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Lu HA, Matsuzaki T, Bouley R, Hasler U, Qin Q, Brown D

The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.
Am J Physiol Renal Physiol. 2008;295(1):F290-4 - PMID: 18434387 - PMCID: PMC2494506 - DOI: 10.1152/ajprenal.00072.2008

Van Hoek AN, Bouley R, Lu YX, Silberstein CM, Brown D, Wax MB, Patil RV

Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.
Am J Physiol Renal Physiol. 2009;296(6):F1396-404 - PMID: 19297454 - PMCID: PMC2692439 - DOI: 10.1152/ajprenal.00018.2009

Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF

Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression.
Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332 - DOI: 10.1152/ajprenal.90762.2008

Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D

Cyclic AMP stimulates apical V-ATPase accumulation, microvillar elongation and proton extrusion in kidney collecting duct A-intercalated cells.
Am J Physiol Renal Physiol. 2010;298(3):F643-54 - PMID: 20053793 - PMCID: PMC2838605 - DOI: 10.1152/ajprenal.00584.2009

Zhuang Z, Marshansky V, Breton S, Brown D

Is caveolin involved in normal proximal tubule (PT) function? Presence in model PT systems but absence in situ.
Am J Physiol Renal Physiol. 2010;300(1):F199-206 - PMID: 20980408 - PMCID: PMC3023221 - DOI: 10.1152/ajprenal.00513.2010

Li W, Zhang Y, Bouley R, Chen Y, Matsuzaki T, Nunes P, Hasler U, Brown D, Lu HA

Simvastatin Enhances Aquaporin 2 Surface Expression and Urinary Concentration in Vasopressin Deficient Brattleboro Rats through Modulation of Rho GTPase.
Am J Physiol Renal Physiol. 2011;301(2):F309-18 - PMID: 21511701 - PMCID: PMC3154588 - DOI: 10.1152/ajprenal.00001.2011

Breton S, Nsumu NN, Galli T, Sabolic I, Smith PJ, Brown D

Tetanus toxin-mediated cleavage of cellubrevin inhibits proton secretion in the male reproductive tract.
Am J Physiol Renal Physiol. 2000;278(5):F717-25 - PMID: 10807583 - DOI: 10.1152/ajprenal.2000.278.5.F717

Silver RB, Breton S, Brown D

Potassium depletion increases proton pump (H(+)-ATPase) activity in intercalated cells of cortical collecting duct.
Am J Physiol Renal Physiol. 2000;279(1):F195-202 - PMID: 10894802 - DOI: 10.1152/ajprenal.2000.279.1.F195

Bagnis C, Marshansky V, Breton S, Brown D

Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition.
Am J Physiol Renal Physiol. 2001;280(3):F437-48 - PMID: 11181405 - DOI: 10.1152/ajprenal.2001.280.3.F437

Bagnis C, Marsolais M, Biemesderfer D, Laprade R, Breton S

Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis.
Am J Physiol Renal Physiol. 2001;280(3):F426-36 - PMID: 11181404 - DOI: 10.1152/ajprenal.2001.280.3.F426

Breton S, Inoue T, Knepper MA, Brown D

Antigen retrieval reveals widespread basolateral expression of syntaxin 3 in renal epithelia.
Am J Physiol Renal Physiol. 2002;282(3):F523-9 - PMID: 11832435 - DOI: 10.1152/ajprenal.00128.2001

Zharkikh L, Zhu X, Stricklett PK, Kohan DE, Chipman G, Breton S, Brown D, Nelson RD

Renal principal cell-specific expression of green fluorescent protein in transgenic mice.
Am J Physiol Renal Physiol. 2002;283(6):F1351-64 - PMID: 12426236 - DOI: 10.1152/ajprenal.0224.2001

Breton S, Brown D

New insights into the regulation of V-ATPase-dependent proton secretion.
Am J Physiol Renal Physiol. 2006;292(1):F1-10 - PMID: 17032935 - DOI: 10.1152/ajprenal.00340.2006

Bouley R, Nunes P, Andriopoulos B, McLaughlin MM, Webber MJ, Lin HY, Babitt JL, Gardella TJ, Ausiello DA, Brown D

Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.
Am J Physiol Renal Physiol. 2012;304(5):F553-64 - PMID: 23235478 - PMCID: PMC3602717 - DOI: 10.1152/ajprenal.00438.2011

Vedovelli L, Rothermel JT, Finberg KE, Wagner CA, Azroyan A, Hill E, Breton S, Brown D, Paunescu TG

Altered V-ATPase expression in renal intercalated cells isolated from B1-subunit deficient mice by fluorescence activated cell sorting.
Am J Physiol Renal Physiol. 2012;304(5):F522-32 - PMID: 23269648 - PMCID: PMC3602708 - DOI: 10.1152/ajprenal.00394.2012

Paunescu TG, Lu HA, Russo LM, Pastor-Soler NM, McKee M, McLaughlin MM, Bartlett BE, Breton S, Brown D

Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells.
Am J Physiol Renal Physiol. 2013;305(12):F1783-F1795 - PMID: 24133120 - PMCID: PMC3882446 - DOI: 10.1152/ajprenal.00622.2012

