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Carlson JCT, Hogan C, Ivkovic A
Case 5-2019: A Woman with Delusional Thinking and Paresthesia of the Right Hand. Reply.
N Engl J Med. 2019;380(21):2082 - PMID: 31116941 - DOI: 10.1056/NEJMc1903635
Hogan C, Little BP, Carlson JCT, Freudenreich O, Ivkovic A, Baron JM
Case 5-2019: A 48-Year-Old Woman with Delusional Thinking and Paresthesia of the Right Hand.
N Engl J Med. 2019;380(7):665-674 - PMID: 30763197 - DOI: 10.1056/NEJMcpc1807495
Swirski FK, Nahrendorf M
Reply to 'Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies'.
Nat Rev Immunol. 2019;19(1):65 - PMID: 30552386 - DOI: 10.1038/s41577-018-0099-y
Hovestadt V, Smith KS, Bihannic L, Filbin MG, Shaw ML, Baumgartner A, DeWitt JC, Groves A, Mayr L, Weisman HR, Richman AR, Shore ME, Goumnerova L, Rosencrance C, Carter RA, Phoenix TN, Hadley JL, Tong Y, Houston J, Ashmun RA, DeCuypere M, Sharma T, Flasch D, Silkov A, Ligon KL, Pomeroy SL, Rivera MN, Rozenblatt-Rosen O, Rusert JM, Wechsler-Reya RJ, Li XN, Peyrl A, Gojo J, Kirchhofer D, Lötsch D, Czech T, Dorfer C, Haberler C, Geyeregger R, Halfmann A, Gawad C, Easton J, Pfister SM, Regev A, Gajjar A, Orr BA, Slavc I, Robinson GW, Bernstein BE, Suvà ML, Northcott PA
Resolving medulloblastoma cellular architecture by single-cell genomics.
Nature. 2019;572(7767):74-79 - PMID: 31341285 - DOI: 10.1038/s41586-019-1434-6
McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK
Sleep modulates haematopoiesis and protects against atherosclerosis
Nature. 2019;566(7744):383-387 - PMID: 30760925 - PMCID: PMC6442744 - DOI: 10.1038/s41586-019-0948-2
He S*, Kahles F*, Rattik S*, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK
Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease
Nature. 2019;566(7742):115-119 - PMID: 30700910 - PMCID: PMC6367023 - DOI: 10.1038/s41586-018-0849-9
Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà ML
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.
Cell. 2019;178(4):835-849.e21 - PMID: 31327527 - PMCID: PMC6703186 - DOI: 10.1016/j.cell.2019.06.024
van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.
Cell. 2019;176(6):1265-1281.e24 - PMID: 30827681 - PMCID: PMC6515904 - DOI: 10.1016/j.cell.2019.01.031
Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
Nat Med. 2019;25(8):1264-1269 - PMID: 31263286 - DOI: 10.1038/s41591-019-0493-4
Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.
Cell Stem Cell. 2019;:ePub - PMID: 31279774 - DOI: 10.1016/j.stem.2019.06.003
Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Crist C, Brack AS
Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress.
Cell Stem Cell. 2019;24(6):944-957.e5 - PMID: 31006621 - PMCID: PMC6597014 - DOI: 10.1016/j.stem.2019.03.020
Zilionis R*, Engblom C*, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ**, Klein AM**
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species.
Immunity. 2019;50(5):1317-1334.e10 - PMID: 30979687 - PMCID: PMC6620049 - DOI: 10.1016/j.immuni.2019.03.009
Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K
Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction.
Circulation. 2019;140(6):487-499 - PMID: 31170826 - PMCID: PMC6684855 - DOI: 10.1161/CIRCULATIONAHA.118.038820
RamÍrez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C
Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation.
Circulation. 2019;140(3):225-239 - PMID: 31154825 - DOI: 10.1161/CIRCULATIONAHA.118.038571
Hoyer FF, Nahrendorf M
Uremic Toxins Activate Macrophages.
