMCID: PMC3733536
Heller E, Liu E, Tager A, Sinha S, Roberts J, Koehn S, Libby P, Aikawa E, Chen J, Huang P, Freeman M, Moore K, Luster A, Gerszten R
Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.
Circulation. 2005;112:578-86 - PMID: 16043658
Larose E, Yeghiazarians Y, Libby P, Yucel E, Aikawa M, Kacher D, Aikawa E, Kinlay S, Schoen F, Selwyn A, Ganz P
Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging.
Circulation. 2005;112:2324-31 - PMID: 16203910
Deguchi J, Aikawa E, Libby P, Vachon J, Inada M, Krane S, Whittaker P, Aikawa M
Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques.
Circulation. 2005;112:2708-15 - PMID: 16230484
Sutherland F, Perry T, Yu Y, Sherwood M, Rabkin E, Masuda Y, Garcia G, McLellan D, Engelmayr G, Sacks M, Schoen F, Mayer J
From stem cells to viable autologous semilunar heart valve.
Circulation. 2005;111:2783-91 - PMID: 15927990
McCarthy JR, Perez JM, Brueckner C, Weissleder R
Polymeric Nanoparticle Preparation that Eradicates Tumors.
Nano Lett. 2005;5:2552-6 - PMID: 16351214
Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D.
Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes
J Clin Invest. 2005;115(9):2454-2461 - PMID: 16110329 - PMCID: PMC1187933
Shah K, Bureau E, Kim DE, Yang K, Tang Y, Weissleder R, Breakefield XO.
Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression
Ann Neurol. 2005;57(1):34-41 - PMID: 15622535
Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R.
Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle
Circ Res. 2005;96(3):327-36 - PMID: 15653572
Grimm J, Kirsch DG, Windsor SD, Kim CF, Santiago PM, Ntziachristos V, Jacks T, Weissleder R.
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer
Proc Natl Acad Sci U S A. 2005;102(40):14404-14409 - PMID: 16183744 - PMCID: PMC1242291
Evans C, Potma E, Puoris'haag M, C
Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.
Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840
Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP
The B1-subunit of the H(+) ATPase is required for maximal urinary acidification.
Proc Natl Acad Sci U S A. 2005;102(38):13616-21 - PMID: 16174750 - PMCID: PMC1224669
Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K.
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-{beta} signals in vivo
Proc Natl Acad Sci U S A. 2005;102(2):419-24 - PMID: 15623559 - PMCID: PMC544311
Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V.
Volumetric tomography of fluorescent proteins through small animals in vivo
Proc Natl Acad Sci U S A. 2005;102:18252-18257 - PMID: 16344470 - PMCID: PMC1317905
Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA Jr.
Detection of Early Antiangiogenic Effects in Human Colon Adenocarcinoma Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor
Cancer Res. 2005;65(20):9253-60 - PMID: 16230386
Montet X, Ntziachristos V, Grimm J, Weissleder R.
Tomographic Fluorescence Mapping of Tumor Targets
Cancer Res. 2005;65 (14):6330-6336 - PMID: 16024635
Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R.
In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging
Cancer Res. 2005;65(18):8324-30 - PMID: 16166309
Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O
The progress and promise of molecular imaging probes in oncologic drug development.
Clin Cancer Res. 2005;11(22):7967-85 - PMID: 16299226
Engelmayr G, Rabkin E, Sutherland F, Schoen F, Mayer J, Sacks M
The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue.
Biomaterials . 2005;26:175-87 - PMID: 15207464
Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO.
Codon-optimized gaussia luciferase cDNA for Mammalian gene expression in culture and in vivo
Mol Ther. 2005;11(3):435-43 - PMID: 15727940
Shah K, Tung CH, Breakefield X, Weissleder R.
In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis
Mol Ther. 2005;11 (6):926-931 - PMID: 15922963
Basilion JP, Yeon S, Botnar R
Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality.
Curr Top Dev Biol. 2005;70(c):1-33 - PMID: 16338335
Mahmood U, Josephson L
Molecular MR Imaging Probes
P IEEE. 2005;93 (4):800-808
Figueiredo JL, Alencar H, Weissleder R, Mahmood U
Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer.
