Reset

Tong T, Yang Z, Chen JW, Zhu J, Yao Z

Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma.
Oncotarget. 2015;6(31):32257-32265 - PMID: 26337080 - PMCID: PMC4741675 - DOI: 10.18632/oncotarget.4899

Hwang I, Oh H, Santo E, Kim DY, Chen JW, Bronson RT, Locasale JW, Na Y, Lee J, Reed S, Toth M, Yu WH, Muller FL, Paik J

FOXO protects against age-progressive axonal degeneration.
Aging Cell. 2017;17(1):ePub - PMID: 29178390 - PMCID: PMC5771393 - DOI: 10.1111/acel.12701

McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022

Wang C, Cheng D, Jalali Motlagh N, Kuellenberg EG, Wojtkiewicz GR, Schmidt SP, Stocker R, Chen JW

Highly Efficient Activatable MRI Probe to Sense Myeloperoxidase Activity.
J Med Chem. 2021;64(9):5874-5885 - PMID: 33945286 - PMCID: PMC8564765 - DOI: 10.1021/acs.jmedchem.1c00038

Zhang Y, Dong H, Seeburg DP, Wojtkiewicz GR, Waterman P, Pulli B, Forghani R, Ali M, Iwamoto Y, Swirski FK, Chen JW

Multimodal Molecular Imaging Demonstrates Myeloperoxidase Regulation of Matrix Metalloproteinase Activity in Neuroinflammation.
Mol Neurobiol. 2018;56(2):954-962 - PMID: 29808380 - PMCID: PMC6261713 - DOI: 10.1007/s12035-018-1137-2

Zeller MWG, Wang C, Keliher EJ, Wojtkiewicz GR, Aguirre A, Maresca K, Su C, Buckbinder L, Wang J, Nahrendorf M, Chen JW

Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction.
Int J Mol Sci. 2023;24(6):ePub - PMID: 36982778 - PMCID: PMC10057533 - DOI: 10.3390/ijms24065704

Ali M, Fulci G, Grigalavicius M, Pulli B, Li A, Wojtkiewicz GR, Wang C, Hsieh KL, Linnoila JJ, Theodossiou TA, Chen JW

Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy.
Neoplasia. 2022;26:100779 - PMID: 35247801 - PMCID: PMC8894277 - DOI: 10.1016/j.neo.2022.100779

Li JH, Forghani R, Bure L, Wojtkiewicz GR, Wu Y, Iwamoto Y, Ali M, Li A, Wang C, Jalali Motlagh N, Papadakis AI, Pusztaszeri MP, Spatz A, Curtin H, Cheng YS, Chen JW

Molecular immuno-imaging improves tumor detection in head and neck cancer.
FASEB J. 2022;36(1):e22092 - PMID: 34919761 - PMCID: PMC9584652 - DOI: 10.1096/fj.202100864R

Kim HJ, Wei Y, Wojtkiewicz GR, Lee JY, Moskowitz MA, Chen JW

Reducing myeloperoxidase activity decreases inflammation and increases cellular protection in ischemic stroke.
J Cereb Blood Flow Metab. 2018;39(9):1864-1877 - PMID: 29673284 - PMCID: PMC6727136 - DOI: 10.1177/0271678X18771978

Forghani R, Kim HJ, Wojtkiewicz GR, Bure L, Wu Y, Hayase M, Wei Y, Zheng Y, Moskowitz MA, Chen JW

Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke.
J Cereb Blood Flow Metab. 2014;35(3):485-93 - PMID: 25515211 - PMCID: PMC4348390 - DOI: 10.1038/jcbfm.2014.222

Petrozziello T, Motlagh NJ, Monsanto RZB, Lei D, Murcar MG, Penney EB, Bragg DC, Fernandez-Cerado C, Legarda GP, Sy M, Muñoz E, Ang MC, Diesta CCE, Zhang C, Tanzi RE, Qureshi IA, Chen JW, Sadri-Vakili G

Targeting Myeloperoxidase to Reduce Neuroinflammation in X-Linked Dystonia Parkinsonism.
CNS Neurosci Ther. 2024;30(11):e70109 - PMID: 39500625 - PMCID: PMC11537767 - DOI: 10.1111/cns.70109

Jalali Motlagh N, Wang C, Kuellenberg EG, Wojtkiewicz GR, Schmidt S, Chen JW

D-Mannose Slows Glioma Growth by Modulating Myeloperoxidase Activity.
Cancers (Basel). 2021;13(24):ePub - PMID: 34944979 - PMCID: PMC8699108 - DOI: 10.3390/cancers13246360

Badr CE, da Hora CC, Kirov AB, Tabet E, Amante R, Maksoud S, Nibbs AE, Fitzsimons E, Boukhali M, Chen JW, Chiu NHL, Nakano I, Haas W, Mazitschek R, Tannous BA

Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation.
ACS Chem Biol. 2020;15(6):1445-1454 - PMID: 32338864 - PMCID: PMC7995447 - DOI: 10.1021/acschembio.0c00104

Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA

Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging.
Sci Rep. 2015;5:17220 - PMID: 26610702 - PMCID: PMC4661695 - DOI: 10.1038/srep17220

Abou Haidar E, Prabhakar S, Geffrey AL, Mahamdeh M, Tomeh T, Breyne K, Roumieh E, Gurevich M, Soberman RJ, Wojtkiewicz GR, Chen JW, Han JS, Stemmer-Rachamimov A, Breakefield XO

AAV hamartin gene therapy in a stochastic, cerebral mouse model of tuberous sclerosis type 1.
Mol Ther Methods Clin Dev. 2025;33(3):101556 - PMID: 40932991 - PMCID: PMC12419009 - DOI: 10.1016/j.omtm.2025.101556

Kim H, Wei Y, Lee JY, Wu Y, Zheng Y, Moskowitz MA, Chen JW

Myeloperoxidase inhibition increases neurogenesis after ischemic stroke.
J Pharmacol Exp Ther. 2016;359(2):262-272 - PMID: 27550713 - PMCID: PMC5074486 - DOI: 10.1124/jpet.116.235127

Li A, Wu Y, Linnoila J, Pulli B, Wang C, Zeller M, Ali M, Lewandrowski GK, Li J, Tricot B, Keliher E, Wojtkiewicz GR, Fulci G, Feng X, Tannous BA, Yao Z, Chen JW

Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models.
Cancer Immunol Immunther. 2016;65(12):1545-1554 - PMID: 27722909 - PMCID: PMC5101144 - DOI: 10.1007/s00262-016-1911-9

Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, Wojtkiewicz G, Linnoila JJ, Chen JW

Measuring myeloperoxidase activity in biological samples.
PLoS ONE. 2013;8(7):e67976 - PMID: 23861842 - PMCID: PMC3702519 - DOI: 10.1371/journal.pone.0067976

Atkinson W*, Forghani R*, Wojtkiewicz GR, Pulli B, Iwamoto Y, Ueno T, Waterman P, Truelove J, Oklu R, Chen JW

Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice
PLoS ONE. 2012;7(3):e33671 - PMID: 22457780 - PMCID: PMC3310075 - DOI: 10.1371/journal.pone.0033671

Yoon BC, Pomerantz SR, Mercaldo ND, Goyal S, L'Italien EM, Lev MH, Buch KA, Buchbinder BR, Chen JW, Conklin J, Gupta R, Hunter GJ, Kamalian SC, Kelly HR, Rapalino O, Rincon SP, Romero JM, He J, Schaefer PW, Do S, González RG

Incorporating algorithmic uncertainty into a clinical machine deep learning algorithm for urgent head CTs.
PLoS ONE. 2023;18(3):e0281900 - PMID: 36913348 - PMCID: PMC10010506 - DOI: 10.1371/journal.pone.0281900

Prabhakar S, Goto J, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO

Stochastic model of tsc1 lesions in mouse brain.
PLoS ONE. 2013;8(5):e64224 - PMID: 23696872 - PMCID: PMC3655945 - DOI: 10.1371/journal.pone.0064224

