Biomedical Engneering

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Yang KS*, Im H*, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R
Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy
Sci Transl Med. 2017;9(391):eaal3226 - PMID: 28539469
Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H
Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection.
ACS Nano. 2017;:ePub - PMID: 28792732
Im H, Lee K, Weissleder R, Lee H, Castro CM
Novel nanosensing technologies for exosome detection and profiling.
Lab Chip. 2017;17(17):2892-2898 - PMID: 28745363 - PMCID: PMC5572557
Park YI, Kim E, Huang CH, Park KS, Castro CM, Lee H, Weissleder R
Facile Coating Strategy to Functionalize Inorganic Nanoparticles for Biosensing
Bioconjug Chem. 2017;28(1):33-37 - PMID: 27792877 - PMCID: PMC5474933
Im H, Yang K, Lee H, Castro CM
Characterization of Extracellular Vesicles by Surface Plasmon Resonance.
Methods Mol Biol. 2017;1660:133-141 - PMID: 28828653
Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR
Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer.
Sci Adv. 2017;3(6):e1700341 - PMID: 28630930 - PMCID: PMC5473678
Jeong S, Park J, Pathania D, Castro CM, Weissleder R, Lee H
Integrated Magneto-Electrochemical Sensor for Exosome Analysis.
ACS Nano. 2016;10(2):1802-1809 - PMID: 26808216 - PMCID: PMC4802494
Pathania D*, Im H*, Kilcoyne A, Sohani AR, Fexon L, Pivovarov M, Abramson JS, Randall TC, Chabner BA, Weissleder R, Lee H, Castro CM
Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications
Theranostics. 2016;6(10):1603-10 - PMID: 27446494 - PMCID: PMC4955059
Im H, Park YI, Pathania D, Castro CM, Weissleder R, Lee H
Digital diffraction detection of protein markers for avian influenza.
Lab Chip. 2016;16(8):1340-5 - PMID: 26980325 - PMCID: PMC4829473
Song J, Leon Swisher C, Im H, Jeong S, Pathania D, Iwamoto Y, Pivovarov M, Weissleder R, Lee H
Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography.
Sci Rep. 2016;6:24681 - PMID: 27098438 - PMCID: PMC4838824
Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC
A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever.
Sci Rep. 2016;6:32878 - PMID: 27605393 - PMCID: PMC5015101
Jeun M, Park S, Lee H, Lee KH
Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles
Int J Nanomedicine. 2016;2016:11:5497–5503 - PMID: 27799772 - PMCID: PMC5085298
Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE
Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries.
ACS Comb Sci. 2016;18(6):271-8 - PMID: 27124678 - PMCID: PMC5321554
Park KS*, Huang CH*, Lee K, Yoo YE, Castro CM, Weissleder R, Lee H
Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system
Sci Adv. 2016;2(5):e1600300 - PMID: 28861468 - PMCID: PMC5565941
Im H, Lee H, Castro CM
Challenges influencing next generation technologies for precision medicine.
Expert Rev Precis Med Drug Dev. 2016;1(2):121-123 - PMID: 28008420 - PMCID: PMC5166706
Lee H, Shin TH, Cheon J, Weissleder R
Recent Developments in Magnetic Diagnostic Systems
Chem Rev. 2015;115(19):10690-724 - PMID: 26258867
Park KS, Charles RC, Ryan ET, Weissleder R*, Lee H*
Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease
Chem Eur J. 2015;21(46):16359-63 - PMID: 26420633 - PMCID: PMC4816641
Im H, Shao H, Weissleder R, Castro CM, Lee H
Nano-plasmonic exosome diagnostics.
Expert Rev Mol Diagn. 2015;:1-9 - PMID: 25936957 - PMCID: PMC4675626
Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H*
Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor
Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947
Ullal AV*, Peterson V*, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R
Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates
Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113 - PMCID: PMC4063286
Ghazani A, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R
Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance.
