Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM.
Clin Cancer Res. 2017;24(1):197-208 - PMID: 29051323 - PMCID: PMC5959009 - DOI: 10.1158/1078-0432.CCR-17-1577
Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma.
Clin Cancer Res. 2017;23(19):5959-5969 - PMID: 28600474 - PMCID: PMC5856249 - DOI: 10.1158/1078-0432.CCR-17-0256
PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.
Clin Cancer Res. 2011;17(11):3638-48 - PMID: 21459800 - PMCID: PMC3107920 - DOI: 10.1158/1078-0432.CCR-10-2456
The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA-Mutant Breast Cancer Brain Metastases.
Clin Cancer Res. 2019;25(11):3374-3383 - PMID: 30796030 - PMCID: PMC6685218 - DOI: 10.1158/1078-0432.CCR-18-3049
Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma.
Clin Cancer Res. 2020;26(12):2827-2837 - PMID: 32376655 - PMCID: PMC9354653 - DOI: 10.1158/1078-0432.CCR-19-2217
TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas.
Clin Cancer Res. 2020;27(1):169-178 - PMID: 33051308 - PMCID: PMC7785705 - DOI: 10.1158/1078-0432.CCR-20-3083
Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors.
Clin Cancer Res. 2013;20(3):644-57 - PMID: 24300786 - PMCID: PMC3946442 - DOI: 10.1158/1078-0432.CCR-13-1334
Combination of viral oncolysis and tumor-specific immunity to control established tumors.
Clin Cancer Res. 2009;15(14):4581-8 - PMID: 19584165 - PMCID: PMC3076709 - DOI: 10.1158/1078-0432.CCR-08-2685
Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity.
Clin Cancer Res. 2002;8(5):1203-9 - PMID: 12006539
Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma.
Clin Cancer Res. 2000;6(11):4171-5 - PMID: 11106228
Dendritic Cells, the T-cell-inflamed Tumor Microenvironment, and Immunotherapy Treatment Response.
Clin Cancer Res. 2020;26(15):3901-3907 - PMID: 32332013 - PMCID: PMC7607412 - DOI: 10.1158/1078-0432.CCR-19-1321
Rapid serial immunoprofiling of the tumor immune microenvironment by fine needle sampling
Clin Cancer Res. 2021;27(17):4781-4793 - PMID: 34233961 - PMCID: PMC8416923 - DOI: 10.1158/1078-0432.CCR-21-1252
Refining the Molecular Framework for Pancreatic Cancer with Single-cell and Spatial Technologies.
Clin Cancer Res. 2021;27(14):3825-3833 - PMID: 33653818 - PMCID: PMC8282742 - DOI: 10.1158/1078-0432.CCR-20-4712
Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection.
Clin Cancer Res. 2021;27(10):2807-2815 - PMID: 33632928 - PMCID: PMC8127360 - DOI: 10.1158/1078-0432.CCR-20-4382
Thyroid cancers exhibit oncogene-enhanced macropinocytosis that is restrained by IGF1R and promotes albumin-drug-conjugate response.
Clin Cancer Res. 2023;29(17):3457-3470 - PMID: 37289199 - PMCID: PMC10527034 - DOI: 10.1158/1078-0432.CCR-22-2976
Therapeutic Targeting of Epithelial Mesenchymal Cellular Plasticity in Pancreatic Cancer.
Clin Cancer Res. 2025;:ePub - PMID: 41364739 - DOI: 10.1158/1078-0432.CCR-25-2052
Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging.
Clin Cancer Res. 2011;17(13):4484-93 - PMID: 21558403 - PMCID: PMC3131449 - DOI: 10.1158/1078-0432.CCR-11-0575
Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor.
Clin Cancer Res. 2008;14(22):7340-7 - PMID: 19010849 - PMCID: PMC2744414 - DOI: 10.1158/1078-0432.CCR-08-0642
Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040).
J Immunother Cancer. 2019;7(1):96 - PMID: 30944020 - PMCID: PMC6446400 - DOI: 10.1186/s40425-019-0578-0
Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee.
J Immunother Cancer. 2020;8(2):ePub - PMID: 33199512 - PMCID: PMC7670953 - DOI: 10.1136/jitc-2020-001583
Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop.
J Immunother Cancer. 2023;11(6):ePub - PMID: 37290925 - PMCID: PMC10254706 - DOI: 10.1136/jitc-2023-006773
Jarid2 and PRC2, partners in regulating gene expression.
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.
The Arabidopsis kinase-associated protein phosphatase controls internalization of the somatic embryogenesis receptor kinase 1.
BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo.
Small Molecule Imaging Agent for Mutant KRAS G12C
Advanced Therapeutics. 2021;:2000290 - DOI: 10.1002/adtp.202000290
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages
Delivery of miR-146a to Ly6Chigh Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis.
Bioassay for monitoring the anti-aging effect of cord blood treatment.
Point-of-care cervical cancer screening using deep learning-based microholography
Understanding the EPR effect through image-guided systems pharmacology
Theranostics. 2019;:ePub
Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy
Screening for new macrophage therapeutics.
A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales.
Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma.
Theranostics. 2022;12(5):1988-1998 - PMID: 35265194 - PMCID: PMC8899565 - DOI: 10.7150/thno.69094 - Cover
Upconverting Organic Dye Doped Core-Shell Nano-Composites for Dual-Modality NIR Imaging and Photo-Thermal Therapy.
Molecular Imaging of Inflammation in Atherosclerosis.
Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System
Theranostics. 2014;4(11):1133-1144
On chip analysis of CNS lymphoma in cerebrospinal fluid.
Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.
Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging.
Polymeric microneedles enable simultaneous delivery of cancer immunomodulatory drugs and detection of skin biomarkers.
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation.
Lipid Nanoparticle-mRNA Engineered Dendritic Cell Based Adoptive Cell Therapy Enhances Cancer Immune Response.
Small Methods. 2024;9(1):e2400633 - PMID: 39039995 - PMCID: PMC11740962 - DOI: 10.1002/smtd.202400633
A specific and adaptable approach to track CD206+ macrophages by molecular MRI and fluorescence imaging.
Magnetic Nanoparticles and microNMR for Diagnostic Applications.
Regulation and consequences of monocytosis.
Regulation of T Cell Migration and Effector Functions-Insights from in Vivo Imaging Studies
Immunol Rev. 2007;:ePub