Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.
Proc Natl Acad Sci U S A. 2020;117(16):8900-8911 - PMID: 32253314 - PMCID: PMC7183223 - DOI: 10.1073/pnas.1913788117
Antifungal activity of gepinacin-scaffold GPI anchor biosynthesis inhibitors with improved metabolic stability.
Antimicrob Agents Chemother. 2020;64(10):ePub - PMID: 32661007 - PMCID: PMC7508603 - DOI: 10.1128/AAC.00899-20
Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation.
ACS Chem Biol. 2020;15(6):1445-1454 - PMID: 32338864 - PMCID: PMC7995447 - DOI: 10.1021/acschembio.0c00104
Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma.
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