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Lee H, Shin TH, Cheon J, Weissleder R
Recent Developments in Magnetic Diagnostic Systems
Chem Rev. 2015;115(19):10690-724 - PMID: 26258867 - PMCID: PMC5791529 - DOI: 10.1021/cr500698d
Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M
Integrative analysis of 111 reference human epigenomes.
Nature. 2015;518(7539):317-30 - PMID: 25693563 - PMCID: PMC4530010 - DOI: 10.1038/nature14248
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE
Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Nature. 2015;529(7584):110-4 - PMID: 26700815 - PMCID: PMC4831574 - DOI: 10.1038/nature16490
Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.
Nat Biotechnol. 2015;33(11):1165-72 - PMID: 26458175 - PMCID: PMC4636926 - DOI: 10.1038/nbt.3383
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
Cell. 2015;160(6):1246-60 - PMID: 25748654 - PMCID: PMC4380877 - DOI: 10.1016/j.cell.2015.02.038
Liu J, Lee J, Salazar Hernandez MA, Mazitschek R, Ozcan U
Treatment of obesity with celastrol.
Cell. 2015;161(5):999-1011 - PMID: 26000480 - PMCID: PMC4768733 - DOI: 10.1016/j.cell.2015.05.011
Garris CS, Pittet MJ
ER Stress in Dendritic Cells Promotes Cancer.
Cell. 2015;161(7):1492-3 - PMID: 26091029 - DOI: 10.1016/j.cell.2015.06.006
Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK
Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.
Science. 2015;347(6227):1260-1265 - PMID: 25766237 - PMCID: PMC4376966 - DOI: 10.1126/science.aaa4268
Nahrendorf M, Swirski FK
Neutrophil-macrophage communication in inflammation and atherosclerosis.
Science. 2015;349(6245):237-8 - PMID: 26185231 - DOI: 10.1126/science.aac7801
Langer R, Weissleder R
Nanotechnology.
JAMA. 2015;313(2):135-136 - PMID: 25585320 - DOI: 10.1001/jama.2014.16315
Nahrendorf M, Swirski FK
Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction
Eur Heart J. 2015;37(11):868-72 - PMID: 26351395 - PMCID: PMC4789592 - DOI: 10.1093/eurheartj/ehv453
Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA
Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo.
Eur Heart J. 2015;38(6):447-455 - PMID: 26685129 - PMCID: PMC5837565 - DOI: 10.1093/eurheartj/ehv677
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
Nat Immunol. 2015;17(2):159-168 - PMID: 26642357 - DOI: 10.1038/ni.3343
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Cell Stem Cell. 2015;16 (5):477-487 - PMID: 25957903 - PMCID: PMC4426344 - DOI: 10.1016/j.stem.2015.04.008
Pfirschke C, Garris C, Pittet MJ
Common TLR5 Mutations Control Cancer Progression.
Cancer Cell. 2015;27(1):1-3 - PMID: 25584886 - DOI: 10.1016/j.ccell.2014.12.008
Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R*, Danuser G*, Mitchison TJ*
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy
Nat Methods. 2015;12(6):577-585 - PMID: 25867850 - PMCID: PMC4579269 - DOI: 10.1038/nmeth.3363
Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB*
Single-cell magnetic imaging using a quantum diamond microscope.
Nat Methods. 2015;12(8):736-738 - PMID: 26098019 - PMCID: PMC4521973 - DOI: 10.1038/nmeth.3449
Kong L, Tang J, Little JP, Yu Y, Lämmermann T, Lin CP, Germain RN, Cui M
Continuous volumetric imaging via an optical phase-locked ultrasound lens.
Nat Methods. 2015;12(8):759-762 - PMID: 26167641 - PMCID: PMC4551496 - DOI: 10.1038/nmeth.3476
Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA
Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus"
Circulation. 2015;131(24):e531-2 - PMID: 26078375 - DOI: 10.1161/CIRCULATIONAHA.115.014802
Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M
Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Circulation. 2015;132(20):1880-90 - PMID: 26358260 - PMCID: PMC4651795 - DOI: 10.1161/CIRCULATIONAHA.115.016160
Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA
Imaging Systemic Inflammatory Networks in Ischemic Heart Disease.
J Am Coll Cardiol. 2015;65(15):1583-1591 - PMID: 25881940 - PMCID: PMC4401833 - DOI: 10.1016/j.jacc.2015.02.034
Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Sci Transl Med. 2015;7(288):288ra77 - PMID: 25995223 - PMCID: PMC4675670 - DOI: 10.1126/scitranslmed.aaa3575
Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamal N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R
Predicting therapeutic nano-medicine efficacy using a companion MR imaging nanoparticle.
Sci Transl Med. 2015;7:314 - PMID: 26582898 - PMCID: PMC5462466 - DOI: 10.1126/scitranslmed.aac6522
Dai N, Zhao L, Wrighting D, Krämer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J
IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins.
Cell Metab. 2015;21(4):609-21 - PMID: 25863250 - PMCID: PMC4663978 - DOI: 10.1016/j.cmet.2015.03.006
Courties G, Herisson F, Sager H, Heidt T, Ye Y, Ying W, Sun Y, Severe N, Dutta P, Scharff J, Scadden D, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M
Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells.
Circ Res. 2015;116(3):407-17 - PMID: 25362208 - PMCID: PMC4312511 - DOI: 10.1161/CIRCRESAHA.116.305207
Nahrendorf M, Swirski FK
Lifestyle Effects on Hematopoiesis and Atherosclerosis.
Circ Res. 2015;116(5):884-894 - PMID: 25722442 - PMCID: PMC4347940 - DOI: 10.1161/CIRCRESAHA.116.303550
Konishi M, Erdem SS, Weissleder R, Lichtman AH, McCarthy J, Libby P
Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis.
Circ Res. 2015;117(6):502-12 - PMID: 26199323 - PMCID: PMC4553143 - DOI: 10.1161/CIRCRESAHA.115.306364
Ye YX, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz GR, Iwamoto Y, Tang J, Perez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, Weissleder R, Tawakol A, Dubey S, Belanger AP, Di Carli MF, Swirski FK, Kjær A, Mulder W, Nahrendorf M
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Circ Res. 2015;117(10):835-45 - PMID: 26394773 - PMCID: PMC4619168 - DOI: 10.1161/CIRCRESAHA.115.307024
van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.
Mol Cell. 2015;61(1):170-80 - PMID: 26687680 - PMCID: PMC4707994 - DOI: 10.1016/j.molcel.2015.11.003
Lee K, Shao H, Weissleder R, Lee H
Acoustic Purification of Extracellular Microvesicles.
ACS Nano. 2015;9(3):2321-7 - PMID: 25672598 - PMCID: PMC4373978 - DOI: 10.1021/nn506538f
Nair AV, Keliher EJ, Core AB, Brown D, Weissleder R
Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo.
ACS Nano. 2015;9(4):3641-53 - PMID: 25790730 - PMCID: PMC4414893 - DOI: 10.1021/acsnano.5b00428
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
Sci Adv. 2015;1(3):ePub - PMID: 26295063 - PMCID: PMC4539616 - DOI: 10.1126/sciadv.1400223
Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H*, Weissleder R*
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Nat Commun. 2015;6:6999 - PMID: 25959588 - PMCID: PMC4430127 - DOI: 10.1038/ncomms7999
Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.
Nat Commun. 2015;6:7029 - PMID: 25967391 - PMCID: PMC4435621 - DOI: 10.1038/ncomms8029
Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.
Nat Commun. 2015;6:8692 - PMID: 26503691 - PMCID: PMC4711745 - DOI: 10.1038/ncomms9692
Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M
Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.
Nat Commun. 2015;6:8803 - PMID: 26541940 - PMCID: PMC4638135 - DOI: 10.1038/ncomms9803
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW
ADAM8 as a drug target in pancreatic cancer.
Nat Commun. 2015;6:6175 - PMID: 25629724 - PMCID: PMC5014123 - DOI: 10.1038/ncomms7175
Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M
Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
J Exp Med. 2015;212(4):497-512 - PMID: 25800955 - PMCID: PMC4387283 - DOI: 10.1084/jem.20141642
Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H
The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.
ACS Cent Sci. 2015;1(3):142-147 - PMID: 26955657 - PMCID: PMC4778250 - DOI: 10.1021/acscentsci.5b00121
Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C
Population dynamics of islet-infiltrating cells in autoimmune diabetes.
Proc Natl Acad Sci U S A. 2015;112(5):1511-6 - PMID: 25605891 - PMCID: PMC4321317 - DOI: 10.1073/pnas.1423769112
Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C Mathis D, Weissleder R
Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
Proc Natl Acad Sci U S A. 2015;112(7):2139-44 - PMID: 25650428 - PMCID: PMC4343112 - DOI: 10.1073/pnas.1424993112
Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H*
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone
Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451 - DOI: 10.1073/pnas.1501815112
Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL
Noninvasive imaging of immune responses.
Proc Natl Acad Sci U S A. 2015;112(19):6146-51 - PMID: 25902531 - PMCID: PMC4434737 - DOI: 10.1073/pnas.1502609112
Di Caprio G, Stokes C, Higgins JM, Schonbrun E
Single-cell measurement of red blood cell oxygen affinity.
Proc Natl Acad Sci U S A. 2015;112(32):9984-9 - PMID: 26216973 - PMCID: PMC4538663 - DOI: 10.1073/pnas.1509252112
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK
AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Proc Natl Acad Sci U S A. 2015;112(32):E4418-27 - PMID: 26216943 - PMCID: PMC4538667 - DOI: 10.1073/pnas.1510604112
Weissleder R, Nahrendorf M
Advancing biomedical imaging
Proc Natl Acad Sci U S A. 2015;112(47):14424-8 - PMID: 26598657 - PMCID: PMC4664297 - DOI: 10.1073/pnas.1508524112
Ryan RJ, Drier Y, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE
Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.
Cancer Discov. 2015;5(10):1058-71 - PMID: 26229090 - PMCID: PMC4592453 - DOI: 10.1158/2159-8290.CD-15-0370
Hong S, Carlson J, Lee H, Weissleder R
Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking.
Adv Healthc Mater. 2015;5(4):421-426 - PMID: 26688173 - PMCID: PMC4811597 - DOI: 10.1002/adhm.201500780
Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression.
Blood. 2015;126(16):1930-9 - PMID: 26320100 - PMCID: PMC4608240 - DOI: 10.1182/blood-2015-06-649087
Tesfay L, Clausen KA, Kim JW, Hedge P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV
Hepcidin regulation in prostate and its disruption in prostate cancer.
Cancer Res. 2015;75(11):2254-63 - PMID: 25858146 - PMCID: PMC4454355 - DOI: 10.1158/0008-5472.CAN-14-2465
Levy O, Mortensen LJ, Boquet G, Tong Z, Perrault C, Benhamou B, Zhang J, Stratton T, Han E, Safaee H, Musabeyezu J, Yang Z, Multon MC, Rothblatt J, Deleuze JF, Lin CP, Karp JM
A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells.
Cell Rep. 2015;10(8):1261-1268 - PMID: 25732817 - PMCID: PMC4361231 - DOI: 10.1016/j.celrep.2015.01.057
Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R
On chip analysis of CNS lymphoma in cerebrospinal fluid.
Theranostics. 2015;5(8):796-804 - PMID: 26000053 - PMCID: PMC4440438 - DOI: 10.7150/thno.11220
Kim JY, Ryu JH, Schellingerhout D, Sun IC, Lee SK, Jeon S, Kim J, Kwon IC, Nahrendorf M, Ahn CH, Kim K, Kim DE
Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.
Theranostics. 2015;5(10):1098-114 - PMID: 26199648 - PMCID: PMC4508499 - DOI: 10.7150/thno.11679
Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA
Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735 - DOI: 10.7150/thno.12494
Vinegoni C, Aguirre AD, Lee S, Weissleder R
Imaging the beating heart in the mouse using intravital microscopy techniques.
Nat Protoc. 2015;10(11):1802-1819 - PMID: 26492138 - PMCID: PMC5380003 - DOI: 10.1038/nprot.2015.119
Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW
Myeloperoxidase Nuclear Imaging for Epileptogenesis.
Radiology. 2015;278(3):822-30 - PMID: 26397127 - PMCID: PMC4770943 - DOI: 10.1148/radiol.2015141922
Koo H, Choi M, Kim E, Hahn SK, Weissleder R, Yun SH
Bioorthogonal Click Chemistry-Based Synthetic Cell Glue.
