Chemical phylogenetics of histone deacetylases.
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase
Light-controlled modulation of gene expression by chemical optoepigenetic probes.
Quantitating drug-target engagement in single cells in vitro and in vivo.
SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing.
Dev Cell. 2013;26(6):565-577 - PMID: 24091011 - DOI: 10.1016/j.devcel.2013.08.016
Imaging inflammation of the pancreatic islets in type 1 diabetes.
Proc Natl Acad Sci U S A. 2004;101(34):12634-9 - PMID: 15304647 - PMCID: PMC515109 - DOI: 10.1073/pnas.0404307101
Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate.
Proc Natl Acad Sci U S A. 2004;101(33):12294-9 - PMID: 15304657 - PMCID: PMC514472 - DOI: 10.1073/pnas.0401137101
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-{beta} signals in vivo
Proc Natl Acad Sci U S A. 2005;102(2):419-24 - PMID: 15623559 - PMCID: PMC544311 - DOI: 10.1073/pnas.0408197102
Use of gene expression profiling to direct in vivo molecular imaging of lung cancer
Proc Natl Acad Sci U S A. 2005;102(40):14404-14409 - PMID: 16183744 - PMCID: PMC1242291 - DOI: 10.1073/pnas.0503920102
Volumetric tomography of fluorescent proteins through small animals in vivo
Proc Natl Acad Sci U S A. 2005;102:18252-18257 - PMID: 16344470 - PMCID: PMC1317905 - DOI: 10.1073/pnas.0504628102
Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678 - DOI: 10.1073/pnas.0601273103
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease.
Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459 - DOI: 10.1073/pnas.0604260103
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940 - DOI: 10.1073/pnas.0605496103
The B1-subunit of the H(+) ATPase is required for maximal urinary acidification.
Proc Natl Acad Sci U S A. 2005;102(38):13616-21 - PMID: 16174750 - PMCID: PMC1224669 - DOI: 10.1073/pnas.0506769102
In vivo imaging of T cell delivery to tumors after adoptive transfer therapy
Proc Natl Acad Sci U S A. 2007;104:12457-12461 - PMID: 17640914 - PMCID: PMC1941490 - DOI: 10.1073/pnas.0704460104
Mast cells are an essential hematopoietic component for polyp development.
Proc Natl Acad Sci U S A. 2007;104:19977-82 - PMID: 18077429 - PMCID: PMC2148408 - DOI: 10.1073/pnas.0704620104
Perturbational profiling of nanomaterial biologic activity.
Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702 - DOI: 10.1073/pnas.0802878105
From oligonucleotide shapes to genomic SELEX: novel biological regulatory loops.
Proc Natl Acad Sci U S A. 1997;94:59-64 - PMID: 8990161 - PMCID: PMC19236 - DOI: 10.1073/pnas.94.1.59
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.
Proc Natl Acad Sci U S A. 2008;105(28):9751-6 - PMID: 18607002 - PMCID: PMC2474517 - DOI: 10.1073/pnas.0710413105
Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments.
Proc Natl Acad Sci U S A. 1997;94(5):1692-7 - PMID: 9050840 - PMCID: PMC19978 - DOI: 10.1073/pnas.94.5.1692
Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase
Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593 - DOI: 10.1073/pnas.0803945105
Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo.
Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726 - DOI: 10.1073/pnas.0804798105
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.
Proc Natl Acad Sci U S A. 2008;105(43):16525-30 - PMID: 18946036 - PMCID: PMC2571912 - DOI: 10.1073/pnas.0808750105
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene function in gliomagenesis
Proc Natl Acad Sci U S A. 0;:ePub
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331 - DOI: 10.1073/pnas.0813314106
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy.
Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771 - DOI: 10.1073/pnas.0806647106
Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283 - DOI: 10.1073/pnas.0810338106
Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin.
Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071 - DOI: 10.1073/pnas.0811750106
Rapid detection and profiling of cancer cells in fine-needle aspirates.
Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371 - DOI: 10.1073/pnas.0902365106
Identification of genes conferring resistance to 5-fluorouracil.
Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317 - DOI: 10.1073/pnas.0901451106
Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.
Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449 - DOI: 10.1073/pnas.0902408106
Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.
Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102
Sickle cell vasoocclusion and rescue in a microfluidic device.
Proc Natl Acad Sci U S A. 2007;104(51):20496-500 - PMID: 18077341 - PMCID: PMC2154459 - DOI: 10.1073/pnas.0707122105
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Proc Natl Acad Sci U S A. 2010;107(4):1565-70 - PMID: 20080688 - PMCID: PMC2824379 - DOI: 10.1073/pnas.0908682107
Regenerative Medicine Special Feature: Engineered vascularized bone grafts.
Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421 - DOI: 10.1073/pnas.0905445107
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease.
Proc Natl Acad Sci U S A. 2010;107(11):5124-9 - PMID: 20194748 - PMCID: PMC2841922 - DOI: 10.1073/pnas.0911929107
Hybrid PET-optical imaging using targeted probes
Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879 - DOI: 10.1073/pnas.0915163107
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease.
Proc Natl Acad Sci U S A. 2010;107(28):12617-22 - PMID: 20616024 - PMCID: PMC2906581 - DOI: 10.1073/pnas.1006774107
Physiological and pathological population dynamics of circulating human red blood cells.
Proc Natl Acad Sci U S A. 2010;107(47):20587-92 - PMID: 21059904 - PMCID: PMC2996693 - DOI: 10.1073/pnas.1012747107
Deletion of hensin/DMBT1 blocks conversion of {beta}- to {alpha}-intercalated cells and induces distal renal tubular acidosis.
Proc Natl Acad Sci U S A. 2010;107(50):21872-7 - PMID: 21098262 - PMCID: PMC3003085 - DOI: 10.1073/pnas.1010364107
Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes.
Proc Natl Acad Sci U S A. 2010;108(2):492-7 - PMID: 21183721 - PMCID: PMC3021060 - DOI: 10.1073/pnas.1016789108
Measuring single-cell density.
Proc Natl Acad Sci U S A. 2011;108(27):10992-10996 - PMID: 21690360 - PMCID: PMC3131325 - DOI: 10.1073/pnas.1104651108
Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells.
Proc Natl Acad Sci U S A. 2011;108(36):14908-13 - PMID: 21737748 - PMCID: PMC3169118 - DOI: 10.1073/pnas.1109023108
Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth.
Proc Natl Acad Sci U S A. 2011;108(36):14902-7 - PMID: 21746931 - PMCID: PMC3169132 - DOI: 10.1073/pnas.1108892108
Accurate measurement of pancreatic islet {beta}-cell mass using a second-generation fluorescent exendin-4 analog.
Proc Natl Acad Sci U S A. 2011;108(31):12815-20 - PMID: 21768367 - PMCID: PMC3150928 - DOI: 10.1073/pnas.1109859108
Origins of tumor-associated macrophages and neutrophils.
Proc Natl Acad Sci U S A. 2012;109(7):2491-6 - PMID: 22308361 - PMCID: PMC3289379 - DOI: 10.1073/pnas.1113744109
Reactive polymer enables efficient in vivo bioorthogonal chemistry.
Proc Natl Acad Sci U S A. 2012;109(13):4762-7 - PMID: 22411831 - PMCID: PMC3324005 - DOI: 10.1073/pnas.1113466109
Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.
Proc Natl Acad Sci U S A. 2012;109(27):E1868-77 - PMID: 22699504 - PMCID: PMC3390871 - DOI: 10.1073/pnas.1116889109
Implantable microenvironments to attract hematopoietic stem/cancer cells.
Proc Natl Acad Sci U S A. 2012;109(48):19638-43 - PMID: 23150542 - PMCID: PMC3511730 - DOI: 10.1073/pnas.1208384109
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
Proc Natl Acad Sci U S A. 2012;109(52):21444-9 - PMID: 23236189 - PMCID: PMC3535589 - DOI: 10.1073/pnas.1217972110