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Payne NC, Kalyakina AS, Singh K, Tye MA, Mazitschek R
Bright and stable luminescent probes for target engagement profiling in live cells.
Nat Chem Biol. 2021;17(11):1168-1177 - PMID: 34675420 - PMCID: PMC8555866 - DOI: 10.1038/s41589-021-00877-5
Poli V, Pui-Yan Ma V, Di Gioia M, Broggi A, Benamar M, Chen Q, Mazitschek R, Haggarty SJ, Chatila TA, Karp JM, Zanoni I
Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation.
iScience. 2021;24(11):103256 - PMID: 34761180 - PMCID: PMC8567386 - DOI: 10.1016/j.isci.2021.103256
El-Awady R, Saleh E, Hamoudi R, Ramadan WS, Mazitschek R, Nael MA, Elokely KM, Abou-Gharbia M, Childers WE, Srinivasulu V, Aloum L, Menon V, Al-Tel TH
Discovery of novel class of histone deacetylase inhibitors as potential anticancer agents.
Bioorg Med Chem. 2021;42:116251 - PMID: 34116381 - DOI: 10.1016/j.bmc.2021.116251
Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM
The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.
bioRxiv. 2021;:ePub - PMID: 33791697 - PMCID: PMC8010724 - DOI: 10.1101/2021.03.22.436522
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