Small. 2015;11(48):6458-66 - PMID: 26768353 - PMCID: PMC5556392 - DOI: 10.1002/smll.201502972
Teo GS, Yang Z, Carman CV, Karp JM, Lin CP
Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association with Platelets and Neutrophils.
Stem Cells. 2015;33(1):265-277 - PMID: 25263183 - PMCID: PMC4270897 - DOI: 10.1002/stem.1848
Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H
Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease.
Hum Mol Genet. 2015;24(21):6254-63 - PMID: 26310624 - PMCID: PMC4599680 - DOI: 10.1093/hmg/ddv348
Pulli B, Ali M, Iwamoto Y, Zeller MW, Schob S, Linnoila JJ, Chen JW
Myeloperoxidase - Hepatocyte - Stellate Cell Crosstalk Promotes Hepatocyte Injury and Fibrosis in Experimental NASH.
Antioxid Redox Signal. 2015;23(16):1255-1269 - PMID: 26058518 - PMCID: PMC4677570 - DOI: 10.1089/ars.2014.6108
Desai RM, Koshy ST, Hilderbrand SA, Mooney DJ, Joshi NS
Versatile click alginate hydrogels crosslinked via tetrazine-norbornene chemistry.
Biomaterials . 2015;50:30-7 - PMID: 25736493 - DOI: 10.1016/j.biomaterials.2015.01.048
Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
eLife. 2015;4:ePub - PMID: 25998054 - PMCID: PMC4441007 - DOI: 10.7554/eLife.05920
Naxerova K, Elledge SJ
Taking the brakes off telomerase.
eLife. 2015;4:ePub - PMID: 26194808 - PMCID: PMC4507575 - DOI: 10.7554/eLife.09519
Gonçalves I, den Ruijter H, Nahrendorf M, Pasterkamp G
Detecting the vulnerable plaque in patients.
J Intern Med. 2015;278(5):520-30 - PMID: 26306911 - DOI: 10.1111/joim.12414
He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK
Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.
Circ Heart Fail. 2015;8(5):980-7 - PMID: 26232205 - PMCID: PMC4568849 - DOI: 10.1161/CIRCHEARTFAILURE.115.002334
Dutta P, Nahrendorf M
Monocytes in Myocardial Infarction.
Arterioscler Thromb Vasc Biol. 2015;35(5):1066-70 - PMID: 25792449 - PMCID: PMC4409536 - DOI: 10.1161/ATVBAHA.114.304652
Libby P, King K
Biomarkers: A Challenging Conundrum in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2015;35(12):2491-5 - PMID: 26543097 - DOI: 10.1161/ATVBAHA.115.305233
Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJ, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J
Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling.
JACC Cardiovasc Interv. 2015;8(2):355-63 - PMID: 25596792 - PMCID: PMC5645299 - DOI: 10.1016/j.jcin.2014.09.016
Castro CM, Im H, Le C, Lee H, Weissleder R, Birrer MJ
Exploring alternative ovarian cancer biomarkers using innovative nanotechnology strategies.
Cancer Metastasis Rev. 2015;34(1):75-82 - PMID: 25543192 - PMCID: PMC5474936 - DOI: 10.1007/s10555-014-9546-9
Tong T, Yang Z, Chen JW, Zhu J, Yao Z
Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma.
Oncotarget. 2015;6(31):32257-32265 - PMID: 26337080 - PMCID: PMC4741675 - DOI: 10.18632/oncotarget.4899
Nahrendorf M, Dutta P
Targeting splenic hematopoietic stem cells in cardiovascular disease.
Oncotarget. 2015;6(24):19918-9 - PMID: 26343366 - PMCID: PMC4652955 - DOI: 10.18632/oncotarget.4918
Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS,
Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study.
Am J Transplant. 2015;16(1):121-36 - PMID: 26260101 - PMCID: PMC4948061 - DOI: 10.1111/ajt.13422
Siddiquee Z, Smith RN, Stone JR
An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis.
Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884 - DOI: 10.1038/modpathol.2015.105
Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A
Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.