Circulation. 2019;139(1):97-100 - PMID: 30592654 - PMCID: PMC6394415 - DOI: 10.1161/CIRCULATIONAHA.118.037308
Cruz Hernández JC, Bracko O, Kersbergen CJ, Muse V, Haft-Javaherian M, Berg M, Park L, Vinarcsik LK, Ivasyk I, Rivera DA, Kang Y, Cortes-Canteli M, Peyrounette M, Doyeux V, Smith A, Zhou J, Otte G, Beverly JD, Davenport E, Davit Y, Lin CP, Strickland S, Iadecola C, Lorthois S, Nishimura N, Schaffer CB
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.
Nat Neurosci. 2019;22(3):413-420 - PMID: 30742116 - PMCID: PMC6508667 - DOI: 10.1038/s41593-018-0329-4
Jain IH, Zazzeron L, Goldberger O, Marutani E, Wojtkiewicz GR, Ast T, Wang H, Schleifer G, Stepanova A, Brepoels K, Schoonjans L, Carmeliet P, Galkin A, Ichinose F, Zapol WM, Mootha VK
Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation.
Cell Metab. 2019;:ePub - PMID: 31402314 - DOI: 10.1016/j.cmet.2019.07.006
Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.
Sci Transl Med. 2019;11(506):ePub - PMID: 31434756 - DOI: 10.1126/scitranslmed.aaw7736
Hulsmans M, Nahrendorf M
Smad3 Cranks Up the Appetite of Infarct Macrophages.
Circ Res. 2019;125(1):71-73 - PMID: 31219739 - PMCID: PMC6588180 - DOI: 10.1161/CIRCRESAHA.119.315306
Courties G, Frodermann V, Honold L, Zheng Y, Herisson FE, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden D, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M
Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke.
Circ Res. 2019;124(9):1372-1385 - PMID: 30782088 - PMCID: PMC6483874 - DOI: 10.1161/CIRCRESAHA.118.314518
Rohde D, Nahrendorf M
Clonal and diverse: revisiting cardiac endothelial cells after myocardial infarction.
Eur Heart J. 2019;40(30):2521-2522 - PMID: 31162523 - PMCID: PMC6685322 - DOI: 10.1093/eurheartj/ehz375
Leuschner F, Nahrendorf M
Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction.
Eur Heart J. 2019;:ePub - PMID: 30945736 - DOI: 10.1093/eurheartj/ehz159
Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Santos Masson G, Tesmenitsky Y, Folco E, Gram H, Nahrendorf M, Swirski FK, Sukhova GK, Libby P
Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.
Eur Heart J. 2019;40(30):2482-2491 - PMID: 30698710 - PMCID: PMC6685323 - DOI: 10.1093/eurheartj/ehz008
Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK
Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.
J Exp Med. 2019;216(2):369-383 - PMID: 30670465 - PMCID: PMC6363430 - DOI: 10.1084/jem.20180722
Tawakol A, Osborne MT, Wang Y, Hammed B, Tung B, Patrich T, Oberfeld B, Ishai A, Shin LM, Nahrendorf M, Warner ET, Wasfy J, Fayad ZA, Koenen K, Ridker PM, Pitman RK, Armstrong KA
Stress-Associated Neurobiological Pathway Linking Socioeconomic Disparities to Cardiovascular Disease.
J Am Coll Cardiol. 2019;73(25):3243-3255 - PMID: 31248544 - DOI: 10.1016/j.jacc.2019.04.042
Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O
Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.
J Am Coll Cardiol. 2019;73(23):2990-3002 - PMID: 31196457 - DOI: 10.1016/j.jacc.2019.03.503
Choudhary A, Manna D, Maji B, Gangopadhyay SA, Cox KJ, Zhou Q, Law B, Mazitschek R
A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9.
Angew Chem Int Ed Engl. 2019;58(19):6285-6289 - PMID: 30834641 - DOI: 10.1002/anie.201900788
Huang CH, Park YI, Lin HY, Pathania D, Park KS, Avila-Wallace M, Castro CM, Weissleder R, Lee H
Compact and Filter-Free Luminescence Biosensor for Mobile <i>In-Vitro</i> Diagnoses.
