Weissleder R, Lee H

Automated molecular-image cytometry and analysis in modern oncology
Nature Review Materials. 2020;:ePub - DOI: 10.1038/s41578-020-0180-6

Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
Cell. 2015;160(6):1246-60 - PMID: 25748654 - PMCID: PMC4380877 - DOI: 10.1016/j.cell.2015.02.038

Song J, Cho MH, Cho H, Song Y, Lee SW, Nam HC, Yoon TH, Shin JC, Hong JS, Kim Y, Ekanayake E, Jeon J, You DG, Im SG, Choi GS, Park JS, Carter BC, Balaj L, Seo AN, Miller MA, Park SY, Kang T, Castro CM, Lee H

Amplifying mutational profiling of extracellular vesicle mRNA with SCOPE.
Nat Biotechnol. 2024;43(9):1485-1495 - PMID: 39375445 - DOI: 10.1038/s41587-024-02426-6

Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H*

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947 - DOI: 10.1038/nbt.2886

Shao H, Im H, Castro CM, Breakefield X, Weissleder R, Lee H

New Technologies for Analysis of Extracellular Vesicles.
Chem Rev. 2018;118(4):1917-1950 - PMID: 29384376 - PMCID: PMC6029891 - DOI: 10.1021/acs.chemrev.7b00534

Lee H, Shin TH, Cheon J, Weissleder R

Recent Developments in Magnetic Diagnostic Systems
Chem Rev. 2015;115(19):10690-724 - PMID: 26258867 - PMCID: PMC5791529 - DOI: 10.1021/cr500698d

Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB*

Single-cell magnetic imaging using a quantum diamond microscope.
Nat Methods. 2015;12(8):736-738 - PMID: 26098019 - PMCID: PMC4521973 - DOI: 10.1038/nmeth.3449

Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA

Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.
Cancer Discov. 2016;6(4):382-99 - PMID: 26984351 - PMCID: PMC5087317 - DOI: 10.1158/2159-8290.CD-15-0933

Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R

Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection
Nat Nanotechnol. 2010;5(9):660-5 - PMID: 20676091 - PMCID: PMC2934903 - DOI: 10.1038/nnano.2010.148

Chung HJ, Castro CM, Im H, Lee H*, Weissleder R*

A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria
Nat Nanotechnol. 2013;8(5):369-75 - PMID: 23644570 - PMCID: PMC3711657 - DOI: 10.1038/nnano.2013.70

Park J, Park JS, Huang CH, Jo A, Cook K, Wang R, Lin HY, Van Deun J, Li H, Min J, Wang L, Yoon G, Carter BS, Balaj L, Choi GS, Castro CM, Weissleder R, Lee H

An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma
Nat Biomed Eng. 2021;5(7):678-689 - PMID: 34183802 - PMCID: PMC8437135 - DOI: 10.1038/s41551-021-00752-7

Cheong J, Yu H, Lee CY, Lee JU, Choi HJ, Lee JH, Lee H, Cheon J

Fast detection of SARS-CoV-2 RNA via the integration of plasmonic thermocycling and fluorescence detection in a portable device.
Nat Biomed Eng. 2020;4(12):1159-1167 - PMID: 33273713 - PMCID: PMC8202505 - DOI: 10.1038/s41551-020-00654-0

Lee H, Castro CM

Thermophoretically enriched detection.
Nat Biomed Eng. 2019;3(3):163-164 - PMID: 30948812 - DOI: 10.1038/s41551-019-0364-9

Im H, Pathania D, McFarland PJ, Sohani AR, Degani I, Allen M, Coble M, Kilcoyne A, Hong S, Rohrer L, Abramson JS, Dryden-Peterson S, Fexon L, Pivovarov M, Chabner B, Lee H, Castro CM, Weissleder R

Design and clinical validation of a point-of-care device for the diagnosis of lymphoma via contrast- enhanced microholography and machine learning
Nat Biomed Eng. 2018;2(9):666-674 - PMID: 30555750 - PMCID: PMC6291220 - DOI: 10.1038/s41551-018-0265-3

Lee H, Sun E, Ham D, Weissleder R

Chip-NMR biosensor for detection and molecular analysis of cells.
Nature Med. 2008;14(8):869-74 - PMID: 18607350 - PMCID: PMC2729055 - DOI: 10.1038/nm.1711

Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R*, Lee H*

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
Nature Med. 2012;18(12):1835-1840 - PMID: 23142818 - PMCID: PMC3518564 - DOI: 10.1038/nm.2994

Kilic T, Gessner I, Cho Y, Jeong N, Quintana J, Weissleder R, Lee H

Zwitterionic polymer electroplating facilitates the preparation of electrode surface for biosensing.
Adv Mater. 2021;34(8):e2107892 - PMID: 34890082 - PMCID: PMC8881349 - DOI: 10.1002/adma.202107892

Liong M, Shao H, Haun JB, Lee H, Weissleder R

Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications.
Adv Mater. 2010;22(45):5168-72 - PMID: 20859943 - PMCID: PMC2993874 - DOI: 10.1002/adma.201002219

Liong M, Tassa C, Shaw SY, Lee H, Weissleder R

Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization.
Adv Mater. 2011;23(36):H254-7 - PMID: 21780311 - PMCID: PMC3584698 - DOI: 10.1002/adma.201101401

Yoon TJ*, Lee H*, Shao H, Hilderbrand SA, Weissleder R

Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles.
Adv Mater. 2011;23(41):4793-7 - PMID: 21953810 - PMCID: PMC3224986 - DOI: 10.1002/adma.201102948

Hong S, Pirovich D, Kilcoyne A, Huang CH, Lee H, Weissleder R

Supramolecular Metallo-Bioadhesive for Minimally Invasive Use
Adv Mater. 2016;28(39):8675-8680 - PMID: 27515068 - PMCID: PMC5144581 - DOI: 10.1002/adma.201602606

Cheon J, Qin J, Lee LP, Lee H

Advances in Biosensor Technologies for Infection Diagnostics.
Acc Chem Res. 2022;55(2):121-122 - PMID: 35038867 - DOI: 10.1021/acs.accounts.1c00647

Lee CY, Degani I, Cheong J, Weissleder R, Lee JH, Cheon J, Lee H

Development of Integrated Systems for On-Site Infection Detection.
Acc Chem Res. 2021;54(21):3991-4000 - PMID: 34677927 - PMCID: PMC9099220 - DOI: 10.1021/acs.accounts.1c00498

Barth I, Lee H

Nanophotonic sensing and label-free imaging of extracellular vesicles.
Light Sci Appl. 2025;14(1):177 - PMID: 40295495 - PMCID: PMC12037801 - DOI: 10.1038/s41377-025-01866-2

Barth I, Lee H

Phase-driven progress in nanophotonic biosensing.
Light Sci Appl. 2024;13(1):76 - PMID: 38494520 - PMCID: PMC10944832 - DOI: 10.1038/s41377-024-01415-3

Chapman S, Dobrovolskaia M, Farahani K, Goodwin A, Joshi A, Lee H, Meade T, Pomper M, Ptak K, Rao J, Singh R, Sridhar S, Stern S, Wang A, Weaver JB, Woloschak G, Yang L

Nanoparticles for cancer imaging: The good, the bad, and the promise.
Nano Today. 2013;8(5):454-460 - PMID: 25419228 - PMCID: PMC4240321 - DOI: 10.1016/j.nantod.2013.06.001

Yu H, Lee H, Cheong J, Woo SW, Oh J, Oh HK, Lee JH, Zheng H, Castro CM, Yoo YE, Kim MG, Cheon J, Weissleder R, Lee H

A rapid assay provides on-site quantification of tetrahydrocannabinol in oral fluid
Sci Transl Med. 2021;13(616):eabe2352 - PMID: 34669441 - PMCID: PMC9126021 - DOI: 10.1126/scitranslmed.abe2352 - Cover

Min J*, Chin LK*, Oh J, Landeros C, Vinegoni C, Lee J, Lee SJ, Park JY, Liu AQ, Castro CM, Lee H, Im H, Weissleder R

CytoPAN—Portable cellular analyses for rapid point-of-care cancer diagnosis
Sci Transl Med. 2020;12:eaaz9746 - PMID: 32759277 - PMCID: PMC8217912 - DOI: 10.1126/scitranslmed.aaz9746

Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R.

Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples
Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - DOI: 10.1126/scitranslmed.3002048

Weissleder R, Lee H, Ko J, Pittet MJ

COVID-19 diagnostics in context
Sci Transl Med. 2020;12(546):eabc1931 - PMID: 32493791 - DOI: 10.1126/scitranslmed.abc1931

Issadore D, Chung J*, Shao H*, Liong M, Ghazani AA, Castro CM, Weissleder R*, Lee H*

Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector
Sci Transl Med. 2012;4 (141):141ra92 - PMID: 22764208 - PMCID: PMC3603277 - DOI: 10.1126/scitranslmed.3003747

Yang KS*, Im H*, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R

Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy
Sci Transl Med. 2017;9(391):eaal3226 - PMID: 28539469 - PMCID: PMC5846089 - DOI: 10.1126/scitranslmed.aal3226

