Recent Developments in Magnetic Diagnostic Systems
Chem Rev. 2015;115(19):10690-724 - PMID: 26258867
Insulator dysfunction and oncogene activation in IDH mutant gliomas.
Integrative analysis of 111 reference human epigenomes.
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state.
Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis.
ER Stress in Dendritic Cells Promotes Cancer.
Cell. 2015;161(7):1492-3 - PMID: 26091029
Treatment of obesity with celastrol.
Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis.
Neutrophil-macrophage communication in inflammation and atherosclerosis.
Science. 2015;349(6245):237-8 - PMID: 26185231
JAMA. 2015;313(2):135-136 - PMID: 25585320
Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth
Nat Immunol. 2015;17(2):159-168 - PMID: 26642357
Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells
Common TLR5 Mutations Control Cancer Progression.
Cancer Cell. 2015;27(1):1-3 - PMID: 25584886
Single-cell magnetic imaging using a quantum diamond microscope.
In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy
Continuous volumetric imaging via an optical phase-locked ultrasound lens.
IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins.
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Predicting therapeutic nano-medicine efficacy using a companion MR imaging nanoparticle.
Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus"
Circulation. 2015;131(24):e531-2 - PMID: 26078375
Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction
Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo.
Eur Heart J. 2015;38(6):447-455 - PMID: 26685129
Macrophages retain hematopoietic stem cells in the spleen via VCAM-1.
Imaging Systemic Inflammatory Networks in Ischemic Heart Disease.
Acoustic Purification of Extracellular Microvesicles.
Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo.
Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells.
Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis.
Lifestyle Effects on Hematopoiesis and Atherosclerosis.
Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis.
Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug.
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters.
ADAM8 as a drug target in pancreatic cancer.
Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma
Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy.
AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
Single-cell measurement of red blood cell oxygen affinity.
Advancing biomedical imaging
Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone
Noninvasive imaging of immune responses.
Population dynamics of islet-infiltrating cells in autoimmune diabetes.
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression.
Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles.
On chip analysis of CNS lymphoma in cerebrospinal fluid.
Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study.
Hepcidin regulation in prostate and its disruption in prostate cancer.
Imaging the beating heart in the mouse using intravital microscopy techniques.
Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production.
Bioorthogonal Click Chemistry-Based Synthetic Cell Glue.
Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease.
Myeloperoxidase - Hepatocyte - Stellate Cell Crosstalk Promotes Hepatocyte Injury and Fibrosis in Experimental NASH.
Versatile click alginate hydrogels crosslinked via tetrazine-norbornene chemistry.
Biomaterials . 2015;50:30-7 - PMID: 25736493
A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells.
Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages.
Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling.
Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma.
Targeting splenic hematopoietic stem cells in cardiovascular disease.
Myeloperoxidase Nuclear Imaging for Epileptogenesis.
Monocytes in Myocardial Infarction.
Biomarkers: A Challenging Conundrum in Cardiovascular Disease.
Arterioscler Thromb Vasc Biol. 2015;35(12):2491-5 - PMID: 26543097
Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.
Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study.
An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis.
Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884
PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction.
JACC Cardiovasc Imaging. 2015;8(12):1427-9 - PMID: 26699111
Detecting the vulnerable plaque in patients.
J Intern Med. 2015;278(5):520-30 - PMID: 26306911
Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.
Lab Chip. 2015;15(4):1153-9 - PMID: 25553996
Advances in measuring single-cell pharmacokinetics and pharmacology in vivo.
Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking.
Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease
Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.
Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging.
The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus.
Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.
Rapid, high efficiency isolation of pancreatic ß-cells
Single cell resolution in vivo imaging of DNA damage following PARP inhibition
Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation.
HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells.
Monocyte and macrophage contributions to cardiac remodeling.
Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort.
Live Cell Multi-Photon Fluorescence Correlation Spectroscopy with an Improved Large Stokes Shift Fluorescent Protein.
Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression.
Nanostar clustering improves the sensitivity of plasmonic assays.
Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies.
Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing.
Nano-plasmonic exosome diagnostics.
Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer.
The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis.
Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease.
Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics.
Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor.
Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture.
Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring.
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.
Engineered Trehalose Permeable to Mammalian Cells.
Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury.
Macrophages and dendritic cells in the post-testicular environment.
Sex-dependent expression of water channel AQP1 along the rat nephron.
Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells.
Comparative Histology of Aortic Dilatation Associated With Bileaflet Versus Trileaflet Aortic Valves.
Ann Thorac Surg. 2015;100(6):2095-2101 - PMID: 26338050
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.
Eur J Med Chem. 2015;102:320-333 - PMID: 26295174
Innate Response Activator B cells: origins and functions.
Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles.
Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells.
Methods Mol Biol. 2015;1346:47-54 - PMID: 26542714
In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model.
Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma.
Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis.
Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361
Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation.
Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.
Exploring the role of mononuclear phagocytes in the epididymis.
Regulation of epithelial function, differentiation, and remodeling in the epididymis.
Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model.
Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis.
Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.
Cardiovasc Pathol. 2015;24(5):267-278 - PMID: 26051917
Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia.
Leuk Res. 2015;39(10):1034-40 - PMID: 26220865
Selective Retina Therapy in Acute and Chronic-Recurrent Central Serous Chorioretinopathy.
Ophthalmologica. 2015;234(4):177-188 - PMID: 26368551
Quantification of interstitial fluid on whole body CT: comparison with whole body autopsy.
Forensic Sci Med Pathol. 2015;11(4):488-496 - PMID: 26541472
Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys.
Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents.
Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study.
Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation.
The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.