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Tanaka K, Albin MJ, Yuan X, Yamaura K, Habicht A, Murayama T, Grimm M, Waaga AM, Ueno T, Padera RF, Yagita H, Azuma M, Shin T, Blazar BR, Rothstein DM, Sayegh MH, Najafian N
PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.
J Immunol. 2007;179(8):5204-10 - PMID: 17911605 - PMCID: PMC2291549 - DOI: 10.4049/jimmunol.179.8.5204
Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N
TIM-3: a novel regulatory molecule of alloimmune activation.
J Immunol. 2010;185(10):5806-19 - PMID: 20956339 - PMCID: PMC3619947 - DOI: 10.4049/jimmunol.0903435
Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu MD, Wu J
Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells.
J Immunol. 2001;166(5):3130-42 - PMID: 11207265 - DOI: 10.4049/jimmunol.166.5.3130
Misaghi S, Garris CS, Sun Y, Nguyen A, Zhang J, Sebrell A, Senger K, Yan D, Lorenzo MN, Heldens S, Lee WP, Xu M, Wu J, DeForge L, Sai T, Dixit VM, Zarrin AA
Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells.
J Immunol. 2010;185(1):166-73 - PMID: 20511552 - DOI: 10.4049/jimmunol.1000515
Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R.
Optical Imaging of Spontaneous Breast Tumors Using Protease Sensing
Invest Radiol. 2005;(6):321-327 - PMID: 15905717 - DOI: 10.1097/01.rli.0000163797.23172.90
Frank H, Loewe R, Loewe C, Oberhuber G, Schwaighofer B, Huber K, Weissleder R
Efficacy of thrombolytic therapy in pulmonary embolism determined by MION-enhanced MRA: an experimental study in rabbits.
Invest Radiol. 1998;33(12):853-7 - PMID: 9851818 - DOI: 10.1097/00004424-199812000-00002
Cheng HC, Khan MA, Bogdanov A, Kwong K, Weissleder R
Relative blood volume measurements by magnetic resonance imaging facilitate detection of testicular torsion.
Invest Radiol. 1997;32(12):763-9 - PMID: 9406017 - DOI: 10.1097/00004424-199712000-00007
Schulze E, Ferrucci JT, Poss K, Lapointe L, Bogdanova A, Weissleder R
Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro.
Invest Radiol. 1995;30(10):604-10 - PMID: 8557500 - DOI: 10.1097/00004424-199510000-00006
Weissleder R, Bogdanov A, Frank H, Nossiff N, Bogdanova A, Schaffer BK, Brady T, Wittenberg J
AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy.
Invest Radiol. 1993;28(12):1083-9 - PMID: 8307710 - DOI: 10.1097/00004424-199312000-00001
Reimer P, Weissleder R, Nickeleit V, Brady TJ
Animal models for magnetic resonance imaging research of the liver.
Invest Radiol. 1992;27(5):390-3 - PMID: 1582824 - DOI: 10.1097/00004424-199205000-00014
GrĂ¼ber G, Marshansky V
New insights into structure-function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0).
Bioessays. 2008;30(11-12):1096-109 - PMID: 18937357 - DOI: 10.1002/bies.20827
Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK
N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption.
Mol Cell Biol. 2006;26(11):4185-200 - PMID: 16705170 - PMCID: PMC1489079 - DOI: 10.1128/MCB.01055-05
Gabriely G, Wurdinger T, Kesari S, Esau C, Burchard J, Linsley P, Krichevsky A
MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators.
Mol Cell Biol. 2008;28(17):5369-80 - PMID: 18591254 - PMCID: PMC2519720 - DOI: 10.1128/MCB.00479-08
Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes.
Mol Cell Biol. 2010;31(2):351-64 - PMID: 21059868 - PMCID: PMC3019975 - DOI: 10.1128/MCB.00259-10
Shah K, Breakefield XO
HSV Amplicon Vectors for Cancer Therapy.
