Filip Swirski's Group
Questions
What is the life of an immune cell? When and how does a cell specialize? Where does this occur? How does a particular cell contribute to inflammation and immunity? These are the questions that intrigue my group. We have focused our efforts on charting the life-cycle of myeloid leukocytes in health and its perturbation.
Significance
Our questions are basic and broad, and aim to unravel fundamental mechanisms of the immune system. The answers to our questions are also ultimately translatable to the clinic because the processes they seek to understand are central to many human diseases. Currently, we are interested in atherosclerosis and its complications, but we also interact closely with the Immunology Program at the Center for Systems Biology, the members of which investigate a range of acute and chronic diseases
Approaches
Experiments utilize state-of-the-art animal models, classical cell biology tools, molecular profiling, and in vivo molecular imaging technologies that interrogate cell biology at multiple resolutions, from the whole animal to a single cell. If you are interested in working with us please inquire about availability.
Contact
Filip K. Swirski, PhD
Center for Systems Biology
Massachusetts General Hospital
Harvard Medical School
Simches Research Building, Room 8-226
185 Cambridge Street, Boston, MA, 02114
T: 617-724-6242 | F: 617-643-6133
Email: fswirski@mgh.harvard.edu