Structural origin of selectivity in class II-selective histone deacetylase inhibitors.
J Med Chem. 2008;51:2898-906 - PMID: 18412327 - DOI: 10.1021/jm7015254
Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum.
Highly Efficient Activatable MRI Probe to Sense Myeloperoxidase Activity.
J Med Chem. 2021;64(9):5874-5885 - PMID: 33945286 - PMCID: PMC8564765 - DOI: 10.1021/acs.jmedchem.1c00038
In Vivo PET-imaging of Histone Deacetylases by 18F-Suberoylanilide Hydroxamic Acid (18F-SAHA).
Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold.
J Med Chem. 2003;46(14):2917-31 - PMID: 12825933 - DOI: 10.1021/jm0307943
MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo.
Int J Cancer. 2004;112(6):986-93 - PMID: 15386354 - DOI: 10.1002/ijc.20509
In vivo assessment of vascular endothelial growth factor-induced angiogenesis
Int J Cancer. 1999;83:798-802 - PMID: 10597197 - DOI: 10.1002/(sici)1097-0215(19991210)83:6<798::aid-ijc16>3.0.co;2-w
A novel mouse model for segmental orthotopic colon cancer
Int J Cancer. 2005;117(3):335-9 - PMID: 15900588 - DOI: 10.1002/ijc.21185
Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer.
Int J Cancer. 2006;118(11):2672-7 - PMID: 16380983 - DOI: 10.1002/ijc.21713
Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment.
Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072 - DOI: 10.1002/ijc.22995
Eurogin Roadmap 2015: How has HPV knowledge changed our practice: Vaccines.
Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection.
Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - DOI: 10.1111/j.1600-6143.2007.01757.x
Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells.
Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922 - DOI: 10.1111/j.1600-6143.2010.03089.x
Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity.
Am J Transplant. 2010;11(2):348-355 - PMID: 21182586 - DOI: 10.1111/j.1600-6143.2010.03360.x
Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study.
Multimodal Molecular Imaging Demonstrates Myeloperoxidase Regulation of Matrix Metalloproteinase Activity in Neuroinflammation.
Mol Neurobiol. 2018;56(2):954-962 - PMID: 29808380 - PMCID: PMC6261713 - DOI: 10.1007/s12035-018-1137-2
An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis.
Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884 - DOI: 10.1038/modpathol.2015.105
Consensus statement on the pathology of IgG4-related disease.
Mod Pathol. 2012;25(9):1181-92 - PMID: 22596100 - DOI: 10.1038/modpathol.2012.72
A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy.
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors.
Chem Biol. 2011;18(12):1602-10 - PMID: 22195562 - PMCID: PMC3474356 - DOI: 10.1016/j.chembiol.2011.09.016
A robust small-molecule microarray platform for screening cell lysates.
Chem Biol. 2006;13(5):493-504 - PMID: 16720270 - DOI: 10.1016/j.chembiol.2006.03.004
Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter.
Chem Biol. 2004;11(1):99-106 - PMID: 15112999 - DOI: 10.1016/j.chembiol.2003.12.017
Covalent Reactions of Wortmannin under Physiological Conditions.
Chem Biol. 2007;14(3):321-8 - PMID: 17379147 - DOI: 10.1016/j.chembiol.2007.02.007
A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages.
Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040 - DOI: 10.1016/j.chembiol.2007.10.005
Non-Invasive Optical Detection of Bone Mineral.
J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196 - DOI: 10.1359/jbmr.070504
Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone-resistance due to heterozygous Gαs disruption.
Hormonal regulation of osteocyte perilacunar and canalicular remodeling in the Hyp mouse model of XLH.
Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo.
Thromb Haemostasis. 2011;105(5):828-36 - PMID: 21225096 - PMCID: PMC3087830 - DOI: 10.1160/TH10-09-0589
Video kinematics of an unloaded, ex-vivo beating heart can predict future loaded heart function.
J Heart Lung Transplant. 2025;44(11):1823-1826 - PMID: 40716473 - PMCID: PMC12862873 - DOI: 10.1016/j.healun.2025.07.023
Targeted imaging of myocardial damage.
Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115
Advances in measuring single-cell pharmacokinetics and pharmacology in vivo.
Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932 - DOI: 10.1016/j.drudis.2015.05.011
Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology
Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357
Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction.
ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9.
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering.
Basic Res Cardiol. 2020;115(6):78 - PMID: 33296022 - PMCID: PMC7725697 - DOI: 10.1007/s00395-020-00838-4
Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression.
Basic Res Cardiol. 2016;111(2):20 - PMID: 26891724 - PMCID: PMC4759214 - DOI: 10.1007/s00395-016-0535-8
Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.
Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7
MR-optical imaging of cardiovascular molecular targets.
Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2
Cardiovascular Risk Assessment Using Artificial Intelligence-Enabled Event Adjudication and Hematologic Predictors.
Circ Cardiovasc Qual Outcomes. 2022;15(6):e008007 - PMID: 35477255 - PMCID: PMC9208816 - DOI: 10.1161/CIRCOUTCOMES.121.008007
Novel role of proton-secreting epithelial cells in sperm maturation and mucosal immunity.
A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819 - DOI: 10.1242/jcs.046813
HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions.
J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687 - DOI: 10.1242/jcs.03431
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway.
Direct interaction of ezrin and AQP2 and its role in AQP2 trafficking.
FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience.
Oncologist. 2013;18(5):543-548 - PMID: 23657686 - PMCID: PMC3662845 - DOI: 10.1634/theoncologist.2012-0435
Developing a Roadmap for Interventional Oncology.
Oncologist. 2018;23(10):1162-1170 - PMID: 29959284 - PMCID: PMC6263130 - DOI: 10.1634/theoncologist.2017-0654
Ocular Effects of MEK Inhibitor Therapy: Literature Review, Clinical Presentation, and Best Practices for Mitigation.
Oncologist. 2024;29(5):e616-e621 - PMID: 38527005 - PMCID: PMC11067803 - DOI: 10.1093/oncolo/oyae014
Cells and Iron Oxide Nanoparticles on the Move: Magnetic Resonance Imaging of Monocyte Homing and Myocardial Inflammation in Patients With ST-Elevation Myocardial Infarction.
Circ Cardiovasc Imaging. 2012;5(5):551-4 - PMID: 22991284 - PMCID: PMC3529959 - DOI: 10.1161/CIRCIMAGING.112.978932
Fluorescence Tomography of Rapamycin-Induced Autophagy and Cardioprotection In Vivo.
Circ Cardiovasc Imaging. 2013;6(3):441-7 - PMID: 23537953 - PMCID: PMC3805276 - DOI: 10.1161/CIRCIMAGING.112.000074