Lee H*, Yoon TJ*, Weissleder R

Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System.
Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069 - DOI: 10.1002/anie.200901791

Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R

Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers.
Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171 - DOI: 10.1002/anie.201105670

Yoon TJ*, Lee H*, Shao H, Weissleder R

Highly magnetic core-shell nanoparticles with a unique magnetization mechanism.
Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859 - DOI: 10.1002/anie.201100101

Budin G*, Chung HJ*, Lee H, Weissleder R

A Magnetic Gram Stain for Bacterial Detection.
Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380 - DOI: 10.1002/anie.201202982

Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG

Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres.
ACS Nano. 2008;2(2):197-202 - PMID: 19206619 - DOI: 10.1021/nn700344x

Chin LK*, Son T*, Hong JS, Liu AQ, Skog J, Castro CM, Weissleder R, Lee H*, Im H*

Plasmonic Sensors for Extracellular Vesicle Analysis: From Scientific Development to Translational Research.
ACS Nano. 2020;14(11):14528-14548 - PMID: 33119256 - PMCID: PMC8423498 - DOI: 10.1021/acsnano.0c07581

Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca A, Breakefield XO, Lee H, Weissleder R

Multiplexed Profiling of Single Extracellular Vesicles.
ACS Nano. 2018;12(1):494-503 - PMID: 29286635 - PMCID: PMC5898240 - DOI: 10.1021/acsnano.7b07060

Huang CH, Park YI, Lin HY, Pathania D, Park KS, Avila-Wallace M, Castro CM, Weissleder R, Lee H

Compact and Filter-Free Luminescence Biosensor for Mobile In-Vitro Diagnoses.
ACS Nano. 2019;13(10):11698-11706 - PMID: 31461265 - PMCID: PMC7307311 - DOI: 10.1021/acsnano.9b05634

Min J, Im H, Allen M, McFarland PJ, Degani I, Yu H, Normandin E, Pathania D, Patel J, Castro CM, Weissleder R, Lee H

Computational Optics Enables Breast Cancer Profiling in Point-Of-Care Settings.
ACS Nano. 2018;12(9):9081-9090 - PMID: 30113824 - PMCID: PMC6519708 - DOI: 10.1021/acsnano.8b03029

Min J, Nothing M, Coble B, Zheng H, Park J, Im H, Weber GF, Castro CM, Swirski FK, Weissleder R, Lee H

Integrated Biosensor for Rapid and Point-Of-Care Sepsis Diagnosis.
ACS Nano. 2018;12(4):3378-3384 - PMID: 29533646 - PMCID: PMC6019292 - DOI: 10.1021/acsnano.7b08965

Park K, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H

Nano-Magnetic System For Rapid Diagnosis Of Acute Infection.
ACS Nano. 2017;11(11):11425-11432 - PMID: 29121461 - PMCID: PMC6296367 - DOI: 10.1021/acsnano.7b06074

Park J, Lin HY, Assaker JP, Jeong S, Huang CH, Kurdi A, Lee K, Fraser K, Min C, Eskandari S, Routray S, Tannous BA, Abdi R, Riella L, Chandraker A, Castro CM, Weissleder R, Lee H, Azzi JR

Integrated Kidney Exosome Analysis (iKEA) For The Detection Of Kidney Transplant Rejection.
ACS Nano. 2017;11(11):11041-11046 - PMID: 29053921 - PMCID: PMC6237084 - DOI: 10.1021/acsnano.7b05083

Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H

Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection.
ACS Nano. 2017;11(10):10062-10069 - PMID: 28792732 - DOI: 10.1021/acsnano.7b04318

Jeong S, Park J, Pathania D, Castro CM, Weissleder R, Lee H

Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
ACS Nano. 2016;10(2):1802-1809 - PMID: 26808216 - PMCID: PMC4802494 - DOI: 10.1021/acsnano.5b07584

Lee K, Shao H, Weissleder R, Lee H

Acoustic Purification of Extracellular Microvesicles.
ACS Nano. 2015;9(3):2321-7 - PMID: 25672598 - PMCID: PMC4373978 - DOI: 10.1021/nn506538f

Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R

Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles.
ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727 - DOI: 10.1021/nn2029692

Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R

Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells.
ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118 - DOI: 10.1021/nn203450p

Haun J, Devaraj NK, Marinelli B, Lee H, Weissleder R

Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry.
ACS Nano. 2011;5(4):3204-13 - PMID: 21351804 - PMCID: PMC3088084 - DOI: 10.1021/nn200333m
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