ACS Nano. 2019;:ePub - PMID: 31461265 - DOI: 10.1021/acsnano.9b05634
Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA
Radiation-Induced Targeted Nanoparticle- Based Gene Delivery for Brain Tumor Therapy
ACS Nano. 2019;13(4):4028-4040 - PMID: 30916923 - DOI: 10.1021/acsnano.8b08177
Liu CL, Zhang X, Liu J, Wang Y, Sukhova GK, Wojtkiewicz GR, Liu T, Tang R, Achilefu S, Nahrendorf M, Libby P, Guo J, Zhang JY, Shi GP
Na+ - H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis.
Nat Commun. 2019;10(1):3978 - PMID: 31484936 - PMCID: PMC6726618 - DOI: 10.1038/s41467-019-11983-3
Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, Furman RR, Gnirke A, Wu CJ, Melnick AM, Meissner A, Bernstein BE, Abdel-Wahab O, Landau DA
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.
Nat Commun. 2019;10(1):1874 - PMID: 31015400 - PMCID: PMC6478836 - DOI: 10.1038/s41467-019-09645-5
Liu P, Zhao L, Pol J, Levesque S, Petrazzuolo A, Pfirschke C, Engblom C, Rickelt S, Yamazaki T, Iribarren K, Senovilla L, Bezu L, Vacchelli E, Sica V, Melis A, Martin T, Xia L, Yang H, Li Q, Chen J, Durand S, Aprahamian F, Lefevre D, Broutin S, Paci A, Bongers A, Minard-Colin V, Tartour E, Zitvogel L, Apetoh L, Ma Y, Pittet MJ, Kepp O, Kroemer G
Crizotinib-induced immunogenic cell death in non-small cell lung cancer.
Nat Commun. 2019;10(1):1486 - PMID: 30940805 - PMCID: PMC6445096 - DOI: 10.1038/s41467-019-09415-3
Wang CY, Xiao X, Bayer A, Xu Y, Dev S, Canali S, Nair AV, Masia R, Babitt JL
Ablation of hepatocyte Smad1, Smad5 and Smad8 causes severe tissue iron loading and liver fibrosis in mice.
Hepatology. 2019;:ePub - PMID: 31127639 - DOI: 10.1002/hep.30780
Ho M, Chen T, Liu J, Dowling P, Hideshima T, Zhang L, Morelli E, Camci-Unal G, Wu X, Tai YT, Wen K, Samur M, Schlossman RL, Mazitschek R, Kavanagh EL, Lindsay S, Harada T, McCann A, Anderson KC, O'Gorman P, Bianchi G
Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling.
Leukemia. 2019;:ePub - PMID: 31142847 - DOI: 10.1038/s41375-019-0493-x
Yassin M, Aqaqe N, Yassin AA, van Galen P, Kugler E, Bernstein BE, Koren-Michowitz M, Canaani J, Nagler A, Lechman ER, Dick JE, Wienholds E, Izraeli S, Milyavsky M
A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity.
Leukemia. 2019;33(8):2061-2077 - PMID: 30705411 - DOI: 10.1038/s41375-019-0386-z
Lee H, Castro CM
Thermophoretically enriched detection.
Nat Biomed Eng. 2019;3(3):163-164 - PMID: 30948812 - DOI: 10.1038/s41551-019-0364-9
Park SG, Xiao X, Min J, Mun CW, Jung HS, Giannini V, Weissleder R, Maier SA, Im H, Kim DH
Self‐Assembly of Nanoparticle‐Spiked Pillar Arrays for Plasmonic Biosensing
Adv Funct Mater. 2019;:ePub - DOI: 10.1002/adfm.201904257
Heyde A, Reiter JG, Naxerova K, Nowak MA
Consecutive seeding and transfer of genetic diversity in metastasis.
Proc Natl Acad Sci U S A. 2019;116(28):14129-14137 - PMID: 31239334 - PMCID: PMC6628640 - DOI: 10.1073/pnas.1819408116
Babitt JL
Ironing out pulmonary arterial hypertension.
Proc Natl Acad Sci U S A. 2019;116(26):12604-12606 - PMID: 31171658 - PMCID: PMC6601273 - DOI: 10.1073/pnas.1908298116
Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW
An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo.
Proc Natl Acad Sci U S A. 2019;116(24):11966-11971 - PMID: 31123149 - PMCID: PMC6575581 - DOI: 10.1073/pnas.1818434116
Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ
A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor
Proc Natl Acad Sci U S A. 2019;116(23):11444-11453 - PMID: 31101720 - PMCID: PMC6561274 - DOI: 10.1073/pnas.1702372116
Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK
Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.
Proc Natl Acad Sci U S A. 2019;116(22):10674-10680 - PMID: 31040208 - PMCID: PMC6561160 - DOI: 10.1073/pnas.1819889116
Morini E, Gao D, Montgomery CM, Salani M, Mazzasette C, Krussig TA, Swain B, Dietrich P, Narasimhan J, Gabbeta V, Dakka A, Hedrick J, Zhao X, Weetall M, Naryshkin NA, Wojtkiewicz GG, Ko CP, Talkowski ME, Dragatsis I, Slaugenhaupt SA
ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia.
Am J Hum Genet. 2019;104(4):638-650 - PMID: 30905397 - PMCID: PMC6451698 - DOI: 10.1016/j.ajhg.2019.02.009
Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Boerger EAS, Mc Causland FR, Eisenga MF, Singh K, Babitt JL, Kellum JA, Palevsky PM, Christov M, Waikar SS
Iron, Hepcidin, and Death in Human AKI.
J Am Soc Nephrol. 2019;30(3):493-504 - PMID: 30737269 - PMCID: PMC6405140 - DOI: 10.1681/ASN.2018100979
Bae SH, Jo A, Park JH, Lim CW, Choi Y, Oh J, Park JM, Kong T, Weissleder R, Lee H, Moon J
Bioassay for monitoring the anti-aging effect of cord blood treatment.
Theranostics. 2019;9(1):1-10 - PMID: 30662549 - PMCID: PMC6332798 - DOI: 10.7150/thno.30422
Ferder IC, Fung L, Ohguchi Y, Zhang X, Lassen KG, Capen D, Brown D, Xavier RJ, Wang N
Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.
PLoS Genet. 2019;15(5):e1008084 - PMID: 31059511 - PMCID: PMC6502318 - DOI: 10.1371/journal.pgen.1008084
Gyuris A, Navarrete-Perea J, Jo A, Cristea S, Zhou S, Fraser K, Wei Z, Krichevsky AM, Weissleder R, Lee H, Gygi SP, Charest A
Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity.
Cell Rep. 2019;27(13):3972-3987.e6 - PMID: 31242427 - PMCID: PMC6604862 - DOI: 10.1016/j.celrep.2019.05.089
Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS
c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.
Cell Rep. 2019;27(8):2304-2312.e6 - PMID: 31116977 - DOI: 10.1016/j.celrep.2019.04.090
Zaborowski MP, Lee K, Na YJ, Sammarco A, Zhang X, Iwanicki M, Cheah PS, Lin HY, Zinter M, Chou CY, Fulci G, Tannous BA, Lai CP, Birrer MJ, Weissleder R, Lee H, Breakefield XO
Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles.
Cell Rep. 2019;27(1):255-268.e6 - PMID: 30943406 - PMCID: PMC6528836 - DOI: 10.1016/j.celrep.2019.03.003
Chen J, Landegger LD, Sun Y, Ren J, Maimon N, Wu L, Ng MR, Chen JW, Zhang N, Zhao Y, Gao X, Fujita T, Roberge S, Huang P, Jain RK, Plotkin SR, Stankovic KM, Xu L
A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.
Nat Protoc. 2019;14(2):541-555 - PMID: 30617350 - PMCID: PMC6571021 - DOI: 10.1038/s41596-018-0105-7
Ippen FM, Alvarez-Breckenridge CA, Kuter BM, Fink AL, Bihun IV, Lastrapes M, Penson T, Schmidt SP, Wojtkiewicz GR, Ning J, Subramanian M, Giobbie-Hurder A, Martinez-Lage M, Carter SL, Cahill DP, Wakimoto H, Brastianos PK
The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in <i>PIK3CA</i>-Mutant Breast Cancer Brain Metastases.
Clin Cancer Res. 2019;25(11):3374-3383 - PMID: 30796030 - PMCID: PMC6685218 - DOI: 10.1158/1078-0432.CCR-18-3049
Mindur JE, Swirski FK
Growth Factors as Immunotherapeutic Targets in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2019;:ATVBAHA119311994 - PMID: 31092009 - PMCID: PMC6613384 - DOI: 10.1161/ATVBAHA.119.311994
Li A, Wu Y, Pulli B, Wojtkiewicz GR, Iwamoto Y, Wang C, Li JH, Ali M, Feng X, Yao Z, Chen JW
Myeloperoxidase Molecular MRI Reveals Synergistic Combination Therapy in Murine Experimental Autoimmune Neuroinflammation.
Radiology. 2019;:182492 - PMID: 31478802 - DOI: 10.1148/radiol.2019182492
Hoyer FF, Nahrendorf M
Interferon-ɣ regulates cardiac myeloid cells in myocardial infarction.
Cardiovasc Res. 2019;:ePub - PMID: 31161218 - DOI: 10.1093/cvr/cvz143
Stokes KL, Cortez-Retamozo V, Acosta J, Lauderback B, Robles-Oteiza C, Cicchini M, Pittet MJ, Feldser DM
Natural killer cells limit the clearance of senescent lung adenocarcinoma cells.
Oncogenesis. 2019;8(4):24 - PMID: 30936429 - PMCID: PMC6443683 - DOI: 10.1038/s41389-019-0133-3
Larkin M, Nathan DM, Bebu I, Krause-Steinrauf H, Herman WH, Higgins JM, Tiktin M, Cohen RM, Lund C, Bergenstal RM, Johnson M, Arends V, Research Group G
Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring.
Diabetes Technol Ther. 2019;:ePub - PMID: 31393176 - DOI: 10.1089/dia.2019.0202
Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre A, Nahrendorf M, Weissleder R
A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart.
Bioconjug Chem. 2019;30(3):733-740 - PMID: 30615425 - PMCID: PMC6483069 - DOI: 10.1021/acs.bioconjchem.8b00882
Battistone MA, Merkulova M, Park YJ, Peralta MA, Gombar F, Brown D, Breton S
Unraveling purinergic regulation in the epididymis: Activation of V-ATPase-dependent acidification by luminal ATP and adenosine.
J Physiol. 2019;597(7):1957-1973 - PMID: 30746715 - PMCID: PMC6441927 - DOI: 10.1113/JP277565 - Cover
Fagbami L, Deik AA, Herman JD, Singh K, Santos SA, Bopp S, Lukens AK, Clish CB, Wirth DF, Mazitschek R
The adaptive proline response in P. falciparum is independent of PfeIK1 and eIF2α signaling.
ACS Infect Dis. 2019;5(4):515-520 - PMID: 30773881 - PMCID: PMC6747701 - DOI: 10.1021/acsinfecdis.8b00363
Tan X, Patil R, Bartosik P, Runnels JM, Lin CP, Niedre M
In Vivo Flow Cytometry of Extremely Rare Circulating Cells.
Sci Rep. 2019;9(1):3366 - PMID: 30833671 - PMCID: PMC6399281 - DOI: 10.1038/s41598-019-40143-2
Kim B, Breton S
Androgens are essential for epithelial cell recovery after efferent duct ligation in the initial segment of the mouse epididymis.
Biol Reprod. 2019;:ePub - PMID: 31403160 - DOI: 10.1093/biolre/ioz152
Krasner CN, Castro C, Penson RT, Roche M, Matulonis UA, Morgan MA, Drescher C, Armstrong DK, Wolfe JK, Lee H, Supko JG, Seiden M, Birrer MJ, Dizon DS
Final report on serial phase II trials of all-intraperitoneal chemotherapy with or without bevacizumab for women with newly diagnosed, optimally cytoreduced carcinoma of Müllerian origin.
Gynecol Oncol. 2019;153(2):223-229 - PMID: 30765148 - DOI: 10.1016/j.ygyno.2019.02.004
Babitt JL, Sitara D
Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease.
Curr Opin Nephrol Hypertens. 2019;28(4):304-310 - PMID: 31145704 - PMCID: PMC6693648 - DOI: 10.1097/MNH.0000000000000514
Nair AV, Yanhong W, Paunescu TG, Bouley R, Brown D
Sex-dependent differences in water homeostasis in wild-type and V-ATPase B1-subunit deficient mice.