Lu H, Sun TX, Bouley R, Blackburn K, McLaughlin M, Brown D

Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2.
Am J Physiol Renal Physiol. 2003;286(2):F233-43 - PMID: 14519593 - DOI: 10.1152/ajprenal.00179.2003

Herak-Kramberger CM, Breljak D, Ljubojević M, Matokanovic M, Lovric M, Rogic D, Brzica H, Vrhovac I, Karaica D, Micek V, Ivkovic Dupor J, Brown D, Sabolic I

Sex-dependent expression of water channel AQP1 along the rat nephron.
Am J Physiol Renal Physiol. 2015;308(8):F809-21 - PMID: 25656365 - PMCID: PMC4398837 - DOI: 10.1152/ajprenal.00368.2014

Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ

Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells.
Am J Physiol Renal Physiol. 2015;309(8):F673-9 - PMID: 26290367 - PMCID: PMC4609919 - DOI: 10.1152/ajprenal.00152.2015

David V, Francis C, Babitt JL

Ironing out the crosstalk between FGF23 and inflammation.
Am J Physiol Renal Physiol. 2016;312(1):F1-F8 - PMID: 27582104 - PMCID: PMC5283889 - DOI: 10.1152/ajprenal.00359.2016

Mamuya FA, Cano-Peñalver JL, Li WU, Rodriguez-Puyol D, Rodríguez-Puyol M, Brown D, de Frutos S, Lu HJ

ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway.
Am J Physiol Renal Physiol. 2016;311(6):F1346-F1357 - PMID: 27760768 - PMCID: PMC5210194 - DOI: 10.1152/ajprenal.00336.2016

Cheung PW, Ueberdiek L, Day J, Bouley R, Brown D

Protein phosphatase 2C (PP2C) is responsible for VP-induced dephosphorylation of AQP2 serine 261.
Am J Physiol Renal Physiol. 2017;313(2):F404-F413 - PMID: 28381458 - PMCID: PMC5582913 - DOI: 10.1152/ajprenal.00004.2017

Mamuya FA, Xie D, Lei L, Huang M, Tsuji K, Capen DE, Yang B, Weissleder R, Păunescu TG, Lu HJ

Deletion of β-1 integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis.
Am J Physiol Renal Physiol. 2017;313(4):F1026-F1037 - PMID: 28701310 - PMCID: PMC5668581 - DOI: 10.1152/ajprenal.00038.2017

Alper SL, Stuart-Tilley AK, Biemesderfer D, Shmukler BE, Brown D

Immunolocalization of AE2 anion exchanger in rat kidney.
Am J Physiol Renal Physiol. 1997;273(4):F601-F614 - PMID: 29587100 - DOI: 10.1152/ajprenal.1997.273.4.F601

Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA

Localization of the high-affinity glutamate transporter EAAC1 in rat kidney.
Am J Physiol Renal Physiol. 1997;273(6):F1023-F1029 - PMID: 29586122 - DOI: 10.1152/ajprenal.1997.273.6.F1023

Kawachi H, Kurihara H, Topham PS, Brown D, Shia MA, Orikasa M, Shimizu F, Salant DJ

Slit diaphragm-reactive nephritogenic MAb 5-1-6 alters expression of ZO-1 in rat podocytes.
Am J Physiol Renal Physiol. 1997;273(6):F984-F993 - PMID: 29586119 - DOI: 10.1152/ajprenal.1997.273.6.F984

Brown D, Lee R, Bonventre JV

Redistribution of villin to proximal tubule basolateral membranes after ischemia and reperfusion.
Am J Physiol Renal Physiol. 1997;273(6):F1003-F1012 - PMID: 29586118 - DOI: 10.1152/ajprenal.1997.273.6.F1003

Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R

Platinum Compounds for High-Resolution In Vivo Cancer Imaging.
ChemMedChem. 2014;9(6):1131-5 - PMID: 24504646 - PMCID: PMC4037345 - DOI: 10.1002/cmdc.201300502

Keliher EJ, Klubnick JA Reiner T, Mazitschek R, Weissleder R

Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes.
ChemMedChem. 2014;9(7):1368-73 - PMID: 24596307 - PMCID: PMC4145401 - DOI: 10.1002/cmdc.201300506

Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, Wirth DF, André V, Duarte MT, Guedes RC, J V A Dos Santos D, Rosenthal PJ, Mazitschek R, Prudêncio M, Moreira R

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.
ChemMedChem. 2016;11(19):2194-2204 - PMID: 27538856 - DOI: 10.1002/cmdc.201600327

Montet X, Rajopadhye M, Weissleder R.

An albumin-activated far-red fluorochrome for in vivo imaging
ChemMedChem. 2006;1(1):66-69 - PMID: 16892337 - DOI: 10.1002/cmdc.200500028

Choi YD, McCarthy J, Weissleder R, Tung CH

Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy
ChemMedChem. 2006;1(4):458-463 - PMID: 16892381 - DOI: 10.1002/cmdc.200500036

Choi Y, Weissleder R, Tung CH

Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate.
ChemMedChem. 2006;1:698-701 - PMID: 16902920 - DOI: 10.1002/cmdc.200600053

McCarthy JR, Weissleder R

Model Systems for Fluorescence and Singlet Oxygen Quenching by Metalloporphyrins.
ChemMedChem. 2007;2:360-365 - PMID: 17245681 - DOI: 10.1002/cmdc.200600244

Blazer-Yost BL, Paunescu TG, Helman SI, Lee KD, Vlahos CJ

Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption.
Am J Physiol. 1999;277(3 Pt 1):C531-6 - PMID: 10484339 - DOI: 10.1152/ajpcell.1999.277.3.C531

Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R

High-Yielding, Two-Step (18) F Labeling Strategy for (18) F-PARP1 Inhibitors.
ChemMedChem. 2011;6(3):424-7 - PMID: 21360818 - PMCID: PMC3136544 - DOI: 10.1002/cmdc.201000426

Beck JS, Breton S, Laprade R, Giebisch G

Volume regulation and intracellular calcium in the rabbit proximal convoluted tubule.
Am J Physiol. 1991;260(6 Pt 2):F861-7 - PMID: 2058707 - DOI: 10.1152/ajprenal.1991.260.6.F861

Beck JS, Breton S, Mairb

Relationship between sodium transport and intracellular ATP in isolated perfused rabbit proximal convoluted tubule.
Am J Physiol. 1991;261(4 Pt 2):F634-9 - PMID: 1928376 - DOI: 10.1152/ajprenal.1991.261.4.F634

Beck JS, Breton S, Giebisch G, Laprade R

Potassium conductance regulation by pH during volume regulation in rabbit proximal convoluted tubules.
Am J Physiol. 1992;263(3 Pt 2):F453-8 - PMID: 1415573 - DOI: 10.1152/ajprenal.1992.263.3.F453

Breton S, Beck JS, Cardinal J, Giebisch G, Laprade R

Involvement and source of calcium in volume regulatory decrease of collapsed proximal convoluted tubule.
Am J Physiol. 1992;263(4 Pt 2):F656-64 - PMID: 1415737 - DOI: 10.1152/ajprenal.1992.263.4.F656

Macri P, Breton S, Beck JS, Cardinal J, Laprade R

Basolateral K+, Cl-, and HCO3- conductances and cell volume regulation in rabbit PCT.
Am J Physiol. 1993;264(2 Pt 2):F365-76 - PMID: 8447445 - DOI: 10.1152/ajprenal.1993.264.2.F365

Breton S, Beck JS, Laprade R

cAMP stimulates proximal convoluted tubule Na(+)-K(+)-ATPase activity.
Am J Physiol. 1994;266(3 Pt 2):F400-10 - PMID: 8160788 - DOI: 10.1152/ajprenal.1994.266.3.F400

Breton S, Alper SL, Gluck SL, Sly WS, Barker JE, Brown D

Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice.
Am J Physiol. 1995;269(6 Pt 2):F761-74 - PMID: 8594870 - DOI: 10.1152/ajprenal.1995.269.6.F761

Breton S, Marsolais M, Laprade R

Hypotonicity increases basolateral taurine permeability in rabbit proximal convoluted tubule.
Am J Physiol. 1995;268(4 Pt 2):F595-603 - PMID: 7733316 - DOI: 10.1152/ajprenal.1995.268.4.F595

Breton S, Belachgar F, Marsolais M, Lapointe JY, Laprade R

Inhibition of basolateral potassium conductance by taurine in the proximal convoluted tubule.
Am J Physiol. 1996;271(5 Pt 2):F1012-9 - PMID: 8945995 - DOI: 10.1152/ajprenal.1996.271.5.F1012

Breton S, Hammar K, Smith PJ, Brown D

Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport.
Am J Physiol. 1998;275(4 Pt 1):C1134-42 - PMID: 9755067 - DOI: 10.1152/ajpcell.1998.275.4.C1134

Emma F, Breton S, Morrison R, Wright S, Strange K

Effect of cell swelling on membrane and cytoplasmic distribution of pICln.
Am J Physiol. 1998;274(6 Pt 1):C1545-51 - PMID: 9696697 - DOI: 10.1152/ajpcell.1998.274.6.C1545

Derbyshire ER, Mazitschek R, Clardy J

Characterization of Plasmodium Liver Stage Inhibition by Halofuginone.
ChemMedChem. 2012;7(5):844-9 - PMID: 22438279 - PMCID: PMC3359061 - DOI: 10.1002/cmdc.201200045

Schleyer K, Halabi EA, Weissleder R

γ-Butyrolactone derivatives of MSA-2 are STING prodrugs
ChemMedChem. 2024;19(19):e202400416 - PMID: 38887174 - PMCID: PMC11979874 - DOI: 10.1002/cmdc.202400416

McCarthy JR, Hyland MA, Bruckner C.

Synthesis of indaphyrins: meso-tetraarylsecochlorin-based porphyrinoids containing direct o-phenyl-to-beta-linkages.
Org Biomol Chem. 2004;2(10):1484-91
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