Tozzo V, Nathan DM, Krause-Steinrauf H, Lachin JM, Mow C, Butera N, Cohen RM, Higgins JM, GRADE Research Group

Differences Between Glycemia Estimates from Hemoglobin A1c and Continuous Glucose Monitoring and Their Association with Complete Blood Counts.
Diabetes Technol Ther. 2025;28(5):490-500 - PMID: 41439332 - PMCID: PMC12970290 - DOI: 10.1177/15209156251395036

Malka R, Delgado FF, Manalis SR, Higgins JM

In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells.
PLoS Comput Biol. 2014;10(10):e1003839 - PMID: 25299941 - PMCID: PMC4191880 - DOI: 10.1371/journal.pcbi.1003839

Higgins JM, Eddington DT, Bhatia SN, Mahadevan L

Statistical dynamics of flowing red blood cells by morphological image processing.
PLoS Comput Biol. 2009;5(2):e1000288 - PMID: 19214200 - PMCID: PMC2631282 - DOI: 10.1371/journal.pcbi.1000288

Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR

Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells.
PLoS ONE. 2013;8(7):e67590 - PMID: 23844039 - PMCID: PMC3699654 - DOI: 10.1371/journal.pone.0067590

Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM

Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume.
Cytometry A. 2014;85(4):332-8 - PMID: 24677669 - PMCID: PMC4717472 - DOI: 10.1002/cyto.a.22450

Lu X, Wood DK, Higgins JM

Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension.
Biophys J. 2016;110(12):2751-8 - PMID: 27332133 - PMCID: PMC4919586 - DOI: 10.1016/j.bpj.2016.04.050

Perazzo A, Peng Z, Young YN, Feng Z, Wood DK, Higgins JM, Stone HA

The effect of rigid cells on blood viscosity: linking rheology and sickle cell anemia.
Soft Matter. 2022;18(3):554-565 - PMID: 34931640 - PMCID: PMC8925304 - DOI: 10.1039/d1sm01299a

Noiret L, Slater A, Higgins JM

Determinants of red blood cell alloantibody detection duration: analysis of multiply alloimmunized patients supports peritransfusion factors.
Transfusion. 2017;57(8):1930-1937 - PMID: 28639314 - DOI: 10.1111/trf.14157

Kim Y, Higgins JM, Dasari RR, Suresh S, Park Y

Anisotropic light scattering of individual sickle red blood cells.
J Biomed Opt. 2012;17(4):040501 - PMID: 22559667 - PMCID: PMC3602817 - DOI: 10.1117/1.JBO.17.4.040501

Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA

Computational pathology: an emerging definition.
Arch Pathol Lab Med. 2014;138(9):1133-8 - PMID: 25171694 - DOI: 10.5858/arpa.2014-0034-ED

Yonker LM, Badaki-Makun O, Alvarez-Carcamo B, Cross C, Okuducu Y, Appleman L, Greatorex J, Onu RE, Santos C, Petherbridge R, Foy BH, Cereaga D, Naiman M, Castro I, Haller L, Guthrie LB, Higgins JM, Lewandrowski KB, Irimia D

Monocyte Anisocytosis is Associated with Sepsis in Children with Suspected Infection.
Shock. 2024;63(3):385-389 - PMID: 39749928 - PMCID: PMC12450074 - DOI: 10.1097/SHK.0000000000002502

Lu X, Galarneau MM, Higgins JM, Wood DK

A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow.
Microcirculation. 2017;24(5):ePub - PMID: 28129479 - PMCID: PMC5505799 - DOI: 10.1111/micc.12357

Huck A, Pozdnyakova O, Brunner A, Higgins JM, Fathi AT, Hasserjian RP

Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia.
Leuk Res. 2015;39(10):1034-40 - PMID: 26220865 - PMCID: PMC5764101 - DOI: 10.1016/j.leukres.2015.06.012

Baron JM, Higgins JM, Dzik WH

A Revised Timeline for the Origin of Plasmodium falciparum as a Human Pathogen.
J Mol Evol. 2011;73(5-6):297-304 - PMID: 22183792 - DOI: 10.1007/s00239-011-9476-x

Higgins JM

Red Blood Cell Population Dynamics.
Clin Lab Med. 2014;35(1):43-57 - PMID: 25676371 - PMCID: PMC4717490 - DOI: 10.1016/j.cll.2014.10.002

Baron JM, Dighe AS, Arnaout R, Balis UJ, Black-Schaffer WS, Carter AB, Henricks WH, Higgins JM, Jackson BR, Kim J, Klepeis VE, Le LP, Louis DN, Mandelker D, Mermel CH, Michaelson JS, Nagarajan R, Platt ME, Quinn AM, Rao L, Shirts BH, Gilbertson JR

The 2013 symposium on pathology data integration and clinical decision support and the current state of field.
J Pathol Inform. 2014;5:2 - PMID: 24672737 - PMCID: PMC3952400 - DOI: 10.4103/2153-3539.126145

Foy BH, Sundt T, Carlson JCT, Aguirre AD, Higgins JM

White Blood Cell and Platelet Dynamics Define Human Inflammatory Recovery.
medRxiv. 2021;:ePub - PMID: 34189534 - PMCID: PMC8240689 - DOI: 10.1101/2021.06.19.21259181

Foy BH, Petherbridge R, Roth M, Mow C, Patel HR, Patel CH, Ho SN, Lam E, Karczewski KJ, Tozzo V, Higgins JM

Hematologic setpoints are a stable and patient-specific deep phenotype.
medRxiv. 2023;:ePub - PMID: 37808854 - PMCID: PMC10557837 - DOI: 10.1101/2023.09.26.23296146

Tozzo V, Petherbridge R, James K, Hsu S, Michalopoulos C, Foy BH, Thaweethai T, Mow C, Maya J, Camero CB, Shook L, Gray KJ, Mauney L, Higgins JM, Powe CE

Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study.
medRxiv. 2025;:ePub - PMID: 39990572 - PMCID: PMC11844592 - DOI: 10.1101/2025.02.13.25322250

Szafraniec HM, Bull F, Higgins JM, Stone HA, Krüger T, Pearce P, Wood DK

Suspension physics govern the multiscale dynamics of blood flow in sickle cell disease.
bioRxiv. 2025;:ePub - PMID: 40161781 - PMCID: PMC11952557 - DOI: 10.1101/2025.03.13.642599

Tozzo V, Zhang LH, Ranganath R, Higgins JM

Transformer-based artificial intelligence on single-cell clinical data for homeostatic mechanism inference and rational biomarker discovery.
medRxiv. 2025;:ePub - PMID: 40196278 - PMCID: PMC11974774 - DOI: 10.1101/2025.03.24.25324556

Williams DC, Higgins JM, Wood DK

Quantifying the unique mechanical properties of irreversibly sickled cells in sickle cell disease.
Blood Vessel Thromb Hemost. 2025;2(3):100077 - PMID: 40765910 - PMCID: PMC12320412 - DOI: 10.1016/j.bvth.2025.100077

Zhang LH, Tozzo V, Higgins JM, Ranganath R

Set Norm and Equivariant Skip Connections: Putting the Deep in Deep Sets.
Proc Mach Learn Res. 2022;162:26559-26574 - PMID: 37645424 - PMCID: PMC10465016

Foy BH, Carlson JCT, Reinertsen E, Padros I Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM

Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection.
JAMA Netw Open. 2020;3(9):e2022058 - PMID: 32965501 - PMCID: PMC7512057 - DOI: 10.1001/jamanetworkopen.2020.22058

Foy BH, Carlson JCT, Reinertsen E, Padros Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM

Elevated RDW is Associated with Increased Mortality Risk in COVID-19
medRxiv. 2020;:ePub - DOI: 10.1101/2020.05.05.20091702
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