Int J Cancer. 2005;118(11):2672-7 - PMID: 16380983
Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U.
A novel mouse model for segmental orthotopic colon cancer
Int J Cancer. 2005;117(3):335-9 - PMID: 15900588
Querol M, Chen JW, Weissleder R, Bogdanov A Jr.
DTPA-bisamide-Based MR Sensor Agents for Peroxidase Imaging
Org Lett. 2005;7(9):1719-22 - PMID: 15844889
Nahrendorf M, Spindler M, Hu K, Bauer L, Ritter O, Nordbeck P, Quaschning T, Hiller K, Wallis J, Ertl G, Bauer W, Neubauer S
Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction.
Cardiovasc Res. 2005;65(2):419-27 - PMID: 15639481
Pelzer T, Jazbutyte V, Hu K, Segerer S, Nahrendorf M, Nordbeck P, Bonz AW, Muck J, Fritzemeier KH, Hegele-Hartung C, Ertl G, Neyses L
The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats.
Cardiovasc Res. 2005;67(4):604-12 - PMID: 15950203
Tsourkas A, Newton G, Perez JM, Basilion J, Weissleder R.
Detection of Peroxidase-Mediated Dityrosine Formation with Enhanced Yellow Fluorescent Protein
Anal Chem. 2005;77:2862-2867 - PMID: 15859603
Framme C, Alt C, Schnell S, Brinkmann R, Lin CP
[Selective RPE laser treatment with a scanned cw laser beam in rabbits]
Ophthalmologie. 2005;102(5):491-6 - PMID: 15883846
Gajewska B, Tafuri A, Swirski F, Walker T, Johnson J, Shea T, Shahinian A, Goncharova S, Mak T, Stampfli M, Jordana M
B7RP-1 is not required for the generation of Th2 responses in a model of allergic airway inflammation but is essential for the induction of inhalation tolerance.
J Immunol. 2005;174(5):3000-5 - PMID: 15728513
Ito T*, Ueno T*, Clarkson MR, Yuan X, Jurewicz MM, Yagita H, Azuma M, Sharpe AH, Auchincloss H, Sayegh MH, Najafian N
Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo.
J Immunol. 2005;174(11):6648-56 - PMID: 15905503
Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L.
Nanoparticles for the Optical Imaging of Tumor E-selectin
Neoplasia. 2005;7(10):904-11 - PMID: 16242073
Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R
Novel Multiwavelength Microscopic Scanner for Mouse Imaging.
Neoplasia. 2005;7(11):977-983 - PMID: 16331883 - PMCID: PMC1502018
Sato F, Fukuhara H, Basilion JP
Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo.
Neoplasia. 2005;7(9):838-46 - PMID: 16229806 - PMCID: PMC1501932
Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A Jr.
Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model
Neoplasia. 2005;7(9):847-53 - PMID: 16229807 - PMCID: PMC1351316
Shinde Patil VR, Friedrich EB, Wolley AE, Gerszten RE, Allport JR, Weissleder R.
Bone Marrow-Derived lin(-)c-kit(+)Sca-1(+) Stem Cells Do Not Contribute to Vasculogenesis in Lewis Lung Carcinoma
Neoplasia. 2005;7(3):234-40 - PMID: 15799823 - PMCID: PMC1501134
Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R.
Optical Imaging of Spontaneous Breast Tumors Using Protease Sensing
Invest Radiol. 2005;(6):321-327 - PMID: 15905717
Kim DE, Jaffer FA, Weissleder R, Tung CH, Schellingerhout D.
Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis
J Cereb Blood Flow Metab. 2005;25(2):226-33 - PMID: 15678125
Galande A, Weissleder R, Tung CH.
An Effective Method of On-Resin Disulfide Bond Formation in Peptides
J Comb Chem. 2005;7:174-177 - PMID: 15762743
Xia Y, Sidis Y, Mukherjee A, Samad TA, Brenner G, Woolf CJ, Lin HY, Schneyer A
Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis.
Endocrinology. 2005;146(8):3614-21 - PMID: 15890774 - PMCID: PMC1351303
Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ
DRAGON, a bone morphogenetic protein co-receptor.
J Biol Chem. 2005;280(14):14122-9 - PMID: 15671031
Babitt J, Zhang Y, Samad T, Xia Y, Tang J, Campagna J, Schneyer A, Woolf C, Lin HY
Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.
J Biol Chem. 2005;280(33):29820-7 - PMID: 15975920
Beaulieu V, Da Silva N, Pastor-Soler N, Brown CR, Smith PJ, Brown D, Breton S
Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling.
J Biol Chem. 2005;280(9):8452-63 - PMID: 15591047
Hilderbrand S, Lippard S
Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity.
Inorg Chem. 2005;43:4674-82 - PMID: 15257596
Hilderbrand SA, Kelly KA, Weissleder R, Tung CH.
Monofunctional near-infrared fluorochromes for imaging applications
Bioconjug Chem. 2005;16(5):1275-81 - PMID: 16173808
Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R.
In Vivo Imaging of Activated Endothelium Using an Anti-VCAM-1 Magneto optical Probe
Bioconjug Chem. 2005;(3):576-581 - PMID: 15898724
Reynolds F, Weissleder R, Josephson L.
Protamine as an efficient membrane-translocating Peptide
Bioconjug Chem. 2005;16(5):1240-5 - PMID: 16173804
Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L.
Synthesis and Activity of C11-Modified Wortmannin Probes for P13 Kinase
Bioconjug Chem. 2005;(3):669-675 - PMID: 15898736
Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R.
Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy
Int J Radiat Oncol Biol Phys. 2005;63(4):1262-9 - PMID: 16253781
Tung CH, Quinti L, Jaffer F, Weissleder R
A Branched Fluorescent Peptide Probe for Imaging of Activated Platelets
Mol Pharmacol. 2005;2:92-95 - PMID: 15804182
Chen WT, Mahmood U, Weissleder R, Tung CH
Arthritis imaging using a near-infrared fluorescence folate-targeted probe
Arthritis Res Ther. 2005;7:R310-R317 - PMID: 15743478 - PMCID: PMC1065321
Da Silva N, Silberstein C, Beaulieu V, Pietrement C, Van Hoek AN, Brown D, Breton S
Postnatal expression of aquaporins in epithelial cells of the rat epididymis.
Biol Reprod. 2005;74(2):427-38 - PMID: 16221990
Pietrement C, Sun-Wada GH, Silva ND, McKee M, Marshansky V, Brown D, Futai M, Breton S
Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis.
Biol Reprod. 2005;74(1):185-94 - PMID: 16192400
Zacharakis G, Ripoll J, Weissleder R, Ntziachristos V.
Fluorescent protein tomography scanner for small animal imaging
IEEE T Med Imaging. 2005;24(7):878-85 - PMID: 16011317
Soubret A, Ripoll J, Ntziachristos V.
Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio
IEEE T Med Imaging. 2005;24(10):1377-86 - PMID: 16229423
Marias K, Ripoll J, Meyer H, Ntziachristos V, Orphanoudakis S.
Image analysis for assessing molecular activity changes in time-dependent geometries
IEEE T Med Imaging. 2005;24(7):894-900 - PMID: 16011319
Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X
Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery.
Hum Gene Ther. 2005;16:1367-76 - PMID: 16390268
Sabolic I, Herak-Kramberger CM, Antolovic R, Breton S, Brown D
Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin.
Toxicology. 2005;218(2-3):149-63 - PMID: 16288946
Shah K, Weissleder R
Molecular Optical Imaging: Applications Leading to the Development of Present Day Therapeutics
NeuroRx. 2005;2:215-225 - PMID: 15897946 - PMCID: PMC1064987
Law B, Weissleder R, Tung CH.
Mechanism-Based Fluorescent Reporter for Protein Kinase A Detection
Chembiochem. 2005;6(8):1361-1367 - PMID: 16010698
Koch AM, Reynolds F, Merkle HP, Weissleder R, Josephson L.
Transport Of Surface-Modified Nanoparticles Through Cell Monolayers
Chembiochem. 2005;6(2):337-345 - PMID: 15651046
Bouley R, Lin HY, Raychowdhury MK, Marshansky V, Brown D, Ausiello DA
Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway.
Am J Physiol Cell Physiol. 2005;288(6):C1390-401 - PMID: 15677378
Miller RL, Zhang P, Smith M, Beaulieu V, Paunescu TG, Brown D, Breton S, Nelson RD
V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice.
Am J Physiol Cell Physiol. 2005;288(5):C1134-44 - PMID: 15634743
Lisi S, Botta R, Pinchera A, Collins AB, Refetoff S, Arvan P, Bu G, Grasso L, Marshansky V, Bechoua S, Hurtado-Lorenzo A, Marcocci C, Brown D, McCluskey RT, Marinò M
Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice.
Am J Physiol Cell Physiol. 2005;290(4):C1160-7 - PMID: 16306127
Reynolds F, O'loughlin T, Weissleder R, Josephson L.
Method of Determining Nanoparticle Core Weight
Anal Bioanal Chem. 2005;77(3):814-817 - PMID: 15679348
Bouley R, Pastor-Soler N, Cohen O, McLaughlin M, Breton S, Brown D
Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra).
Am J Physiol Renal Physiol. 2005;288(6):F1103-12 - PMID: 15644488
Mazitschek R, Huwe A, Giannis A
Synthesis and biological evaluation of novel fumagillin and ovalicin analogues.
Org Biomol Chem. 2005;3(11):2150-4 - PMID: 15917904
Montes M, Rufer N, Appay V, Reynard S, Pittet M, Speiser D, Guillaume P, Cerottini J, Romero P, Leyvraz S
Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy.
Clin Exp Immunol. 2005;142:292-302 - PMID: 16232216 - PMCID: PMC1809512
Chen WT, Khazaie K, Zhang G, Weissleder R, Tung CH
Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe
Mol Imaging. 2005;4 (1):67-74 - PMID: 15912902
Gillies R, Hoffman J, Lam K, Menkens A, Piwnica-Worms D, Sullivan D, Weissleder R.
Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents
Mol Imaging. 2005;4:1-6
Wunder A, Schellenberger E, Mahmood U, Bogdanov A Jr, Muller-Ladner U, Weissleder R, Josephson L.
Methotrexate-induced accumulation of fluorescent annexin v in collagen-induced arthritis
Mol Imaging. 2005;4(1):1-6 - PMID: 15967121
Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R
MIPortal: A High Capacity Server for Molecular Imaging Research.
Mol Imaging. 2005;4(4):425-31 - PMID: 16285904
Montet-Abou K, Montet X, Weissleder R, Josephson L.
Transfection agent induced nanoparticle cell loading
Mol Imaging. 2005;4(3):165-71 - PMID: 16194448
Wei X, Sipkins D, Pitsillides C, Novak J, Georgakoudi I, Lin C
Real-time detection of circulating apoptotic cells by in vivo flow cytometry.
Mol Imaging. 2005;4:415-6 - PMID: 16285902 - PMCID: PMC2801924
Turner GM, Zacharakis G, Soubret A, Ripoll J, Ntziachristos V.
Complete-angle projection diffuse optical tomography by use of early photons
Opt Lett. 2005;30(4):409-11 - PMID: 15762444
Shah K.
Current Advances in Molecular Imaging of Gene and Cell Therapy for Cancer
Cancer Biol Ther. 2005;4(5):518-523 - PMID: 15908803
Streif J, Nahrendorf M, Hiller K, Waller C, Wiesmann F, Rommel E, Haase A, Bauer W
In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging.
Magn Reson Med. 2005;53(3):584-92 - PMID: 15723416
Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L.
Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle
Magn Reson Med. 2005;54(3):718-724 - PMID: 16086367
Achilefu S, Contag CH, Savitsky AP, Weissleder R
Chemical and Genetic Sensors in Biomedical Research.
J Biomed Opt. 2005;10(4):41201 - PMID: 23171967
Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V.
Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography
J Biomed Opt. 2005;10(4):44019 - PMID: 16178652
Ntziachristos V, Turner G, Dunham J, Windsor S, Soubret A, Ripoll J, Shih HA
Planar fluorescence imaging using normalized data.
J Biomed Opt. 2005;10(6):64007 - PMID: 16409072
Querol Sans M*, Chen JW*, Weissleder R, Bogdanov AA
Myeloperoxidase Activity Imaging Using (67)Ga Labeled Substrate.
Mol Imaging Biol. 2005;:1-8 - PMID: 16292477
Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH.
Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples
Anal Biochem. 2005;338(1):151-158 - PMID: 15707946
Rabkin-Aikawa E, Mayer J, Schoen F
Heart valve regeneration.
Adv Biochem Eng Biot. 2005;94:141-79 - PMID: 15915872
Low A, O'Donnell C, Kathiresan S, Everett B, Chae C, Shaw S, Ellinor P, MacRae C
Aging syndrome genes and premature coronary artery disease.
BMC Med Genet. 2005;6:38 - PMID: 16262891 - PMCID: PMC1289285
Zhu B, Jaffer F, Nztiachristos V, Weissleder R
Development of a near infrared fluorescence catheter: operating characteristics and feasibility for atherosclerotic plaque detection
J Phys D Appl Phys. 2005;38:2701-2707
Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R
A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation.
Urology. 2005;66(5):1066-71 - PMID: 16286125
Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V.
Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology
Cell Oncol. 2005;27(3):183-90 - PMID: 16037639 - PMCID: PMC4615174
Ripoll J, Ntziachristos V.
Quantitative point source photoacoustic inversion formulas for scattering and absorbing media
Hys Rev E Stat Nonlin Soft Matter Phys. 2005;71(3 Pt 1):031912 - PMID: 15903464
Ueno T, Omura T, Takahashi T, Matsumoto H, Takahashi Y, Kakita A, Yamashina S
Liver transplantation using liver grafts preserved under high pressure.
Artif Organs. 2005;29(10):849-55 - PMID: 16185349
Bouley R, Hawthorn G, Russo L, Lin HY, Ausiello D, Brown D
Aquaporin 2 (AQP2) and vasopressin receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in &quot;endocytosis-resistant&quot; membrane domains after vasopressin treatment.
Abdom Imaging. 2005;:ePub - PMID: 16104839
Grimm J, Wunder A.
Current state of molecular imaging research
Rofo-Fortschr Rontg. 2005;177(3):326-37 - PMID: 15719293
Gao M, Lewis G, Turner GM, Soubret A, Ntziachristos V.
Effects of background fluorescence in fluorescence molecular tomography
Appl Optics. 2005;44(26):5468-74 - PMID: 16161661
Ueno T, Sugino M, Nemoto H, Shoji H, Kakita A, Watanabe M
Effect over time of endotoxin adsorption therapy in sepsis.
Ther Apher Dial. 2005;9(2):128-36 - PMID: 15828924
Chen J, Wasserman B
Vulnerable plaque imaging.
Neuroimag Clin N Am.. 2005;15:609-21, xi - PMID: 16360592
Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T
Mouse Models of Human Non-Small-Cell Lung Cancer: Raising the Bar.
Cold Spring Harb Symp Quant Biol. 2005;70:241-250 - PMID: 16869760
Zeller M, Hunter AD, McCarthy JR, Capetta SH, Bruckner C
Crystal and molecular structure of [5,10,15,20-tetrakisphenyl-2-ethoxy-3-oxa-chlorinato]Ag(II).
J Chem Crystallogr. 2005;35(12):935-42
Sosnovik D, Weissleder R
Magnetic resonance and fluorescence based molecular imaging technologies.
Prog Drug Res. 2005;62:83-115 - PMID: 16329255
Marks DL, Vinegoni C, Bredfeldt J, Boppart SA
Nonlinear Interferometric Vibrational Imaging. efficient detection of Coherent Anti-Stokes Raman Scattering
OPN Special Issue, Optics in 2005. 2005;16:23
Bogdanov AA Jr, Chen JW, Kang HW, Weissleder R.
Magnetic resonance signal amplification probes
Ernst Schering Res Found Workshop. 2005;49:147-57 - PMID: 15524215
Zacharakis G, Ripoli G, Weissleder R, Ntziachristos V
Fluorescent Protein Tomography Scanner for Small Animal Imaging
2005;(24) 7:878-885
Pastor-Soler N, Pietrement C, Breton S
Role of acid/base transporters in the male reproductive tract and potential consequences of their malfunction.
