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Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation.
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Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC

A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever.
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Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R

Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response
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Beam AL, Kartoun U, Pai JK, Chatterjee AK, Fitzgerald TP, Shaw SY, Kohane IS

Predictive Modeling of Physician-Patient Dynamics That Influence Sleep Medication Prescriptions and Clinical Decision-Making.
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Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA

Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.
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Turcotte R, Alt C, Runnels JM, Ito K, Wu JW, Zaher W, Mortensen LJ, Silberstein L, Côté DC, Kung AL, Ito K, Lin CP

Image-guided transplantation of single cells in the bone marrow of live animals.
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Yang KS, O'Shea A, Zelga P, Liss AS, Del Castillo CF, Weissleder R

Extracellular vesicle analysis of plasma allows differential diagnosis of atypical pancreatic serous cystadenoma.
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Bagramyan A, Lin CP

Miniaturized microscope for non-invasive imaging of leukocyte-endothelial interaction in human microcirculation.
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Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA, Wang X, Chen Y, Placzek M, Williams NS, Hooker J, Herz J, Mazitschek R, Haggarty SJ

Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia.
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Landeros C, Oh J, Weissleder R, Lee H

Deep learning pipeline for automated cell profiling from cyclic imaging
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Nairz M, Haschka D, Dichtl S, Sonnweber T, Schroll A, Aßhoff M, Mindur JE, Moser PL, Wolf D, Swirski FK, Theurl I, Cerami A, Brines M, Weiss G

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis.
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Brannen A, Eggert M, Nahrendorf M, Arnold R, Panizzi P

Correlation of 360-degree Surface Mapping In Vivo Bioluminescence with Multi-Spectral Optoacoustic Tomography in Human Xenograft Tumor Models.
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Yeh SA, Wilk K, Lin CP, Intini G

In Vivo 3D Histomorphometry Quantifies Bone Apposition and Skeletal Progenitor Cell Differentiation.
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Aganj I, Harisinghani MG, Weissleder R, Fischl B

Unsupervised medical image segmentation based on the local center of mass
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Vasaturo M, Cotugno R, Fiengo L, Vinegoni C, Dal Piaz F, De Tommasi N

The anti-tumor diterpene oridonin is a direct inhibitor of Nucleolin in cancer cells.
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Kim SJ*, Wang C*, Zhao B, Im H, Min J, Choi HJ, Tadros J, Choi NR, Castro CM, Weissleder R, Lee H, Lee K

Deep transfer learning-based hologram classification for molecular diagnostics.
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Carvajal G, Brukman NG, Weigel Muñoz M, Battistone MA, Guazzone VA, Ikawa M, Haruhiko M, Lustig L, Breton S, Cuasnicu PS

Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4.
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Tan X, Patil R, Bartosik P, Runnels JM, Lin CP, Niedre M

In Vivo Flow Cytometry of Extremely Rare Circulating Cells.
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Zaborowski MP, Cheah PS, Zhang X, Bushko I, Lee K, Sammarco A, Zappulli V, Maas SLN, Allen RM, Rumde P, György B, Aufiero M, Schweiger MW, Lai CP, Weissleder R, Lee H, Vickers KC, Tannous BA, Breakefield XO

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles.
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Figueiredo JL, Santa-Cruz F, Lima-Filho JL, Hilgendorf I, Aikawa M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK, Robbins CS

A durable murine model of spleen transplantation with arterial and venous anastomoses.
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Vinegoni C, Fumene Feruglio P, Courties G, Schmidt S, Hulsmans M, Lee S, Wang R, Sosnovik D, Nahrendorf M, Weissleder R

Fluorescence microscopy tensor imaging representations for large-scale dataset analysis.
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Hou J, Lin CP, Intini G

Activation of creER recombinase in the mouse calvaria induces local recombination without effects on distant skeletal segments.
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Bozhko D, Osborn EA, Rosenthal A, Verjans JW, Hara T, Kellnberger S, Wissmeyer G, Ovsepian SV, McCarthy JR, Mauskapf A, Stein AF, Jaffer FA, Ntziachristos V

Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo.
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Bhatia RS, Kumar V, Picard MH, Weiner RB

Comparison of the 2008 and 2011 appropriate use criteria for stress echocardiography.
J Am Soc Echocardiogr. 2013;26(4):339-43 - PMID: 23313389 - DOI: 10.1016/j.echo.2012.12.001

Pang Y, Tsigkou O, Spencer JA, Lin CP, Neville C, Grottkau B

Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing.
Tissue Eng Part C Methods. 2015;21(10):1025-1031 - PMID: 25962617 - PMCID: PMC4593976 - DOI: 10.1089/ten.TEC.2015.0091

Liu J, Wang W, Liu M, Su L, Zhou H, Xia Y, Ran J, Lin HY, Yang B

Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.
Cell Signal. 2016;28(12):1842-1851 - PMID: 27575743 - DOI: 10.1016/j.cellsig.2016.08.015

Abou Haidar E, Prabhakar S, Geffrey AL, Mahamdeh M, Tomeh T, Breyne K, Roumieh E, Gurevich M, Soberman RJ, Wojtkiewicz GR, Chen JW, Han JS, Stemmer-Rachamimov A, Breakefield XO

AAV hamartin gene therapy in a stochastic, cerebral mouse model of tuberous sclerosis type 1.
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Zhao WN, Ghosh B, Tyler M, Lalonde J, Joseph NF, Kosaric N, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ

Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory.
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Graves EE, Weissleder R, Ntziachristos V

Fluorescence molecular imaging of small animal tumor models.
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Russo LM, Brown D, Lin HY

The soluble transforming growth factor-beta receptor: Advantages and applications.
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Robbins C, Dawe D, Goncharova S, Pouladi M, Drannik A, Swirski F, Cox G, Stampfli M

Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness.
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Pouladi M, Robbins C, Swirski F, Cundall M, McKenzie A, Jordana M, Shapiro S, Stampfli M

Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice.
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Gajewska B, Swirski F, Alvarez D, Ritz S, Goncharova S, Cundall M, Snider D, Coyle A, Gutierrez-Ramos J, Stampfli M, Jordana M

Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation.
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Kim JK, Vinarsky V, Wain JC, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH

In vivo imaging of tracheal epithelial cells in mice during airway regeneration.
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Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ

Crebinostat: A Novel cognitive enhancer that inhibits Histone Deacetylase activity and Modulates Chromatin-mediated Neuroplasticity.
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Nairz M, Theurl I, Swirski FK, Weiss G

"Pumping iron" - how macrophages handle iron at the systemic, microenvironmental, and cellular levels.
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Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Gruber G, Marshansky V

The N-terminus of a-Subunit Isoforms is Involved in Signaling between V-ATPase and Cytohesin-2.
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Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD, Hallows KR, Brown D, Bouley R, Vilardaga JP

Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.
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Zumbrennen-Bullough K, Wu Q, Core AB, Canali S, Chen W, Theurl I, Meynard D, Babitt JL

MicroRNA-130a is upregulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription.
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Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW

ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
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Oza AM, Tinker AV, Oaknin A, Shapira-Frommer R, McNeish IA, Swisher EM, Ray-Coquard I, Bell-McGuinn K, Coleman RL, O'Malley DM, Leary A, Chen LM, Provencher D, Ma L, Brenton JD, Konecny GE, Castro CM, Giordano H, Maloney L, Goble S, Lin KK, Sun J, Raponi M, Rolfe L, Kristeleit RS

Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2.
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Beaulieu V, Da Silva N, Pastor-Soler N, Brown CR, Smith PJ, Brown D, Breton S

Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling.
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Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D

Heat shock protein 70 interacts with aquaporin-2 (AQP2) and regulates its trafficking.
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Pietrement C, Da Silva N, Silberstein C, James M, Marsolais M, Van Hoek A, Brown D, Pastor-Soler N, Ameen N, Laprade R, Ramesh V, Breton S

Role of NHERF1, CFTR and cAMP in the regulation of aquaporin 9
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Johnson E, Lee Y, Sander T, Rabkin E, Schoen F, Kaushal S, Bischoff J

NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells.
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Shah K, Vervoort J, de Vries S

Role of threonines in the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 activation loop in phosphorylation.
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Xia Y, Yu P, Sidis Y, Beppu H, Bloch K, Schneyer A, Lin H

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.
J Biol Chem. 2007;282(25):18129-40 - PMID: 17472960 - DOI: 10.1074/jbc.M701679200

Babitt J, Zhang Y, Samad T, Xia Y, Tang J, Campagna J, Schneyer A, Woolf C, Lin HY

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.
J Biol Chem. 2005;280(33):29820-7 - PMID: 15975920 - DOI: 10.1074/jbc.M503511200

del Re E, Sidis Y, Fabrizio D, Lin HY, Schneyer A

Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system.
J Biol Chem. 2004;279(51):53126-35 - PMID: 15475360 - DOI: 10.1074/jbc.M408090200

del Re E, Babitt J, Pirani A, Schneyer A, Lin HY

In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2.
J Biol Chem. 2004;279(21):22765-72 - PMID: 14996829 - DOI: 10.1074/jbc.M401350200
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