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Ishida E, Lee J, Campbell JS, Chakravarty PD, Katori Y, Ogawa T, Johnson L, Mukhopadhyay A, Faquin WC, Lin DT, Wirth LJ, Pierce RH, Pai SI

Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model.
Cancer Immunol Immunother. 2019;68(8):1273-1286 - PMID: 31243491 - PMCID: PMC6684362 - DOI: 10.1007/s00262-019-02357-1

Wolkow N, Jakobiec FA, Afrogheh AH, Pai SI, Faquin WC

High Expression of Programmed Death Ligand 1 and Programmed Death Ligand 2 in Ophthalmic Sebaceous Carcinoma: The Case for a Clinical Trial of Checkpoint Inhibitors.
Am J Ophthalmol. 2020;220:128-139 - PMID: 32730911 - PMCID: PMC9361189 - DOI: 10.1016/j.ajo.2020.07.031

Wolkow N, Jakobiec FA, Afrogheh AH, Eagle RC, Pai SI, Faquin WC

Programmed Cell Death 1 Ligand 1 and Programmed Cell Death 1 Ligand 2 Are Expressed in Conjunctival Invasive Squamous Cell Carcinoma: Therapeutic Implications.
Am J Ophthalmol. 2019;200:226-241 - PMID: 30633894 - PMCID: PMC7456462 - DOI: 10.1016/j.ajo.2018.12.020

Wu AA, Niparko KJ, Pai SI

Immunotherapy for head and neck cancer.
J Biomed Sci. 2008;15(3):275-89 - PMID: 18392689 - DOI: 10.1007/s11373-008-9247-x

Rosenbaum MW, Gigliotti BJ, Pai SI, Parangi S, Wachtel H, Mino-Kenudson M, Gunda V, Faquin WC

PD-L1 and IDO1 Are Expressed in Poorly Differentiated Thyroid Carcinoma.
Endocr Pathol. 2018;29(1):59-67 - PMID: 29372535 - PMCID: PMC6500591 - DOI: 10.1007/s12022-018-9514-y

Tufano RP, Pai SI

Thyroid and parathyroid surgery. Preface.
Otolaryngol Clin North Am. 2010;43(2):xiii-xiv - PMID: 20510709 - DOI: 10.1016/j.otc.2010.04.001

Best SR, Niparko KJ, Pai SI

Biology of human papillomavirus infection and immune therapy for HPV-related head and neck cancers.
Otolaryngol Clin North Am. 2012;45(4):807-22 - PMID: 22793854 - PMCID: PMC3398423 - DOI: 10.1016/j.otc.2012.04.005

Pai SI, Tufano RP

Central compartment neck dissection for thyroid cancer. Technical considerations.
ORL J Otorhinolaryngol Relat Spec. 2008;70(5):292-7 - PMID: 18971593 - DOI: 10.1159/000149831

Gooi Z, Ward BK, Mener DJ, Ozgursoy OB, Pai SI

A staged thyroidectomy approach for gastric bypass patients.
Laryngoscope. 2014;125(4):1028-30 - PMID: 25043176 - DOI: 10.1002/lary.24835

Kartha VK, Alamoud KA, Sadykov K, Nguyen BC, Laroche F, Feng H, Lee J, Pai SI, Varelas X, Egloff AM, Snyder-Cappione JE, Belkina AC, Bais MV, Monti S, Kukuruzinska MA

Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer.
Genome Med. 2018;10(1):54 - PMID: 30029671 - PMCID: PMC6053793 - DOI: 10.1186/s13073-018-0569-7

Mohan S, Pai SI, Bhattacharyya N

Adjuvant radiotherapy is not supported in patients with verrucous carcinoma of the oral cavity.
Laryngoscope. 2017;127(6):1334-1338 - PMID: 28150306 - PMCID: PMC7388729 - DOI: 10.1002/lary.26443

Bishop JA, Guo TW, Smith DF, Wang H, Ogawa T, Pai SI, Westra WH

Human papillomavirus-related carcinomas of the sinonasal tract.
Am J Surg Pathol. 2013;37(2):185-92 - PMID: 23095507 - PMCID: PMC3545097 - DOI: 10.1097/PAS.0b013e3182698673

Ahn J, Bishop JA, Akpeng B, Pai SI, Best SR

Xenograft model for therapeutic drug testing in recurrent respiratory papillomatosis.
Ann Otol Rhinol Laryngol. 2014;124(2):110-5 - PMID: 25124839 - PMCID: PMC7423457 - DOI: 10.1177/0003489414546400

Gleber-Netto FO, Zhao M, Trivedi S, Wang J, Jasser S, McDowell C, Kadara H, Zhang J, Wang J, William WN, Lee JJ, Nguyen ML, Pai SI, Walline HM, Shin DM, Ferris RL, Carey TE, Myers JN, Pickering CR, Head and Neck Cancer Specialized Program of Research Excellence (SPORE) Human Immunodeficiency Virus (HIV) Supplement Consortium

Distinct pattern of TP53 mutations in human immunodeficiency virus-related head and neck squamous cell carcinoma.
Cancer. 2017;124(1):84-94 - PMID: 29053175 - PMCID: PMC5785080 - DOI: 10.1002/cncr.31063

Zhang H, Kim S, Chen Z, Nannapaneni S, Chen AY, Moore CE, Sica G, Mosunjac M, Nguyen MLT, D'Souza G, Carey TE, Peterson LA, McHugh JB, Graham M, Komarck CM, Wolf GT, Walline HM, Bellile E, Riddell J, Pai SI, Sidransky D, Westra WH, William WN, Lee JJ, El-Naggar AK, Ferris RL, Seethala R, Grandis JR, Chen ZG, Saba NF, Shin DM, Head and Neck Cancer SPORE HIV supplement consortium

Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma.
Head Neck. 2017;39(12):2433-2443 - PMID: 28945296 - PMCID: PMC5808949 - DOI: 10.1002/hed.24911

Pai SI

Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma.
OncoImmunology. 2013;2(5):e24065 - PMID: 23762795 - PMCID: PMC3667901 - DOI: 10.4161/onci.24065

Dʼsouza G, Carey TE, William WN, Nguyen ML, Ko EC, Riddell J, Pai SI, Gupta V, Walline HM, Lee JJ, Wolf GT, Shin DM, Grandis JR, Ferris RL

Epidemiology of head and neck squamous cell cancer among HIV-infected patients.
J Acquir Immune Defic Syndr. 2014;65(5):603-10 - PMID: 24326607 - PMCID: PMC3999230 - DOI: 10.1097/QAI.0000000000000083

Pai SI, Wirth LJ

Checkpoint cluster: biomarkers of response.
Emerg Top Life Sci. 2017;1(5):501-508 - PMID: 33525795 - DOI: 10.1042/ETLS20170077

Peng S, Mattox A, Best SR, Barbu AM, Burns JA, Akpeng B, Jeang J, Yang B, Ishida E, Hung CF, Wu TC, Pai SI

Identification of the murine H-2D(b) and human HLA-A*0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes.
Cancer Immunol Immunother. 2016;65(3):261-71 - PMID: 26759151 - PMCID: PMC5690558 - DOI: 10.1007/s00262-016-1793-x

Walline HM, Carey TE, Goudsmit CM, Bellile EL, D'Souza G, Peterson LA, McHugh JB, Pai SI, Lee JJ, Shin DM, Ferris RL, HNC SPORE HIV supplement consortium

High-Risk HPV, Biomarkers, and Outcome in Matched Cohorts of Head and Neck Cancer Patients Positive and Negative for HIV.
Mol Cancer Res. 2016;15(2):179-188 - PMID: 27899422 - PMCID: PMC5290187 - DOI: 10.1158/1541-7786.MCR-16-0255

Lin BM, Wang H, D'Souza G, Zhang Z, Fakhry C, Joseph AW, Drake VE, Sanguineti G, Westra WH, Pai SI

Long-term prognosis and risk factors among patients with HPV-associated oropharyngeal squamous cell carcinoma.
Cancer. 2013;119(19):3462-71 - PMID: 23861037 - PMCID: PMC3788050 - DOI: 10.1002/cncr.28250

Lyford-Pike S, Westra WH, Loyo M, Peng S, Hung CF, Wu AA, Flint PW, Tunkel DE, Saunders JR, Pai SI

Differential expression of epidermal growth factor receptor in juvenile and adult-onset recurrent respiratory papillomatosis.
Histopathology. 2010;57(5):768-70 - PMID: 21083608 - DOI: 10.1111/j.1365-2559.2010.03691.x

Wu G, Pai SI, Agrawal N, Richmon J, Dackiw A, Tufano RP

Profile of patients with completion thyroidectomy and assessment of their suitability for outpatient surgery.
Otolaryngol Head Neck Surg. 2011;145(5):727-31 - PMID: 21860058 - DOI: 10.1177/0194599811416749

Cho YG, Chang X, Park IS, Yamashita K, Shao C, Ha PK, Pai SI, Sidransky D, Kim MS

Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma.
Int J Oncol. 2011;39(2):337-44 - PMID: 21617854 - PMCID: PMC3601031 - DOI: 10.3892/ijo.2011.1050

Anderson KS, Wong J, D'Souza G, Riemer AB, Lorch J, Haddad R, Pai SI, Longtine J, McClean M, LaBaer J, Kelsey KT, Posner M

Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer.
Br J Cancer. 2011;104(12):1896-905 - PMID: 21654689 - PMCID: PMC3111202 - DOI: 10.1038/bjc.2011.171

Tsen SW, Wu CY, Meneshian A, Pai SI, Hung CF, Wu TC

Femtosecond laser treatment enhances DNA transfection efficiency in vivo.
J Biomed Sci. 2009;16:36 - PMID: 19338665 - PMCID: PMC2669473 - DOI: 10.1186/1423-0127-16-36

Loyo M, Pai SI, Netto GJ, Tunkel DE

Aggressive recurrent respiratory papillomatosis in a neonate.
Int J Pediatr Otorhinolaryngol. 2008;72(6):917-20 - PMID: 18423627 - DOI: 10.1016/j.ijporl.2008.02.022

Peng S, Best SR, Hung CF, Loyo M, Lyford-Pike S, Flint PW, Tunkel DE, Saunders JR, Wu TC, Pai SI

Characterization of human papillomavirus type 11-specific immune responses in a preclinical model.
Laryngoscope. 2010;120(3):504-10 - PMID: 20025042 - PMCID: PMC2908018 - DOI: 10.1002/lary.20745

Sedaghat AR, Zhang Z, Begum S, Palermo R, Best S, Ulmer KM, Levine M, Zinreich E, Messing BP, Gold D, Wu AA, Niparko KJ, Kowalski J, Hirata RM, Saunders JR, Westra WH, Pai SI

Prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinomas.
Laryngoscope. 2009;119(8):1542-9 - PMID: 19522004 - DOI: 10.1002/lary.20533

Peng S, Lyford-Pike S, Akpeng B, Wu A, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI

Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine.
Cancer Immunol Immunother. 2012;62(1):171-82 - PMID: 23011589 - PMCID: PMC3543472 - DOI: 10.1007/s00262-012-1322-5

Kim D, Hoory T, Monie A, Wu A, Hsueh WT, Pai SI, Hung CF

Delivery of chemotherapeutic agents using drug-loaded irradiated tumor cells to treat murine ovarian tumors.
J Biomed Sci. 2010;17:61 - PMID: 20659328 - PMCID: PMC2918546 - DOI: 10.1186/1423-0127-17-61

Jara SM, Carson KA, Pai SI, Agrawal N, Richmon JD, Prescott JD, Dackiw A, Zeiger MA, Bishop JA, Tufano RP

The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma.
Surgery. 2013;154(6):1272-80; discussion 1280-2 - PMID: 24238047 - DOI: 10.1016/j.surg.2013.07.021

Bishop JA, Ogawa T, Stelow EB, Moskaluk CA, Koch WM, Pai SI, Westra WH

Human papillomavirus-related carcinoma with adenoid cystic-like features: a peculiar variant of head and neck cancer restricted to the sinonasal tract.
Am J Surg Pathol. 2013;37(6):836-44 - PMID: 23598962 - PMCID: PMC3653997 - DOI: 10.1097/PAS.0b013e31827b1cd6

Park IS, Chang X, Loyo M, Wu G, Chuang A, Kim MS, Chae YK, Lyford-Pike S, Westra WH, Saunders JR, Sidransky D, Pai SI

Characterization of the methylation patterns in human papillomavirus type 16 viral DNA in head and neck cancers.
Cancer Prev Res (Phila). 2011;4(2):207-17 - PMID: 21292634 - PMCID: PMC3079312 - DOI: 10.1158/1940-6207.CAPR-10-0147

Flint PW, Li ZB, Lehar M, Saito K, Pai SI

Laryngeal muscle surface receptors identified using random phage library.
Laryngoscope. 2005;115(11):1930-7 - PMID: 16319601 - DOI: 10.1097/01.mlg.0000172273.98418.8d

Bishop JA, Ogawa T, Chang X, Illei PB, Gabrielson E, Pai SI, Westra WH

HPV analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma.
Am J Surg Pathol. 2012;36(1):142-8 - PMID: 22173119 - PMCID: PMC3273906 - DOI: 10.1097/PAS.0b013e3182395c7b

Best SR, Ha PK, Blanco RG, Saunders JR, Zinreich ES, Levine MA, Pai SI, Walker M, Trachta J, Ulmer K, Murakami P, Thompson R, Califano JA, Messing BP

Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.
Head Neck. 2011;33(12):1727-34 - PMID: 21246640 - PMCID: PMC4695991 - DOI: 10.1002/hed.21657

Wu G, Fraser S, Pai SI, Farrag TY, Ladenson PW, Tufano RP

Determining the extent of lateral neck dissection necessary to establish regional disease control and avoid reoperation after previous total thyroidectomy and radioactive iodine for papillary thyroid cancer.
Head Neck. 2011;34(10):1418-21 - PMID: 22052539 - DOI: 10.1002/hed.21937

Hillel AT, Fakhry C, Pai SI, Williams MF, Blanco RG, Zinreich ES, Levine MA, Westra WH, Saunders JR, Ha PK

Selective versus comprehensive neck dissection after chemoradiation for advanced oropharyngeal squamous cell carcinoma.
Otolaryngol Head Neck Surg. 2009;141(6):737-42 - PMID: 19932847 - DOI: 10.1016/j.otohns.2009.09.010

Goldenberg D, Begum S, Westra WH, Khan Z, Sciubba J, Pai SI, Califano JA, Tufano RP, Koch WM

Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon.
Head Neck. 2008;30(7):898-903 - PMID: 18383529 - DOI: 10.1002/hed.20796

Kim TW, Hung CF, Zheng M, Boyd DA, He L, Pai SI, Wu TC

A DNA vaccine co-expressing antigen and an anti-apoptotic molecule further enhances the antigen-specific CD8+ T-cell immune response.
J Biomed Sci. 2004;11(4):493-9 - PMID: 15153784 - DOI: 10.1007/BF02256098

Dong SM, Pai SI, Rha SH, Hildesheim A, Kurman RJ, Schwartz PE, Mortel R, McGowan L, Greenberg MD, Barnes WA, Sidransky D

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma.
Cancer Epidemiol Biomarkers Prev. 2002;11(1):3-6 - PMID: 11815394

Cheng WF, Hung CF, Pai SI, Hsu KF, He L, Ling M, Wu TC

Repeated DNA vaccinations elicited qualitatively different cytotoxic T lymphocytes and improved protective antitumor effects.
J Biomed Sci. 2002;9(6 Pt 2):675-87 - PMID: 12432234 - DOI: 10.1159/000067285

Pai SI, Limb CJ, Nicol T, Williams MF

Leiomyosarcoma of the auricle.
Otolaryngol Head Neck Surg. 2003;128(3):442-4 - PMID: 12646855 - DOI: 10.1067/mhn.2003.16

Lin LM, Pai SI, Flint PW

A retropharyngeal pseudoabscess in a patient with paroxysmal nocturnal hemoglobinuria.
Otolaryngol Head Neck Surg. 2007;137(4):684-6 - PMID: 17903595 - DOI: 10.1016/j.otohns.2007.01.032

Nichols RC, Blinder J, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P

Assignment of two human autoantigen genes-isoleucyl-tRNA synthetase locates to 9q21 and lysyl-tRNA synthetase locates to 16q23-q24.
Genomics. 1996;36(1):210-3 - PMID: 8812440 - DOI: 10.1006/geno.1996.0449

Nichols RC, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P

Localization of two human autoantigen genes by PCR screening and in situ hybridization--glycyl-tRNA synthetase locates to 7p15 and alanyl-tRNA synthetase locates to 16q22.
Genomics. 1995;30(1):131-2 - PMID: 8595897 - DOI: 10.1006/geno.1995.0028

Pai SI, Goldstein BJ, Studeman KD, Westra WH, Tufano RP

Concurrent sporadic parathyroid adenoma and carcinoma.
Am J Otolaryngol. 2006;27(5):346-8 - PMID: 16935182 - DOI: 10.1016/j.amjoto.2005.11.017

Friedmann AS, Malott KA, Memoli VA, Pai SI, Yu XM, North WG

Products of vasopressin gene expression in small-cell carcinoma of the lung.
Br J Cancer. 1994;69(2):260-3 - PMID: 8297723 - PMCID: PMC1968694 - DOI: 10.1038/bjc.1994.49

Deyell M, Garris CS, Laughney AM

Cancer metastasis as a non-healing wound.
Br J Cancer. 2021;124(9):1491-1502 - PMID: 33731858 - PMCID: PMC8076293 - DOI: 10.1038/s41416-021-01309-w
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