2005;20:417-28 - PMID: 16287991
Peterson R, Shaw S, Peterson T, Milan D, Zhong T, Schreiber S, MacRae C, Fishman M
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.
Nat Biotechnol. 2004;22(5):595-9 - PMID: 15097998
Mahmood U
Near infrared optical applications in molecular imaging. Earlier, more accurate assessment of disease presence, disease course, and efficacy of disease treatment.
IEEE Eng Med Biol. 2004;23(4):58-66 - PMID: 15508386
Harisinghani MG, Weissleder R
Sensitive, noninvasive detection of lymph node metastases.
PLoS Med. 2004;1(3):e66 - PMID: 15630471 - PMCID: PMC539052
Fukumoto Y, Deguchi J, Libby P, Rabkin-Aikawa E, Sakata Y, Chin M, Hill C, Lawler P, Varo N, Schoen F, Krane S, Aikawa M
Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques.
Circulation. 2004;110:1953-9 - PMID: 15451791
Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R
Molecular Imaging of Factor XIIIa Activity in Thrombosis Using a Novel, Near-Infrared Fluorescent Contrast Agent That Covalently Links to Thrombi.
Circulation. 2004;110(2):170-6 - PMID: 15210587
Tsourkas A, Hofstetter O, Hofstetter H, Weissleder R, Josephson L
Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities
Angew Chem Int Ed Engl. 2004;43(18):2395-2399 - PMID: 15114571
Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H
Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors.
Angew Chem Int Ed Engl. 2004;43(2):224-8 - PMID: 14695616
Lee H, Purdon AM, Chu V, Westervelt RM
Controlled Assembly of Magnetic Nanoparticles from Magnetotactic Bacteria Using Microelectromagnets Arrays
Nano Lett. 2004;4(5):995
Perez JM, Simeone FJ, Tsourkas A, Josephson L, Weissleder R
Peroxidase substrate nanosensors for MR imaging
Nano Lett. 2004;4:119-122
de Sousa Lopes S, Roelen B, Monteiro R, Emmens R, Lin HY, Li E, Lawson K, Mummery C
BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo.
Gene Dev. 2004;18(15):1838-49 - PMID: 15289457 - PMCID: PMC517404
Johnson J, Wiley R, Fattouh R, Swirski F, Gajewska B, Coyle A, Gutierrez-Ramos J, Ellis R, Inman M, Jordana M
Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling.
Am J Resp Crit Care. 2004;169(3):378-85 - PMID: 14597485
Jaffer FA, Weissleder R
Seeing within: molecular imaging of the cardiovascular system
Circ Res. 2004;94(4):433-45 - PMID: 15001542
Hilderbrand S, Lim M, Lippard S
Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors.
J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703
Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R
Imaging inflammation of the pancreatic islets in type 1 diabetes.
Proc Natl Acad Sci U S A. 2004;101(34):12634-9 - PMID: 15304647 - PMCID: PMC515109
Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A Jr, Josephson L, Weissleder R
Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate.
Proc Natl Acad Sci U S A. 2004;101(33):12294-9 - PMID: 15304657 - PMCID: PMC514472
Zhao M, Weissleder R
Intracellular cargo delivery using tat peptide and derivatives
Med Res Rev. 2004;24:1-12 - PMID: 14595670
Kunstfeld R, Hirakawa S, Hong Y-K, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin CP, Fiebiger E, Wu Y, Hicklin D, Bohlen P, Detmar M
VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation
Blood. 2004;104:1048-57
Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R
In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas
Cancer Res. 2004;64:273-8 - PMID: 14729634
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Lienard D, Gugerli O, Ferradini L, Robert C, Avril M, Zitvogel L, Angevin E
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Cancer Res. 2004;64:2192-8 - PMID: 15026362
Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS
Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas.
Cancer Res. 2004;64(12):4069-77 - PMID: 15205313
Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R
In Vivo Imaging of ?-Galactosidase Activity Using Far Red Fluorescent Switch
Cancer Res. 2004;64:1579-1583 - PMID: 14996712
Grimm J, Perez JM, Josephson L, Weissleder R
Novel nanosensors for rapid analysis of telomerase activity
Cancer Res. 2004;64:639-43 - PMID: 14744779
Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R
Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide.