Nanomedicine. 2014;10 :661-668 - PMID: 24200523 - PMCID: PMC3966960
Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R*, Lee H*
Magnetic sensing technology for molecular analyses.
Lab Chip. 2014;14(14):2385-97 - PMID: 24887807 - PMCID: PMC4098149
Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R*
Magnetic Ligation Method for Quantitative Detection of MicroRNAs.
Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040
Chung HJ, Castro CM, Im H, Lee H*, Weissleder R*
A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria
Nat Nanotechnol. 2013;8(5):369-75 - PMID: 23644570 - PMCID: PMC3711657
Rho J, Chung J, Im H, Liong M, Shao H, Castro CM, Weissleder R, Lee H
Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles.
ACS Nano. 2013;7(12):11227-33 - PMID: 24295203 - PMCID: PMC3898036
Peterson VM*, Castro CM*, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R
Ascites analysis by a microfluidic chip allows tumor-cell profiling
Proc Natl Acad Sci U S A. 2013;110(51):E4978-86 - PMID: 24297935 - PMCID: PMC3870756
Im H, Oh SH
Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges.
Small. 2013;10(4):680-4 - PMID: 24123889
Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H
Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells.
Lab Chip. 2013;14(1):14-23 - PMID: 23835814 - PMCID: PMC3844052
Issadore D*, Chung HJ*, Chung J, Budin G, Weissleder R*, Lee H*
μHall Chip for Sensitive Detection of Bacteria
Adv Healthc Mater. 2013;2(9):1224-8 - PMID: 23495188 - PMCID: PMC4340655
Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM
Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and miniaturized micro-NMR system.
Nanomedicine (Lond). 2013;9(7):1009-17 - PMID: 23570873 - PMCID: PMC4330975
Chung J*, Issadore D*, Ullal A*, Lee K, Weissleder R*, Lee H*
Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip
Biomicrofluidics. 2013;7(5):54107 - PMID: 24404070 - PMCID: PMC3790798
Issadore D, Chung J*, Shao H*, Liong M, Ghazani AA, Castro CM, Weissleder R*, Lee H*
Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector
Sci Transl Med. 2012;4 (141):141ra92 - PMID: 22764208 - PMCID: PMC3603277 - Cover
Peterson VM, Castro CM, Lee H, Weissleder R
Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing.
ACS Nano. 2012;6(4):3506-13 - PMID: 22424443 - PMCID: PMC3337350
Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H
Magnetic Nanoparticles and microNMR for Diagnostic Applications.
Theranostics. 2012;2(1):55-65 - PMID: 22272219 - PMCID: PMC3263516
Chung J*, Shao H*, Reiner T, Issadore D, Weissleder R, Lee H
Cell Sorting: Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells
Adv Healthc Mater. 2012;1(4):432-6 - PMID: 23184773 - PMCID: PMC3508764 - Cover
Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R
Sensitive and Direct Detection of Circulating Tumor Cells by Multimarker µ-Nuclear Magnetic Resonance.
Neoplasia. 2012;14(5):388-95 - PMID: 22745585 - PMCID: PMC3384426
Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R.
Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples
Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - Cover
Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R
Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles.
ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727
Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R
Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells.
ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118
Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H
Miniature magnetic resonance system for point-of-care diagnostics.
Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660
Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R
Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance.
Bioconjug Chem. 2011;22(12):2390-4 - PMID: 22043803 - PMCID: PMC3263317
Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H
Self-assembled magnetic filter for highly efficient immunomagnetic separation.
Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961
Lee H*, Yoon TJ*, Weissleder R
Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System.
Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069
Lee H*, Yoon TJ*, Figueiredo JL, Swirski FK, Weissleder R
Rapid detection and profiling of cancer cells in fine-needle aspirates.
Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371
Lee H, Sun E, Ham D, Weissleder R
Chip-NMR biosensor for detection and molecular analysis of cells.
Nature Med. 2008;14(8):869-74 - PMID: 18607350 - PMCID: PMC2729055
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