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Weissleder R, Lee H
Automated molecular-image cytometry and analysis in modern oncology
Nature Review Materials. 2020;:ePub - DOI: 10.1038/s41578-020-0180-6
Swirski FK
Platelets have a dangerous hold over immune cells in cardiovascular disease.
Nature. 2020;577(7790):323-324 - PMID: 31937950 - DOI: 10.1038/d41586-019-03732-9
Christodoulou C, Spencer JA, Yeh SA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Guo G, Seyedhassantehrani N, Esipova TV, Vinogradov SA, Rudzinskas S, Zhang Y, Perkins AS, Orkin SH, Calogero RA, Schroeder T, Lin CP, Camargo FD
Live-animal imaging of native haematopoietic stem and progenitor cells.
Nature. 2020;578(7794):278-283 - PMID: 32025033 - PMCID: PMC7021587 - DOI: 10.1038/s41586-020-1971-z
ENCODE Project Consortium, Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z
Expanded encyclopaedias of DNA elements in the human and mouse genomes.
Nature. 2020;583(7818):699-710 - PMID: 32728249 - PMCID: PMC7410828 - DOI: 10.1038/s41586-020-2493-4
ENCODE Project Consortium, Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM
Perspectives on ENCODE.
Nature. 2020;583(7818):693-698 - PMID: 32728248 - PMCID: PMC7410827 - DOI: 10.1038/s41586-020-2449-8
Johnstone SE, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, Chen JH, Zou LS, Drier Y, Hecht V, Shoresh N, Selig MK, Lareau CA, Iyer S, Nguyen SC, Joyce EF, Hacohen N, Irizarry RA, Zhang B, Aryee MJ, Bernstein BE
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer.
Cell. 2020;182(6):1474-1489.e23 - PMID: 32841603 - PMCID: PMC7575124 - DOI: 10.1016/j.cell.2020.07.030
Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.
Nat Biotechnol. 2020;38(10):1174-1183 - PMID: 32855547 - PMCID: PMC7740072 - DOI: 10.1038/s41587-020-0659-0
Millar DG, Ramjiawan RR, Kawaguchi K, Gupta N, Chen J, Zhang S, Nojiri T, Ho WW, Aoki S, Jung K, Chen I, Shi F, Heather JM, Shigeta K, Morton LT, Sepulveda S, Wan L, Joseph R, Minogue E, Khatri A, Bardia A, Ellisen LW, Corcoran RB, Hata AN, Pai SI, Jain RK, Fukumura D, Duda DG, Cobbold M
Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy.
Nat Biotechnol. 2020;38(4):420-425 - PMID: 32042168 - PMCID: PMC7456461 - DOI: 10.1038/s41587-019-0404-8
Herrmann K, Schwaiger M, Lewis JS, Solomon SB, McNeil BJ, Baumann M, Gambhir SS, Hricak H, Weissleder R
Radiotheranostics: a roadmap for future development
Lancet Oncol. 2020;21(3):e146–56 - PMID: 32135118 - PMCID: PMC7367151 - DOI: 10.1016/S1470-2045(19)30821-6 - Cover
Naxerova K
Clonal competition in a confined space.
Nat Genet. 2020;52(6):553-554 - PMID: 32424354 - DOI: 10.1038/s41588-020-0638-x
Reiter JG, Hung WT, Lee IH, Nagpal S, Giunta P, Degner S, Liu G, Wassenaar ECE, Jeck WR, Taylor MS, Farahani AA, Marble HD, Knott S, Kranenburg O, Lennerz JK, Naxerova K
Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases.
Nat Genet. 2020;52(7):692-700 - PMID: 32451459 - PMCID: PMC7343611 - DOI: 10.1038/s41588-020-0633-2
Kato S, Weng QY, Insco ML, Chen KY, Muralidhar S, Pozniak J, Diaz JMS, Drier Y, Nguyen N, Lo JA, van Rooijen E, Kemeny LV, Zhan Y, Feng Y, Silkworth W, Powell CT, Liau BB, Xiong Y, Jin J, Newton-Bishop J, Zon LI, Bernstein BE, Fisher DE
Gain-of-function genetic alterations of G9a drive oncogenesis.
Cancer Discov. 2020;10(7):980-997 - PMID: 32269030 - PMCID: PMC7334057 - DOI: 10.1158/2159-8290.CD-19-0532
Yang KS, Ciprani D, O'Shea A, Liss A, Yang R, Fletcher-Mercaldo S, Mino-Kenudson M, Castillo CF, Weissleder R
Extracellular Vesicle Analysis Allows for Identification of Invasive IPMN
Gastroenterology. 2020;160(4):1345-1358.e11 - PMID: 33301777 - PMCID: PMC7956058 - DOI: 10.1053/j.gastro.2020.11.046
Senders ML, Meerwaldt AE, van Leent MMT, Sanchez-Gaytan BL, van de Voort JC, Toner YC, Maier A, Klein ED, Sullivan NAT, Sofias AM, Groenen H, Faries C, Oosterwijk RS, van Leeuwen EM, Fay F, Chepurko E, Reiner T, Duivenvoorden R, Zangi L, Dijkhuizen RM, Hak S, Swirski FK, Nahrendorf M, Pérez-Medina C, Teunissen AJP, Fayad ZA, Calcagno C, Strijkers GJ, Mulder WJM
Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging.
Nat Nanotechnol. 2020;15(5):398-405 - PMID: 32313216 - PMCID: PMC7416336 - DOI: 10.1038/s41565-020-0642-4
Leuschner F, Nahrendorf M
Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction.
Eur Heart J. 2020;41(9):989-994 - PMID: 30945736 - PMCID: PMC7778432 - DOI: 10.1093/eurheartj/ehz159
Swirski FK
ESC William Harvey Lecture on Basic Science 2020.
Eur Heart J. 2020;41(46):4373-4374 - PMID: 33349865 - DOI: 10.1093/eurheartj/ehaa766
Hoyer FF, Zhang X, Coppin E, Vasamsetti SB, Modugu G, Schloss MJ, Rohde D, McAlpine CS, Iwamoto Y, Libby P, Naxerova K, Swirski FK, Dutta P, Nahrendorf M
Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes.