Cancer Res. 2004;64(17):6247-51 - PMID: 15342411
Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Lienard D, Lejeune F, Rimoldi D, Guillaume P, Meidenbauer N, Mackensen A, Rufer N, Lubenow N, Speiser D, Cerottini J, Romero P, Pittet M
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.
Cancer Res. 2004;64:2865-73 - PMID: 15087405
Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP
In vivo flow cytometry: a new method for enumerating circulating cancer cells.
Cancer Res. 2004;64(15):5044-7 - PMID: 15289300 - PMCID: PMC2824432
Meidenbauer N, Zippelius A, Pittet M, Laumer M, Vogl S, Heymann J, Rehli M, Seliger B, Schwarz S, Le Gal F, Dietrich P, Andreesen R, Romero P, Mackensen A
High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma.
Cancer Res. 2004;64:6319-26 - PMID: 15342421
Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO
Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy
Cancer Res. 2004;64(9):3236-42 - PMID: 15126365
Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.
Arth Rheum/AR C Res. 2004;50(8):2459-65 - PMID: 15334458
Samad T, Srinivasan A, Karchewski L, Jeong S, Campagna J, Ji R, Fabrizio D, Zhang Y, Lin HY, Bell E, Woolf C
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
J Neurosci. 2004;24(8):2027-36 - PMID: 14985445
Funovics MA, Weissleder R, Mahmood U
Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice.
Radiology. 2004;231(3):659-66 - PMID: 15163807
Mahmood U
Can MR Imaging Be Used to Track Delivery of Intravascularly Administered Stem Cells?
Radiology. 2004;233(3):625-6 - PMID: 15564396
Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP
MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo.
Int J Cancer. 2004;112(6):986-93 - PMID: 15386354
Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R
Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model
Stroke. 2004;35:952-7 - PMID: 14988578
Law B, Curino A, Bugge TH, Weissleder R, Tung CH
Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter.
Chem Biol. 2004;11(1):99-106 - PMID: 15112999
Zippelius A, Bioley G, Le Gal F, Rufer N, Brandes M, Batard P, De Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Pittet M
Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues.
J Immunol. 2004;172:2773-7 - PMID: 14978076
Messerli SM, Prabhakar S, Tang Y, Shah K, Cortes ML, Murthy V, Weissleder R, Breakefield XO, Tung CH
A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe.
Neoplasia. 2004;6(2):95-105 - PMID: 15140398 - PMCID: PMC1502090
Swirski F, Gajewska B, Robbins C, D'Sa A, Johnson J, Pouladi M, Inman M, Stampfli M
Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta, breaks established inhalation tolerance.
Eur J Immunol. 2004;34(9):2375-86 - PMID: 15307170
Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM
Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells.
J Gen Physiol. 2004;124(4):395-407 - PMID: 15452200 - PMCID: PMC2233909
del Re E, Babitt J, Pirani A, Schneyer A, Lin HY
In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2.
J Biol Chem. 2004;279(21):22765-72 - PMID: 14996829
del Re E, Sidis Y, Fabrizio D, Lin HY, Schneyer A
Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system.
J Biol Chem. 2004;279(51):53126-35 - PMID: 15475360
Nolan E, Burdette S, Harvey J, Hilderbrand S, Lippard S
Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform.
Inorg Chem. 2004;43:2624-35 - PMID: 15074981
Hilderbrand S, Lippard S
Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes.
Inorg Chem. 2004;43:5294-301 - PMID: 15310207
Pham W, Choi Y, Weissleder R, Tung CH
Developing a Peptide-Based Near-Infrared Molecular Probe for Protease Sensing.
Bioconjug Chem. 2004;15(6):1403-1407 - PMID: 15546208
Schellenberger EA, Sosnovik D, Weissleder R, Josephson L
Magneto/Optical annexin v, a multimodal protein.
Bioconjug Chem. 2004;15(5):1062-7 - PMID: 15366960
Banerjee P, Reichardt W, Weissleder R, Bogdanov A Jr
Novel hyperbranched dendron for gene transfer in vitro and in vivo.