Curr Gene Ther. 2006;6(3):361-70 - PMID: 16787187 - DOI: 10.2174/156652306777592063
Babitt JL, Lin HY
Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD.
Am J Kidney Dis. 2010;55(4):726-41 - PMID: 20189278 - PMCID: PMC2905036 - DOI: 10.1053/j.ajkd.2009.12.030
Shayakul C, Breton S, Brown D, Alper SL
Gene therapy of inherited renal tubular disease.
Am J Kidney Dis. 1999;34(2):374-9 - PMID: 10430991 - DOI: 10.1016/s0272-6386(99)70372-0
Gultepe E, Reynoso FJ, Jhaveri A, Kulkarni P, Nagesha D, Ferris C, Harisinghani M, Campbell RB, Sridhar S
Monitoring of magnetic targeting to tumor vasculature through MRI and biodistribution.
Nanomedicine (Lond). 2010;5(8):1173-82 - PMID: 21039195 - DOI: 10.2217/nnm.10.84
King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA
E2F3 plays an essential role in cardiac development and function.
Cell Cycle. 2008;7(23):3775-80 - PMID: 19029823 - PMCID: PMC2723769 - DOI: 10.4161/cc.7.23.7240
Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U
Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization.
Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355 - DOI: 10.1016/j.gie.2006.02.048
Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R
Molecular imaging of myocardial infarction.
J Mol Cell Cardiol. 2006;41:921-933 - PMID: 17067633 - DOI: 10.1016/j.yjmcc.2006.09.008
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.
RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893 - DOI: 10.1261/rna.2300406
Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bunemann M
Kinetics of G-protein-coupled receptor signals in intact cells.
Brit J Pharmacol. 2008;153 Suppl 1:S125-32 - PMID: 18193071 - PMCID: PMC2268076 - DOI: 10.1038/sj.bjp.0707656
Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R
Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin
Eur J Cancer. 2000;36:675-81 - PMID: 10738134 - DOI: 10.1016/s0959-8049(99)00335-4
Weissleder R, Cheng HC, Marecos E, Kwong K, Bogdanov A
Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions.
Eur J Cancer. 1998;34(9):1448-54 - PMID: 9849430 - DOI: 10.1016/s0959-8049(98)00195-6
Stieber F, Grether U, Mazitschek R, Soric N, Giannis A, Waldmann H
Multistep solid-phase synthesis of an antibiotic and receptor tyrosine kinase inhibitors using the traceless phenylhydrazide linker.
Chemistry. 2003;9(14):3282-91 - PMID: 12866072 - DOI: 10.1002/chem.200304821
Speiser D, Lienard D, Pittet M, Batard P, Rimoldi D, Guillaume P, Cerottini J, Romero P
In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells.
Eur J Immunol. 2002;32:731-41 - PMID: 11870617 - DOI: 10.1002/1521-4141(200203)32:3<731::AID-IMMU731>3.0.CO;2-H
Speiser D, Migliaccio M, Pittet M, Valmori D, Lienard D, Lejeune F, Reichenbach P, Guillaume P, Lascher I, Cerottini J, Romero P
Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells.
Eur J Immunol. 2001;31:459-66 - PMID: 11180110 - DOI: 10.1002/1521-4141(200102)31:2<459::aid-immu459>3.0.co;2-y
Speiser D, Valmori D, Rimoldi D, Pittet M, Lienard D, Cerundolo V, MacDonald H, Cerottini J, Romero P
CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
Swirski F, Gajewska B, Robbins C, D'Sa A, Johnson J, Pouladi M, Inman M, Stampfli M
Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta, breaks established inhalation tolerance.
Eur J Immunol. 2004;34(9):2375-86 - PMID: 15307170 - DOI: 10.1002/eji.200425012
Galande A, Weissleder R, Tung CH.
An Effective Method of On-Resin Disulfide Bond Formation in Peptides
J Comb Chem. 2005;7:174-177 - PMID: 15762743 - DOI: 10.1021/cc049839r
Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L
Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation.
J Comb Chem. 2009;12(1):57-64 - PMID: 19928910 - PMCID: PMC2877490 - DOI: 10.1021/cc900141b
Weissleder R, Marfil A, Martinez HR, Rangel-Guerra RA
Limb girdle type muscular dystrophy associated with a Wolff-Parkinson-White syndrome.
J Neurol Neurosurg Psych. 1987;50(4):500-1 - PMID: 3585373 - PMCID: PMC1031899 - DOI: 10.1136/jnnp.50.4.500
Rabkin-Aikawa E, Aikawa M, Farber M, Kratz J, Garcia-Cardena G, Kouchoukos N, Mitchell M, Jonas R, Schoen F
Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site.
J Thorac Cardiovasc Surg. 2004;128:552-61 - PMID: 15457156 - DOI: 10.1016/j.jtcvs.2004.04.016
Wagner CA, L
A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse.
Pflug Arch Eur J Phy. 2003;446(5):623-32 - PMID: 12748863 - DOI: 10.1007/s00424-003-1082-3
Swirski F, Gajewska B, Alvarez D, Ritz S, Cundall M, Cates E, Coyle A, Gutierrez-Ramos J, Inman M, Jordana M, Stampfli M
Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice.
Clin Exp Allergy. 2002;32:411-21 - PMID: 11940072 - DOI: 10.1046/j.1365-2222.2002.01291.x
Pham W, Lai WF, Weissleder R, Tung CH
High efficiency synthesis of a bioconjugatable near-infrared fluorochrome
Bioconjug Chem. 2003;14:1048-51 - PMID: 13129411 - DOI: 10.1021/bc034070h
Moon, WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH
Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate
Bioconjug Chem. 2003;14:539-45 - PMID: 12757377 - DOI: 10.1021/bc0340114
Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L
Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells
Bioconjug Chem. 2003;14:1115-21 - PMID: 14624624 - DOI: 10.1021/bc034123v
Zhao M, Kircher MF, Josephson L, Weissleder R
Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake
Bioconjug Chem. 2002;13:840-4 - PMID: 12121140 - DOI: 10.1021/bc0255236
Wunderbaldinger P, Josephson L, Weissleder R
Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles
Bioconjug Chem. 2002;13:264-8 - PMID: 11906263 - DOI: 10.1021/bc015563u
Lin Y, Weissleder R, Tung CH
Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation
Bioconjug Chem. 2002;13:605-10 - PMID: 12009952 - DOI: 10.1021/bc0155723
Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A Jr
Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture
Bioconjug Chem. 2002;13:122-7 - PMID: 11792187 - DOI: 10.1021/bc0155521
Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R
Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes
Bioconjug Chem. 2002;13:554-60 - PMID: 12009946 - DOI: 10.1021/bc015555d
Hogemann D, Ntziachristos V, Josephson L, Weissleder R
High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes
Bioconjug Chem. 2002;13:116-21 - PMID: 11792186 - DOI: 10.1021/bc015549h
Weissleder R, Bogdanov A Jr, Tung CH, Weinmann HJ
Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging
Bioconjug Chem. 2001;12:213-9 - PMID: 11312682 - DOI: 10.1021/bc000091p
Hogemann D, Josephson L, Weissleder R, Basilion JP
Improvement of MRI probes to allow efficient detection of gene expression
Bioconjug Chem. 2000;11:941-6 - PMID: 11087345 - DOI: 10.1021/bc000079x
Bhorade R, Weissleder R, Nakakoshi T, Moore A, Tung CH
Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide
Bioconjug Chem. 2000;11:301-5 - PMID: 10821645 - DOI: 10.1021/bc990168d
Tung CH, Bredow S, Mahmood U, Weissleder R
Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging
Bioconjug Chem. 1999;10:892-6 - PMID: 10502358 - DOI: 10.1021/bc990052h
Josephson L, Tung CH, Moore A, Weissleder R
High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates
Bioconjug Chem. 1999;10:186-91 - PMID: 10077466 - DOI: 10.1021/bc980125h
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