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Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF
A genomic and evolutionary approach reveals non-genetic drug resistance in malaria.
Genome Biol. 2014;15(11):511 - PMID: 25395010 - PMCID: PMC4272547 - DOI: 10.1186/PREACCEPT-1067113631444973
Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS
Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers.
Genome Biol. 2008;9(7):R108 - PMID: 18611264 - PMCID: PMC2530866 - DOI: 10.1186/gb-2008-9-7-r108
Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ, Richardson PG, Hideshima T, Anderson KC
Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma.
Leukemia. 2013;28(3):680-9 - PMID: 23913134 - PMCID: PMC4165599 - DOI: 10.1038/leu.2013.231
Hideshima T, Mazitschek R, Santo L, Mimura N, Gorgun G, Richardson PG, Raje N, Anderson KC
Induction of differential apoptotic pathways in multiple myeloma cells by class selective histone deacetylase inhibitors.
Leukemia. 2013;28(2):457-60 - PMID: 24150220 - PMCID: PMC4405100 - DOI: 10.1038/leu.2013.301
Eda H, Santo L, Cirstea DD, Yee AJ, Scullen TA, Nemani N, Mishima Y, Waterman PR, Arastu-Kapur S, Evans E, Singh J, Kirk CJ, Westlin WF, Raje NS
A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
Leukemia. 2014;28(9):1892-901 - PMID: 24518207 - DOI: 10.1038/leu.2014.69
Touhami M, Fauvel-Lafève F, Da Silva N, Chomienne C, Legrand C
Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells.
Leukemia. 1997;11(12):2137-42 - PMID: 9447832 - DOI: 10.1038/sj.leu.2400866
Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG
Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines.
Leukemia. 1994;8(12):2083-94 - PMID: 7528856
DaSilva N, Hu ZB, Ma W, Rosnet O, Birnbaum D, Drexler HG
Expression of the FLT3 gene in human leukemia-lymphoma cell lines.
Leukemia. 1994;8(5):885-8 - PMID: 8182945
Chen W, Sun CC, Chen S, Meynard D, Babitt JL, Lin HY
A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.
Haematologica. 2012;98(2):296-304 - PMID: 22875629 - PMCID: PMC3561439 - DOI: 10.3324/haematol.2012.070136
Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX
Stress-induced hematopoietic failure in the absence of immediate early response gene X-1.
Haematologica. 2013;99(2):282-91 - PMID: 24056813 - PMCID: PMC3912958 - DOI: 10.3324/haematol.2013.092452
Chung J*, Shao H*, Reiner T, Issadore D, Weissleder R, Lee H
Cell Sorting: Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells
Adv Healthc Mater. 2012;1(4):432-6 - PMID: 23184773 - PMCID: PMC3508764 - DOI: 10.1002/adhm.201200046
Issadore D*, Chung HJ*, Chung J, Budin G, Weissleder R*, Lee H*
μHall Chip for Sensitive Detection of Bacteria
Adv Healthc Mater. 2013;2(9):1224-8 - PMID: 23495188 - PMCID: PMC4340655 - DOI: 10.1002/adhm.201200380
Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R*
Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040 - DOI: 10.1002/adhm.201300672
Hong S, Carlson J, Lee H, Weissleder R
Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking.
Adv Healthc Mater. 2015;5(4):421-426 - PMID: 26688173 - PMCID: PMC4811597 - DOI: 10.1002/adhm.201500780
Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R
Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis.
Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693 - PMCID: PMC4044727 - DOI: 10.1093/brain/awn004
Polasek M, Fuchs BC, Uppal R, Schühle DT, Alford JK, Loving GS, Yamada S, Wei L, Lauwers GY, Guimaraes AR, Tanabe KK, Caravan P
Molecular MR Imaging of Liver Fibrosis: A Feasibility Study using Rat and Mouse Models.
J Hepatol. 2012;57(3):549-55 - PMID: 22634342 - PMCID: PMC3423553 - DOI: 10.1016/j.jhep.2012.04.035
Ladapo JA, Jaffer FA, Weinstein MC, Froelicher ES
Projected Cost-effectiveness of Smoking Cessation Interventions in Patients Hospitalized With Myocardial Infarction.
Arch Intern Med. 2011;171(1):39-45 - PMID: 21220659 - DOI: 10.1001/archinternmed.2010.479
Bogdanov A, Weissleder R
The development of in vivo imaging systems to study gene expression.
Trends Biotechnol. 1998;16(1):5-10 - PMID: 9470227 - DOI: 10.1016/S0167-7799(97)01150-5
Zhao M, Weissleder R
Intracellular cargo delivery using tat peptide and derivatives
Med Res Rev. 2004;24:1-12 - PMID: 14595670 - DOI: 10.1002/med.10056
Pittet M, Zippelius A, Valmori D, Speiser D, Cerottini J, Romero P
Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.
Trends Immunol. 2002;23:325-8 - PMID: 12103339 - DOI: 10.1016/s1471-4906(02)02244-5
Squadrito ML, Etzrodt M, De Palma M, Pittet MJ
MicroRNA-mediated control of macrophages and its implications for cancer.
Trends Immunol. 2013;34(7):350-9 - PMID: 23498847 - PMCID: PMC3700601 - DOI: 10.1016/j.it.2013.02.003
Hwang WL, Marciscano AE, Niemierko A, Kim DW, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Loeffler JS, Oh KS, Shih HA, Larvie M
Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade.
Neuro Oncol. 2015;18(6):863-72 - PMID: 26597949 - PMCID: PMC4864259 - DOI: 10.1093/neuonc/nov285
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors.
Trends Pharmacol Sci. 2008;29(3):159-65 - PMID: 18262662 - DOI: 10.1016/j.tips.2007.12.002
Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM
Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.
Ann Rheum Dis. 2013;73(6):1170-1175 - PMID: 23716066 - PMCID: PMC3815491 - DOI: 10.1136/annrheumdis-2012-203202
Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D
Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy.
J Am Soc Nephrol. 2008;20(3):489-94 - PMID: 19118149 - PMCID: PMC2653682 - DOI: 10.1681/ASN.2008050503
Izawa A*, Ueno T*, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R
Importance of donor- and recipient-derived selectins in cardiac allograft rejection.
J Am Soc Nephrol. 2007;18(11):2929-36 - PMID: 17928506 - DOI: 10.1681/ASN.2006111261
Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R
Divergent role of donor dendritic cells in rejection versus tolerance of allografts.
J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678 - DOI: 10.1681/ASN.2008040377
Xia Y, Babitt JL, Bouley R, Zhang Y, Silva ND, Chen S, Zhuang Z, Samad TA, Brenner GJ, Anderson JL, Hong CC, Schneyer AL, Brown D, Lin HY
Dragon Enhances BMP Signaling and Increases Transepithelial Resistance in Kidney Epithelial Cells.
J Am Soc Nephrol. 2010;21(4):666-77 - PMID: 20167703 - PMCID: PMC2844302 - DOI: 10.1681/ASN.2009050511
Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D
Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration.
J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035 - DOI: 10.1681/ASN.2009121267
Breton S, Marsolais M, Lapointe JY, Laprade R
Cell volume increases of physiologic amplitude activate basolateral K and CI conductances in the rabbit proximal convoluted tubule.
J Am Soc Nephrol. 1996;7(10):2072-87 - PMID: 8915967 - DOI: 10.1681/ASN.V7102072
Breton S, Brown D
Cold-induced microtubule disruption and relocalization of membrane proteins in kidney epithelial cells.
J Am Soc Nephrol. 1998;9(2):155-66 - PMID: 9527391 - DOI: 10.1681/ASN.V92155
Sabolić I, Herak-Kramberger CM, Breton S, Brown D
Na/K-ATPase in intercalated cells along the rat nephron revealed by antigen retrieval.
J Am Soc Nephrol. 1999;10(5):913-22 - PMID: 10232676 - DOI: 10.1681/ASN.V105913
Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Desch
Pendrin regulation in mouse kidney primarily is chloride-dependent.
J Am Soc Nephrol. 2006;17(8):2153-63 - PMID: 16825334 - DOI: 10.1681/ASN.2005101054
Brown D, Wagner CA
Molecular Mechanisms of Acid-Base Sensing by the Kidney.
J Am Soc Nephrol. 2012;23(5):774-80 - PMID: 22362904 - PMCID: PMC3338302 - DOI: 10.1681/ASN.2012010029
Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA
Aquaporin 2 Promotes Cell Migration and Epithelial Morphogenesis.
J Am Soc Nephrol. 2012;23(9):1506-17 - PMID: 22859853 - PMCID: PMC3431417 - DOI: 10.1681/ASN.2012010079
Babitt JL, Lin HY
Mechanisms of Anemia in CKD.
J Am Soc Nephrol. 2012;23(10):1631-4 - PMID: 22935483 - PMCID: PMC3458456 - DOI: 10.1681/ASN.2011111078
Brown D, Jenny Lu HA
Aquaporin-2 Inhibitors: Fishing in the Chemical Pool.
J Am Soc Nephrol. 2013;24(5):685-6 - PMID: 23599384 - DOI: 10.1681/ASN.2013030243
Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D,
Defining Kidney Biology to Understand Renal Disease.
Clin J Am Soc Nephrol. 2013;9(4):809-11 - PMID: 24370769 - PMCID: PMC3974369 - DOI: 10.2215/CJN.10851013
Soehnlein O, Swirski FK
Hypercholesterolemia links hematopoiesis with atherosclerosis.
Trends Endocrin Met. 2012;24(3):129-136 - PMID: 23228326 - PMCID: PMC4302393 - DOI: 10.1016/j.tem.2012.10.008
Corradini E, Babitt JL, Lin HY
The RGM/DRAGON family of BMP co-receptors.
Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994 - DOI: 10.1016/j.cytogfr.2009.10.008
Hilderbrand SA, Weissleder R
Near-infrared fluorescence: application to in vivo molecular imaging.
Curr Opin Chem Biol. 2009;14:1-9 - PMID: 19879798 - DOI: 10.1016/j.cbpa.2009.09.029
Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D
Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells.
eLife. 2014;3:e04631 - PMID: 25407682 - PMCID: PMC4270084 - DOI: 10.7554/eLife.04631
Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
eLife. 2015;4:ePub - PMID: 25998054 - PMCID: PMC4441007 - DOI: 10.7554/eLife.05920
Naxerova K, Elledge SJ
Taking the brakes off telomerase.
eLife. 2015;4:ePub - PMID: 26194808 - PMCID: PMC4507575 - DOI: 10.7554/eLife.09519
Jochems J, Boulden J, Lee BG, Blendy JA, Jarpe M, Mazitschek R, Van Duzer JH, Berton O
Antidepressant-Like Properties of Novel HDAC6 Selective Inhibitors with Improved Brain Bioavailability.
Neuropsychopharmacology. 2013;39(2):389-400 - PMID: 23954848 - PMCID: PMC3870780 - DOI: 10.1038/npp.2013.207
Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R
In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas
Cancer Res. 2004;64:273-8 - PMID: 14729634 - DOI: 10.1158/0008-5472.can-03-1123
Grimm J, Perez JM, Josephson L, Weissleder R
Novel nanosensors for rapid analysis of telomerase activity
Cancer Res. 2004;64:639-43 - PMID: 14744779 - DOI: 10.1158/0008-5472.can-03-2798
Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A Jr
Near-infrared fluorescent imaging of tumor apoptosis
Cancer Res. 2003;63:1936-42 - PMID: 12702586
Kircher MF, Allport, JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R
In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors
Cancer Res. 2003;63:6838-46 - PMID: 14583481
Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L
A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation
Cancer Res. 2003;63:8122-5 - PMID: 14678964
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