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McCarthy JR
The future of theranostic nanoagents.
Nanomedicine. 2009;4(7):693-5 - PMID: 19839803 - DOI: 10.2217/nnm.09.58
Engelmayr G, Rabkin E, Sutherland F, Schoen F, Mayer J, Sacks M
The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue.
Biomaterials . 2005;26:175-87 - PMID: 15207464 - DOI: 10.1016/j.biomaterials.2004.02.035
Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS
The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells.
Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971 - DOI: 10.1016/j.biomaterials.2009.10.019
Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA
Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction.
Biomaterials . 2010;32(4):1102-9 - PMID: 21035182 - PMCID: PMC6805145 - DOI: 10.1016/j.biomaterials.2010.10.005
Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG
Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics.
Biomaterials . 2012;33(20):5004-12 - PMID: 22494889 - PMCID: PMC3366278 - DOI: 10.1016/j.biomaterials.2012.03.065
Sosnovik DE, Weissleder R
Emerging concepts in molecular MRI.
Curr Opin Biotech. 2007;18(1):4-10 - PMID: 17126545 - DOI: 10.1016/j.copbio.2006.11.001
Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.
Arth Rheum/AR C Res. 2004;50(8):2459-65 - PMID: 15334458 - DOI: 10.1002/art.20379
Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B
Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis.
Arth Rheum/AR C Res. 2007;56(1):117-128 - PMID: 17195214 - DOI: 10.1002/art.22303
Mendenhall E, Bernstein B
Chromatin state maps: new technologies, new insights.
Curr Opin Genet Dev. 2008;18(2):109-15 - PMID: 18339538 - PMCID: PMC2486450 - DOI: 10.1016/j.gde.2008.01.010
Khazaie K, von Boehmer H
The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer.
Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370 - DOI: 10.1016/j.semcancer.2005.11.006
Speiser D, Pittet M, Rimoldi D, Guillaume P, Luescher I, Lienard D, Lejeune F, Cerottini J, Romero P
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.
Semin Cancer Biol. 2003;13:461-72 - PMID: 15001165 - DOI: 10.1016/j.semcancer.2003.09.010
Shah K, Tang Y, Breakefield X, Weissleder R
Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo
Oncogene. 2003;22:6865-72 - PMID: 14534533 - DOI: 10.1038/sj.onc.1206748
van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K
Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors.
Oncogene. 2010;29(22):3185-95 - PMID: 20305695 - PMCID: PMC3390229 - DOI: 10.1038/onc.2010.75
Helman E, Naxerova K, Kohane IS
DNA hypermethylation in lung cancer is targeted at differentiation-associated genes.
Oncogene. 2011;31(9):1181-8 - PMID: 21804601 - DOI: 10.1038/onc.2011.307
Trink B, Pai SI, Spunt SL, Raman V, Cairns P, Jen J, Gabrielson E, Sukumar S, Sidransky D
Absence of TSG101 transcript abnormalities in human cancers.
Oncogene. 1998;16(21):2815-8 - PMID: 9652749 - DOI: 10.1038/sj.onc.1201795
Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.
Mol Ther Nucleic Acids. 2012;1:e4 - PMID: 23344621 - PMCID: PMC3381593 - DOI: 10.1038/mtna.2011.3
Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO.
Codon-optimized gaussia luciferase cDNA for Mammalian gene expression in culture and in vivo
Mol Ther. 2005;11(3):435-43 - PMID: 15727940 - DOI: 10.1016/j.ymthe.2004.10.016
Shah K, Tung CH, Breakefield X, Weissleder R.
In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis
Mol Ther. 2005;11 (6):926-931 - PMID: 15922963 - DOI: 10.1016/j.ymthe.2005.01.017
Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA
Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging.
Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149 - DOI: 10.1016/j.ymthe.2006.08.008
Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P
Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma.
Mol Ther. 2010;18(6):1130-42 - PMID: 20179672 - PMCID: PMC2889737 - DOI: 10.1038/mt.2010.29
Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL
Bevacizumab With Angiostatin-armed oHSV Increases Antiangiogenesis and Decreases Bevacizumab-induced Invasion in U87 Glioma.
Mol Ther. 2011;20(1):37-45 - PMID: 21915104 - PMCID: PMC3255598 - DOI: 10.1038/mt.2011.187
Noh KH, Kang TH, Kim JH, Pai SI, Lin KY, Hung CF, Wu TC, Kim TW
Activation of Akt as a mechanism for tumor immune evasion.
Mol Ther. 2008;17(3):439-47 - PMID: 19107122 - PMCID: PMC2835083 - DOI: 10.1038/mt.2008.255
Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R.
Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy
Int J Radiat Oncol Biol Phys. 2005;63(4):1262-9 - PMID: 16253781 - DOI: 10.1016/j.ijrobp.2005.07.952
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG
Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223 - DOI: 10.1016/j.ijrobp.2009.02.052
Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG
Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer.
Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160 - DOI: 10.1016/j.ijrobp.2009.06.002
Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T
Imaging Primary Lung Cancers in Mice to Study Radiation Biology.
Int J Radiat Oncol Biol Phys. 2010;76(4):973-977 - PMID: 20206017 - PMCID: PMC2847457 - DOI: 10.1016/j.ijrobp.2009.11.038
Kirsch DG, Grimm J, Guimaraes AR, Weissleder R
In response to dr. Garbow and colleagues.
Int J Radiat Oncol Biol Phys. 2011;79(3):959 - PMID: 21281902
Basilion JP, Yeon S, Botnar R
Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality.
Curr Top Dev Biol. 2005;70(c):1-33 - PMID: 16338335 - DOI: 10.1016/S0070-2153(05)70001-6
Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ
WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud.
Curr Top Dev Biol. 2010;20(22):1993-2002 - PMID: 21055947 - PMCID: PMC2998074 - DOI: 10.1016/j.cub.2010.09.063
Mahmood U, Josephson L
Molecular MR Imaging Probes
P IEEE. 0;93 (4):800-808
Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model.
J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321 - DOI: 10.1523/JNEUROSCI.0296-08.2008
Samad T, Srinivasan A, Karchewski L, Jeong S, Campagna J, Ji R, Fabrizio D, Zhang Y, Lin HY, Bell E, Woolf C
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties.
J Neurosci. 2004;24(8):2027-36 - PMID: 14985445 - PMCID: PMC6730385 - DOI: 10.1523/JNEUROSCI.4115-03.2004
Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA
The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling.
J Neurosci. 2011;31(50):18391-18400 - PMID: 22171041 - PMCID: PMC3243947 - DOI: 10.1523/JNEUROSCI.4550-11.2011
Lee H, Liu Y, Ham D, Westervelt RM
Integrated cell manipulation system--CMOS/microfluidic hybrid.
Lab Chip. 2007;7(3):331-7 - PMID: 17330164 - DOI: 10.1039/b700373k
Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H
Self-assembled magnetic filter for highly efficient immunomagnetic separation.
Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961 - DOI: 10.1039/c0lc00149j
Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H
Miniature magnetic resonance system for point-of-care diagnostics.
Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660 - DOI: 10.1039/c1lc20177h
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY
On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics.
Lab Chip. 2012;12(17):3103-10 - PMID: 22760641 - PMCID: PMC3411869 - DOI: 10.1039/c2lc40337d
Lindquist NC, Lesuffleur A, Im H, Oh SH
Sub-micron resolution surface plasmon resonance imaging enabled by nanohole arrays with surrounding Bragg mirrors for enhanced sensitivity and isolation.
Lab Chip. 2008;9(3):382-7 - PMID: 19156286 - DOI: 10.1039/b816735d
Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ
Genetic and Clinical Correlates of Early Outgrowth Colony Forming Units.
Circ Cardiovasc Genet. 2011;4(3):296-304 - PMID: 21493818 - PMCID: PMC3339257 - DOI: 10.1161/CIRCGENETICS.110.958470
McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R
Targeted nanoagents for the detection of cancers.
Mol Oncol. 2010;4(6):511-28 - PMID: 20851695 - PMCID: PMC2981649 - DOI: 10.1016/j.molonc.2010.08.003
Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R
MRI of a Novel Murine Working Heart Transplant Model
Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535 - DOI: 10.1161/CIRCHEARTFAILURE.109.852707
Jaffer FA, Tung CH, Gerszten RE, Weissleder R
In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe
Arterioscler Thromb Vasc Biol. 2002;22:1929-35 - PMID: 12426227 - DOI: 10.1161/01.atv.0000033089.56970.2d
Simoncini T, Rabkin E, Liao J
Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells.
Arterioscler Thromb Vasc Biol. 2003;23:198-203 - PMID: 12588759 - DOI: 10.1161/01.atv.0000053846.71621.93
Jaffer FA, Libby P, Weissleder R
Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228 - DOI: 10.1161/ATVBAHA.108.165530
Swirski FK, Weissleder R, Pittet MJ
Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - DOI: 10.1161/ATVBAHA.108.180521
Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R
Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors.
Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086
Deguchi JO, Yamazaki H, Aikawa E, Aikawa M
Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages.
Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051 - DOI: 10.1161/ATVBAHA.109.194043
Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA
Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis. Novel Detection by Dual-Target Fluorescence Molecular Imaging.
Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475 - DOI: 10.1161/ATVBAHA.110.206342
Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R
Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography-Computed Tomography.
Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - DOI: 10.1161/ATVBAHA.110.221499
Swirski FK
The spatial and developmental relationships in the macrophage family.
Arterioscler Thromb Vasc Biol. 2011;31(7):1517-22 - PMID: 21677294 - PMCID: PMC3117206 - DOI: 10.1161/ATVBAHA.110.221150
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