JACC Cardiovasc Imaging. 2015;8(2):121-30 - PMID: 25577441 - PMCID: PMC6855915 - DOI: 10.1016/j.jcmg.2014.10.009
Nahrendorf M, Swirski FK
PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction.
JACC Cardiovasc Imaging. 2015;8(12):1427-9 - PMID: 26699111 - DOI: 10.1016/j.jcmg.2015.10.004
Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH
Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.
Lab Chip. 2015;15(4):1153-9 - PMID: 25553996 - DOI: 10.1039/c4lc01162g
Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R
Advances in measuring single-cell pharmacokinetics and pharmacology in vivo.
Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932 - DOI: 10.1016/j.drudis.2015.05.011
Park KS, Charles RC, Ryan ET, Weissleder R*, Lee H*
Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease
Chem Eur J. 2015;21(46):16359-63 - PMID: 26420633 - PMCID: PMC4816641 - DOI: 10.1002/chem.201502934
Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M
Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation.
J Immunol. 2015;195(3):1282-92 - PMID: 26085679 - PMCID: PMC4506852 - DOI: 10.4049/jimmunol.1401511
Patel H, Patel H, Higgins JM
Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease.
Am J Hematol. 2015;90(5):422-8 - PMID: 25691355 - PMCID: PMC4717489 - DOI: 10.1002/ajh.23982
Hulsmans M, Sam F, Nahrendorf M
Monocyte and macrophage contributions to cardiac remodeling.
J Mol Cell Cardiol. 2015;93:149-55 - PMID: 26593722 - PMCID: PMC4846552 - DOI: 10.1016/j.yjmcc.2015.11.015
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ
Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Inflamm Bowel Dis. 2015;21(11):2507-2514 - PMID: 26241000 - PMCID: PMC4615315 - DOI: 10.1097/MIB.0000000000000524
Guan Y, Meurer M, Raghavan S, Rebane A, Lindquist JR, Santos S, Kats I, Davidson MW, Mazitschek R, Hughes TE, Drobizhev M, Knop M, Shah JV
Live Cell Multi-Photon Fluorescence Correlation Spectroscopy with an Improved Large Stokes Shift Fluorescent Protein.
Mol Biol Cell. 2015;26(11):2054-66 - PMID: 25877871 - PMCID: PMC4472016 - DOI: 10.1091/mbc.E14-10-1473
Kim E, Yang K, Kohler R, Dubach JM, Mikula H, Weissleder R
Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression.
Bioconjug Chem. 2015;26(8):1513-1518 - PMID: 26017814 - PMCID: PMC4772718 - DOI: 10.1021/acs.bioconjchem.5b00152
Park YI, Im H, Weissleder R, Lee H
Nanostar clustering improves the sensitivity of plasmonic assays.
Bioconjug Chem. 2015;26(8):1470-1474 - PMID: 26102604 - PMCID: PMC5292976 - DOI: 10.1021/acs.bioconjchem.5b00343
Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R
Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies.
Bioconjug Chem. 2015;27(1):257-63 - PMID: 26684717 - PMCID: PMC4858350 - DOI: 10.1021/acs.bioconjchem.5b00630
Iaconelli J, Huang JH, Berkovitch SS, Chattopadhyay S, Mazitschek R, Schreiber SL, Haggarty SJ, Karmacharya R
HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells.
ACS Chem Biol. 2015;10(3):883-90 - PMID: 25546293 - PMCID: PMC4372110 - DOI: 10.1021/cb500838r
Pang Y, Tsigkou O, Spencer JA, Lin CP, Neville C, Grottkau B
Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing.
Tissue Eng Part C Methods. 2015;21(10):1025-1031 - PMID: 25962617 - PMCID: PMC4593976 - DOI: 10.1089/ten.TEC.2015.0091
Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R
Single cell resolution in vivo imaging of DNA damage following PARP inhibition
Sci Rep. 2015;5:10129 - PMID: 25984718 - PMCID: PMC4434991 - DOI: 10.1038/srep10129
Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, Hanna RN, Wu R, Swirski FK, Geissmann F, Hedrick CC
The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus.