Mehan WA, González RG, Buchbinder BR, Chen JW, Copen WA, Gupta R, Hirsch JA, Hunter GJ, Hunter S, Johnson JM, Kelly HR, Larvie M, Lev MH, Pomerantz SR, Rapalino O, Rincon S, Romero JM, Schaefer PW, Shah V

Optimal Brain MRI Protocol for New Neurological Complaint.
PLoS ONE. 2014;9(10):e110803 - PMID: 25343371 - PMCID: PMC4208779 - DOI: 10.1371/journal.pone.0110803

Hsieh LC, Chen JW, Wang LY, Tsang YM, Shueng PW, Liao LJ, Lo WC, Lin YC, Tseng CF, Kuo YS, Jhuang JY, Tien HJ, Juan HF, Hsieh CH

Predicting the severity and prognosis of trismus after intensity-modulated radiation therapy for oral cancer patients by magnetic resonance imaging.
PLoS ONE. 2014;9(3):e92561 - PMID: 24658376 - PMCID: PMC3962418 - DOI: 10.1371/journal.pone.0092561

Chen JW, Pham W, Weissleder R, Bogdanov A Jr

Human myeloperoxidase: A potential target for molecular MR imaging in atherosclerosis.
Magn Reson Med. 2004;52(5):1021-8 - PMID: 15508166 - DOI: 10.1002/mrm.20270

Pulli B, Chen JW

Imaging Neuroinflammation - from Bench to Bedside.
J Clin Cell Immunol. 2014;5:ePub - PMID: 25525560 - PMCID: PMC4266918 - DOI: 10.4172/2155-9899.1000226

J.W. Chen, F.P. Auteri, D.E. Budil, R.L. Belford, R.B. Clarkson

Use of EPR to Investigate Rotational Dynamics of MRI Paramagnetic Contrast Agents
J Phys Chem B. 1994;98:13452

J.W. Chen, R.B. Clarkson, R.L. Belford

Rotational Dynamics of MRI Paramagnetic Contrast Agents in Viscous Media
J Phys Chem B. 1996;100:8093-8100

J.W. Chen, R.L. Belford, R.B. Clarkson

Second-Sphere and Outer-Sphere Proton Relaxation of Paramagnetic Contrast Agents
J Phys Chem B. 1998;102:2117-2130

Lartey FM, Ahn GO, Ali R, Rosenblum S, Miao Z, Arksey N, Shen B, Colomer MV, Rafat M, Liu H, Alejandre-Alcazar MA, Chen JW, Palmer T, Chin FT, Guzman R, Loo BW, Graves E

The Relationship Between Serial [(18) F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice.
Mol Imaging Biol. 2014;16(6):821-9 - PMID: 24865401 - PMCID: PMC4237703 - DOI: 10.1007/s11307-014-0745-0

Querol Sans M*, Chen JW*, Weissleder R, Bogdanov AA

Myeloperoxidase Activity Imaging Using (67)Ga Labeled Substrate.
Mol Imaging Biol. 2005;7(6):403-10 - PMID: 16292477 - DOI: 10.1007/s11307-005-0020-5

Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F

Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections.
Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450 - DOI: 10.1017/S1431927609090813

Kevin Li-Chun H, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW

Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis.
J Neuroimmunol. 2015;287:36-42 - PMID: 26439960 - PMCID: PMC4595933 - DOI: 10.1016/j.jneuroim.2015.08.006

Shen S, Ding W, Ahmed S, Hu R, Opalacz A, Roth S, You Z, Wojtkiewicz GR, Lim G, Chen L, Mao J, Chen JW, Zhang Y

Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions.
Pain Med. 2018;19(4):686-692 - PMID: 29177411 - PMCID: PMC6659016 - DOI: 10.1093/pm/pnx267

Parsi S, Zhu C, Motlagh NJ, Kim D, Küllenberg EG, Kim HH, Gillani RL, Chen JW

Basic Science of Neuroinflammation and Involvement of the Inflammatory Response in Disorders of the Nervous System.
Magn Reson Imaging Clin N Am. 2024;32(2):375-384 - PMID: 38555147 - PMCID: PMC10987041 - DOI: 10.1016/j.mric.2024.01.003

