Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis.
Sci Transl Med. 2020;12(568):ePub - PMID: 33148623 - PMCID: PMC7818516 - DOI: 10.1126/scitranslmed.aay2104
Prosaposin mediates inflammation in atherosclerosis.
Sci Transl Med. 2021;13(584):eabe1433 - PMID: 33692130 - PMCID: PMC8209679 - DOI: 10.1126/scitranslmed.abe1433
Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer.
Sci Transl Med. 2021;13(594):eabd1346 - PMID: 34011627 - PMCID: PMC8325152 - DOI: 10.1126/scitranslmed.abd1346
A rapid assay provides on-site quantification
of tetrahydrocannabinol in oral fluid
Sci Transl Med. 2021;13(616):eabe2352 - PMID: 34669441 - PMCID: PMC9126021 - DOI: 10.1126/scitranslmed.abe2352 - Cover
Leveraging technology to address current and future world issues.
Magnetic sensors for protease assays
Angew Chem Int Ed Engl. 2003;42:1375-8 - PMID: 12671972 - DOI: 10.1002/anie.200390352
An azulene dimer as a near-infrared quencher
Angew Chem Int Ed Engl. 2002;41:3659-62, 3519 - PMID: 12370922 - DOI: 10.1002/1521-3773(20021004)41:19<3659::AID-ANIE3659>3.0.CO;2-Q
Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities
Angew Chem Int Ed Engl. 2004;43(18):2395-2399 - PMID: 15114571 - DOI: 10.1002/anie.200352998
Sensitive NMR Sensors Detect Antibodies to Influenza.
Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198 - DOI: 10.1002/anie.200800069
Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System.
Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069 - DOI: 10.1002/anie.200901791
Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition.
Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075 - DOI: 10.1002/anie.200903233
Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells.
Angew Chem Int Ed Engl. 2010;19 (49):2869-2872 - PMID: 20306505 - PMCID: PMC3433403 - DOI: 10.1002/anie.200906120
Synthesis and In Vivo Imaging of a (18) F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method.
Angew Chem Int Ed Engl. 2011;50(8):1922-5 - PMID: 21328671 - PMCID: PMC3471140 - DOI: 10.1002/anie.201006579
Highly magnetic core-shell nanoparticles with a unique magnetization mechanism.
Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859 - DOI: 10.1002/anie.201100101
Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification.
Angew Chem Int Ed Engl. 2011;50(40):9378-81 - PMID: 21948435 - PMCID: PMC3187564 - DOI: 10.1002/anie.201103273
Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers.
Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171 - DOI: 10.1002/anie.201105670
Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging.
Angew Chem Int Ed Engl. 2011;51(4):920-2 - PMID: 22162316 - PMCID: PMC3304098 - DOI: 10.1002/anie.201104389
Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors.
Angew Chem Int Ed Engl. 2004;43(2):224-8 - PMID: 14695616 - DOI: 10.1002/anie.200352582
Small molecules as inhibitors of cyclin-dependent kinases.
Angew Chem Int Ed Engl. 2003;42(19):2122-38 - PMID: 12761741 - DOI: 10.1002/anie.200200540
Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors.
Angew Chem Int Ed Engl. 2002;41(7):1174-8 - PMID: 12491250 - DOI: 10.1002/1521-3773(20020402)41:7<1174::aid-anie1174>3.0.co;2-v
Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2.
Angew Chem Int Ed Engl. 2002;41(24):4757-61 - PMID: 12481350 - DOI: 10.1002/anie.200290040
IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids.
Angew Chem Int Ed Engl. 2002;41(21):4059-61 - PMID: 12412081 - DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R
A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung.
Angew Chem Int Ed Engl. 2001;40(19):3672-3674 - PMID: 11592218 - DOI: 10.1002/1521-3773(20011001)40:19<3672::aid-anie3672>3.0.co;2-y
Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin.
Angew Chem Int Ed Engl. 1999;38(21):3228-3231 - PMID: 10556911 - DOI: 10.1002/(sici)1521-3773(19991102)38:21<3228::aid-anie3228>3.0.co;2-8
Synthesis of [(18) F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging.
Angew Chem Int Ed Engl. 2012;51(19):4603-6 - PMID: 22473535 - PMCID: PMC3343182 - DOI: 10.1002/anie.201107957
Bioorthogonal Imaging of Aurora Kinase A in Live Cells.
Angew Chem Int Ed Engl. 2012;51(27):6598-603 - PMID: 22644700 - PMCID: PMC3523717 - DOI: 10.1002/anie.201200994
A Magnetic Gram Stain for Bacterial Detection.
Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380 - DOI: 10.1002/anie.201202982
BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes.
Angew Chem Int Ed Engl. 2013;52(27):6917-6920 - PMID: 23712730 - PMCID: PMC3875324 - DOI: 10.1002/anie.201301100
Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells
Angew Chem Int Ed Engl. 2013;52(40):10593-7 - PMID: 23960025 - PMCID: PMC3856564 - DOI: 10.1002/anie.201304096
Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging.
Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131 - DOI: 10.1002/anie.201403890
Magnetic Nanosensors for the Detection of Oligonucleotide Sequences.
Angew Chem Int Ed Engl. 2001;40(17):3204-3206 - PMID: 29712059 - DOI: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H
A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9.
Angew Chem Int Ed Engl. 2019;58(19):6285-6289 - PMID: 30834641 - PMCID: PMC7067309 - DOI: 10.1002/anie.201900788
Ultra-fast cycling for multiplexed cellular fluorescence imaging.
Angew Chem Int Ed Engl. 2020;59(17):6839-6846 - PMID: 32004403 - DOI: 10.1002/anie.201915153
Magnetic Silica-Coated Fluorescent Microspheres (MagSiGlow) for Simultaneous Detection of Tumor-Associated Proteins.
Angew Chem Int Ed Engl. 2024;:e202318870 - PMID: 38578432 - DOI: 10.1002/anie.202318870
Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media
J Am Chem Soc. 2003;125:10192-3 - PMID: 12926940 - DOI: 10.1021/ja036409g
DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents
J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860 - DOI: 10.1021/ja017773n
Molecular Dynamics of Ion-Chelate Complexes Attached to Starburst(TM) Dendrimers
J Am Chem Soc. 1996;118:7774-7782
Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors.
J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703 - DOI: 10.1021/ja038471j
Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation.
Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity.
Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition.
Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins.
J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626 - DOI: 10.1021/ja202451t
Total synthesis and biological evaluation of the nakijiquinones.
J Am Chem Soc. 2001;123(47):11586-93 - PMID: 11716712 - DOI: 10.1021/ja011413i
Single Reporter for Targeted Multimodal in Vivo Imaging.
Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cell.
J Am Chem Soc. 2012;134(45):18499-18502 - PMID: 23092113 - PMCID: PMC3498844 - DOI: 10.1021/ja307689w
Covalent Modulators of the Vacuolar ATPase.
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator.
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis.
Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage.
J Am Chem Soc. 2018;140(10):3603-3612 - PMID: 29384666 - PMCID: PMC5857921 - DOI: 10.1021/jacs.7b11217
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes.
J Am Chem Soc. 2020;142(45):19132-19141 - PMID: 33119297 - PMCID: PMC7662912 - DOI: 10.1021/jacs.0c07922