Sci Rep. 2015;5:10055 - PMID: 26091486 - PMCID: PMC4473761 - DOI: 10.1038/srep10055
Clardy SM, James F. Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R
Rapid, high efficiency isolation of pancreatic ß-cells
Sci Rep. 2015;5:13681 - PMID: 26330153 - PMCID: PMC4557033 - DOI: 10.1038/srep13681
Merkulova M, Păunescu TG, Azroyan A, Marshansky V, Breton S, Brown D
Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.
Sci Rep. 2015;5:14827 - PMID: 26442671 - PMCID: PMC4595830 - DOI: 10.1038/srep14827
Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA
Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging.
Sci Rep. 2015;5:17220 - PMID: 26610702 - PMCID: PMC4661695 - DOI: 10.1038/srep17220
Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA
Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.
Sci Rep. 2015;5:15150 - PMID: 26477568 - PMCID: PMC4609913 - DOI: 10.1038/srep15150
Im H, Shao H, Weissleder R, Castro CM, Lee H
Nano-plasmonic exosome diagnostics.
Expert Rev Mol Diagn. 2015;15(6):725-33 - PMID: 25936957 - PMCID: PMC4675626 - DOI: 10.1586/14737159.2015.1041378
Whitley MJ, Weissleder R, Kirsch DG
Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer.
Semin Radiat Oncol. 2015;25(4):313-21 - PMID: 26384279 - PMCID: PMC4575408 - DOI: 10.1016/j.semradonc.2015.05.005
Kim B, Breton S
The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis.
Biol Reprod. 2015;94(1):22 - PMID: 26658708 - PMCID: PMC4809559 - DOI: 10.1095/biolreprod.115.134965
Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T
Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
J Am Med Inform Assoc. 2015;22(5):993-1000 - PMID: 25929596 - PMCID: PMC4986664 - DOI: 10.1093/jamia/ocv034
Anderson KS, Gerber JE, D'Souza G, Pai SI, Cheng JN, Alam R, Kesiraju S, Chowell D, Gross ND, Haddad R, Gillison ML, Posner M
Biologic predictors of serologic responses to HPV in oropharyngeal cancer: The HOTSPOT study.
Oral Oncol. 2015;51(8):751-8 - PMID: 26094591 - PMCID: PMC4982366 - DOI: 10.1016/j.oraloncology.2015.05.007
Da Silva N, Barton CR
Macrophages and dendritic cells in the post-testicular environment.
Cell Tissue Res. 2015;363(1):97-104 - PMID: 26337514 - PMCID: PMC4703462 - DOI: 10.1007/s00441-015-2270-0
Herak-Kramberger CM, Breljak D, Ljubojević M, Matokanovic M, Lovric M, Rogic D, Brzica H, Vrhovac I, Karaica D, Micek V, Ivkovic Dupor J, Brown D, Sabolic I
Sex-dependent expression of water channel AQP1 along the rat nephron.
Am J Physiol Renal Physiol. 2015;308(8):F809-21 - PMID: 25656365 - PMCID: PMC4398837 - DOI: 10.1152/ajprenal.00368.2014
Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ
Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells.
Am J Physiol Renal Physiol. 2015;309(8):F673-9 - PMID: 26290367 - PMCID: PMC4609919 - DOI: 10.1152/ajprenal.00152.2015
Heng E, Stone JR, Kim JB, Lee H, MacGillivray TE, Sundt TM
Comparative Histology of Aortic Dilatation Associated With Bileaflet Versus Trileaflet Aortic Valves.
Ann Thorac Surg. 2015;100(6):2095-2101 - PMID: 26338050 - DOI: 10.1016/j.athoracsur.2015.05.105
Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.
Eur J Med Chem. 2015;102:320-333 - PMID: 26295174 - DOI: 10.1016/j.ejmech.2015.07.047
Chousterman BG, Swirski FK
Innate Response Activator B cells: origins and functions.
Int Immunol. 2015;27(10):537-41 - PMID: 25957266 - PMCID: PMC4693688 - DOI: 10.1093/intimm/dxv028
Vinegoni C, Lee S, Aguirre AD, Weissleder R
New techniques for motion-artifact-free in vivo cardiac microscopy.