Bioconjug Chem. 2004;15(5):960-8 - PMID: 15366948
Kircher MF, Weissleder R, Josephson L
A dual fluorochrome probe for imaging proteases
Bioconjug Chem. 2004;15:242-8 - PMID: 15025519
Metelev V, Weissleder R, Bogdanov A Jr
Synthesis and Properties of Fluorescent NF-kappaB-Recognizing Hairpin Oligodeoxyribonucleotide Decoys.
Bioconjug Chem. 2004;15(6):1481-1487 - PMID: 15546218
Shah K, Jacobs A, Breakefield XO, Weissleder R
Molecular imaging of gene therapy for cancer
Gene Ther. 2004;11(15):1175-87 - PMID: 15141158
Graves EE, Weissleder R, Ntziachristos V
Fluorescence molecular imaging of small animal tumor models.
Curr Mol Med. 2004;4(4):419-30 - PMID: 15354872
Pouladi M, Robbins C, Swirski F, Cundall M, McKenzie A, Jordana M, Shapiro S, Stampfli M
Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice.
Am J Respir Cell Mol Biol. 2004;30(1):84-90 - PMID: 12842850
Robbins C, Dawe D, Goncharova S, Pouladi M, Drannik A, Swirski F, Cox G, Stampfli M
Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness.
Am J Respir Cell Mol Biol. 2004;30(2):202-11 - PMID: 12920055
Schulz RB, Ripoll J, Ntziachristos V
Experimental fluorescence tomography of tissues with noncontact measurements.
IEEE T Med Imaging. 2004;23(4):492-500 - PMID: 15084074
Lienard D, Rimoldi D, Marchand M, Dietrich P, van Baren N, Geldhof C, Batard P, Guillaume P, Ayyoub M, Pittet M, Zippelius A, Fleischhauer K, Lejeune F, Cerottini J, Romero P, Speiser D
Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.
Cancer Immunol Immunther. 2004;4:4 - PMID: 15149168
Marks DL, Vinegoni C, Bredfeldt JS, Boppart SA
Interferometric differentiation between resonant Coherent Anti-Stokes Raman Scattering and nonresonant four-wave-mixing processes
Appl Phys Lett. 2004;85:5787-89
Lee H, Purdon AM, Westervelt RM
Manipulation of biological cells using a microelectromagnet matrix
Appl Phys Lett. 2004;85(6):1063-65
Hunt TP, Lee H, and Westervelt RM
Addressable micropost array for the dielectrophoretic manipulation of particles in fluid
Appl Phys Lett. 2004;85(26):6421-23
Pham W, Kircher MF, Weissleder R, Tung CH
Enhancing membrane permeability by Fatty acylation of oligoarginine peptides.
Chembiochem. 2004;5(8):1148-51 - PMID: 15300843
Schellenberger EA, Reynolds F, Weissleder R, Josephson L
Surface-functionalized nanoparticle library yields probes for apoptotic cells
Chembiochem. 2004;5:275-9 - PMID: 14997519
Schellenberger EA, Weissleder R, Josephson L
Optimal modification of annexin v with fluorescent dyes
Chembiochem. 2004;5:271-4 - PMID: 14997518
Perez JM, Josephson L, Weissleder R
Use of magnetic nanoparticles as nanosensors to probe for molecular interactions
Chembiochem. 2004;5:261-4 - PMID: 14997516
Paunescu TG, Da Silva N, Marshansky V, McKee M, Breton S, Brown D
Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymis.
Am J Physiol Cell Physiol. 2004;287(1):C149-62 - PMID: 15013950
McCarthy JR, Hyland MA, Bruckner C.
Synthesis of indaphyrins: meso-tetraarylsecochlorin-based porphyrinoids containing direct o-phenyl-to-beta-linkages.
Org Biomol Chem. 2004;2(10):1484-91
Vinegoni C, Bredfeldt J, Marks D, Boppart S
Nonlinear optical contrast enhancement for optical coherence tomography.
Opt Express. 2004;12:331-41 - PMID: 19471542
Rabkin-Aikawa E, Aikawa M, Farber M, Kratz J, Garcia-Cardena G, Kouchoukos N, Mitchell M, Jonas R, Schoen F
Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site.
J Thorac Cardiov Sur. 2004;128:552-61 - PMID: