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McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022
Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V
Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model.
Neuroimage. 2009;44(4):1304-11 - PMID: 19041402 - DOI: 10.1016/j.neuroimage.2008.10.038
Yuan H, Luo J, Weissleder R, Cantley L, Josephson L
Wortmannin-C20 Conjugates Generate Wortmannin.
J Med Chem. 2006;49(2):740-747 - PMID: 16420059 - DOI: 10.1021/jm050699p
Galande A, Hilderbrand S, Weissleder R, Tung CH.
Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core
J Med Chem. 2006;49(15):4715-20 - PMID: 16854078 - DOI: 10.1021/jm051001a
Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L.
Multivalent effects of RGD peptides obtained by nanoparticle display
J Med Chem. 2006;49(20):6087-6093
Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L
Slow Self-Activation Enhances The Potency of Viridin Prodrugs.
J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427 - DOI: 10.1021/jm800374f
Estiu G, Greenberg E, Harrison C, Kwiatkowski N, Mazitschek R, Bradner J, Wiest O
Structural origin of selectivity in class II-selective histone deacetylase inhibitors.
J Med Chem. 2008;51:2898-906 - PMID: 18412327 - DOI: 10.1021/jm7015254
Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J
Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum.
J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731 - DOI: 10.1021/jm801654y
Kissau L, Stahl P, Mazitschek R, Giannis A, Waldmann H
Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold.
J Med Chem. 2003;46(14):2917-31 - PMID: 12825933 - DOI: 10.1021/jm0307943
Lewin M, Bredow S, Sergeyev N, Marecos E, Bogdanov A Jr, Weissleder R
In vivo assessment of vascular endothelial growth factor-induced angiogenesis
Int J Cancer. 1999;83:798-802 - PMID: 10597197 - DOI: 10.1002/(sici)1097-0215(19991210)83:6<798::aid-ijc16>3.0.co;2-w
Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U.
A novel mouse model for segmental orthotopic colon cancer
Int J Cancer. 2005;117(3):335-9 - PMID: 15900588 - DOI: 10.1002/ijc.21185
Figueiredo JL, Alencar H, Weissleder R, Mahmood U
Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer.
Int J Cancer. 2006;118(11):2672-7 - PMID: 16380983 - DOI: 10.1002/ijc.21713
Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U
Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment.
Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072 - DOI: 10.1002/ijc.22995
Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP
MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo.
Int J Cancer. 2004;112(6):986-93 - PMID: 15386354 - DOI: 10.1002/ijc.20509
Lacy-Hulbert A*, Ueno T*, Ito T, Jurewicz M, Izawa A, Smith RN, Chase CM, Tanaka K, Fiorina P, Russell PS, Auchincloss H, Sayegh MH, Hynes RO, Abdi R
Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection.
Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - DOI: 10.1111/j.1600-6143.2007.01757.x
Yamaura K, Boenisch O, Watanabe T, Ueno T, Vanguri V, Yang J, Tanaka K, Guleria I, Borst J, Zhai Y, Kupiec-Weglinski JW, Najafian N
Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells.
Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922 - DOI: 10.1111/j.1600-6143.2010.03089.x
Jurewicz M, Ueno T, Azzi J, Tanaka K, Murayama T, Yang S, Sayegh MH, Niimi M, Abdi R
Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity.
Am J Transplant. 2010;11(2):348-355 - PMID: 21182586 - DOI: 10.1111/j.1600-6143.2010.03360.x
Zaharchuk G, Mandeville JB, Bogdanov AA Jr, Weissleder R, Rosen BR, Marota JJ
Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension
Stroke. 1999;30:2197-204; discussion 2204-5 - PMID: 10512929 - DOI: 10.1161/01.str.30.10.2197
Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R
Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model
Stroke. 2004;35:952-7 - PMID: 14988578 - DOI: 10.1161/01.STR.0000120308.21946.5D
Law B, Curino A, Bugge TH, Weissleder R, Tung CH
Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter.
Chem Biol. 2004;11(1):99-106 - PMID: 15112999 - DOI: 10.1016/j.chembiol.2003.12.017
Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L
Covalent Reactions of Wortmannin under Physiological Conditions.
Chem Biol. 2007;14(3):321-8 - PMID: 17379147 - DOI: 10.1016/j.chembiol.2007.02.007
Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P
A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages.
Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040 - DOI: 10.1016/j.chembiol.2007.10.005
Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN
A robust small-molecule microarray platform for screening cell lysates.
Chem Biol. 2006;13(5):493-504 - PMID: 16720270 - DOI: 10.1016/j.chembiol.2006.03.004
Kozloff KM, Weissleder R, Mahmood U
Non-Invasive Optical Detection of Bone Mineral.
