CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD.
Blood. 2003;101(10):4033-41 - PMID: 12576324 - DOI: 10.1182/blood-2002-01-0324
hnRNP-K and Pur(alpha) act together to repress the transcriptional activity of the CD43 gene promoter.
Blood. 2002;100(10):3536-44 - PMID: 12411317 - DOI: 10.1182/blood.V100.10.3536
Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192 - DOI: 10.1182/blood-2014-08-593426
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression.
Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
Blood. 2016;127(19):2327-36 - PMID: 26755707 - PMCID: PMC4865590 - DOI: 10.1182/blood-2015-11-681494
Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice.
Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice.
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin.
Blood. 2008;111(10):5195-204 - PMID: 18326817 - PMCID: PMC2384142 - DOI: 10.1182/blood-2007-09-111567
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.
Blood. 2003;102:1779-87 - PMID: 12750165 - DOI: 10.1182/blood-2003-02-0420
Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells.
Blood. 2002;99:1620-6 - PMID: 11861276 - DOI: 10.1182/blood.v99.5.1620
microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922 - DOI: 10.1182/blood-2009-01-198408
Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma.
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation
Blood. 2004;104:1048-57
Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders.
Blood. 2008;112(6):2546-53 - PMID: 18535200 - DOI: 10.1182/blood-2008-03-146415
Response: Other factors may contribute to differences between sickle cell and non-sickle cell patients.
Blood. 2010;115(21):4315-6 - PMID: 20508172
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats.
Blood. 2011;118(18):4977-84 - PMID: 21730356 - PMCID: PMC3208302 - DOI: 10.1182/blood-2011-03-345066
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801 - DOI: 10.1182/blood-2011-03-345165
Engineered cell homing.
Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725 - DOI: 10.1182/blood-2010-10-311464
Defining the role of TORC1 and TORC2 in multiple myeloma.
Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208 - DOI: 10.1182/blood-2011-03-342394
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment.
Preclinical activity, pharmacodynamic and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma.
Blood. 2012;119(11):2579-89 - PMID: 22262760 - PMCID: PMC3337713 - DOI: 10.1182/blood-2011-10-387365
Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection.
Blood. 2006;108(12):3801-7 - PMID: 16912225 - DOI: 10.1182/blood-2006-03-013235
Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features.
Blood. 2012;119(24):5782-94 - PMID: 22394600 - PMCID: PMC3382938 - DOI: 10.1182/blood-2011-09-380410
Clonal Hematopoiesis of Indeterminate Potential and Risk of Death from COVID-19.
Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors.
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate.
Cell Stem Cell. 2024;31(3):359-377.e10 - PMID: 38458178 - PMCID: PMC10957094 - DOI: 10.1016/j.stem.2024.02.004
Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress.
Cell Stem Cell. 2019;24(6):944-957.e5 - PMID: 31006621 - PMCID: PMC6597014 - DOI: 10.1016/j.stem.2019.03.020
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.
Cell Stem Cell. 2019;25(4):570-583.e7 - PMID: 31279774 - PMCID: PMC6778015 - DOI: 10.1016/j.stem.2019.06.003
A new image of the hematopoietic stem cell vascular niche.
Cell Stem Cell. 2013;13(5):514-6 - PMID: 24209758 - PMCID: PMC4148778 - DOI: 10.1016/j.stem.2013.10.012
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Cell Stem Cell. 2015;16 (5):477-487 - PMID: 25957903 - PMCID: PMC4426344 - DOI: 10.1016/j.stem.2015.04.008
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.
Cell Stem Cell. 2016;19(4):530-543 - PMID: 27524439 - PMCID: PMC5402355 - DOI: 10.1016/j.stem.2016.07.004
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.
Cell Stem Cell. 2016;20(2):233-246.e7 - PMID: 27989769 - PMCID: PMC5291795 - DOI: 10.1016/j.stem.2016.11.003
Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network.
Cell Stem Cell. 2010;6(6):591-602 - PMID: 20569696 - PMCID: PMC2897075 - DOI: 10.1016/j.stem.2010.03.016
Reprogramming factor expression initiates widespread targeted chromatin remodeling.
Cell Stem Cell. 2011;8(1):96-105 - PMID: 21211784 - PMCID: PMC3220622 - DOI: 10.1016/j.stem.2010.12.001
Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration.
Cell Stem Cell. 2012;10(3):259-72 - PMID: 22385654 - PMCID: PMC3652251 - DOI: 10.1016/j.stem.2012.02.003
Fatty acid synthesis is required for breast cancer brain metastasis.
Nat Cancer. 2021;2(4):414-428 - PMID: 34179825 - PMCID: PMC8223728 - DOI: 10.1038/s43018-021-00183-y
Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors.
Nat Cancer. 2024;5(11):1681-1696 - PMID: 39406916 - PMCID: PMC11584400 - DOI: 10.1038/s43018-024-00840-y
Assessment of Combined Nivolumab and Bevacizumab in Relapsed Ovarian Cancer: A Phase 2 Clinical Trial.
JAMA Oncol. 2019;5(12):1731-1738 - PMID: 31600397 - PMCID: PMC6802049 - DOI: 10.1001/jamaoncol.2019.3343
Comparing Adjuvant vs Early-Salvage Radiotherapy After Radical Prostatectomy-Reply.
JAMA Oncol. 2018;4(11):1620-1621 - PMID: 30422248 - DOI: 10.1001/jamaoncol.2018.3552
Comparison Between Adjuvant and Early-Salvage Postprostatectomy Radiotherapy for Prostate Cancer With Adverse Pathological Features.
JAMA Oncol. 2018;4(5):e175230 - PMID: 29372236 - PMCID: PMC5885162 - DOI: 10.1001/jamaoncol.2017.5230
Clinical Outcomes in Patients With Metastatic Lung Cancer Treated With PD-1/PD-L1 Inhibitors and Thoracic Radiotherapy.
JAMA Oncol. 2018;4(2):253-255 - PMID: 28973343 - PMCID: PMC5838581 - DOI: 10.1001/jamaoncol.2017.3808
Development of Integrated Systems for On-Site Infection Detection.
Acc Chem Res. 2021;54(21):3991-4000 - PMID: 34677927 - PMCID: PMC9099220 - DOI: 10.1021/acs.accounts.1c00498
Advances in Biosensor Technologies for Infection Diagnostics.
Acc Chem Res. 2022;55(2):121-122 - PMID: 35038867 - DOI: 10.1021/acs.accounts.1c00647
Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and ARDS.
Am J Respir Crit Care Med. 2022;206(7):857-873 - PMID: 35671465 - PMCID: PMC9799276 - DOI: 10.1164/rccm.202109-2150OC
Biomedical Applications of Tetrazine Cycloadditions.
Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy.