Weissleder, Ralph, MD, PhD
Dr. Weissleder is the Thrall Professor of Radiology and Professor of Systems Biology at Harvard Medical School, Director of the Center for Systems Biology at Massachusetts General Hospital (MGH), Attending Clinician (Interventional Radiology) at MGH, senior faculty in the HMS Department of Systems Biology, a member of the Harvard Cancer Center as well as the Harvard Stem Cell Institute (HSCI). Dr. Weissleder obtained his postdoctoral and residency training at MGH (1986-91) and has been on faculty at HMS since 1991. He has published over 600 publications in peer reviewed journals and has authored several textbooks. His work has been honored with numerous awards including the J. Taylor International Prize in Medicine, the Millenium Pharmaceuticals Innovator Award, the AUR Memorial Award, the ARRS President's Award, The Society for Molecular Imaging Lifetime Achievement Award, the Academy of Molecular Imaging 2006 Distinguished Basic Scientist Award among others. In 2009 he was elected member of the US National Academies Institute of Medicine. His lab has been a driving force in studying human biology, especially cancer and inflammatory diseases. He has developed systematic ways to explore disease biology using in vivo imaging and has been instrumental in translating several discoveries into new drugs.
Imaging macrophages with nanoparticles.
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;:ePub - PMID: 24752081
Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity.
Circulation. 2014;129(16):1677-87 - PMID: 24488984
Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium.
Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates
Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut.
Proc Natl Acad Sci U S A. 2014;:ePub - PMID: 24753589
Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance.
Red Si-rhodamine drug conjugates enable imaging in GFP cells.
Chem Commun. 2014;50(34):4504-7 - PMID: 24663433
Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors.
Advanced Motion Compensation Methods for Intravital Optical Microscopy.
Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells.
Platinum Compounds for High-Resolution In Vivo Cancer Imaging.
ChemMedChem. 2014;:ePub - PMID: 24504646
Automated motion artifact removal for intravital microscopy, without a priori information.
Modelling and predicting the biological effects of nanomaterials.
SAR QSAR Environ Res. 2014;25(2):161-72 - PMID: 24625316
Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
Adv Healthc Mater. 2014;:ePub - PMID: 24532323
Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis