Miller, Miles , PhD
Miles Miller received his A.B. in Chemistry from Princeton University, and his Ph.D. in Biological Engineering from the Massachusetts Institute of Technology (Advisors: Douglas Lauffenburger and Linda Griffith). He trained as a NIH postdoctoral fellow under Dr. Ralph Weissleder at MGH. He specializes in parsing mechanisms of cell signaling and drug action from a quantitative network-level perspective, with training in computational modeling, imaging, nanotechnology, cell signaling biology, and drug delivery.
Imaging of anticancer drug action in single cells
Nat Rev Cancer. 2017;17(7):399–414 - PMID: 28642603
Richer data with personalized GEMs.
Sci Transl Med. 2017;9(381):ePub - PMID: 28298424
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts
Sci Transl Med. 2017;9(392):eaal0225 - PMID: 28566423
Nanoparticles improve economic mileage for CARs.
Sci Transl Med. 2017;9(387):ePub - PMID: 28446684
Driver mutations take the wheel in invasive yet nonmalignant disease.
Sci Transl Med. 2017;9(393):ePub - PMID: 28592567
In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging.
Nano-palladium is a cellular catalyst for in vivo chemistry
Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.
Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.
Methods Mol Biol. 2017;1574:243-253 - PMID: 28315256
Prediction of Anti-cancer Nanotherapy Efficacy by Imaging