Circulation. 2020;142(3):244-258 - PMID: 32316750 - PMCID: PMC7375017 - DOI: 10.1161/CIRCULATIONAHA.120.046038
Xiao L, Salem JE, Clauss S, Hanley A, Bapat A, Hulsmans M, Iwamoto Y, Wojtkiewicz G, Cetinbas M, Schloss MJ, Tedeschi J, Lebrun-Vignes B, Lundby A, Sadreyev RI, Moslehi JJ, Nahrendorf M, Ellinor PT, Milan DJ
Ibrutinib-Mediated Atrial Fibrillation Due to Inhibition of CSK.
Circulation. 2020;142(25):2443-2455 - PMID: 33092403 - PMCID: PMC9661397 - DOI: 10.1161/CIRCULATIONAHA.120.049210
Weissleder R, Pittet MJ
The expanding landscape of inflammatory cells affecting cancer therapy
Nat Biomed Eng. 2020;4(5):489-498 - PMID: 32203281 - PMCID: PMC7405944 - DOI: 10.1038/s41551-020-0524-y
Krohn-Grimberghe M, Mitchell MJ, Schloss MJ, Khan OF, Courties G, Guimaraes PPG, Rohde D, Cremer S, Kowalski PS, Sun Y, Tan M, Webster J, Wang K, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Nayar R, Frodermann V, Hulsmans M, Chung A, Hoyer FF, Swirski FK, Langer R, Anderson DG, Nahrendorf M
Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche.
Nat Biomed Eng. 2020;4(11):1076-1089 - PMID: 33020600 - PMCID: PMC7655681 - DOI: 10.1038/s41551-020-00623-7
Cheong J, Yu H, Lee CY, Lee JU, Choi HJ, Lee JH, Lee H, Cheon J
Fast detection of SARS-CoV-2 RNA via the integration of plasmonic thermocycling and fluorescence detection in a portable device.
Nat Biomed Eng. 2020;4(12):1159-1167 - PMID: 33273713 - PMCID: PMC8202505 - DOI: 10.1038/s41551-020-00654-0
Wang CY, Xu Y, Traeger L, Dogan DY, Xiao X, Steinbicker AU, Babitt JL
Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
Blood. 2020;135(6):453-456 - PMID: 31800957 - PMCID: PMC7005366 - DOI: 10.1182/blood.2019002620
Park SY, Matte A, Jung Y, Ryu J, Wilson AB, Han EYA, Liu M, Carbone C, Melisi D, Nagasawa T, Locascio JJ, Lin CP, Silberstein LE, De Franceschi L
Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversible by blood transfusion.
Blood. 2020;135(23):2071-2084 - PMID: 31990287 - PMCID: PMC7273832 - DOI: 10.1182/blood.2019002227
Al-Samkari H, Karp Leaf RS, Dzik WH, Carlson JC, Fogerty AE, Waheed A, Goodarzi K, Bendapudi P, Bornikova L, Gupta S, Leaf D, Kuter DJ, Rosovsky RP
COVID and Coagulation: Bleeding and Thrombotic Manifestations of SARS-CoV2 Infection.
Blood. 2020;136(4):489-500 - PMID: 32492712 - PMCID: PMC7378457 - DOI: 10.1182/blood.2020006520
Cremer S, Schloss MJ, Vinegoni C, Foy BH, Zhang S, Rohde D, Hulsmans M, Fumene Feruglio P, Schmidt S, Wojtkiewicz G, Higgins JM, Weissleder R, Swirski FK, Nahrendorf M
Diminished Reactive Hematopoiesis and Cardiac Inflammation in a Mouse Model of Recurrent Myocardial Infarction.
J Am Coll Cardiol. 2020;75(8):901-915 - PMID: 32130926 - PMCID: PMC7254576 - DOI: 10.1016/j.jacc.2019.12.056
Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, Bernstein BE, Lane AA
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity.
Nat Commun. 2020;11(1):1406 - PMID: 32179749 - PMCID: PMC7076002 - DOI: 10.1038/s41467-020-15221-z
Boivin G, Faget J, Ancey PB, Gkasti A, Mussard J, Engblom C, Pfirschke C, Contat C, Pascual J, Vazquez J, Bendriss-Vermare N, Caux C, Vozenin MC, Pittet MJ, Gunzer M, Meylan E
Durable and controlled depletion of neutrophils in mice.
Nat Commun. 2020;11(1):2762 - PMID: 32488020 - PMCID: PMC7265525 - DOI: 10.1038/s41467-020-16596-9
Luthria G, Li R, Wang S, Prytyskach M, Kohler RH, Lauffenburger DA, Mitchison TJ, Weissleder R, Miller MA
In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells
Nat Commun. 2020;11:3521 - PMID: 32665556 - PMCID: PMC7360550 - DOI: 10.1038/s41467-020-17147-y
Javed N, Farjoun Y, Fennell TJ, Epstein CB, Bernstein BE, Shoresh N
Detecting sample swaps in diverse NGS data types using linkage disequilibrium.
Nat Commun. 2020;11(1):3697 - PMID: 32728101 - PMCID: PMC7391710 - DOI: 10.1038/s41467-020-17453-5
Wang Y, Cao T, Ko J, Shen Y, Zong W, Sheng K, Cao W, Sun S, Cai L, Zhou YL, Zhang XX, Zong C, Weissleder R, Weitz D
Dissolvable Polyacrylamide Beads for High-Throughput Droplet DNA Barcoding.
Adv Sci. 2020;7(8):1903463 - PMID: 32328429 - PMCID: PMC7175265 - DOI: 10.1002/advs.201903463
Weissleder R, Lee H, Ko J, Pittet MJ
COVID-19 diagnostics in context
Sci Transl Med. 2020;12(546):eabc1931 - PMID: 32493791 - DOI: 10.1126/scitranslmed.abc1931
Min J*, Chin LK*, Oh J, Landeros C, Vinegoni C, Lee J, Lee SJ, Park JY, Liu AQ, Castro CM, Lee H, Im H, Weissleder R
CytoPAN—Portable cellular analyses for rapid point-of-care cancer diagnosis
Sci Transl Med. 2020;12:eaaz9746 - PMID: 32759277 - PMCID: PMC8217912 - DOI: 10.1126/scitranslmed.aaz9746
Panizzi P, Krohn-Grimberghe M, Keliher E, Ye YX, Grune J, Frodermann V, Sun Y, Muse CG, Bushey K, Iwamoto Y, van Leent MMT, Meerwaldt A, Toner YC, Munitz J, Maier A, Soultanidis G, Calcagno C, Pérez-Medina C, Carlucci G, Riddell KP, Barney S, Horne G, Anderson B, Maddur-Appajaiah A, Verhamme IM, Bock PE, Wojtkiewicz GR, Courties G, Swirski FK, Church WR, Walz PH, Tillson DM, Mulder WJM, Nahrendorf M
Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis.
Sci Transl Med. 2020;12(568):ePub - PMID: 33148623 - PMCID: PMC7818516 - DOI: 10.1126/scitranslmed.aay2104
Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R
Ultra-fast cycling for multiplexed cellular fluorescence imaging.
Angew Chem Int Ed Engl. 2020;59(17):6839-6846 - PMID: 32004403 - DOI: 10.1002/anie.201915153
Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT*, Mikula H*
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes.
J Am Chem Soc. 2020;142(45):19132-19141 - PMID: 33119297 - PMCID: PMC7662912 - DOI: 10.1021/jacs.0c07922
Chin LK*, Son T*, Hong JS, Liu AQ, Skog J, Castro CM, Weissleder R, Lee H*, Im H*
Plasmonic Sensors for Extracellular Vesicle Analysis: From Scientific Development to Translational Research.
ACS Nano. 2020;14(11):14528-14548 - PMID: 33119256 - PMCID: PMC8423498 - DOI: 10.1021/acsnano.0c07581
Poller WC, Nahrendorf M, Swirski FK
Hematopoiesis and Cardiovascular Disease.
Circ Res. 2020;126(8):1061-1085 - PMID: 32271679 - PMCID: PMC7153537 - DOI: 10.1161/CIRCRESAHA.120.315895
Schloss MJ, Swirski FK, Nahrendorf M
Modifiable Cardiovascular Risk, Hematopoiesis, and Innate Immunity.
Circ Res. 2020;126(9):1242-1259 - PMID: 32324501 - PMCID: PMC7185037 - DOI: 10.1161/CIRCRESAHA.120.315936
Li R, Ng TSC, Garlin MA, Weissleder R*, Miller MA*
Understanding the In Vivo Fate of Advanced Materials by Imaging
Adv Funct Mater. 2020;30(37):ePub - PMID: 38545084 - PMCID: PMC10972611 - DOI: 10.1002/adfm.201910369
Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK
Liver X receptors are required for thymic resilience and T cell output.
J Exp Med. 2020;217(10):ePub - PMID: 32716519 - PMCID: PMC7537384 - DOI: 10.1084/jem.20200318
Wang SJ, Li R, Ng TSC, Luthria G, Oudin MJ, Prytyskach M, Kohler RH, Weissleder R, Lauffenburger DA, Miller MA
Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy.
Sci Adv. 2020;6(21):ePub - PMID: 32937338 - PMCID: PMC7244320 - DOI: 10.1126/sciadv.aaz8521
Liebel M, Ortega Arroyo J, Beltrán VS, Osmond J, Jo A, Lee H, Quidant R, van Hulst NF
3D tracking of extracellular vesicles by holographic fluorescence imaging.
Sci Adv. 2020;6(45):ePub - PMID: 33148645 - PMCID: PMC7673696 - DOI: 10.1126/sciadv.abc2508
Foy BH, Gonçalves BP, Higgins JM
Unraveling Disease Pathophysiology with Mathematical Modeling.
Annu Rev Pathol. 2020;15:371-394 - PMID: 31977295 - DOI: 10.1146/annurev-pathmechdis-012419-032557
Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R
Ultra-fast cycling for multiplexed cellular fluorescence imaging.
Angew Chem Weinheim Bergstr Ger. 2020;132(17):6906-6913 - PMID: 34366494 - PMCID: PMC8340598 - DOI: 10.1002/ange.201915153
Kim Y, Sundrud MS, Zhou C, Edenius M, Zocco D, Powers K, Zhang M, Mazitschek R, Rao A, Yeo CY, Noss EH, Brenner MB, Whitman M, Keller TL
Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
Proc Natl Acad Sci U S A. 2020;117(16):8900-8911 - PMID: 32253314 - PMCID: PMC7183223 - DOI: 10.1073/pnas.1913788117
Chen IX, Newcomer K, Pauken KE, Juneja VR, Naxerova K, Wu MW, Pinter M, Sen DR, Singer M, Sharpe AH, Jain RK
A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade.
Proc Natl Acad Sci U S A. 2020;117(38):23684-23694 - PMID: 32907939 - PMCID: PMC7519254 - DOI: 10.1073/pnas.2002806117
Zaidman NA, Tomilin VN, Hassanzadeh Khayyat N, Damarla M, Tidmore J, Capen DE, Brown D, Pochynyuk OM, Pluznick JL
Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion.
Proc Natl Acad Sci U S A. 2020;117(42):26470-26481 - PMID: 33004624 - PMCID: PMC7584995 - DOI: 10.1073/pnas.2007620117
Algazi AP, Twitty CG, Tsai KK, Le M, Pierce R, Browning E, Hermiz R, Canton DA, Bannavong D, Oglesby A, Francisco M, Fong L, Pittet MJ, Arlauckas SP, Garris C, Levine LP, Bifulco C, Ballesteros-Merino C, Bhatia S, Gargosky S, Andtbacka RHI, Fox BA, Rosenblum MD, Daud AI
Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma.
Clin Cancer Res. 2020;26(12):2827-2837 - PMID: 32376655 - PMCID: PMC9354653 - DOI: 10.1158/1078-0432.CCR-19-2217
Muralidharan K, Yekula A, Small JL, Rosh ZS, Kang KM, Wang L, Lau S, Zheng H, Lee H, Bettegowda C, Chicoine MR, Kalkanis S, Shankar GM, Nahed BV, Curry WT, Jones PS, Cahill DP, Balaj L, Carter BS
TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas.
Clin Cancer Res. 2020;27(1):169-178 - PMID: 33051308 - PMCID: PMC7785705 - DOI: 10.1158/1078-0432.CCR-20-3083
Garris CS, Luke JJ
Dendritic Cells, the T-cell-inflamed Tumor Microenvironment, and Immunotherapy Treatment Response.
Clin Cancer Res. 2020;26(15):3901-3907 - PMID: 32332013 - PMCID: PMC7607412 - DOI: 10.1158/1078-0432.CCR-19-1321
Gastman B, Agarwal PK, Berger A, Boland G, Broderick S, Butterfield LH, Byrd D, Fecci PE, Ferris RL, Fong Y, Goff SL, Grabowski MM, Ito F, Lim M, Lotze MT, Mahdi H, Malafa M, Morris CD, Murthy P, Neves RI, Odunsi A, Pai SI, Prabhakaran S, Rosenberg SA, Saoud R, Sethuraman J, Skitzki J, Slingluff CL, Sondak VK, Sunwoo JB, Turcotte S, Yeung CC, Kaufman HL
Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee.
J Immunother Cancer. 2020;8(2):ePub - PMID: 33199512 - PMCID: PMC7670953 - DOI: 10.1136/jitc-2020-001583
Hulsmans M, Nahrendorf M
Proliferative, degradative smooth muscle cells promote aortic disease.
J Clin Invest. 2020;130(3):1096-1098 - PMID: 32039919 - PMCID: PMC7269557 - DOI: 10.1172/JCI134019
Battistone MA, Mendelsohn AC, Spallanzani RG, Allegretti AS, Liberman RN, Sesma J, Kalim S, Wall SM, Bonventre JV, Lazarowski ER, Brown D, Breton S
Pro-inflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice.
J Clin Invest. 2020;130(7):3734-3749 - PMID: 32287042 - PMCID: PMC7324186 - DOI: 10.1172/JCI134791
Ortiz-Orruño U, Jo A, Lee H, van Hulst NF, Liebel M
Precise Nanosizing with High Dynamic Range Holography.
Nano Lett. 2020;21(1):317-322 - PMID: 33346670 - PMCID: PMC8326875 - DOI: 10.1021/acs.nanolett.0c03699
Xiao X, Dev S, Canali S, Bayer A, Xu Y, Agarwal A, Wang CY, Babitt JL
Endothelial Bmp2 knockout exacerbates hemochromatosis in Hfe knockout mice but not Bmp6 knockout mice.
Hepatology. 2020;72(2):642-655 - PMID: 31778583 - PMCID: PMC7253321 - DOI: 10.1002/hep.31048
Hadjikhani N, Albrecht DS, Mainero C, Ichijo E, Ward N, Granziera C, Zürcher NR, Akeju O, Bonnier G, Price J, Hooker JM, Napadow V, Nahrendorf M, Loggia ML, Moskowitz MA
Extra-axial inflammatory signal in parameninges in migraine with visual aura.
Ann Neurol. 2020;87(6):939-949 - PMID: 32239542 - PMCID: PMC7313427 - DOI: 10.1002/ana.25731
Kim J, Jang HJ, Schellingerhout D, Lee SK, Kim H, Kim YD, Lee KY, Choi HY, Cho HJ, Jang SS, Jeon S, Kwon IC, Kim K, Ryu WS, Nahrendorf M, Choi S, Kim DE
Short-Term Cessation of Dabigatran Causes a Paradoxical Prothrombotic State.
Ann Neurol. 2020;89(3):444-458 - PMID: 33219556 - DOI: 10.1002/ana.25964
Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance.
Genome Biol. 2020;21(1):174 - PMID: 32669109 - PMCID: PMC7364565 - DOI: 10.1186/s13059-020-02085-1
Chand S, Jo A, Vellichirammal NN, Gowen A, Guda C, Schaal V, Odegaard K, Lee H, Pendyala G, Yelamanchili AV
Comprehensive Characterization of Nanosized Extracellular Vesicles from Central and Peripheral Organs: Implications for Preclinical and Clinical Applications
ACS Appl Mater Interfaces. 2020;9:8906–8919 - DOI: 10.1021/acsanm.0c01654
Koch PD, Rodell CB, Kohler RH, Pittet MJ, Weissleder R
Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy.
Cell Chem Biol. 2020;27(1):94-104.e5 - PMID: 31902676 - PMCID: PMC7422681 - DOI: 10.1016/j.chembiol.2019.12.007
Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, Atanasova MI, Chylek LA, Shi T, Yi L, Nicora CD, Claas A, Ng TSC, Kohler RH, Lauffenburger DA, Weissleder R, Miller MA, Qian WJ, Wiley HS, Sorger PK
Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.
Cell Syst. 2020;11(5):478-494.e9 - PMID: 33113355 - PMCID: PMC8009031 - DOI: 10.1016/j.cels.2020.10.002
Brown CR, Gupta S, Qin J, Racie T, He G, Lentini S, Malone R, Yu M, Matsuda S, Shulga-Morskaya S, Nair AV, Theile CS, Schmidt K, Shahraz A, Goel V, Parmar RG, Zlatev I, Schlegel MK, Nair JK, Jayaraman M, Manoharan M, Brown D, Maier MA, Jadhav V
Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates.
Nucleic Acids Res. 2020;48(21):11827-11844 - PMID: 32808038 - PMCID: PMC7708070 - DOI: 10.1093/nar/gkaa670
Calcagno DM, Ng RP, Toomu A, Zhang C, Huang K, Aguirre AD, Weissleder R, Daniels LB, Fu Z, King KR
Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and depend on Tet2, Nrf2, and Irf3
Sci Immunol. 2020;5(51):ePub - PMID: 32978242 - PMCID: PMC7808338 - DOI: 10.1126/sciimmunol.aaz1974
Pfirschke C, Engblom C, Gungabeesoon J, Lin Y, Rickelt S, Zilionis R, Messemaker M, Siwicki M, Gerhard GM, Kohl A, Meylan E, Weissleder R, Klein AM, Pittet MJ
Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils.
Cell Rep. 2020;32(12):108164 - PMID: 32966785 - PMCID: PMC7508173 - DOI: 10.1016/j.celrep.2020.108164
Kim IS, Wu J, Rahme GJ, Battaglia S, Dixit A, Gaskell E, Chen H, Pinello L, Bernstein BE
Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies.
Cell Rep. 2020;33(1):108222 - PMID: 33027665 - PMCID: PMC7646252 - DOI: 10.1016/j.celrep.2020.108222
Malka R, Brugnara C, Cialic R, Higgins JM
Non-Parametric Combined Reference Regions and Prediction of Clinical Risk.
Clin Chem. 2020;66(2):363-372 - PMID: 32040586 - PMCID: PMC7055670 - DOI: 10.1093/clinchem/hvz020
Ng TSC, Gunda V, Li R, Prytyskach M, Iwamoto Y, Kohler RH, Parangi S, Weissleder R, Miller MA
Detecting Immune Response to Therapies Targeting PDL1 and BRAF by Using Ferumoxytol MRI and Macrin in Anaplastic Thyroid Cancer
Radiology. 2020;298(1):123-132 - PMID: 33107799 - PMCID: PMC7771993 - DOI: 10.1148/radiol.2020201791
Wright ME, Yu JK, Jain D, Maeda A, Yeh SA, DaCosta RS, Lin CP, Santerre JP
Engineering functional microvessels in synthetic polyurethane random-pore scaffolds by harnessing perfusion flow.
Biomaterials . 2020;256:120183 - PMID: 32622017 - DOI: 10.1016/j.biomaterials.2020.120183
Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R
Single Extracellular Vesicle Protein Analysis Using Immuno- Droplet Digital Polymerase Chain Reaction Amplification
Adv Biosyst. 2020;:ePub - DOI: 10.1002/adbi.201900307
Van Deun J, Jo A, Li H, Lin HY, Weissleder R, Im H, Lee H
Integrated Dual-Mode Chromatography to Enrich Extracellular Vesicles from Plasma.
Adv Biosyst. 2020;4(12):e1900310 - PMID: 32351054 - PMCID: PMC7606548 - DOI: 10.1002/adbi.201900310
Ferguson S, Weissleder R
Modeling EV Kinetics for Use in Early Cancer Detection
Adv Biosyst. 2020;4(12):e1900305 - PMID: 32394646 - PMCID: PMC7658022 - DOI: 10.1002/adbi.201900305
Min J, Son T, Hong JS, Cheah PS Wegemann A, Murlidharan K, Weissleder R, Lee H, Im H
Plasmon-Enhanced Biosensing for Multiplexed Profiling of Extracellular Vesicles
Adv Biosyst. 2020;2020:2000003 - PMID: 32815321 - PMCID: PMC7718316 - DOI: 10.1002/adbi.202000003 - Cover
Yang KS, Lin HY, Curley C, Welch MW, Wolpin BM, Lee H, Weissleder R, Im H*, Castro CM*
Bead-Based Extracellular Vesicle Analysis Using Flow Cytometry.
Adv Biosyst. 2020;4(12):e2000203 - PMID: 33103361 - PMCID: PMC7718389 - DOI: 10.1002/adbi.202000203
Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R
Single Extracellular Vesicle Protein Analysis Using Immuno-Droplet Digital Polymerase Chain Reaction Amplification.
Adv Biosyst. 2020;4(12):e1900307 - PMID: 33274611 - PMCID: PMC8491538 - DOI: 10.1002/adbi.201900307
Weissleder R
The Magical World of Circulating Vesicles.
Adv Biosyst. 2020;4(12):e2000475 - PMID: 33274610 - DOI: 10.1002/adbi.202000475
Liu CL, Liu X, Wang Y, Deng Z, Liu T, Sukhova GK, Wojtkiewicz GR, Tang R, Zhang JY, Achilefu S, Nahrendorf M, Libby P, Wang X, Shi GP
Reduced Nhe1 (Na+-H+ Exchanger-1) Function Protects ApoE-Deficient Mice From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms.
Hypertension. 2020;76(1):87-100 - PMID: 32475310 - PMCID: PMC7289683 - DOI: 10.1161/HYPERTENSIONAHA.119.14485
Mahmood U, Bang A, Chen YH, Mak RH, Lorch JH, Hanna GJ, Nishino M, Manuszak C, Thrash EM, Severgnini M, Sanborn M, Sridharan V, Margalit DN, Tishler RB, Busse PM, Willers H, Mamon HJ, Yoo HJ, Pai SI, Wirth LJ, Haddad RI, Chau NG, Schoenfeld JD
A Randomized Phase 2 Study of Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma.
Int J Radiat Oncol Biol Phys. 2020;109(1):134-144 - PMID: 32781104 - PMCID: PMC9361179 - DOI: 10.1016/j.ijrobp.2020.08.018
Naxerova K
Defining the role of lymph node metastasis in systemic breast cancer evolution.
EBioMedicine. 2020;57:102852 - PMID: 32574957 - PMCID: PMC7322247 - DOI: 10.1016/j.ebiom.2020.102852
Härdtner C, Kornemann J, Krebs K, Ehlert CA, Jander A, Zou J, Starz C, Rauterberg S, Sharipova D, Dufner B, Hoppe N, Dederichs TS, Willecke F, Stachon P, Heidt T, Wolf D, von Zur Mühlen C, Madl J, Kohl P, Kaeser R, Boettler T, Pieterman EJ, Princen HMG, Ho-Tin-Noé B, Swirski FK, Robbins CS, Bode C, Zirlik A, Hilgendorf I
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering.
Basic Res Cardiol. 2020;115(6):78 - PMID: 33296022 - PMCID: PMC7725697 - DOI: 10.1007/s00395-020-00838-4
Nahrendorf M, Hoyer FF, Meerwaldt AE, van Leent MMT, Senders ML, Calcagno C, Robson PM, Soultanidis G, Pérez-Medina C, Teunissen AJP, Toner YC, Ishikawa K, Fish K, Sakurai K, van Leeuwen EM, Klein ED, Sofias AM, Reiner T, Rohde D, Aguirre AD, Wojtkiewicz G, Schmidt S, Iwamoto Y, Izquierdo-Garcia D, Caravan P, Swirski FK, Weissleder R, Mulder WJM
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs.
Circ Cardiovasc Imaging. 2020;13(10):e010586 - PMID: 33076700 - PMCID: PMC7583675 - DOI: 10.1161/CIRCIMAGING.120.010586
Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK
Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.
FASEB J. 2020;34(10):13877-13884 - PMID: 32856766 - PMCID: PMC7461169 - DOI: 10.1096/fj.202001700RR
Bouley R, Yui N, Terlouw A, Cheung PW, Brown D
Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells.
Cells. 2020;9(4):ePub - PMID: 32340337 - PMCID: PMC7226349 - DOI: 10.3390/cells9041057
Castro MM, Kim B, Games PD, Hill E, Neves CA, Serrão JE, Breton S, Machado-Neves M
Distribution pattern of ZO-1 and claudins in the epididymis of vampire bats.
Tissue Barriers. 2020;8(3):1779526 - PMID: 32552339 - PMCID: PMC7549744 - DOI: 10.1080/21688370.2020.1779526
Edelson PK, James KE, Leong A, Arenas J, Cayford M, Callahan MJ, Bernstein SN, Tangren JS, Hivert MF, Higgins JM, Nathan DM, Powe CE
Longitudinal Changes in the Relationship Between Hemoglobin A1c and Glucose Tolerance Across Pregnancy and Postpartum.
J Clin Endocrinol Metab. 2020;105(5):e1999-2007 - PMID: 32010954 - PMCID: PMC7236626 - DOI: 10.1210/clinem/dgaa053
Pai SI, Faquin WC, Sadow PM, Pittet MJ, Weissleder R
New Technology on the Horizon: Fast Analytical Screening Technique FNA (FAST-FNA) Enables Rapid, Multiplex Biomarker Analysis in Head and Neck Cancers
Cancer Cytopathol. 2020;128(11):782-791 - PMID: 32841527 - PMCID: PMC8276888 - DOI: 10.1002/cncy.22305
Marquard AN, Carlson JCT, Weissleder R
Expanding the scope of antibody rebridging with new pyridazinedione-TCO constructs.
Bioconjug Chem. 2020;31(6):1616-1623 - PMID: 32286045 - PMCID: PMC7788567 - DOI: 10.1021/acs.bioconjchem.0c00155
O'Malley DM, Matulonis UA, Birrer MJ, Castro CM, Gilbert L, Vergote I, Martin LP, Mantia-Smaldone GM, Martin AG, Bratos R, Penson RT, Malek K, Moore KN
Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer.
Gynecol Oncol. 2020;157(2):379-385 - PMID: 32081463 - DOI: 10.1016/j.ygyno.2020.01.037
Liston SD, Whitesell L, McLellan CA, Mazitschek R, Petraitis V, Petraitiene R, Kavaliauskas P, Walsh TJ, Cowen LE
Antifungal activity of gepinacin-scaffold GPI anchor biosynthesis inhibitors with improved metabolic stability.
Antimicrob Agents Chemother. 2020;64(10):ePub - PMID: 32661007 - PMCID: PMC7508603 - DOI: 10.1128/AAC.00899-20
Kilic T, Weissleder R, Lee H
Molecular and immunological diagnostic tests of COVID-19 – current status and challenges
iScience. 2020;23(8):101406 - PMID: 32771976 - PMCID: PMC7381402 - DOI: 10.1016/j.isci.2020.101406
Badr CE, da Hora CC, Kirov AB, Tabet E, Amante R, Maksoud S, Nibbs AE, Fitzsimons E, Boukhali M, Chen JW, Chiu NHL, Nakano I, Haas W, Mazitschek R, Tannous BA
Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation.
ACS Chem Biol. 2020;15(6):1445-1454 - PMID: 32338864 - PMCID: PMC7995447 - DOI: 10.1021/acschembio.0c00104
Figueiredo JL, Santa-Cruz F, Lima-Filho JL, Hilgendorf I, Aikawa M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK, Robbins CS
A durable murine model of spleen transplantation with arterial and venous anastomoses.
Sci Rep. 2020;10(1):3979 - PMID: 32132617 - PMCID: PMC7055260 - DOI: 10.1038/s41598-020-60983-7
Vinegoni C, Fumene Feruglio P, Courties G, Schmidt S, Hulsmans M, Lee S, Wang R, Sosnovik D, Nahrendorf M, Weissleder R
Fluorescence microscopy tensor imaging representations for large-scale dataset analysis.
Sci Rep. 2020;10(1):5632 - PMID: 32221334 - PMCID: PMC7101442 - DOI: 10.1038/s41598-020-62233-2
Kim B, Breton S
Androgens are essential for epithelial cell recovery after efferent duct ligation in the initial segment of the mouse epididymis.
Biol Reprod. 2020;102(1):76-83 - PMID: 31403160 - PMCID: PMC7334622 - DOI: 10.1093/biolre/ioz152
Rodell CB, Baldwin P, Fernandez B, Weissleder R, Sridhar S, Dubach JM
Quantification of Cellular Drug Biodistribution Addresses Challenges in Evaluating in vitro and in vivo Encapsulated Drug Delivery.
Adv Ther (Weinh). 2020;4(3):ePub - PMID: 33997266 - PMCID: PMC8114878 - DOI: 10.1002/adtp.202000125
Qi Y, Reyes A, Johnstone SE, Aryee MJ, Bernstein BE, Zhang B
Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization.
