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Gupta A, Das R, Reed K, Jeon T, Nguyen QTC, Rudra A, Ge X, Trongjit S, Vanrobaeys YS, Langer R, Weissleder R, Garris C, Anderson DG

Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models.
Nat Biotechnol. 2026;:ePub - PMID: 42129506 - PMCID: PMC13242704 - DOI: 10.1038/s41587-026-03115-2

Kim HS, Oh J, Jeon J, Fei F, Parvanian S, Kohler R, Garris C, Weissleder R

A ribonucleotide carbohydrate system (iRNC) enhances antigen presentation and controls glioblastoma.
Theranostics. 2026;16(8):3912-3927 - PMID: 41695470 - PMCID: PMC12905671 - DOI: 10.7150/thno.127558

Nguyen YTM, Pfefferlé M, Oh J, Simpson GG, Walker SA, Noguchi S, Garris CS, Deutsch-Williams RJ, Wirapati P, De Stefano F, Goemans M, Dai R, Vinegoni C, Fernández Del Castillo C, Liss AS, Pittet MJ, Weissleder R

Driving tumor-associated macrophages to a CXCL9Hi/SPP1Low phenotype eliminates pancreatic cancer.
Cell Rep Med. 2026;:102938 - PMID: 42492520 - DOI: 10.1016/j.xcrm.2026.102938
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