Oklu R, Deipolyi AR, Wicky S, Ergul E, Deik AA, Chen JW, Hirsch JA, Wojtkiewicz GR, Clish CB

Identification of small compound biomarkers of pituitary adenoma: a bilateral inferior petrosal sinus sampling study.
J Neurointerv Surg. 2013;6(7):541-6 - PMID: 24005126 - DOI: 10.1136/neurintsurg-2013-010821

González RG, Copen WA, Schaefer PW, Lev MH, Pomerantz SR, Rapalino O, Chen JW, Hunter GJ, Romero JM, Buchbinder BR, Larvie M, Hirsch JA, Gupta R

The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach.
J Neurointerv Surg. 2013;5 Suppl 1:i7-i12 - PMID: 23493340 - PMCID: PMC3623036 - DOI: 10.1136/neurintsurg-2013-010715

Liang JS, Lee SP, Pulli B, Chen JW, Kao SC, Tsang YM, Hsieh KL

Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study.
Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405 - DOI: 10.1016/j.pedneo.2015.10.003

Chen J, Wasserman B

Vulnerable plaque imaging.
Neuroimag Clin N Am.. 2005;15:609-21, xi - PMID: 16360592 - DOI: 10.1016/j.nic.2005.08.005

Khan MA, Chang J, Song Y, Shetty AC, Nguyen T, Waters DN, Chowdhury DD, Simms E, Chan A, Tseng HW, Lam C, Patel P, Tran LT, Chen J, Wang JH, Nugent K, Ballew M, Lemtiri-Chlieh G, Carrieri FA, Malek R, Wang H, Thielman NRJ, Li K, Park RJ, Hwang WL, Zheng L, Gabrielson K, Tran PT, Lafargue A

Twist1 overexpression models an aggressive subtype of pancreatic ductal adenocarcinoma in vivo.
Lab Anim (NY). 2026;:ePub - PMID: 42174151 - DOI: 10.1038/s41684-026-01729-2

Bogdanov AA Jr, Chen JW, Kang HW, Weissleder R.

Magnetic resonance signal amplification probes
Ernst Schering Res Found Workshop. 2005;49:147-57 - PMID: 15524215 - DOI: 10.1007/3-540-26809-x_8

Petrozziello T, Motlagh NJ, Monsanto RZB, Lei D, Murcar MG, Penney EB, Bragg DC, Fernandez-Cerado C, Legarda GP, Sy M, Muñoz E, Ang MC, Diesta CCE, Zhang C, Tanzi RE, Qureshi IA, Chen JW, Sadri-Vakili G

Targeting myeloperoxidase to reduce neuroinflammation in X-linked dystonia parkinsonism.
medRxiv. 2024;:ePub - PMID: 38978657 - PMCID: PMC11230314 - DOI: 10.1101/2024.06.25.24309481

Yin Z, Wu L, Zhang Y, Sun Y, Chen JW, Subudhi S, Ho W, Lee GY, Wang A, Gao X, Ren J, Zhu C, Zhang N, Ferraro GB, Muzikansky A, Zhang L, Stemmer-Rachamimov A, Mao J, Plotkin SR, Xu L

Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain.
bioRxiv. 2023;:ePub - PMID: 36798353 - PMCID: PMC9934519 - DOI: 10.1101/2023.02.06.527377

Ali M, Pulli B, Chen JW

Molecular imaging of macrophage enzyme activity in cardiac inflammation.
Curr Cardiovasc Imaging Rep. 2014;7(4):9258 - PMID: 24729833 - PMCID: PMC3979571 - DOI: 10.1007/s12410-014-9258-0

Linnoila J, Pulli B, Armangué T, Planagumà J, Narsimhan R, Schob S, Zeller MWG, Dalmau J, Chen J

Mouse model of anti-NMDA receptor post-herpes simplex encephalitis.
Neurol Neuroimmunol Neuroinflamm. 2018;6(2):e529 - PMID: 30697582 - PMCID: PMC6340334 - DOI: 10.1212/NXI.0000000000000529
94 CSV HTML