Biophys J. 2020;119(9):1905-1916 - PMID: 33086041 - PMCID: PMC7677132 - DOI: 10.1016/j.bpj.2020.09.009
Lebow ES, Hwang WL, Zieminski S, Wang Y, Niemierko A, Mehan WA, Oh KS, Khandekar M, Willers H, Shih HA
Early experience with hippocampal avoidance whole brain radiation therapy and simultaneous integrated boost for brain metastases.
J Neurooncol. 2020;148(1):81-88 - PMID: 32307637 - DOI: 10.1007/s11060-020-03491-y
Kwon S, Kim S, Giovannucci EL, Hidalgo M, Markey MK, Bovik AC, Kwon MJ, Kim KJ, Im H, Park JY, Bang S, Park SW, Song SY, Chung MJ
Lewis Antigen Phenotype and Survival of Patients With Pancreatic Cancer.
Pancreas. 2020;49(10):1348-1354 - PMID: 33122524 - DOI: 10.1097/MPA.0000000000001687
Fumene Feruglio P, Vinegoni C, Weissleder R
Extended dynamic range imaging for noise mitigation in fluorescence anisotropy imaging.
J Biomed Opt. 2020;25(8):ePub - PMID: 32820624 - PMCID: PMC7439791 - DOI: 10.1117/1.JBO.25.8.086003
Nahrendorf M, Abbate A, Narula J
Deciphering post-infarct inflammation: Should it heal, would it hurt?
J Nucl Cardiol. 2020;27(6):2100-2102 - PMID: 32086743 - DOI: 10.1007/s12350-020-02053-z
Nahrendorf M, Abbate A, Narula J
Correction to: Deciphering post-infarct inflammation: Should it heal, would it hurt?
J Nucl Cardiol. 2020;27(4):1384 - PMID: 32140993 - DOI: 10.1007/s12350-020-02090-8
O'Shea A, Kilcoyne A, Hedgire SS, Harisinghani MG
Pelvic lymph nodes and pathways of disease spread in male pelvic malignancies.
Abdom Radiol (NY). 2020;45(7):2198-2212 - PMID: 31673716 - DOI: 10.1007/s00261-019-02285-9
Atre ID, Eurboonyanun K, O'Shea A, Lahoud RM, Shih A, Kalva S, Harisinghani MG, Hedgire S
Predictors of transmural intestinal necrosis in patients presenting with acute mesenteric ischemia on computed tomography.
Abdom Radiol (NY). 2020;47(5):1636-1643 - PMID: 32382818 - DOI: 10.1007/s00261-020-02558-8
Atre ID, Eurboonyanun K, Noda Y, Parakh A, O'Shea A, Lahoud RM, Sell NM, Kunitake H, Harisinghani MG
Utility of texture analysis on T2-weighted MR for differentiating tumor deposits from mesorectal nodes in rectal cancer patients, in a retrospective cohort.
Abdom Radiol (NY). 2020;46(2):459-468 - PMID: 32700214 - DOI: 10.1007/s00261-020-02653-w
Raisbeck JC, Allen M, Weissleder R, Im H, Lee H
Evolution Strategies Converges to Finite Differences
arXiv. 2020;:ePub
Foy BH, Carlson JCT, Reinertsen E, Padros Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM
Elevated RDW is Associated with Increased Mortality Risk in COVID-19
medRxiv. 2020;:ePub - DOI: 10.1101/2020.05.05.20091702
Baskaran JP, Weldy A, Guarin J, Munoz G, Shpilker PH, Kotlik M, Subbiah N, Wishart A, Peng Y, Miller MA, Cowen L, Oudin MJ
Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer.
APL Bioeng. 2020;4(2):026105 - PMID: 32455252 - PMCID: PMC7202897 - DOI: 10.1063/1.5143779
Liu Z, Ahn MH, Kurokawa T, Ly A, Zhang G, Wang F, Yamada T, Sadagopan A, Cheng J, Ferrone CR, Liss AS, Honselmann KC, Wojtkiewicz GR, Ferrone S, Wang X
A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma.
J Transl Med. 2020;18(1):255 - PMID: 32580742 - PMCID: PMC7315507 - DOI: 10.1186/s12967-020-02414-9
Moradi Tuchayi S, Tam J, Wojtkiewicz GR, Kawa NI, Javorsky E, Anderson RR, Garibyan L
Injectable slurry for selective destruction of neck adipose tissue in New Zealand obese mouse model.
Sleep Breath. 2020;24(4):1715-1718 - PMID: 32474829 - DOI: 10.1007/s11325-020-02111-3
Koch PD, Pittet MJ, Weissleder R
The chemical biology of IL-12 production via the non-canonical NFkB pathway
RSC Chemical Biology. 2020;1:166-176 - PMID: 34458756 - PMCID: PMC8341911 - DOI: 10.1039/d0cb00022a
Bachar Issa TH, Vinegoni C, Shaw A, Fumene Feruglio P, Weissleder R, Uminsky D
Video-Rate Acquisition Fluorescence Microscopy via Generative Adversarial Networks
EasyChair. 2020;:ePub
Naranbhai V, Chang CC, Beltran WFG, Miller TE, Astudillo MG, Villalba JA, Yang D, Gelfand J, Bernstein BE, Feldman J, Hauser BM, Caradonna TM, Alter G, Murali MR, Jasrasaria R, Quinlan J, Xerras DC, Betancourt JR, Louis DN, Schmidt AG, Lennerz J, Poznansky MC, Iafrate AJ
High seroprevalence of anti-SARS-CoV-2 antibodies in Chelsea, Massachusetts.
J Infect Dis. 2020;222(12):1955-1959 - PMID: 32906151 - PMCID: PMC7499676 - DOI: 10.1093/infdis/jiaa579
Yue H, Nowak RP, Overwijn D, Payne NC, Fischinger S, Atyeo C, Baden LR, Nilles EJ, Karlson EW, Yu XG, Li JZ, Alter G, Mazitschek R, Fischer ES
Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma.
medRxiv. 2020;:ePub - PMID: 32909004 - PMCID: PMC7480056 - DOI: 10.1101/2020.09.01.20184101
Foy BH, Carlson JCT, Reinertsen E, Padros I Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM
Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection.
JAMA Netw Open. 2020;3(9):e2022058 - PMID: 32965501 - PMCID: PMC7512057 - DOI: 10.1001/jamanetworkopen.2020.22058
Snyder PJ, Alber J, Alt C, Bain LJ, Bouma BE, Bouwman FH, DeBuc DC, Campbell MCW, Carrillo MC, Chew EY, Cordeiro MF, Dueñas MR, Fernández BM, Koronyo-Hamaoui M, La Morgia C, Carare RO, Sadda SR, van Wijngaarden P, Snyder HM
Retinal imaging in Alzheimer's and neurodegenerative diseases.
Alzheimers Dement. 2020;17(1):103-111 - PMID: 33090722 - PMCID: PMC8062064 - DOI: 10.1002/alz.12179
Goulet DR, Foster JP, Zawistowski JS, Bevill SM, Noël MP, Olivares-Quintero JF, Sciaky N, Singh D, Santos C, Pattenden SG, Davis IJ, Johnson GL
Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer.
Mol Cancer Res. 2020;18(11):1685-1698 - PMID: 32753473 - PMCID: PMC7642176 - DOI: 10.1158/1541-7786.MCR-19-1011
Yao Q, Epstein CB, Banskota S, Issner R, Kim Y, Bernstein BE, Pinello L, Asgari MM
Epigenetic alterations in keratinocyte carcinoma.
J Invest Dermatol. 2020;141(5):1207-1218 - PMID: 33212152 - PMCID: PMC8068579 - DOI: 10.1016/j.jid.2020.10.018
Kim H, Choia SK, Ahn J, Yu H, Kyoungha Min K, Hong C, Shin IS, Lee S, Lee H, Im H, Ko JG, Kim E
Kaleidoscopic fluorescent arrays for machine-learning-based point-of-care chemical sensing
Sensors and Actuators B: Chemical. 2020;329:129248 - DOI: 10.1016/j.snb.2020.129248
Pai SI, Cesano A, Marincola FM
The Paradox of Cancer Immune Exclusion: Immune Oncology Next Frontier.
Cancer Treat Res. 2020;180:173-195 - PMID: 32215870 - PMCID: PMC7423459 - DOI: 10.1007/978-3-030-38862-1_6
Wolkow N, Jakobiec FA, Afrogheh AH, Kidd M, Eagle RC, Pai SI, Faquin WC
PD-L1 and PD-L2 Expression Levels Are Low in Primary and Secondary Adenoid Cystic Carcinomas of the Orbit: Therapeutic Implications.
Ophthalmic Plast Reconstr Surg. 2020;36(5):444-450 - PMID: 31990894 - PMCID: PMC7423458 - DOI: 10.1097/IOP.0000000000001585
Wolkow N, Jakobiec FA, Afrogheh AH, Pai SI, Faquin WC
High Expression of Programmed Death Ligand 1 and Programmed Death Ligand 2 in Ophthalmic Sebaceous Carcinoma: The Case for a Clinical Trial of Checkpoint Inhibitors.
Am J Ophthalmol. 2020;220:128-139 - PMID: 32730911 - PMCID: PMC9361189 - DOI: 10.1016/j.ajo.2020.07.031
Mehta A, Hwang WL, Weekes C
The present and future of systemic and microenvironment-targeted therapy for pancreatic adenocarcinoma.
Ann Pancreat Cancer. 2020;3:ePub - PMID: 33294843 - PMCID: PMC7720884 - DOI: 10.21037/apc-2020-pda-05
Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma.
CA Cancer J Clin. 2020;70(5):375-403 - PMID: 32683683 - PMCID: PMC7722002 - DOI: 10.3322/caac.21626
Hoffman HI, Guo JA, Hawkins MA, Bridgewater JA, Wo JY, Hong TS, Hwang WL
Silver Linings: An Opportunity to Improve Clinical Paradigms After the COVID-19 Pandemic.
JCO Oncol Pract. 2020;16(9):532-534 - PMID: 32469687 - DOI: 10.1200/OP.20.00335
Kim DW, Buzurovic IM, Mahal BV, Hwang W, Oladeru OT, O'Farrell DA, Harris TC, Margalit DN, Lam M, Devlin PM
Combined interstitial and surface high-dose-rate brachytherapy treatment of squamous cell carcinoma of the hand.
J Contemp Brachytherapy. 2020;12(1):48-52 - PMID: 32190070 - PMCID: PMC7073341 - DOI: 10.5114/jcb.2020.92408
Pike LRG, Royce TJ, Mahal AR, Kim DW, Hwang WL, Mahal BA, Sanford NN
Outcomes of HPV-Associated Squamous Cell Carcinoma of the Head and Neck: Impact of Race and Socioeconomic Status.
J Natl Compr Canc Netw. 2020;18(2):177-184 - PMID: 32023531 - PMCID: PMC7384230 - DOI: 10.6004/jnccn.2019.7356
Hwang WL, Jagadeesh KA, Guo JA, Hoffman HI, Yadollahpour P, Mohan R, Drokhlyansky E, Van Wittenberghe N, Ashenberg O, Farhi S, Schapiro D, Reeves J, Zollinger DR, Eng G, Schenkel JM, Freed-Pastor WA, Rodrigues C, Gould J, Lambden C, Porter C, Tsankov A, Dionne D, Abbondanza D, Waldman J, Cuoco M, Nguyen L, Delorey T, Phillips D, Ciprani D, Kern M, Mehta A, Fuhrman K, Fropf R, Beechem J, Loeffler JS, Ryan DP, Weekes CD, Ting DT, Ferrone CR, Wo JY, Hong TS, Aguirre AJ, Rozenblatt-Rosen O, Mino-Kenudson M, Fernandez-del Castillo C, Liss AS, Jacks TE, Regev A
Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment
bioRxiv. 2020;:ePub - DOI: 10.1101/2020.08.25.267336
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