Front Physiol. 2015;6:147 - PMID: 26029116 - PMCID: PMC4428079 - DOI: 10.3389/fphys.2015.00147
Carlucci G, Carney B, Brand C, Kossatz S, Irwin CP, Carlin SD, Keliher EJ, Weber W, Reiner T
Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma.
Mol Imaging Biol. 2015;17(6):848-55 - PMID: 25895168 - PMCID: PMC4609241 - DOI: 10.1007/s11307-015-0858-0
Davis RW, Eggleston H, Johnson F, Nahrendorf M, Bock PE, Peterson T, Panizzi P
In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model.
Mol Imaging Biol. 2015;17(6):793-801 - PMID: 25921659 - PMCID: PMC4807872 - DOI: 10.1007/s11307-015-0856-2
Kim B, Breton S
Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis.
Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361
Kessinger CW, Kim JW, Henke PK, Thompson B, McCarthy JR, Hara T, Sillesen M, Margey RJ, Libby P, Weissleder R, Lin CP, Jaffer FA
Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring.
PLoS ONE. 2015;10(2):e0116621 - PMID: 25680183 - PMCID: PMC4334538 - DOI: 10.1371/journal.pone.0116621
Azroyan A, Cortez-Retamozo V, Bouley R, Liberman R, Ruan YC, Kiselev E, Jacobson KA, Pittet MJ, Brown D, Breton S
Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor.
PLoS ONE. 2015;10(3):e0121419 - PMID: 25799465 - PMCID: PMC4370445 - DOI: 10.1371/journal.pone.0121419
Rotem A, Ram O, Shoresh N, Sperling RA, Schnall-Levin M, Zhang H, Basu A, Bernstein BE, Weitz DA
High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics.
PLoS ONE. 2015;10(5):e0116328 - PMID: 26000628 - PMCID: PMC4441486 - DOI: 10.1371/journal.pone.0116328
Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M
Engineered Trehalose Permeable to Mammalian Cells.
PLoS ONE. 2015;10(6):e0130323 - PMID: 26115179 - PMCID: PMC4482662 - DOI: 10.1371/journal.pone.0130323
Chung HJ, Pellegrini KL, Chung J, Wanigasuriya K, Jayawardene I, Lee K, Lee H, Vaidya VS, Weissleder R
Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury.
PLoS ONE. 2015;10(7):e0133417 - PMID: 26186708 - PMCID: PMC4506142 - DOI: 10.1371/journal.pone.0133417
Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.
PLoS ONE. 2015;10(8):e0136651 - PMID: 26301417 - PMCID: PMC4547801 - DOI: 10.1371/journal.pone.0136651
Rice WL, Li W, Mamuya F, McKee M, Păunescu TG, Lu HA
Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture.
PLoS ONE. 2015;10(7):e0131719 - PMID: 26147297 - PMCID: PMC4493001 - DOI: 10.1371/journal.pone.0131719
Peng S, Wang JW, Karanam B, Wang C, Huh WK, Alvarez RD, Pai SI, Hung CF, Wu TC, Roden RB
Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer.
PLoS ONE. 2015;10(1):e116389 - PMID: 25560237 - PMCID: PMC4283968 - DOI: 10.1371/journal.pone.0116389
Joseph P, Ishai A, MacNabb M, Abdelbaky A, Lavender ZR, Ruskin J, Nahrendorf M, Tawakol A
Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation.
Int J Cardiovasc Imaging. 2015;32(1):113-119 - PMID: 26411879 - PMCID: PMC4730873 - DOI: 10.1007/s10554-015-0766-z
Corey KE, Kartoun U, Zheng H, Shaw SY
Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.
Dig Dis Sci. 2015;61(3):913-9 - PMID: 26537487 - PMCID: PMC4761309 - DOI: 10.1007/s10620-015-3952-x
Da Silva N, Smith TB
Exploring the role of mononuclear phagocytes in the epididymis.
Asian J Androl. 2015;17(4):591-6 - PMID: 25966624 - PMCID: PMC4492049 - DOI: 10.4103/1008-682X.153540
Breton S, Ruan YC, Park YJ, Kim B
Regulation of epithelial function, differentiation, and remodeling in the epididymis.
Asian J Androl. 2015;18(1):3-9 - PMID: 26585699 - PMCID: PMC4736353 - DOI: 10.4103/1008-682X.165946
Li Y, Zhao T, Liu B, Halaweish I, Mazitschek R, Duan X, Alam HB
Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model.
J Trauma Acute Care Surg. 2015;78(2):378-85 - PMID: 25757125 - PMCID: PMC4357277 - DOI: 10.1097/TA.0000000000000510
Kevin Li-Chun H, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW
Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis.
J Neuroimmunol. 2015;287:36-42 - PMID: 26439960 - PMCID: PMC4595933 - DOI: 10.1016/j.jneuroim.2015.08.006
Stone JR, Bruneval P, Angelini A, Bartoloni G, Basso C, Batoroeva L, Buja LM, Butany J, d'Amati G, Fallon JT, Gittenberger-de Groot AC, Gouveia RH, Halushka MK, Kelly KL, Kholova I, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Suvarna SK, Tan CD, Thiene G, van der Wal AC, Veinot JP
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.
Cardiovasc Pathol. 2015;24(5):267-278 - PMID: 26051917 - DOI: 10.1016/j.carpath.2015.05.001
Huck A, Pozdnyakova O, Brunner A, Higgins JM, Fathi AT, Hasserjian RP
Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia.
Leuk Res. 2015;39(10):1034-40 - PMID: 26220865 - PMCID: PMC5764101 - DOI: 10.1016/j.leukres.2015.06.012
Framme C, Walter A, Berger L, Prahs P, Alt C, Theisen-Kunde D, Kowal J, Brinkmann R
Selective Retina Therapy in Acute and Chronic-Recurrent Central Serous Chorioretinopathy.
Ophthalmologica. 2015;234(4):177-188 - PMID: 26368551 - DOI: 10.1159/000439188
Lo Gullo R, Mishra S, Lira DA, Padole A, Otrakji A, Khawaja RD, Pourjabbar S, Singh S, Shepard JO, Digumarthy SR, Kalra MK, Stone JR
Quantification of interstitial fluid on whole body CT: comparison with whole body autopsy.
Forensic Sci Med Pathol. 2015;11(4):488-496 - PMID: 26541472 - DOI: 10.1007/s12024-015-9728-y
Iyer VR, Hedgire SS, Hoskote SS, Borczuk D, Harisinghani MG
Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up.
Abdom Imaging. 2015;40(6):1481-6 - PMID: 25516214 - DOI: 10.1007/s00261-014-0328-1
Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY
Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys.
BMC Nephrol. 2015;16(1):119 - PMID: 26227484 - PMCID: PMC4521488 - DOI: 10.1186/s12882-015-0120-7
Liang JS, Lee SP, Pulli B, Chen JW, Kao SC, Tsang YM, Hsieh KL
Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study.
Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405 - DOI: 10.1016/j.pedneo.2015.10.003
Brettman AD, Tan PH, Tran K, Shaw SY
Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles.
Methods Mol Biol. 2015;1263:15-27 - PMID: 25618333 - PMCID: PMC4357233 - DOI: 10.1007/978-1-4939-2269-7_2
Ullal AV, Weissleder R
Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells.
Methods Mol Biol. 2015;1346:47-54 - PMID: 26542714 - DOI: 10.1007/978-1-4939-2987-0_4
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Acta Neuropathol Commun. 2015;3(1):22 - PMID: 25853389 - PMCID: PMC4382927 - DOI: 10.1186/s40478-015-0201-7
Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, Huang P, Fukumura D, Engelman JA, Jain RK
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment.
J Natl Cancer Inst. 2015;108(2):ePub - PMID: 26547932 - PMCID: PMC4862418 - DOI: 10.1093/jnci/djv313
Naxerova K, Jain RK
Using tumour phylogenetics to identify the roots of metastasis in humans.
Nat Rev Clin Oncol. 2015;12(5):258-72 - PMID: 25601447 - DOI: 10.1038/nrclinonc.2014.238
Pierce RH, Campbell JS, Pai SI, Brody JD, Kohrt HE
In-situ tumor vaccination: Bringing the fight to the tumor.
Hum Vaccin Immunother. 2015;11(8):1901-9 - PMID: 26055074 - PMCID: PMC4635874 - DOI: 10.1080/21645515.2015.1049779
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