PLoS ONE. 2019;14(8):e0219940 - PMID: 31386675 - PMCID: PMC6684071 - DOI: 10.1371/journal.pone.0219940
Li R, Attari A, Prytyskach M, Garlin MA, Weissleder R, Miller MA
Single‐Cell Intravital Microscopy of Trastuzumab Quantifies Heterogeneous in vivo Kinetics
Cytometry A. 2019;:ePub - PMID: 31423731 - DOI: 10.1002/cyto.a.23872
Marshansky V, Hosokawa H, Merkulova M, Bakulina A, Dip PV, Thaker YR, Bjargava A, Tonra JR, Ausiello DA, Grüber G
Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design.
Curr Top Membr. 2019;83:77-106 - PMID: 31196611 - DOI: 10.1016/bs.ctm.2019.01.008
Zhao WN, Hylton NK, Wang J, Chindavong PS, Alural B, Kurtser I, Subramanian A, Mazitschek R, Perlis RH, Haggarty SJ
Activation of WNT and CREB signaling pathways in human neuronal cells in response to the Omega-3 fatty acid docosahexaenoic acid (DHA).
Mol Cell Neurosci. 2019;99:103386 - PMID: 31202891 - DOI: 10.1016/j.mcn.2019.06.006
Bassir SH, Garakani S, Wilk K, Aldawood ZA, Hou J, Yeh SA, Sfeir C, Lin CP, Intini G
Prx1 Expressing Cells Are Required for Periodontal Regeneration of the Mouse Incisor.
Front Physiol. 2019;10:591 - PMID: 31231227 - PMCID: PMC6558369 - DOI: 10.3389/fphys.2019.00591
Ahrens CC, Chiswick EL, Ravindra KC, Miller MA, Ramseier J, Isaacson KB, Lauffenburger DA, Griffith LG
Development and Application of the Metalloprotease Activity Multi-plexed Bead-based Immunoassay (MAMBI).
Biochemistry. 2019;:ePub - PMID: 31474112 - DOI: 10.1021/acs.biochem.9b00584
Patil R, Tan X, Bartosik P, Detappe A, Runnels JM, Ghobrial I, Lin CP, Niedre M
Fluorescence monitoring of rare circulating tumor cell and cluster dissemination in a multiple myeloma xenograft model in vivo.
J Biomed Opt. 2019;24(8):1-11 - PMID: 31456386 - DOI: 10.1117/1.JBO.24.8.085004
Breton S, Nair AV, Battistone MA
Epithelial dynamics in the epididymis: role in the maturation, protection, and storage of spermatozoa.
Andrology. 2019;7(5):631-643 - PMID: 31044554 - PMCID: PMC6688936 - DOI: 10.1111/andr.12632
Sullivan R, Légaré C, Lamontagne-Proulx J, Breton S, Soulet D
Revisiting structure/functions of the human epididymis.
Andrology. 2019;7(5):748-757 - PMID: 31033221 - DOI: 10.1111/andr.12633
Marquard AN, Carlson JCT, Weissleder R
Glass Chemistry to Analyze Human Cells under Adverse Conditions
ACS Omega. 2019;4:11515−11521 - PMID: 31460257 - PMCID: PMC6682085 - DOI: 10.1021/acsomega.9b01036 - Cover
Kordbacheh H, Baliyan V, Parakh A, Wojtkiewicz GR, Hedgire S, Harisinghani MG
Pictorial review on abdominal applications of ferumoxytol in MR imaging.
Abdom Radiol (NY). 2019;44(10):3273-3284 - PMID: 31378828 - DOI: 10.1007/s00261-019-02163-4
Chulroek T, Kordbacheh H, Wangcharoenrung D, Cattapan K, Heidari P, Harisinghani MG
Comparative accuracy of qualitative and quantitative 18F-FDG PET/CT analysis in detection of lymph node metastasis from anal cancer.
Abdom Radiol (NY). 2019;44(3):828-835 - PMID: 30694369 - DOI: 10.1007/s00261-019-01907-6
Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H
Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Nat Metab. 2019;1(5):519-531 - PMID: 31276102 - PMCID: PMC6609153 - DOI: 10.1038/s42255-019-0063-6
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