J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196 - DOI: 10.1359/jbmr.070504
Tsourkas A, Newton G, Perez JM, Basilion J, Weissleder R.
Detection of Peroxidase-Mediated Dityrosine Formation with Enhanced Yellow Fluorescent Protein
Anal Chem. 2005;77:2862-2867 - PMID: 15859603 - DOI: 10.1021/ac0480747
Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L
Multiparameter Magnetic Relaxation Switch Assays.
Anal Chem. 2007;(79) 23:8863-9 - PMID: 17983206 - DOI: 10.1021/ac701976p
Koh I, Hong R, Weissleder R, Josephson L
Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions.
Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647 - DOI: 10.1021/ac802717c
Im H, Lesuffleur A, Lindquist NC, Oh SH
Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing.
Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634 - DOI: 10.1021/ac802276x
Sosnovik DE, Nahrendorf M, Weissleder R
Targeted imaging of myocardial damage.
Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115
Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O
Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology
Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357
Sosnovik DE, Nahrendorf M, Weissleder R
Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.
Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7
Nahrendorf M, Sosnovik DE, Weissleder R
MR-optical imaging of cardiovascular molecular targets.
Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2
Groen A, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison T
A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.
J Cell Sci. 2008;121(Pt 14):2293-300 - PMID: 18559893 - PMCID: PMC2902979 - DOI: 10.1242/jcs.024018
Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819 - DOI: 10.1242/jcs.046813
Tran AD, Marmo TP, Salam AA, Che S, Finkelstein E, Kabarriti R, Xenias HS, Mazitschek R, Hubbert C, Kawaguchi Y, Sheetz MP, Yao TP, Bulinski JC
HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions.
J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687 - DOI: 10.1242/jcs.03431
Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ
Multimodality Cardiovascular Molecular Imaging, Part I
Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549 - DOI: 10.1161/CIRCIMAGING.108.824359
Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ
Multimodality Cardiovascular Molecular Imaging, Part II
Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054 - DOI: 10.1161/CIRCIMAGING.108.839092
Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ
Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium
Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045 - DOI: 10.1161/CIRCIMAGING.108.815050
Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A
Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure.
Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779
Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L
Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia.
Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678
Libby P, DiCarli M, Weissleder R
The Vascular Biology of Atherosclerosis and Imaging Targets.
J Nucl Med. 2010;51 Suppl 1:33S-37S - PMID: 20395349 - DOI: 10.2967/jnumed.109.069633
Kramer CM, Sinusas AJ, Sosnovik DE, French BA, Bengel FM
Multimodality Imaging of Myocardial Injury and Remodeling.
J Nucl Med. 2010;51 Suppl 1:107S-121S - PMID: 20395347 - PMCID: PMC3078824 - DOI: 10.2967/jnumed.109.068221
Bogdanov AA, Callahan RJ, Wilkinson RA, Martin C, Cameron JA, Fischman AJ, Brady TJ, Weissleder R
Synthetic copolymer kit for radionuclide blood-pool imaging.
J Nucl Med. 1994;35(11):1880-6 - PMID: 7965173
Nahrendorf M, Wiesmann F, Hiller K, Han H, Hu K, Waller C, Ruff J, Haase A, Ertl G, Bauer W
In vivo assessment of cardiac remodeling after myocardial infarction in rats by cine-magnetic resonance imaging.
J Cardiovasc Magn Reson. 2001;2(3):171-80 - PMID: 11545114 - DOI: 10.3109/10976640009146565
Sosnovik DE, Caravan P
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents
J Cardiovasc Magn Reson. 2009;2:87-94
Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ
Diffusion MR tractography of the heart.
J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805 - DOI: 10.1186/1532-429X-11-47
Law B, Weissleder R, Tung CH
Peptide-based Biomaterials for Protease-Enhanced Drug Delivery
Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747 - DOI: 10.1021/bm050920f
Law B, Tung CH
Structural modification of protease inducible preprogrammed nanofiber precursor.
Biomacromolecules. 2008;9:421-5 - PMID: 18177006 - DOI: 10.1021/bm7012026
Yoshida S, Shimada M, Ueno T, Kitamura Y, Matsuzaki S, Nishikubo S, Nagae M, Nakanishi K, Murata J, Yoshino M
Successful endoscopic submucosal dissection of duodenal cancer.
Endoscopy. 2008;40 Suppl 2:E132-3 - PMID: 18633861 - DOI: 10.1055/s-2007-995685
Yoshida S, Shimada M, Ueno T, Kato A, Yoshino M
Latex hand glove: a safe and convenient device for the endoscopic removal of foreign bodies.
Endoscopy. 2008;40 Suppl 2:E195-6 - PMID: 18709613 - DOI: 10.1055/s-2008-1077420
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